pendotech tff process control & data acquisition system · pendotech tff process control ......

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Product Information PendoTECH TFF Process Control & Data Acquisition System • Ideal for many applications in biopharmaceutical processing: — Ultra-Filtration / diafiltration (UF/DF) of proteins and viruses — Clarification • Adds automation, in-line process monitoring and data collection to your processes • Complete batch control with 6 built-in programable recipes • System interaction via a PC-based Graphical User Interface • Real time trending and all data is written to a file for permanent record • Features use of PendoTECH Pressure Sensors TM that are available from a luer size to 1 inch inner diameter that can be cleaned and re-used extensively; also available in Sanitary Flanges • No process scale limitations • Integrates with different types of pumps and different brands of scales • Built in conductivity, pH & temperature measurements • Options for filtrate flow/flux measurement in addition to ability to measure other process parameters via configurable inputs • Several advanced features afford additional system utility • Built-in data server to exchange data with OPC client software such as PI from OSI soft ® • IQ/OQ templates available Benchtop System Process Development Pilot System www.pendotech.com Tel: +1-609-799-2299 Copyright © 2009-2017 PendoTECH TFFS-REV9

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Page 1: PendoTECH TFF Process Control & Data Acquisition System · PendoTECH TFF Process Control ... • Control system has customized software interface for optimal integration of scales

Product Information

PendoTECH TFF Process Control & Data Acquisition System

• Ideal for many applications in biopharmaceutical processing: —Ultra-Filtration/diafiltration(UF/DF)ofproteinsandviruses —Clarification• Adds automation, in-line process monitoring and data collection to your processes• Complete batch control with 6 built-in programable recipes•SysteminteractionviaaPC-basedGraphicalUserInterface•Realtimetrendingandalldataiswrittentoafileforpermanentrecord•FeaturesuseofPendoTECHPressureSensorsTMthatareavailable

from a luer size to 1 inch inner diameter that can be cleaned and re-usedextensively;alsoavailableinSanitaryFlanges

• No process scale limitations• Integrates with different types of pumps and different brands of scales•Builtinconductivity,pH&temperaturemeasurements•Optionsforfiltrateflow/fluxmeasurementinadditiontoabilitytomeasure otherprocessparametersviaconfigurableinputs•Severaladvancedfeaturesaffordadditionalsystemutility•Built-indataservertoexchangedatawithOPCclientsoftwaresuchas PI from OSI soft® •IQ/OQtemplatesavailable

Benchtop System Process Development Pilot System

www.pendotech.com Tel: +1-609-799-2299 Copyright © 2009-2017 PendoTECH TFFS-REV9

Page 2: PendoTECH TFF Process Control & Data Acquisition System · PendoTECH TFF Process Control ... • Control system has customized software interface for optimal integration of scales

Product Overview

•CompletelyandefficientlyautomatesyourTFF/CrossflowFiltrationProcess•Recipebasedcontrolofentireconcentrationanddiafiltrationprocess withmultipleoptionsforautomateddiafiltrationendpoint(filtrateweight,conductivity,pH,airinbufferfeedline,totalflow)

•Pressuremeasurementinpsiorbarandcalculationoftrans-membranepressure(TMP)anddelta-PwithPendoTECHPressureSensorsthatareavailablefromaluersizeto1inchinnerdiameterthatcanbecleanedand re-usedextensivelyorothersensorssuchasstainlesssteeltransducers

•Interactwiththesystemviaaneasytousegraphicaluserinterface(GUI)thatincludesatrendingmodulewithmanyadvancedfeatures

•DatacollectiontoafilethatisopenedwithExcel• Alarms for all process parameters that shut-down the pumps• Alarm features include a delayed detection on the minimum inlet pressure that canstopthesystemiftheinletpressuredropsduetoaflowpathproblem

• Automation and alarm features allow the system to be operated with minimal user interaction

• Stainless steel design with completely sealed front panel for use in clean environmentswherefrequentwipe-downisrequiredandNaOHisused•Processcontrolviaintegrationofindustrystandardscalesandpumps• Can be used at any process scale•pHprobeinputviaaBNCconnectorthatcanaccommodatestandardpHprobesandtheGUIincludesaneasytouseprobecalibrationwizard

•Conductivityprobe/flowcellinputtoembeddedconductivitytransmitter with temperature display and compensation

• Air detector end-point can be used for “Fed-batch” process where product is fedtothemainvesselanddynamicallyconcentratedviadiafiltrationmode•Filtrateflowmeterinputforoptionalrotaryflowmeter, ultrasonicflowmeter,orotherthatincludestheabilitytototalizeflow

•Temperaturesensorinputforan“in-line”sensororfordiptubesensor•Twoinputsavailableforothersensorswith4-20milliampoutputsto enablecollectionofadditionalprocessdatathatcanbeconfiguredfor advancedfeaturesandalarmspointssuchasUVoranadditionalflowmeter

•ThesystemmaybecontrolledremotelyviaaPC,iPadorsmartphoneby using3rdpartysoftware.Processdetailsarevisualizedonthegraphical interfaceandthesysteminteractionisviathePCsoremotecontrolis possiblebysimplyaccessingthePC•Notificationsappearonsoftwarescreenwhenparametersareoutofrangeand with built-in email client can send email/text message alerts.•Retentateflowmaybecontrolledbyuseofaretentateflowmeter•SystemhasTMPoutputsignalthatcanbeconnectedtoexternal non-invasivecontrolvalvetocontrolsystemTMP•Built-indataservertoexchangedatawithOPCclientsoftwaresuchas PIfromOSIsoft®

•CEtestedforEMCandLVD

Graphical User Interface - Simplifies Control System InteractionTheGUIisdesignedforusewithamouseortouch-screenoperation.Clickinganumericfieldisfollowedbyappearanceofapop-upkeypadfordataentry.Valuesenteredthatareoutofrangearerejectedwithamessage.Therearefourtabsforeasynavigation:

4TabsforFastandEasyNavigation

(systemviewshown)

Notes-Clickhereandapop-upboxappears where an electronic note can be entered. Thenoteiswrittentothedatafileonetime

and time-stamped.

Notifications-Givenotifications butdonottriggeranalarm.Thesecanbe

enabled to send email alerts also.

Critical Alarm - Critical alarm that stops pumps appearshereinRED.

1.SetupView-usedtoenterexperimentinformation,programrecipe,setalarmsandtocreateadatafilewhereallprocessdata will be stored

2.SystemView-usedtoviewcurrentprocessvaluesand changepumpflowrates

3.TrendsView-utilitytotrendprocessvariablesthatisloadedwithfeaturestodynamicallyviewthedataofinterest,ability toquicklyauto-scaleormanuallyscaletheaxes,andability toexportatrendofinteresteitherasdataoragraphicsfile; abilityforinstantopeningofdataofinterestinExcel

4.MaintenanceView-usedtosetuppumpsbasedonpump parameters,calibratepHandconductivityviaeasytousewizards,configureflowmeterandmore.

Thesystemviewcanbecustomizedwithselectionofahollow fiberorcassettemodulegraphicandwiththeabilitytoenable/ disablethefiltratepump.

2www.pendotech.com Tel: +1-609-799-2299

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Process Overview

TFF/Cross Flow Filtration Process Overview Atangentialflowfiltration(TFF)orcrossflowfiltrationprocessusingahollowfiberfiltermodule(versusaplate&framecassetteflatsheetdevice)isrepresentedinFigure1.

Liquidisfedfromaproductvesselbyacirculationpumptoafiltermodulecontainingnumeroushollowfibersandtheliquidflowsintotheinnercrosssectionoftheindividualfibers.

Thewallofthehollowfiberisthefiltermembrane.AsisshowninFigure2,acertainamountofliquidandliquidcomponentssmallerthantheporesizeofthefiberwall“permeates”throughthewall(thefiltrate).Thefiltratecollectsinthemoduleshellandtheshellhasportsforremovaloffiltratefromtheshell(thevoidareabetweenthefibersisclosedatbothendstopreventtheliquidthatisenteringthefiltermodulefromgoingdirectlyintotheshell).Thefeedpressure(PIN)ishigherthantheretentatepressurein(POUT)becauseofthepressuredropasliquidflowsthroughthenarrowfibersandreturnstothevessel.ThereisalsoapressuredropacrossthefiberwallandthefiltratepressureismeasuredatPF.Monitoringofthesepressuresiscriticaltomeasure processperformanceandforprocesscontrol.Thecrossflowrateisordersof magnitudeabovethefiltrateflowrateanditisthisphenomenathatpreventsamembranefilterfromcloggingfrommaterialthatwouldrapidlyclogamembranefilteroperatingin“normalflow”filtration.Inflatsheetdevices,eventhoughthegeometryofthedeviceisdifferent,theoperationoftheprocessissimilar.TFFisaveryeffectiveprocessselectioninmanyareasofbiopharmaceuticalprocessing.Dependingontheprocess,afiltratepumpmaybeusedtolimitthefiltrateflowandpreventrapidfilterfouling.Athrottlingvalvemaybeusedontheretentatetubetocreatebackpressuretodriveliquidthroughthemembrane.InaTFFprocess,asfiltrateisremoved,thevesselcontentsareconcentrated.Inadiafiltrationprocess,liquidisaddedtotheproduct vesselasthesamerateoffiltrateremoval.

Buffer FeedPump

Flow

Flow

Scale

Scale

Data

FlowFlow

Buffer ContainerCross Flow

CrossFlow

CirculationPump

MainVessel

Pressuresensor

FlowMeter

pHsensor

Conductivitysensor

Product Container

DV1 DV2

TFFControlSystem

GraphicalUser

Interface

PressureControlValve

Solenoid

Process Schematic with Available Inputs and Outputs

3Copyright © 2009-2017 PendoTECH TFFS-REV9

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User Interface Details

Enterexperimentinformation,program recipe,setalarmsandcreatesadatafile

where all process data will be stored

Information is written to header of data filewhendata

collectionisstarted; then it becomes

uneditable

System

Setup

Abilitytosave/recallfrequentlyusedrecipes

WhenStartProcessData Collection is selected,

a dialog box appears so afilenameandlocationcanbe

entered. All process data issavedtoaCSVfile

that can be opened later insoftwaresuchasExcel.

Recipe Info

Estimatedflowratecan be calculated by an

algorithm based on the changeinfiltrate

scale rate.Pumpsrotatewhile running

Externalsensor

readings

Indicators in blue can be changed while running by clickingontheindicator

Flow only appears if flowmeterconfigured

Allprocessvariablesaredisplayed including

calculatedvaluessuch asTMPandDeltaP

6optionsavailable

Filtrate pump appears here only if enabled

6Diafiltrationendpointoptionslisted

Pumpsprogrammed for different steps

Settings for selected recipe are entered heree

Alarms set-pointswill stop pumps

Notificationpoints (createnoaction)

Viewcurrentprocessvalues andchangepumpflowrates

Gaugerangessetbymin/max alarm set

points

Configurenotificationemail or text message

alerts

4www.pendotech.com Tel: +1-609-799-2299

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Trends

Maintenance

Options to select Auto-scale or Manualscaleonallaxes

Slidetochangecursorvalue

Powerfultoolstozoom,export an image of

the current trend and much more

Quicklycomparecurrentvalues tocursorvalue

Exportthecurrenttrendonly to open in software

suchasExcel

Ability to change plot update rate

pHwizardzoom

Functions Include:• Zero pressure sensors•Enable/disablefiltratepump•Selectconductivityrange•CalibratepH• Set units of measure• Set-up pumps•Selectgraphicdisplayforfilter•Configuretheflowmeter•Zeroflowmetertotal• Set range of external signals•Enable/disableDiafiltrationValves•Exitprogram

Utilitytotrendprocessvariableswith featurestoviewthedataofinterest,autoormanualscaletheaxes,&exportatrendas

adataorgraphicsfile

Use to set up pumps based on tubing size, calibratepH&conductivityviawizards,selectunitsofmeasure,configureflowmeter&more

FiltrateFlowMeterthatisalsousedtodetermineflux,hasachoiceofflowmetersthatsettheK-factorfortheflowmeter or the K-factor may be entered

manually or determined by a user calibration wizard.

5Copyright © 2009-2017 PendoTECH TFFS-REV9

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Integration Options

Control System Back Panel Input/Output Connections

Scale Options Filtrate Flowmeter Options

PendoTECH Throttle ValveTM Option

Thesystemcomeswiththerequiredcablestoenablethesytemtobequicklyupandrunning.Allconnectionsarekeyedtopreventconnectionofacabletothewrongconnector.Pumpsandscalesmaybedeliveredwiththesystemorexistingequipmentorself-procuredequipmentmaybeused.

Thevalvereceivesthepressuresignalfrom the control system and controls backpressurebyvaryingtheflowpatharea by only contacting the outside of thetubingwithoutthevalvecontactingthefluid.Itincludesone-touchreal-timeadjustment of the proportional setting for thePIDcontroltoaccountfordifferentpumps and system setups.

•MostscaleswithRS232communicationcanbeused • Control system has customized software interface for optimal integration of scales to enhance performance • A scale selection menu on the process control system is used toquicklyconfiguretheRS232parametersforthedifferent scale brands.

Rotary Flowmeter

PendoTECH Coriolis

Forfiltrateflowmeasurement,fluxcalculation,andtotalflow measurement,thereisaFiltrateFlowMeterinputonthebackpanel.Thisreadsadigitalpulse/frequencyinputsignalthatisanavailableoutputonmanyflowmeters.Thefiltrateflowmetercanbeabasicflowmeasurementtechnologybecausethefluidbeingmeasuredisclean,filteredmaterialwithrelativelyconsistentviscosity.TheLowFlowUltrasonicFlowMeteriscapableofmeasuringflowsinadifficulttomeasureflowrangeof2to100mL/minute.Ithasa1/16inchIDx1/8inchODandaluerfittinginletfittingforeasyconnection.Therotaryflowmetershavea¼inchhosebarbandcanmeasureflowsfromabout0.1to1Liter/minuteora½inchbarbthatcanmeasureflowsfrom0.3to20Liter/min.

6

Retentate Flowmeter Options

E+H Mag Flowmeter

ForretentateflowwheretheremaybeashiftinviscosityflowmustbemeasuredbyothertypesofflowmeterssuchasthePendoTECH CoriolisFlowMeterormagneticflowmeasurementtechnology.Thereare3modelsofthePendoTECHCoriolisFlowMetercoveringtherangefrom5to24,000g/minuteandtheE+HPromagcanmeasurefrom2to45L/minute.TheseflowmetersconnectintotheAnalogInput2connectoronthebackpanelwhichisa4-20mAanaloginputsignal.The4mAand20mAoutputrangeoftheflowmeterinL/minuteis entered into the software. Connecting to this input, integrates the reading into the option Retentate Flow Control algorithm.

www.pendotech.com Tel: +1-609-799-2299

Low Flow Ultrasonic Leviflow Sensor

Montor

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Integration Options

Pressuresensorcablesprovidedwiththesystemacceptthe PendoTECHPressureSensors(below).Eventhoughthesearecalled single use, they are robust enough to be re-used for process developmentworkwherecross-contaminationisnotaconcern.Sizesavailableluer,1/4”,1/2”,3/8”,1/2”,3/4”and1”hosebarb, alsoinsanitaryflange.Ultrasecuretubingretainersareavailablefor higher pressure operations.

Pump Options

Pump Cable (Masterflex Pump

Cable Shown)

Example of Pump Back Panel with remote interface

connector

Interface Connector

Pressure Sensors

• Any pump with a remote speed control input can be used- no process scale limitations! •Peristaltic,rotarylobe,diaphragmpump,andother •PumpSetupfunctionusedtoquicklyenterthepumpparameters •MasterflexpumpselectionguideavailablefromPendoTECH • Thepumpcablesaresuppliedtointerfacetotheremote control connector on the user selected pumps as shown in the example below.

Following is a selection of just some of the pumps that can be integrated to the system

Other sensors such as Stainless Steel transducers with full bridge-4wireoutputmaybeused.

7

Air Detector Option

Thenon-invasiveultrasonicairdetectordetectsairinatubeplacedintothedetector.ThereisanintegralLEDthatindicatesliquidpresence.Thetubecanbeopaquebecausethesensingmechanismissoundwaves.Thesoftwarehasauserentereddetectiondelaytopreventfalseendpoints.

TheAirDetectorwhichdetectsthedifferencebetweenairandliquidinatube,isintegratedintothesoftwareasaDiafiltrationEndpoint.Thiscanbeusedprimarilyinoneoftwoways.Oneistorunafed-batchprocesswhereliquidiscontinuouslyfedtoallowabatchtobecontinuouslyaddedtothevesselwhichsimultaneouslyconcentrates.Thisgivesmoreflexibilitytoadefinedsetupandcanassistinminimizationoftheoverall systemhold-upbyminimizingthevesselsize.Secondly,itcanbeforusedwithapre-measuredbuffervolumeforadiafiltrationstep.

Copyright © 2009-2017 PendoTECH TFFS-REV9

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Integration Options

Built-in Conductivity & Temperature Monitor

Conductivity Probe Options:

8

Built-inconductivitymonitoralsomeasures temperature and performs temperature compensation.Thereisasimpleone-stepcalibration procedure and probes with constantsofK=1orK=10maybeused.Therangeisselectablefromeither0-19.99mSor0-199.9mS.Differentflowcellordipprobeoptionsareavailable.

pH

Epoxy dip probe

Small scale with luer or barb inlet/outlet

Flange probe

Stainless probe in flow cell with either barb or flange

inlet/outlet

TemperatureTemperatureisdisplayedinthesoftwaresystemviewandrecordedinthedatafile.Thereareseveraloptionstomeasuretemperature-eitheraluerfittingforsmallscale,andin-linehosebarbsensors,andadipprobe.

pHmeasurementisintegratedtothesystem.AnystandardpHprobethathasaBNCcircularconnectorcanbeused.PendoTECHoffers2in-lineoptions:oneforLab/Developmentwitheitheralueror1/4inchhosebarbandoneforPilotscalewitha¾inchsanitaryflange.Inbothdesigns,theprobecanberemovedfromthecellforcalibrationwithbuffersusingthesoftware’spHcali-brationwizard.Thelabscaleprobeslidespastao-ringsealtogivetheprobetipaccesstothefluidpathandthehold-upvolumeislessthan1mL.ThePilotscaleprobehasa12mmODandissecuredinthecustomdesignedflowcellviaacompressionfitting.ThecompressionferrulesaremadefromPTFEsotheycanslideuptheprobeorremovedfromtheprobe.

Conductivity

www.pendotech.com Tel: +1-609-799-2299

Diafiltrationvalvesworkwiththeairdetectorend-pointandcanbe used for “Fed-batch” process where product is fed to the main vesselanddynamicallyconcentratedviadiafiltrationmode.Aftertheconcentrationstepthevalvesswitchtobufferandthe diafiltrationpumpwillthendrawinbufferforthatstep.

Diafiltration Valves

Page 9: PendoTECH TFF Process Control & Data Acquisition System · PendoTECH TFF Process Control ... • Control system has customized software interface for optimal integration of scales

Vessel Detail - 2 Liter Vessel shown

BufferFeed& Retentate tubes

can be positioned todeliverliquidto the bottom

Topandbaseattached by

sanitary clamps

Stand with adjustable legs

for different stir plates

Removablecollars for tube

adjustment/removal

Spare hole forventingor recycle

Vesselmadeof polysulfone - easilyremoved

for cleaningConical base with

low point drain

Stir bar locator in the center of the base

PendoTECH Vessel Options

2L 500mL 125mL

VesselswithLowHoldupVolume-thekeytominimizingoverallsystemholdup.Allhaveaconicalbottomwithmixing and a low point drain.

Vessel Options

Copyright © 2009-2017 PendoTECH TFFS-REV9 9

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Benchtop Systems

DiafiltrationFeed SelectionPinch

Valves

AirDetectorFor Fed BatchEnd

Point

Retentate FlowMeter

ThrottleValve

Circulation Pump

LowFlowFiltrate Flow

Meter

PCforGraphicalUser Interface

Diafiltration feed pump

Vessel with stirrer

Cond. Flow Cell

Scales

PressureSensors

Control SystemThrottleValve

Controller

Small Scale Benchtop Setup

10Copyright © 2009-2017 PendoTECH TFFS-REV9

Development Scale Benchtop Setup

Page 11: PendoTECH TFF Process Control & Data Acquisition System · PendoTECH TFF Process Control ... • Control system has customized software interface for optimal integration of scales

HeavyDuty LockingCasters

2LiterVesselwithStirrerConicalBottomWithLowPointDrain

DiafiltrationFeed SelectionPinch

Valves

Diafiltration FeedPump

Retentate FlowMeter

ThrottleValve

Circulation Pump

PCforGraphicalUser Interface with Touch-Screen

PressureSensors

Control System

ThrottleValve

Controller

Filtrate Scale

AirDetectorForFedBatchEndPoint

Filtrate FlowMeter

Scale

Waterproofintegralkeyboard/mouse on slideout tray

Process Development Carts

11www.pendotech.com Tel: +1-609-799-2299

Q1200 Pump Setup Masterflex L/S Pump Setup

Q150 Pump Setup

Page 12: PendoTECH TFF Process Control & Data Acquisition System · PendoTECH TFF Process Control ... • Control system has customized software interface for optimal integration of scales

Integrated Cart Systems

Pilot cart shown with push-up cart with larger pump demonstrates system flexibility that is

required in Pilot environments.

Pilot System

WaterResistantPCforGraphicalUserInterfacewithTouch-Screen

andWirelessNetworking

Control System

30LiterVesselwithStirrerwithBottomDrain

DiafiltrationFeedSelectionPinchValves

DiafiltrationFeedPump

HeavyDutyLockingCastersforMoving

ThrottleValveController

Retentate Flow Meter(optional-not

shown)ThrottleValve

PressureSensors Surface for Filter

FiltrateFlowMeter

ConductivityFlowCell

PinchValvesFor AutomatedRecovery

CirculationPumpScales

AirDetectorFor Fed Batch EndPoint

Cart shown with I/P Diafiltration Pump and Mag Retentate Flow Meter mounted in-line

Copyright © 2009-2017 PendoTECH TFFS-REV9 12

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Advanced Features

•EasyabilitytooperatesystemremotelyfromanotherPCusing softwaresuchasRealVNC,RemoteDesktop,Timbuktu, GoToMyPC,LogMeInandothersorsmartdevicessuchasthe iPhone/iPad

Remote Access

Circulation Pump Control

Email & Text Message Notification

External Input

•OptionsforRetentateFlowControlwhichadjuststheflowrateofthecirculationpump: •ARetentateflowsetpointcanbecontrolledbyenablingthisfeatureand installingaretentateflowmetersuchasthePendoTECHCoriolisFlowMeter •DeltaPcanbecontrolledbytheGUIsoftware“FlowAdjust”algorithmby enteringtheDeltaPsetpointThesemodesareactivatedontheMaintenanceTab.Additionalcontrolsettingsareaddedtotheothertabstooptimizethesefeatures.Somefiltermanufacturers recommendoperationinthesemodes.ThesemodesworksindependentofautomatedTMPcontrol.

Thetwoexternalinputscanbeusedtocollectdatafromawidevarietyofsensorsnotbuiltintothesystem.Theinputsignalsareconfiguredinthesoftwareandalarmpointsonthesevaluesmaybeenteredalso.TheseinputsgivetheabilitytoinstantlyintegratethePendoTECH TemperatureSensorsandUVSensors.

Thepre-alarmnotificationpointscanbeusedtosendemailalertsandtextmessages.Thesystemisgivenanameandtheemailaddressestosendthealertsareentered.Thereisabuilt-inmailprogramtosendthesenotificationswithadefaultmailboxwhichmaybereplacedbyauserconfiguredmailbox.

[email protected]

13

UV Sensor with Transmitter

www.pendotech.com Tel: +1-609-799-2299

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Specifications

Detail SpecificationsDimensions(HxWxD) 6.125”x16”x11.5”(15.5575cmx40.64cmx29.21cm)

Weight 8lbs(3.6kg)

EnclosureMaterial 304StainlessSteel

PowerRequirements 100-240Volts,50-60Hertz,2ampmax

PressureSensorInputs PendoTECHPressureSensorsdefaultconfiguration- other full-bridge type sensors optional

PumpControl SpeedControl:4-20mA;CircPumpAlternate:Scalablevoltagesignalwithin0-10volts Start/Stop:Relay3-48VDC,upto3Acontinuous

AIrDetectorInput Digitalinputwith24VDCsupply

FlowMeterInput 5VDigitalpulseinputwith5VDCor24VDCsupply

ExternalInputs AnalogSignal-both4-20mA

pHInput StandardprobeinputviaBNCconnector

ConductivityInput 4wireinput(2wiresfor100ohmPtRTD)K=1orK=10withrangeselectableforeither0-19.99mSor0-199.9mS

Scale Inputs RS232Communication

TemperatureInputs 2-wire2252ohmthermistorinputdesignedforusethePendoTECHtemperaturesensorsavailableinaluerdesign,in-linewithahosebarbandadipprobe.

PCRequirements Windows7or10,2GHzorfaster,2GBofRAM

SYSTEMPDKT-PCS-TFF TFFProcessControlSystemwithGraphicalUserInterfaceSoftwareandinterfacecables

PUMPS (Others Available)PUMP-MF-LS-TW MasterflexGeneralPurposeDigital,withRPMdisplayonly,600RPMwithEasyLoadIIpumpheadforthinwallL/StubingsPUMP-MF-LS-TKW MasterflexGeneralPurposeDigital,withRPMdisplayonly,600RPMwithEasyLoadIIpumpheadforthickwallL/StubingsPUMP-MF-LS-HP MasterflexGeneralPurposeDigital,withRPMdisplayonly,600RPMwithHighPerformancepumpheadforthickwallL/StubingsPUMP-WM-120-TW Watson-Marlow120U/DV200RPMPumpFittedwith114DVflip-topfourrollerpumpheadforthintubingPUMP-WM-620 WatsonMarlowModel620U/R265RPMPumpwithFlowto12.7l/minPUMP-Q150SU QuattroPumpQ150SingleUsechamber(upto3L/min)andincludes3chambersPUMP-Q150SS QuattroPumpQ150Stainlesssteelchamber(upto3L/min)PUMP-Q1200SU QuattroPumpQ12003°PumpSingleUsechamber(upto11L/min)andincludes3chambersPUMP-Q1200SS QuattroPumpQ12003°PumpStainlesssteelchamber(upto11L/min)PUMP-Q1200HSU QuattroPumpQ12005°PumpSingleUsechamber(upto18.3L/min)andincludes3chambersPUMP-Q1200HSS QuattroPumpQ12005°PumpStainlesssteelchamber(upto18.3L/min)

PUMP-KN-LS MiniDiaphragmPumpwithKNFFEMPumpHeadw/M12remotecontrolportforcontrolfromsystem,2to90mL/min

FLOW METERS

FILTRATEFLOWMETERS

FM-22WV RotorforDisposablePVDFTurbineFlowmeter1/4inch,0.1-1.0LPM,clipmount.Withindividualcalibrations.

FM-22WV-E ElectronicAssemblyforonePVDFrotorwith1/4inchhosebarb(includesonerotor),0.1-1.0LPMclipmount.Withindividualcalibrations.

FM-23WV SingleUseRotaryFlowMeter,non-sterile,PVDF,1/2inchhosebarb,0.3-20.0LPM,clipmount.Withindividualcalibrations.

FM-23WV-E ElectronicAssemblyforonePVDFrotorwith1/2inchhosebarb(includesonerotor),0.3-20.0LPM,clipmount.Withindividualcalibrations.

FM-US-LF-I PendoTECHLowFlowUltrasonicFlowMeter(1/16inID),flowrange2-100mL/minwithnodisplay,Freqsignalwith6feet(2meters)cableforconnectiontoPendoTECHProcessControlSystem

RETENTATEFLOWMETERS

PCFM-31 PendoTECHCoriolisMassFlowmeterwith0.25”/6.35mmID(range5-1,500grams/min)

PCFM-32 PendoTECHCoriolisMassFlowmeterwith0.25”/6.35mmID(range5-4,000grams/min)

PCFM-82 PendoTECHCoriolisMassFlowmeterwith0.25”/6.35mmID(range750-24,000grams/min)FM-EH-MAG-53H15 E+HPromag53H15,DN151/2”ElectromagneticFlowmeter,2-50LPM,120Vpluginstalled,4-20mAoutputforintegration,

1/2inchID,316LTCinlet/outlet,integraldisplaywithtouchcontrol-includesbracket&mount14

Ordering Information

Copyright © 2009-2017 PendoTECH TFFS-REV9

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Ordering Information

15

CONDUCTIVITY COND1-TFF ConductivityProbeK=1with100ohmPtRTDfortemperaturemeasurementforTFFProcessControlSystem,stainlesssteelwithflowcellCOND2-TFF ConductivityProbeK=1with100ohmPtRTDfortemperaturemeasurementforTFFProcessControlSystem,epoxyCOND3-TFF ConductivityGlassflowcellK=1for1/4”IDtubingw/100ohmPtRTDfortemperaturemeasurementforTFFProcessControlSystemCOND4-TFF ConductivityProbeK=1with100ohmPtRTDfortemperaturemeasurementforTFFProcessControlSystem,stainlesssteelwithsanitaryflange

AIR DETECTOR

PartNumber AD-16 AD-17 AD-73TubingOD 1/4” 3/8” 5/8”

DIAFILTRATION VALVEPDKT-PVE2-TFF-S TFFControlSystemElectricDiafiltrationPinchValvePair-Smallfor1/8inchIDPDKT-PVE2-TFF-M TFFControlSystemElectricDiafiltrationPinchValvePair-Mediumfor1/4inchID

pH

PH-GFCP pHprobeforflowcell

PH-GFCC pHprobe&flowcellwith1/4inchbarborluerforlabscale

PH-PILOT-C pHpilotscaleflowcellwith3/4inchsanitaryflangeinlet/outletsfor12mmODprobe

PH-PILOT-CP 12mmODpHprobeforflowcell

PH-PILOT-CC pHpilotscaleflowcellwith3/4inchsanitaryflangeinlet/outletswith12mmODpHprobe

Warranty/Disclaimer

VESSELSPDKT-TNK Complete2Ltanksetupwithstirplate,2diptubes,andstandTNK-2L-STRPLATE Stirrerplatefor2litervesselPDKT-TNK500M 500mL-2.5inchdiameter(basewithoutlet,vessel,lidwith2tubeholdersanddiptubes)-(DOESNOTINCLUDESTIRPLATE)PDKT-TNK125M 125mL-1.5inchdiameter(basewithoutlet,vessel,lidwith2tubeholdersanddiptubes)-(DOESNOTINCLUDESTIRPLATE

Alldescriptions,representationsand/orotherinformationconcerningProductonthePendoTECHwebsiteand/orcontainedinPendoTECH’sadvertisements,brochures,promotionalmaterial, orstatementsmadebyemployeesorsalesrepresentativesofPendoTECHaresolelyforgeneralinformationalpurposesonlyandarenotbindinguponPendoTECH.Noemployeeorsales representativeofPendoTECHshallhaveanyauthoritytoestablish,expandorotherwisemodifyPendoTECH’swarrantyassociatedwiththesaleofProduct.PendoTECH,LLCmakesno warrantyorrepresentationregardingwhetherornotacustomer’senduseofanyPendoTECHproductorsysteminfringesthevalidintellectualpropertyrightsofothers.PendoTECHdoesnotdirectorinstructcustomerstouseanyPendoTECHproductorsystemincombinationwithparticularcommerciallyavailablepre-sterilizedmanifolds,remotelyoperatedpinchvalves,assuch usecouldpossiblybecoveredbytheclaimsofoneormorepatents.PendoTECHshallnotbeliabletoBUYERinanymannerwithrespecttoProductsold.SELLER,PendoTECHMAKES NOREPRESENTATIONSORWARRANTIESOFANYTYPE,EXPRESSORIMPLIED,ANDEXPRESSLYDISCLAIMSANDEXCLUDESANYREPRESENTATIONORWARRANTYOF MERCHANTABILITY,FITNESSFORAPARTICULARPURPOSEORUSE,NON-INFRINGEMENTORWARRANTYARISINGFROMUSAGEOFTRADE,COURSEOFDEALINGOR PERFORMANCE.”

For warranty information see our website at http://www.pendotech.com/warranty

CARTSCART-TFF-COMPACT TFFControlSystemcompactcartwithslidetraywithtouch-screenmonitorandwater-proofkeyboard(PCnotincluded)PDKT-TFF-CART1 UF/DFPilotCartSystemincludesPanelMountNEMA4XtouchscreenPC(NOAXIndustrialStainlessSteelPC,IP-66Rating,24VDC,

15inchTFT-Display1024x768,Ethernet,Intel8255110/100w/RJ45,USB, Windows7PRO,Wireless)

FOR PENDOTECH PRESSURE SENSORS

See www.pendotech.com/pressure

FOR PENDOTECH TEMPERATURE SENSORS

See www.pendotech.com/temperature

www.pendotech.com Tel: +1-609-799-2299 Copyright © 2009-2017 PendoTECH TFFS-REV9