paeds & neonates 2011.pdf
TRANSCRIPT
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Paediatric & Neonatal Resuscitation
Guidelines 2011, Singapore
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2010 ILCOR review:
Paediatric Life Support
Task force identified 55 questions related to Paeds Resus
Evidence review by 2 or more independent reviewers for each topic Draft Consensus on Science and Treatment Recommendations Re-circulated and refined until consensus reached
Controversial / critical topics addressed at 2010 ILCOR conference
Final Consensus on Science and Treatment Recommendationspublished
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The Singapore National Resuscitation Council, Neonatal &
Paediatric Resuscitation Workgroup, 2010-2011
Chairman
Ng Kee-ChongKKH CICUDr Janil Puthucheary
Dr Chan Yoke HweeDr Siti Buang
Dr Irene Chan (VC)KKH Paeds Anaesthesia
A/Prof Agnes Ng
Dr Josephine Tan
KKH -CEDr Peter Wong
Dr Chong Shu-LingNUH - PICUDr Diana Lin
NUH - CEDr Kao Pao Tang
Neonatal Subcommittee
A/Prof Lee Jiun (NUH Neonates)
A/Prof Yeo CL (SGH-Neonates)
Dr Quek BH (KKH Neonates)
Dr Kenny Ee (Private)
Nursing Reps
ADN Lee Siew Kum
ADN Ong Lim Liew
SNM Tor Sow Khim
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1) BASIC PAEDIATRIC LIFE
SUPPORT
1a) RECOGNITION & ASSESSMENT OF
CARDIAC ARREST
One should take not more than 10 seconds todetermine if there is cardiac arrest.
The presence or absence of pulse is NOT areliable determinant of cardiac arrest.
Other determinants of cardiac arrest areunresponsiveness, gasping not breathingnormally, and without any signs of life.
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1b) INITIAL MANAGEMENT OF COLLAPSE
One should always ensure the safety of rescuer(s) andchild at the onset.
The initial assessment is to check for responsiveness ofthe child.
If the child is noted to be unresponsive, one shouldproceed to open the airway (head tilt chin lift). Check for breathing: Look, Listen and Feel for 10
seconds. Note that gasping is NOT breathing.
Check for pulse within 10 seconds (for health careprovider only) commence cardio-pulmonaryresuscitation (CPR) if there is cardiac arrest.
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Chest compression should be commencedbefore giving initial 2 rescue breaths.
If there is only a single rescuer, call forhelp only after 2 minutes of resuscitation.
If an automated external defibrillator (AED)is available, one should check for
shockable rhythm and intervene. (see
below)
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1c) COMPRESSION-VENTILATION RATIO
IN BASIC PAEDIATRIC LIFE SUPPORT
Layperson/Healthcare providers perform 30compressions followed by 2 ventilations (30:2)for single rescuer.
If second rescuer is available, the 1st rescuerperforms compressions and the 2nd rescuerperforms ventilations. Rotate the compressorrole every 2 minutes. The switch should takeless than 5 sec.
General rescuers who are unable or unwilling toprovide mouth-to-mouth ventilation areencouraged to perform at leastcompression-only CPR
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1d) CHEST COMPRESSION TECHNIQUE
For infants, use the two-finger technique for single rescuer and thethumb-encircling technique for two or more healthcare provider rescuers. For children, use the one- or two-hand technique. Achieve a compression of at least 1/3 of the antero-posterior chest diameter
in all children over the lower half of sternum (i.e. approximately 4 cm in
infants & 5 cm in children)
PUSH HARD-PUSH FAST at a compression rate of 100 per minute. There must be complete chest recoil after each compression. There must be minimal interruptions (less than 5 seconds) to minimise no-
flow time
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Two-finger chest compression
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Thumb encircling Technique
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One-/Two-Hand Chest Compression Technique
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1e) VENTILATORY RATES
Following return of spontaneouscirculation (ROSC) and with cessation of
CPR, continue ventilation, aiming to
achieve 12 (for > 8 yrs old) to 20 (for 1-8yrs old) breaths per minute.
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1f) AUTOMATED EXTERNAL
DEFIBRILLATORS (AEDs)
AEDs can be used for children aged 1 year andabove.
These AEDs should preferably be capable ofidentifying arrhythmias in children accurately; in
particular they are extremely unlikely to advise ashock inappropriately.
Those aged 1 to 8 years old should preferablybe used with paediatric pads or software whichtypically attenuates the output of the machine to50 to 75 joules (recommended for children 1 to 8years old).
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If an unattenuated shock or manuallyadjustable machine is not available, anunmodified adult AED may be used inchildren more than 1 year old .
For patients less than 1 year old, theincidence of shockable rhythms in infantsis very low except when they suffer fromcardiac disease. In these cases the risk/benefit ratio may be favourable and use ofan AED (preferably with dose attenuator)
should be considered.
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1g) FOREIGN BODY AIRWAY OBSTRUCTION
(FBAO)
There are no major changes to the managementof paediatric FBAO treatment.
Infants should have chest thrusts to helpdislodge the FB. Infants should NEVER be given
abdominal thrusts (Heimlich manoeuvre) forFBAO care.
Children aged 1 year and above may be givenabdominal thrusts (Heimlich manoeuvre) forFBAO care. Those given abdominal thrusts
should be examined subsequently by adoctor for possible abdominal injury.
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2) ADVANCED PAEDIATRIC RESUSCITATION /
MANAGEMENT BY HEALTHCARE
WORKERS
2a) INITIAL MANAGEMENT OF COLLAPSE
Pulse check (if done) should not take morethan 10 seconds.
Pulse should be assessed at the brachial(for infants); femoral for infants & children)
and carotid (for children).
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2b) NEONATAL VERSUS INFANT
RESUSCITATION
Newborns who require CPR in the nurseryor NICU should be managed as for anewborn in the delivery room. (ie 3:1 chest
compression to ventilation ratio).
Newborns in other settings (eg pre-hospital, ED, PICU) should be
resuscitated according to the infantguidelines. (ie 30:2 if non-intubated)
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2c) COMPRESSION-VENTILATION RATES IN
PAEDIATRICS (HEALTHCARE WORKERS)
NOT INTUBATED
Layperson/Healthcare providers perform 30 compressionsfollowed by 2 ventilations (30:2) for single rescuer.
If second rescuer is available, 1st rescuer performs compressionsand 2nd rescuer performs ventilations. Rotate the compressor roleevery 2 minutes. The switch should take less than 5 seconds.
General rescuers who are unable or unwilling to provide mouth-to-mouth ventilation are encouraged to perform at least compression-only CPR.
INTUBATED
After intubation, compression rates should be at between at least100 to 120 compressions per minute with 8 to 10 asynchronousventilatory breaths.
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2d) OXYGEN CONCENTRATION IN
PAEDIATRIC RESUSCITATION
Ventilate with 100% oxygen during activeCPR.
Once resuscitated (with return ofspontaneous circulation), oxygenconcentration should be judiciously titrated
and lowered to the lowest minimum
required by that child while maintaining a
SpO2 of between 94% to 98%.
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2e) USE OF CUFFED VERSUS
UNCUFFED ETT
Except for newborns, infants and childrenmay be intubated with cuffed ETTs.
Indications for use of cuffed ETTs in non-neonatal patients less than 8 years oldinclude when lung compliance is poor;
airway resistance is high; or if there is a
large air leak from the glottis.
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UNCUFFED CUFFED
NEONATES (PREMATURE) Gestational Age inweeks / 10
NOT USED
NEONATES (FULL TERM) 3.5 NOT USEDINFANTS 3.5 to 4.0 3.0 to 3.5CHILD (1-2 YEARS OLD) 4.0 to 4.5 3.5 to 4.0CHILD (2 YEARS AND
ABOVE)AGE (yrs)/4 + 4 AGE (yrs)/4 +
3.5
The recommended size of ETTs
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2f) DEFIBRILLATION
Patients with ventricular fibrillation (VF) andpulseless ventricular tachycardia (VT) should be
defibrillated
The defibrillation doses in paediatrics should be4 J/ kg for the first and every subsequent shock,
followed each by 1-2 minutes of CPR..
Biphasic defibrillators are preferable as they areassociated with less post-shock myocardial
dysfunction.
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Adrenaline should be given after the 3rd shock andevery alternate shock
Amiodarone should be given (after the 3rd and 5thshock) along with adrenaline
The defibrillation pads can either be placed antero-laterally (1 pad on the right and 1 on the left axilla) orantero-posteriorly (1 pad on the left chest anteriorly and
1 posteriorly at the left scapula) Rule out and manage the correctable Hs (hypoxia;hypovolaemia; hypo- hyperkalaemia/metabolic;hypothermia, hypoglycaemia) and Ts (tensionpneumothorax; toxins/therapeutic disturbances;tamponade cardiac; thromboembolism-coronary or
pulmonary)
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Use and Role of AEDs in Infants / Children
AED has been recommended for use in children
between 1 year old to 8 years old
The AED should be one that recognises paediatric
shockable rhythms. Ideally, the correct AED with
paediatric attenuator should be used.
The dose attenuator will decrease the delivered
energy to a lower dose more suitable for a child
aged 1 to 8 years old (ie 50J-75J).
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AED in Infants
For infants with VF/pulseless VT the optimal dosefor defibrillation has not been established.Animal studies suggest that the youngmyocardium may be able to tolerate high dosesof energy.
AHA recommends the prefer method of shockdelivery for infants with a shockable rhythm inthe following order :
1. Manual defibrillator 2. AED with dose attenuator 3. AED without dose attenuator
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2g) INTRAVASCULAR ACCESS / IO
Bone marrow samples can be used forcross match; chemical analysis; and blood
gas measurements.
Samples can damage autoanalysers andthese samples should preferably be used
in cartridge analysers instead.
The benefits of semi-automated IOdevices remain to be seen.
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3) NEONATAL LIFE SUPPORT &
RESUSCITATION3a) INITIAL ASSESSMENT & INTERVENTION
Heart rate should remain the vital sign by which to judgethe need for and efficacy for resuscitation. The mostaccurate way of assessing the heart rate is byauscultation of the praecordium. Palpation of theumbilical pulse can also be used to provide a rapidestimate of the pulse.
Heart rate should be reassessed every 30s in a babywho needs resuscitation.
If baby appears blue, it is recommendedto check oxygenation with a pulse oximeter
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Acceptable pre-ductal SpO2
1 min 60-65%
2 min 65-70%
3 min 70-75%4 min 75-80%
5 min 80-85%
10 min 85-95%
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3b) AIR/OXYGEN FOR RESUSCITATION
Term babies:
For term babies receiving resuscitation at birth with positivepressure ventilation, it is recommended to begin with air as opposedto 100% oxygen.
If despite effective ventilation there is no increase in heart rate oroxygenation (preferably guided by oximetry), use of higher oxygenconcentration should be considered until recovery of a normal heartrate.
Preterm:
For babies less than 32 weeks, it is recommended that blendedoxygen be given judiciously guided by oximetry. If blended oxygen is not available, resuscitation may beinitiated using what is available.
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3c) DELAY IN CORD CLAMPING FOR THOSE
WHO DO NOT REQUIRE RESUSCITATION
For uncompromised babies, there may bebenefits in delaying the clamping of the
umbilical cord for at least 1 minute from
the complete delivery of the infant. There is insufficient evidence to
recommend an appropriate time for
clamping the cord in babies who are
severely compromised at birth
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Effects of Delayed Cord Clamping
Term Infants
Improvement in iron status and other haematological indicesover the next 3 to 6 months Greater phototherapy need for jaundice ( no well controlled
analysis available)
PreTerm Infants
Reduced blood transfusion in the immediate postnatal and ensuingweeks for preterm babies
Reduced incidence of intraventricular haemorrhage Increased incidence of jaundice and use of phototherapy but no
reports of increase exchange transfusion
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3d) ASPIRATION OF MECONIUM
Intrapartum oropharyngeal suctioning ofthe infant born through meconium stained
amniotic fluid is no longer recommended
For the non-vigorous infant born throughmeconium, there is no change in current
practice of direct oropharyngeal and
tracheal suctioning
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3e) TEMPERATURE MANAGEMENT FOR
PRETERM BABIES
Preterm babies less than 28 weeks should becompletely covered in a food-grade plastic wrapor bag up to their necks, without drying,immediately after birth.
They should then be nursed under a radiantwarmer and stabilized. They should remainwrapped until their temperature has beenchecked.
It is recommended that delivery roomtemperature be maintained at least26 degrees Celsius
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3f) VENTILATION
There is no difference between longer or shorter inflationbreaths
Positive end expiratory pressure (PEEP) may beconsidered in preterm infants who present withrespiratory distress
Spontaneously breathing preterm infants who haverespiratory distress may be supported with CPAP(continuous positive airway pressure) or intubation andventilation. The most appropriate choice may be guidedby local expertise and preferences.
As for ventilation devices, there is yet no clinicalevidence that compares T-piece withflow-inflating bags or self-inflating bags
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3g) CPR FOR NEW BORN
CPR for newborns remains as 3:1(compression to ventilation) ratio.
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3h) CONFIRMATION OF PLACEMENT OF
ETT
A prompt increase in heart rate is the bestindicator that the tube is in the trachea and
providing effective ventilation.
Detection of exhaled carbon dioxide, inaddition to clinical assessment, can be
used to confirm ETT placement.
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3i) VOLUME EXPANSION
Early volume replacement with crystalloid or redcells is indicated for babies with blood loss who
are not responding to resuscitation. Give a bolus
of 10 mls/kg initially. This may be repeated if
successful.
There is insufficient evidence to support routineuse of volume administration in the infant with no
blood loss who is refractory to ventilation, chest
compression, and epinephrine.
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3j) ROUTE & DOSE OF ADRENALINE
Adrenaline via the intravenous route is preferred. Thedose of IV adrenaline used remains 0.01 to 0.03mg/kg.
For intravenous route, there is no evidence to suggestthat a higher dose is better.
Limited case reports suggest higher dose of adrenalineshould be used if administered through the ETT. If IVroute is not available, ETT adrenaline may be consideredat a dose 0.05 to 0.1mg/kg.
In neonates/newborn, the concentration of adrenaline forboth intravenous and endotracheal route should be1:10,000.
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3k) POST RESUSCITATION CARE
Glucose Control
Hypoglycaemia is associated with poorneurological outcome.
Glucose should be monitored afterresuscitation.
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3k) POST RESUSCITATION CARE
Therapeutic Hypothermia For Moderate
Or Severe Hypoxic Ischaemic
Encephalopathy (HIE)
Term or near term newborn babies withmoderate to severe HIE should be offered
therapeutic hypothermia.
(33.5 to 34.5 degrees Celsius).
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3l) WITH-HOLDING RESUSCITATION/
NON-INITIATION OF RESUSCITATION
Where gestation, birth weight and/or congenitalanomalies are associated with almost certaindeath and unacceptably high morbidity is likelyamong the rare survivors, resuscitation is not
indicated. This will include the following - extreme
prematurity (gestational age less than 23 weeks&/or birth weight less than 400 g), anomaliessuch as anencephaly; and confirmed
Trisomy 13.
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3m) DISCONTINUATION OF
RESUSCITATION
If there is no return of heart rate after 10minutes, evidence suggests that the newly
born is likely to suffer from severe
neurological impairment or death. Hence, it is suggested that if there is no
return of heart rate after 10 minutes of
adequate resuscitation, it is acceptable to
discontinue resuscitation.
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??QUESTIONS??