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    Oral Pathology

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    Definitions of the

    following words:v Pericoronal, Periapical, Non-Periapical/Non-Pericoronal

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    v PERICORONAL: lucency aroundcrown of impacted tooth

    v PERIAPICAL: lucency where rests of

    dental lamina expectedv (bottom 1/5 of root)

    v NON-PERIAPICAL/NON-PERICORONAL: lucency not

    associated w/ impacted tooth; area

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    Bone pathology of

    Inflammatory Origin

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    v Apical Periodontal Cyst: Lucency @ apex ofpotentially non-vital tooth

    v Residual apical perio cyst (in previous extractionsite)

    v Lateral Radicular Cyst/l inflamed rest of Mal. Onside of root

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    Periapical Granulomav Lucency adjacent to apex of potentially non-vitaltooth

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    Periapical Abscessv Radiolucency adjacent to apex of potentially non-vital tooth

    vPain to percussion + Sinus tract MUST BEPRESENT

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    Fibrous Scarv Persistent Lucency from fibrous repair in areawhere cortical plate has been lost; associatedwith endo tooth or extraction site.

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    Osteomyelitisv Lucency with ill-defined lucency and w/ or w/oradiopacities

    v Associated w/ percussion sensitivity

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    v Apical Periodontal Cyst

    v Periapical Granuloma

    v Periapical Abscess

    v Fibrous Scar

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    Non-Odontogenic

    Developmental Cysts

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    Stafne Defect:submandibular gland;common lucency at angleof the mandible; not

    intraosseous.Median Palatal Cyst: raremidline lucency; posterior todentitionl clinical swelling ofpalate posterior to rugae.

    Sublingual Defect: uncommon

    apical to mand cuspidStafne

    Nasopalatine duct cyst:lucency of midlinemandible

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    Non-OdontogenicDevelopmental Cysts:

    Nasopalatine Duct Cyst

    Median Palatal CystStafne DefectSublingual Gland defect

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    Odontogenic Cysts &

    Tumors

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    Apical Perio Cyst, Lateral Radicular, ResidualCyst

    Lateral Perio Cyst: lucency not associatedwith impacted tooth; no relationship to PDL.Teeth may or may not be present

    Variants:-Glandular odontogenic: clusters of mucouscells.

    -Botryoid cyst: polycystic; looks like grapecluster (in gross appearance)

    Dentigerous Cyst: lucencyassociated w/ impacted tooth

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    Primordial Cystv Lucency which arises in site where expectedtooth did not develop

    v Almost all are ODONTOGENIC KERATOCYTS(OKCs)

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    Odontogenic Cysts &

    Tumorsv Apical Periodontal Cysts, Residual, LateralRadicular Cysts

    v Dentigerous Cyst

    v Lateral Periodonal Cyst

    v Primordial Cyst

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    Odontogenic Lesions of

    Epithelial Origin

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    Ameloblastomav Any Jaw; Any Age; Posterior or Anteriorv (ALWAYS INCLUDE THIS IN DIFFERENTIAL

    FOR RADIOLUCENCY)

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    Odontogenic

    Keratocystv Any jaw; any age; posterior or anterior

    v Multiple OKCs associated with Gorlin Syndrome(Nevoid Basal Cell Carcinoma)

    v Associated symptoms: multiple basal cell

    carcinomas, OKCs, palmar pits, calcified falx,enlarged head circumference, rib anomalies

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    Calcifying Epithelial

    Odontogenic TumorCEOT (Pindborg Tumor)v Wide Age Range; Majority in Adults with avgage of 40 yo.

    v 90% posterior region (premolars/molars)

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    Squamous Cell

    Carcinoma Associatedw/ impacted toothv Pericoronal radiolucency in patient olderthan 50 yo.

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    Squamous OdontogenicTumor:Too rare to include indifferential

    Clear Cell OdontogenicTumor:Too rare to include in

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    Odontogenic Lesions of

    Epithelial Originv Ameloblastoma

    v Odontogenic Keratocyst (OKC)

    v Calcifying Epithelial Odontogenic Cyst (CEOT;Pindborg)

    v Squamous Cell Carcinoma associated w/impacted tooth

    v Squamous Odontogenic Tumor (SOT)

    v Clear Cell Odontogenic Carcinoma

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    Odontogenic Lesions of

    Epithelial Origin w/ectomesenchyme

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    Ameloblastic Fibromav Very Rare in Adults; usually first twodecades of life

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    Ameloblastic Fibro-

    Odontomav Very rare in adults; majority first twodecades of life

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    Adenomatoid

    Odontogenic Tumor(AOT)v Most in people age 15-25v Extremely rare in molar region

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    Calcifying Odontogenic

    Cyst- Gorlin Cystv Any jaw; any age; posterior/anterior

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    3/4/12 Complex Odontoma: 90 % radiopaque; bag of multiple toothlets

    Compound Odontoma: 90 % radiopaque; single radiopacity w/ radiolucent rim

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    Odontogenic Lesions of

    Epithelial Origin w/ectomesenchymev Ameloblastic Fibromav Ameloblastic Fibro-Odontoma (AFO)

    v Adenomatoid Odontogenic Tumor (AOT)

    v Calcifying Odontogenic Cyst (Gorlin Cyst)

    v Odontoma

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    Odontogenic Lesions of

    Ectomesenchymalorigin

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    Odontogenic Fibromav Can be pericoronal or located in alveolar ridge inany area where dental lamina is expected.Pericoronal lesion must be much larger than theexpected follicle

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    Odontogenic Myxomav Pericoronal or located in alveolarridge anywhere dental lamina is

    expected; pericoronal lesionmust be much larger thanexpected follicle

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    Odontogenic Lesions of

    EctomesenchymalOriginv Odontogenic Fibromav Odontogenic Myxoma

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    Fibro-Osseous Lesions

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    Central Ossifying

    Fibromav Single lucency that may or may not containradiopacities

    v Can be 90% radiopaque with think radiolucent

    line

    v usually this pattern is in old lesions

    v Lesions tend to hang together and come out inone piece

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    Fibro-Osseous Lesionsv Central Ossifying Fibromav Cementoblastoma

    v Cemento-osseous dysplasia (OsseousDysplasia)

    v Periapical cemento-osseous dysplasia

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    Miscellaneous Lesion

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    Simple/Traumatic Bone

    CystMany are kids with mandibularprominence; any jaw; any age;posterior/anterior

    Classically scallops between teeth

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    Central Giant Cell

    granulomav Many in anterior regions but can be any jaw; anyage; ant or post

    v RULE OUT OTHER DISEASES:

    v CHERUBISM: kids w/ bilateral multilocular lesionsof poster mandible

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    v Hemangioma

    Aneurysmal bone cyst

    AV Malformation

    DONT FORGET TO ASPIRATEYOUR BIOPSY:

    COULD BE VASCULARLESION

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    Osteosarcoma: ill defined lucent, mixed/radiopaque; any age/location usually

    early 30s

    Chondrosarcoma: ill defined lucent, mixed or radiopaque; wide age

    Metastatic Cancer to the oral

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    Metastatic Cancer to the oralcavity

    Resembles Pyogenic GranulomaorPeripheral Giant Cell Granuloma

    Ill defined lucent, mixed orradiopaque

    Most in older adults.

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