no. 437 price: university poona - north …apps.nmu.ac.in/oldsyllabi/syllabi/1988-89 u.of.poona...
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No. 437University of
Price:
PoonaSyllabi for tbe Three-Year Integrated B.Se.
DegreeCourse "85 Pattern"( Non-Semester)t,r)Third Ye,,,, B.Se. '
CHEMiSTRY
(From June, 1988 )
-A,
The T.Y.B.S., Chemislry olass shall have six theory papenand three practical course,. Out of six theory papers the follow-ing five papers shall be compul«ll)',
L Paper V -Physical Chemi'try2. PaperV( -Inorganic Chemistry3. Paper VI! -"Organic Chemi,try4. PaperVIJ[ --':Anal}ticalChemistry OR "C"-Compo-
nent for restructuring5. Paper IX -Industrial Chemistry6. The slUdents shall ,eleel anyone of the following Option~l
papers.Paper X -Petrwhtmicals and Polymers
-Nuclear and Environment,,1Chemi,!ry
C -Fundamental. of Biocl!erni'tryandMolecular lliolog) and Drugs andPharmaceutical.
D -Introduction to Bi(>C~~mistryandMolecular Biology
E -Ag.rjcullur~and Dairy ChemistryThe collegemay imp3rt imtructiod in one Or more Optional
papers depmding on their re,ouroc, a!1de~perll",.
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,Practicals :_ There ,hall be three praclical co~r~o:oas follow",Chemlmy (I) Physical Chemimy P,actioals,
(2) lno~;c ChemiSlT~Practical"(3) Organic Ch.~mimy Practical •.
The final Unh/..-s;l} exam;nali<)Tl fo.r each of tho three practical •course, will be of $ix hour". duration.
(Total TY.B.Se. PtWEical e""mi""lioll, : 18 hours). ...,Th. l[LIantlties of ,"4riQU' Chemicals used in all practical W\,.."
;ncll.lding final examination.> ,hould be r.duced to the minimumoomidering the spiralling COGIofcluHnioak
P•••• r V : PIoJ.i<al C1WII,;.try
SECTION I
l. Ku.elics oj homogenea", ret",r;"",,:-M••••'utemell,l of reacl;oo ral" Qrdllr and mQl<;<;UlarilY of
""'Clio,,", fim order reaction' ud th.eir .xamplc •••• cooo order,,",,,,li,,n. and their eumpit'; p8fl&(\omol"""lar <Melion' .• lfeet oftemperature on !'<If,ctioovelocity. the eneTiY of ;JClivlltiol\. (12)
(Ref. l_ChaplorS 13.p~ No. 545-564,571_574.)2. Piwrocl1£mi,l/'r:
The Gr<.>lthUII~Draperlaw. lhe Ein&ldn law of ph()tQO!Jemicalequivalence, Con"'qu"nce, of lighl ahsorpli()l\ by Mlom~ Conse-quence, of h&hI ~b.orptioIl by m<;>l"""l"o.""perjment~l ~tudy of j
pbotoch"mica1 re::r.<:l.iQm,Photochemical 1Il1" ,eaelion', Ph.("sensitized gas re.cti()u,. ( lu)
(Ref. I-Chapter t9. Pa;t' No. 775-781, 784_189.)3. 1~.e.l/i",liV1<0/ Mole",I", $rruClure:-
The molar refraolion, olCClri<;a1I"'larizatiou of molecule"p<>rm,aJWI!dil"'''' moment., deleon, •••!ion of dipole momenl',molecular structure and dipole Illomem" molecular spectra.rotation, Spc<;tfil, microware sptCtrosoopy, vihration-rotationspeOtra, clectnm;c. 6pe<:t,., Raman spectra. ( 14 )
(Ref. I, Chl'l{lter 16, Pai~ No. 691-711. )
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,4. Cry.ral SrrocIUTi!:_
Crystallography, properties of crystals, polymorphism, thestructure "r crystals, Laue method Bragg method of ~ryslal.unaly,i,. X-ray analysis of sodium chloride, Position' of Na+
,j, .nd Cl ion, in lalli"". Calculationof' d' and 'A " ( 12)(Ref. J, Chapt"t 2, Page No. 67 to 85.,,r ,
SECTION II
L Solution.,_
Vapour presSUT.of ideal wlntiorn, Vapour pre,mre of nOlualliquid pair<, BoiHngpoint diagram. of miscible binary mix"Distillation of hi"",y miscible soluti(lM, Azootropes., fractionatingrolumn<. S(>!u1:>ilityof partially miscible liquid pairs, Vapourpr•• ,uro and dJstillation. of immiscible liquid'!, the NerO'l distri-hution Jaw. ( 10)
(Ref. I, Chapter 8, Page No. 272_286. 288-291, 294-296 and298_302. )
2. Electrolylic ConduC/aIlce:_
Electrolytic conduetol\C(', D.t~rmination of e<>nduclance;Variati()ll of condll<;\anoowith concenlrallon, Equlvaltnt conduc-lances at infinite dilnti<>n, Effect of olher fa<:torsOll conduclance,
'.8 ,y'>licatioll of conductance measurC1llWls, Activity end activity. cL".,iclenl, of streng eleelrol}tes, Deferminallon of aClivity• coefficlen!s. ( 10).~ (Ref. I, Chapter II, Page No 414-424,431-438 )
3 Electrochemical cell .• :_
Reversible and i=verslble oclts, EMF lind lIs measuremenl.Standard cells, Cell reaclion and EMF, Convenlion regarding signof EMF, Single electrode polentlals, calculation of single electrodepolemlals, Calculation of cell EMF, Thermodynamics and EMF,Thermodyn:unlcs of eleclrode pOlellHals, Standard potentlal$ and
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•equllibrium con"",,!, CIa"ilh;"tion of clcelrod", Elec!r<>e!lemioal""II, r Classification onll'. )
Po!on(iomctric detcrmiution of PH, Potenliom-,uic titra!ion,.( 16)
(Ref.!. Chapter 12, Page No 471--497,514-520.)
4. Nuclear Chemi.try:-
( a) Di",ov~ry "f r~dioac!iv;ty, The Curies, Radioactive decayand gTowlh, Early characterization of Ihe rays.
t Rd. 3, Page No. I 10 1.)
( b ) Composition of nuclei, Nudear prope'lic&-!Iiooing energy.(Ref. 3, Page No. 19_25.)
( c) Type, of radiQactive dewy-Alpha, Beta and Gam" decay.(Rer.2.PageNo~9(4,2.1), P.109(4.6.11.P 117(4.7,1j,
I d) J,fca,urenlCll! of ",dio"ctivity-t1a •• """ j"n ~~Ir.c,i()nmethod, Properlienal counter<, G. M. Coun'er.
(Ref. 3, Page No. 243-245, 247_251.)
(~) -Application, of radio ;'oto(lCs-Typical "pplicatioll> ofr8dioisolOpc< as tra",,", Chemical Investigation-Reaction meoha_nhm and >t,UCIUrcdetermination, Age delcrminaliao, Ag< afminerals and rocks, Ag< nf earlh, «():
(Ref. 2, Pag< Na. 237-242, 260_265. 1
Ref. l-Principlcs af Physical Chemistry, 4th Editian,By S. Maran and Prutton.
Ref. 2-&"",\i.l. of Nuclear Chemistry.By Prar. H. J. A11likar (Willey En'leran Ltd, )
Ref. 3-Nuclcar and Radi""hemi,lry, 3rd Edition,By G, l'riexlander and J. Kenncd).
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PaJl"r VI : foorpnic Cheml,trt '
SECTION I
L Magnetic Properti•• of Chemical Subs/ances:( ••) Importance of magnetism in transition elemeot chemi&try.
((b) Explanation of tho terms-Magnetic momen', magnetic
" ,I susceptiblltty.(c) Types of m~gnetism-Paramagnetism, Diamagneti,m,
Ferromagnetism, Antiferromagnetism, Ferrimagnetism.(d) Corie law, CUri••.....Weise law, Variation of magnetic
susceptibility with temperature.(e) Use of magnetism in the determination of structure of
eomplexes~Guoy method.,If} Spin only formula, Determination ••fnumber of unpaired
electrons in a complex.. (8)(Ref. I.) . ,
2. Co-ordi~alio~Ch<'mi.,try:( ••) Ge~erala"cou~I~Meaning of the tenu, such as co-ordi-
Mt. bond, double salt, compiex salt, chelote, complexa-tion, central atom or. km, ligand, first and second co-ordination sphere, co-ordinati"n number, charge on thecomplex ion, labiie and inert comple~. Nomenclature,Formation constant, Applications of complexes in different
.. fioi,h.C.~(b) Wernec', IIl,ory-Stereoisomerism with co-ordinationnumber six and four, Simple types of isomerism such Mionisation, hydrate, lin]mg. eo-ordimtioll, co-ordinationpo,ition. ligand.
(c) Sidgwick model-{ effective atomic number), limitationofsidgwick model.
(d) Valence bond th~ory--Hybridj'"tion e.nd shape of com-plex, Structure and magnetic moment of complexes,timill'.tion of V. B. Theory. Inner and outer oroitalcomplexes. Electroneutrality principle. Back bonding(multiple oonding in oompioxes.)
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•(e) Crystal field Ihwry-S1lape' of d-Ofbitals, •.ssun'plions
Splitting of d-orbital, in Oh, Td, sq. planer nnd lelra-gonal ligand, field strong field and weak field compbc>(Ch and Td). C.F.S.E" Evidenceof CF.S.E. magneticpn>J"',lie, 'ptelra, faclors .ffc-clUlgmagnitude of 10 Gdlahn TeUer distortion, Spectrochemical, 'cries Effect of"bonding Onoomplc~e.. ' )
(fl M. O. The(Jryof or:wJredralcompleus- ~Cll:tr,.,ltansfer ••peelra,comparisonof thetheork.. (32)(Ref. 2.)
3. Trall$jlionmelol chemLmy:Chomi,try of Iron Cobalt and Nickel group'.(a) Iron group_Oxidation .tal., soneral properties. O.,ides
Iron oomJl<>unds,extraction(b) Cobalt groupo-Oxidation state~. ge1leT1l1properties.
oompound. containing variable valency ,tale. ,u~h t 1+-2. ~3 and t4 ,(ate,. OCC\ITro:noeand t"traotion,
Ie) Nickel group-oxldatlon stat •• , general properties, COJU_p<Jund~contam.i!18valency states a. -1, 0, -'-1, .~2 onlyand e.rraetion.
(d) Horizontal compari,o"s in the Fe, Co, Ni group'. (8)(Ref. 3.)
SECTION II
,. Molecular Qrhilallh'Qry '.( a) Differ<mcebetween atomic o,hI lal and moJecular orbital.
Comparison of V. B. theory and M.a. tbeory.(b) LC.AO.- .M.O. Principle. Formalion of banding. non_
booding and antibonding molecular ",bital •.(c) Molecular orbital energy level diagram.(J) Molecular orbital clOOlrOn""nfig~ratjon.(e) Homonuclear di.tomic molecule. of "«l tOl" and second
toW demonts.
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,(f) HeterollUdeat diatomio molecule,_Hel, co; NO.(g) Heletonuolea, polyatCll't'l,k 1l1.oleculc1-N01,COl'(h) Muliiocnter bonding in dectron deficient mQlOOUles.(12)
(Ref. 4.)2, Chrmislry ~rrMin group d,rnml" :
C'Chern!,l,y of lli,mp V (N ,Bi) and VI (O PQ).'. ,• .Jlron "f the clements in poriodio lable, Electronic configuration
of Ihe element<, oxurrenoc and isolation of the elements,Trend. in properlie, of the eienlCn(, Wilb respect 10 the followingpoint. :
Si:m. of atoms aJld ion" Ionisation potential" E1ectronegati-vily, Oxidation Slale" and Reactivity.
Properties, bonding and shapes of oxidtl, halides and bj'dridesof theseclementi, (9)(Ref. 3 and 4.)
3. Lamhanides:EleCtron configuration', .;nidation <;tates,I'nthanide cOJltra\O-
lion, occurrcnet, "'paralion of lantbanidcs by ion excbangc and,olvent extraction metbod" npplicatiolls, (4)
(Ref. 1.)4. Aclinld~.-"
Electron conllguratiom, Oxidation ,tntes, General method! of•• [-~ra!iOn of tramurnnic elem~nts, Nude,u fuel" Metallurgy of
~rlUm, (4),(Ref. I.)
5. Corrosion ond paS5;';I)':Corrosion, Atmo,pheric and [mm,",cd coro,ion, Mecha.
ni,m of corro,ion (ThellTy of corrOSi01\), Factor' influencingcorro,ion. Factor> pertaining 10 the metal, factors pertaining tothe medium, factors p~rtaining to cXlern31infloence., Protectionof metnk Method, pertaining to metal" Method, pertaining tomedium, Methods pertaining to cxtern,ll influencel, Passivity ofmetal" Passivity rheorie,. Electrochemical pns~ivity, (9 )
,6. "",rga~icPolymers:
Ba,;c concept and definitions, c1a"iftealion of polymer"Organic and l!\Organic polymers, comparative ,tudy.
Clas,ification of Inorganic polymers, Homoatomic polymer.'''en a" p"lyme •• con'aining boron, silicon. pho'pilorus, sulphur,Flu(>rocarbo1... HeteroMomic polymer. such a, ,ilicon" pilo,-phonitrito compounds, PO", (>~Iym.r" 8o,,,ro1. an-:! its d.rivalj' )
(6) •(Ref. 6.)
Reference Books :N.B. :-Relevant page> from the following books are 10 be
(,eferred.1 ) Advanced Im>rganicChemi.try-Colton and WilkiIlSOIl.
(2) Theoretical Inorganic Chemistry_Day and SeJbin, '''''000&l •.
(3) C<lItci""Inorganic Cll.etnimy-_J. D. Lee, Second Edn.(4) Ba,ic InorganicChemi,try-Cot\oll and Wjj~in'on_(S) Fundamental ConoeP(' of i"e>'ganic Clleuii,try_Gilrealh.(6) Oewlopmon! in (oorgan;c poly,n•• Chomi,try-Lippert alld
Leigh.
Paper VII : Orgallic Chemistry
SECTIOK I
I. Struoture, RMcrivity and Organic T!'cnsformCIi011S(Re"i'iO{)Acid, and bases, Structural effects, Sleric effecls, Resonance
effect, Re"onanoe vc"u, Tautomeri.m, Some con,equence, ofresonance, (3)
(Ref, 1, ChapleT 6, Page No. 196~234.)2. NudeaphUio Substitution at suwraud oar/wn :
The reaction m~'Cha"ism, Stereocbemistry of nucleophilic.ub,lilulion.
The variables in nucieophilic ~ub>tilutio". ( 12)(Ref. I, Chapter 9, Page No. 369-l92.)
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,3. ElirnilUllion Roaeliom': Aiken •• a~" Alkynes ..
The reacdon' mechanism, Stereochemisay. The direct jon ofelimination. (9 )
(Ref, 1, Chapter 10, Page No. 44&-463.)4. Eloclmp6i1ic Additions 10 Unsaturated Carbon' :'rH The mechanism of declrophili" addition, Direction and
" ~lereochemi,lry .oFaddition 10alkene' and alkynes, Hydrogenation,Ozonolysis, ( 10)
( Ref. I, Ch.apter II, Page N(). 5iJO-.'524,530-534. )
5. Suhslitulions at unsatliraud Carbon-Aromatic Compound•.•A(>Olaticily aT\d st~cture of beJ,ze,,,,, Mecllanism and
(lrlentation in elcclrophilic aTomatic' substitution, EiectrophiJicarom"tic substitution rcaction,-H~lero atom' as the e1cctrophiks,Polycyclic aromatic compounds, Reactions of p~tidine.. (14)
(Ref. I, Chapter 13, Page No. 596-602,607-617, 624-642.665_671, 680-684.) ,
SECTION II
I. Nucleophic addilioJ1S 10 Ihe carbonyl I:'oup:,
,Reactivit;' or the "'Irbonyl group, Cyanide a, the nuclcophile-the cyanohydrin read ion" Hydride a, the nlleleophile_redllction,
• ,(~~rboll as the nlidcophile-Orgr.nometaIHc oomponnds, Njtrogen,,' the audiophile. ,( 8)
(Ref. 1, Chapter 7. Page :-10. 241)-249. 257_259, 264-282,285 to 290.)
. 2. Spectro,copy:M3SS 'pectroscopy, Nuclear magnetic resonanee, Inrramed
'pectro,copy, Ultra";okt ond vi,ible spectroscopy, Sp..'Clro'copia$olutions of structural problems. (20)
(Ref. t. Chapter 5, P~g<:No. 130-148, t58-195.Chapt,-r 12. Page:No. 583-589.)
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'" J(6)(ii) Snlphathiawle(iv) Benzocaine(.i) Penicillin,
3. Colo", and chemicol COnS/illi/ion:Rolation botwoencolour und conslitution, wnthosis of :(i) Mothyl Orange(ii) Ph<:nolphthaloin(iii) Congo.red(iv) Cl)';tal Violet(v) Inwgo(vi) Alizarill.(Ref. 2. Volume I, Chapter 31, P~gc No. 868-869.Relevant page. for 'ynthe,j, from chapter 31.)
4. Na/ural Pro<1J;cl,:( a) Introduc(ion to terpenoid, and alkaloids, aenera.melhods
of determining their 'lmOlUles.(Ref, 3, Chapter g, ""ge No. 354-358.
Chapler 14, Page No 596_701.)(b) Struclum, :'\tereocilemi,try anj 'yntho'i, or(i 1 Otrl'll (ill Menthal(iii) Alpha pinene (iv) Atropine( V)Epllednne. ( to)(Ref. 3, Ch~ptet 8, Page No. 361-363, 379-382, 386-390.
Chaptor 14.Page No. 703_105,721_728.)5. Chemotherapy:Illlro<1uclion,Cla"ific.!ion of drug' b~,ed on their action,SYQth",i, and u,es of :(i) P-.acol&mol(iii) lsopropamide(v) Chloramphnicol(Rer. 2, Chapter 18.)Ref, 1. S. H. Pine, J. B. Hendrick,on, D. J. C,'atll and G. S.
Hammon:!,O'glnk C~"mi$try.4th Internltioml E'lition (McGrawHill, I
Ref. 2. !. L Fin", O:g,nic C:"'ni<!rY. Vol. t, si.th Edilion(ELBS J,
Rd. 3. Finl". O;~.nic C.l"Oi,try. Vol. 2. Fifth Edition( ELBS),
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Paper VIII : AulytiuJ Cbemislry
SECTION I
.' (A) Theoretical Basis of QUt11lWali'" IMrga"i~ AM/f,is:
1. Acid h.lle c'l.:Iiiib;ia in w~ter, ,tr~njth, of acid, and blses.,t.iution of p)ly~••;, ~~ids.T;"~ionic P'WYo( of W-I!er, TEte
• hydrog<n ion exponent, "BuIT~r'QI~li<)n. ,( 4)(Pnge NO.7 10 11,25,26,331036.)2, E<piv,tientw_:ig,,(s, norml! <olutions, adv~ntagc' of the'
a,," of eqainlem'J"tcm, 1""pxTlltiou of ,t:mdud <:oh'(!OM, ('.imIrY,tandard SlIb,tanees.' (2)
(Page No. 40, 48 II) S~l3. Neutt4li••tion iridic~lors. prepMltion of indicator solu-
tiom, choire of indic~tors in n~u!.ali'"llion reactions. (4)(Pag~ :-10.5110 57, 70 to 72)4. Elo"lr~jc, potential" c(ln~entration ""II" calculation of
the omf of 3 v<lltaiccoil, (>X;dltio~r~d~clion coli, calculation Mtho,tan1"d p~:eJr'ial, c.~~GJoof the e1ectroj,. p~tential dllring:HIetitr,>tionDrall o~ider](ani a rdu~tant, form~l p~t~ntial., Ootec-lion of the enj ~Int ill o.<ld,tloo r~ductioll,titration. (6)
(Page No. 85!<) 90, ~ to 103)5. CommOll ion effect, ,olubility product, comple~nes' of
• 'preoipitation, Effect CI[ acid~, tem~ra\ure ~1'Jd solv.:lIt upon the\.. :ub:llty of a precipitate. lur."aturalion and predpitate for-mllion, t1l'lpurity <)rth<:p"",ipltate. con;litlom of precipitation,
• warning of the p'cciplta[~, ignition of the precipitate. (8)(Page ;«0. 12 to 17,22,23, IOj [0 Ill, 114to 119)
( B) Experimental teehnique of qU<llllit<lli'. JrIOrg<lnic WIf1Jysis :
I. B1lan-:e WdgiJ~1dnd wigil'ng, O.scription of a typl~alanalylical bJ1anc<:,Tile r"Q.uire;n.'ntof a 8"0:1 b~lall"" Cue anduse "r the b~13n"",m.,!J,.)d,of Wl...;g~ing,ert"" in wdghing, ",Ii-bralion of weights. (8)
(Page No. 14010 142, 144 t" 156)
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2. Volumetric apparatus, Volumetric flasks, Pipelt~, Bure"tleo, calibration of volumetric apparatus, Storage and preservatIonof ,olutioll' for volumetricanalysi,. (8)
(Page No. 19~to 206, 207, 208)3. Precipitation. filtrlUion, fihur papers, fil<erpumps, Goooh
cricible, Crucible filted with permanent porous plate,. Wushini'~l)precipitate" Drying and igllillomof precipitates. (',_
(Pago No. 211 1<>215. 218. to 222)
(C) Errors ;n qUfJllIil4ti,. (/JUl/Y';" :
Accuracy precision mean deviation .• landard d.viatlon.clail$ificationof =or,. minimi:t,atiollof errors, detennination ofthe accuracy of method< of quantitative analysis. (4)
(Page N(l. 11211" 1121)
SECTION lL
(A) Volumetric Wld f""imetric GlUliy.<i".-
J. Preparation of a standard acid and albli, determinationof lhe sodium carbol1lltucontent "fWll,l;hingsoda, determination ofsulphuric acid in the """""'ltrated acid, detetmiJlAtionof a mixtureof carOOn,tc and hydroxide, determination of a mixture of carbo.nate and bicarOOnate. (3 )
(¥••ge No. 233, 239, 24{j to 248. 250, 251 )
2. PJ-eparation of AgN<\. standardisation of AgNO, wI.)lion. determination of chloride, bromide nnd iooide individuallyand in a midur.. (2)
(Page No. 258 to 263 )
3. Preparation and st~ndaTdi,ation of potassium pennanga.nat. and stauda,diSlltioQ of <iel.rmino.tion of iTOn,calcium andhydrogen peroxide. preparation and 'landardi",tioll of polassiumdichromale, and 5tnn<!a,diSl\lionof determination of iron, deter.mination of iron in iron or.. (4)
(Page No, 282-284,287-288, 294_295. 308. 309, 310)
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,._.<. .4. Iodimetry, prcpuration a~d standardisation of sodiumthiosulphate and iodin<:, determination of c<>pperin copper sul-phate, mangan"," dioxide in pytolo,ite, determination of theavailable chlorine in b:cachingpowder, (6)
(Pago No: 343-349, 354_56, 35R, 360-361, 364). S: Gravimetric analy;i,_determin.ti'.,n of chloride as .iii!>"'cr
r'?"':jde";'suIPh~t~as bl~ium Su.lp~late,iron ~s f.rtic ~xidc, alum;-~ l,'''m as alumlnLum 0,,,10:, Calcl1Jrn as- oXlalatc, nickel,,, the
dimethyl glyoximatc. ", ( 6 )(Page ~o. 460--464, 468,-474, 479-480)
( B) Inslrumellial",.,hodi' Of c/lemicl1l, analys.,,"L Color;merry-.Gen~ral. d;',eussion, L:1mbert:s Jaw, Beer's
law, lleer-umber! law, Mol~r extenction coefficieni, appliCOliionofIke", law. D,vi~li(}n from' Beer', law; light fillers, photoelectriccolorimeters. Applieations-<ietermlnation of PH, detcrn,imtionof titanium, chromium and manganese. -( 6)
(Page No. 728-744, 755_760, 778, 779, 789, 792)2. POiemiomelry:-"Brief mention of elect,-odc potential nnd
various tyl"" of clectrodes .,like hydrogen electrode, colomelelectrode, silver-,ilver chloride electrodc, quinbydrone electrodeand glass electrode, Paggend,oiJ compensation method, PH meIers,potentiometric (itrations acid-b,,,,, OKidation J1'dnction and.precipItation. Applications--<!ete,mination of the available chlorine
(.~. bleaching powder, determination. of copper and chromium,
_termination of ferric iron with EDTA. (9)(Page No,921-934, 952-953 and 963)3, . Con<i"C/ometry-Very brief mention ofcondUClance, speci-
fic conductance, equivaleot conductance and eqcivalenl conduc-tallOea1 iofinile dilutIon, conductivity ""11,,cell con,rant, conducti-vity b:idge. Applicot!ons-conduclometrlc titrations acid-base tltra-tions of v.lriou' type" di'placement titratiou', precipitation andcomplc~ formatIon titrations. (4)
(Page No. 969, 972-983)
4. P~""""'y-f'ola..o!r~ph, polariss.ticn of .!eClrodesvoltage CUrrent cha.-cterislic of & mi.".o electrode, supportingelect",!}'te, re.sidwlJ current, limitillt" current, diffusion current,Ilkovic equation poJarogr;<pl!.ic muim., halC wave potentials.ancillary equipn= Cmpola.wgrapit), mercury, dropping IIlIlrcuryelectrode, polarographic cell" maximum suppressors. App!i_cations--<fe.teuninationoChalf wave potentials and concemra.llCJ!l"..,of Cd, Zn an<!Mn ions in KCI 'lliutilln. (L
(Page No. 1000-1010, 1021-1028)
hfrr.lfC.<! :J. A te,t iIoQk of quantitative inorganic anoly,is including
elementary instrumental analysi,_A. I. Vogal. Fourth edition,Th. English Language Book SlIdety.
p&1ltl IX : J_•••.1aI aa..;••.,.SECTION I
i. General A.".., •.• "I h"J""',i,,1 CAe",i3/ry _C1>em;e.tb••h.llry, l!oonomicl (>f cbe""COJprnct •••••• Chemical
prod_ion_Raw ••• t•••ral., Unil Pf'OCM$O',Unit procems, Unitopenlliom, Quality OOOtro!,Process oontrol, Pollution ennlro!.
Chomical process t<clmolo3}'-aa ••iblion or chemical ~aC\ions, Ihtteb .1Id contim",,,. operatio"", ITldustrial c!ternicalreoICtO". Conversion, Seleetivity ~1I<lyield (3)
Z. MllllulaGlure01 Ammo'lia, Nitric acid, PhwpJ",ric ,u:ld and,:)Sulphuric add:(,,) M"nul"c/ure 01 Amm""itl---Modilied Haber-Bosch pro_
ces" Raw material" Proce•• description with f1owsheet,Phy,ico.dI.",iCllI pri""'pl •• inYOlved.Synthelic Ammonia'y".m" Economic,.
( b) M"""lacl",,, "I Nitric Acid--Ammonia oxidation _tbod,Raw matar ••ts, Proce•• d«criplion with lIowsheef. Phy,ic<>-Chemical principl., involved, Conoenll'lliion of mtric acid,EcoJlQmics.
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(c) Mannfaclurc 01 Pho.,ph,,,,'c add-( i) Wet proces,_Rawmalerial., Process description with Bow,!"",!, Phys.ic'O-chemical principl •• involved. ( Ii ) Eleclric furnace procc"-Raw materials, Proce" description with Oowsheet.(iii) Economic and compari,on of W\:t and eleclricfurnace proce5'es.
C(d) Manufaclur. af SulpflUric adJ_O:>ntaot process, Raw
• .} material" Process description with flow sheet. Physico-Chemical prin<:iples Involved, Economics. (8)
3. FmUi:or Industry:(a) G~lI':ral-MlI.ior components ne<:c1sary in ferliliLer',
Clas$ifi<;ation of fcrtilizers, CI8J;&<:sof inQrganic [o.,-tl.liwJ:s,Type' of fertiJi=s pr~ in India, Soorce<ofTnWUU1leri:l\, 'equlred for ma.nufacture of ~lilizers inIndia, Acidity lUId basicity of nitrogen fortiliW'S.
(b) Manufacture of U""", ammonium wttllte, ammoniumsulphate, sup:rpho&phatc, triple IllJperphospbate, ammo-nium phosph\lt~'. and nitrophosphate, with. rcforence tofollowing poin«.
ChemiC.II1reactions. Flo,heet, Process de.>criptionand Eeonomics.
Pollution and its control in ferti1l7.erindu'try. (8)4. E!eclrcchel1llco
,»
5. Sugar Industry:
(a) Sugar and brief sumour)' of DC>n-<:a,bohydrate 'Woolen_jag agents.
( b ) Manufaoture of QIlC sugar-{ i)Culli,'alion aud Harvest"ing of SUgllrca"", (jj) Man~(uClUte of raw C<lnesugar;Raw material" Preliminary ITeatment to sugar elmes,E'traction of juice by m;lling and by diffusion, Purifical;r "\of juice by cla,ificalian Ordefecation process, :Evaporation,Cry'tallisation of surcro,. (caramcUizalion, Sugar boil-ing, M.ssecaitcs) Centrifugation of massecuit •• (mela-•• igc-nic effect, of <.all) Packaging, Flow '''''''t.(iii) R.elining of raw ,ugar , Affm;ation Melting, PLIli.fimtion, Filtration, Cr;'ltaJlisation, Drying, Soreening,Pack'4!ing, Flow,b""l. r iv) Manufacture of direct con-sumption ( plantation.while) 'ugar. FloW3heo(.
(~) OI,r m'l~ing and TIUlnur"ctur< of Kha"Jasari. Flo,",h""'l.( d) Manura~tu", of beel sugar Flow shoct_( <) By p"'duC1< of 'll!l"t inelu,",' anJ thoir uti Ii,,,I ie'Jl(f) Chemical Q{lnlrol and &JUlylic:a1method. : Bri" Pole,
RQrractive indc~, E'limatioo or reducing supr, and lheir'ignificance_
(g) Pollution and it. control in 'ugar indu,try.(h) Sugar indusrri", in India_
6, F"rmcnlali~n Tnd,,,,ry:
Permentation, lmportanl produc1s "r indu,trial fermentation"Ro.ie requiremens of induitriaJ fermental ion proce<~.
Industrial f•.•.mentalion or alcohol frum molJas,e" FacIo,"elfecling producli(lIl (y""st, '!arter, Nuaients, PH, Oxygen,Temperalure, Ume, <1i'lillati()n ele. 1, Plow sheel, Variation inprocr:,sillj other raw malerial~ like whey, Corn, Wheal, Sulphateliquor, Brewing be.r, Win., Spiril'.
Pollution and ils Oontrol in distill •.•.y_
1
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7. SoaPJ and detergent.: _(G) Soap', Function o{soap'ils a cleaning agent; Explain the
terms_hydrophilic, hydrophobic, amphipllthic, micelles, classi.fication of ,oap' and lheir applications. '
Raw materials for 'opa ••.Pat' and oil refining, alkalis andcommon salt, additives and filling m,alOr;ak Soap manufacture :(G I (i) Manufacture of neat .,oap by saponification of oils and(- I,Proce"ing of oils and fa(s, preparation of neal soap by full.boiled (I<cltl"~pro<:.ss)" Half, boild and cold process. flowsheet. (ii) Manufacture <!fneat sOap from fatly adds. (b) Proce'.,ill&of /l<"st,<>apto different soap products like toilet wap, laundrybar soap, laundrichip or Oak. soap, bead ,oap or soap powder.Flow sheet. -
SpcCi)ly""'P produCI'- TransporeJlt wap., superfalted soap',medicated or dwdourant" ,oaps, liquid waps and .hampeo.,shaving soap' and creams, ,rouring soaps alld cleaning powden,Ooating soaps.
a} product, of soap industry-Gly<:e"rine, fetty aoids.(b) Synthdic detergellU (Syndets) vs soaps.E'plain the terms_Surfactant<, Wetting aotion and wettiug
agent •. emulsification and emulsifying agents.Clas.sificat;cn surfactants_Anionic, cationic, non ionic and
ampholytic surfactant •.Syndet compMiticn-Surfactanls, detergenl builders and
additives, bleaching agents, Optical brightness, opaci~ng agent.,¥" "drotropes, soil redeposition prevenling agent., emzymes.\., -~ Synder product, or formulations, Uses of syndet •.
(,) Pollution and its oontrol in soap and syndet indost:y .£Splain the lerms-biosofr, biohard, eutrophic:allon. (8)
SECTION II c'
1. Study 01 Follow;ng Un;' Praeessu ;n Org<S1,;eSynthe.is;A. Nlrral;on arrd Indus/rial producrion nilrolmlzeae;
( a) illtro<\uct;C>lI.(b) Nitn.ting a&<Jlts.
11.:><:.,01 •• 2
(c) Awrnatic nilrotion-Qricntation, Theory of awmatiesub,lilntion, Ortho-para ratio.
(d) Kinetics and moc!lal\i,m "f amrnatic ni!tation.(e) Proce" equipment for teclmical nitrations, Types of
pro<:eS' equipment, Batch nitration, C<>ntinuousnitr~ti"n. •
(I) Industria! prooucliOJlof nitrobenzene-Batcb nitra-tion witb mixed acid Sopel':l,tionand neutralioati \Operating lo"e' in nitmbenzene, Continuous nitra~tion with fortified 'pent acid.
B. Aminati"" by reduction and i"dustrial production of aniline( a) Introduoti"n.( b) Methods of reduction.(,,) Iron and acid reduction.(d) Reacti"n mee!lal\ism.(e) Cheritical and Physical factor,.(f) Equipment.(g) Man"faeture of aniline ( (8)
InduOlrial production "f methanol2, Co"",,,1 irnfuslry-"(,,) D.finiti.:.n and classification.( b) MaDufaetun:of ponland cem.nt-Raw material,. Prepara-
{ion of k~n feeds by dry and wet pmce,', beneJica.,ionofraw materials by ftoatation, burning "perati"n, treatmentof, clinlcr, storage of cement, econ"mic. of p<>rtland •cement manufacture., - )
(oj Cem.nt industry ill l",fia. (6)3. Gla"~Ind;i«ry,-
(a) Glass. Crystal structure and glass structure, Gla••y ,tale.(b) Composition of glJ."'<, Clas"mcation of glasses-,ilica. . &la.s, 96' percent sili"" g!aS«;$, Soda.limo-silica i~$C'
'.lcad'alkaliojiJi•••te gJal,e~, Iloro-silicale gla,,"e•., AlUIllino-.ilicate gla'se'. Special gla"., ouch a' .oolollrtd gla,,',,',()p;tl gla"es, Fibrous gl""""., P!l<>sphat.gla"es, Siiicaf= glass." Opague gla".
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( c) Propertie, of different type' of gI3"".'- Vi,rosily, thermale'P'l",ion, thermal endurance. thermal conductivity,oplical propertie" electrical properties, meehan;",,],trength, chemical durability.
(d) Manufacture or glass-Raw materials and funotions ofglass forming ",ides. Outline of manufacture of -glass,Gla" melting, Gla" formati<m by hand molding andmechanised prod,,",c, like pressing, lowing, drawing,tolling, Annealing and fini'hing.
( e) Glass ",,"'«miematerials-Nature and f<lrmatioll, properHcsand application'
(f) AppU",<tion' of glasses ill different fields-Chemical,lighting and light filter" clcctrical, oplical, thermal.(rnotural elc. (12)
4. CeramicfMuJlry :(Q) Definition, ciassificali{)n, cia"", of refractory materials_( b) Elementary treatment of oollding in 'olids.(,,) B:"ic row malerial, for ceramic prtparation" ceramic
industry, coramic process, outline of process of maltO_faoture of ceramic materials. Manufacture p=sscommonly used in Clemmie materials-Matc .•.ial.and bodyprep<lrar;on, Forming processes (Dry pressing, ext.rusion,forming from ,oft pia,tic masse" sHp c:!Sling), Greenfinishing, Drying of ceramic were, Firing of ceramic ""Ie,G13ze. Enamels, Ceramic'colours,
(d) Cera";ic products-Traditional ceramics fWhitew~struct.urai elay products, refractor; es enamels and 'enam.1Mmetal), '-'Nc'v cernmics. Metal ceramic' and other
,.',- .', Oci'mpo~tes.,...~" , ,Refereno, BookS,.~.'-,',."I ,Principle" of ,IRdu<tTi~l Chemistry-C, '. A. Ciau'en and G,
Mattson, Wiley'lnterscietICc, . ,1'" " '0,1.2 .. 'Roger>' Industrial Cllcmi,tJl'. 'yol" r, 'l.I¥I I~fFurDs,,! Ed.
"p.Van !'1!l<lrand.Co\llpany. .";'. _:;:
•
1,,
"3. 'Chemical ProC!:" Industries '-Norris Shrove, Me.Graw.Hill
Book Company.4. Rie~l's HClldbookof lnotganic Cl1cmistry-James A. Ken!,
Van No.trand Reinhold Company.S. Dryden's outline' of chemical te<:hnology_M. Gop~l.Ia Roo
and ManhalJ Sluing.6, Chemi""l Technillogy-George Koval, Trans1tJ.ledby (Origill41 \
Authon)' MuJkhyonov and others), MIR Publisher<,Mosco.
7. Jnit proc••• in Organic Srnthe,i.-p. n, Groggin'.8. 'lndu'(ri,,1 Chemi,try' Par!, I and JI-R. K Da,9. Element. of Ceramic,-Norlin, Addi!'on_Wesley Publi'hing
Company.
Paper X A (OptiODol) ,
Pell'O<hemlcal. ud PolYJII••.•
SFCTlON I
p.lr(Jc~ml.ab,
1. Po:troleumand its pr<>duct. (Ref. 3, 403--426) (L-6)Disoov<:ry 01 petroleum, petroleum. reserve', nature of petrol<:um.Olla••itication of petroleum, petroleum r~fini"i, de••.lti"ll, diOlilLvlio!l. Cracking pr"""".' iUch a, lhmnal and catalytic cracl;ing_Catalytic reforming, ultraformlng. Lubricating oil, refining )hydrogen processillll of pelrole~m.
2. The sources of pelrole~m hydroCl:rbons (Ref. I, 17-41 ).( L-4 ) Compo,ilion of crude petroleum. ""tural pi, itparatiOJl ofcrude petroleum, paraffin wa.. Other refinery pr<>ocsse•• ~ch •.•thermal cracking. CII!alylicand hydlocrackillg, thermal refmmillg,cctalytic reforming, hydrogen trcati,,!, rJkyl.tion. I,omeri"'lliollIlIId polymerlZl1.tiOll.
3. MlIl:lufaetllre of olefill. (Ref. I, 91_129; Ref. 2, 1-11)(L...jI) PriJlCiples of crlIckllll &Jld J"j'I"ol)'si., traclclllll practice,
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petrole11Ul'(3)
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""paration of ga,"". Iadividual olehn'-ethylene, propylene.butene •. Thermal cracking for otefuls.
4'. Hyilration af olefin. ( Ref. 1, 1'36_145) ("r.:2 )Absorption in sulr~rjc acid, catalytic hydration, ethyl alcohol.5, O"i<htion of olefins (Ref. 2, 61-10) (t4)The pmduction of acel;" add, ethyleno oxide, propyl",," oxide.6: Oioleftns(Ref.2,'J8-39) (L-4) . ,
.~,1 ••.•._.. ~d,. "c"_d- "~.,•..•••......•••••••-.-.....-••-_','7;- ," .. "'" p••••uC ,on 0 lOU••• ,ene. __ __._ ._. _7. Naphlhc""" (Ref. I, 245-259 ) (:Ref. 2, 126_131) (L-5)Routes to naphthcllC', occurrence,' isolation :md '=iOllS,
naphthcne<', lhe manufacture of caproJactam. '8.'.,'Arematie>(Ref, 1,260-298; Ref. 2, 99-125) (1.-10)Benzene, tolll'-'I1eand xylene.; higher aromatics, naphthalene',
Manufacture of stjl'<:ne and route. to phenols. ': ..-'_, 9,."Acctylencs.( ... c_, Ref. 2,;I(l,-49) (t.-2) c
I:' ' .. _., .... ::rru, BASF .,cetylcll<' proce~s., ,','• IO",Petrolewr, <lepos;~ i,n India;, Det""H"n ofdeposits; SlaW' of p«,olcum Indus,ry.
Reference: 'J. The pe.lOleum ch',mi""l, [ndnstry, 3rd Edition, R. F, Gold_
stein and A. 1. Waddam,,: E'.and F. N. Spon (1967),, 2:' PrM:ueiionof "Polymers and ':pi2.stie "li:itermediare, r,o'm
petroleum, R;:'tong, 'BuUetwottl,,-( 19(7).3. Rieger, Handhook of Industr;"-I q,.cmi<try., 7th Edition,. ,',', , " "
J. A Kent,VunNo'tr~nd (1974),' .",.' .". ',~
SECTION IT
•Polymer Cb."",i"c~' ; f'(' ,:r ,-:
J. lniroduction' Polymers Polymer, .iJ4",d ';9d~sl(ie.:-rubb<rplastic:;'fibre, coatingsadhem'cs. (6)."",e't'Rd'. 1-, Gii-lf,tcr 1-) "."C, ,':' ,,-/", ," ''':, ;' i 2, Polymerformallein', Polimciiutioit ~i.lob.~,fnitcII~~lity kinelIe nsch~mcs, crnin polymoriza(ion, stepwise polJ-meri..zation 'Iomd,~ '''''''''diw..tion: OOmplh pc;fyini:¥liatirim, (deUi,iled:m<;chanismand Tate eXlm's<ionnti:!xl ))m1twd, Ij..-"":',".' "i,".' (-,j ,)
( Ref, I, ehc.ple: 4. ) ( .r,:..'.,\ ~:.~:. "';.~..
"3. Polymerization processes: Bulk polymerlution, 001,,11011
l"'lym<:';ZIluo", ~uspemion polymerization, emulsloll polymeri_zation. ( 6 )
(Ref. I, Chapter 5, )4. Molecular ",eight of polymer,; Averace mo!lieula!
weight, mea'"","",""! of rnolttular weight, wmber average, mol.,..cular weigh! method" weight averas", moke,,1a! "''"illt me1hodrr
(,,(Ref. 1 Chapter 6.)5. Carbon chain po!J'l'I"": Polyddlne. ADS lfOllp di_
polymer! Vinyls ac:ryliQlOftucrocaroolU (Deta;~ mlUlllfacturingprocess and lIow oh~t.IO belemitted.) (10)
(Ref. I Chapter 13.)6. Helero <'Ilaizlpolymen: PoIyeoler, Polyethen. Poly
acclIarioleo, polyamide., aldehyde <:<rndcl\'Al.tion poIymcon, poly_100000000ru (~ilod ItIIDufacturing proo••• and ftow .heet to beomitled.
(Ref. 1, Chapter 14.)
Reference :
1. Prindple. of pol~lller system •. F. Rodrigues. TaU!McGrawHill Puhli,hillll ComplUl)' Ltd., New Delhi.
Paper X B ( OptloMl) :
Nudear ••••• Ea.-ll'OllllleaW CIlellllstry;
SEmON INucl.ar Chem/stry'
1. The atomic Duc1OU$: The nuclou. and lb' outer sphere,c1wificalionofnuCIidn,nuclear~tabilitJ. (4)
(Pllgc 3-13)1. Nuclar medeI.: Thulldl model, thloliquid drop model.
the semI empiriea1 mua equation. (6)(Page 52_57 67-13.)
,, 'ii
I
3. Radio'activity: Typesof radIo aetj~ d~cayand dreayschemes general characterislics, d=y kinetics, alpha -decay,h<t~ derny, gIlmma em,lssion, nudur j,omeri5m and isomericIran'ilion, inlernalconversion,the augur effect. (10)
(Page 8~-95. 109_111, 117-124, 137-143.)
4. Nuclear reactions: !lethe's notalion, types of nuclear(fions. . (4)0; (Page 148-151.) 'I:
, 5.: Nuclear fl"ion', The-proce" of nuclear JiS'ion, fissionfragments, 'mass and charge distribution, Ji"ion energy, nuclearreacrior", breedor reactor, nuclear =10'1 in India. ( 8 ), (Page 186-J93,209~211,222~224.)
Nuclear re''''!oTS-Thenatura! "uranium reactor, lhe classl.fication of reactoN, typical reaetors, breed"" reactor, nuclearr~c!or. in India. ",- (4)
(Page 209-211, 216-219, 222-224.)
Applications of radio activity probing by isotopes, typicalr~acfi"ns for tlle preparaf ion ofradio iwt op•• , thc Sli lard-Chalmers.reaction, "idio chemical principles, I~.pical applicalions of ",dioisotopes as tracers, analytical app)icatioDi, .age determinations,me<lica.1upplicMions, agricultural ~pplications, industrial appli-",tions. ". (16)
• . ... :Reference: .' .C'l Essentials of ~udcar Chemis!r~, H: J. Amlkar, Wiley EasternLImited, New Delhi ( 1982). .
•SECTION 11
Environmental Chemistry:
1. Brief discu5'ion of chemical cyoiution and origin of Mc( Ref. I, Pagc 40-60, highlight •. ) ( 2 )
2. Brief discll5sion of fo",il fuels and newly developing.\energy SoUrces. (Ref. I, Page 92-155, highlights. ) ( 4 )
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3. Air aod air pollution (Ref, I, Page 181-253; Ref. 2,Page 7-29 and 67_71.) (14)
(,,) The almosphCTe-5lruclure and properties, temperatureinversion and air pollulion episode" atmospheric photo.ohemimy, possible depletion of slralospheric oxygen, •nalural versus polu!<'dair,
(b) Air polJutiOJl-lnduslry and OIlergyrelatM. Particu~ }maller, analysis and control of particulales, sulfur oxides,effect af sulfuTdioxide, a,nd particulates. OOJItroltechno-loll' for aulfur aside<, other industrial air pollutant •.
( c) Air pollutiOJl_Transport related. Carban monoxide,nitrogen oxide" photochemical smng airborne lead,<><>ntrolof automobile emissiom, alternati,"CSto lhe autocycle enain•.
(d) Mi=lIaneous: Aeros"ls-Caroon dioxide and wall'r,indoor ""liuli"n
4. Wllter lind water pollution, (Ref. I. Pa~ 1~1--412 ) (14)
(a) General principles-Unique physical and chemical pro.pertie, erileric of water Quality, natural water-eulrophi.cation, detergent. lind phosphates.
(b) Municipal wa,te water treatmenl-The iJnportanoe ofmicroorgenisms in waler purification. primary andsecondary treatment, tertiuy or advanced caMe water •trealmont, remo,.•1of nitrogen and phosphorous, dispi )oflJealed waste water in solids. .
(c) InduOlrial waste water-Sources of indu.trial waterpollution. heavymetals, mercury, detection and abatementof mtJeuT) pollution, paper milts. ahaleD,ent of papermiH pollution,
5. Solid wWltes.(Ref. I, Pall" 317-345.) (4)Population, .Illuence and teclltlOlogy, municipal wasles,
rec!aJnltion, reoycling and ,euse_ The entropy ethic and solidwalle.
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6. Life. (Rcf.l,Pagc417-470.) (10)(a) Toxic substances. tipids, det(l~ification of for~jgn-
substances Cfl:<)'meactivation and inhibH;M, molecularmcchnism, of rnulagcnesi" c.1rcinogcne';l a"d telrMo_genesi'rn c13~sjficalionof to(;C substance'. The ivinylchloride ~p'sode_ C"nlrol of toxic sublit'llce in Iheenv;nmm~nt.
(~ (b) The sn,tenance of life. Food qual;!}, the green r~vo_
• } JUlion, p"'t o(mtrol, peni5{cnce of pesticide" toxicity ofpesticides, made of aClion of pesticides, itegraled pestmnnagemenl, energy and agriculture.
R~f~re~Cf:3:(1) Environmental Chemistry I.,W. Moo« and E. A. Moore.
AcademicPw;" N~ York( 1976).(2) Air pollution, D. J. Spedding, Oa,endon P,=, O.ford
(1974).!' Gelleral &jeronce :,'f ChemiJ;try and PoliutioJl, F. R. Benn and C. A. Moanliffe,
McMillan ( 1975 j.
t' Paper X.C (Optional) :
Mol«'tI1ar Biology •••dFulldamclltlll, of BIochemistry RbdDrug' and Pha ••••••• mlcllis.
SECTION IFullllnmem.l. of BJoch.mistry and Mo]""ular Biology:,(\ l. Enzymes,(Chap. 1, 157-160,t68~I80. 184_188.) (6)
2. Biochemical energetics. (Chap. 6, 137_138, 141-152.) (3)J, Metabolism ofCrbohydratcs, Fat', Animoadds.
(Chap. 10,179-294,304_307, 327-336.)(Chap. 13, 3S3~357,359-360, 363-368.)(Chap. 17,462--470.) (10)
4. Vitaminsand oo-enzyrnes.(Chap. 8, 195-197.) (5)StruclUre and Biochemical functions of nilXltinamide,Riboflavin, Lipoic acid, Biotin, Thiamine, Pylido~ine,Folic acid.
(Relevant Page' from Chap_ 8, pp. 198-222.)
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''IJ
5. Nucleic acid,. (Chap. 5, pp. 11l-1I9, 124-132.)6. Bio,ymhc.,;is of Nuc'eic acid.
(Chap. 13, 505_526.)7. Bi"synthesi' of protein', (Chap. 19. 527-555.)
Rejeren('eOutlines of Biocl!emi,try -By E. E. Conn and P. R. Stumpf,4th eddition, Wiley International ( 1976).
SECTION lL
Drugs alld Pharmae •••ticah :I. Geneoal asped' "fmedicinal agent'. Mechanism of action
( Bioavvilability), Drug ",,,irniJnti,,n, di,tribution and eiirnirullion.Ref. I, C1aptel"S 1, 2, 3 aud 4, pp. 11-87.Do",,-To,icity of druS', Drug intcr~cljon.Drug ahuse-Akoh"li,m, P,ychomimatocic agents ami ,df
medication,Rd", 2, Ch>lptcr 6l!. pp, 12fi~ lllOO.
•
,,
I
Sys&emic Dr..,. :A. Drug acting on G.Ll (GastlO l.ntestiJlll;ITract)--
ieneral inlrodu~tion. e;o;amplcsand .t,oeture, of Antacili', Laxa.tive<, Purgatj,-es, Alllluicers. Anti<pa,modic,. Carmi)lll,live'.
Ref. 2, Chapter 40. Page No" 734-756.B. Drug. acting on CNS (CentrMI Ner~ou, Sy'lem)---
Introduction, examples and Slructure>, usc> of Analge,ie" """'1 'pyretics, Tranquili", ..•., and CNS ,timulants. .
Ref. 3, Chaplers 3,~8, 9. 3 (8-14),8 and 9 (32-45.)C. ' Drup ""ting On ANS (Aulonomous Nervous S)',[em )-
Cholinergic and Adrenergic agent>, Anlieh"lincrgie; Alpha andBela bloeke".
Ref. 3, Chapte'" 15, 16. (353-392 l.D, Drug aoling on cardioVll$cular ,ysthem-Cardiotonic-
Cardia! gl)'CO'ide" Antihyperl'en,lve and Anticoagulant,.Ref. 1, ChapleT' 17, 18, (17 (396-426), 18 (432-442). (20)
(18)
,
3. Ch,molh<ropj-Study 'of i1ifferent"gents, Mechanism ofaelion, Structures and u'e' of_
( I ) Antimaler;als (2 rAntibacterials'( 3 ) Antlamoebic (4) .Antifungal'(5) AntiviraL (6) Allticancer
(" (7) Antibiotics (8) Sulphonamide_,.< ' ., ).Ref. J, Chapters 28, 30, 31,33, 34, 36, 37. OR
'Ref. 3, Chapters 26 to 30;'''n, 34, 35. 26 to 30 ( J48_187 ),33 to 35 (196-204.)
Ref<rencesL Principle<of Medicinal Chemi,try_WiJjiam O. Foye.2. Remington', Pharmaceutical Science. (MACK Publl,hing
Coml"'ny, E'ton, Penn,ylvania.) ,3. 'Organ'ie Pharmaceutical Chemistry-Harkin'han Sino:h and
V, K. Kapoor.
Note :-'---.23(Pages 705 «I 710), 32 to 34 (Pages 755~RI6),36 and 37 (Pages 837--S70.)
,I
'~ .Papet X.D (Optional) :
rnlrml"~;ionto BI<>ehemlstryand Molmllar B1olog)
C':. SECTION I 'Biomoleeules: Strudurc and fUllCtional group" Stereo_
i,omerl,m and optical activity. Biochemical activity and phyalo"logicJI ,Ignlficance. •
(a) Amino acid" peptide. aad lheir amphoteric properties,""lour reaction, of a'1'lno acids.
(b) !lase" nucleosldes and nucleotldes, coenzyme'(c) Sugars (aldose. and keloses) mono-, di-, tri_ and
01Igosaccllarid<->;.( d) Lipid" simple lipids, pho'phoJipid, and glycolipid" (10)
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Biopolymers: Primary, secondary, tertiary and quaternary~truclur.s.
(a) PrIJI"ins: Globular prolcins-<,lructuco and function ofmyoglobin and homoglobin. Fibrous proteins.
( b ) Enzymef: Biouaraiys('-<'ITUcturc and function. Kinec.lic' of enIYmc CIl.tal)"lodsingle SUbslr~10irr~•• "iblereaC(iollS.Determination of Km. Vma. and lh., ' ••ignilicance. Simple comp<-1;vcHnd non-001llpetive typeof inbibili<>R. DetcrmiD.:l,lion of Ki. Simple problem. onenzyme kinetics.
(c) Nucleic Acid" Slructure of DNA and RNA (1-,ffi-, r-).
(d) Polysaccharides' Starch, Glyooatn and Cellulmc.Slruolural fea.ture, orbiom~mbrane>;_aoti"e and pa.ssiyetransport of ions and metaboli Ie;; aCT"'" the [>la<mamembrane. 1'151
1•
CeH: Structure of uelJ .nd imraool1ull, (Irgani•• tioll. Com.paratlve 'l~<ly of st,uolure or ""olonal, ani rnal am! plau'. ,dl, '"ob<erved unde, light micro'COpeand eleetron micra,eope. Chemicalba,is af microscopic ,taining. (6 )
Cdl obey the law' of chemistry. Law' af thermodynamic"caneepl of free energy and their applioalion to hiolagic sy'tem,.( Wat,on-Citapter, 2--6.pp. 25-146), Origin of life and ,he Mende-lian view of world. (~ )
ScparatiOll method, used in hi<:>chemical inve'tigation"Principle snd application, :
(a) Eloctropbor~,i •.( b) Centrif "pt ion aDd Ultracca(tifugation.(c) Chrom~ngrap~y ("d~>rp(ja". ionexcbange, p3rlilion,
geifiltclllio" and bioaffinity).(<1) Dialysi, and ultrafiltration.(e) Fra~(ionltion af protein' with ammonium 'ulp~ate and
w~!.c mi'ICibleorganic <olvam,. ( 7)
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"SECTION II".
Bioenergetics and Melllbolio- Pathways-With emphasis onmechanism ,of reactions. uhninger_Parl II (pp. 331-(45). (21)
Some aspect' of Hum:rn BiooiIcmistry, Dige,tion, Transport,].. and the integration of metalboli<rn. HormQn~and vitamins.
Human nitritioll, with special ref'fell"e to Tndianfood preparations( I. lheir nutritive value. Food additives, preservation and
• poison.,"Lehninger-PartI!l(pp.681-735.) (6)The "rrangement of genes' 011chromoS<lm••-struclUre and
fllJ\Otioll.Genetic code and mutation. Mole<ular b.~,j, of repli-calion, lran,oriplioo and lran,lation proces<e<, Structure of viruse,and 'their repliMlion. uhninger_Part IV (P, 791-913), Watson(P. J 49-685)-genernl"mline"r molecularbiology. (21)
THI Books'(1) Principles of Biochemistry-A. L. l.A:hninger,1st Edition,
CBS-Pulblicatioll lind Di<lributors, Delhi_110032 (19M).(2) Moleculllr lliology of the Gone_I. D. Wat,on, 3rd Edition,
W. A. Benjamin, I~C, California, USA.
Paper X : Optional_AgrlrnJlure and DaIry Chem1<try,
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SECTION IA. Agrkultu,e Chemist.),
. Fertilizer.! :-Imp<>rlllnec of fertilizers of classification of( .•..'tilizcrs in crop produ~tion. Chemical principles involved inmanufacture of N,P.K. f~tlilizer', Physico_Chomical propertiesof nitrogen ions, pho'patie fertili,rrs Reaction of N.P.K. rerti .lizers in calcareous and acid soil,. Fertilizers eontalning micro_nuniems, Mod of application of fertilizers, Factors affectingefficacyof rertili""rs. Slowreleasingfertilizers, trificalion inhibitors.Problem associated with storage of fertililen. ( 7)
Mam" •.' :-Farm yard manur., oil cake,agroindLlstrialand urh:mwaster organic recyclingin <oil fertility, biogas plant survey, sewage.
green manuresrole of manures
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Soil Tesang atul Fertilizer use :-Sampling or soils. Testing ofsoil .ample fOTtc"lu~, ,PH, COllduCliv;ty, organic carlxm av~iJableKP.K. Test for lime and Gyp,um requirement, of problem 8Oil.interpretation of $oil, lcst results for fertilizer rewnunon<btion.Soil fertility and factors affecting it, Evaluation of wil fertility. ,Soil, wafer it', expre•• iol\, energy coo""!,t,, wil moisture constants.Teoling irrigation water for PH, CO" HCOJ, CI, SO" Mg, NO",""interpretation of results. ( ••.•- •
Pesticides :-Cia<,ificalion, slrocturo and chemical propertiesof I""lidde, (2)
Fungicides ;--Copper, Sulphcr and mercury e<>mpoun<1s,aIlt;.biot;,.•, bacteriocide,. (2)
Herbicides :-Syotemic" ",loc(;,-c< and IIOmeleclive weedkillers, Roe!enlici<ies, nematocides, Hnrmo~" gJOwlh modifler.cyoocoeI, Gibberllina. formulation of Chemicals, compalibility of.prays Hazard, and safely measures, safe limit of chemica!"",id"",, in food and vegelable (2)
{"",<tidMS: .Synlhetic and planl originated compounds,organic organ ph"'pat •• , orpl\O el1locina!edhydrocarbon. carbo.nal", Ouurid,'" ar>t'""lc" pyrelhrum ~n<Jr~knor.. (2)B. PraCliear..:
(Ea~h practical is oflhr.o hunn;. Out ~f 10.' lea-'l 8 practical'arc to be la1<cn,)
J. Analy,i, "r a.H.c.2. Analysis of Copper Fungi~ide" J3. Delermi"",i"n "f I""lieide rc"<iduc, in Food grain' ml" '
vegelabb,4. An~ly,i, of f"rlilizc(s for moi,l"r, N'ilroge rho,poruu'
and K.5. Analy,i, fur PH, org~nic carben avail~ble N,p,K, in Ferli.
Iizer mixtUl"s.6, Collection uf rcpr~scntalive wii ",mpl •., from fleldoaad
preparalion of soil ,ample in l.botalory.1. Analy,i, rur frre QeO" Lime and Gypsum requi,emenls
uf problem ,oil.,
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''';8.- Anal~js or irrigation water nmi1nterprelalion of result,.9. Preparation of <oil le,t report intc-rpretalion of results
and 'fortili'er recommendations,,(, 'R.jerenee BQoks jor Section I
" (I )'.Agricultuml problem, of India,by P. C. Bansil.(2) Agricuftural problemS' of India by C. B. Momorla.If-) Indian Rural Economy by N. C, J",hi.
• l'...J~,Agrjc\lltuiatde\'elopment of Indian P{lJicyand problems.e<lited by C. H. Shab and C."N, Vakil. ,
(5) Hand 1>ookof Manure, and fertilizers LeAR. Publications.(6) Manures and fertilj,." by Ya""Tk<!r,(7) Soil oonservati<m in India by M.S,V. Rarnarao, Publisher_
Indian Council of AgriC'UlturalResearch, New DeIhL(g) Elements of ,oil conservation' by H. H. Bonnell, Publisher'
Me Graw H.,H. Book Company, New' York ..(9). Introduction to Dyronomy and 'oil water maMgement by
Vaidya and Sahasrabuddhe.(10) Soil management in India by Arakori et 81.
Equipment for Pmelicals fo' Sec/ion 1I :Expt. I :-Burette 50 ml,. Pipette 25 ml., Conicai fla,k 250 mi.bpI. 2 :_BUTOtlC50 ml" Pipelte 25 ml.bpt. 3 :~Burme,. Pipette" Conical flask.Expl. 4 :-Kjelda's fla,k, Burelle, Pipette etc.Expt. 5 :-PH meIer, Fiame photometer .
('.' EXPL6 ,-Butettes, Pipettcs, Conical flask.ctc.E,pt. 7 :-Bun;tte', Pipettes, Conical flask etc.Expl. 8 :_Em;rs Cohimeler.Expt. 9 :-Bnre" •• , Pipettes, Conduclornclof.EXpl. 10 :-Semimicro app.natus,
SECTION IJA, Dairy Cbemi'll")' ('fbMr)') ,
L introduction :-ImPOrlanCe of dairy Cbemistry, Different,constituent, of milk, proleins. Lipids, mineral" enzymes vitamins,'Con>tituents of milk", a!fected bj milk process. (4 )
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2, Composition of Milk :-Compo,jlion of milk f!'OmdHror-ent'sp«:i,,' e.g. cow, 'heep, goat. buffola milk, Facto" affeclingtheoompooitionof m~k. (4)
3. Protein. :_Study of maj(>r. milk protein, and wheyprol(ins Protein classification and nomenclalUle. (4) •
4. Milk Produc", :-Different major milk products. Nu(fiti\-cvalue "f milk and milk ptodllC{'. (4 ~
5. H~rmone. 0",1 other Class•• of Compowuls :-Study ,harmonc., Carbohydrates, millerals, lipids, en~yme,. in relationto mill. Bio'ynthC"isof milk. (8)B. Dairy Chemistry ( Practk.") :
(ElIch practical i, of three bonrs. Oul of len at tta,{ eightpract ;cals are to be conducted. )
). DelcrmiJllltion of .pecific gravity of milk from dilferen!.ou=, by using lactometer and <{l«Jioogravity boUle.
2. Determi•.••tion of fa, content in milk and milk product,like cream ImlteT.
J. Del.-rm;nalion of total calcium and poo.phorou •.4 Dc~rlllinationofc:a.<mnldk,5. Determination of refractive index of &hee.6. Determination saponification value and iodine value.7. E'timation of acidity of milk and milk products.S. Determination of aduUcant, and preseT'at;,," in milk.g, !ktermirullion of PH and total solid, in different milko.10. Samplingof milk and micTo=pic elWllination milk.
Refe,.,,,,. Books for Section l/(I 1 Outline of dairy technology ty Sukumar Dee.(2) Milk and lIIilkproduct by Dampharl.(3) Twing of milk and mIlk prodllct. bi Alherton and
Newland, A.V.T. Publicationo.(4) Fundamental of dairy ,cience by Webb and Jonoon.
!'iole :-Eqllal weightage i. given t" theory and practical. ofrespective secti"JlS (i.e. 5(llIIIIru f"r theory and 50 maTt< forpractical•. ) End examin>tion will be conduct•• imilar to comp"_nent . C' of restructuring ""uroe.
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I
T.Y.B.Se. (Chemistry):
Ph}'sital Chemistry Pracli<ah :
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C.)!I
Gl"OIIpA ( Camptlhary) :I. Kinetics of bydrolysis of an ester (Two ""n""nlratians).
,. 2. Comparisian of relative 5trengtrn of HCI a,n<!H,oS.\ 1Ie kinel;cs of inversion of cane ,agar. '
• ',.3. Kinetics of the decomposition of H,o. by o:<ygenlibera-tioll,method mtalysed by KI.
4. Determination of ;lhe ,onolar refraction of. givencnmpounds-acetone, benzene, chloroform and mroon teltachloride,(Densitie, to be determined by pyknometer.)
5, (a) Determination of )jmax and <ancen!ralion of gi"enooppe. sulphate in ammonia solution by eolorimelr~.
(b) and ,jmax and concentration of KlCrlo, in 0.01N NaoH.
6. D<termination of lhe IrallSition lemperature of sodium,ulpb~te decabydrate/SodiU!" acelaw decabydrate by (,,) thermo.metric mci.hod and (b) dil.tometric method.
7. (,,) Determination of lhe cell con'UlJI! of a given conduo"livit~ cell IUlinS0,01 N KC!.
( b) Determination of!he di"aoiatian C~)staot of a weakntenob3sie acid.
S. (a) Prep"ation of 4 differenl buffers aad checking theirPH potentiometrically. D,lermrnalion of the PH ofgiven solution,
( b) Determination of the pka value of a g''''n Weak add(formie/acetic/prollionic) potentiom~lrically.
9. (a) Determination of plaleau voltag~ of GM ""unterand its •• ,olutioll time.
(b) Delermination of Ema'_10, Critical ,olution temperature for phenol-water s1'tern
and effect of addition .of salt on lhe critical solution temperature.
RSC.,CH. .. 3
Group B (Setect •.••). 10 E"p"irncDts) ,
1. Determine ,tability coN'''''t of Ii by distribution method.2. Determine molecular weight of a high polymer by vi,co_
•ily lll"lhod.3. Determin:lti<Hl of the app,-o"irn,aIC,ize cf oleic acid an4.
calculate Avogadro number. ~
4. Delerrn<nat;OIIof 'pecllie refractivities of the gil"n pureliquid, A and B and (\elc-rminalioll,of the peceentage compositionof given mi~lure of A and B.
5. Estimation of amount of NaC! in a given <olution bypotentiometric titration.
6. Delwnlnalio.n of degree of hyd,oly>e, of aniline hydro-chloride by PH meIer.
1. Determination "r energy of activation of a reaction bet.ween K,S,O, and KI.
8. Study of lhc kineti"" of iodination of acetone, Calaj~"Cdby acid by iodometry
9. DeterminaliC>rlof molecular weight of ben,zeue or lolti.ncor ,,"-roon lell1l dloride by .team diotillation.
10. Delel'minatlc>n or formal •• <lex potential of Ferrous"Ferric sy'l",n p~tenliomclrically.
II. C<Jlorimetric determination of Cr,Oi" and Mrl.' )simu!taneomly in a given mixture in dilute sulphuric add medium_
12. E'timuion of iead in lead nilrale by conductometrictitration with sodiUm ,uIDhnlc.
13. C<Jmpati,ion of the reiatiw 'trcltl!th. Df Hel and H,So.hy rota,uring the ral •• of hydrolysis of an •• ter.
14. Determination of Db value of a given weak acid byPH metric titr"-tion with strona OO,e,
15. Compari,ion of catalytic elr""" of formale and acetateions in iodiltation "f aniline.
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Relermoos ,,'L Experiment' III General Chel~lj;try by C. N. R, Rao and
V, C. Agrawala2.. Pract;cal Ph},ieal C1lemistry b~' A. Findlay,3. Loborolory. manual of Pl".ical Chemislry by W. J, Popiel.4...,A lexl.hook of quanlil.t;vc inorganic analy,is by A, l. Vogel,
Third Eda.
. (iB.S:~:(Chem-klrl'),"!\
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IMrganic Chemi,lry Practical. :,,
Group A (Compul.ory-IO SessioD8)]. Qua]imtive aniiiy.,. of lWOcali(;ns and t\\'o anion, together
fr~;" a mixture or 'p<)wders ;~c1uding"pllO'phate, and' borates.(At least 6 mixhw" ,ho~ld b, analYilOd.)
2. Gravimetric e,tim:ilion of '", (a) Pb"as PbC,O • ."'.
(b) Ni a, Ni (DMG) Complex.3, Volumetric estimation of (any two) :
(a) Chloride by Voihard method."(b) Mnby Volha,d method.' .':'( 0) Mq by disodi\lm EDTA including a, ,tandardisation.
Group B (Toml IO Ses,ioos) ,(I) Following 5 'C,sion, are oompul,ory :I. Colorimelric estimation of (any two) :, ',', <.
(a) Chromium (by diphenyl carbazid.)(b) Titani\lm (by H,o:z)(") Cobalt (by R-. Nitros,osalt).
,o1
"'- 2, Dc,oclion of eatiollij From a binary mixtnre by paper'I' chromotography (at I.ast,. two mixtures should bo. analy'cd).(Cation, ror ,tudy_C~H, AI'+, Fe2+, Ni'+, eo>+, Mnr,Zn:Z+),
,i'\ 3, Vol\lmetric eslimatioll of iron from portland cement using,umdard ,olution of K,Cr,O",by both tho internal and extern']I\"'''''",~"",'"".
"(II) Any 5 """ion, from the following ,
l. Qualitative analysis of II mixture colltaining {we>cation'by spot test. (at J •••••• 12 mixture, ""ouId be analysed) (Cations forstudy-Fe'+ • MnH, 0.'+. Ni'+ , SII'+ • Sb'+ , Hg'+ , Cu"" ).
2. Eotillllllic>uof antimony in type metal (alloy) by per- "manganate method.
J. E,timatiOll of tin and lead in solder ( alloy) using di,odi )EDTA. I
4. Delennil1lltionof Pho'phorus as P,O, in phosphlliiofertilizer sample.
5. Determination of hardness of waler.6.' Volumetrio eslUnalionoftitanium using 8--<julnolinol and
pola"ium bromate.7. Preparation of kincchlo', •••!t.8. Preparation of trio eihylem diamone Ni(n) lhi"•
•ulphale.9. Colorimetricesti"",!;on of;
(" 1 Iron fTOm haenwslobin in liven "''''ple of bk."d( b) Inorganio ph<»ph&lein blood by Fi.kc and Subba
Row, method. If pol&ible vi';1 10 • Chemical Plantor induOlry may be.
T.Y.B.S.c. (Chemistry)
Orgonie Chemistry l'rae"caIs :
Gr••••p A (Compul_y)-( Tells-i0llll)
(I ) Pre{U1raliM of deri-;aIiO'e,' (Any r"",) :(a) Acety1.(b) 2, 4--Din;ITo, phenyl h)"drazone.(,) SernicarbaZOll<t.
2, T~lq\I<:s Of Organic Chemistry-"(a) Thin lay"," ~hromatography.
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( 2 ) ,,'"
"-], Single atage preparation (any two):
(a) Nitrol;on (Bcnzone 10 m.di.nitro benzene).( b) Bromilliltion (Aniline to !ribromo-aniline).(,,) OxidatIon (HydwquillOllC to quinone).(d) Sand meyer reaction (Anthranilic acid t<;> o-ebloro
benzoic acid).(e) Acetylation (Salicyclic acid to aspirin.)(f) Hydrolysi, (Methyl be11ZQ1l.te10 benzoic acid). (2)
4. Separation of mixtures (two components), live mixluresto bean.lysed. (5)
(n
''l3, Synthesis of oommercially valuable chemical. (any 111'0):
(,,) Aspirin.( b) Paracetmol.(c) Methyl salicylate.(d) Phtnolphtllalain.(e) M~lh~1orange.(f) Polystymte. (2)
1. Estimotions (Any five) ,
(aJ Of amide by hydrolysi •.(b) Of cster by hydroiy';'.(c) or gillcooo by hypoiodite method .
..' (d) Component. in APe tablets.~ (c) Of ,ulph drugs.; (fl Of protein by biuret.
) (g) Of urea by urease method.
rr _~ (I 2. _Column chlOmatography.
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4. NaturalPradae,. (Any fOll'-eqaivaicnt 10 2 ••"ions) :(a) &!ponification value of an "iL(b) 1<.Qiationand e,timation of'[arch in poUlIO.(c) Preparation of caffe;ne r"'m tea lea •.•,.(d) Delection and eotimalion of un,aluralioll in ojls. \(e) Detection or anthoc)nanin, from plan" (by TLC J.(I) Es{imation of vilamin C ) I(g) I'''!alion of lipid. from ground nut oil and chal'.. ' "1'
lori,a[ion(by TLC). (4) "
) i,.,
Printod at ; The Poona Un;",,.,ity Pre", Gaoeshkhind, Punc-7;Printo><!and PabJj,hod by ; Shri V. S, Pol, Regi,trar,
University of Poana, Gan""h~hind, Pune-7.500---1-89 (1632)