neuropsychiatric epidemiology research unit (neru)...the neuropsychiatric epidemiology research unit...

The University of Western Australia School of Psychiatry and Clinical Neurosciences

Neuropsychiatric Epidemiology Research Unit (NERU) Annual Report 2016 1995-2015 Historical appendices

Neuropsychiatric Epidemiology Research Unit ANNUAL REPORT 2016 2

Cover page. TF McNeil. “Bright Windows” 2007 Inside front cover. TF McNeil. “Parrot Left, Duck Right" 2016 Inside back cover. TF McNeil. “Vertical Lines in Blue and Ochre” 2007 Bottom borders. TF McNeil. Detail from “Vertical Lines in Blue and Ochre” 2007


NERU. A mountain in Himavā. All birds settling there become golden

The Neuropsychiatric Epidemiology Research Unit (NERU) is recognised for its expertise in psychiatric epidemiology,

and its cross-disciplinary approach to the study of psychotic disorders including schizophrenia and other severe mental illness.

http://www.psychiatry.uwa.edu.au/research/neru



TF McNeil. “Face look” 2012


CONTENTS

CONTENTS 5

FOREWORD 6

IN MEMORIAM: BARBARA FISH 1920-2016 8 NEUROPSYCHIATRIC EPIDEMIOLOGY RESEARCH UNIT 10

OUR PEOPLE 2016 11

STRUCTURE 2016 12

OUR RESEARCH PROGRAM 13

METHODOLOGIES and APPROACHES 15

INSTRUMENTS, ASSESSMENT TOOLS and ALGORITHMS 16 RESEARCH PROJECTS: Life course studies of pathways to psychotic disorders and other severe mental illness 19

RESEARCH PROJECTS: Other whole population record-linked register-based research 24

RESEARCH PROJECTS: SHIP and related clinical and large-scale epidemiological surveys 26 RESEARCH FUNDING RECEIVED/ 2012 ONWARDS ($) See Appendices 1a and 1b for funding 1995-2011 33

PUBLICATIONS 2016 36

ORAL CONFERENCE PRESENTATIONS 2016 38

POSTER PRESENTATIONS 2016 38 OTHER TALKS AND PRESENTATIONS 2016 39

POSTGRADUATE STUDENTS 2016 41

VISITORS 2016 42

RESEARCH COLLABORATIONS AND ACTIVITIES 2016 43

STAFF: AWARDS AND PRIZES 2016 46

STAFF: CONFERENCE ORGANISING COMMITTEES 2016 47 STAFF: EDITORIAL COMMITTEES 2016 47

STAFF: FORMAL OFFICES & COMMITTEE MEMBERSHIP 2016 48

STAFF: CURRENT PROFILE 49

APPENDICES 54

APPENDIX 1a. Research Funding 2004-2011 ($) 55

APPENDIX 1b. Research Funding 1995-2003 ($) 56 APPENDIX 2. SELECTED PUBLICATIONS 1995-2015 (Epidemiology) 57

NERU LOCATION AND CONTACT DETAILS 74


FOREWORD

From Head of School, School of Psychiatry and Clinical Neurosciences (2016): Professor Sean Hood

The Neuropsychiatric Epidemiology Research Unit (NERU) continues to thrive. Under the leadership of psychiatric epidemiologist Professor Vera Morgan, the Unit has secured funding for its key programs to 2020 and beyond. Using a broad cross-disciplinary approach to the study of neuropsychiatric disorders - especially schizophrenia and other psychotic disorders – it has produced research this year consolidating its status as an internationally-renowned centre for expertise in psychiatric epidemiology.

NERU led the National Study of High Impact Psychosis (SHIP) using its extensive experience of record-linked population health, social services and criminological databases and this study is continuing to have a national and international impact. NERU’s unique expertise with the Western Australian linked case register and its development (in conjunction with the Centre for Clinical Research in Neuropsychiatry) of specialised assessment tools such as the SIMPAQ and McNeil-Sjöström Scale for Obstetric Complications list amongst its key contributions this past year.

The profile and productivity of the members of this Unit is attested to by their significant publication record, convening of national conferences, leadership in esteemed national and international professional bodies and their competitive grant success. The Unit’s relationship with North Metropolitan Area Mental Health Service in the provision of research-informed care to patients with psychotic disorders is a key translational outcome, and I am also pleased to see the highlighting of several other “Translation” outcome boxes in this year’s report, which attest to the significant and broad clinical impact of NERU research.

As we move into a post-Reform period at UWA, I am pleased to confirm that the Neuropsychiatric Epidemiology Research Unit will continue to reside within the UWA Medical School as a key component of the School’s mental health portfolio. I am hopeful that we will be able to build upon the academic capacity of the Unit with the establishment of new academic position(s) this year.

Professor Sean Hood Associate Dean (Community & Engagement)

Faculty of Health & Medical Sciences, The University of Western Australia


From the Head, Neuropsychiatric Epidemiology Research Unit: Winthrop Professor Vera Morgan

The NERU Strategic Planning Day held at the start of 2016 provided an excellent opportunity to reflect on what the Unit has achieved since its last major Planning Day in 2011. We have come a long way. In 2011, we were most concerned about finding sufficient funding for the two arms of our research program. We not only found funding but, today, we have three NHMRC grants that continue to fund those programs through to 2020. We also have some exceptional data to exploit over this period, data that are in excellent shape due to several years of collection, cleaning and operationalising.

The assets that NERU has grown and that it takes with it into the future include:

• An excellent record of winning competitive grants and government contracts totaling $16.8 million since 2000.

• A growing record of publications.

• Breadth of scientific, clinical and methodological expertise among its staff covering: psychopathology; birth defects and intellectual disability; physical health morbidity and mortality, incl. reproductive pathology, obstetric complications and cardiometabolic disease; social determinants of outcome; criminology; epidemiological methods, biostatistics, record linkage; clinical assessment, diagnostic classification; instrument design.

• Its own server holding an Ingres relational database of over 8 million records – and the internal expertise within its academic staff to manage the database.

• Very high quality international, national and local collaborators.

In his wrap-up remarks at the end of our planning session, Professor Thomas McNeil, a long-time colleague and collaborator from Sweden, said: “To be successful, you have to love what you do”. Perhaps NERU’s greatest assets are that we do love the work we do, despite the many challenges that externally-funded research staff face, that we support one another through these challenges and other difficulties as we forge ahead, and that we do so with much humour and much consideration.

On a different note, pre-eminent US psychiatrist and researcher Dr Barbara Fish died in 2016. Dr Fish’s seminal work on pandysmaturation lay the ground for the formulation of the neurodevelopmental hypothesis of schizophrenia in the late 1980s. This hypothesis continues to exert a powerful influence on our understanding of the aetiological basis of schizophrenia. Both the neurodevelopmental hypothesis and Dr Fish’s approach to studying children of mothers with schizophrenia at high risk of developing schizophrenia themselves lie at the core of our life course studies.

Finally, I thank Professor Thomas McNeil and Maddie Di Prinzio for allowing me to share their wonderful works of art with you, through publication in this annual report. Most of the paintings of Professor McNeil that are displayed here were produced over the course of his many visits to the Unit and, as such, have a special significance for the NERU team.

Winthrop Professor Vera Morgan Head: Neuropsychiatric Epidemiology Research Unit


IN MEMORIAM: BARBARA FISH 1920-2016

Photos: Barbara Fish 2009, 1963 Dr Barbara Fish (UCLA Della Martin Professor of Psychiatry, Emerita) is widely recognised for her pioneering research into early neurological deviations in the development of children born to mothers with schizophrenia. Her longitudinal studies of such high-risk children established that the emergence of schizophrenia spectrum disorders later in life was antedated by a particular syndrome of deviant cerebral and neuromotor abnormalities detectable in the first year of life and termed pandysmaturation. Her findings pointed to genetic origins of the early neurobehavioural deviations that could lead to serious psychopathology in later life. These findings, elicited by Dr Fish’s astute clinical observations of developmental pathology in progress, laid much of the groundwork for what has come to be known as the neurodevelopmental model of psychopathology, a paradigm that is broadly accepted in the field of schizophrenia research today. At the time of publication of her first paper (“The detection of schizophrenia in infancy") in 1957, this was regarded as a revolutionary, almost heretical, paradigm-shift, but with time and further

supporting evidence it would replace the “schizophrenogenic mother” as the putative cause of schizophrenia, according to the then dominating psychoanalytic theory in American thinking. The resolution of this conflict of theories and the acknowledgment of the importance and acceptance of Barbara’s work was carved in stone in 1987, when she received the prestigious Agnes Purcell McGavin Award from the American Psychiatric Association "for outstanding contributions to the prevention of mental disorders in children, including groundbreaking research on the long term outcome of infants born of schizophrenic mothers". More recently, in 2009, she was awarded the International Congress on Schizophrenia Research (ICOSR) Service Award at a symposium organised in her honour which included tributes by long-time colleagues and friends, including ourselves, who recalled what must have been the very first meetings on high-risk research, sponsored by WHO in the early 1980s in Moscow and then in Geneva, at which Barbara was the keynote speaker.


Barbara’s life was an intellectual and physical journey from East coast to West coast in the US, with a side trip or two around the world. Born in New York City, she was introduced to the world of science by her father (a mechanical engineer), and obtained her education at outstanding schools (the Ethical Culture School in New York City; the Barnard College; and New York University College of Medicine, with training in psychoanalysis at the William A. White Institute of Psychoanalysis). She later held many esteemed academic appointments in New York and California, culminating in 1989 in her appointment as UCLA Della Martin Professor of Psychiatry, which she extended as Emerita on her retirement in 1991. Several factors contributed to Barbara’s remarkable scientific success. First and foremost, she was exceptionally bright and intellectually innovative, one example of which was her being awarded the Alpha Omega Alpha medal for the highest scholastic ranking over the four-year course of medical education at New York University College of Medicine. Secondly, outstanding students attract outstanding teachers, and Barbara was deeply influenced by her mentor, Dr Lauretta

Bender, and equally by her husband, Max Salzman, himself a highly regarded scientist. Thirdly, Barbara’s personality - energetic, curious, honest, vivacious, persistent, demanding - undoubtedly contributed greatly toward her lifetime success and the support and stimulation given by her collaborators. For those of us who had the privilege of knowing Barbara Fish, she leaves indelible snapshots of her personality - e.g. Barbara on a NIH site visit, elegantly dressed in a billowing fur coat; or a key-note speaker descending the stairway in Moscow; a private Barbara at home sorting energetically through the deep piles of professional papers and writings that made up much of the fabric of her life; an honoured Dr Barbara Fish at 89 years of age, relating her experience of a lifetime of research in schizophrenia at the 2009 ICOSR symposium in San Diego; and last but not least, Barbara Fish brimming with life, sitting alone at a bar, enjoying a glass of red wine at the end of a scientific conference. These and many more facets made up the life of this complex and truly outstanding person who, in turn, made our lives and knowledge so much richer.

Assen Jablensky, Thomas McNeil and Vera A. Morgan

Selected bibliography of Dr Barbara Fish Fish B. The detection of schizophrenia in infancy. J Nerv Ment Dis 1957; 125:1-24. Fish B, Shapiro T, Halpern F, Wile R. The prediction of schizophrenia in infancy: III. A ten-year follow-up

report of neurological and psychological development. Amer J Psychiat 1965; 121:768-75. Fish B. An approach to prevention in infants at risk for schizophrenia: Developmental deviations from birth to

10 years. J Amer Acad of Child Psychiat 1976; 15:62-82. Fish B. Neurobiologic antecedents of schizophrenia in children: Evidence for an inherited, congenital

neurointegrative defect. Arch Gen Psychiat 1977; 34:1297-1313. Fish B, Dixon WJ. Vestibular hyporeactivity in infants at risk for schizophrenia. Its association with critical

developmental disorders. Arch Gen Psychiat 1978; 35:963-971.

At home with Barbara Fish, Los Angeles 2009


NEUROPSYCHIATRIC EPIDEMIOLOGY RESEARCH UNIT

NEUROPSYCHIATRIC EPIDEMIOLOGY RESEARCH UNIT The Neuropsychiatric Epidemiology Research Unit (NERU) is recognised for its expertise in psychiatric epidemiology. The Unit takes a cross-disciplinary approach to the study of neuropsychiatric disorders, especially schizophrenia and other psychotic disorders, that melds epidemiological, psychiatric, criminological and sociological perspectives on aetiology, course and outcome for people burdened with these disorders to help unravel their complex aetiology. NERU has developed and enhanced a number of instruments,

assessment tools and computer algorithms to facilitate the clinical assessment of psychopathology and physical health in people with severe mental illness. The Unit has a long history of success in attracting national, international and government funding to support its program of research. NERU offers excellent infrastructure, including information technology and physical infrastructure to support the work of its staff. Currently, NERU has 3 NHMRC grants.

OUR RESEARCH TEAM The Neuropsychiatric Epidemiology Research Unit is made up of committed researchers from a variety of disciplines, including experts in: psychopathology; birth defects and intellectual disability; physical health morbidity and mortality, including reproductive pathology, obstetric complications, and cardiometabolic disease; social determinants of outcome; criminology; epidemiological methods, biostatistics and record linkage; clinical assessment and diagnostic classification; and instrument design.

Winthrop Professor Vera Morgan is the Head of NERU. NERU works very closely with Professor Assen Jablensky, Director of the UWA Centre for Clinical Research in Neuropsychiatry, who is the Chief Scientific Adviser to NERU. Ms Stephanie Gee is the Senior Administrative Officer supporting the work of NERU. The breadth of scientific, clinical and methodological expertise, professional skills and experience that these staff bring to the Unit are its greatest assets.

NERU and collaborators from the Centre for Clinical Research in Neuropsychiatry


OUR PEOPLE 2016

Ms Stephanie Gee Senior Administrative Officer

Prof Assen Jablensky Winthrop Professor Senior Scientific Consultant

Director: UWA Centre for Clinical Research in Neuropsychiatry

Dr Maxine Croft Assistant Professor Epidemiologist / Biologist

Ms Patsy Di Prinzio Research Associate Biostatistician

Ms Jenny Griffith Project Manager SHIP Wave2 deputy coordinator / Mental Health Clinical Research Nurse

Dr Ashleigh Lin Post-doctoral fellow Visiting research fellow / Post-doctoral fellow: Telethon Kids Institute

Ms Taryn Major Assistant Professor Biostatistician

Professor Thomas McNeil Adjunct Professor Visiting professor

Ms Giulietta Valuri Assistant Professor Epidemiologist / Criminologist / Database Administrator

Ms Anna Waterreus Assistant Professor Coordinator SHIP WAve2 / Mental Health Clinical Research Nurse

SHIP Wave2 Survey

Data entry: Hannah Castle Joshua Castle Samantha Poulsen

Software development: Matt Walsh

IT systems development Damian McGuckin


STRUCTURE 2016

Figure 1. Organisational structure, Neuropsychiatric Epidemiology Research Unit, 2016

NERU Planning Day, 2016


OUR RESEARCH PROGRAM

One arm of our research relies on linkage of the Western Australian psychiatric case register to an extensive network of other electronic State health and social services registers. Since 1995, most of this work has focused on the relationship between environmental risk factors and genetic liability for schizophrenia and other neuropsychiatric outcomes including, but not limited to, birth defects, intellectual disability, pervasive developmental disorders, epilepsy, psychiatric illness and psychotic illness. Topics include:

• NHMRC: Impact of social adversity on the developmental trajectory to mental illness

• NHMRC: Life course trajectories and neuropsychiatric outcomes in an e-cohort of high risk children of mothers with psychosis

• NHMRC/March of Dimes/Stanley: Pregnancy, delivery, and neonatal complications in a population cohort of women with schizophrenia and major affective disorders

• NHMRC/March of Dimes/Stanley: Intellectual disability comorbid with schizophrenia and other psychotic disorders

• Stanley: Influenza and season of birth: are these environmental risk factors for schizophrenia?

Several other projects also rely on the use of linked register data:

• NHMRC/Commonwealth contract: The association between schizophrenia, victimisation and criminal offending

• NHMRC Partnership: Evaluation of the impact of Australian perinatal mental health reforms on service utilisation and related cost-effectiveness

• State contracts: Other mental health service evaluation and planning

The second arm of our research is involved in clinical and large-scale epidemiological surveys of the prevalence of psychotic illness in Australia, and the characteristics of those affected. The Unit has been responsible for leading Australia’s two national surveys of psychotic illness, in 1997-98 and in 2010. Since then, we have received NHMRC funding to follow-up National and State psychosis surveys, both face-to-face and through record-linkage to their health records. The five main projects that we have undertaken are:

• NHMRC: An empirical framework for assessing mortality and morbidity in people with psychotic disorders: A 7-year prospective and 10-year retrospective follow-up of 2075 participants in the Survey of High Impact Psychosis (SHIP) using linked registers 2016-2020

• NHMRC: Overcoming barriers to improved physical health in people with severe mental illness (SHIP WAve 2): 2013-2016

• State contract: The 2012 North Metro Survey of High Impact Psychosis (North Metro SHIP)

• Commonwealth contract: The 2010 Australian National Survey of High Impact Psychosis (SHIP)

• Commonwealth contract: The 1997-98 Low Prevalence (Psychotic) Disorders Study (LPDS)


TF McNeil. "Birds of a feather play together" 2016


METHODOLOGIES and APPROACHES

Record linkage across population-based registers including multigenerational approach The Neuropsychiatric Epidemiology Research Unit has extensive experience in the use of multigenerational cross-linked data from the Western Australian psychiatric case register, State health (e.g. morbidity, birth defects, midwives, mortality) and other registers (e.g. criminal; intellectual disability; cerebral palsy; cancer; child protection and education) to study prevalence, incidence, aetiology and risk factors.

http://www.ncbi.nlm.nih.gov/pubmed/20870781

http://www.ncbi.nlm.nih.gov/pubmed/20592426 Risk factor epidemiology Record linkage methodology has been the basis of the epidemiological study of risk factors for schizophrenia and other psychosis. These have included: obstetric complications; influenza; and season of birth.



Large scale epidemiological surveys The Neuropsychiatric Epidemiology Research Unit is experienced in the design, instrument development and coordination of large national multisite surveys and the Unit includes highly skilled research staff with clinical mental health expertise. It has had responsibility for the conduct of Australia’s two national psychosis surveys: in 1997-98, the first national survey of psychosis, the Low Prevalence (Psychotic) Disorders Study and, in 2010, the second national Survey of High Impact Psychosis (SHIP). In 2012, it undertook a SHIP extension study in north metropolitan Perth, the North Metro Survey of High Impact Psychosis (North Metro SHIP).


http://www.ncbi.nlm.nih.gov/pubmed/10789527 Clinical assessments and reviews See section of Instrument Development for approaches to the clinical assessment of psychopathology and physical health, and the conduct of clinical casenotes reviews.








INSTRUMENTS, ASSESSMENT TOOLS and ALGORITHMS

The Neuropsychiatric Epidemiology Research Unit has developed a number of instruments, assessment tools and computer algorithms. Many have been developed in collaboration with the Centre for Clinical Research in Neuropsychiatry. Most of these are available for use by external researchers, subject to certain undertakings. For more information, contact Stephanie Gee (+61) 8 9224 0290 Psychosis Screener A Psychosis Screener has been developed to identify individuals likely to meet criteria for formal diagnosis of a psychotic disorder. The Psychosis Screener was originally developed for the Low Prevalence (Psychotic) Disorders Study 1997-98 and further modified for the Survey of High Impact Psychosis 2010. It is a brief instrument (one page) covering 8 items and takes 1-2 minutes to complete. There are patient and keyworker versions.


http://www.psychiatry.uwa.edu.au/research/neru/publications/survey#SHIP-report

http://www.ncbi.nlm.nih.gov/pubmed/10789527 Diagnostic Interview for Psychosis – Diagnostic module (DIPpc-DM 1.0) The Diagnostic Module of the Diagnostic Interview for Psychoses (DIP-DM) is a semi-structured interview consisting of the 97 items of the Operational Criteria for Psychosis (OPCRIT). The DIP-DM uses probes and differential definitions derived and adapted from the WHO Schedules for Clinical Assessment in Neuropsychiatry (SCAN). A computer algorithm generates diagnoses using the underlying OPCRIT algorithm. The development, reliability and applications of the DIP have been published. The current version is DIPpc-DM1.2. The DIP-DM is being used in New Zealand, UK, US and, in translation, in Indonesian, Italy, Spain, France, Greece, Norway, Mongolia, Russia and Bulgaria. A self-executing PC version of the software was developed and distributed in 2013.



Diagnostic Interview for Psychosis. Complete assessment schedules We have available for reference and use the full interview schedules from both Australian National psychosis surveys: The Survey of High Impact Psychosis 2010 (SHIP) and the Low Prevalence (Psychotic) Disorders Study 1997-98 (LPDS). These include the 33 SHIP modules and the three LPDS modules. The main domains covered by the 2010 SHIP survey include:

• Clinical profile

• Cognitive profile

• Social participation and functioning

• Measures of impairments and disabilities

• Socio-economic profile

• Service utilisation, treatment and perceived need for services

• Measures of quality of life In the development of the national SHIP survey instruments, the primary consideration was to include measures that: were reliable; were available; were cost and time effective; and allowed comparison with other collected data. Replication of questions from the first survey (LPDS) in 1997-98 has provided a rare opportunity to assess change over time. Use of questions from the 2007 National Mental Health Survey has allowed benchmarking of findings against general population data.















Brief Cognitive Assessment Tool A Brief Cognitive Assessment Tool was developed for the 2010 National SHIP survey to assess cognition and was included in the interview schedule. The selection criteria for inclusion of a task within the tool were that the task should be brief (total testing time of 10 minutes at most), easy to administer in a range of contexts (for example, pen and paper based), not restricted to use by psychologists, and able to provide valid measures of cognitive ability in psychosis. The two tasks finally selected were: National Adult Reading Test (NART) Revised (Nelson and Willison, 1991); and Digit-Symbol Coding Test (DSCT) from the RBANS battery (Randolph et al.). The purpose of the NART is to provide an estimate of premorbid intellectual ability (specifically WAIS-R IQ). NART taps into crystallised intelligence and is less likely to be affected by disease processes. There are good population norms for the NART. An additional advantage of the NART is that it is no longer copyrighted and there are no specific user qualifications required. DSCT taps into non-verbal functions (e.g. attention, flexibility, speed of processing and abstraction) that are much more likely to be affected by disease processes. The DSCT has a number of advantages. Population norms are available, it is well-known and well-regarded, and administration is simple with no requirement for complex equipment. Users must be trained but not necessarily psychologists.


SIMPAQ An International Working Group (clinical and academic experts from more than fifteen countries including Anna Waterreus) has developed a brief, easy to use, physical activity questionnaire which assesses sedentary and low intensity behaviours in people with mental illness - the Simple Physical Activity Questionnaire (SIMPAQ). The inclusion of physical activity programs into mental health services can improve the health outcomes of people with mental illness, but physical activity is difficult to measure. Existing questionnaires are limited in their ability to measure sedentary behaviour. The Simple Physical Activity Questionnaire (SIMPAQ) is a newly developed interview-based physical activity measurement tool. It is a five-item questionnaire based on activities undertaken in the previous seven days. SIMPAQ assesses combined physical activity across all domains including leisure time, domestic, work and transport-related activities. It should take between three to eight minutes to complete and can be administered by clinicians or researchers. It is currently being translated into multiple languages for use and assessment in different cultural contexts (i.e. Portuguese, German, French, Spanish, Farsi, Icelandic, Norwegian and Chinese). A validation study comparing the data obtained via SIMPAQ to objective accelerometer based measurements is currently being undertaken in over 25 centres in more than 15 countries. http://www.simpaq.org


http://www.simpaq.org/


McNeil-Sjöström Scale for Obstetric Complications The McNeil-Sjöström Scale for Obstetric Complications operationalises the scoring of hundreds of obstetric complications and their treatment, ranging from common to rare. The scale is underpinned by both biological and aetiological considerations and is designed to take a better account of the amount, timing and severity of obstetric complications. The McNeil-Sjöström Scale was developed by Professors Thomas McNeil and Karin Sjöström in Sweden. It produces separate summated scores indicating the number of complications of a particular severity level for each of three time periods (pregnancy, labour and delivery, and the neonatal period) as well as producing an overall score. NERU has developed an updated version including complications found in the southern hemisphere and rarely encountered in northern hemisphere countries. We have also written a computer algorithm to automate the scoring of obstetric complications recorded on electronic pregnancy/obstetric databases. These developments were done in close collaboration with Professor McNeil. Measures of longitudinal maternal morbidity Algorithms have been written using all longitudinal maternal health data on the Midwives Database to produce a full estimate of maternal morbidity at the time of childbirth. Children’s Checklist Children’s Checklist was developed by the Unit specifically for the collection of children’s data on substance misuse, psychotropic medication use, behavioural problems, neuro-cognitive data and psychopathology not recorded in the Diagnostic Interview for Psychosis. Measures of adversity Indicators of exposure to adverse life events and adverse social, familial and physical environments are being systematically extracted from the linked electronic records. These indicators will be combined in clinically and mathematically meaningful ways that will allow them to be used as predictors of outcome in our risk factor research.


RESEARCH PROJECTS:

Life course studies of pathways to psychotic disorders and other severe mental illness

Environmental and familial risk factors for psychotic illness and other neuropsychiatric outcomes V Morgan, G Valuri, M Croft, S Shah, P Di Prinzio, J Griffith, T Major, T McNeil, J Björk, F Morgan, K Abel, A Jablensky

Study Design: Environmental and familial risk factors for psychotic illness and other neuropsychiatric outcomes

Our aim is to integrate genetic and risk factor epidemiology under a developmental perspective in order to examine reproductive pathology in women with severe mental illness and follow-up proximal and distal developmental and neuropsychiatric sequelae in their children.

Children at increased familial risk for severe mental illness are compared with children at no increased familial risk on a wide range of

developmental indices and environmental risk factors, including obstetric events, with a view to elucidating the intergenerational transmission of both vulnerability and resilience to adverse neuropsychiatric outcomes. These outcomes include, among others, birth defects, intellectual disability, pervasive developmental disorders, epilepsy, psychiatric illness and psychotic illness.


We have three overarching hypotheses: 1. Neuropsychiatric disorders including

schizophrenia, bipolar disorder, autism spectrum disorder, epilepsy and intellectual disability, as well as certain rare congenital anomalies, will tend to cluster in families.

2. Children of mothers with severe mental illness will be at increased risk of a spectrum of such outcomes.

3. Obstetric complications and other environmental exposures, especially exposure to social adversity, will contribute to the offspring outcomes, either independently or in interaction with the parentally transmitted genetic risk.

This is a whole population record linkage study, using linkage across psychiatric, physical morbidity, mortality and other administrative registers in WA to follow up a large cohort of 467,945 children born between 1980 and 2001 to 246,874 mothers. This includes 15,486 births to 7508 mothers with a psychotic illness. Currently, we are examining the following outcomes:

• Maternal reproductive morbidity and early neonatal morbidity (lead authors: M Croft/T Major)

• Stillbirths, perinatal and childhood mortality (lead authors: S Shah/Patsy Di Prinzio)

• Early neuropsychiatric outcomes including birth defects, intellectual disability and rare syndromes (lead author: Patsy Di Prinzio)

• Criminal offending (lead author: G Valuri) We are in the final phase of this project. We have started to explore the role of adversity on risk of developing a psychotic illness, and are in the process of constructing an adversity scale. Once completed, we will be able to address the hypotheses (see above) for our flagship paper examining familial and environmental risks for psychotic illness in these high risk children of mothers with schizophrenia and other psychotic disorders.

The study design has been published: http://www.ncbi.nlm.nih.gov/pubmed/20870781 Works published using the full cohort include: https://www.ncbi.nlm.nih.gov/pubmed/27131155 http://www.ncbi.nlm.nih.gov/pubmed/28093927

Works published using a smaller cohort include: http://www.ncbi.nlm.nih.gov/pubmed/22241931 http://www.ncbi.nlm.nih.gov/pubmed/15625205

TRANSLATION Findings of adverse obstetric outcomes for

the offspring of mothers with psychotic disorders resulted, in collaboration with the

Clinical Applications Unit, in the development of a care coordination package, leading to implementation of a State care-coordination program for pregnant women with severe mental illness, the first of its kind in Australia. To disseminate findings

widely among clinicians, they were published in Directions in Psychiatry ("Exemplary

Status" by Accreditation Council for Continuing Medical Education).


https://www.ncbi.nlm.nih.gov/pubmed/27131155





TF McNeil. “Mothers and …” 2014


Intellectual disability and maternal psychotic illness P Di Prinzio, V Morgan, J Björk, T McNeil, A Jablensky We have a series of studies that have reported on the prevalence of intellectual disability in people with schizophrenia and explored the nature of the association between psychotic disorders and intellectual disability, including the role of familial liability for neuropsychiatric illness and confounding by obstetric complications. Ongoing work is re-examining the relationship between maternal psychotic illness and intellectual disability in offspring in a cohort of half a million children. Publications to date include:

• Epidemiology of intellectual disability co-occurring with schizophrenia and other psychiatric illness: population-based study: The epidemiology of intellectual disability co-occurring with schizophrenia and other psychiatric illness http://www.ncbi.nlm.nih.gov/pubmed/18978313

• Intellectual disability comorbid with schizophrenia and other psychotic disorders


TRANSLATION These data added to accumulating evidence

of an association between pervasive cognitive deficits and schizophrenia, and support findings of an excess of multiply-affected families. They also highlight the

extent to which comorbidity is underestimated due to the administrative

divide between mental health and intellectual disability services, leading to poor access to much-needed services. The data have been used by the Department of Health to develop policy for people with

these special needs.

Influenza and season of birth: Environmental risk factors for schizophrenia? V Morgan, D Castle, A Jablensky In addition to obstetric complications, a number of studies have explored the association between other environmental exposures and schizophrenia. Publications to date include:

• Influenza epidemics and incidence of schizophrenia, affective disorders and mental retardation in Western Australia: No evidence of a major effect

www.ncbi.nlm.nih.gov/pubmed/9376335

• Season of birth in schizophrenia and affective psychoses in Western Australia 1916-61

www.ncbi.nlm.nih.gov/pubmed/11473508

• Schizophrenia and 1957 Pandemic of Influenza: Meta-analysis








Swedish collaborators: Thomas McNeil and Jonas Björk


RESEARCH PROJECTS:

Other whole population record-linked register-based research

The association between psychotic illness, criminal offending and victimisation V Morgan, F Morgan, G Valuri, S Shah, A Ferrante, D Castle, A Jablensky

Criminal offending The study The prevalence and patterns of criminal offending in schizophrenia and other psychiatric disorders indicated that the vast majority (89%) of offenders arrested 1986-1996 did not have a mental illness. Comorbid substance abuse disorder significantly increased risk of a violent offence for people with schizophrenia. For the majority of offenders with a mental illness, their first arrest preceded their first contact with mental health services. A peak in the pattern of arrests 1991-1993 for people with schizophrenia coincided with a period when community mental health services were poorly resourced to meet demands created by deinstitutionalisation of patients from psychiatric institutions.


The study Area of residence and the impact of social disorganisation and urbanicity on offending by people with schizophrenia showed that the same area-level characteristics that generate high arrest rates for the population as a whole also generate high arrest rates for people with schizophrenia. These include: disadvantage, inequality, ethnic homogeneity and residential mobility. There is no evidence of a multiplier effect. However, compared to the general population, individuals with schizophrenia are more likely to be exposed to social disadvantage and other neighbourhood-level risk factors that predict offending in non-psychotic populations.

http://www.aic.gov.au/documents/C/0/8/%7BC0878787-6326-44B4-9F32-71F0B8A2A596%7Dtandi365.pdf

TRANSLATION These criminological findings have important

implications for policy and program development in both criminal justice and

mental health. They suggest that geographic areas characterised by high levels of social disorganisation require more investment in crime prevention, mental-health services

and criminal justice responses.

Victimisation As part of the 2010 Australian National Survey of Psychotic Disorder, we have collected and analysed data on childhood and adult victimization of people with a psychotic illness. The prevalence of childhood abuse (using Department of Child Protection criteria) was 31%, twice the rate in the general community. Women were almost three-times more likely to report childhood abuse compared to men. People with psychotic illness who had experienced childhood abuse were significantly more likely to have attempted suicide compared to those who had not. They were also more likely to have subjective thought disorder, premorbid personality disorder (females only) and anxiety (males only).

http://www.ncbi.nlm.nih.gov/pubmed/25107848 Rates of adult victimisation were also high. Over a period of 12 months, 39% of people with a psychotic illness had been victimised. Assault victimisation was 17%, five-times the level found in the general community. Rates of assault victimisation were higher for women compared to men, the reverse of the pattern found in the general community. Rates did not show the same attenuation with increasing age that is seen in the general community.


TRANSLATION Victimisation impacts on psychopathology,

course of illness and quality of life. However, neither childhood nor adult

victimisation, nor their sequelae, especially post-traumatic stress disorder, are well

recognised in clinical practice, leading to poor treatment of those affected. Therapies to improve social cognition may help those with psychotic illness recognise and manage

threatening situations and adopt self-protective behaviours in order to reduce

their risk of victimisation.







The Australian perinatal mental health reforms: using population data to evaluate their impact on service utilisation and related cost-effectiveness M-P Austin, E Sullivan, N Highet, V Morgan, C Mihalopoulos, M Croft and T Major, in partnership with beyondblue. This study fills a significant gap in the evidence-base on how key Australian perinatal mental health initiatives have met their goals of increasing service utilisation at this critical time for mother, infant and family. It uses population health data to examine the impact of National Perinatal Depression Initiative reforms on maternal health outcomes, service utilisation and the likely cost-effectiveness of these reforms.

It employs four key methodologies: 1. Data linkage; 2. Generation of perinatal-specific Medicare

Benefits Schedule summary data; 3. Economic and policy analyses; and 4. Key stakeholder consultations in a

consideration of the further implementation and evaluation of the National Perinatal Depression Initiative.

The NHMRC Partnership grant funding the study involves researchers from the University of New

South Wales, University of Western Australia and Deakin University in partnership with beyondblue and the Centre of Perinatal Excellence.

TRANSLATION This study will fill a significant gap in the

evidence-base on how key Australian perinatal mental health initiatives have met their goal of increasing service utilisation at

this critical time for mother, infant and family. It has the potential to greatly

advance the development and eventual inclusion of key mental health-related data elements in the Perinatal National Minimum Dataset and State-based Midwives/Perinatal

data collections. Findings from the study influenced the Australian Labor Party’s 2016 policy platform and is cited in their policy

document.

Project in collaboration with WA Centre for Mental Health Policy Research G Smith, T Williams, V Morgan, D Preen and E Kelty Two studies have been undertaken in partnership with WA Centre for Mental Health Policy Research:

• Patterns of service use for people who have had a psychiatric inpatient admission; and

• Long-term treatment outcomes in early psychosis specialist services.


RESEARCH PROJECTS: SHIP and related clinical

and large-scale epidemiological surveys

2010 Australian National Survey of High Impact Psychosis (SHIP)

2012 North Metro Survey of High Impact Psychosis (North Metro SHIP)

2013-2016 NHMRC Survey of High Impact Psychosis WAve 2 (SHIP WAve 2)

2016-2020 NHMRC An empirical framework for assessing mortality and morbidity in people with psychotic disorders (SHIP follow-up)


2016-2020: An empirical framework for assessing mortality and morbidity in people with psychotic disorders: A 7-year prospective and 10-year retrospective follow-up of 2075 participants in the Survey of High Impact Psychosis (SHIP) using linked registers V Morgan, A Waterreus, A Jablensky, G Valuri, P Di Prinzio and T Major, in collaboration with G Watts, A Tonkin and the SHIP Study Group* It is well established that physical morbidity and premature mortality are elevated in schizophrenia. However, there is a critical need for longitudinal data. This study builds on a unique opportunity to use an innovative dual-methods strategy. We will extract 17 years (2000-2017) of mortality and physical morbidity outcome data from State and national administrative registers. We will add these register data to previously-collected survey data for a large, nationally representative and comprehensively characterised sample of 2075 people aged 18-64 years with psychotic disorders who took part in SHIP and have already given consent to linkage. The aims of this study are to: 1. Estimate rates of 7-year mortality and

morbidity in people with a psychotic disorder, with separate estimates for:

• mortality due to natural versus unnatural causes; and

• potentially avoidable morbidity (i.e. preventable/treatable), in order to establish much needed Australian benchmarks for assessing the impact of changes in public health policies.

2. Examine the impact of sets of risk factors on 7-year mortality and morbidity, in order to move beyond estimation of rates to understanding the aetiology of adverse physical health outcomes in psychotic disorders and informing clinical practice.

3. Develop and validate predictive risk equations for cardiovascular disease (CVD) for use with people with psychotic disorders, in order to address a clinical

need for CVD predictive risk equations appropriate for use in this subpopulation.

4. Calculate the economic burden of severe and acute physical morbidity in addition to mental health impacts, in order to meet a service planning need for accurate data on costs of physical morbidity in psychotic disorders.

*Lead investigators of the SHIP Study Group that developed the survey protocol and continue to oversee the management and analysis of the survey data include: V Morgan (convenor), A Jablensky, A Waterreus, V Carr, D Castle, M Cohen, C Galletly, C Harvey, A Mackinnon, P McGorry, J McGrath, P Morgan, A Neil

TRANSLATION The resultant, consolidated dataset will be an exceptional, cost-effective resource for addressing a diverse range of questions that

usually necessitate recourse to multiple samples. These include: point estimates; aetiology; risk prediction; and cost. The sample size permits fine-level analyses, including examination of natural versus

unnatural causes of death, and potentially avoidable versus other mortality/morbidity.

The sample age structure (18-64 years at time of interview) ensures we can examine

excess mortality and morbidity in early adulthood and middle age, as well as in

older age. The findings will inform policy planning and clinical practice.


Simple Physical Activity Questionnaire (SIMPAQ) A Waterreus in collaboration with the SIMPAQ International Working Group* An International Working Group (clinical and academic experts from more than fifteen countries including NERU’s Anna Waterreus) has developed a brief, easy to use, physical activity questionnaire which assesses sedentary and low intensity behaviours in people with mental illness - the Simple Physical Activity Questionnaire (SIMPAQ). The SIMPAQ has undergone several stages of development and testing and, in 2016, a large multi-country reliability and validity study is being undertaken. A total of 40 people were recruited at the UWA site and participated in this reliability and validity study. *Australia: P Ward (Chair), S Rosenbaum (co-Chair), J Curtis, J Richards, A Bauman / Belgium: D Vancampfort / Brazil: F Schuch, F Moraleida Canada: G Faulkner / Denmark: H Speyer / Finland: S Eskelinen / Italy: A Carraro / Nigeria: R Uwakwa /Switzerland: M Gerber/ UK: B Stubbs, M Ussher, F Gaughran, P Sood, D Shiers, A Soundry / USA: C Correll See map for countries involved in this collaboration.

TRANSLATION This collaboration has brought together

clinicians and researchers concerned about the physical health of people with mental

illness. SIMPAQ is designed as tool which can be used within mental health services to

assist in obtaining a relevant exercise history and for evaluating physical activity

interventions. It identifies even small amounts of activity which is useful in

providing positive feedback to patients participating in physical activity

interventions and due to the brevity of the questionnaire it will not require much time or prove difficult for people with mental health problems to complete. It is freely

available for everyone to use. See www.simpaq.org

http://www.simpaq.org/


2013-2016: Survey of High Impact Psychosis WAve 2 (SHIP WAve 2) V Morgan, A Jablensky, G Watts, J Badcock, K Cox, N Stefanis, A Waterreus, J Griffith, P Di Prinzio, S Shah, T Major This NHMRC-funded study builds on a rare opportunity to collect longitudinal data on a population-based sample of people with psychotic illness, first assessed comprehensively between 2010 and 2013. Its objective is to fill the knowledge gap on cardiometabolic disease risk modification in people with psychotic illness. To achieve this, its aims are to: 1. Determine factors associated with

improvement and deterioration in cardiometabolic profiles in people with psychotic illness;

2. Examine impediments to the uptake of interventions for cardiometabolic disorders by people with psychotic illness; and

3. Work with services towards the development of a clinical service model for the implementation of targeted interventions within mental health services.

The study is following up, from 2013 to 2016, over 600 Western Australians with psychosis, thoroughly assessed in south metropolitan Perth as part of the 2010 National Survey of High Impact Psychosis (South Metro SHIP) and in 2012 in north metropolitan Perth in a SHIP expansion survey (North Metro SHIP). Follow up includes a face-to-face interview and a physical health assessment, augmented with data from health and prescribing registers.

TRANSLATION This observational study will provide unique

information from an unbiased cohort followed up over two time points. The

natural experimental design offers advantages over a clinical trial by capturing

the range of people with psychosis and assessing behaviour in real world individual and service contexts. As such, it has a very high utility value for mental health service

planning. In 2016, the SHIP Study group worked with Mental Illness Fellowship of Australia and Psychosis Australia Trust to

produce 5 infographic fact sheets on psychotic illness.

Survey of High Impact Psychosis: Findings on Physical Health of Participants with Psychotic Illness


2010 Australian National Survey of High Impact Psychosis (SHIP) V Morgan, A Jablensky, A Waterreus, J Griffith, P Di Prinzio, S Shah, in collaboration with the SHIP Study Group* The aims of this survey were: 1. To describe the prevalence and profile of

psychosis in Australia and 2. To identify factors associated with good

outcome in psychosis that are amenable to change and critical to recovery with the intention of informing policy development and service planning.

SHIP took place in 2010 at seven sites in five states across Australia: NSW, QLD, SA, VIC and WA. It included questions about: symptoms, utilisation of mental health and other services; perceived need; education; cognition; social participation (work and skill development; activities of daily living; family responsibilities; other social engagement and community integration); living circumstances; support networks; physical well-being (including a physical health assessment; physical activity; nutrition; risk factors for metabolic syndrome and cardiovascular disease; smoking); and drug and alcohol use. The survey was an initiative of psychosis researchers and clinicians across Australia in partnership with the Australia Government Department of Health and Ageing. This is the largest and most comprehensive assessment of psychotic disorders undertaken in Australia, and one of the most detailed undertaken internationally. The survey has provided a snapshot of people living with psychotic illness, the circumstances in which they live and the services they receive.

Among other findings, SHIP data demonstrated the very poor physical health of people with a psychotic disorder. The results also confirm that psychosis is associated with substantial and persistent disability. Apart from the psychiatric features of psychosis, these disorders impact on physical health, education, employment, and housing. Yet, in the face of disability, disadvantage, stigma and social isolation, people with psychotic disorder display resilience and tenacity. Over 60 papers have been produced from this survey to date, with many more in preparation. Key papers and reports from this study are available at:

http://www.psychiatry.uwa.edu.au/research/neru/publications/survey *Lead investigators of the SHIP Study Group that developed the survey protocol and continue to oversee the management and analysis of the survey data include: V Morgan (convenor), A Jablensky, A Waterreus, V Carr, D Castle, M Cohen, C Galletly, C Harvey, A Mackinnon, P McGorry, J McGrath, P Morgan, A Neil

TRANSLATION The survey was unique in that it included

data items not previously assessed contemporaneously and in depth in a large, unbiased sample. These included cognitive

tests, a physical health assessment with fasting blood tests, detailed socio-

demographic data, and data on the NGO sector. To date, there have been over 50

publications. Data are being used by government bodies, mental health services and NGOs to inform policy development,

resource distribution and service planning.

http://www.psychiatry.uwa.edu.au/research/neru/publications/survey

http://www.psychiatry.uwa.edu.au/research/neru/publications/survey


North Metro Survey of High Impact Psychosis (North Metro SHIP) V Morgan, A Waterreus, J Griffith, A Jablensky, P Di Prinzio, S Shah, , in collaboration with North Metropolitan Health Service Mental Health and the Mental Health Commission North Metro SHIP is an extension of the national SHIP survey, in WA North Metropolitan Health Service Mental Health (NMHS MH). Its aims were to: 1. Estimate the local prevalence of psychosis

in North Metropolitan Health Service (NMHS);

2. Describe the social and economic circumstances of people living with psychosis within NMHS, their mental and physical health profiles, and their use of services; and

3. Develop a local evidence base to help inform mental health policy development in NMHS and to enable service providers to develop services to meet specific local needs to the benefit of people living with psychosis, their family, friends, carers and the services supporting them.

The survey census month was March 2012 with interviews taking place from April 2012 to April 2013. North Metro SHIP was funded by the Mental Health Commission and the Western Australian Department of Health. NERU has been collaborating with Dr Milan Dragović and NMHS Clinical Research Centre in the production of Fact Sheets to inform policy and planning. A cost analysis using the data collection has also been completed.

http://www.psychiatry.uwa.edu.au/research/neru/publications/north-metro-ship

TRANSLATION This survey provided site-specific data to North Metropolitan Area Health Service

Mental Health, including costs, which are currently being used to identify gaps in

service planning and areas for policy development. Translation is through the

North Metro SHIP Committee.

Acting director NMHS Clinical Research Centre, Dr Milan Dragović




The 1997-98 Study of Low Prevalence (Psychotic) Disorders (LPDS) A Jablensky, V Morgan, A Waterreus, J Griffith, in collaboration with the LPDS Study Group* This was Australia's first national survey of psychosis. Of note, this survey included marginalised people not in contact with treatment services in its sampling and those solely in contact with private psychiatrists and GPs, in addition to those attending public mental health inpatient and outpatient services. In addition to generating point prevalence data for psychotic disorders in urban areas in Australia for the first time, the study was unique in ascertaining symptom profiles, rates of functional impairments and disability, indices of quality of life, substance use comorbidity, service utilisation patterns, and side effects of medication. Subsequent economic analyses provided estimates of direct and indirect costs associated with psychotic disorders. Key papers and reports from this study are available at:

http://www.psychiatry.uwa.edu.au/research/neru/publications/survey/the-1997-98-study-of-low-prevalence-psychotic-disorders *Lead investigators of the LPDS Study Group that developed the survey protocol and oversaw the collection and analysis of the survey data included: A Jablensky (convenor), J McGrath, H Herrman, D Castle, O Gureje, M Evans, V Carr, V Morgan, A Korten, C Harvey, A Waterreus

TRANSLATION For the first time, LPDS estimated the

prevalence and cost of psychotic illness in Australia, and established nationally representative benchmark data on

characteristics of those affected. A “best selling” product, still in high demand, was

the Diagnostic Interview for Psychosis, developed by the Western Australian

investigators.

http://www.psychiatry.uwa.edu.au/research/neru/publications/survey/the-1997-98-study-of-low-prevalence-psychotic-disorders




RESEARCH FUNDING RECEIVED/ 2012 ONWARDS ($)

See Appendices 1a and 1b for funding 1995-2011

Funding Source

Chief Investigators

Study Title 2012 2013 2014 2015 2016 2017 2018 2019 2020

WA Dept of Health

Morgan VA Medical and Health Research Infrastructure Fund 2015 (Round 20)

33,262

Royal Perth Hospital Medical Research Foundation Grant.

Morgan VA Jablensky A Di Prinzio P

Developmental lifecourse trajectories and schizophrenia.

19,508

Cockell Research Collaboration Award

Waterreus A Simple Physical Activity Questionnaire (SIMPAQ): an international validation study

10,585

WA Dept of Health


26,582

NHMRC APP1102628

Morgan VA McGrath J Galletly C Harvey C Castle D Cohen M Jablensky A Carr V Neil A Waterreus A

AIs: Mackinnon A, McGorry P, Tonkin A

An empirical framework for assessing mortality and morbidity in people with psychotic illness: 7-year follow-up and 10-year retrospective analysis of 2075 SHIP participants using linked mortality and health registers

216,131 111,131 141,537 136,537 146,537

WA Dept of Health


21,102

NH&MRC APP1080606

Morgan VA Jablensky A McNeil T Bjork J

AIs: McGrath J, Cannon M

Impact of social adversity on the developmental trajectory to mental illness: A study of a whole-population cohort of children at familial high-risk for psychotic disorders

177,825 199,632 162,825 127,273 122,273


Funding Source

Chief Investigators

Study Title 2012 2013 2014 2015 2016 2017 2018 2019 2020

NHMRC APP1064582

Jablensky A Moses E McCarthy N Melton P Dragovic M Morgan VA Badcock J Waters F

Schizophrenia under the genomic lens: next generation sequencing of Western Australian families with schizophrenia

423,437 178,437 358,437

UWA Faculty of Medicine, Dentistry and Health Sciences Near Miss Grant

Croft M Healthy pregnancy outcomes for mothers with severe mental illness needing psychotropic medications during pregnancy

70,000

Royal Perth Hospital Medical Research Foundation Infrastructure Funding

Morgan VA Round 2014 69,633

UWA Research Matching Funds

Morgan VA Psychosis Australia seed funding

30,000

WA Department of Health Merit Award

Croft M Morgan VA Jablensky A Duke J

The location, scope and utility for use in research purposes of the WA Health Department’s inpatient pharmacy data

5,000

NH&MRC APP1046729

Morgan VA Jablensky A Watts G Badcock J Cox K Stefanis N

AIs: Marwick P, Shymko G, Addis S, Velayudhan A

Overcoming barriers to improved physical health in people with severe mental illness

228,912 233,787 233,787 133,983

NHMRC Partnership Grant APP1028554

Austin M-P Sullivan E Highet N Morgan VA Mihalopoulos C Croft M

The Australian perinatal mental health reforms: using population data to evaluate their impact on service utilisation and related cost-effectiveness

NHMRC

beyondblue partnership

184,040

120,085

162,340

120,085

162,340

120,085

WA Dept of Health

Morgan VA North Metropolitan Survey of High Impact Psychosis Extension contract

167,625

WA Dept of Health

Morgan VA North Metropolitan Survey of High Impact Psychosis

Continuing from 2011

344,850 114,950


Funding Source

Chief Investigators

Study Title 2012 2013 2014 2015 2016 2017 2018 2019 2020

NH&MRC APP1002259

Jablensky A Morgan VA McNeil T Abel K Morgan F

Life course trajectories and neuro-psychiatric outcomes in an e-cohort of high risk children of mothers with psychosis

Continuing from 2011

304,701 191,073

TF McNeil. "Coulorado #2" 2016-17


PUBLICATIONS 2016

* A person may have publications in other research areas that have not been included here. Journal Articles Chambers GM, Randall S, Hoang VP, Sullivan EA, Highet N, Croft M, Mihalopoulos C, Morgan VA, Reilly N, Austin MP. The National Perinatal Depression Initiative: An evaluation of access to general practitioners, psychologists and psychiatrists through the Medicare Benefits Schedule. Australian and New Zealand Journal of Psychiatry, 2016, 50, 264–274.

Foley DL, Mackinnon A, Morgan VA, Watts GF, Castle DJ, Waterreus A, Galletly CA. Awareness of pre-diabetes or diabetes and associated factors in people with psychosis. Schizophrenia Bulletin, 2016, 42, 1280-1289.

Foley DL, Mackinnon A, Morgan VA, Watts GF, Castle DJ, Waterreus A, Galletly CA. Common familial risk factors for schizophrenia and diabetes mellitus. Australian and New Zealand Journal of Psychiatry, 2016, 50, 488–494.

Foley DL, Mackinnon A, Morgan VA, Castle DJ, Waterreus A, Galletly CA. Comorbid diabetes and depression in a national sample of adults with psychosis. Schizophrenia Bulletin. Accepted 2/11/2016.

Hahn L, Mackinnon A, Foley DL, Morgan VA, Waterreus A, Watts G, Castle DJ, Liu D, Galletly CA . Counting Up the Risks – How Common are Risk Factors for Morbidity and Mortality in Young People with Psychosis? Early Intervention in Psychiatry, 2016, Online Sept 2016.

Hahn L, Mackinnon A, Foley DL, Morgan VA, Waterreus A, Watts G, Castle D, Liu D, Galletly CA. The value of counting WHO-defined cardio-vascular risk factors for death and disability in a national sample of adults with psychosis. Schizophrenia Research. Online Sept 2016.

Hahn L, Mackinnon A, Foley DL, Morgan VA, Waterreus A, Watts G, Castle DJ, Liu D, Galletly CA. The role of arterial elasticity and cardiovascular peripheral resistance as clinically relevant indices of health status in people with psychosis. Schizophrenia Research, 2016, online: 10.1016/j.schres.2016.11.046

Hall CM, Bryant KA, Haskard K, Major T, S, Calver MC, Factors determining the home ranges of pet cats: A meta-analysis. Biological Conservation, 2016, 203, 313-320.

Laugharne J, Waterreus AJ, Castle DJ, Dragovic M. Screening for the metabolic syndrome in Australia: a national survey of psychiatrists’ attitudes and reported practice in patients prescribed antipsychotic drugs. Australasian Psychiatry, 2016, 24, 62-6.

Lin A, Di Prinzio P, Young D, Jacoby P, Whitehouse A, Waters F, Jablensky A, Morgan VA, Academic performance in children of mothers with schizophrenia and other severe mental illness, and risk for subsequent development of psychosis: a population-based study. Schizophrenia Bulletin. Online 30 April 2016 doi:10.1093/schbul/sbw042.

Liu D, Myles H, Foley DL, Watts G, Morgan VA, Castle DJ, Waterreus A, Mackinnon A, Galletly CA. Risk factors for obstructive sleep apnoea are prevalent in people with psychosis and correlate with impaired social functioning and poor physical health. Frontiers in Psychiatry, 2016, 7 (139): DOI:10.3389/fpsyt.2016.00139.

McCarthy NS, Melton PE, Ward SV, Allan SM, Dragovic M, Clark ML, Morar B, Rubio J P, Blangero J, Badcock JC, Morgan VA, Moses EK. Jablensky A. Exome array analysis suggests an increased variant burden in families with schizophrenia. Schizophrenia Research, 2016, online: 10.1016/j.schres.2016.12.007

Morgan VA, Morgan F, Galletly C, Shah, S, Valuri G and Jablensky A. Sociodemographic, clinical and childhood correlates of adult violent victimisation in a large, national survey sample of people with psychotic disorders. Social Psychiatry and Psychiatric Epidemiology, 2016, 51, 269–279.

Morgan VA, Waterreus A, Carr V, Castle D, Cohen M, Harvey C, Galletly C, Mackinnon A, McGorry P, McGrath J, Neil A, Saw S, Badcock J, Foley D, Waghorn G, Coker S, Jablensky A. Responding to challenges for people with psychotic illness: Updated evidence from the Survey of High Impact Psychosis—SHIP. Australian and New Zealand Journal of Psychiatry, 2016, Accepted 25 Oct 2016.


Neil A, Carr V, Mackinnon A, Morgan VA. Evidence or ideology? Let the Debate Continue… More evaluation please! Australian and New Zealand Journal of Psychiatry 2016, 50, 495–6.

Rosenbaum S, Tiedemann A, Stanton R, Parker A, Waterreus A, Curtis J, Ward PB. Implementing evidence-based physical activity interventions for people with mental illness: an Australian perspective. Australasian Psychiatry 2016, 24, 49-54.

Rosenbaum S, Ward PB on behalf of the International Working Group. The Simple Physical Activity Questionnaire. The Lancet Psychiatry. 2016 Jan 1;3(1):e1.

Siskind, D, Harris, M, Phillipou, A, Morgan, VA, Waterreus, A, Galletly, C, Carr, V, Harvey, C. Castle D. Clozapine users in Australia: their characteristics and experiences of care based on data from the 2010 National Survey of High Impact Psychosis. Epidemiology and Psychiatric Sciences, 2016, online July 2016 DOI: 10.1017/S2045796016000305.

Suetani S, Waterreus A, Morgan VA, Foley D, Galletly C, Badcock J, Watts G, McKinnon A, Castle D, Saha S, Scott J, McGrath J. Correlates of physical activity in people living with psychotic illness in Australia. Acta Psychiatrica Scandinavica, 2016, 134, 129–137.

Sweeney S, Air T, Zannettino L, Shah SS, Galletly C. Gender Differences in the Physical and Psychological Manifestation of Childhood Trauma and/or Adversity in People with Psychosis. Frontiers in Psychology 2015 (corrected version 2016), 6(1768).

Valuri G, Morgan F, Jablensky A, Morgan VA. Impact of social disadvantage and parental offending on rates of offending among offspring of women with severe mental illness. Australian and New Zealand Journal of Psychiatry, 2016, accepted 15 Dec 2016

Waterreus A, Di Prinzio P, Watts G, Castle D, Galletly C, Morgan VA. Metabolic syndrome in people with a psychotic illness: Is cannabis protective? Psychological Medicine, 2016, 46, 1651-1662.

Reports Amanda L. Neil AL, Carr V, Mackinnon A, Morgan VA for the Survey of High Impact Psychosis (SHIP) Study Group in collaboration with Psychosis Australia Trust. The Economic Impacts of Psychosis: Unlocking the Black Box. July 2016

Morgan VA. on behalf of the SHIP Study Group with Psychosis Australia Trust. Insights 1. Mental health of people with psychosis. Fact sheet from the Survey of High Impact Psychosis. 2016

Morgan VA. on behalf of the SHIP Study Group with Psychosis Australia Trust. Insights 2. Physical health + people with psychosis. Fact sheet from the Survey of High Impact Psychosis. 2016

Morgan VA. on behalf of the SHIP Study Group with Psychosis Australia Trust. Insights 3. Services + support for people with psychosis. Fact sheet from the Survey of High Impact Psychosis. 2016

Morgan VA. on behalf of the SHIP Study Group with Psychosis Australia Trust. Insights 4. Employment + people with psychosis. Fact sheet from the Survey of High Impact Psychosis. 2016

Morgan VA. on behalf of the SHIP Study Group with Psychosis Australia Trust. Insights 5. Social isolation + people with psychosis. Fact sheet from the Survey of High Impact Psychosis. 2016

Published Abstracts Morgan VA. Di Prinzio P, Valuri G, Croft M, Shah S, McNeil T, Jablensky A. A life course perspective on familial and environmental risks for schizophrenia using a Western Australian e-Cohort. European Psychiatry, 2016, 33, Supplement S52


ORAL CONFERENCE PRESENTATIONS 2016

Major T, Croft M, Morgan V, Di Prinzio P, McNeil T, Jablensky A. Reproductive pathology and perinatal outcomes for infants of women with schizophrenia and other psychotic disorders: a population study. Australasian Marce Society for Perinatal Mental Health Conference, Melbourne , 25-28 September 2016.

Major T, Austin MP, Hutcherson J, Chatterton ML, Mihalopoulos C, Sullivan E, Chambers G, Reilly N, Highet N, Croft M, Morgan V. Patterns of obstetric, psychiatric and other inpatient service utilization among women giving birth in Australia. Australasian Marce Society for Perinatal Mental Health Conference, Melbourne , 25-28 September 2016.

Morgan VA. A whole-person perspective on recovery for people with psychotic illness. Data from the Australian national psychosis survey. 2016 International Congress on Schizophrenia, Chennai, India, 8-10 Sep 2016

Morgan VA. Di Prinzio P, Valuri G, Croft M, Shah S, McNeil T, Jablensky A. A life course perspective on familial and environmental risks for schizophrenia using a Western Australian e-Cohort. Paper in symposium on: Lifespan development of schizophrenia and how the treatments improve outcome. European Congress of Psychiatry, Madrid 12-15 March 2016.

Neil A, Carr V, Mackinnon A, Morgan VA The costs of psychosis in Australia: a comparison of the average annual costs and cost profiles for five subpopulations. TheMHS Conference, Auckland, 23-26 August 2016.

Neil A, Carr V, Mackinnon A, Morgan VA. Robust and sensitive health state utility values can be obtained for psychotic disorders using the AQoL-4D: findings from the Second Australian National Survey of Psychosis. TheMHS Conference, Auckland, 23-26 August 2016.

POSTER PRESENTATIONS 2016

Di Prinzio P, Morgan VA, Björk J, Croft M, Jablensky A / McNeil T. Investigating the association of maternal severe mental illness and exposure to obstetric complications with rates of intellectual disability. Schizophrenia International Research Society Annual Meeting, Florence, 2-6 April 2016

Lin A, Di Prinzio P, Young D, Jacoby P, Whitehouse A, Waters F, Jablensky A, Morgan VA. Academic performance in children of mothers with schizophrenia and other severe mental illness, and risk for the development of psychosis: a population-based study. Schizophrenia International Research Society Annual Meeting, Florence, 2-6 April 2016

Neil A, Carr V, Mackinnon A, Waterreus A, Stain H, Hanlon M-C, Korn S, Morgan VA. Health Related Quality of Life in Schizophrenia and Other psychoses: AQoL-4D Findings from the Second Australian National Survey of Psychosis. Schizophrenia International Research Society Annual Meeting, Florence, 2-6 April 2016

Richards J, Rosenbaum S, Bauman A, Carraro A, Gaughran F, Gerber M, Schuch F, Stubbs B, Vancampfort D, Waterreus A, Ward P. Assessing physical activity among people experiencing mental illness: feasibility and validity of the Simple Physical Activity Questionnaire (SIMPAQ) The 6th International Congress on Physical Activity and Public Health, Bangkok, Thailand, 16-19 November 2016.


OTHER TALKS AND PRESENTATIONS 2016

Vera Morgan Invited speaker. The Australian National Survey of High Impact Psychosis (SHIP). Looking backwards - Moving forward. National Mental Health Commission, Sydney 11 May 2016

Vera Morgan Recovery for people with psychotic illness. WA Primary Health Alliance: Lunchtime Seminar, Perth, 9 November 2016

Vera Morgan Recovery for people with psychotic illness. Using National survey data to inform a whole-person perspective. Royal Perth Bentley Group: Academic Program, Perth, 25 October 2016

Vera Morgan A whole-person perspective on recovery for people with psychotic illness. Data from the Australian national psychosis survey. WA Primary Health Alliance Mental Health Week Symposium, Perth, 10 October 2016

Vera Morgan Body and mind – physical comorbidities in severe mental illness. Medical Journal of Australia Mental Health Continuing Professional Development, Perth, 20 August 2016

Vera Morgan Revisiting “high risk” for psychosis: A developmental life course perspective on familial and environmental risks for psychotic illness. Fiona Stanley Hospital Psychiatry Grand Round, 16 August 2016

Vera Morgan Australian National Survey of High Impact Psychosis (SHIP) 2010. Western Australian Primary Health Alliance, Perth, 12 August 2016

Vera Morgan Revisiting “high risk” for psychosis: A developmental life course perspective on familial and environmental risks for psychotic illness. Neuroepidemiology Seminar. Telethon Kids Institute, 10 August 2016

Giulietta Valuri Impact of social, environmental and familial factors on rates of offending in offspring of mothers with severe mental illness. Stirling Catchment CMHS Clinical Learning Series 2016. Osborne CMHS Osborne Park Hospital, 15 June 2016.

Giulietta Valuri Impact of social disadvantage and parental offending on rates of criminal offending among offspring of women with severe mental illness. RPH-MRF Research Day. Royal Perth Hospital, 19 October 2016


POSTGRADUATE STUDENTS 2016

Student Degree Topic Start date NERU

supervisor Supervisor(s)

C. Harrison PhD Epidemiology of cardiovascular disease risk factors in the psychiatric population of WA

Part-time 2009

Vera Morgan VA Morgan (co-ordinating) M Dragovic AJ Jablensky J Laugharne

G. Valuri PhD Criminal offending, victimization and schizophrenia

Part-time 17 Sept 2010

Vera Morgan VA Morgan (co-ordinating) FH Morgan AJ Jablensky

A Waterreus PhD The effects of cannabis use on physical health, cognitive function and functional outcome by people with a psychotic illness

Part-time 12 Mar 2015

Vera Morgan VA Morgan (co-ordinating) J Badcock AJ Jablensky M Martin-Iversen

P. Di Prinzio M.Biostats Investigating the association of maternal severe mental illness and exposure to obstetric complications with rates of intellectual disability

Part-time Sept 2011

Vera Morgan J Björk


VISITORS 2016

Prof Megan Galbally

Foundation Chair in Perinatal Psychiatry Murdoch University / University of Notre Dame / Fiona Stanley Hospital

18/02/2016

Prof Thomas McNeil

Emeritus Professor, Unit for Psychiatric Epidemiology, Skånes University Hospital, Lund, Sweden

22/02/2016-26/02/2016

Maddie Di Prinzio. “Crystal” 2013


RESEARCH COLLABORATIONS AND ACTIVITIES 2016

International External Collaborators Affiliation NERU

collaborators Area of collaboration Outcomes 2016

Prof Tom McNeil University of Lund, Sweden

All Developmental pathways for the children of women with severe mental illness

Advice on changes to the McNeil-Sjöström Scale

Paper in early neurodevelopmental outcomes in progress

Joint NHMRC grant 2015-2019

Prof Jonas Björk University of Lund, Sweden

All Developmental pathways for the children of women with severe mental illness

Paper on early neurodevelopmental outcomes in progress


Prof Jonas Björk University of Lund, Sweden

P Di Prinzio Biostatistics Statistical supervisor for Masters of Biostatistics workplace project.

Prof Johan Lyhagen Dr Katrin Kraus

Department of Statistics, Uppsala University Sweden

P Di Prinzio Applications of Structural Equation Modelling

Advice on approach to use of SEM with large, mixed measurement, longitudinal dataset of social adversity exposures

Prof Mary Cannon Institute of Psychiatry, Royal College of Surgeons in Ireland

V Morgan Adversity and psychosis Joint NHMRC grant 2015-2019

Prof Kathryn Abel University of Manchester V Morgan A Jablensky

Developmental pathways for the children of women with severe mental illness

Investigators on successful European Research Council Consolidator Grant 2015 (K Abel person support)

International Physical Activity Measurement Group

Australia: P Ward (Chair), S Rosenbaum (co-Chair), J Curtis, J Richards, A Bauman / Belgium: D Vancampfort / Brazil: F Schuch, F Moraleida Canada: G Faulkner / Denmark: H Speyer / Finland: S Eskelinen / Italy: A Carraro / Nigeria: R Uwakwa /Switzerland: M Gerber/ UK: B Stubbs, M Ussher, F Gaughran, P Sood, D Shiers, A Soundry / USA: C Correll

A Waterreus Measuring Physical Activity in people with Mental Health Problems.

Establishing an international consortium for a multinational effort to develop and validate a new questionnaire

Joint publication

Prof Vidje Hansen Dr Ingunn Skre

Institute for Psychology, University of Tromsø, Norway

A Jablensky V Morgan

Validation of Norwegian translation of Diagnostic Interview for Psychosis.

Visiting PhD student Connie Moen from University of Tromsø


National External Collaborators Affiliation NERU


Dr Simon Rosenbaum A/Prof Philip Ward Justin Richards

University of New South Wales

Anna Waterreus

Physical activity questionnaire development

Joint publication

SIMPAQ study

International meeting

Prof John McGrath University of QLD V Morgan A Jablensky

Risk factor epidemiology Joint NHMRC grant 2015-2019

Psychosis Australia Trust Psychosis Australia Trust

V Morgan A Jablensky

Psychosis research network

Executive committee member

Publication of summary fact sheets

Survey of High Impact Psychosis (SHIP) Study Group: Prof Vaughan Carr Prof David Castle Prof Cherrie Galletly Prof Carol Harvey Prof Assen Jablensky Prof John McGrath Prof Andrew Mackinnon Prof Pat McGorry Prof Vera Morgan (Chair) Dr Amanda Neil Dr Paul Morgan A/Prof Anna Waterreus

Universities and health services in WA, NSW, QLD, SA, VIC

V Morgan A Jablensky A Waterreus J Griffith

Survey of High Impact Psychosis (SHIP)


Joint publications

Other SHIP investigators: Dr Helen Stain (UK) Dr Debra Foley (VIC) Dr Geoff Waghorn (QLD) Prof Johanna Badcock (WA) Ms Suzy Saw (ACT)

V Morgan A Jablensky A Waterreus

Survey of High Impact Psychosis (SHIP)

Joint publications

Prof Andrew Tonkin (VIC) Monash University V Morgan A Jablensky A Waterreus

Follow-up to the Survey of High Impact Psychosis (SHIP)


SANE Australia V Morgan Survey of High Impact Psychosis (SHIP)

Membership of Clinical Expert Advisory Group


State External Collaborators Affiliation NERU


Prof Megan Galbally Andrew Lewis Timothy Fairchild

Kym Guelfi

School of Psychology and Exercise Science, Murdoch University

UWA School of Sports Science

V Morgan A Waterreus P Di Prinzio

Measurement tools (SIMPAQ; obstetric complications)

Grant collaboration

Anna Ferrante James Boyd

PHRN Centre for Data Linkage, Curtin University

V Morgan A Jablensky A Waterreus

Record linkage Joint NHMRC grant 2014-2016

A/Prof Frank Morgan School of Population Health

V Morgan G Valuri A Jablensky

Victimisation and offending in people with psychosis

Joint publication

Prof David Preen Erin Kelty

Geoff Smith Theresa Williams

UWA School of Population Health

WA Centre for Mental Health Policy Research

V Morgan Early Intervention in Psychosis study

Analyses for joint publications

Dept of Health Western Australia (North Metro and Clinical Research Centre)

North Metro SHIP Committee

V Morgan A Waterreus

Operational epidemiology

North Metro SHIP Committee member

Fact sheets for service providers

North/South Metro data sharing agreement

WA Primary Health Alliance WA Primary Health Alliance

V Morgan Operational epidemiology

Data provision for service planning

North/South Metro data sharing agreement

Several presentations

Dept of Health Western Australia (North and South Metro)

Dept of Health Western Australia

V Morgan A Waterreus J Griffith A Jablensky

Longitudinal study following up physical health of SHIP participants

SHIP WAve2 study

Prof Gerald Watts A/Prof Kay Cox

Prof J Badcock

UWA School of Medicine

Centre for Clinical Research in Neuropsychiatry

V Morgan A Waterreus J Griffith A Jablensky

SHIP SHIP WAve2

Joint publications


Prof A Jablensky* Prof J Badcock UWA Centre for Genetic Origins of Health and Disease

Centre for Clinical Research in Neuropsychiatry

V Morgan WA Family Study of Schizophrenia

Joint publications


* A Jablensky appears as both external and internal NERU collaborator for those projects that straddle his dual roles as Senior Scientific Consultant: Neuropsychiatric Epidemiology Research Unit and Director: Centre for Clinical Research in Neuropsychiatry


STAFF: AWARDS AND PRIZES 2016

SIRS Travel Award to attend the 5th Biennial Schizophrenia International Research Society Conference, Florence 2016. Out of 263 submissions, a total of 49 recipients from 41 countries were given this distinguished award.

Patsy Di Prinzio


STAFF: CONFERENCE ORGANISING COMMITTEES 2016

Member, Program Committee Australasian Schizophrenia Conference 2016-2018

Vera Morgan

STAFF: EDITORIAL COMMITTEES 2016

Member, Advisory Board Australian and New Zealand Journal of Psychiatry

Vera Morgan

Member, Editorial Board Social Psychiatry and Psychiatric Epidemiology

Vera Morgan


STAFF: FORMAL OFFICES & COMMITTEE MEMBERSHIP 2016

Honorary Member Information Technology Reference Group, Ngala, WA Maxine Croft

Chair National Survey of High Impact Psychosis (SHIP) Study Group Vera Morgan

Member North Metropolitan Health Service SHIP Committee Vera Morgan

Member Intellectual Disability Exploring Answers (IDEA) Advisory Council and Ethics Committee

Vera Morgan

Member Schizophrenia International Research Society 2016 – 2018 Awards Committee

Vera Morgan

Member UWA Faculty of Medicine, Dentistry and Health Sciences, Faculty Research Committee

Vera Morgan

Member UWA School of Psychiatry and Clinical Neurosciences: Research and Publications Committee

Vera Morgan

Member Australian Schizophrenia Research Bank: Access Committee Vera Morgan

Member Australian Rotary Health Research Committee Vera Morgan

Member Mental Health Needs of WA Reception Prisoners Steering Group

Vera Morgan

Member Psychosis Australian Trust Research Committee Vera Morgan

Scientific and Research Advisor

Meeting for Minds Vera Morgan

Member SANE Australia Clinical Expert Advisory Group Vera Morgan

Member National Survey of High Impact Psychosis (SHIP) Study Group Anna Waterreus

Member International SIMPAQ Working Group Anna Waterreus


STAFF: CURRENT PROFILE

Maxine CROFT BAppSc PhD

EPIDEMIOLOGIST / BIOLOGIST: Neuropsychiatric Epidemiology Research Unit/ Honorary Research Fellow, Centre for Child Health Research, University of Western Australia

+61 8 9224 0287

[email protected]

Maxine Croft is a computer scientist and epidemiologist who has been a consultant to WHO on database design. As a consultant to the Federal government on diabetes research, she proposed the (now accepted) recording of Medicare numbers on PBS prescriptions. Her doctoral research resulted in creation of the WA Twin Child Health registry and she uses linked population data to measure risk of recurrence of reproductive outcomes. She has modified an electronic version of the McNeil Sjöström scoring system to include a broader range of maternal diseases. This Perth version will also include longitudinal measures of maternal chronic disease. Research interests • Perinatal epidemiology

• Schizophrenia

• Longitudinal measures of maternal health

• Obstetric complications

• Database management

Patsy Di PRINZIO BAppSci BSc(Hons) MBiostat

BIOSTATISTICIAN: Neuropsychiatric Epidemiology Research Unit

+61 8 9224 0231

[email protected]

Patsy Di Prinzio is a biostatistician with high level mathematical, statistical, computing and problem solving skills as well as excellent written communication abilities. She completed her Masters of Biostatistics in 2016. Currently she is working towards combining mixed measurement indicators of social adversity, some of which have longitudinal, multilevel or censoring aspects, into a clinically meaningful scale. She has recently completed a documentation and validation review of the unit’s electronic application of the McNeil Sjöström Scale for Obstetric Complications. Her previous experience includes consulting in applied statistics in private, government, and university sectors, as well as teaching experience in government and university. Research interests • Applied statistics

• Epidemiology of schizophrenia and other psychotic disorders

• Automation of data management, analysis and results presentation as a linked process

Structural Equation Modelling


Jenny GRIFFITH RN RMHN BAAppSc(Nursing) GradDipArtsCounselling PGDipMentalHealthNursing

DEPUTY COORDINATOR SHIP Wave2 / MENTAL HEALTH CLINICAL RESEARCH NURSE: Neuropsychiatric Epidemiology Research Unit

+61 8 9224 0347

[email protected]

Jenny Griffith is Deputy Coordinator for the Survey of High Impact Psychosis (SHIP) Wave2. She was Deputy Coordinator for North Metro SHIP and the WA site Coordinator for National SHIP. Jenny was an interviewer in the 1998 National Survey of Low Prevalence (Psychotic) Disorders. Since 2004, she has also managed the collection of qualitative mental health data in the Pathways study, including the review of clinical casenotes, to complete the Diagnostic Interview for Psychosis (DIP), the Children’s Checklist and Life Histories. Research interests • Life histories of people with severe mental illness

• Metabolic syndrome in people with severe mental illness

• Role of mental health nurses in research

Assen JABLENSKY MD DMedSc FRCPsych

FRANZCPsych

SENIOR SCIENTIFIC CONSULTANT: Neuropsychiatric Epidemiology Research Unit / DIRECTOR: Centre for Clinical Research in Neuropsychiatry

+61 8 9224 0290

[email protected]

Assen Jablensky completed his medical degree and training as a psychiatrist in Bulgaria and the UK, and has worked as a researcher and clinician in Switzerland (WHO, Geneva), the US (Stanford University) and, since 1993, Australia, where he is director of the Centre for Clinical Research in Neuropsychiatry of the University of Western Australia in Perth. He has over 290 publications, including articles in peer-reviewed journals, book chapters and monographs. He has been award the Strömgren Prize and medal for psychiatric epidemiology; the Australasian Society for Psychiatric Research Founders Medal, the Organon Senior Research Award, and several other distinctions including Honorary Fellowship of the Royal College of Psychiatrists (UK). Research interests • psychiatric epidemiology

• genetics of schizophrenia

• classification of mental disorders


Ashleigh LIN BSc(hons) MClinNeuropsychology PhD

VISITING RESEARCH FELLOW / POST-DOCTORAL FELLOW: Telethon Kids Institute

+61 8 9489 7772 [email protected]

Ashleigh Lin is a NHMRC Early Career Fellow at the Telethon Kids Institute in Perth. She completed her training as a clinical neuropsychologist and her PhD in Melbourne before working as a research fellow in the UK. Ashleigh’s research interest is in youth mental health, with a particular focus on risk for schizophrenia. Ashleigh is undertaking a component of her post-doctoral research with the NERU team, examining educational outcome as a predictor for psychotic illness. Research interests • Youth mental health

• Risk for schizophrenia

• Clinical staging of mental illness

• Neurocognition

Taryn MAJOR BSci BEng MAppStat MBiostat

BIOSTATISTICIAN: Neuropsychiatric Epidemiology Research Unit

+61 8 9224 0291

[email protected]

Taryn Major is a biostatistician who completed her Master of Biostatistics in 2015. She is currently working on record linked data across two projects: reproductive pathology and obstetric complications in WA mothers with schizophrenia and other psychotic disorders; and patterns of psychiatric services utilisation among women giving birth in WA and NSW. In 2016, Taryn also joined the SHIP team, beginning the process of data harmonisation across waves. Until October 2016, Taryn also worked as a consultant statistician at Data Analysis Australia, where she has responsibility for complex statistical analyses across a variety of industries and applications. Her areas of expertise include modelling, survey design and analysis, forecasting and biostatistics. Research interests • Applied statistics / Biostatistics

• Epidemiology of schizophrenia and other psychotic disorders

• Reproductive pathology and mental health services utilisation


Vera MORGAN BA GradDipEd MSocSc PhD

HEAD: Neuropsychiatric Epidemiology Research Unit / DEPUTY DIRECTOR: Centre for Clinical Research in Neuropsychiatry

+61 8 9224 0235

[email protected]

Vera Morgan is a psychiatric epidemiologist with a special interest in the epidemiology of schizophrenia and other psychotic disorders. Her current program of research focuses on environmental (especially obstetric) and genetic contributions to the risk of schizophrenia, as well as physical health comorbidity, including metabolic syndrome and cardiovascular disease, in people with psychotic illness. Her expertise is in the area of epidemiological data design, management and analysis, and she has wide experience using record-linked population health and criminological databases. She was project director and convenor of the Technical Advisory group for the 2010 national psychosis survey. Her professional roles have included: President of the Australasian Society for Psychiatric Research, Vice-President of the Australasian Epidemiological Association and Chair of the Research Committee of the Mental Health Council of Australia. Research interests • Epidemiology of schizophrenia and other psychoses

• Risk factor epidemiology

• Cardiometabolic disease and psychotic illness

• Intellectual disability and psychotic disorders

• Criminal offending and mental illness

•

Giulietta VALURI BBus GradDipEpi

EPIDEMIOLOGIST / CRIMINOLOGIST: Neuropsychiatric Epidemiology Research Unit

+61 8 9224 0288

[email protected]

Giulietta Valuri is a computer scientist and an epidemiologist who has worked in injury prevention research and with linked WA population databases in both criminology (patterns of offending) and mental health. Her research has included validating mental health diagnoses and studying patterns of offending in people with a mental illness. Her current research focuses on measuring and mapping children’s health status using WA data from linked statewide health registers and constructing offending profiles for these children using criminal offending data. Her expertise is in the areas of database management and design, and analytical techniques. Research interests • Epidemiology of schizophrenia and other psychotic

disorders

• High risk children of parents with severe mental illness

• Criminal offending and mental illness


Anna WATERREUS DipNursingStudies NZRN GradDipClinEpid

COORDINATOR FOR SHIP WAve2: Neuropsychiatric Epidemiology Research Unit

+61 8 9347 6438

[email protected]

Anna Waterreus is a Nurse who has a Post Graduate Diploma in Clinical Epidemiology and has been involved in psychiatric research for the last 25 years. Currently she is the Coordinator for the NHMRC Survey of High Impact Psychosis WAve2. She also had a coordinating role in the first and second Australian surveys of psychosis (the Low Prevalence (Psychotic) Disorders Survey and the Survey of High Impact Psychosis (SHIP). She is a member of an International working group which has developed a new physical activity questionnaire (SIMPAQ) which will undergo validation in 2016.Previously she worked in Epidemiology and General Practice at the Institute of Psychiatry, London. Research interests • Metabolic syndrome and physical health

• Cannabis and mental health

• Mental health surveys

• Mental health nursing

Stephanie Gee (BA)

Senior Administrative Officer:

School of Psychiatry and Clinical Neurosciences

+61 8 9224 0290

[email protected]

Stephanie has worked in administration in the University sector for nearly 20 years.

Her primary focus is on the administration of teaching programs and student clinical placements. She also

provides administrative support to NERU and the wider School for travel and financial matters.


APPENDICES

TF McNeil. “Perth” 2014


APPENDIX 1a. Research Funding

2004-2011 ($)

Funding CIs Study Title 2004 2005 2006 2007 2008 2009 2010 2011

WA Dept of Health

Morgan VA North Metropolitan Survey of High Impact Psychosis

550,000

Also funded

in 2012, 2013

NH&MRC APP1002259

Jablensky A Morgan VA McNeil T Abel K Morgan F

Life course trajectories and neuropsychiatric outcomes in an e-cohort of high risk children of mothers with psychosis

274,701

Also funded

in 2012, 2013

Aust. Govt. Dept of Health and Ageing

Morgan VA Jablensky A

National survey of high impact psychosis (SHIP): Phase 3

3,300,000 1,928,097 148,904



National survey of high impact psychosis (SHIP): Phase 2

606,903

NH&MRC #513874

Jablensky A Kalaydjieva L Segal M Badcock J Wiltshire S Price G Morgan VA

Memory synaptic plasticity and gene networks in schizophrenia

113,500 454,250 242,750 272,750

March of Dimes Research Foundation #12-FY07-224

Jablensky A Morgan VA Bower C Zubrick S Croft M

A population-based study of obstetric, developmental and neuropsychiatric outcomes in the offspring of women with severe mental disorders. Round 2

45,772 93,500 93,500



Scoping a national survey of high impact psychosis (SHIP): Phase 1

78,006 78,006

Dept of Health of WA

Morgan VA Jablensky A Smith G Williams T

Psychiatric inpatient services database 1990-2006

30,909

Dept of Health of WA

Morgan VA Jablensky A Smith G Williams T

High Users of psychiatric inpatient services 1990-2006

21,818

NH&MRC #458702

Jablensky A Morgan VA

Children of parents with mental illness: a population-based study

329,950 294,000 131,125

NH&MRC Jablensky A Kalaydjieva L Badcock J Kendler K Morgan, VA Riley B

Genetics of cognitive impairment in schizophrenia 295,000 260,272 235,000


Funding CIs Study Title 2004 2005 2006 2007 2008 2009 2010 2011

Criminology Research Council

Morgan F Morgan VA Jablensky A Ferrante A Valuri G

Schizophrenia and offending: area of residence and the impact of social disorganisation and disadvantage

41,934

March of Dimes Research Foundation

Jablensky A Morgan VA Bower C Zubrick S

A population-based study of obstetric, developmental and neuropsychiatric outcomes in the offspring of women with severe mental disorders. Round 1

55,806 154,386 52,309

NH&MRC Jablensky A Morgan VA

Fetal origin of adult disease? A population-based study of the offspring of women with severe mental disorders

172,500 187,500 82,875

APPENDIX 1b. Research Funding

1995-2003 ($)

Funding CIs Study Title 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003

UWA Small Research Grant

Morgan VA Psychiatric morbidity and mental retardation: A Western Australian record linkage study

14,000

Commonwealth Dept of Health and Aged Care

Jablensky A Follow-up to the Low Prevalence Disorders study

60,000 20,000

Stanley Foundation

Jablensky A Zubrick S Bower C Morgan VA Preston N

Pathways of risk from conception to disease: A population-based study of the offspring of women with bipolar disorder and schizophrenia

111,307 110,426

NHMRC (PHRDC) Jablensky A Castle D Morgan F Ferrante A

Criminal behaviour as an outcome in schizophrenia 78,242 66,152 53,311

NHMRC (PHRDC) Holman D Jablensky A Fazio S Bass J

Population linkage studies of preventable comorbidity in people with mental illness

34,632 75,849 78,353

Commonwealth Dept of Health and Aged Care

Jablensky A Low Prevalence (Psychotic) Disorders study

523,000

Stanley Foundation

Jablensky A Zubrick S Bower C Castle D

Reproductive pathology in women with schizophrenia and bipolar affective disorder: An epidemiological & clinical study

40,343 65,141

Royal Perth Hospital Medical Research Foundation

Jablensky A Castle D Page A Petterson B

Influenza epidemics and incidence of CNS disorders in Western Australia

18,311


APPENDIX 2. SELECTED PUBLICATIONS 1995-2015 (Epidemiology)

2015 Journal Articles

Badcock JC, Clark M, Pedruzzi R, Morgan VA, Jablensky A. Intact speed of processing in a community-based sample of adults with high schizotypy: A marker of reduced psychosis risk? Psychiatry Research, 2015, 228, 531–537.

Badcock JC, Shah S, Mackinnon A, Stain HJ, Galletly C, Jablensky A, Morgan VA. Loneliness in psychotic disorders and its association with cognitive function and symptom profile. Schizophrenia Research, 2015, 169, 268–273.

Foley DL, Mackinnon A, Morgan VA, Watts GF, Shaw JE, Magliano DJ, Castle DJ, McGrath JJ, Waterreus A, Galletly CA. Cardiovascular risk indicator associations in adults with psychosis and adults in a national comparator sample. Australian and New Zealand Journal of Psychiatry, 2015, 49, 714-723.

Foley DL, Mackinnon A, Morgan VA, Watts GF, Castle DJ, Waterreus A, Galletly CA. Effect of age, family history of diabetes, and antipsychotic drug treatment on risk of diabetes in people with psychosis: a population-based cross-sectional study. The Lancet Psychiatry, 2015, 2, 1092-8.

Hasan A, Falkai P, Wobrock T, Lieberman J, Glenthoj B, Gattaz WF, Thibaut F, Moller HJ. & WFSBP Task Force on Treatment Guidelines for Schizophrenia (incl. Jablensky A). World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia. Part 3: Update 2015 Management of special circumstances: Depression, Suicidality, substance use disorders and pregnancy and lactation. World Journal of Biological Psychiatry, 2015, 16, 142-70.

Jablensky A. (2015). Schizophrenia or schizophrenias? The challenge of genetic parsing of a complex disorder." American Journal of Psychiatry, 2015, 172(2), 105-107.

Mancuso S, Morgan VA, Mitchell P, Berk M, Young A, Castle D. A comparison of schizophrenia, schizoaffective disorder, and bipolar disorder: results from the Second Australian National Psychosis Survey, Journal of Affective Disorders, 2015, 172, 30-37.

McGorry PD, on behalf of the Australian Early Psychosis Research Network Writing Group (incl. Morgan VA). Australian Early Psychosis Research Network: national collaboration, international competitive advantage. Med J Aust, 2015, 202, 170-1.

O’Donnell M, Maclean M, Sims S, Morgan VA, Leonard H, Stanley F. Maternal mental health and risk of child protection involvement: Mental health diagnoses associated with increased risk. Journal of Epidemiology & Community Health, 2015, 69,1175-83.

Power B, Dragovic M, Badcock J, Morgan VA, Castle D, Jablensky A, Stefanis N. No additive effect of cannabis on cognition in schizophrenia. Schizophrenia Research, 2015, 168, 245–251.

Saha S, Morgan VA, Castle D, Silove D, McGrath J. Socio-demographic and clinical correlates of migrant status in adults with psychotic disorders: Data from the Australian Survey of High Impact Psychosis. Epidemiology and Psychiatric Sciences, 2015, 24, 534-541.

Sodhi-Berry N, Knuiman M, Alan J, Morgan VA, Preen D. Pre- and post-sentence mental health service use by a population cohort of older adult offenders (≥45 years) in Western Australia Social Psychiatry and Psychiatric Epidemiology, 2015, 50, 1097-1110.

Sodhi-Berry N, Knuiman M, Alan J, Morgan VA, Preen D. Pre-sentence mental health service use predicts post-sentence mortality in a population cohort of first-time adult offenders. Social Psychiatry and Psychiatric Epidemiology, 2015, 50, 109-124.

Sodhi-Berry N, Knuiman M, Preen D, Alan J, Morgan VA. Predictors of post-sentence mental health service use in a population cohort of first-time adult offenders in Western Australia. Criminal Behaviour and Mental Health, 2015, 25, 355–374.


Published abstracts

Morgan VA. Morgan F. Galletly C, Valuri G, Shah S. Sociodemographic, clinical and childhood determinants of victimisation in a large, national survey sample of adults with severe mental illness. Schizophrenia Bulletin 2015, 41 Suppl. 1, 148.

Morgan VA, Di Prinzio P, Shah S, Valuri G, Croft M, McNeil T, Jablensky A. Timing and impact of social stressors in a cohort of children at familial high risk for psychotic illness. Paper in symposium on: At risk from conception: epidemiological evidence for early risk factors for psychosis. Schizophrenia Bulletin 2015, 41 Suppl. 1, 148.

Reports

Davison S, Fleming J, Butler T, Morgan VA, Petch E, Morgan F, Rock D, Jones J, Wright M, Mitchell M, Janca A. Mental health and substance use problems in Western Australian prisoners. Report from the Health and Emotional Wellbeing Survey of Western Australian Reception Prisoners, 2013. Perth, Western Australian Department of Health, 2015.

Neil A. and Morgan VA. North Metropolitan Health Service Survey of High Impact Psychosis (NM-SHIP): Costs. Report to North Metropolitan Health Service Mental Health, 2015.


Brameld KJ, Dye DE, Maxwell S, Brisbane JM, Glasson EJ, Goldblatt J, O’Leary P. The Western Australian Family Connections Genealogical Project: detection of familial occurrences of single gene and chromosomal disorders. Genetic Testing and Molecular Biomarkers, 2014, 18, 77-82.

Foley D, Mackinnon A, Morgan VA, Watts G, McGrath J, Castle D, Waterreus A, Galletly C. Predictors of type 2 diabetes in a nationally representative sample of adults with psychosis. World Psychiatry, 2014, 13, 176-183.

Jablensky A, Waters F. RDoC: a roadmap to pathogenesis? World Psychiatry, 2014, 13, 43-44.

Hahn LA, Galletly CA, Foley DL, Mackinnon A, Watts GF, Castle DJ, Waterreus A, Morgan VA. Inadequate fruit and vegetable intake in people with psychosis. Australian and New Zealand Journal of Psychiatry, 2014, 48, 70-79.

Morgan VA, McGrath J, Jablensky A, Badcock JC, Waterreus A, Bush R, Carr V, Castle D, Cohen M, Galletly C, Harvey C, Hocking B, McGorry P, Neil A, Saw S, Shah S, Stain H, Mackinnon A. Psychosis prevalence and physical, metabolic and cognitive comorbidity. Data from the second Australian national survey of psychosis. Psychological Medicine, 2014, 44, 2163-2176.

Morgan VA, Valuri, G, Croft M, Shah S, Di Prinzio P, Griffith J, McNeil T, Jablensky A. Longitudinal, whole-population data examining pathways of risk from conception to disease: the Western Australian schizophrenia high-risk e-Cohort. Open Health Data, 2014, 2(1): e4, DOI: http://dx.doi.org/10.5334/ohd.aj.

Neil A, Carr V, Mihalopoulos C, Mackinnon A, Lewin T, Morgan VA. What difference a decade? The costs of psychosis in Australia in 2000 and 2010: comparative results from the first and second Australian National Surveys of Psychosis. Australian and New Zealand Journal of Psychiatry, 2014, 48, 237-248.

Neil A, Carr V, Mihalopoulos C, Mackinnon A, Morgan VA. Costs of psychosis in 2010: findings from the second Australian National Survey of Psychosis. Australian and New Zealand Journal of Psychiatry, 2014, 48, 169-182.


Power B, Stefanis N, Dragovic M, Jablensky A, Castle D, Morgan VA. Age at initiation of amphetamine use and age at onset of psychosis: The Australian Survey of High Impact Psychosis. Schizophrenia Research, 2014, 152, 300-2.

Raudino A, Carr V, Bush R, Saw S, Burgess P, Morgan VA. Patterns of health service utilisation. Results from the second Australian national survey of psychosis (SHIP). Australian and New Zealand Journal of Psychiatry, 2014, 48, 341-351.

Sara G, Luo L, Carr V, Raudino A, Green M, Laurens M, Dean K, Cohen M, Burgess P, Morgan VA. Comparing algorithms for deriving psychosis diagnoses from longitudinal administrative clinical records. Social Psychiatry and Psychiatric Epidemiology, 2014, 49:1729–1737.

Shah S, Mackinnon A, Galletly C, Carr V, McGrath J, Stain H, Castle D, Harvey C, Sweeney S, Morgan VA. Prevalence and impact of childhood abuse in people with a psychotic illness. Data from the second Australian national survey of psychosis. Schizophrenia Research 2014, 159:20-26.

Sodhi-Berry N, Preen D, Alan J, Knuiman M, Morgan VA. Pre-sentence mental health service use by adult offenders in Western Australia: Baseline results from a longitudinal whole-population cohort study. Criminal Behaviour and Mental Health, 2014, 24, 204–221.

Stefanis N, Dragovic M, Power B, Jablensky A, Castle D, Morgan VA. The effect of drug use on the age at onset of psychotic disorders in an Australian cohort. Schizophrenia Research, 2014, 156:211-216.

Published abstracts

Foley D, Mackinnon A, Morgan VA, Watts G, Shaw J, Magliano D, Castle D, McGrath J, Waterreus A, Galletly C. Best buys for early intervention to improve cardiometabolic health in adults with psychosis: an Australian perspective. Early Intervention in Psychiatry, 2014, 8, Supplement 1, 26

Galletly C, Foley D, Mackinnon A, Watts G, Shaw J, Magliano D, Castle D, McGrath J, Waterreus A, Morgan VA. Risk factors for death and disability in young people with psychosis. Schizophrenia Research 2014, 153, Supplement 1 S19.

Galletly C, Hahn L, Foley D, McKinnon A, Watts G, Castle D, Liu D, Waterreus A, Morgan VA. Determinants of poor diet among a large sample of people living with a psychotic illness. Schizophrenia Research 2014, 153, Supplement 1 S316.

Morgan VA, Badcock J, Waterreus A, Galletly C, Shah S, Mackinnon A. The role of cognition in metabolic disturbance in people with psychotic illness: Novel data from a large population prevalence survey. Schizophrenia Research 2014, 153, Supplement 1 S223.

Shah S, Jablensky J, Croft M, Valuri G, Di Prinzio P, Abel K, Morgan VA. Risk of mortality in offspring of mothers with psychosis: a Western Australian whole-of-population cohort study. Schizophrenia Research 2014, 153, Supplement 1 S67.

Waterreus A, Di Prinzio P, Galletly C, Castle D, Watts G, Morgan VA. Metabolic syndrome in people with psychosis: Is cannabis protective? Schizophrenia Research 2014, 153, Supplement 1 S381.



Foley D, Mackinnon A, Watts G, Shaw J, Magliano D, Castle D, McGrath J, Waterreus A, Morgan VA, Galletly C. Cardiometabolic risk indicators that distinguish adults with psychosis from the general population, by age and gender. PLoS ONE, 2013, 8, e82606.

Morgan VA. Strategies for improving employment outcomes for people with psychosis. Commentary on: Severe mental illness and work – What can we do to maximise employment opportunities for individuals with psychosis? Australian and New Zealand Journal of Psychiatry, 2013, 47, 486-487.

Morgan VA, Morgan F, Valuri G, Ferrante A, Castle D and Jablensky A. A whole-of-population study of the prevalence and patterns of criminal offending in schizophrenia and other psychiatric disorders. Psychological Medicine, 2013, 43, 1869 - 1880

O’Donnell M, Anderson D, Morgan VA, Nassar N, Leonard H, Stanley F. Trends in pre-existing mental health disorders among parents of infants born in Western Australia from 1990 to 2005. Medical Journal of Australia, 2013, 198, 485-488.

Stefanis NC, Milan Dragovic M, Power BD, Jablensky A , Castle D, Morgan VA. Age at initiation of cannabis use predicts age at onset of psychosis: The 7-8 year trend. Schizophrenia Bulletin, 2013, 39, 251-254. Books and Chapters

Morgan VA, Keefe R, Kahn RS, Malhotra AK, Meyer-Lindenberg A, Mueser KT, Nikolich K, Rössler W, Spaulding W, Sritharan S and Wyke T. What is necessary to enhance development and utilization of treatment? In Silverstein SM, Moghaddam B, Wykes T(eds). Schizophrenia: Evolution and Synthesis. Strüngmann Forum Reports, vol 13, J.Lupp, series ed. Cambridge, MIT Press, 2013, pages 273-305.

Published abstracts

McGrath J, Galletly C, Waterreus A, Jablensky A, Mackinnon A, Carr V, Bush R, Castle, D, Cohen M, Harvey C, Stain H, Neil A, McGorry P, Hocking B, Shah S, Badcock J, Saw S, Morgan VA, Comorbid physical illness in those with psychotic disorders; the Australian National Psychosis Survey. Schizophrenia Bulletin 2013, 39 Suppl 1, 35.

Morgan VA, Di Prinzio P, Shah S, Valuri G, Croft M, Jablensky A. The association between social adversity and psychosis in a whole-of-population cohort of high risk offspring of mothers with psychotic disorders. Schizophrenia Bulletin 2013, 39 Suppl 1, 71

Morgan VA, Waterreus A, Jablensky A, Mackinnon A, McGrath J, Carr V, Bush R, Castle, D, Cohen M, Harvey C, Galletly C, Stain H, Neil A, McGorry P, Hocking B, Shah S, Badcock J, Saw S. Psychosis prevalence, profile, comorbidity and cognition. Novel data from the Australian National Psychosis Survey. Schizophrenia Bulletin 2013, 39 Suppl 1, 71. Other publications

Morgan VA, Marwick P, Waterreus A, Jablensky A, Rock D, Sultan L, Shah S, Di Prinzio P. North Metropolitan Health Service Survey of High Impact Psychosis (North Metro SHIP). Report to North Metropolitan Health Service Mental Health and Mental Health Commission. November 2013

Waterreus A on behalf of the SHIP Study Group: SHIP GP Summary Report, 2013.



Galletly C, Foley D, Waterreus A, Watts G, Castle D, McGrath J; Mackinnon A, Morgan VA. Cardiometabolic risk factors in people with psychotic disorders: the second Australian survey of psychosis. Australian and New Zealand Journal of Psychiatry, 2012, 46, 753-761.

Morgan VA, Croft M, Valuri G, Zubrick S, Bower C, McNeil T and Jablensky A. Intellectual disability and other neuropsychiatric outcomes in high risk children of mothers with schizophrenia, bipolar disorder and unipolar major depression. British Journal of Psychiatry, 2012, 200, 282-289.

Morgan VA, Waterreus A, Jablensky A, Mackinnon A, McGrath J, Carr V, Bush R, Castle D, Cohen M, Harvey C, Galletly C, Stain H, Neil A, McGorry P, Hocking B, Shah S, Saw S. People living with psychotic illness in 2010. The second Australian national survey of psychosis. Australian and New Zealand Journal of Psychiatry, 2012, 46,735-753.

Waghorn G, Saha S, Harvey C, Morgan VA, Waterreus A, Bush R, Castle D, Galletly C, Stain H, Neil A, McGorry P, McGrath J. “Earning and learning” in those with psychotic disorders: the second Australian survey of psychosis. Australian and New Zealand Journal of Psychiatry, 2012, 46, 774-785.

Waterreus A, Morgan VA, Castle D, Galletly C, Jablensky A, Di Prinzio P, Shah S. Medication for psychosis - consumption and consequences. The second Australian national survey of psychosis. Australian and New Zealand Journal of Psychiatry, 2012, 46, 762-773. Books and Chapters

Meadows G, Harvey C, Morgan VA. Singh B. Mental disorder in Australia. In Meadows G, Farhall J, Fossey E, Grigg M, McDermott F, Singh B (eds) Mental Health in Australia (3rd ed) Oxford University Press, 2012, pages 237-263.

Published abstracts

Galletly CA, Foley DL, Waterreus A, Watts GF, Castle D, McGrath J, Mackinnon A & Morgan VA (2012). ABSTRACT. High rates of cardiometabolic risk factors in people with psychotic disorders. Schizophrenia Research 136, Supplement 1, S308.

Morgan VA, Waterreus A, Jablensky A, Mackinnon A, McGrath JJ, Carr V, Bush R, Castle D, Cohen M, Harvey C, Galletly C, Stain H, Neil AL, McGorry P, Hocking B & Saw S (2012). ABSTRACT. Novel data from a large population prevalence survey: A unique opportunity to inform psychosis research directions and mental health reform. Schizophrenia Research 136, Supplement 1, S73

Reports and other publications

Morgan V. National psychosis survey: mapping use of services. New Paradigm 2012, Autumn, 30-36.

Waterreus A on behalf of the SHIP Study Group: SHIP Participant Summary Report, 2012.

Waterreus A on behalf of the SHIP Study Group: SHIP NGO Summary Report, 2012.



Kendler KS, Jablensky A (2010) Kraepelin's concept of psychiatric illness. Psychological Medicine 2011, 41(6), 1119-26

Morgan VA, Valuri G, Croft M, Griffith J, Shah S, Young D and Jablensky A. Pathways of risk from conception to disease: The Western Australian Schizophrenia High Risk e-Cohort. International Journal of Epidemiology, 2011, 40, 1477-1485.

Books and Chapters

Abel KM & Morgan VA. Mental illness, women, mothers and their children. In: Tsuang MT, Tohen M, Jones PJ (eds). Psychiatric Epidemiology (3rd Edition). New York. John Wiley & Sons, 2011, pp 483-515

Jablensky A. Diagnosis and revision of the classification system. In: W Gaebel (ed) Schizophrenia: Current Science and Clinical Practice. Wiley-Blackwell, 2011, ch 1:1-30.

Published abstracts

Morgan V, Jablensky A, Waterreus A, Bush R, Carr V, Castle D, Cohen M, Galletly C, Harvey C, Hocking B, Mackinnon A, McGorry P, McGrath J, Neil A, Saw S, Stain H. The Australian national survey of the epidemiology of psychosis: aims and preliminary findings. Schizophrenia Bulletin 2011, 37, Suppl 1, 57.

Reports

Morgan VA, Waterreus A, Jablensky A, Mackinnon A, McGrath J, Carr V, Bush R, Castle D, Cohen M, Harvey C, Galletly C, Stain H, Neil A, McGorry P, Hocking B, Shah S, Saw S. People living with psychotic illness 2010. Report on the second Australian national survey. Canberra, Australian Government Department of Health and Ageing, November, 2011.


Croft ML, Morgan VA, Read A, Jablensky AV. Recorded pregnancy histories of the mothers of singletons and the mothers of twins: a longitudinal comparison. Twin Research and Human Genetics. 2010, 13(6) Invited paper.

Jablensky A. The diagnostic concept of schizophrenia: its history, evolution, and future prospects. Dialogues in Clinical Neuroscience 2010, 12(3):271-87.

Jablensky A. Psychiatry in crisis? Back to fundamentals. World Psychiatry 2010, 9(1):29.

Henderson S, Jablensky A. The Lundby Study. Aust N Z J Psychiatry. 2010 Jan;44(1):1-3

Loughland C, Draganic D, McCabe K, Richards J, Nasir A, Allen J, Catts S, Jablensky A, Henskens F, Michie P, Mowry B, Pantelis C, Schall U, Scott R, Tooney P, Carr V. Australian Schizophrenia Research Bank: a database of comprehensive clinical, endophenotypic and genetic data for aetiological studies of schizophrenia. Aust N Z J Psychiatry. 2010 Nov;44(11):1029-35.

Midford R, Young DJ, Chikritzhs T, Playford D, Kite E, Pascal R (2009). The Effect of Alcohol Sales and Advertising Restrictions on a Remote Australian Community. Drugs: Education, Prevention & Policy. 2010, 17(1), 21-41.

Morgan VA and Jablensky AV. From inventory to benchmark: quality of psychiatric case registers in research. British Journal of Psychiatry. 2010, 197, 8-10.

Rossi A, Morgan V, Amaddeo F, Sandri M, Grigoletti L, Maggioni F, Ferro A, Rigon E, Donisi V, Vailati Venturi V, Goria F, Skre I, Tansella M, and Jablensky A. Diagnosing psychotic disorders: reliability and applications of the Diagnostic Interview for Psychosis (DIP) Italian version. Epidemiologia e Psichiatria Sociale 2010, 19, 33-43.

Selten J-P and Morgan VA. Prenatal Exposure to Influenza and Major Affective Disorder. Bipolar Disorders. 2010, 12, 753–754.

Selten J-P, Frissen A, Lensvelt-Mulders G, Morgan VA. Schizophrenia and 1957 Pandemic of Influenza: Meta-Analysis. Schizophrenia Bulletin, 2010, 36, 219-228.

Young DJ, Bebbington A, de Klerk N, Bower C, Nagarajan L, & Leonard H (2011). The relationship between MECP2 mutation type and health status and service use trajectories over time in a Rett syndrome population. Research in Autism Spectrum Disorders,( 2010) 5(1), 442-449. IF: 2.267.


Published abstracts

Morgan VA on behalf of the SHIP Technical Advisory Group and Project Implementation Steering Group: Morgan V, Jablensky A, Waterreus A, Bush R, Carr V, Castle D, Cohen M, Galletly C, Harvey C, McGorry P, McGrath J, Stain H, Hocking B, Mackinnon A, Neil A, Saw S. Revisiting social breakdown syndrome: The Australian National Survey of High Impact Psychosis (SHIP). Schizophrenia Research 2010, 117, 314.

Selten J-P, Frissen A, Lensvelt-Mulders G, Morgan V. Schizophrenia and 1957 pandemic of influenza: Meta-analysis. Schizophrenia Research 2010, 117, 430.


Downs J, Young D, de Klerk N, Bebbington A, Baikie G, Leonard H. Impact of scoliosis surgery on activities of daily living in females with Rett syndrome. J Pediatr Orthop. 2009 Jun, 29(4) 369-74.

Jablensky A. Towards ICD-11 and DSM-V: issues beyond 'harmonisation'. British Journal of Psychiatry 2009, 195(5):379-81.

Jablensky A. A meta-commentary on the proposal for a meta-structure for DSM-V and ICD-11. Psychological Medicine 2009, 39(12): 2099-2103 (comment/reply).

Morgan VA and Jablensky AV. Invited author’s reply. Re: Dual Diagnosis Quandries. Letter. British Journal of Psychiatry 2009, 194(5), 469-470.

Swanson PB, Kane RT, Pearsall-Jones JG, Swanson CF, Croft ML. How couples cope with the death of a twin or higher order multiple. Twin Research and Human Genetics, 2009, Vol 12(4), 392-402.

Waterreus A. D E Laugharne JDE. Screening for the metabolic syndrome in patients receiving antipsychotic treatment: a proposed algorithm. Medical Journal of Australia, 2009, 190(4), 185-189.

Young DJ, Levy F, Martin NC, Hay DA. Attention deficit hyperactivity disorder: a Rasch analysis of the SWAN Rating Scale. Child Psychiatry Hum Dev. 2009, 40(4), 543-559.

Books and Chapters

Jablensky A. Course and outcome of schizophrenia and their prediction. In M Gelder, N Andreasen, JJ López-Ibor (ed) The New Oxford Textbook of Psychiatry, 2nd edition. Oxford University Press, 2009.

Jablensky A. Epidemiology of schizophrenia. In M Gelder, N Andreasen, JJ López-Ibor (ed) The New Oxford Textbook of Psychiatry, 2nd edition. Oxford University Press, 2009.


Jablensky A. Worldwide burden of schizophrenia. In BJ Sadock, VA Sadock, P Ruiz (ed) Kaplan and Sadock’s Comprehensive Textbook of Psychiatry. Wolters Kluwer / Lippincott Williams & Wilkins, 2009.

Morgan VA, McGrath J, Hultman C, Zubrick S, Bower C, Croft M, Valuri G, Jablensky AV. The Offspring of Women with Severe Mental Disorder. In Newnham JP, Ross MG (eds). Early Life Origins of Human Health and Disease. Basel. Karger, 2009.

Published abstracts

Jablensky, AV. The future of high risk research. Schizophrenia Bulletin 2009. 35 Suppl. 1: 73-74

Morgan VA, Zubrick S, Bower C, Croft M, Valuri G, Griffith J, Jablensky, A. Environmental and familial determinants of adverse neuropsychiatric outcomes in high risk children of mothers with schizophrenia and other psychoses. Schizophrenia Bulletin 2009, 35 Suppl. 1: 76.


Abel K, Webb R and Morgan V. Taking the Spotlight off Schizophrenia. eLetter. British Journal of Psychiatry http://bjp.rcpsych.org/cgi/eletters/193/4/311 (10 Dec 2008).

Jablensky, A.V. and Sartorius, N. What did the WHO Studies really find? Schizophrenia Bulletin, 2008 34(2):253-5.

Hauck, Y., Rock, D.J.T., Jackiewicz, T. and Jablensky, A.V. Healthy babies for mothers with serious mental illness: a case management framework for mental health clinicians. International Journal of Mental Health Nursing, 2008, 17(6), 383-391.

Morgan V, Leonard H, Bourke J, Jablensky A. Intellectual disability co-occurring with schizophrenia and other psychiatric illness: a population-based study. British Journal of Psychiatry, 2008 193, 364–372.

Morgan F, Morgan V, Clare J, Valuri G, Woodman R, Ferrante A, Castle D, Jablensky A. Schizophrenia and offending: area of residence and the impact of social disorganisation and urbanicity. Trends and Issues in Crime and Criminal Justice 2008, 365.

Morgan V, Castle D, Jablensky A. Do women express and experience psychosis differently from men? Epidemiological evidence from the Australian National Study of Low Prevalence (Psychotic) Disorders. Australian and New Zealand Journal of Psychiatry, 2008, 42, 74-82.

Davis SR, Shah SM, McKenzie DP, Kulkarni J, Davison SL, Bell RJ. Dehydroepiandrosterone sulfate levels are associated with more favourable cognitive function in women. Journal of Clinical Endocrinology & Metabolism, 2008: 93: 801-808. Books and Chapters

Farmer, A.E. and Jablensky, A.V. Current approaches to classification. In R Murray, P Hill, P McGuffin (ed) The Essentials of Postgraduate .Psychiatry, 4th ed, Cambridge University Press

Castle D and Morgan V. Epidemiology of schizophrenia. in Mueser, K and Jeste, D (eds.) The Clinical Handbook of Schizophrenia, Guilford Press, New York (2008).


Reports

Hauck Y, Rock D, Jackiewicz T & Jablensky A (2008) Healthy Babies for Mothers with Serious Mental Illness: A case management framework for mental health clinicians - Clinicians’ Manual. North Metropolitan Area Health Service (Mental Health), WA Department of Health.

Hauck Y, Rock D, Jackiewicz T & Jablensky A (2008) Healthy Babies for Mothers with Serious Mental Illness: A case management framework for mental health clinicians - Framework Overview. North Metropolitan Area Health Service (Mental Health), WA Department of Health.

Published abstracts

Croft ML, Griffith J, Morgan V, Valuri G, Jablensky AV. High risk children of women with schizophrenia and other mental illness: instruments for assessing risks and identifying outcomes. Schizophrenia Research 2008. 102, Issues 1-3, Supp 2: 164.

Croft ML, Morgan V, Valuri G, Bower J, Zubrick S, Jablensky A. Obstetric risk factors for schizophrenia: identifying neurological damage and/or hypoxia in infants using population databases. Australian and New Zealand Journal of Psychiatry. 2008, 42, Suppl. 2.

Morgan V, Zubrick S, Bower C, Croft M, Valuri G, Jablensky A. Why is the risk of intellectual disability elevated in the children of mothers with schizophrenia and other psychoses? Schizophrenia Research 2008, 102 Suppl 2, 167.

Morgan V, Zubrick S, Bower C, Croft M, Valuri G, Griffith J, Jablensky A. What impact do obstetric complications have on the risk of adverse psychiatric outcomes for the high risk children of mothers with schizophrenia and other psychoses? Schizophrenia Research 2008, 102 Suppl 2, 167-168

Morgan V, Zubrick S, Bower C, Croft M, Valuri G, Jablensky A Determinants of elevated risk of intellectual disability in children of mothers with psychoses. Australian and New Zealand Journal of Psychiatry. 2008, 42, Suppl. 3, A49.

Morgan V, Zubrick S, Bower C, Croft M, Valuri G, Griffith J, Jablensky A Determinants of adverse psychiatric outcomes for high risk children of mothers with schizophrenia and other psychoses: The role of environmental and familial risk factors. Australian and New Zealand Journal of Psychiatry. 2008, 42, Suppl. 2, A24.

Valuri GM, Croft ML, Morgan VA, Jablensky A. The high risk children of mothers with schizophrenia and other severe mental illness: modelling risk from conception to disease. Schizophrenia Research , 2008, 102, Suppl. 2, 169.


Jablensky, A. Does psychiatry need an overarching concept of “mental disorder”? World Psychiatry, 2007, 6, 157-158.

Jablensky, A. Living in a Kraepelinian world: Kraepelin’s impact on modern psychiatry. History of Psychiatry, 2007, 18, 381-388.

Jablensky, A. and Morgan, V. Book review: Psychiatric Epidemiology. Searching for the causes of mental disorders, Psychological Medicine, 2007, 37, 905-908.

Tait RJ. Hulse GK. Waterreus A. Flicker L. Lautenschlager NT. Jamrozik K. Almeida OP. Effectiveness of a smoking cessation intervention in older adults. Addiction. 2007, 102, 148. Books and Chapters

Jablensky A. Schizophrenia and related psychoses. In D. Bhugra, K. Bhui (eds) Textbook of Cultural Psychiatry. Cambridge University Press, 2007, 207-223.

Mendelson G, Jablensky A. What does psychiatry encompass? In S Bloch, B Singh (eds) Foundations of Clinical Psychiatry, 3rd edition, Melbourne University Press, 2007, 69-90.



Almeida OP. Waterreus A. Hankey GJ. Preventing depression after stroke: Results from a randomized placebo-controlled trial. Journal of Clinical Psychiatry. 2006, 67, 1104-9.

Castle, D.J., Jablensky, A., McGrath, J.J., Carr, V., Morgan, V., Waterreus, A., Valuri, G., Stain, H., McGuffin, P. and Farmer, A. The diagnostic interview for psychoses (DIP): development, reliability and applications, Psychological Medicine, 2006, 36, 69-80.

Davis SR, Goldstat R, Papalia M, Shah S, Kulkarni J, Donath S, Bell RJ. Effects of aromatase inhibin on sexual function and wellbeing in postmenopausal women treated with testosterone: a randomized placebo controlled trial. Menopause, 2006 13(1) 37-45.

Jablensky, A. Historical dictionary of psychiatry, Psychological Medicine, 2006, 36, 277-278.

Jablensky A. The epidemiology of schizophrenia, ed by RM Murray, P. Jones, E. Susser, J van Os, M Cannon (book review). Australian and New Zealand Journal of Psychiatry, 2006, 40, 503.

Morgan, V., Korten, A. and Jablensky, A. Modifiable risk factors for hospitalization among people with psychosis: evidence from the National Study of Low Prevalence (Psychotic) Disorders, Australian and New Zealand Journal of Psychiatry, 2006, 40, 683-690.

Morgan, V.A. and Jablensky, A.V. Exploring the role of reproductive pathology in the etiology of schizophrenia: What happens when mothers with schizophrenia give birth?, Directions in Psychiatry, 2006, 26, 1-15.

Shah, S, Bell, RJ, Davis SR. Homocysteine and cognitive decline after menopause. Climacteric, 2006 9 (2) 77-87.

Shah S. Bell RJ, Savage G, Ades R, Papalia M-A, Kulkarni J, Donath S, Davis S. Testosterone aromatization and cognition in women: a randomized placebo controlled trial. Menopause, 2006 13 (4) 600-608.


Jablensky, A. Categories, dimensions and prototypes: Critical issues for psychiatric classification, Psychopathology, 2005, 38, 201-205.

Jablensky, A. The long and winding road of schizophrenia research, Epidemiologia E Psichiatria Sociale, 2005, 14, 179-183.

Jablensky, A. Boundaries of mental disorders, Current Opinion in Psychiatry, 2005, 18, 653-658.

Jablensky, A.V., Morgan, V., Zubrick, S.R., Bower, C. and Yellachich, L.A. Pregnancy, delivery, and neonatal complications in a population cohort of women with schizophrenia and major affective disorders, American Journal of Psychiatry, 2005, 162, 79-91.

Kaiser, R., Lohrer, F., Morgan, V. and Hambrecht, M. Changes in the pattern of substance abuse after the onset of psychosis, Australian and New Zealand Journal of Psychiatry, 2005, 39, 467-472.

Morgan, V.A., Mitchell, P.B. and Jablensky, A.V. The epidemiology of bipolar disorder: sociodemographic, disability and service utilization data from the Australian National Study of Low Prevalence (Psychotic) Disorders, Bipolar Disorders, 2005, 7, 326-337.

Rossi, A., Morgan, V., Amaddeo, F., Sandri, M., Tansella, M. and Jablensky, A. Psychiatric out-patients seen once only in South Verona and Western Australia: a comparative case-register study, Australian and New Zealand Journal of Psychiatry, 2005, 39, 414-422.

Valuri G, Stevenson M, Finch C, Hammer B, Elliot B. The Validity of a Four Week Self-Recall of Sports Injuries. Injury Prevention. 2005, 11, 135-137. Books and Chapters

Castle, D.J. and Jablensky, A.V. Diagnosis and classification in psychiatry, Core Psychiatry, ed Wright, P, Stern, J & Phelan, M., Edinburgh, Elsevier Saunders, 2005, 507-515.

Jablensky, A. Disease and health in the cultural context, Understanding the Global Dimensions of Health, ed Gunn, S.W.A., Mansourian, P.B., Davies, A.M., Piel, A., Sayers, B.McA., New York, Springer Science & Business Media Inc., 2005, 231-239 Reports

Ferrante AM, Loh NSN, Maller MG, Valuri GM, Fernandez JA. Crime and Justice Statistics for Western Australia: 2004. Statistical Report. Crime Research Centre, University of Western Australia, Dec 2005.



Almeida OP. Waterreus A. Spry N. Flicker L. Martins RN. One year follow-up study of the association between chemical castration, sex hormones, beta-amyloid, memory and depression in men. Psychoneuroendocrinology. 2004, 29, 1071-81.

Blagg H & Valuri G. Aboriginal Community Patrols in Australia: Self-Policing, Self Determination and Security. Policing & Society 2004, 14, 313-328.

Blagg H & Valuri G. Self-policing and community safety: the work of Aboriginal Community Patrols in Australia. Current Issues in Criminal Justice 2004, 15, 205-219.

Glasson, E.J., Bower, C., Petterson, B., de Klerk, N., Chaney, G. and Hallmayer, J.F. Perinatal factors and the development of autism: a population study, Archives of General Psychiatry, 2004, 61, 618-627.

Hansen J, Alessandri, PT, Croft ML, Burton, PR, de Klerk NH. The Western Australian Register of childhood multiples: Effects of questionnaire design and follow-up protocols on response rates and representativeness. Twin Research 2004, 7, 149-161.

Jablensky A. Researching psychiatry in Western Australia. Australian and New Zealand Journal of Psychiatry 2004, 38, 306-315.

Jablensky A. The syndrome – an antidote to spurious comorbidity? World Psychiatry 2004, 3, 24-25.

Kavanagh, D.J., Waghorn, G., Jenner, L., Chant, D.C., Carr, V., Evans, M., Herrman, H., Jablensky, A. and McGrath, J.J. Demographic and clinical correlates of comorbid substance use disorders in psychosis: multivariate analyses from an epidemiological sample, Schizophrenia Research, 2004, 66, 115-124. Reports

Croft M and Ferrante A. A Review of the Data Matching Processes of the Cervical Cytology Registry for the Western Australian Cervical Cancer Prevention Program. Commissioned by the Women’s Cancer Prevention Program of the WA Department of Health 2004.

Fernandez JA, Ferrante AM, Loh NSN, Maller MG, Valuri GM. Crime and Justice Statistics for Western Australia: 2003. Statistical Report. Crime Research Centre, University of Western Australia, Dec 2004.

Leonard H, Petterson B, Bourke J, Morgan V, Glasson E, Bower C. Inaugural report of the idEA database - Intellectual disability in Western Australia. Perth Western Australia, Institute for Child Health Research, 2004.


Jablensky, A.V. and Kalaydjieva, L.V. Genetic epidemiology of schizophrenia: phenotypes, risk factors, and reproductive behaviour, American Journal of Psychiatry, 2003, 160, 425-429.

Kendell, R.V. and Jablensky, A. Distinguishing between the validity and utility of psychiatric diagnoses, American Journal of Psychiatry, 2003, 160, 4-12.

Lawrence, D.M., Holman, C.D.J., Jablensky, A.V. and Hobbs, M.S.T. Death rate from ischaemic heart disease in Western Australian psychiatric patients 1980-1998, British Journal of Psychiatry, 2003, 182, 31-36.

Morgan, V., Janca, A. and Jablensky, A. Psychotic disorders in Australia: patients respond to national survey results, European Psychiatry, 2003, 18, 142.

Morgan, V. Two-phase sampling designs for rare outcomes, Australasian Epidemiologist, 2003, 10, 2-3.

Books and Chapters

Jablensky, A. The epidemiological horizon, Schizophrenia, ed Hirsch, S.R., Weinberger, D.R., England, Blackwell Publishing, 2003, 203-231.

Jablensky, A. Diagnosing schizophrenia: a personal view, Schizophrenia, ed Maj, M., Sartorius, N., England, John Wiley & Sons Ltd, 2003, 58-61. Reports

Blagg H, Valuri G. An Overview of Night Patrol Services in Australia. Attorney-General’s Department, Crime Prevention Unit. Mar 2003.



Castle D, Morgan V, Jablensky A. Antipsychotic use in Australia: the patients’ perspective. Australian and New Zealand Journal of Psychiatry 2002, 36, 633-641.

Castle D, Morgan V. Attitudes to depot antipsychotics. Letter. British Journal of Psychiatry 2002, 180, 187-188.

Croft ML, Read AW, de Klerk N, Hansen J, Kurinczuk JJ. Population based ascertainment of twins and their siblings, born in Western Australia 1980 to 1992, through the construction and validation of a maternally linked data base of siblings. Twin Research 2002, 5, 317-23.

Dunn JC. Almeida OP. Barclay L. Waterreus A. Flicker L. Latent semantic analysis: a new method to measure prose recall. Journal of Clinical & Experimental Neuropsychology. 2002, 24, 26-35.

Gureje O, Herrman H, Harvey C, Morgan V, Jablensky A. The Australian National Survey of Psychotic Disorders: profile of psychosocial disability and its risk factors. Psychological Medicine 2002, 32, 639-647.

Jablensky A. Research methods in psychiatric epidemiology: an overview. Australian and New Zealand Journal of Psychiatry 2002, 36, 297-310.

Jablensky A. The classification of personality disorders: Critical review and need for rethinking. Psychopathology 2002, 35, 112-116.

Morgan V. Psychiatric Epidemiology. Guest editorial. Australasian Epidemiologist 2002, 9 (2), 1-2.

Morgan V. What can record linkage contribute to psychiatric epidemiology? Australasian Epidemiologist 2002, 9 (2), 25-29.

Morgan V, Janca A, Jablensky A. National study of psychotic disorders in Australia: Feedback from individuals with psychosis. The Hong Kong Journal of Psychiatry 2002, 12, 8-12. Books and Chapters

Jablensky, A., & Kendell, R. E. Criteria for assessing a classification in psychiatry. In M. Maj (Ed.), The Future of Psychiatric Diagnosis and Classification. World Psychiatric Association. 2002.

Jablensky, A., & Cooper, J. E. Classification of dementia and other organic conditions in ICD-10. In J. R. M. Copeland, M. T. Abou-Saleh, & D. G. Blazer (Eds.), Principles and Practice of Geriatric Psychiatry (Vol. 2nd edition). Chichester: Wiley, 2002.

Reports

Morgan V, Castle D, Jablensky A. The use of psychopharmacological and other treatments by persons with psychosis: Self-reported data from the National Study of Low Prevalence (Psychotic) Disorders. Bulletin 4. National Mental Health Strategy. Canberra, Australian Commonwealth Department of Health and Ageing, 2002

Valuri G, Indermaur D, Ferrante A. The Criminal Careers of Drug Offenders in Western Australia: A study of the recidivism and criminal history of those arrested for a drug offence in Western Australia between 1989 and 1999. Report by the Crime Research Centre, University of Western Australia, May 2002.



Almeida OP. Waterreus A. Spry N. Corica T. Martins G. Martins RN. Flicker L. Effect of testosterone deprivation on the cognitive performance of a patient with Alzheimer's disease. International Journal of Geriatric Psychiatry. 2001, 16, 822-825

Morgan V, Jablensky A, Castle DJ . Season of birth in schizophrenia and affective psychoses in Western Australia 1916-1961. Acta Psychiatrica Scandinavica, 2001, 104, 138-147

Jablensky A. Classification of nonschizophrenic psychotic disorders: A historical perspective. Current Psychiatry Reports 2001, 3, 326-331

Gandy S. Almeida OP. Fonte J. Lim D. Waterreus A. Spry N. Flicker L. Martins RN. Chemical andropause and amyloid-beta Journal of the American Medical Association. 2001, 285, 2195-2196

Gureje O, Herrman H, Harvey C, Trauer T, Jablensky A. Defining disability in psychosis: performance of the diagnostic interview for psychosis – disability module (DIP-DIS) in the Australian National Survey of Psychotic Disorders. Australian and New Zealand Journal of Psychiatry 2001, 35, 846-851

Jablensky A, Lawrence D. Schizophrenia and cancer: Is there a need to invoke a protective gene? Archives of General Psychiatry 2001, 58, 579-580. Books and Chapters

Jablensky, A., Johnson, R., Bunney, W., et al. Neurological, Psychiatric, and Developmental Disorders; Meeting the Challenge in the Developing World. Washington DC: National Academy Press, 2001

Jablensky A. Symptoms of schizophrenia. In Henn F., Sartorius N., Helmchen H., Lauter H. (eds) Contemporary Psychiatry, vol 3. Springer, Berlin, 2001, 3-36.

Jablensky A. Schizophrenia. In: Neurological, Psychiatric, and Developmental Disorders. Meeting the Challenge in the Developing World. Institute of Medicine, National Academy of Science, Washington DC, 2001

Mendelson, G., & Jablensky, A. What does psychiatry encompass? In S. Bloch & B. Singh (Eds.), Foundations of Clinical Psychiatry (2nd ed). Melbourne: Melbourne University Press, 2001, 63-81

Reports

Morgan, V., Korten, A., Valuri, G., Waterreus, A. and Jablensky, A on behalf of the Low Prevalence Disorders Study Group. National Survey of Mental Health and Wellbeing. People Living with Psychotic Illness: An Australian Study 1997-98. Confidentialised Unit Record File. Technical paper. September 2001

Valuri G, Morgan V, Jablensky A. Deriving a Research Diagnosis from a Mental Health Register. Report to Western Australian Department of Health. Perth: University of Western Australia Department of Psychiatry and Behavioural Science; 7 March 2001.



Hansen J, de Klerk N, Croft ML, Alessandri P, Burton P. The Western Australian Twin Child Health (WATCH) Study: work in progress. Australasian Epidemiologist 2000, 7, 2

Jablensky A. The concept of schizophrenia: pro et contra. Epidemiologia e Psichiatria Sociale 2000, 8, 242-247

Jablensky A., McGrath J., Herrman H., Castle D., Gureje O., Evans M, Carr V., Morgan V., Korten A., Harvey C. Psychotic disorders in urban areas: an overview of the Study on Low Prevalence Disorders. Australian and New Zealand Journal of Psychiatry 2000, 34, 221-236

Jablensky A. Prevalence and incidence of schizophrenia spectrum disorders: implications for prevention. Australian and New Zealand Journal of Psychiatry 2000, 34, Suppl S26-S34

Jablensky A. Epidemiology of schizophrenia: the global burden of disease and disability. European Archives of Psychiatry and Clinical Neuroscience 2000, 250, 274-85

Lawrence D, Holman CD, Jablensky A, Threlfall TJ, Fuller SA Excess cancer mortality in Western Australian psychiatric patients due to higher case fatality rates. Acta Psychiatrica Scandinavica 2000, 101, 382-388

Lawrence D, Almeida O, Hulse G, Jablensky A Suicide and attempted suicide among older adults in Western Australia. Psychological Medicine 2000, 30, 813-821

Morgan V, Janca A. Revisiting the journal impact factor. Australasian Psychiatry 2000, 8, 230-235 Books and Chapters

Jablensky A Epidemiology of schizophrenia. In Gelder M, Andreassen A, Lopez-Ibor J (eds) New Oxford Textbook of Psychiatry, Vol 1. Oxford University Press, Oxford, 2000, 585-599.

Jablensky A Course and prognosis of schizophrenia. In Gelder M, Andreassen A, Lopez-Ibor J (eds) New Oxford Textbook of Psychiatry, Vol 1. Oxford University Press, Oxford, 2000, 612-621.


Blanchard MR. Waterreus A. Mann AH. Can a brief intervention have a longer-term benefit? The case of the research nurse and depressed older people in the community. International Journal of Geriatric Psychiatry. 1999, 14(9):733-8

Finch C, Valuri G, Ozanne-Smith J. Injury Surveillance During Medical Coverage of Sporting Events – Development and Testing of a Standardised Data Collection Form. Journal of Science and Medicine in Sport 1999, 2, 42-56

Jablensky A. Schizophrenia: epidemiology. Current Opinion in Psychiatry 1999, 12, 19-28

Jablensky A. The conflict of the nosologists: views on schizophrenia and manic depressive illness in the early part of the 20th century. Schizophrenia Research 1999, 39, 95-100

Jablensky A. The Forest and the Trees. Personal History & Health. The Midtown Longitudinal Study 1954-1974, by Leo Srole and Ernest Joel Millman (book review). Contemporary Psychology / APA Review of Books 1999, 45, 221-223

Jablensky A. The nature of psychiatric classification: issues beyond ICD-10 and DSM-IV. Australian and New Zealand Journal of Psychiatry 1999, 33, 137-144

Lawrence D.M., Holman D.J, Jablensky A., Fuller S.A. Suicide rates in psychiatric in-patients: an application of record linkage to mental health research. Australian and New Zealand Journal of Public Health 1999, 23, 468-470

Jablensky A Psychiatric epidemiology and the global public health agenda. International Journal of Mental Health 1999, 28, 6-14 Books and Chapters

Jablensky A. The concept of somatoform disorders: A comment on the mind-body problem in psychiatry. In: Ono Y et al (Eds) Somatoform Disorders: A Worldwide Perspective. Springer, Tokyo, 1999, 3-10

Jablensky A Beyond ICD-10 and DSM-IV: issues in contemporary psychiatry. In Promoting Mental Health Internationally. Ed by de Girolamo G., Eisenberg L. and Goldberg D.P. Gaskell, London, 1999, 47-56

Jablensky A Diagnosing schizophrenia – a personal view. In Maj M. (ed) Evidence and Experience in Psychiatry, vol. 2, World Psychiatric Association, 1999

Jablensky A. The 100-year epidemiology of schizophrenia. In Search for the Causes of Schizophrenia, Vol. IV, ed by W.F. Gattaz and H. Häfner. Steinkopff, Darmstadt, 1999, 3-19


Reports

Croft M. Creation of a Patient Master Index for Tasmania’s Mental Health Services. Commissioned by Tasmania’s Department of Health and Human Services 1999

Jablensky A, McGrath J, Herrman H, Castle D, Gureje O, Morgan V, Korten, A. People Living with Psychotic Illness: An Australian Study 1997-98 - An Overview. National Survey of Mental Health and Wellbeing: Bulletin 1. National Mental Health Strategy. Canberra, Australian Commonwealth Department of Health and Aged Care, 1999.

Jablensky A, McGrath J, Herrman H, Castle D, Gureje O, Morgan V, Korten, A. People Living with Psychotic Illness: An Australian Study 1997-98. National Survey of Mental Health and Wellbeing: Report 4. National Mental Health Strategy. Canberra, Australian Commonwealth Department of Health and Aged Care, 1999.


Finch C, Valuri G, Ozanne-Smith J. Sports and Active Recreation Injuries in Australia - Evidence from Emergency Department Presentations. British Journal of Sports Medicine. 1998, 32, 220-225 Reports

Somerford P, Pinder T, Valuri G, Price S, Stevens M. Bicyle Injury Hospitalisations and Deaths in Western Australia 1981 – 1995. Injury Control Program - Disease Control, Health Department of Western Australia, July 1998

Croft M. Record linkage of the NSW Registrar General’s registrations of deaths to the NSW Inpatient statistics collection records for 1995/96 coronary artery bypass graft patients. Commissioned by NSW Health Department 1998



Jablensky A. The 100-year epidemiology of schizo-phrenia. Schizophrenia Research 1997, 28, 111-125

Jablensky A. Organic origins of psychoses. Brain Pathology 1997, 7, 1043-1046

Jablensky A., Cole S.W. Is the earlier age at onset of schizophrenia in males a confounded finding? British Journal of Psychiatry 1996, 170, 234-240

Morgan V, Castle D, Page A, Fazio S, Gurrin L, Burton P, Montgomery P, Jablensky A. Influenza epidemics and the incidence of schizophrenia, affective disorders and mental retardation in Western Australia: no evidence of a major effect. Schizophrenia Research 1997, 26, 25-39

Stanley F, Read A, Kurinczuk J, Croft M, Bower C. A population maternal and child health research data base for research and policy evaluation in Western Australia. Seminars in neonatology 1997, 2,195-201 Published conference proceedings

Valuri, G. Finch, C., Ozanne-Smith, J. A Standardised Data Collection Methodology for Sports Injury Surveillance. Computerised Data Entry and Analysis System. In: McGuiness B, Leeder T (eds). Making It Happen. Proceedings of the Fourth National Health Informatics Conference. Melbourne, Australia 19th - 21st August 1996, 45- 49 Books and Chapters

Jablensky A. International perspective in transcultural mental health. In: Ferguson B., Barnes D. (eds) Perspectives on Transcultural Mental Health. Transcultural Mental Health Centre, Sydney, 1997, 1-12 Reports

Croft M, Ferrante A. The corporate data warehouse project data matching project. Commissioned by WA Ministry of Justice 1997

Croft M. A description of the availability, accessibility and utility of the major health data bases relevant to research into the incidence, prevalence, management and health outcomes of diabetes in Western Australia . Commissioned by Diabetes Australia (WA) 1997

Croft M. A Proposal to establish a diabetes registry in Western Australia using record linkage. Commissioned by Diabetes Australia (WA) 1997

Day, L., Valuri, J., Ozanne-Smith, J. General Practice Injury Surveillance in the Latrobe Valley. Monash University Accident Research Centre Report No. 113, May 1997

Waterreus A. Mann A. Blanchard M. Aquilina C. Out of the darkness; a training package in the recognition and management of depression in older people for primary health care workers. 1997. Institute of Psychiatry, London, England.


Jablensky A. (1996) Books reconsidered: General Psychopathology by Karl Jaspers. Australian & New Zealand Journal of Psychiatry 1996, 30, 885-888

Morgan V, Castle D, Jablensky A. Seasonality of birth in Western Australia. Letter. British Journal of Psychiatry 1996, 168, 521 Books and Chapters

Jablensky A. (1996) Diagnosis and classification in a developing country. In: Tantam D., Appleby L. and Duncan A. (eds) Psychiatry for the Developing World. Gaskell, London, 1996, 27-47 Reports

Croft M. A feasibility study of the probabilistic record linkage of the NSW Road Traffic Authority’s Road Traffic Accident data base to the NSW Inpatient statistics collection records for 1993/94. Commissioned by NSW Health Department 1996

Finch, C., Valuri G., McGrath, A. Pitching Injury Prevention to Baseballers and Softballers: A Review of the Literature. Monash University Accident Research Centre Report No. 106, Dec 1996



Blanchard, M. R; Waterreus, A; Mann, A. H. The effect of primary care nurse intervention upon older people screened as depressed. International Journal of Geriatric Psychiatry. 1995, 10, 289-298.

Jablensky A. Schizophrenia: recent epidemiological issues. Epidemiologic Reviews 1995, 17, 10-20

Jablensky A. Comments on "Prenatal exposure to influenza epidemics and risk of mental retardation" by Takei N. et al. European Archive of Psychiatry and Clinical Neuroscience 1995, 245, 262-263

Jablensky A. Kraepelin's legacy: paradigm or pitfall for modern psychiatry? European Archive of Psychiatry and Clinical Neuroscienc, 1995, 245, 186-188

Jablensky A. Diagnosis and classification in a developing country. Malaysian Journal of Psychiatry 1995, 3, 1-8 Books and Chapters

Jablensky A. Future perspectives on concepts of disease. In: WHO-CIOMS, The Impact of Scientific Advances on Future Health, World Health Organization, Geneva, 65-73.

Jablensky A. Schizophrenia: the epidemiological horizon. In: Hirsch S.R. and Weinberger D. (eds) Schizophrenia. Blackwell, London , 206-252.

Jablensky A., Eaton W.W. Schizophrenia. In: Jablensky A. [ed] Epidemiological Psychiatry. Bailliere Tindall, London, 283-306.

Reports

Croft M. Report on the linkage of the NSW Neonatal Intensive Care Unit Study data base to the 1992 NSW Midwives’ Data Collection. Commissioned by NSW Health Department 1995

Croft M. Report on the linkage of the NSW Neonatal Emergency Transport Service data base to the 1992 NSW Midwives’ Data Collection. Commissioned by NSW Health Department 1995

Day, L., Valuri, J., Ozanne-Smith, J. General Practice Injury Surveillance in the Latrobe Valley. Draft Report on the First Six Months. Monash University Accident Research Centre Report. Sept 1995.

Valuri, G. Hazard 22 Product Related Injuries - A Selection, Domestic Architectural Glass Injuries, Victorian Injury Surveillance System. 1995, March, 2-5


NERU LOCATION AND CONTACT DETAILS

Neuropsychiatric Epidemiology Research Unit School of Psychiatry & Clinical Neurosciences University of Western Australia M571 Level 3, Medical Research Foundation Building Rear 50 Murray Street Perth, Western Australia 6000 http://www.psychiatry.uwa.edu.au/research/neru Contact details

Professor Vera Morgan PH: +61-(0)8-9224-0235 FAX: +61-(0)8-9224-0285 EMAIL: [email protected]

See Orange Zone No. 5 on the map below.

MRF Building is Orange Zone no. 5


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