name: thomas r. porter, md, facc , fase campus addresscurriculum vitae . name: thomas r. porter, md,...
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CURRICULUM VITAE
NAME: Thomas R. Porter, MD, FACC, FASE CAMPUS ADDRESS: University of Nebraska Medical Center
982265 Nebraska Medical Center Omaha, NE 68198-2265 (402) 559-7977
Birth Date: August 25, 1958 Fremont, Nebraska
Wife: Lee A. Porter Children: Austin, Evan, Kaitlin, Dawson, and Megan Home Address: 16445 Leavenworth Circle
Omaha, Nebraska 68118 EDUCATION: University of Nebraska-Lincoln
Lincoln, Nebraska Bachelor of Science September 1976 University of Nebraska Medical Center Omaha, Nebraska Doctorate of Medicine September 1980 – May 1984
POST-DEGREE TRAINING: Medical College of Virginia Richmond, VA Internal Medicine Residency Training July 1984 – June 1987 Medical College of Virginia Richmond, VA Chief Resident, Department of Internal Medicine July 1987 – June 1988 Medical College of Virginia Richmond, VA Cardiology Fellow July 1988 – June 1991 Duke Medical Center Durham, North Carolina Cardiovascular Magnetic Resonance Fellowship July 2006 – June 2007
MD Imaging Fort Lauderdale, Florida Cardiovascular Computed Tomography Level I, II, III July 2007 – June 2009
ACADEMIC APPOINTMENTS: Courtesy Professor of Cellular& Integrative Physiology 07/14-Present Department of Cellular& Integrative Physiology University of Nebraska Medical Center Omaha, Nebraska Courtesy Professor of Pediatric Cardiology 07/09- Present Department of Pediatrics University of Nebraska Medical Center Omaha, Nebraska Courtesy Professor of Radiology 3/09- Present Department of Radiology University of Nebraska Medical Center Omaha, Nebraska
Director, Non-invasive Cardiology Laboratory 7/02 - Present Professor of Medicine Theodore F. Hubbard Distinguished Chair of Cardiology Department of Internal Medicine/Cardiology University of Nebraska Medical Center Omaha, Nebraska Director, Non-invasive Cardiology Laboratory 3/96 – 7/02 Associate Professor of Medicine University of Nebraska Medical Center Omaha, Nebraska Director, Non-invasive Cardiology Laboratory 6/92-3/96 Assistant Professor of Medicine University of Nebraska Medical Center Omaha, Nebraska
Co-Director, Non-invasive Cardiology Laboratory 7/91-6/92 Assistant Professor of Medicine McGuire Veterans Administration Medical Center Richmond, Virginia CERTIFICATIONS: American Board of Internal Medicine (9/87) American Board of Internal Medicine for Subspecialty of Cardiovascular Disease (11/91) American Board of Internal Medicine for Subspecialty of Cardiovascular Disease (2001-2011) American Board of Internal Medicine for Subspecialty of Cardiovascular Disease (2012-2022) National Boards of Echocardiography June (2006-2016) #2006-041 Cardiovascular Computed Tomography Board Certification (2009-2019)
STATE MEDICAL LICENSE: Nebraska No. 18875 GRANT/CONTRACT SUPPORT: 02/12 – 1/17 Therapeutic Use of Ultrasound in Acute and Chronic Coronary Artery Disease. Brazilian FAPESP Amount: $600,000 (Co-PI: Porter) 02/13 – 01/15 Development of Theranostic Ultrasound (PI Porter) NIH 1 R21 EB015163-01A1 Amount: $275,000 07/12 – 09/15 Regadenoson Real Time Perfusion Imaging Trial – Optison (PI: Porter) Astellas Pharma Global Development, Inc / GE Healthcare 09/11 – 02/15 Utilization of Magnetic Resonance Imaging to Evaluate Ultrasound and Microbubble-Guided Therapies Targeted to the Cerebral and Coronary Circulation Project (PI: Porter) Philips Medical Systems MR, Inc 08/10 -06/15 Bioengineering Research Partnership for Therapy for Acute Myocardial Infarction (PI: Porter) Oregon Health and Sciences University / NIH R01HL095868 09/08-08/13 Sonolysis in Acute Coronary Syndromes. (PI: Feng Xie) NIH: 1 RO1 EB009050-01 Porter (Co-PI) Amount: $2,812,383
03/09 – 08/10 Regadenoson Real Time Perfusion Imaging Trial (PI: Porter, TR) Astellas Pharma, Inc Amount: $198,303.00 08/08-08/11 Detection of Significant Coronary Artery Disease in High Risk Nephropathy Patients Utilizing Coronary Computed Tomographic Angiography (CTA) and Real Time Perfusion Dobutamine Stress Echocardiography (DSE with RTCE): Comparison with Quantitative Coronary Angiography (QCA) and Patient Outcome University of Nebraska Medical Center Clinical Research Center Amount: $28,669.60
09/07 – 08/09 Targeted Blood Brain Barrier Permeability Changes with Ultrasound and Microbubbles NIH STTR grant 1R41NS057860-01; applicant organization: ImaRx Therapeutics, Inc. Amount: $ 603,038 (direct costs: 410,230) 09/07 – 09/10 Definity Real Time Perfusion During Dobutamine Stress Echo Database Bristol Myers Squibb Direct Cost: $174,603
11/06-7/07 A Multicenter, Phase IV, Study to Evaluate the Ability of Definity-Enhanced versus Unenhanced Echocardiography to Improve the Accuracy and Reproducability of Left Ventricular Ejection Fraction when Compared to Cardiac Magnetic Resonance Imaging Bristol Myers Squibb Direct Costs: $ 59,745 10/05 – 08/07 Sonothrombolysis of Vascular Clots with Targeted Bubbles NIH SBIR Grant 2 R44 HL071433-02; ImaRx Therapeutics Inc. Amount: $253,183 (direct costs: $172,234) 10/05 – 12/05 A Single-Center, Phase IV, Retrospective Study to Assess the Electrocardiographic Safety of Definity in Combination with Dipyridamole Stress and High-MI End-Systolic Triggering Bristol Myers Squibb Medical Imaging Amount: $40,934 (direct costs: $30,900) 8/04-9/05 Blinded reader on Phase 3 AI-700 rest/stress imaging Studies for Acusphere. Amount: $28,000. 5/04 – 4/07 Microbubble Potentiated Ultrasound as a New Method of Declotting Thrombosed Dialysis Grafts ImaRx Therapeutics Inc.; PI: Thomas R. Porter, MD Total: $506,500 5/04 - 4/05 A Chronic Study of Non-invasive Recanalization of Intracoronary Thrombi with Ultrasound and Intravenous Microbubbles ImaRx Therapeutics Inc.; PI: Thomas R. Porter, MD Total: $199,495 6/04 - 5/05 A Phase 1b, Randomized, Single Blind Study Evaluating Resten-MP (AVI-4126 Bound to
Perfluorcoarbon Exposed Sonicated Dextrose Albumin) in Subjects with Focal De Novo Stenosis. AVI BioPharma Inc.; PI: Thomas R. Porter, MD Total $541,946 4/04 – 3/05 An Open Label, Non-Randomized, Phase IV Trial to Compare Definity-Enhanced Rest and Dipyridamole Stress Echocardiography to Nuclear Perfusion Imaging for the Detection and Localization of Perfusion Abnormalities Bristol-Myers Squibb Medical Imaging; PI: Thomas R. Porter, MD Amount: $131,544 1/04 - 6/05 Detection of Coronary Artery Disease with a Continuous Infusion of Definity Ultrasound Contrast During Adenosine Stress Echocardiography” Astellas Pharma US, Inc. (formerly Fujisawa Healthcare Inc.); PI: Thomas R. Porter, MD Amount: $127,036 10/03 - 3/04 Alterations in Blood Brain Barrier Permeability Following Intravenous Injections of Microbubbles During Transcranial Ultrasound The Sanfilippo Syndrome Medical Research Foundation; PI: Thomas R Porter, MD Total $19,840 2/03 - 2/04 Treatment of Thrombosed Anteriovenous Shunts with Intravenous PCMB and Low Frequency Ultrasound in a Canine Model ImaRx Therapeutics, Inc.; PI: Thomas R. Porter, MD Total: $64,704 7/03 - 12/03 An Open-Label, Non-Randomized, Phase IV, Follow-up Trial to Compare Infusion Dosing Against Bolus Dosing for Use in Definity-Enhanced Rest and Dipyridamole Stress Echocardiography for the Detection and Localization of Perfusion Abnormalities Bristol-Myers Squibb Medical Imaging 115-908; PI: Thomas R.Porter,MD Total: $22,500 5/03 - 10/03 An Open-Label, Randomized, Phase IV Trial to Determine the Accuracy of Definity-enhanced Echocardiography During Dipyridamole Stress to Localize Perfusion Abnormalities in Subjects with Suspected or Known Coronary Artery Disease Bristol-Myers Squibb Medical Imaging; PI: Thomas R. Porter, MD Total: $163,296
4/03 - 9/03 Non-invasive Recanalization of Intracoronary Thrombi with Intravenous Microbubbles ImaRx Therapeutics, Inc.; PI: Thomas R. Porter, MD Total: $81,300 8/02 - 7/03 Inhibition of Intracoronary Stent-induced Intimal Hyperplasia with Targeted Microbubbles Carrying the E2F Decoy Oligonucleotide University of Nebraska Medical Center-Gene Therapy Program Total: $15,000 7/02 - 6/03 Prevention of Ischemic Left Ventricular Dysfunction with Intravenous Perfluorocarbon Containing Microbubbles”, Max Baer Fraternal Order of Eagles; PI: Thomas R. Porter, MD; Total: $5,000 The CADET Trial: Contrast Assisted Dobutamine Echo Trial: Detection of Coronary Stenoses with Intravenous Dobutamine Stress Contrast Echocardiography: Incremental Benefit of Myocardial Perfusion Over Wall Motion Analysis. Amersham Health Inc.; PI: Thomas R. Porter, MD Total: $307,725 (multi-center grant) 6/02-5/03 The CADET Trial: Contrast Assisted Dobutamine Echo Trial: Detection of Coronary Stenoses with Intravenous Dobutamine Stress Contrast Echocardiography: Incremental Benefit of Myocardial Perfusion Over Wall Motion Analysis. Amersham Health Inc.; PI: Thomas R. Porter, MD; Total: $93,667 (clinical grant) 10/00 - 8/02 Therapeutic Applications of Microbubbles - Phase II, NIH STTR Phase II (Small Business Technology Transfer Program), PI: Thomas R. Porter, MD, Applicant Organization: AVI Biopharma, Corvallis, OR, 9/30/00 - 8/31/02 Total: $753,891 9/99 - 9/01 RV-Can vs RV-SVC-Can: A Multicenter, within Patient, Comparison of Defibrillation Efficacy Between a Two-electrode System (RV-Can) and a Three-electrode System (RV-SVC-Can) – Is Heart Size the Determining Factor?, St Jude Medical Cardiac Rhythm Management Division. Direct costs: $12,000. PI: Thomas R. Porter, MD 7/1/99-6/30/01 Determining the Optimal Ultrasound Parameters for Microbubble-Mediated Gene Uptake in Human Coronary Arteries. American Heart Association, Nebraska Grant-in-Aid; Direct costs: $34,911. Principal Investigator: Thomas R. Porter, MD
7/99 - 6/01 Determining the Optimal Ultrasound Parameters for Microbubble-mediated Gene Uptake in Human Coronary Arteries, American Heart Association Nebraska Grant-in-Aid, Direct costs: $69,911, PI: Thomas R. Porter, MD 8/99-8/00 An Open-Label, Non-randomized, Phase II, Single Center Trial to Evaluate the Ability of DMP 115-Enhanced Echocardiographic Evaluation of Wall Motion and Perfusion Abnormalities (at Rest and During Treadmill Exercise Stress) Using Accelerated Intermittent Harmonic Imaging Acquisition Techniques to Detect Coronary Artery Disease in Subjects with Suspected Disease. DuPont Pharmaceuticals Company. Direct costs: $137,767.20 Principal Investigator: Thomas R. Porter, MD 7/1/99-6/30/00 Prevention of Myocardial Ischemia Using Intravenous Perfluorocarbon Exposed Sonicated Dextrose Albumin Microbubbles Sonicated in a Nitrogen-free Environment. Max Baer Heart Fund; Direct costs: $5,000. Principal Investigator: Thomas R. Porter, MD 2/98 - 2/00 Right Ventricular Outflow Versus Apical Pacing in Pacemaker Patients with Congestive Heart Failure and Atrial Fibrilation (ROVA Trial). St. Jude Medical, Rhythm Management Division; Echocardiography Core Laboratory PI: Thomas Porter, MD Amount $30,000 7/1/97-6/30/99 The Mechanism for Improved Ultrasound Contrast with Intermittent Imaging. American Heart Association; Direct costs: $38,992. PI: Thomas R. Porter, MD 7/1/98-6/30/99 Therapeutic Application of Perfluorocarbon Microbubbles. NIH STTR Phase I (Small Business Technology Transfer Program); Direct costs: $49,955. PI: Patrick L. Iversen, Ph.D.; Co-PI: Thomas R. Porter, MD. 7/1/98 - 6/30/99 In Vivo Recanalization of Acute Coronary Artery Thrombosis with Intravenous Perfluorocarbon Exposed Sonicated Dextrose Albumin Microbubbles.UNMC Seed Research Grant; Direct costs: $14,976. PI: Thomas R. Porter, MD 9/98 - 8/99 Validation of Accelerated Intermittent Harmonic Ultrasound Imaging with Intravenous Ultrasound Contrast to Assess Perfusion During Exercise and Dobutamine Stress Echocardiography. Clinical Research Center grant; Direct costs: $11,720. PI: Thomas R. Porter, MD
11/98 - 10/99 An Open-Label Phase 2 Study to Compare Optison Myocardial Contrast Echocardiography (MCE) to Single Photon Emission Computed Tomography (SPECT) for the Detection of Ischemia in Patients Undergoing Exercise Stress. Molecular Biosystems Inc. Amount $186,111 PI: Thomas R. Porter, MD 2/99-6/99 Antilog Corrected Color Coded Digital Subtraction Contrast Echocardiography During Intermittent Harmonic Ultrasound Imaging with Intravenous Ultrasound Contrast to Assess Perfusion During Exercise and Dobutamine Stress Echocardiography. Advanced Technology Laboratories, Inc. Amount $14,000 PI: Thomas R. Porter, MD 9/1/97-8/31/98 Incremental Benefit of Intermittent Harmonic Ultrasound Imaging in Acute Myocardial Infarction. Cardiology Section Grant; Direct costs: $20,000. PI: Thomas R. Porter, MD 7/1/97-6/30/98 Prevention of Carotid Artery Stenosis Following Balloon Injury with Intravenous 15-mer Antisense Oligonucleotide Bound to Perfluorocarbon Exposed Sonicated Dextrose Albumin Microbubbles and Transcutaneous Continuous Wave Diagnostic Ultrasound. UNMC Collaborative Seed Grant; Direct costs: $14,921. Co-PIs: Patrick L. Iversen and Thomas R. Porter, MD. 10/97-12/31/98 International Working Group for Perfusion Imaging with Intermittent Harmonic Ultrasound Standardization of Protocols using HDI Lab. Advanced Technology Laboratory; Direct costs: $200,085. PI: Thomas R. Porter, MD (funded: 1998 - $50,000) 7/1/95-6/30/97 Intravenous Ultrasound Contrast Quantifies Myocardial Function and Flow after Reperfusion. American Heart Association, Nebraska Affiliate Grant-in-Aid; Direct costs: $39,636. PI: Thomas R. Porter, MD. 7/1/96-6/30/97 External Ultrasound-Mediated Delivery of Intravenous c-myc Antisense Oligomer-Labeled Perfluorocarbon-Exposed Sonicated Dextrose Albumin Microbubbles to Reduce Neointimal Formation in a Porcine Model of Coronary Artery Injury. UNMC Seed Grant; Direct costs: $10,000. PI: Thomas Porter, MD. 7/1/96-6/30/97 The Clinical Utility of Intravenous Perfluorocarbon-Exposed Sonicated Dextrose Albumin Microbubble Contrast during Stress Echocardiography. Max Baer Heart Fund, Fraternal Order of Eagles; Direct costs: $5,000. PI: Thomas R. Porter, MD.
4/94 - 1996 Hospital Seed Grant, $95,257. 7/94 - 6/95 Altering Microbubble Gas Solubility Directly Influences Left Ventricular Video Intensity Following IV Injection. American Heart Association (Nebraska) Grant-in-Aid Award; Direct costs: $19,950. PI: Thomas R. Porter MD 7/94 - 6/95 Altering Microbubble Gas Solubility Directly Influences Left Ventricular Video Intensity Following IV Injection. American Heart Association (Nebraska) Grant-in-Aid Award; Direct costs: $19,950. PI: Thomas R. Porter MD 6/94 - 8/94 American Heart Association, $1,500. 7/93 - 6/94 UNMC Seed Grant, $7,500. PATENTS: 1. A Method and Composition for Optimizing Left Ventricular Videointensity in Echocardiography.
(#5,578,291)(UNMC Docket #63044) November 26, 1996. 2. A New Ultrasound Contrast Agent and Methods for Their Manufacture and Use. (#5,567,415)(UNMC
Docket #63702) October 22, 1996. 3. Perfluorobutane Ultrasound Contrast Agent and Methods for Its Manufacture and Use.
(#5,701,899)(UNMC Docket #63702.2) December 30, 1997. 4. Suspended Ultrasound Microbubble Cavitation Imaging. (#5,560,364)(UNMC Docket #63089) October
1, 1996. 5. Suspended Ultrasound Induced Microbubble Cavitation Imaging. (#5,560,369)(UNMC Docket #63089.1)
November 11, 1997. 6. Thrombolytic Agents and Methods of Treatment for Thrombosis. (#5,648,098)(UNMC Docket #63095)
July 15, 1997. 7. Targeted Site Specific Drug Delivery Composition and Methods of Use (#6,245,747 B1)(UNMC Docket
#63107.1) June 12, 2001. 8. Targeted Site Specific Drug Delivery Compositions and Methods of Use (European Patent No. 0 888 054
B1). September 3, 2003. 9. Perfluorocarbon Ultrasound Contrast Agent Comprising Microbubbles Containing a Filmogenic Protein
and a Saccharide. (#5,695,740) December 9, 1997. 10. Compositions and Methods for Altering the Biodistribution of Biological Agents (#5,849,727)(UNMC
Docket #63107A) December 15, 1998. 11. Methods for Inducing Atrial and Ventricular Rhythms Using Ultrasound and Microbubbles
(#6,439,236B1) (UNMC Docket #63138.PCT) August 27, 2002 12. Thrombolytic Agents and Methods of Treatment for Thrombosis (#6,197,345) (UNMC Docket No.
63095.2) March 6, 2001. 13. Suspended Ultra-Sound Induced Microbubble Cavitation Imaging. (#6,080,386) June 27, 2000. 14. Composition and Methods for Altering the Biodistribution of Biological Agents. (#6,117,828) (UNMC
Docket No. 63107) September 12, 2000. 15. Thrombolytic Agents and Methods of Treatment for Thrombosis. (#6,197,345) March 6, 2001.
16. Hemodynamic Effects of Intravenous PESDA Microbubbles During Acute Myocardial Ischemia (Pending) (UNMC Docket #63158.P).
17. Microbubble Compositions and Methods for Oligonucleotide Delivery (US-2004-0013662-A1, Publication Number) (UNMC Docket #63107A3).
18. Thrombolytic Agents and Methods of Treatment for Thrombosis (UNMC Docket No.63095.3)Thrombolytic Agents and Methods of Treatment for Thrombosis
19. Compositions and Methods for Altering the Biodistribution of Biological Agents (#6,537,814) March 25, 2003.
20. Suspended Ultra-sound Induced Microbubble Cavitation Imaging (#6,080,386) June 27, 2000. CONSULTING POSITIONS: UNMC cardiology MILITARY SERVICE: None HONORS AND AWARDS: Merck Award for Chemistry - University of Nebraska 1980 Chancellor's Scholar - University of Nebraska 1980 American College of Cardiology/Bristol Travel Award 1991 Finalist for the 1991 Samuel A. Levine Young Investigator Award 1992 American College of Cardiology Young Investigator Award American Society of Echocardiography Young Investigator Award 1994 One of Top Ten Teachers in Internal Medicine 1997 One of Top Ten Teachers in Internal Medicine 1998 One of Top Ten Teachers in Internal Medicine 1999 One of Top Ten Teachers in Internal Medicine 2000 Selected to present First Annual Feigenbaum Lecture, 2000 Scientific Sessions of the American Society of Echocardiography, June 11-14, 2000, Chicago, IL Certificate of Appreciation for Excellence in Teaching, presented by Alvin M. Earle Outstanding Health Science Award Committee, November 28, 2000 Internal Medicine Clinical Research Award 2001 Top Teacher Award in Internal Medicine 2001 Top Teacher Award in Internal Medicine 2002 Joseph P. Gilmore Outstanding Investigator, 2002 Certificate Recognizing Outstanding Professional Achievement, College of Medicine 2002 Selected among the Best Doctors for 2003, Best Doctors, Inc., Boston, Mass. Top Teacher Award in Internal Medicine 2003 Theodore F. Hubbard Chairman of Cardiology, University of Nebraska Medical Center 2004 Top Teacher Award in Internal Medicine 2004 Top Teacher Award in Internal Medicine 2005 Best Doctor in America 2005-2006, Cardiovascular Diseases Top Teacher Award in Internal Medicine 2006 Top Teacher Award in Internal Medicine 2007 Top Teacher Award in Internal Medicine 2008 Distinguished Scientist Award, UNMC 2008 Top Teacher Award in Internal Medicine 2009 Distinguished Alumni, VCU 2011 Top Teacher Award in Internal Medicine 2012 University of Nebraska Outstanding Research and Creative Activity Award 2013 Top Teacher Award in Internal Medicine 2013 Exceptional Achievement Award, College of Medicine 2013 Career Investigator Award, Department of Internal Medicine 2014
HONORARY FRATERNITIES: Alpha Omega Alpha Honorary Fraternity Phi Beta Kappa Honorary Fraternity MEMBERSHIPS AND OFFICES IN PROFESSIONAL SOCIETIES: American College of Cardiology Fellow of American College of Cardiology American Heart Association Clinical Cardiology American Society of Echocardiography Fellow of American Society of Echocardiography Society of Cardiovascular Computed Tomography Society of Cardiovascular Magnetic Resonance
COMMITTEE ASSIGNMENTS: NIH Grant Review Committee DSR 2015 A. Ross McIntyre Award Committee 2014-2015 Department of Internal Medicine Research Committee – 1994 - present ASE Board of Directors 2000-2003 Institutional Animal Care and Use Committee - 2001 - 2004 ASE Public Relations Committee 2004-2005 ASE Writing Group 2004 - present ASE Best Practices Writing Group 2004-2005 ACC Imaging Chair 2008-2009 JACC Editorial Board 2007 – present JASE Editorial Board 2007- present ASE EchoSAP – 2009 ASE Extra Mural Research Committee 2008 – present ASE Guidelines and Standards Committee 2009-present NIH Grant Review Committee BMIT – 2012 NIH Grant Review Committee NHLBI SMARTT Program- 2012 Chair, ASE Research Committee 2014 British Society of Echocardiography Journal Editorial Board 2014 PROFESSIONAL SOCIETY MEMBERSHIPS/COMMITTEES: American College of Cardiology
Committees: Editorial Board July 1998 - June 2002 Emergency Cardiac Care Committee 1997 - 2000 Echocardiography Committee 1998 - 2004 1998 Annual Scientific Session Program Committee (abstract grader) 1999 Annual Scientific Session Program Committee (abstract grader) 2000 ACC Special Opinion Panel 2000 Annual Scientific Session Program Committee (abstract grader)
2001 Annual Scientific Session Program Committee (abstract grader) 2002 Annual Scientific Session Program Committee (abstract grader) 2003 Annual Scientific Session Program Committee (abstract grader) 2004 Annual Scientific Session Program Committee (abstract grader)
2005 American College of Cardiology Committee (abstract grader) 2006 American College of Cardiology Committee (abstract grader)
2007 American College of Cardiology Committee (abstract grader) 2008 American College of Cardiology Committee (abstract grader) 2009 American College of Cardiology Committee Chair 2009 American College of Cardiology Committee (abstract grader) 2010 American College of Cardiology Committee (abstract grader) 2011 American College of Cardiology Committee (abstract grader) 2011 ACC SAP7 Writing Group 2012 American College of Cardiology Committee (abstract grader) 2013 American College of Cardiology Committee (abstract grader) 2014 American College of Cardiology Committee (abstract grader)
AMERICAN SOCIETY FOF ECHOCARDIOGRAPHY COMMITTEES:
Physics and Instrumentation Committee 1997 - 1999 Development Committee 1997 - 2000 Public Relations Committee 1999 - 2003 ASE Task Force/Writing Group on Standards and Guidelines for the Use of Ultrasound Contrast in Echocardiography ASE Task Force to Develop a Standardized Echocardiography Reporting Form 1997 ASE Program Committee (abstract grader for the Eighth Annual Scientific Sessions) 1998 ASE Program Committee (abstract grader for the Ninth Annual Scientific Sessions) 1998-2002 Member, Board of Directors, American Society of Echocardiography the Guidelines and Standards Committee 1999 ASE Program Committee (abstract grader for the Tenth Annual Scientific Sessions) 2000 ASE Program Committee (abstract grader for the Eleventh Annual Scientific Sessions)
2001 ASE Program Committee (abstract grader for the Twelfth Annual Scientific Sessions) 2002 ASE Program Committee (abstract grader for the Thirteenth Annual
Scientific Sessions) 2003ASE Program Committee (abstract grader for the Fourteenth Annual 2000-2003 Member, Board of Directors, American Society of Echocardiography
ASEeXAM Review Course Committee 2001-2004 Member Editorial Board, American Society of Echocardiography
2004 ASE Program Committee (abstract grader for the Fifteenth Annual Scientific Sessions) 2004-2006 Member Contrast Writing Group, American Society of Echocardiography 2005 PR Committee for ASE 2005 ASE abstract grader 2005-2006 Member Best Practices Writing Group, American Society of Echocardiography 2007 ASE abstract grader 2008 Member Contrast Writing Group, American Society of Echocardiography 2008 ASE abstract grader 2008 ASE Concerto Faculty 2008 ASE Extra Mural Research Group 2009 Member Contrast Writing Group, American Society of Echocardiography 2009 ASE abstract grader 2009 ASE Advanced EchoSAP 6
2009 ASE Concerto Faculty 2009 ASE Extra Mural Research Group 2010 Member Contrast Writing Group, American Society of Echocardiography 2010 ASE abstract grader 2010 ASE Extra Mural Research Group 2011 ASE Writing Group 2011 ASE Abstract Grader Scientific Sessions 2012 ASE Concerto Faculty 2012 ASE Abstract Grader Scientific Sessions 2012 ASE Extra Mural Research Group 2012 ASE Writing Group 2013 ASE Writing Group 2014 ASE Research Committee Chair 2015 ASE Guideline Chair AMERICAN HEART ASSOCIATION COMMITTEES:
2000 Scientific Session Program Committee (abstract grader for 73rd Scientific Session) 2001 Scientific Session Program Committee (abstract grader for 74th Scientific Session) 2002 Scientific Session Program Committee (abstract grader for 75th Scientific Session) 2003 Scientific Session Program Committee (abstract grader for 76th Scientific Session) 2004 Scientific Session Program Committee (abstract grader for 77th Scientific Session) 2005 Scientific Session Program Committee (abstract grader for 78th Scientific Session) 2006 Scientific Session Program Committee (abstract grader for 79th Scientific Session) 2007 Scientific Session Program Committee (abstract grader for 80th Scientific Session) 2008 Scientific Session Program Committee (abstract grader for 81th Scientific Session) 2009 Scientific Session Program Committee (abstract grader for 82th Scientific Session) 2010 Scientific Session Program Committee (abstract grader for 83rd Scientific Session) 2011 Scientific Session Program Committee (abstract grader for 84th Scientific Sessions) 2012 Scientific Session Program Committee (abstract grader for 85th Scientific Sessions) 2013 Scientific Session Program Committee (abstract grader for 86th Scientific Sessions) 2014 Scientific Session Program Committee (abstract grader for 87th Scientific Sessions)
SESSIONS CHAIRMAN: 1995: American Society of Echocardiography, "Methods of Analysis", Toronto, Canada, June 14-16 American College of Cardiology, Annual Scientific Session,” Advances in Contrast Echocardiography: Transvenous Applications”, New Orleans, LA, March 19-22 (Co-chairman) 1998: American College of Cardiology, Annual Scientific Session “New Echocardiographic Advances for Understanding and Therapy of Coronary Artery Disease”, Atlanta, GA, March 28-April 1, 1998 (Co-chair) III World Congress (Chair)
1999: American College of Cardiology, 13th Annual Echocardiographic Symposium on 2-D and Doppler Echocardiography, Vail, CO, Aug 1-5,1999 (Co-Director) 2000-2001: American College of Cardiology, Learning Center: “Echocardiography in Coronary Artery Disease and Heart Failure: Case Studies and Practical Applications” Bethesda, MD, June 11-13, 2001 (Co-Director) 2004: American Society of Echocardiography 15th Annual Scientific Sessions “Contrast Echo: Current and Future Clinical Applications” June 26-30, 2004. San Diego, CA 2005: College of Medicine – certificate recognizing “Special Professional Achievement”, March 31, 2005 American College of Cardiology Scientific Sessions, Orlando FL. Invited speaker. Session Type: Mini Course. Session Title: Bad Ventricle, Bad Coronaries: Now What? Presentation Title: Dobutamine Echo Imaging. 2008: American Heart Association Conference Chair American College Cardiology Conference Chair American Society of Echocardiography Conference Co-Chair 2009: American Heart Association Conference Chair American College Cardiology Conference Chair American Society of Echocardiography Conference Co-Chair Rotterdam, Netherlands 14th Annual Contrast Echocardiography symposium Conference Faulty 2010: American College Cardiology Conference Chair and Faculty American Society of Echocardiography Conference Co-Chair Rotterdam, Netherlands 15th Annual Contrast Echocardiography symposium Conference Faculty Feinstein Bubble Conference Faculty American Heart Association Scientific Session Co-Chair 2011: Rotterdam, Netherlands 16th Annual Contrast Echocardiography symposium Conference Faculty American College of Cardiology Conference Chair and Faculty American Society of Echocardiography Scientific Sessions Co-Chair Feinstein Bubble Conference –Faculty American Heart Association Scientific Sessions Chair
2012 Rotterdam, Netherlands 17th Annual Contrast Echocardiography Symposium Conference Faculty American Society of Echocardiography Echo Hawaii Session Chair and Invited Lecturer American College of Cardiology Conference Co-Chair and Faculty American Society of Echocardiography Scientific Sessions Chair and Invited Lecturer American Heart Association Scientific Sessions Chair and Faculty 2013 Rotterdam, Netherlands 18th Annual Contrast Echocardiography Symposium Conference Faculty American Society of Echocardiography Echo Minneapolis Session Chair and Invited Lecturer American College of Cardiology Conference Co-Chair and Faculty 2014 American Society of Echocardiography Echo Hawaii Session Chair and Invited Lecturer American College of Cardiology Conference Co-Chair and Faculty 2015 Rotterdam, Netherlands 20th Annual Contrast Echocardiography Symposium Conference Faculty American Society of Echocardiography Scientific Sessions Invited Lecturer- June 2015 American College of Cardiology Conference Co-Chair and Faculty PRESENTATIONS: INVITED SPEAKER/ LECTURES/ FACULTY PRESENTER 03/2015 ASE Live Webinar 01/2015 20th Annual Contrast Echo Symposium UNMC Advances in Cardiovascular Medicine 12/2014 Northeast GA Medical Center, Grand Rounds, Dec 5, 2014 11/2014 AHA Scientific Sessions, Chicago, Illinois 10/2014 Acoustical Society of America, invited lecturer: Special session on Cavitation Control and Detection Techniques
10/2014 Bubble Conference: 29th Annual Advances in Contrast Ultrasound 10/2014 IBISCIS Cardiology Conference, Sao Paulo, Brazil – Oct 2014 09/2014 ASE Live Webinar 07/2014 Chairman, ASE Research Committee Service for 2014 and Co-Chair of the
Guidelines and Standards Committee. 04/2014 AIUM Annual conference Las Vegas, NV
Development of Ultrasound Theranostic Protocols for Clinical Applications 03/2014 ACC 2014 Scientific Sessions Washington DC Targeted Microbubble Therapy: A Look Into the Future 01/2014 24th Annual Echo Hawaii
Clinical Application of Echo Diastolic Measurements – Proper use of Data. Reading with the experts: Complex Case Studies of LV Function and Hemodynamics. A. DeMaria and T. Porter
Case Studies in Contrast: LVO T/ Belick, P. Grayburn, H. Leong-Poi and T. Porter Contract for Myocardial Perfusion: How and Why? T. Porter
Practical Workshop: Optimizing Contrast on your Echo System. T. Belick, H. Leong-Poi, M. McCulloch, and T. Porter
12/2013 Grand Rounds University of Cincinnati December 16, 2013 Development of Ultrasound Theranostic Protocols for Clinical Applications
11/2013 AHA 2013 Scientific Sessions Appropriate Indications/Use of Stress Echocardiography 2013: The Essentials 10/2013 Bubble Conference
Basis for Ultrasound Parameters used for Initial Clinical Trials in Ultrasound Thrombolysis
06/2013 ASE scientific Sessions 2013 04/2013 AIUM 2013 April 6-10 New York, NY Microbubbles and Drug/Gene Delivery 03/2013 ACC 2013 Scientific Sessions 01/2013 18th European Symposium on Ultrasound Contrast Imaging January 2013, Rotterdam, The Netherlands
• The Future of Sonothrobolysis 11/2012 AHA 2012 Scientific Sessions
• Prospective evaluation of outcomes with stress perfusion imaging versus stress wall motion imaging during dobutamine or exercise echocardiograph
• Myocardial Contrast Echocardiography • Contrast and stress echocardiography: advancing clinical application
09/2012 27th Annual Advances in Contrast Ultrasound Bubble Conference • Perfusion Clinical Trials • Stroke Therapy Update
07/2012 ASE 2012 Scientific Sessions • Therapeutic Ultrasound • Myocardial Perfusion: What does it provide incremental information?
06/2012 ISTU Conference – Germany 05/2012 Grand Rounds – Little Rock, AK 04/2012 Grand Rounds – Norfolk, VA 03/2012 XVII World Congress of Echocardiography and Allied Technique – Sao
Paulo, Brazil 01/2012 European Contrast Symposium 2012 01/2012 ASE Echo Hawaii 2012
• ASE/EAE Guidelines: What Are They and How Do They Work in the Practice?
• Case Studies in Contrast: LVO • Incremental Value of Contrast for Improved Endocardial Definition • Endocarditis: How to Treat and When to Operate • Assessing the Patient Following Congenital Repair • Case Studies in Contrast • CONCERTO 2012 Contrast Program: Practical Workshop: Optimizing
Contrast on Your Lab’s System 10/2011 Virginia Commonwealth Grand Rounds 10/2011 University of Arizona Grand Rounds 09/2011 Feinstein Bubble Conference
• Perfusion Clinical Trial • Stroke Therapy Update
06/2011 Netherlands Symposium Keynote Speaker 06/2011 ASE 2011 Scientific Sessions
• Therapy and targeted imaging with contrast • Can Perfusion Help?
04/2011 ACC 2011 Scientific Sessions
• Integrated Imaging Spotlight: Multi-Modality Development in Myocardial Perfusion Imaging
• Stress Echocardiography: Current and Emerging Applications 01/2011 2011 Rotterdam Symposium 11/2010 AHA 2010 Scientific Sessions
• Cardiovascular Ultrasound Technology Summit • Effects of Underlying Coronary Atherosclerosis on the effectiveness of three
dimensional guided high mechanical index impulses and intravenous microubbles in treating acute coronary thromboses.
9/2010 25th Annual Bubble Conference 6/2010 SOPE Presentation – Ultrasound Directed Gene and Drug Delivery San Diego 6/2010 ASE 2010 Scientific Sessions
• Contrast Perfusion Imaging in Decision-Making: Perfusion During Stress Imaging- Adding Value to Wall Motion
• Echo in Cutting Edge Medicine: Therapeutic Ultrasound: The power of Sound
3/2010 ACC 2010 Scientific Sessions • Integrated Imaging Spotlight: Advances in Cardiac Imaging Technology
- Advances in Echocardiography: Myocardial Perfusion: From Bench to Bedside
• i2 Symposium Update on Echocardiography and Nuclear Cardiology for the Interventionalist: Echo Perfusion Imaging for CAD (A Primer)
2/2010 Snowmass 2010 Advances in Echocardiography • Interesting Mulit-Modality Imaging Cases and Their Outcomes • Clinical Applications of Perfusion Imaging with Ultrasound Contrast
Agents • Use of Ultrasound Contrast during Stress Echo • Targeted Drug Delivery with Ultrasound contrast Agents • Echo in Acute Non-Coronary Syndromes
1/2010 15th European Symposium on Ultrasound Contrast Imaging, Rotterdam,
Netherlands – Faculty Presenter 11/2009 2009 AHA Scientific Session
• Functional Imaging of Coronary Artery Disease - Echocardiographic Measurement of Coronary Perfusion and Function
• Ask the Experts: Future applications of Microbubble-Ultrasound Interactions - Application of Ultrasound Contrast Agents in Thrombolysis
• Oral Abstract-Echocardiography in CAD: Extending Stress Echo Applications
• How to Session- Advanced Echo Doppler Techniques: Putting Them into Practice: Utility of Echocardiographic Contrast in Daily Practice
10/2009 Bubble Conference 2009 Advances in Contrast Ultrasound: Enhanced Atherosclerosis Imaging and Intervent
6/2009 2009 ASE Scientific Session
• Learning Lab Featuring ARS: Clinical Application of Contrast Echocardiography in Specific Populations (Sponsored by Lantheus Medical)
• Pulmonary Hypertension • Stress Perfusion Contrast Echocardiography: When and How
4/2009 2009 Family Practice Board Review – UNMC 3/2009 2009 ACC Scientific Sessions
• Clinical Application: Subclinical Artery Disease (Co-Chair) • Advances in Stress Echocardiography • Contrast Echocardiography Techniques to Detect Coronary Artery
Disease
2/2009 Cleveland Clinic Annual Symposium – Faculty Presenter 1/2009 14th European Symposium on Ultrasound Contrast Imaging, Rotterdam,
Netherlands – Faculty Presenter 1/2009 2009 ASE CONCERTO – Faculty Presenter 11/2008 2008 AHA Scientific Session – Abstract Moderator and Faculty Presenter
• Moderated E Poster - Echocardiography: Emerging Technologies in Contrast
09/2008 Invited Faculty Presenter at 23rd Annual Advances in Contrast Enhanced Atherosclerosis Imaging and Interventions - Bubble Course 2008
06/2008 2008 ASE Scientific Sessions – Faculty Presenter, Moderator, and Chair
• Moderator Myocardial Contrast Echocardiography • Myocardial Contrast Echocardiography - What is a Perfusion Defect in
MCE During Inotropic and Vasodilator Stress • Slow Bolus Perfusion Imaging for Resting Abnormalities • Myocardial Contrast Echocardiography (Co-Chair) • Contrast Echocardiography with FDA- Myocardial Opacification • Presentation: Integrative and Organ Systems Pharmacology Short Course
04/2008 Family Medicine Review Board – UNMC 03/2008 2008 ACC Scientific Sessions – Faculty Presenter, Moderator, and Imaging
Chair • Myocardial Contrast Echocardiography: Will It Ever Become Clinical
Reality? • Viability Perfusion
02/2008 2008 ASE CONCERTO Faculty Presenter 01/2008 13th European Symposium on Ultrasound Contrast Imaging, Rotterdam, Netherlands – Presenter
12/2007 Grand Rounds –Invited Presenter Richmond, VA 11/2007 2007 AHA Scientific Sessions – Moderator
08/2007 Invited Faculty Presenter at 22nd Annual Advances in Contrast Enhanced
Atherosclerosis Imaging and Interventions – Bubble Course 2007 06/2007 2007 ASE Scientific Session - Faculty Presenter
11/2006 Invited Faculty Presenter at the 21st Annual Advances in Contrast Ultrasound/Bubble Course in Chicago • “Improved detection of subendocardial wall thickening abnormalities during
dobutamine stress with real time perfusion myocardial contrast echocardiography”
10/2006 Invited Speaker to the Recent Advances in Echocardiography at the University of
Colorado in Denver • “Real time myocardial contrast perfusion imaging”
03/2006 Invited Visiting Professor Lecturer to University of Illinois
• “Therapeutic Implications of Ultrasound-Microbubble Interactions” 01/2006 11th European Symposium on Ultrasound Contrast Imaging, Rotterdam,
Netherlands. Presenter
COMMUNITY SERVICE: Board of Directors and Treasurer - Good News Bears Club (Inner City Youth Ministry) PUBLICATIONS: A. ARTICLES PUBLISHED IN SCHOLARLY JOURNALS: 1. Porter TR, Eckberg DL, Fritsch JM, Rea RF, Beightol LA, Schmedtje JF, Mohanty PK. Autonomic
pathophysiology in heart failure patients. J Clin Invest 1990;85:1362-1371. 2. Porter TR, Vetrovee GW. Reciprocal ECG changes in acute myocardial infarction andangiographic
correlation. Cath Cardiovasc Diag 1990;21:41-44. 3. Porter TR, Lenhart M, Arrowood J, Moskowitz W, Paulsen W, Lofland G, Nixon JV.Dissecting aortic
aneurysm eight years after aortic commissurotomy for congenital aortic stenosis: Detailed identification by transesophageal echocardiography. Am Heart J 1990;716-718.
4. Om A, Porter TR, Mohanty PK. Transesophageal echocardiographic diagnosis of acute aortic dissection complicating cocaine abuse. Am Heart J 1992;(123):532-534.
5. Porter TR, Ornato JP, Guard CS, Roy VG, Burns CA, Nixon JV. Transesophageal echocaridogrpahy to assess mitral value function and flow during cardiopulmonary resuscitation. Am J Cardiol 1992;70:1056-1060.
6. Porter TR, Taylor DO, Fields J, Cycan A, Akosah K, Mohanty PK, Pandian NG. Direct in vivo evaluation of pulmonary arterial pathology in chronic congestive heart failure with catheter-based intravascular ultrasound imaging. Am J Cardiol 1993;71:754-757.
7. Porter TR, D'Sa A, Turner C, Jones LA, Minisi AJ, Mohanty PK, Vetrovec GW, Nixon JV. Myocardial contrast echocardiography for the assessment of coronary blood-flow reserve: Validation in humans. J Am
Coll Cardiol 1993;21:349-355. 8. Akosah KO, Porter TR, Simon R, Funai JT, Minisi AJ, Mohanty PK. Ischemia-induced regional wall
motion abnormality is improved after coronary angioplasty: Demonstration by dobutamine stress echocardiography. J Am Coll Cardiol 1993;21:584-589.
9. Porter TR, D'Sa A, Pesko L, Turner C, Nath A, Vetrovec GW, Nixon JV. Usefulness of myocardial contrast echocardiography in detecting the immediate changes in anterograde blood flow reserve following coronary angioplasty. Am J Cardiol 1993;71:893-896.
10. Porter TR, Taylor DO, Cycan A. Endothelium-dependent pulmonary artery responses in chronic heart failure: Influence of pulmonary hypertension. J Am Coll Cardiol 1993;22:1418-1424.
11. Porter TR, Taylor DO, Pandian NG, Nixon JV, Vetrovec GW, Monhanty PK. Pulmonary arterial dynamics in congestive heart failure in humans: Significance of pulmonary arterial stiffness. J Vasc Med Biol 1993; Vol.4,2-3:105-114.
12. Porter TR, Pretlow R, D'Sa A, et al. In vitro study of the effects of volume changes on parameters of the radiofrequency amplitude versus time curve with sonicated albumin. J Am Soc Echocardiogr 1993;6:564-569.
13. Porter TR, Sears T, Xie F, Michels A, Mata J, Welsh D, Shurmur S. Intravascular ultrasound study of angiographically mildly diseased coronary arteries. J Am Coll Cardiol 1993;22:1858-1865.
14. Porter TR, Xie F, Anderson JR, Kricsfeld A, D’Sa A. Multifold sonicated dilutions of albumin with fifty percent dextrose improve left ventricular contrast videointensity after intravenous injection in human beings. J Am Soc Echocardiogr 1994;7:465-471.
15. Porter TR, Xie F, Kricsfeld A, Chiou A, Dabestani A. Improved endocardial border resolution during dobutamine stress echocardiography with intravenous sonicated dextrose albumin. J Am Coll Cardiol 1994;23:1440-443.
16. Porter TR, Radio SJ, Anderson JA. Composition of coronary atherosclerotic plaque in the intima and media affects intravascular ultrasound measurements of intimal thickness. J Am Coll Cardiol 1994;23:1079-1084.
17. Olson CE, Porter TR, Deligonul U, Xie F, Anderson JR. Left ventricular volume changes during dobutamine stress echocardiography identify patients with more extensive coronary artery disease. J Am Coll Cardiol 1994;24:1268-1273.
18. Porter TR, Mohanty PK, Pandian NG. Intravascular ultrasound imaging of pulmonary arteries: Methodology, clinical applications, and future potential. Chest 1994;106:1551-1557.
19. Shurmur SW, Deligonul U, Rayner RW, Sears TW, Porter TR. Transverse coronary dissection resulting in abrupt vessel closure following directional coronary atherectomy: Clinical, angiographic, and intracoronary ultrasound findings. Catheterization and Cardiovascular Diagnosis 1994;32:174-177.
20. Akosah KO, Funai JT, Porter TR, Jesse RJ. Left atrial appendage contractile function in atrial fibrillation. Influence of heart rate and cardioversion to sinus rhythm. Chest 1995;690-696.
21. Porter TR, Xie F. Visually discernible myocardial echocardiographic contrast after intravenous injection of sonicated dextrose albumin microbubbles containing high molecular weight, less soluble gases. J Am Coll Cardiol 1995;25:509-515.
22. Porter TR, Xie F, Kilzer K. Intravenous perfluoropropane-exposed sonicated dextrose albumin produces myocardial ultrasound contrast which correlates with coronary blood flow. J Am Soc Echocardiogr 1995;8:710-718.
23. Porter TR, Xie F, Kricsfeld A, Kilzer K. Non-invasive identification of acute myocardial ischemia and reperfusion with contrast ultrasound using intravenous perfluoropropane-exposed sonicated dextrose albumin. J Am Coll Cardiol 1995;26:33-40.
24. Porter TR, Xie F, Kricsfeld A. The mechanism and clinical implication of improved left ventricular videointensity following intravenous injection of multi-fold dilutions of albumin with dextrose. Intl J Cardiac Imaging 1995;11:117-125.
25. Wong C, Porter TR, Xie F, Deligonul U. Segmental analysis of coronary arteries with equivalent plaque burden by intravascular ultrasound in patients with and without angiographically significant coronary artery disease. Am J Cardiol 1995;76:598-601.
26. Porter TR, Xie F. Transient myocardial contrast after initial exposure to diagnostic ultrasound pressures with minute doses of intravenously injected microbubbles: Demonstration and potential mechanisms. Circulation 1995;92:2391-2395.
27. Wong CB, Porter TR. Cardiac management of patients undergoing major noncardiac surgery. Nebraska Medical Journal 1995;80:350-354.
28. Porter TR, Xie F, Kricsfeld A, Deligonul U, Kilzer K, Kricsfeld D. Myocardial perfusion abnormalities during low dose dobutamine after coronary reperfusion can be demonstrated with Intravenous perfluorocarbon-exposed sonicated dextrose albumin ultrasound contrast. Am Heart J 1996;131:1079-1087.
29. Porter TR, Xie F, Kricsfeld A, Deligonul U, Kilzer K. Reduction in left ventricular cavity attenuation and improvement in posterior myocardial contrast with higher molecular weight intravenous perfluorocarbon-exposed sonicated dextrose albumin microbubbles. J Am Soc Echocardiogr 1996;9:437-441.
30. Porter TR, Xie F, Kricsfeld D, Armbruster R. Improved myocardial contrast with second harmonic transient ultrasound response imaging in humans using intravenous perfluorocarbon-exposed sonicated dextrose albumin. J Am Coll Cardiol 1996;27:1497-1501.
31. Porter TR, Xie F, Li S, D’Sa A, Rafter P. Increased ultrasound contrast and decreased microbubble destruction rates with triggered ultrasound imaging. J Am Soc Echocardiogr 1996;9:599-605.
32. Porter TR, LeVeen R, Fox R, Kricsfeld A, Xie F. Thrombolytic enhancement with perfluorocarbon-exposed sonicated dextrose albumin microbubbles. Am Heart J 1996;132:964-968.
33. Porter TR, Iversen PL, Li S, Xie F. Interaction of diagnostic ultrasound with synthetic oligonucleotide-labeled perfluorocarbon-exposed sonicated dextrose albumin microbubbles. J Ultrasound Med 1996;15:577-584.
34. Porter TR, Xie F, Kilzer K, Deligonul U. Detection of myocardial perfusion abnormalities during dobutamine and adenosine stress echocardiography with transient myocardial contrast imaging after minute quantities of intravenous perfluorocarbon-exposed sonicated dextrose albumin. J Am Soc Echocardiogr 1996;9:779-786.
35. Porter TR, Kricsfeld A, Deligonul U, Xie F. Detection of regional perfusion abnormalities during adenosine stress echocardiography with intravenous perfluorocarbon-exposed sonicated dextrose albumin. Am Heart J 1996;132:41-47.
36. Smith M, Beightol L, Fritsch-yelle J, Ellenbogen K, Porter TR, Eckberg D. Valsalva’s Maneuver Revisited: A quantitative method yielding insights into human autonomic control. Am J Physiol 1996;271 (Heart Circ Physiol 40):H1240-249.
37. Smith ML, Beightol LA, Fritsch-Yelle JM, Ellenbogen KA, Porter TR, Eckberg DL. Valsalva’s maneuver revisited: a quantitative method yielding insights into human autonomic control. Am J of Physiol 1996;271:H1240-9.
38. Porter TR, Kricsfeld D, Cheatham S, Li S. The effect of ultrasound frame rate on perfluorocarbon-exposed sonicated dextrose albumin microbubble size and concentration when insonifying at different flow rates, transducer frequencies, and acoustic outputs. J Am Soc Echocardiogr 1997;10:593-601.
39. Porter TR, Li S, Kricsfeld D, Armbruster R. Detection of myocardial perfusion in multiple echocardiographic windows with one intravenous injection of microbubbles using transient response second harmonic imaging. J Am Coll Cardiol 1997;29:791-799.
40. Porter TR, Xie F, Li S. Differences in Myocardial Contrast Produced with Transient Response Imaging When Using Intravenous Microbubbles Containing Gases of Different Molecular Weight. Echocardiography 1997;14:441-446.
41. Porter TR, Li S, Kilzer K, Deligonul U. The Effect of Significant Two Vessel Versus One Vessel Coronary Artery Stenosis on Myocardial Contrast Defects Observed with Intermittent Harmonic Imaging Following Intravenous Contrast During Dobutamine Stress Echocardiography. J Am Coll Cardiol 1997;30:1399-1406.
42. Porter TR, Li S, Kilzer K. Smaller intravenous perfluorocarbon-containing microbubbles produce greater myocardial contrast with intermittent harmonic imaging and better delineation of risk area during acute myocardial ischemia. J Am Soc Echocardiogr 1997;10:792-797.
43. Porter TR, Transient response during contrast echocardiography. Advances in Cardiac Echo-Contrast
1997;5:47-55. 44. Porter TR, Li S, Kilzer K, Deligonul U. Correlation Between Quantitative Angiographic Lesion Severity
and Myocardial Contrast Intensity During a Continuous Infusion of Perfluorocarbon Containing Microbubbles. J Am Soc Echocardiogr 1998:11:702-710.
45. Porter TR, Li S, Oster R, Deligonul U. The clinical implications of no-reflow demonstrated with intravenous perfluorocarbon containing microbubbles following restoration of TIMI 3 in patients with acute myocardial infarction. Am J Cardiol 1998;82:1173-1177.
46. Birnbaum Y, Luo H, Nagai T, Fishbein MC, Peterson TM, Li S, Kricsfeld D, Porter TR, Siegel RJ. Noninvasive in Vivo Clot Dissolution Without a Thrombolytic Drug: Recanalization of Thrombosed Iliofemoral Arteries by Transcutaneous Ultrasound Combined with Intravenous Infusion of Microbubbles. Circulation 1998;97:130-134.
47. Porter T, Kricsfeld D, Cheatham S, Li S. Effect of Blood and Microbubble Oxygen and Nitrogen Content on Perfluorocarbon-filled Dextrose Albumin Microbubble Size and Efficacy: In Vitro and in Vivo Studies. J Am Soc Echocardiogr 1998;11:421-425.
48. Porter TR. Harmonic Ultrasound Imaging During Routine and Contrast-Enhanced Echocardiography. Cardiac Ultrasound TODAY 1998;4(8):121-136.
49. Porter T, Xie F, Li S, Kricsfeld D, Deligonul U. Effect of Transducer Standoff on the Detection, Spatial Extent, and Quantification of Myocardial Contrast Defects Caused by Coronary Stenoses. J Am Soc Echocardiogr 1999;12:951-60.
50. Porter TR, Li S, Jiang L, Grayburn P, Deligonul U. Real Time Visualization of Myocardial Perfusion and Wall Thickening in Humans with Intravenous Ultrasound Contrast and Accelerated Intermittent Harmonic Imaging. J Am Soc Echocardiogr 1999;12:266-271.
51. Tiemann K, Lohmeier S, Kuntz S, Koster J, Pohl C, Burns P, Porter T, Nanda N, Luderitz B, Becher H. Real-Time Contrast Echo Assessment of Myocardial Perfusion at Low Emission Power- First Experimental and Clinical Results Using Power Pulse Inversion Imaging. Echocardiography 1999;16:799-809.
52. Arruda ALM, Ozorio A, Mattos E, de Andreade JS, Porter T, Mathias W, Hypoperfusion of the Left Ventricle in the Absence of Changes in Segmental Contractility as Observed through Echocardiography by Using Microbubbles During Dobutamine Infusion. Arq Bras Cardiol 1999;72:722-726.
53. Porter TR, Shouping L, Kilzer K, Deligonul U. Effect of a Residual Stenosis by Quantitative Angiography on the Myocardial Contrast Defect Observed Following Coronary Reperfusion Using Intermittent Harmonic Ultrasound Imaging and Intravenous Perfluorocarbon Ultrasound Contrast. Echocardiography 1999;16:785-797.
54. Mukherjee D, Wong J, Griffin B, Ellis SG, Porter T, Sen S, Thomas JD. Ten Fold Augmentation of Myocardial Uptake of Vascular Endothelial Growth Factor with Ultrasound after Systemic Administration. J Am Coll Cardiol May 2000;35:1678-1686.
55. Cwaig J, Xie F, O’Leary E, Kricsfeld D, Dittrich H, Porter TR. Detection of Angiographically Significant Coronary Artery Disease with Accelerated Intermittent Imaging after Intravenous Administration of Ultrasound Contrast Material. Am Heart J 2000;139:675-683.
56. Porter TR. Improving the Evaluation of Left Ventricular Systolic Function with Intravenous Perfluorocarbon Ultrasound Contrast: Will Suboptimal Echocardiograms Become an Endangered Species? J Am Coll Cardiol February 2000;35:491-2.
57. Porter TR. Stress Contrast Echocardiography. Cardiac Ultrasound TODAY 2000;6:19-31. 58. Porter TR. Role of Intravenous Ultrasound Contrast in Stress Echocardiography. Echocardiography
2000;17:92-9. 59. Porter TR, Xie F. Applications of Contrast Echocardiography to Ischemic Heart Disease. The Circulation
Frontier 2000;4:42-51. 60. Mulvagh SL, DeMaria AN, Feinstein SB, Burns PN, Kaul S, Miller JG,Monaghan M, Porter TR, Shaw LJ,
Villanueva FS. Contrast Echocardiography Current and Future Applications.American Society of Echocardiography Task Force on Standards and Guidelines for the Use of Ultrasonic Contrast in Echocardiography. Contrast Echocardiography: J Am Soc Echocardiogr 2000;13:331-342.
61. Porter TR, Cwajg J. Myocardial Contrast Echocardiography: A New Gold Standard for Perfusion
Imaging? Echocardiography 2001;18:79-87. 62. Culp WC, Porter TR, Xie F, Goertzen TC, McCowan TC, Vonk BN et al. Microbubble potentiated
ultrasound as a method of declotting thrombosed dialysis grafts: experimental study in dogs. Cardiovasc Intervent Radiol 2001; 24:407-412.
63. Shimoni S, Zoghbi W, Xie F, Kricsfeld D, Iskander S, Gobar L, Mikati I, Abukhalil J, Verani M, O’Leary E, Porter TR. Real-Time Assessment of Myocardial Perfusion and Wall Motion During Bicycle and Treadmill Exercise Echocardiography: Comparison With Single Photon Emission Computed Tomography. J Am Coll Cardiol 2001;37:741-47.
64. Porter TR, Xie F, Silver M, Kricsfeld D, O’Leary E. Real-Time Perfusion Imaging With Low Mechanical Index Pulse Inversion Doppler Imaging. J Am Coll Cardiol 2001;37:748-53.
65. Porter TR, Hiser WL, Kricsfeld D, Deligonul U, Xie F, Iversen P, Radio S. Inhibition of Carotid Artery Neointimal Formation with Intravenous Microbubbles. UltrasoundMedBiol 2001;27:259-265.
66. Porter, TR, Xie, F. Therapeutic Ultrasound for Gene Delivery. Echocardiography, 2001;18:349-353. 67. Klein, AL, Grimm, RA, Murray, RD, Apperson-Hansen, C, Asinger, RW, Black, IW, Davidoff, R, Erbel, R,
Halperin, JL, Orsinelli, DA, Porter, TR, Stoddard, MF. Use of Transesophageal Echocardiography To Guide Cardioversion In Patients With Atrial Fibrillation. New England Journal of Medicine 2001;344:1411-20.
68. Porter, TR, Xie, F. Contrast Echocardiography: How Will It Be Used. ACC Current Journal Review 2001;10:43-47.
69. Porter TR, Everbach C, Kricsfeld D, Xie F. Myocardial Cavitational Activity During Continuous Infusion and Bolus Intravenous Injections of Perfluorocarbon-Containing Microbubbles. J Am Soc Echocardiogr 2001;14:618-625.
70. Porter, TR, Xie, F. Ultrasound, Microbubbles, and Thrombolysis. Prog CardiovascDis 2001;44:101-110. 71. Porter T, Kricsfeld D, Lof J, Everbach EC, Xie F. Effectiveness of Transcranial and Transthoracic
Ultrasound and Microbubbles in Dissolving Intravascular Thrombi. Ultrasound Med 2001;20:1313-1325. 72. Culp WC, Porter TR, Xie F, Goertzen TC, McCowan TC, Vonk BN, Baxter BT. Microbubble Potentiated
Ultrasound as a Method of Declotting Thrombosed Dialysis Grafts: Experimental Study in Dogs. Cardiovasc Intervent Radiol 2001;24:407-412.
73. Mathias W, Arruda AL, Andrade JL, Filho OC, Porter T. Endocardial Border Delineation During Dobutamine Infusion Using Contrast Echocardiography. Echocardiography 2002;19:109-114.
74. Ronderos RE, Boskis M, Chung N, Corneli DB, Escudero EM, Ha JW, Charlante C, Rim S-J, Portis M, Fabris N, Camilletti J, Mele AA, Otero F, Porter TR. Correlation between Mycardial Perfusion Abnormalities Detected with Intermittent Imaging Using Intravenous Perfluorocarbon Microbubbles and Radioisotope Imaging during High-Dose Dipyridamole Stress Echo. Clin Cardiol 2002;25:103-111.
75. Porter TR, Xie F. Part II: Recent Advances in Myocardial Contrast Echocardiography, Clinical Experience in the Detection of Coronary Artery Disease with Myocardial Contrast Echocardiography. Echocardiography 2002;19:399-407.
76. Khankirawatana B, Khankirawatana S, Lof J, Porter T. Left Atrial Volume Determination by Three-Dimensional Echocardiography Reconstruction: Validation and Application of a Simplified Technique. J Am Soc Echocardiogr 2002;15:1051-6.
77. Culp WC, Porter TR, Culp Jr, WC, Vonk BN. Carbon Dioxide in the Aortic Arch: Swine Studies of Detection, Hemodynamics, Physiologic Implications, and Rescue Maneuvers. Cardiovasc Intervent Radiol. 2003;26:128-135
78. Culp W, Porter TR, McCowan TC, Roberson PK, James CA, Matchett WJ, Moursi M. Microbubble-augmented Ultrasound Declotting of Thrombosed Arteriovenous Dialysis Grafts in Dogs. J Vasc Interv Radiol 2003;14:343-347.
79. Sonne C, Xie F, Lof J, Oberdorfer J, Phillips P, Everbach EC, Porter TR. Differences in Definity and Optison Microbubble Destruction Rates at a Similar Mechanical Index with Different Real Time Perfusion Systems. J Am Soc Echocardiogr 2003;16:1178-85.
80. Porter TR, McGrain A, Oehlke H, Xie F. Should the Dobutamine Stress Test Include Myocardial Contrast Echocardiography? Cardiac Ultrasound TODAY 2003;9(2):27-34.
81. Culp WC, Porter TR, Culp WC Jr, Vonk BN. Carbon Dioxide in the Aortic Arch: Coronary Effects and Implications in a Swine Study. Cardiovasc Intervent Radiol 2003;26:128-135.
82. Porter TR, Oberdorfer J, Rafter P, Lof J, Xie F. Microbubble Responses to the Similar Mechanical Index with Different Real Time Perfusion Imaging Techniques. US Med Biol 2003;29:1187-1192.
83. Porter TR, O’Leary E, Silver M, Oehlke H, Xie F. A Method of Detecting and Quantifying Severity of Myocardial Perfusion Defects With Intravenous Ultrasound Contrast and Breath Holding During Stress Echocardiography. Echocardiography 2003;20:411-422.
84. Elhendy A, Windle J, Porter TR. Safety and Feasibility of Dobutamine Stress Echocardiography in Patients with Implantable Cardioverter Defibrillator. Am J Cardiol 2003;92:475-477.
85. Stambler BS, Ellenbogen KA, Zhang X, Porter TR, Xie F, Malik R, Small R, Burke M, Kaplan A, Nair L, Belz M, Fuenzalida C, Gold M, Love C, Sharma A, Silverman R, Sogade F, Van Natta B, Wilkoff BL. Right Ventricular Outflow Versus Apical Pacing In Pacemaker Patients With Congestive Heart Failure And atrial Fibrillation. Journal of Cardiovascular Electrophysiology 2003;14:1180-1186.
86. Kipshidze N, Porter TR, Dangas G, Yazdi H, Tio F, Xie F, Hellinga D, Fournadijev J, Wolfram R, Seabron R, Waksman R, Abizaid A, Roubin G, Iyer S, Leon MB, Iversen P, Moses JW. Systemic Targeted Delivery Of Antisense With Perflourobutane Gas Microbubble Carrier Reduced Neointimal Formation In The Porcine Coronary Restonsis Model. Cardiovascular Radiation Medicine 2003;4:152-9.
87. Khankirawatana B, Khankirawatana S, Porter TR. How Should Left Atrial be Reported? Comparative Assessment with Use of Multiple Echocardiographic Methods. Am Heart J 2004;147:369-74.
88. Elhendy A, O’Leary E, Xie F, McGrain A, Porter TR. Comparative Accuracy of Real Time Myocardial Contrast Perfusion Imaging and Wall Motion Analysis During Dobutamine Stress Echocardiography for the Diagnosis of Coronary Artery Disease. J Am Coll Cardiol 2004;44 2185-2191.
89. Khankirawatana B, Khankirawatana S, Peterson B, Oehlke H, Porter TR. Peak Atrial Systolic Mitral Annular Velocity by Dopple Tissue Reliably Predicts Left Atrial Systolic Function. J Am Soc Echocardiogr. 2004;17:353-360.
90. Unger EC, Porter TR, Culp William, Labell R, Matsunaga T, Zutshi R. Therapeutic applications of lipid-coated microbubbles. J. Advanced Drug Delivery Reviews 2004;56: 1291-1314.
91. Tsutsui JM, Porter TR. Diagnostic Applications of Intravenous Microbubbles. Cardiac Ultrasound TODAY 2004;10:35-46.
92. Tsutsui JM, Xie F, Cano M, Chomas J, Phillips P, Radio SJ, Lof J, Porter TR. Detection of retained microbubbles in carotid arteries with real-time low mechanical index imaging in the setting of endothelial dysfunction. J Am Coll Cardiol 2004; 44:1036-1046
93. Culp W C, Porter T R, Lowery J, Xie F, Roberson PK, Marky L. Intracranial Clot Lysis with Intravenous Microbubbles and Transcranial Ultrasound in Swine. Stroke 2004;35:2407-2411
94. Khankirawatana B, Khankirawatana S, Mahrous H, Porter TR. Assessment of papillary muscle function using myocardial velocity gradient derived from tissue Doppler echocardiography. Am J Cardiol 2004; 93: 45-49.
95. Tsutsui JM, Grayburn PA, Xie F, Porter TR. Drug and gene delivery and enhancement of thrombolysis using ultrasound and microbubbles. Cardiol Clin 2004; 22:299-312.
96. Tsutsui JM, Xie F, Porter TR. The use of microbubbles to target drug delivery. Cardiovascular Ultrasound 2004; 2:23.
97. Elhendy A, O’leary EL, Xie F, McGrain AC, Anderson JR, Porter TR. Comparative accuracy of real-time myocardial contrast perfusion imaging and wall motion analysis during dobutamine stress echocardiography for the diagnosis of coronary artery disease. J Am Coll Cardiol 2004;44:2185-91.
98. Khankirawatana B, Khankirawatana S, Peterson B, Mahrous H, Porter TR. Peak atrial systolic mitral annular velocity by Doppler tissue reliably predicts left atrial systolic function. J Am Soc Echocardiogr 2004;17:353-60.
99. Elhendy A, Ginete W, Shurmur S, Porter TR. Acute myocardial infarction after a negative dobutamine stress echocardiogram. Eur J Echocardiography. 2004;5:469-471.
100. Tsutsui J, Xie F, O’Leary EL, Elhendy A, Anderson JR, McGrain AC, Porter TR. “Diagnostic Accuracy and Prognostic Value of Dobutamine Stress Myocardial Contrast Echocardiography in Patients with
Suspected Acute Coronary Syndromes”. Echocardiography. 2005; 22:487-496. 101. Tsutsui JM, Xie F, McGrain AC, Mahrous H, Hankins J, O’Leary EL, Porter TR. Comparison of Low-
Mechanical Index Pulse Sequence Schemes for Detecting Myocardial Perfusion Abnormalities During Vasodilator Stress Echocardiography. Am J Cardiol 2005; 95:565-570.
102. Tsutsui JM, Elhendy A, Xie F, O’Leary EL, McGrain AC, Porter TR. Safety of dobutamine stress real-time myocardial contrast echocardiography. J Am Coll Cardiol 2005; 45:1235-42.
103. Kipshidze NN, Porter TR, Dangas G, Yazdi H, Tio F, Xie F, Hellinga D, Wolfram R, Seabron R, Waksman R, Abizaid A, Roubin G, Iyer S, Colombo A, Leon MB, Moses, J. Novel Site-Specific Systemic Delivery of Rapamycin with Perfluorobutane Gas Microbubble Carrier Reduced Neointimal Formation in a Porcine Coronary Restenosis Model. Catheter Cardiovasc Interv. 2005;64:389-394.
104. Tsutsui J, Elhendy A, Anderson JR, Xie F, McGrain AC, Porter TR. Prognostic Value of Dobutamine Stress Myocardial Contrast Perfusion Echocardiography. Circulation 2005;112:1444-50.
105. Xie F, Tsutsui JM, Lof J, Unger EV, Johanning J, Culp WC, Matsunaga T, Porter TR. Effectiveness of Lipid Microbubbles and Ultrasound in Declotting Thrombosis. Ultrasound Med Bio 2005;31:979-985.
106. Chapman S, Windle J, Xie F, McGrain A, Porter TR. Incidence of Cardiac Arrhythmias with Therapeutic Versus Diagnostic Ultrasound and Intravenous Microbubbles. J Ultrasound Med 2005; 24:1099-1107.
107. Elhendy A, Tsutsui JM, O’leary EL, Xie F, McGrain AC, Porter TR. Noninvasive diagnosis of coronary artery disease in patients with diabetes by dobutamine stress real-time myocardial contrast perfusion imaging. Diabetes Care. 2005;28:1662-7.
108. Tsutsui JM, Kusler M, Porter TR. Intravenous myocardial contrast echocardiography for the diagnosis of coronary artery disease. Curr Opin Cardiol 2005;20:381-5.
109. Xie F, Tsutsui JM, McGrain AC, Demaria A, Cotter B, Becher H, Lebleu C, Labovitz A, Picard MH, O’leary EL, Porter TR. Comparison of dobutamine stress echocardiography with and without real-time perfusion imaging for detection of coronary artery disease. Am J Cardiol 2005;96:506-11.
110. Elhendy A, Chapman S, Porter TR, Windle J. Association of Myocardial Ischemia with Mortality and Implantable Cardioverter Defibrillator Therapy in Patients with Coronary Artery Disease at Risk of Arrhythmic Death. J Am Coll Cardiol. 2005;46:1721-6.
111. Porter TR. Diagnostic and Therapeutic Utilization of Microbubbles. Acta Cardiol Sin 2005;21:77-88. 112. Elhendy A, Porter TR. Assessment of myocardial perfusion with real-time myocardial contrast
echocardiography: Methodology and clinical applications. J Nucl Cardiol. 2005;12:582-90. 113. Tsutsui JM, Elhendy A, Xie F, O’Leary E, McGrain AC, Porter TR. . J Am Coll Cardiol. 2005;46:1063-4. 114. Tsutsui JM, Mukherjee S, Elhendy A, Xie F, Lyden ER, O’Leary E, McGrain AC, Porter TR. Value of
Dobutamine Stress Myocardial Contrast Perfusion Echocardiography in Patients with Advanced Liver Disease. Liver Transplantation 2006;12:592-599.
115. Porter TR, Xie F, Knapp D, Iversen P, Marky LA, Tsutsui JM, Maiti S, Lof J, Radio S, Kipshidze NN. Targeted Vascular Delivery of Antisense Molecules Using Intravenous Microbubbles. Cardiovasc Revasc Med 2006;7:25-33.
116. Klein AL, Grimm RA, Jasper SE, Murray RD, Apperson-Hansen C, Lieber EA, Black IW, Davidoff R, Erbel R, Halperin JL, Orsinelli DA, Porter TR, Stoddard MF. “Efficacy of transesophageal echocardiography-guided cardioversion of patients with atrial fibrillation at 6 months: a randomized controlled trial.” Am Heart J 2006;151:380-9.
117. Porter TR, Airey K, Quader M. Mitral valve endocarditis presenting as complete heart block. Tex Heart Inst J 2006;33:100-1.
118. Tsutsui JM, Xie F, Johanning J, Lof J, Cory B, Thomas L, Matsunaga T, Unger E, Porter TR. Treatment of Deeply Located Acute Intravascular Thrombi with Low Frequency Guided Ultrasound and Intravenous Microbubbles. J Ultrasound Med 2006;25:1161-8.
119. Elhendy A, Porter TR. Myocardial contrast quantitation during stress echocardiography. Eur J Echocardiogr 2006;7:185-6.
120. Elhendy A, Tsutusi JM, O’Leary EL, Xie F, Majeed F, Porter TR. Evaluation of restenosis and extent of coronary artery disease in patients with previous percutaneous coronary interventions by dobutamine stress real-time myocardial contrast perfusion imaging. Heart 2006;92:1480-3.
121. Dijkmans PA, Senior R, Becher H, Porter TR, Wei K, Visser CA, Kamp O. Myocardial Contrast Echocardiography Evolving as a Clinically Feasible Technique for Accurate, Rapid, and Safe Assessment of Myocardial Perfusion. The Evidence So Far. J Am Coll Cardiol 2006;48:2168-2177.
122. Elhendy A, Tsutsui JM, O’Leary EL, Xie F, Porter TR. Noninvasive diagnosis of coronary artery bypass graft disease by dobutamine stress real-time myocardial contrast perfusion imaging. J Am Soc Echocardiogr 2006;19:1482-1487.
123. Majeed F, Porter TR, Tarantolo S, Duhachek-Stapelman A, Xie F, Elhendy A. Carcinoid crisis and reversible right ventricular dysfunction after embolization in untreated carcinoid syndrome. Eur J Echocardiogr 2007;8(5):386-9.
124. Xie F, Tsutsui JM, Gao L, Zucker IH, Porter TR. Interactions of Transthoracic Ultrasound and Intravenous Microbubbles with Cardiac Mechanoreceptors. Ultrasound in Med & Bio 2007;33:136-144.
125. Anderson D, Tsutsui JM, Xie, Radio S, Porter TR. The Role of Complement in the Adherence of Microbubbles to Dysfunctional Arterial Endothelium and Atherosclerotic Plaque. Cardiovasc Res 2007;73:597-606.
126. Porter TR. Cardiovascular imaging of remote myocardial ischemia: detecting a molecular trace of evidence left behind. Circulation 2007;115:292-3.
127. Xie F, Hankins J, Mahrous H, Porter TR. Detection of Coronary Artery Disease with a Continuous Infusion of Definity Ultrasound Contrast during Adenosine Stress Real Time Perfusion Echocardiography. Echocardiography 2007;24(10):1044-1050.
128. Porter,T., Xie,F. “Emerging cardiovascular imaging techniques to non-invasively detect coronary artery disease.” Expert Opinion on Medical Diagnostics 2007;1(2):203-211.
129. Tsutsui JM, Xie F, Cloutier D, Kalvaitis S, Elhendy A, Porter TR. “Real-time dobutamine stress myocardial perfusion echocardiography predicts outcome in the elderly.” Eur Heart J. 2008 Feb;29(3):377-85
130. Xie F, Dodla S, O’Leary E, Porter TR. “Detection of Subendocardial Ischemia in the Left Anterior Descending Coronary Artery Territory With Real-Time Myocardial Contrast Echocardiography During Dobutamine Stress Echocardiography.” J Am Coll Cardiol Img 2008; 1:271-278
131. Dolan MS, Gala S, Dodla S, Abdelmoneim SS, Xie F, Cloutier D, Bierig M, Mulvagh SL, Porter TR, Labovitz AJ. “Safety and Efficacy of Commercially Available Ultrasound Contrast Agents for Rest and Stress Echocardiography: A Multi-Center Experience.” J Am Coll Cardiol 2009;53:32-8
132. Xie F, Boska MD, Lof J, Uberti MG, Tsutsui JM, Porter TR. “Effects of Transcranial Ultrasound and Intravenous Microbubbles on Blood Brain Barrier Permeability in a Large Animal Model.” Ultrasound Med Biol 2008 Dec;34(12):2028-34. Epub 2008 Aug 9.
133. Wei K, Mulvagh SL, Carson L, Davidoff R, Gabriel R, Grimm RA, Wilson S, Fane L, Herzog C, Zoghbi WA, Taylor R, Farrar M, Chaudhry FA, Porter TR, Irani W, Lang R. “The Safety of Definity and Optison for Ultrasound Image Enhancement: A Retrospective Analysis of 78,383 Administered Contrast Doses.” J Am Soc Echocardiogr 2008 Nov;21(11):1179-20
134. Mulvagh SL, Rakowski H, Vannan MA, Abdelmoneim SS, Becher H, Bierig SM, Burns PN, Castello R, Coon PD, Hagen ME, Jollis JG, Kimball TR, Kitzman DW, Kronzon I, Labovitz AJ, Lang RM, Mathew J, Moir WS, Nagueh SF, Pearlman AS, Perez JE, Porter TR, Rosenbloom J, Strachan GM, Thanigaraj S, Wei K, Woo A, Yu EH, Zoghbi WA; American Society of Echocardiography. “American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography.” J Am Soc Echocardiogr. 2008 Nov;21(11):1179-201. Epub 2008 Oct 10.
135. Slikkerverr J, Dijkmans PA, Sieswerda GT, Doevendans P, van Dijk A, Verheugt F, Porter TR, Kamp O. “Ultrasound enhanced prehospital thrombolysis using microbubbles infusion in patients with acute ST elevation myocardial infarction: rationale and design of the Sonolysis study.” Trials 2008 Dec 10;9:72.
136. Xie F, Lof J, Matsunaga T, Zutshi R, Porter TR. “Diagnostic ultrasound combined with glycoprotein IIb/IIa targeted microbubbles improves microvascular recovery after acute coronary thrombotic occlusions.” Circulation. 2009;119:1378-85.
137. Dodla S, Xie F, Smith M, O’Leary E, Porter TR. “Real time perfusion echocardiography during treadmill exercise and dobutamine stress testing.” Heart. 2010;96:220-5. epub 2009 Aug.
138. Xie F, Lof J, Everbach C, He A, Bennett RM, Matsunaga T, Johanning J, Porter TR. “Treatment of acute
intravascular thrombi with diagnostic ultrasound and intravenous microbubbles.” JACC Cardiovasc Imaging. 2009. 2:511-518.
139. Porter TR. “The ulitization of ultrasound and microbubbles for therapy in acute conronary syndromes.” Cardiovasc Res. 2009.83:636-42.
140. Porter TR. “Capillary blood flow abnormalities in the skeletal muscle and microvascular complications in diabetes lessons that cannot be learned from larger vessels.” J Am Coll Cardiol. 2009;53:2184-5.
141. Porter TR, Xie F. Myocardial perfusion imaging with contrast ultrasound. JACC Cardiocasc Imaging. 2010;3:176-87.
142. Kutty S, Xie F, Gao S, Drvol LK, Lof J, Fletcher SE, Radio SJ, Danford DA, Hammel JM, Porter TR. Sonothrombolysis of intra-catheter aged venous thrombi using microbubble enhancement and guided three-dimensional ultrasound pulses. J Am Soc Echocardiogr 2010; 23:1001-6.
143. Anderson DR, Duryee MJ, Anchan RK, Garvin RP, Johnston MD, Porter TR, Thiele GM, Klassen LW. Albumin-based microbubbles bind up-regulated scavenger receptors following vascular injury. J Biol Chem 2010;285:40645-53.
144. Labovitz AJ, Noble VE, Bierig M, Goldstein SA, Jones R, Kort S, Porter TR, Spencer KT, Tayal VS, Wei K. Focused cardiac ultrasound in the emergent setting: a consensus statement of the American Society of Echocardiography and American College of Emergency Physicians. J Am Soc Echocardiogr 2010;23:1225-30.
145. Shi WT, Gao S, Vignon F, Powers JE, Drvol L, Ki Won J, Xie F, Lof J, Everbach EC, Porter TR. Investigation of effectiveness of microbubble stable cavitation in thrombolysis. IEEE Int Ult Sym IUS 2010:330-333.
146. Vignon F, Shi W, Liu J, Xie F, Gao S, Drvol L, Lof J, Everbach EC, Porter TR, Powers J. In Vivo Microbubble Cavitation Imaging. IEEE Int Ult Sym, IUS 2011:927-930
147. Shi WT, Porter TR, Vignon F, Powers JE, Gao S, Liu J, Xie F, Drvol L, Lof J, Everbach EC.Investigation of Image-guided sonothrombolysis ina porcine acute ischemic stroke model. IEEE Int Ult Sym IUS 2011:5-8.
148. Xie F, Everbach EC, Gao S, Brvol LK, Shi WT, Vignon F, Powers JE, Lof J, Porter TR. Effects of attenuation and thrombus age on the success of ultrasound and microbubble-mediated thrombus dissolution. Ultrasound Med Biol 2011;37:280-8.
149. Kaul S, Miller JG, Grayburn PA, Hashimoto S, Hibberd M, Holland MR, Houle HC, Klein AL, Knoll P, Lang RM, Lindner JR, McCulloch ML, Metz S, Mor-Avi V, Pearlman AS, Pelikka PA, DeMars Plambeck N, Prater D, Porter TR, Sahn DJ, Thomas JD, Thomenius KE, Weissman NJ. J Am Soc Echocardiogr 2011;24:455-64.
150. Hsiao SH, Chiou KR, Porter TR, Huang WC, Lin SK, Kuo FY, Cheng CC, Lin KL, Lin SL. Left atrial parameters in the estimation of left ventricular filling pressure and prognosis in patients with acute coronary syndrome. Am J Cardiol. 2011;107:1117-24.
151. Porter TR, Adolphson M, High RR, Smith LM, Olson J, Erdkamp M, Xie F, O’Leary E, Wong BF, Eifert-Rain S, Hagen ME, Abdelmoneim SS, Mulvagh SL. Rapid detection of coronary artery stenoses with real-time perfusion echocardiography during regadenoson stress. Circ Cardiovasc Imaging 2011;4:628-35.
152. Xie F, Slikkerverr J, Gao S, Lof J, Kamp O, Unger E, Radio S, Matsunaga T, Porter TR. Coronary and microvascular thrombolysis with guided diagnostic ultrasound and microbubbles in acute ST segment elevation myocardial infarction. J Am Soc Echocardiogr 2011;24:1400-8
153. Kutty S, Olson J, Danford CJ, Sandene EK, Xie F, Fletcher SE, Erickson CC, Kugler JD, Danford DA, Porter TR. Ultrasound contrast and real-time perfusion in conjunction with supine bicycle stress echocardiography for comprehensive evaluation of surgically corrected congenital heart disease. PLoS ONE 2012;7(12): e51453
154. Poterucha JT, Haglund NA, Um JY, Porter TR, Dutmitru I. Dynamic pulmonary artery obstruction causing right ventricular failure after cardiac transplantation in a patient with mustard-senning corrected d-transposition of the great arteries. Congenit Heart Dis 2012;7:247-52.
155. Slikkerveer J, Kleijn SA, Appleman Y, Porter TR, Veen G, van Rossum AC, Kamp O. Ultrasound enhanced prehospital thrombolysis using microbubbles infusion in patients with acute ST elevation
myocardial infarction: pilot of the Sonolysis Study. Ultrasound Med Biol 2012;38:247-52. 156. Morais NV, Tusutsui JM, Oliveira CP, Uchida AH, Oliveira SF, Lerario AC, Sbano JC, Ramires JA, Porter
TR, Mathias W Jr. Glycemic improvements normalizes myocardial microvascular reserve in type 2 diabetes. Int J Cardiol 2012;156:245-7.
157. Porter TR, Xie F. Can transcranial ultrasound and microbubble therapy ever enter the mainstream in acute stroke therapy? Expert Rev Cardiovasc Ther. 2012;10:549-51.
158. Gaibazzi N, Reverberi C, Lorenzoni V, Molinaro S, Porter TR. Prognostic value of high-dose dipyridamole stress myocardial contrast perfusion echocardiography. Circulation 2012;126:1217-24.
159. Dowsley TF, Bayne DB, Langnas AN, Dumitru I, Windle JR, Porter TR, Raichlin E. Diastolic dysfunction in patients with end-stage liver disease is associated with development of heart failure early after liver transplantation. Transplantation 2012;94:646-51.
160. Thomas D, Smith LM, O’Leary E, Smith K, Olson J, Nalty K, Hess R, Graham M, Therrien S, Porter TR. Prospective randomized comparison of conventional stress echocardiography and real time perfusion stress echocardiography in detecting significant coronary artery disease. J Am Soc Echocardiogr 2012;25:1207-14.
161. Kutty S, Wu J, Hammel JM, Xie F, Gao S, Drvol LK, Lof J, Radio SJ, Therrien SL, Danford DA, Porter TR. Microbubble mediated thrombus dissolution with diagnostic ultrasound for the treatment of chronic venous thrombi. PLos One 2012;7(12)e51453
162. Mattoso AAA, Kowatsch I, Tsutsui JM, de la Cruz VY, Ribeiro HB, Sbano JCN, Ramires JAF, Filho RK, Porter TR, Mathias Jr. W. Prognostic value of qualitative and quantitative vasodilator stress myocardial perfusion echochardiography in patients with known or suspected coronary artery disease. J Am Soc Echocardiogr 2013; 26(5):539-547
163. Lunning MA, Kutty S, Rome ET, Li L, Padiyath A, Loberiza F, Bociek RG, Bierman PJ, Vose JM, Armitage JO, Porter TR. Cardiac Magnetic Resonance Imaging for the Assessment of the Myocardium After Doxorubicin-based Chemotherapy. Am. J. Clin. Oncol. 2013 online
164. Porter TR, Smith LM, Wu J, Thomas D, Hass JT, Mathers DH, Williams E, Olson J, Nalty K, Hess R, Therrien S, Xie F. Patient Outcome Following 2 Different Stress Imaging Approaches: A Prospective Randomized Comparison. J Amer Coll Cardiol 2013;61(24)2446-2455.
165. Xie F, Gao S, Wu J, Lof J, Radio SJ, Vignon F, Shi W, Powers J, Unger E, Everbach EC, Liu J, Porter TR. Diagnostic Ultrasound Induced Inertial Cavitation to Non-invasively Restore Coronary and Microvascular Flow in Acute Myocardial Infarction Plos One 2013 ;8(7): e69780
166. Vignon F, Shi WT, Powers JE, Everbach EC, Liu J, Gao S, Xie F, Porter TR. Microbubble cavitation imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2013 Apr;60(4):661-70
167. Wu J, Xie F, Kumar T, Liu J, Lof J, Shi W, Everbach E C, Porter TR. Improved Sonothrombolysis from a Modified Diagnostic Transducer Delivering Impulses Containing a Longer Pulse Duration. Ultrasound Med Biol. 2014 Jul;40(7);1545-53 doi 10.1016/j.Ultramedbio.2014.01.015Epub2014Mar7
168. Shillcutt SK, Montzingo CR, Agrawal A, Khaleel M, Therrien SL, Thomas WR, Porter TR, Brakke TR. Echocardiography-Based Hemodynamic Management of Left Ventricular Diastolic Dysfunction: A Feasibility and Safety Study. Echocardiography.2014Mar.doi:1111/echo.12574
169. Kutty S, Wu J, Hammel JM, Abraham JR, Venkataraman J, Abdullah I, Danford DA, Radio SJ, Lof J, Porter TR. Prevention of Arterioveneous Shunt Occlusion Using Microbubble and Ultrasound Mediated Thromboprophylaxis. JAHA 2014 Feb 11;3(1)
170. Gao S, Zhang Y, Wu J, Shi WT, Lof J, Vignon F, Drvol L, Xie F, Muirhead D, Powers J, High R, White M, Porter TR. Improvements in Cerebral Blood Flow and Recanalization Rates with Transcranial Diagnostic Ultrasound and Intravenous Microbubbles Following Acute Cerebral Emboli. Invest Radiol 2014 Sept;40(9):593-600
171. Unger E, Porter TR, Lindner J, Grayburn P. Cardiovascular drug delivery with ultrasound and Microbubbles. Adv. Drug Delivery Rev. 2014 in press
172. Porter TR, Abdelmoneim S, Belcik JT, McCulloch ML, Mulvagh SL, Olson JJ, Porcelli C, Tsutsui JM, Wei K. Guidelines for the cardiac sonographer in the performance of contrast echocardiography: a focused update from the American Society of Echocardiography. J Am Soc of Echocardiography 2014
Aug;27(8):797-810; 173. Kutty S, Li L, Danford D, Houle H, Datta S, Mancina J, Xiao Y, Pedrizzetti, Porter TR. Effects of
Right Ventricular Hemodynamic Burden on Intraventricular Flow in Tetralogy of Fallot: An Echocardiographic Contrast Particle Imaging Velocimetry Study. J Am Soc of Echocardiology 2014 in press
174. Gaibazzi N, Pigazzani F, Reverberi C, Porter TR. Rest global longitudinal 2D strain to detect coronary artery disease in patients undergoing stress echocardiography: a comparison with wall-motion and coronary flow reserve responses. Echo Research and Practice 2014 in press
175. Steuter J, Bociek R, Loberiza F, Mathers D, Armitage J, Vose J, Bast M, Saxena S, Porter TR, Bierman, P. Utility of Pre-chemotherapy Evaluation of Left Ventricular Function for Patients With Lymphoma. Clinical Lymphoma, Myeloma & Leukemia 2015,p 29-34 in press
176. Ammi A, Lindner J, Zhao YA, Porter TR, Siegel R, Kaul S. Efficacy and Spatial Distribution of Ultrasound-Mediated Clot Lysis in the Absence of Thrombolytics, Thrombosis and Haemostais 2015– in press
177. Porter TR, Xie F. Contrast Echocardiography: Latest Developments and Clinical Utility. Current Cardiology Reports, 2015, Mar,17(3):569
178. Laiq Z, Smith LM, Xie F, Chamsi-Pasha M, Porter TR. Differences in patient outcomes after conventional versus real time perfusion stress echocardiography in men versus women: A prospective randomised trial. Heart 2015, Jan 21. Pii: heartjnl2014
B. ARTICLES ACCEPTED FOR PUBLICATION IN SCHOLARLY JOURNALS:
C. BOOKS PUBLISHED: NONE D. CHAPTERS IN BOOKS: 1. Porter TR, Mohanty, PK. Case 20: Evaluation of primary pulmonary hypertension. Atlas of Intravascular
Ultrasound; Raven Press, New York.1993. 2. Porter TR, Mohanty, PK. Case 22: Pharmacologic evaluation of pulmonary hypertension. Atlas of
Intravascular Ultrasound; Raven Press, New York.1993. 3. Porter TR, Mohanty, PK. Case 22: Pharmacologic evaluation for heart transplantation. Atlas of
Intravascular Ultrasound; Raven Press, New York.1993. 4. Porter TR, Xie F. Myocardial Contrast Echocardiography: Methods, analysis and applications. In: Otto CM, editor. Clinical Echocardiography, W.B. Saunders, 1997. p.95-112. 5. Porter TR. Transient response imaging during contrast echocardiography. In: Nanda NC, Schlief R,
Goldberg BB, editors. Advances in Echo Imaging Using Contrast Enhancement, 2nd Edition, Kluwer Academic Publishers, 1997. p.451-464
6. Porter TR. Transient response imaging. In: Bogdahn U, Becker G, Schllachetzki F, editors. Echoenhancers and Transcranial Color Duplex Sonography. Germany. Blackwell Wissenschafts-Verlag GmbH, 1998. p.192-203.
7. Brayman AA, Dalecki D, Wible Jr JH, Wu J, Abramowicz J, Meltzer RS, Porter TR, Shung K, Chang PP. Non-thermal bioeffects in the presence of gas-carrier ultrasound contrast agents. American Institute of Ultrasound in Medicine. (Submitted.)
8. Porter TR. PESDA (Perfluoro-exposed sonicated dextrose albumin). Textbook of Contrast Media. (Submitted)
9. Porter TR, Cwajg J. Contrast Echocardiography. In: Imaging in Cardiovascular Disease. Imaging in Cardiovascular Disease. G. Pohost, R O’Rourke, D Berman, P Shah, editors. Lippincott Williams & Wilkins, Philadelphia, PA. 2000. p.85-96.
10. Porter TR, Xie F. Ultrasound Contrast Agents to Detect Myocardial Perfusion During Stress Echocardiography. Golberg BB, Raichlen JS, Forsberg F, editors. Ultrasound Contrast Agents: Basic
Principles and Clinical Practice, 2nd Edition, Martin Dunitz Publishers, London, England. 2001. p.189-196.
11. Porter TR, Xie F. Accelerated Intermittent Harmonic Imaging. Golberg BB, Raichlen JS, Forsberg F, editors. Ultrasound Contrast Agents: Basic Principles and Clinical Practice, 2nd Edition, Martin Dunitz Publishers, London, England. 2001. p.67-70.
12. Porter TR, Xie F. Targeted Drug Delivery Using Intravenous Microbubbles. Golberg BB, Raichlen JS, Forsberg F, editors. Ultrasound Contrast Agents: Basic Principles and Clinical Practice, 2nd Edition, Martin Dunitz Publishers, London, England. 2001. p.347-352.
13. Porter TR, Noll D, Xie F. Myocardial Contrast Echocardiogrpahy: Methods, Analysis and Applications. Otto CM, editor. Textbook of Clinical Echocardiography, 2nd Edition, WB Saunders Company, Orlando FL. 2001.
14. Porter TR. Transient response imaging. In: Bogdahn U, Becker G, Schllachetzki F, editors. Echoenhancers and Transcranial Color Duplex Sonography. Germany. Blackwell Wissenschafts-Verlag GmbH, 1998. p.192-203.
15. Porter TR, Venneri L, Xie F. Myocardial Contrast Stress Echocardiography. Eugenio Picano, editor. Stress Echocardiography, 4th Edition, Springer-Verlag, Berlin, 2003. p. 311-328.
16. PORTER TR, Xie F. Microbubble Delivery Systems for Antisense Oligonucleotides. Vossoughi J, Kipshidze N, Moses, JW, Karanian JW, editors. Angiogenesis, Bench to Bedside, 1st Edition, Medical and Engineering Publishers, Inc, Washington, DC, 2003, p. 395-402.
17. Tsutsui JM, Grayburn PA, Xie F, Porter TR. Drug and gene delivery and enhancement of thrombolysis using ultrasound and microbubbles, ,Guest Editors Mani A. Vannan, Anthony N. De Maria: Cardiology Clinics: Contrast Echocardiology Philadelphia:W.B. Saunders Co;.
2004. p.299-312. 18. Porter TR, Xie F. Contrast Ultrasound Imaging: Methods, Analysis, and Applications. Otto CM, editor.
The Practice of Clinical Echocardiography, 3rd Edition 2006. 19. Porter TR, Xie F, Adelman SJ, Kipshidze N. Nanoparticle-based targeted delivery of therapeutics and
non-invasive imaging of unstable endothelium 2007. 20. Porter TR, Xie F. The practice of clinical echocardiography. 3rd edition. Elsevier; 2007. Chapter 3,
Contrast ultrasound imaging; methods, analysis and applications. 21. Porter TR. Echocardiography Self-assessment Program Version 6.6 Vol 6. American College of
Cardiology; 2010 Chapter 10 Case studies of echo contrast 22. Porter TR, Williams EM, Xie F. Echocardiography self-assessment program version 6.6 Vol6. American
College of Cardiology; 2010 Chapter 10, Echo Contrast Case 1 and 3. 23. Porter TR, Xie F. The practice of clinical echocardiography. 4. Elsevier; 2011. Chapter 3, Contrast
ultrasound imaging; methods, analysis and applications. 24. Porter TR, Xie F. Dynamic Echocardiography. 1 Vol. St Louis, MO: Elsevier; 2011 Chapter 51,
Diagnosis of coronary artery disease by dobutamine real-time myocardial contrast perfusion imaging; p.226-230
25. Olson J, Xie F, Porter TR. Advanced Approaches in Echocardiography. Practical Echocardiography Series. Editor: Catherine M. Otto, MD. Elsevier; 2012. Chapter 9, “Contrast Perfusion Echocardiography”
26. Olson J, Rogers K, Xie F, Porter TR. Chapter 5, “Tissue Harmonic Imaging” in Dynamic Echocardiography, 2e Editor: Roberto Lang, MD. Elsevier Saunders 2014.
27. Olson J, Xie F, Porter TR. Chapter 22, “Ultrasonic contrast agents” in Dynamic Echocardiography, 2e Editor: Roberto Lang, MD. Elsevier Saunders 2014.
28. Xie F, Olson J, Porter TR. Chapter 62, “Contrast-Enhanced Stress Echo” in Dynamic Echocardiography, 2e Editor: Roberto Lang, MD. Elsevier Saunders 2014.
29. Porter TR, Olson J, Xie F. Chapter 9, “Contrast-Enhanced Ultrasound Imaging” Clinical Echocardiography Review: A self-assessment tool, 2e. Editor: Drs. Allan Klein and Craig Asher. Wolters Kluwer Health 2015
E. ABSTRACTS AND PRELIMINARY COMMUNICATIONS (2005 TO PRESENT)
1. Hagen D, Xie F, Elhendy A, Porter TR. “Detection of Significant Coronary Artery Disease in Young, Otherwise Asymptomatic, Diabetic Patients with Real Time Perfusion Echocardiography During Dobutamine Stress” J Am Soc Echocardiogr 2006;19:660
2. Xie F, Lof J, He A, Thomas T, Matsunaga T, Unger E, Porter TR. “Recanalization of Occluded Arteriovenous Grafts with Diagnostic Ultrasound and Intravenous Microbubbles.” J Am Soc Echocardiogr 2006;19:603
3. Xie F, Lof J, Thomas T, Unger E, Matsunaga T, Porter TR. “Recanalization of Acute Coronary Thromboses with Diagnostic Ultrasound and Intravenous Microbubbles.” J Am Soc Echocardiogr 2006;19:642.
4. Dodla S, Xie F, O’Leary E, Porter TR. “Feasibility of Myocardial Perfusion and Wall Motion Analysis With Real Time Perfusion Echocardiography During Treadmill Exercise Stress.” J Am Coll Cardiol 2007
5. Xie F, Tsutsui JM, Anderson D, Radio SJ, Lof J, Porter TR. “Detection of Microbubble Adherence To Aortic Endothelium Early In The Atherosclerotic Process.” J Am Coll Cardiol 2007.
6. Xie F, O’Leary E, Dodla S, Porter TR. “Safety and Efficacy of Intermediate Dobutamine Stress Imaging With Real Time Perfusion Echocardiography in the Elderly.” J Am Coll Cardiol 2007.
7. Xie F, Everbach C, Matsunaga T, Lof J, He A, Bennett RM, Porter TR. “Detection of Intravascular Cavitational Activity during Treatment of Deep Vessel Thromboses with Diagnostic Ultrasound and Intravenous Microbubbles.” J Am Soc Echocardiogr 2007.
8. Xie F, Lof J, Matsunaga T, He A, Bennett RM, Dodla S, Porter TR. “Programmed Ultrasound Radiation Force in the Treatment in Acute Coronary Thromboses with Intravenous Microbubbles.” J Am Soc Echocardiogr 2007
9. Olson J, Karmazin K, Xie F, Porter TR. “Visualization of Cerebral Circulation with Transtemporal Real Time Perfusion Imaging During Dobutamine Stress Testing.” J Am Soc Echocardiogr 2007.
10. Dodla S, Xie F, Cory B, Stevens RB, O’Leary E, Porter TR. “Prognostic Value and Angiographic Correlation of Dobutamine Stress Imaging with Real Time Perfusion Echocardiography in Asymptomatic Diabetic Patients Undergoing Pre-Operative Evaluation.” J Am Soc Echocardiogr 2007.
11. Xie F, Lof J, Dodla S, Shevchuck S, Gilmore S, Matsunaga T, Zutshi R, Porter TR. “Intravenous Microbubbles Combined with Brief High MI DUS Impulses Guided by CPS Increase the Recanalization Rate of Acutely Thrombosed CA.” J Am Coll Cardiol 2008.
12. Dolan MS, Dodla S, Xie F, Cloutier D, Porter TR, Labovitz AJ. “Safety and Efficacy of Commercially Available Ultrasound Contrast Agents in Clinical Settings.” J Am Coll Cardiol 2008.
13. Dodla S, Xie F, O’Leary E, Smith M, Porter TR. “Comparison of Wall Motion and Perfusion in Detecting Coronary Artery Disease During Treadmill Exercise and Pharmacological Stress Imaging with Real Time Myocardial Perfusion Echocardiography” J Am Soc Echocardiogr 2008.
14. Koneru J, Dodla S, Xie F, O’Leary E, Porter TR. “Detection of Significant Left Anterior Descending Coronary Artery Disease in Pacemaker Dependent Patients Utilizing Real Time Perfusion Imaging During Dobutamine Stress Echocardiography.” Circulation 2008.
15. Xie F, Lof J, Dodla S, Zutshi R, Porter TR. “Rapid Resolution of ST Segment Elevation and Recovery and Function in Acute Myocardial Infarction with Low Dose Intravenous Thrombolytics, Transthoracic Ultrasound, and Intravenous Microbubbles.” Circulation 2008.
16. Dodla S, Xie F, O’Leary E, Smith M, Porter TR. “Detection of CAD Real Time Perfusion Imaging Versus Conventional Harmonic Imaging During Exercise and Dobutamine Stress Echocardiography.” Circulation 2008.
17. Xie F, Berger J, Porter TR. Utility of examining myocardial contrast enhancement during low dose dobutamine in predicting recovery of left ventricular function in chronic coronary artery disease. J Am Coll Cardiol 2009.
18. Xie F, Lof J, Matsunaga T, Zutshi R, Unger E, Porter TR. Transtemporal ultrasound-induced alterations in blood brain barrier permeability during an intravenous microbubble infusion. J Am Coll Cardiol. 2009.
19. Berger J, Xie F, Porter TR. Utility of examining capillary recruitment during low dose dobutamine to predict myocardial viability in chronic coronary artery disease. J Am Soc Echocardiogr. 2009.
20. Jahraus M, Xie F, Porter TR. Identification of recurrent disease within a revascularized coronary artery territory with real time perfusion stress imaging. J Am Soc Echocardiogr. 2009.
21. Xie F, Lof J, Unger E, Matsunaga T, Porter TR. Alterations in cerevral blood flow from a transtemporal ultrasound probe dotter effect: detection with transcranial real time perfuision imaging. J Am Soc Echocardiogr. 2009
22. Xie F, Lof J, Unger E, Matsunaga T, Porter TR. Enhanced Coronary Thrombolysis by three-dimensional transthoracic ultrasound and intravenous non-targeted microbubbles. Circulation. 2009.
23. Xie F, Lof J, Everbach EC, Fry G, Stolze EA, Rafter PG, Porter TR. The effects of attenuation and thrombus age on the success of ultrasound and mircobubble mediated thrombolysis. Circulation. 2009.
24. Porter TR, Slikkerveer J, Gao S, Unger E, Matsunaga T, Lof J, Xie F. Reduction in ultriamte infarct size despite persistent epicardial occlusion using three dimensional transthoracic ultrasound and intravenous non-targeted microbubbles. J Am Coll Cardiol. 2010.
25. Kutty S, Danford C, Fletcher SE, Erickson CC, Danford DA, Kugler JD, Olson J, Porter TR. Safety and efficacy of intravenous ultrasound contrast in evaluating surgically corrected congenital heart disease patients with difficult windows. J Am Coll Cardiol. 2010.
26. Akram K, Dodla S, Smith L, Olson J, Xie F, Porter TR. Six year predictive value of real time perfusion imaging during dobutamine stress echocardiography. J Am Coll Cardiol. 2010.
27. Porter, TR, Xie F, Adolphson M, O’Leary E, Olson J, Erdkamp M, Therrien SL, Wong BF, Eifert-Rain S, Abdelmoneim SS, Mulvagh S. Detection of coronary artery disease with regadonson stress real-time perfusion echocardiography. Circulation 2010.
28. Xie F, Gao S, Drvol LK, Unger E, Morehead S, Kerschen A, Lof J, Porter TR. Effects of combined platelet and fibrin targeted microbubbles on the success of ultrasound and microbubble mediated thrombus dissolution of older thrombi. Circulation 2010.
29. Porter TR, Xie F, Adolphson M, O’Leary E, Olson J, Erdkamp M, Therrien S, Wong BF, Eifert-Rain S, Abdelmoneim SS, Mulvagh S. The optimal timing for detection of perfusion and wall motion abnormalities with real time perfusion echocardiography following regadenoson bolus injection. Circulation 2010.
30. Porter TR, Lof J, Gao S, Kutty S, Xie F. Effect of underlying coronary atherosclerosis on the effectiveness of three dimensional guided high mechanical index and intravenous microbubbles in treating acute coronary thromboses. Circulation 2010.
31. Porter TR, Thomas D, Therrien SL, Gao S, O’Leary E, Xie F. The clinical profile of patients with a high ischemic threshold indentified during real time perfusion stress echocardiography. J Am Coll Cardiol. 2011.
32. Porter TR, Thomas D, Therrien SL, Gao S, O’Leary E, Xie F. Mechanism for improved detection of coronary artery disease with real-time myocardial contrast echocardiography: prospective randomized comparison with conventional stress echocardiography. J Am Coll Cardiol 2011.
33. Porter TR, Gao S, Shi W, Francois V, Powers J, Lof J, Kutty S, Xie F. Utilization of diagnostic transtemporal guided high mechanical index ultrasound and a systemic microbubble infusion to treat ischemic stroke without fibrinolytic agents. J Am Coll Cardiol 2011.
34. Kutty S, Houle H, Olson J, Therrien SL, Erickson CC, Pedrizzetti G, Danford DA, Porter TR. Effects of right ventricular hemodynamic burden and geometry on right and left ventricular vorticity fields in Tetralogy of Fallot: A high resolution echo contrast particle imaging velocimetry study. J Am Soc Echocardiogr. 2011
35. Liu J. Gao S, Porter TR, Everbach EC, Shi W, Vignon F, Powers J, Lof J, Turner J, Xie F. Transcranial threshold of inertial cavitation induced by diagnostic ultrasound and microbubbles. 11th International Syposium on Therapeutic Ultrasound. April 2011
36. Gao S, Liu J, Porter TR, Wu J, Lof J, Tranquart F, Yan F, Powers J, Xie F. Effects of microbubbles of different size distribution and shell compostion on diagnostic ultrasound-induced thrombus dissolution. J Am Soc Echocardiogr. 2011
37. Mattoso AA, Kowatsch I, Tsutsui JM, Yezinia de La Cruz V, Ribeiro HB, Porter TR, Mathias W. Long term prognostic value of quantitative dobutamine stress real time myocardial perfusion echocardiography in patients with suspected coronary artery disease and normal left ventricular function. J Am Soc Echocardiogr. 2011
38. Kutty S, Gao S, Xie F, Drvol L, Therrien SL, Danford DA, Lof J, Hammel JM, Porter TR. Microbubble enhanced sonothrobolytic therapy facilitates reduction of central venous catheter associated thrombi in vivo. Circulation 2011.
39. Wu J, Gao S, Weeks K, Sricharoen N, Therrien SL, Xie F, Porter TR. Correlation of real time myocardial perfusion imaging during dobutamine stress echocardiography with fractional flow reserve (FFR) assessments. Circulation 2011.
40. Liu J, Gao S, Xie F, Lof J, Shi WT, Vignon F, Powers JE, Porter TR. Efficacy and safety of transcranial ultrasound and microbubbles in treating acute ischemic stroke without thrombolytic agents. Circulation 2011.
41. Wu J, Liu J, Kumar T, Liu J, Kutty S, Lof J, Xie F, Porter TR. Correlation of inertial cavitation threshold with thrombolysis efficacy when utilizing diagnostic ultrasound guided high mechanical index impulses and microbubbles. J Am Coll Cardio 2012;59:e1131
42. Xie F, Gao S, Wu J, Unger E, Liu J, Shi WT, Vignon F, Powers J, Lof J, Kutty S, Liu J, Porter TR. Prospective randomized comparison of long versus short pulse duration therapeutic impulses in improving epicardial and microvascular recanalization during a continuous microbubble infusion in acute myocardial infarction. J Am Coll Cardio 2012;59:e1132
43. Wu J, Therrien SL, Mukherjee S, Porter TR. Effects of non-alcoholic steatohepatitis on coronary artery disease detection during dobutamine stress real time perfusion stress echocardiography. J Am Coll Cardio 2012;59:e1279
44. Porter TR, Smith L, Xie F, Smith K, Olson J, Nalty K, Hess R, Graham M, Therrien S. The negative predictive value of real time perfusion stress echocardiography versus conventional stress echocardiography in predicting patient outcome. J Am Soc Echocardiogr 2012
45. Kumar T, Liu J, Wu J, Xie F, Lof J, Kutty S, Porter TR. Improved sonothrombolysis utilizing a low mechanical index therapeutic ultrasound impulse containing a longer pulse duration. J Am Soc Echocardiogr 2012
46. Ammi AY, Zhao Y, Lindner JR, Porter TR, Siegel RJ, Xie A, Kaul S. Optimal Frequency and Acoustic Pressure for Sonothrombolysis with Microbubbles in a Flow System: Clinical Implications. Circulation 2012
47. Sarji R, Therrien SL, High R, Miles C, Porter TR. Dobutamine Stress Real Time Perfusion Echocardiography Identifies Significant Coronary Artery Disease and Predicts Outcome in Patients With End Stage Renal Disease Undergoing Transplant Evaluation. Circulation 2012
48. White M, Zhang Y, Perkins T, Powers J, Shi WT, Vignon F, Xie F, Lof J, Wu J, Liu J, Porter TR. Quantitative Improvements in Cerebral Blood Flow Detected with Magnetic Resonance Imaging Following Transtemporal Ultrasound and Microbubbles in Pigs with Acute Stroke. Circulation 2012
49. Wu J, Xie F, Liu J, Lof J, Drvol L, Kutty S, Porter TR. Detection of increased targeted H2S delivery to the myocardial microvasculature using ultrasound and intravenous microbubbles. Circulation 2012
50. Xie F, Wu J, Sayyed S, Liu J, Powers J, Shi W, Vignon F, Lof J, Kutty S, Porter TR. Effects of guided high mechanical index impulses and intravenous microbubbles on infarct size and systolic
function assessed by cardiac magnetic resonance imaging following acute myocardial infarction. Circulation 2012.
51. Porter TR. The Future of Sonothrobolysis.18th European Symposium on Ultrasound Contrast Imaging 17-18 January 2013, Rotterdam, The Netherlands
52. Porter TR. Microbubbles and Drug/Gene Delivery. American Institute of Ultrasound in Medicine April 2013
53. Porter TR, Wu J, Xie F, Therrien S, Lorenzoni V, Molinaro S, Reverberi C, Gaibazzi N. Multicenter Evaluation of the Prognostic Value of Real Time Myocardial Perfusion Imaging during Dipyridamole versus Dobutamine Stress Echocardiography. American College of Cardiology 2013
54. Porter TR, Wu J, Xie F, Therrien S, Lorenzoni V, Molinaro S, Reverberi C, Gaibazzi N. Incremental Prognostic Value of Myocardial Perfusion Stress-Echocardiology in Patients with known Coronary Artery Disease. American College of Cardiology 2013
55. Wu J, Xie F, Lof J, Stoze E, Fry G, Drvol L, Porter TR. Improvement in Microvascular Outcome Using Both Image Guided Therapeutic Ultrasound Impulses with a Long Pulse Duration and High Mechanical Index During An Intraveneous Microbubble Infusion in Acute Myocardial Infarction. Am Soc Echocardiogr 2013
56. Porter TR, Lorenzoni V, Wu J, Xie F, and Gaibazzi N. The Obesity Paradox And predicting Obese Patient Outcome with Real Time Myocardial Contrast Stress Echocardiography. Am Soc Echocardiogr 2013
57. Wu J, Xie F, O’Leary E, Steuter J, and Porter TR. Comparison of Fractional Flow Reserve Assessment with Stress Myocardial Contrast Echocardiography in Angiographically Significant Coronary Stenoses. Am Soc Echocardiogr 2013
58. Xie F, Wu J, Lof J, Vignon F, Mills D, Shi WT, Powers J, Porter TR. Optimizing the Mechanical Index and Pulse Duration for Transthoracic Ultrasound Induced Microvascular Thrombolysis in Acute Myocardial Infarction. American Heart Association 2013
59. Pacella J, Chen X, Brands J, Schnatz F, Porter TR, Villanueva F. Microbubble-Mediated Sonothrombolysis with Long Tone Burst Ultrasound for the Treatment of Microvascular Microembolization: An in vivo Study. American Heart Association 2013
60. Zhang Y, Wu J, Shi WT, Lof J, Vignon F, Drvol L, Xie F, Talmon G, Muirhead D, Powers J, White ML, Porter TR. Quantitative Improvements in Cerebral Blood Flow Using Transtemporal Ultrasound and Mircrobubbles in Acute Ischemic Stroke Model with Multiple Cerebral Emboli. American Heart Association 2013
61. Laiq Z, Smith LM, Porter TR. Gender Difference in the Predictive Value of Stress Echocardigraphy, With and Without Perfusion Imaging, In Predicting Outcome. American Heart Association 2013
62. Kutty S, Wu J, Hammel JM, Abraham JR, Venkataraman J, Abdulla I, Lof, Radio SJ, Porter TR. Microbubble And Ultrasound Mediated Thromboprophylaxis in Porcine Models of Extracardiac shunts. American Heart Association 2013
63. Porter TR. Basis for Ultrasound Parameters used for Initial Clinical Trials in Ultrasound Thrombolysis. Session title Therapeutic Ultrasound Part II. International Contrast Ultrasound Society meeting “Bubble Conference” October 2013 Chicago, IL
64. Porter TR. Diastolic Function and Beyond: Clinical Application of Echo Diastolic Meaurements - Proper use of the Data. American Society of Echocardiography’s 24th Annual Echo Hawaii.
65. Porter TR. TEE and Interventional Symposium: Assessment of Prosthetic Valves. American Society of Echocardiography’s 24th Annual Echo Hawaii.
66. Porter TR. Ischemic Heart Disease: Contrast for Myocardial Perfusion: How and Why? American Society of Echocardiography’s 24th Annual Echo Hawaii.
67. Porter TR. Latest Clinical Trials and Implications for CEUS. Contrast-enhanced Ultrasound Curriculum Development meeting. Coral Gables, FL February 2014
68. Porter TR. CEUS Use in Special Patient Populations. Contrast-enhanced Ultrasound Curriculum Development meeting Coral Gables, FL February 2014
69. Xie F, Wu J, Lof J, Sayyed S, Porter TR. High Mechanical Index Impulses from a Diagnostic Transducer During an Intravenous Microbubble Infusion Can Reduce Ultimate Infarct Size When Compared to Full Dose Tissue Plasminogen Activator in Acute ST Segment Elevation Myocardial Infarction. American College of Cardiology 2014
70. Wu J, Xie F, O'Leary E, Steuter J, Porter TR. Relationship Between Quantitative Severity of Coronary Stenosis, Fractional Flow Reserve Findings, and Demand Stress Myocardial Perfusion Findings in Patient with Symptomatic Coronary Artery Disease. American College of Cardiology 2014
71. Porter TR. Safety of Ultrasound Contrast Agents in Patients with Intracardiac Shunts. Am. Society of Echocardiography 2014
72. Porter TR, Adams M, Desjardins G, Glas K, Olson J, Shillcutt S, Troughton R. Guidelines for the Use of Echocardiography as a Monitor Therapeutic Intervention in Adults: A report from the American Society of Echocardiography. Am Society of Echocardiography 2014
73. Wu J, Barton D, Xie F, O’Leary E, Steuter J, Pavlides G, Porter TR. Comparison of Fractional Flow Reserve Assessment with Stress Myocardial Contrast Echocardiography in Angiographically Significant Coronary Stenoses. Jrnl of American College of Cardiology 2014
74. Baibhav B; Chamsi-Pasha M; Xie F; Porter T. Importance of Stress Perfusion and Diastolic Function in Predicting Outcome of Contemporary End Stage Liver Disease Patients Undergoing Transplantation. American College of Cardiology; 2014
75. Mulvagh S; Xie F; O'leary E; Adolphoson M; Abdelmoneim S; Omer M; Kirby M; Rain S; Hagen M; Olson J; Nalty K; Porter TR. Coronary Artery Disease is Rapidly Detected by Regadenoson Stress Contrast Echocardiography Using Optison or Definity. Am Soc of Echocardiogr; 2014
76. Kutty S; Xiao Y; Wu J; Lof J; Xie F; Porter TR. Utilization of ultrasound induced microbubble destruction to treat catheter induced vasospasm. Am Soc of Echocardiogr; 2014
77. Xie F; Lof J; Everbach EC; Vignon F; Shi WT; Powers J; Porter TR. Ultrasound Induced Inertial Cavitation Improves Microvascular Blood Flow to a Greater Degree than Stable Cavitation Following Thrombotic Occlusion. American Heart Association; 2014
78. Gaibazzi N; Lorenzoni V; Reverberi C; Wu J; Xie F; Porter TR. Effect of Stress Perfusion and Wall Motion Responses on Outcome of Obese versus Non-obese Subjects Without Known Coronary Artery Disease Referred For Stress Testing : the âObesity Paradoxâ Stratified by Clinical and Stress Imaging Variables. Second International Symposium in Ultrasound Molecular Imaging; Chongqing, China. 2014 Apr
79. Porter TR, Xie F, Lof J. Effect of Nitric Oxide Inhibition on Skeletal Muscle Microvascular Flow in Acute Peripheral Artery Thromboembolism Treated with High Mechanical Pulses and Systemic Microbubbles. American College of Cardiology, 64th Annual Scientific Session, March 2015
F. PUBLISHED CONTINUING EDUCATION MATERIALS: NONE PUBLISHED COMPUTER SOFTWARE NONE TEACHING ACTIVITIES:
A. TEAM TAUGHT COURSES
B. COURSES COORDINATED /SUPERVISED
C. COURSES TAUGHT
D. GRADUATE STUDENT/POSTDOCTORAL TEACHING:
E. FELLOWSHIP/RESIDENCY TRAINING: Jan 2014 Imaging Conf CT Post Processing/Radiation Reduction Techniques Feb 2014 Imaging Conf Prosthetic Valve Evaluation Apr 2014 Imaging Conf Infective Endocarditis and Cardiac Mass Evaluation Jun 2014 Imaging Conf 2014 AHA/ACC Valvular Heart Disease Guidelines Sept 2014 Imaging Conf Intro to CT of the Heart/Applications Grand Rounds Cardiology Research Series Imaging Conf Aortic Stenosis Dec 2014 Imaging Conf Aortic Regurgitation Grand Rounds Myocardial viability studies-the evidence for Clinical Impact Jan 2015 Imaging Conf Prosthetic Valve Evaluation Mar 2015 Imaging Conf Acute Aortic Syndrome Grand Rounds Abstract presentation
F. CONTINUING MEDICAL EDUCATION COURSES: Attending Physician:
Omaha Veteran’s Administration ICU 2/93, 10/93, 10/94 (students, residents) Omaha Veteran’s Administration 1997-2013
Echocardiography Attending:
University of Nebraska Medical Center 7/92-present (fellows) Omaha Veteran’s Administration 7/92-3/94, 7/94-7/96 (fellows) Omaha Veteran’s Administration 1997-present Stress Echo/TEE 7/96-present
Cardiology Consult:
University of Nebraska Medical Center 12/92-present Ad Hoc Peer-Reviewer: Circulation Journal of the American College of Cardiology American Journal of Cardiology American Heart Journal Journal of the American Society of Echocardiography (2002-2004) Journal of Ultrasound in Medicine European Journal of Echocardiography Molecular Therapy Society for Vascular Surgery JACC Cardiovascular Imaging Cardiac Ultrasound TODAY
Updated 3/2/15