multiple pregnancy2.pptx

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    MULTIPLE PREGNANCY Hari Dev

    2008 MBBS

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    MULTIPLE PREGNANCY

    • Presence of more than one fetus inthe gravid uterus

    • 1% of all pregnancies• Hellin’s Rule

    – Twins : 1 in 80

    – Triplets : 1 in 80 × 80 – Quadruplets : 1 in 80 × 80 × 80….

    • Ge ell!l!"# : tud! of twins

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    • $YG%SITY " #efers to the T!pe of$onception.

    " onl! determined ! &'(

    testing

    • CH%RI%NICITY " T!pe of Placentation " prenatall! ! ultrasound " postnatall! ! e)amining

    mem ranes.

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    &' $YG%SITY

    &i*!gotic+ono*!gotic Twins

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    &'DI$YG%TIC T(INS)BIN%*ULAR

    +,-

    ,ertilisation of - ova ! di erent spermato*oa.

    /ach twin has its own placenta chorion amnion.

    ence alwa!s dichorionic diamniotic .

    ,actors a ecting " ethnic group " increasing maternal age " increasing parit! " ,amil! histor! of twinning " ovulation induction with clomiphene

    citrate2 gonadotrophins resulting in multiple ovulation.

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    DI$YG%TIC T(INS)BIN%*ULAR

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    2'M%N%$YG%TIC ) BIN%*ULAR)IDENTICAL

    2,- #esult from splitting of a single fertili*ed ovum

    (lwa!s same se) and loo3 ali3e. 4 5&/'T5$(6 7

    #ate of mono*!gotic twinning is relativel! constant not a ected ! an! factors.

    True etiolog! un3nown.

    T!pe of placentation is determined ! the time ofsplitting

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    M%N%$YG%TICT(INS

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    M%N%$YG%TIC ) BIN%*ULAR)IDENTICAL

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    2'CH%RI%NICITY

    • T!pe of Placentation

    • Postnatall!" /)amination of+em ranes

    • Prenatall!" ! 9ltrasound

    • 5deal time for assesment is efore 1

    wee3s

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    (.i/. is !re

    i !r1an1 3#"!si1#!r /.!ri!ni/i1#44

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    CH%RI%NICITY ………;h!

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    CH%RI%NICITY ………;h!

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    Ul1ras!un5 De1er ina1i!n !6C.!ri!ni/i1#

    • Nu 7er !6 sa/s . 4 efore 10 wee3s 7 - sacs = dichorionic ingle sac " monochorionic

    • Pla/en1a

    • Se

    • In1er19in e 7rane thic3er and more echogenic in dichorionic

    .

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    • Twin pea3 2 6am da sign " characteristic of dichorionic

    pregnancies " chorionic tissue etween - la!ers

    of intertwin mem rane at theplacental origin

    • T ign = in monochorionic nochorionic tissue

    • 5f no mem rane is seen in etween =

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    Ul1ras!un5 5i:eren1ia1i!n !6

    /.!ri!ni/i1# Cri1eri!n M!n!/.!ri!ni/ Di/.!ri!ni/

    Placenta ingle &ou le

    ,etal e) -------- &iscordance+em rane ?- mm @- mm

    'o: of la!ers inmem rane

    - la!ers la!ers

    Twin pea3 sign ( sent Present

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    Ma1ernal C! li/a1i!ns

    Antepartum Intrapartum1.Hyperemesis 1.Dysfunctional labour

    2.Hydramnios 2.Malpresentation

    3.Pre-eclampsia 3.Operative delivery

    .Pressure symptoms .Postpartum!emorr!a"e

    #.$naemia #.%etained Placenta

    &.$ntepartum!emorr!a"e

    &.Premature separationof placenta

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    Ma1ernal C! li/a1i!ns ;An1e ar1u

    H# ere esisH# ere esis

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    1. Pre a1uri1#

    • ingle most important cause ofperinatal mortalit! and mor idit!.

    • /nsure deliver! in a tertiar! carecentre.>>

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    2' IUGR$an a ect one or oth fetuses.

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    B. 5'D6/ ,/T(6 &/+5 /&eath of one twin

    NEUR%L%GICAL

    DAMAGEin survivin"

    T(IN

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    B. 5'D6/ ,/T(6 &/+5 /M!n!/.!ri!ni/

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    >'M!n!/.!ri!ni/ M!n!a ni!1i/19innin"

    een in less than 1% of all twin pregnancies

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    C. T9in 19in Trans6usi!n S#n5r! e? TTS@

    Fccurs in monochorionicplacentation due to (G anastomoseswith resultant How in one direction.

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    C. T9in 19in Trans6usi!n S#n5r! e? TTS@

    $an e acute or chronic

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    Ul1ras!un5 in TTS STUCT(IN SIGN

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    • +anagement after deliver! = E /.an"e 1rans6usi!n

    • $hronic TT = Serial a ni! re5u/1i!n =" #educes preterm la our " #educe h!drostatic pressure = " improves circulation and urine production.

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    • (cute TT can occur in B rd trimesteror in la our = sudden death of onetwin

    • Fverall mortalit! is I0%

    • igh incidence of $P andneurological a normalities insurvivors.

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    I. C!n"eni1al An! aliesT#9$T9#(6 +(6,F#+(T5F'

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    'uchal Translucenc!

    Mi5Tri es1er

    A ni!/en1esis is 1.e "!l5s1an5ar5

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    Mana"e en1 !6An! alies

    DICH%RI%NIC PREGNANCY

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    (nomalies 9niKue to twins..

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    C!n !ine5 T9insAl9a#s !n!3#"!1i/

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    T F#($FP(D9 5 $ 5FP(D9$#('5FP(D9

    #($ LP(D9PLFP(D9F+P (6FP(D9

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    A/ar5ia/

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    MECHANISMPUMP T(IN ACARDIAC

    T(IN

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    T9in Reverse5 Ar1erialPer6usi!n Se uen/e

    ? TRAP 7•Pump twin = high output cardiac failureh!drops pol! h!dramnios and death•Fverall perinatal mortalit! of pump twin is C0%

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    PUMPT(IN

    ACARDIACT(IN

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