morbid obesity and surgical management
TRANSCRIPT
Dr Gaurav Gupta ,JNM Raipur
MORBID OBESITY AND SURGICAL MANAGEMENT
.
Dr Gaurav GuptaRSO dept. of surgeryJNM medical college raipur
Dr Gaurav Gupta ,JNM Raipur
WHAT IS MORBID OBESITY
• Multi factorial diseaes of excess fat storage.• Lifelong & progressive
• 100 LB ABOVE IDEAL BODY WEIGHT• TWICE IDEAL BODY WEIGHT• OR A BMI>40 KG/M2• BMI > 35 WITH COMORBID CONDITIONS
Gaurav Gupta
Dr Gaurav Gupta ,JNM Raipur
HOW IS IT CALCULATED
Dr Gaurav Gupta ,JNM Raipur
27.5
Dr Gaurav Gupta ,JNM Raipur
HOW DOES MORBID OBESITY DIFFER FROM BEING OVERWEIGHT OR OBESE??Overweight and obese – reversible
medical management
Morbid obesity - surgical intervention
Dr Gaurav Gupta ,JNM Raipur
OBESITY-PATHOPHYSIOLOGY• Complex interaction– genetic , – Behavioral – environmental factors.
• Specific genes--FTO(fat mass and obesity related) --MC4R(melanocortin 4 receptors) --Thrifty genes • Second leading cause of preventable
death ,exceeded only by cigarette smoking.
Dr Gaurav Gupta ,JNM Raipur
.
Dr Gaurav Gupta ,JNM Raipur
CONDITIONS ASSOCIATED WITH MORBID OBESITY
.
TYPE2 DIABETES
CARDIOVASCULAR HYPERTENSION,CAD,CHF HYPERTRIGLYCERIDEMIA VASCULAR DS.MENTAL HEALTH LOW SELF ESTEEM DEPRESSIONORTHOPEDIC OSTEOARTHRITIS degenerative joints
.
HEPATIC CHOLELITHIASIS,CIRRHOSIS STEATOHEPATITIS RENAL MICROALBUMINURIANEUROLOGICAL PSEUDOTUMOR CEREBRISKIN ACANTHOSIS NIGRICANS
INTERTRIGO
Dr Gaurav Gupta ,JNM Raipur.
• REPRODUCTIVE• FEMALE- PCOD HYPERANDROGENISM EARLIER MENARCHE DYSMENORRHEA
• MALE- LATE PUBERTY PSEUDO MICROPENIS REDUCED ANDROGENS
• SLEEP APNEA• BREAST,UTREINE,PROSTRATE ,COLON CANCER
• Most frequent problem– arthritis & degenerative joints
Dr Gaurav Gupta ,JNM Raipur
RISK ASSOCIATED WITH MORBID OBESITY
• It is an extreme health hazard with medical ,psychological social,physical, & economic co-morbidities.
Increased risk of developing Hypertension DM type 2, heart disease stroke gallstone disease CA breast, prostate,colon
Dr Gaurav Gupta ,JNM Raipur
Dr Gaurav Gupta ,JNM Raipur
TREATMENT• Diet• Exercise• Behavior therapy• MEDICAL MANAGEMENT Phentermine is an appetite suppressant
Orlistat blocks absorption of fats in the GIT • These medications cause modest weight loss at best
and often lead to weight regain when stopped.
Dr Gaurav Gupta ,JNM Raipur
INDICATIONS FOR BARIATRIC SURGERY Patients must meet the following criteria
• B MI >40 kg/m2 or BMI >35 kg/m2 with an associated medical comorbidity.
• Failed dietary therapy
• Psychiatrically stable without alcohol dependence or illegal drug use
• AGE-16 TO 65 years
Dr Gaurav Gupta ,JNM Raipur
.• Knowledgeable about the operation and its sequelae
• Motivated individual
• Medical problems not precluding probable survival from surgery
Dr Gaurav Gupta ,JNM Raipur
CONTRAINDICATIONS TO BARIATRIC SURGERY
• Cardiac problem• Respiratory dysfunction• Significant psychological disorders• Who are unable to ambulate• Prader-Willi syndrome
Dr Gaurav Gupta ,JNM Raipur
PERIOPERATIVE EVALUATION• LABORATORY EVALUATION: Blood count, TFT. Serum & urine cortisol, lipid
profile, vitamin (A, B1, B6, B12, C).Serum Insulin, C-Peptide.
• UPPER ENDOSCOPY: Rule out gastric pathology, search and treat H
pylori infection.
• ULTRASOUND OF THE ABDOMEN: Cholelithiasis cholecystectomy
Dr Gaurav Gupta ,JNM Raipur.
• CARDIOVASCULAR/RESPIRATORY EVALUATION:Exclude any contraindications to anesthesia by TMT, Echo, PFT, ABG , CXR etc.
•PSYCHIATRIC EVALUATION:.
• ENDOCRINE EVALUATION:
• DENTAL EVALUATION
Dr Gaurav Gupta ,JNM Raipur
LAPARASCOPIC PROCEDUREDONE UNDER G.A 5 TO 6 PORTS
THE BENEFITS ARE:
•Less Pain•Quicker recovery•Fewer complications(PTE)•Less scar•Shorter hospital stay
Dr Gaurav Gupta ,JNM Raipur
.
EXTRA LONG TROCARS
OPTI-VIEW TROCARS
GASTRIC CALIBRATION TUBE
Dr Gaurav Gupta ,JNM Raipur
.
Dr Gaurav Gupta ,JNM Raipur
TYPES OF BARIATRIC SURGERY• RESTRICTIVE VERTICAL BANDED GASTROPLASTY (VBG) ADJUSTABLE GASTRIC BANDING (AGB) SLEEVE GASTRECTOMY (LSG) GASTRIC PLICATION GASTRIC BALOON
• Largely Restrictive, mildly malabsorbtive Roux-en-Y gastric bypass • PREDOMINANTLY MALABSORBTIVE BILIOPANCREATIC DIVERSION (BPD) DUODENAL SWITCH (DS)
Dr Gaurav Gupta ,JNM Raipur
RESTRICTIVE PROCEDURES
Creats a small gastric pouch & a degree of outlet obstruction leading to delayed gastric emptying.
Goal is to reduce oral intake,produce early satiety & leave alimentary canal in continuity,minimising risks of metabolic complications.
Dr Gaurav Gupta ,JNM Raipur
VERTICAL BANDED GASTROPLASTY The stomach is partitioned
along its axis with a non-
adjustable poly-urethane
band and with linear&
circular staples to create a
small upper stomach pouch
with a restrictive orifice to
the rest of the stomach
Dr Gaurav Gupta ,JNM Raipur
Dr Gaurav Gupta ,JNM Raipur
. ABANDONED BECAUSE OF
• POOR LONG-TERM WEIGHT LOSS, • HIGH RATE OF LATE STENOSIS OF THE GASTRIC
OUTLET, AND • TENDENCY FOR PATIENTS TO ADOPT A HIGH-
CALORIE LIQUID DIET, THEREBY LEADING TO REGAIN OF WEIGHT.
Dr Gaurav Gupta ,JNM Raipur
LAPAROSCOPIC ADJUSTABLE GASTRIC BANDING
TYPES OF BANDS• LAP-BAND (INAMED Health,Santa Barbara,
Calif )• Realize band (Ethicon Endo-Surgery,
Cincinnati, Ohio). • The Swedish Adjustable Gastric BAND• MIDBAND• the Heliogast band
Dr Gaurav Gupta ,JNM Raipur
.AN INFLATABLE SILICONE BAND IS
PLACED AROUND THE TOP PORTION OF THE STOMACH, TO FORM A SMALL STOMACH POUCH
BAND IS CONNECTED TO A TUBE THAT LEADS TO A PORT BELOW THE SKIN (FILL – PORT).
FOLLOW UP: INJECT OR REMOVE SALINE TO MAKE BAND TIGHTER OR LOOSER
INFLATABLE SILICONE BAND
Dr Gaurav Gupta ,JNM Raipur
REALIZE BAND
Dr Gaurav Gupta ,JNM Raipur
Dr Gaurav Gupta ,JNM Raipur.
THIS BAND IN THE STOMACH INDUCES WEIGHT-LOSS IN 3 WAYS:
1.SMALL STOMACH POUCH SENSATION OF FULLNESS
2. SQUEEZING OF THE STOMACH POUCH LIKE AN HOUR GLASS PROLONGS THE SENSATION OF FULLNESS
3. SUPPRESSES APPETITE BY CENTRAL ACTION
Dr Gaurav Gupta ,JNM Raipur
COMPLICATIONS OF BANDING.
• Slippage(food
intolerance and GER)• Perforation of Stomach• Mal positioning• Abdominal Pain• Heartburn• Vomiting
• Failure to Lose Weight• Gastric Erosion• Dilated Esophagus• Infection of System• Fatigue or malfunction• Inability to Adjust the
Band
Dr Gaurav Gupta ,JNM Raipur
LAPARASCOPIC SLEEVE GASTRECTOMY• standard procedure
• Stomach is reduced to about 25% of its original size
• A bougie 32 - 40 Fr is used in the procedure
Dr Gaurav Gupta ,JNM Raipur
ADVANTAGES -SLEEVE GASTRECTOMY
• Simple ,rapid & less traumaticsafe in high risk patient
• Good resolution of co-morbidities and good weight loss
• Preservation of pylorus(no dumping)
• Reduction in internal hernias ,malabsorbtion(seen with RYGB)
• Ability to modify the gastric sleeve later to a lap.RYGB or lap.DS in a 2nd stage.
Dr Gaurav Gupta ,JNM Raipur
COMPLICATION
• Leakage along the long gastric staple line.• Long term fistula formation.
Dr Gaurav Gupta ,JNM Raipur
.Sleeve gastrectomy induces weight loss by:
• 1.MECHANICAL RESTRICTION by reducing the volume of the stomach and impairing stomach mobility. Also called ‘Food limiting’ operation.
• 2.HORMONAL MODIFICATION by removing a great part of the Ghrelin (Hunger Hormone) production tissue.
Dr Gaurav Gupta ,JNM Raipur
Postoperative period
• No nasogastric tube • Gastrograffin study:• UGIE – to check leakage• From D2 to D14,liquid diet. • next 3 weeks soft diet• Normal diet after 1 month
Dr Gaurav Gupta ,JNM Raipur
INTRAGASTRIC BALOON
• Endoscopically balloon left for max. 6 months
• Average weight loss of 5–9 BMI IN 6months
• Stepdown procedure prior to another bariatric surgery
Soft silicon balloon
Dr Gaurav Gupta ,JNM Raipur
ENDO BARRIER LINER SYSTEM
Endoscopically inserting a flexible tube-like barrier into the duodenum & prox. Jejunum
Mimics the effects of gastric bypass surgery
Loose weight by delaying digestion
Has to be removed after 6 months
Dr Gaurav Gupta ,JNM Raipur
ROUX-EN-Y GASTRIC BYPASS (RYGB) LARGELY RESTRICTIVE, MILDLY MALABSORPTIVE Components• Small proximal gastric pouch(10 to 15ml)• Jejunum divided 30 to 40 cm distal to ligament of
Treitz• Roux limb at least 75 cm in length(if BMI in
40s=80to120cm, if BMI>50=150cm)
Dr Gaurav Gupta ,JNM Raipur
.
ROUX LIMB Y LIMB
Dr Gaurav Gupta ,JNM Raipur
Dr Gaurav Gupta ,JNM Raipur
ADVANTAGES OF ROUX-EN-Y BYPASS
• Most commonly performed.
• Most reliable for long term weight loss -avg 60 to 75 %.
• NO Malnutrition
• Improvement & resolution of:
Type 2 DM – 90% Sleep apnea -90% Hypertension-70% Hyperlipidaemia -70% Heartburn from GERD- all patients.
Dr Gaurav Gupta ,JNM Raipur
COMPLICATION ROUX-EN-Y BYPASS
• Irreversible.
• Stricture of gastrojejunostomy.-10% (long term)
• Dumping syndrome
• Long term risk of protein ,vitamin,iron deficiency, & marginal ulceration of GJA.
• Long term risk of intestinal obstruction – 2%.
Dr Gaurav Gupta ,JNM Raipur
LARGELY MALABSORPTIVE, MILDLY RESTRICTIVE
• BILIOPANCREATIC DIVERSION (BPD)• DUODENAL SWITCH (DS)
•Mechanism short gut syndrome and/or by accomplishing distal mixing of bile and pancreatic juice with ingested nutrients thereby reducing absorption
•Purely malabsorptive operations- not recommended due to serious nutritional deficiencies
Dr Gaurav Gupta ,JNM Raipur
BILIOPANCREATIC DIVERSION (BPD)
• Wt loss- malabsorption>> restrictive• Distal hemigastrectomy(250ml for BMI<50 & 150ml
for BMI >50)• Effective ileum length – 250 cm• Distal common chennal- 50 cm(for abs. fat &
protein).
Dr Gaurav Gupta ,JNM Raipur
BILIOPANCREATIC DIVERSION (BPD)
250 cm
50cm
Dr Gaurav Gupta ,JNM Raipur
After BPD• 2 -5 daily bowel movement.• Excessive flatulence and foul smelling stools
• Mc long term complication protein malnutrition the common channel may need to be lengthened with a reoperation(4% cases).
• Ability to absorb simple sugars,alcohol,& short chain TG is good i.e. Patient must avoid overeating of sweets ,milk product,soft drinks,alcohol,fruits.
Dr Gaurav Gupta ,JNM Raipur
BILIOPANCREATIC DIVERSION WITH DUODENAL SWITCH
• Entire length of alimentary length -250 cm• Common channel- 100 cm• Goal- produce a lesser curvature gastric sleeve
with a volume of 150-200 ml.• Duodenum is divided 2cm beyond the pylorus
Dr Gaurav Gupta ,JNM Raipur
.
RED---FOOD
GREEN—BILIOPANCREATIC SERETIONS
BILIOPANCREATIC DIVERSION WITH DUODENAL SWITCH
100 cm(distal common channel)
Entire length of alimentary length -250 cm
Dr Gaurav Gupta ,JNM Raipur
Dr Gaurav Gupta ,JNM Raipur
COMPLICATIONS• Peri-operative:
Bleeding
Injury to Liver or Spleen.
• Early Post-operative Complications (30 days):
Bleeding
anastomosis leak
Infection
Strictures
Deep venous thrombosis
Pulmonary complication -Atelectatsis, pneumonia, pulmonary embolism,
respiratory arrest secondary to sleep apnea, and acute respiratory distress
syndrome (ARDS).
.
Dr Gaurav Gupta ,JNM Raipur
.Gastrointestinal (GI) complication - Ulcer, stricture, anastomonic
obstruction, and small bowel obstruction
• Late Complications (greater then 30 days):
GI ulcer (stricture, obstruction),
Nutrition deficiency (protein, vitamin or mineral)
Internal/ incisional hernia,
Failure of weight loss or regain of lost weight
Psychological Side effects –Depression, disruption of social
relationships
Dr Gaurav Gupta ,JNM Raipur.
Dr Gaurav Gupta ,JNM Raipur
CONCLUSION• Bariatric surgery is an effective
means to achieve clinically significant, permanent weight loss with low rates of complications.
Dr Gaurav Gupta ,JNM Raipur
Dr Gaurav Gupta ,JNM Raipur
.