module catalogue · 2019-11-20 · basics of scanning electron microscopy ... 53 lab principles of...

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Module Catalogue

Biophysics M.Sc.

Ulm University

Faculty of Natural Sciences

Ulm, 20 Nov. 19

Content Programme Description ............................................................................................. 5

Degree Programme Objectives .............................................................................................. 5

Curriculum ................................................................................................................................ 5

Module Descriptions .................................................................................................. 7

Compulsory Biophysics Modules .......................................................................................... 7 Biophysics Laboratory Course ................................................................................................. 7 Biophysics Seminar ................................................................................................................. 9 Biophysics: Fundamental Methods........................................................................................ 11 Biophysics: Advanced Methods ............................................................................................. 13

Specialisation Modules ......................................................................................................... 15

Biology Department .............................................................................................................. 15

Protein Biochemistry ............................................................................................................ 15 Advanced Protein Biochemistry ............................................................................................. 15 Practical Skills in Protein Biochemistry ................................................................................. 17

Cell Biology and Genetics .................................................................................................... 19 Methods in Genetics .............................................................................................................. 19 Practical Skills in Genetics .................................................................................................... 21

Ecology ................................................................................................................................. 23 Evolutionary Ecology for Biophysics...................................................................................... 23 Marine Ecology ...................................................................................................................... 25 Soil and Water ....................................................................................................................... 27

Microbiology ......................................................................................................................... 29 Advanced Microbiology in Biophysics ................................................................................... 29 Microbiology in Biophysics .................................................................................................... 31

Neurobiology ........................................................................................................................ 33 Methods in Neurobiology ....................................................................................................... 33 Practical Skills in Neurobiology ............................................................................................. 35

Biomaterials.......................................................................................................................... 37 Biosensors and Biochips ....................................................................................................... 37 Polymers in Medicine ............................................................................................................ 39

Physics Department ............................................................................................................. 41

Physics ................................................................................................................................. 41 Biophotonics .......................................................................................................................... 41 NMR Spectroscopy and Imaging Methods ............................................................................ 43 Gene Expression ................................................................................................................... 45 Molecular Motors ................................................................................................................... 47 Cellular Biophysics ................................................................................................................ 49 Biophysics of Hearing and Seeing......................................................................................... 51 Basics of Scanning Electron Microscopy .............................................................................. 53 Lab Principles of Transmission Electron Microscopy ............................................................ 55 Principles of Transmission Electron Microscopy and Seminar ............................................. 57

Chemistry Department ......................................................................................................... 59

Organic Chemistry ............................................................................................................... 59 Biopolymers ........................................................................................................................... 59 Biological Chemistry .............................................................................................................. 61 Project Work in Macromolecular Chemistry .......................................................................... 63

Anorganic Chemistry ............................................................................................................ 65 Analytical Spectroscopy ........................................................................................................ 65 Inorganic Materials Synthesis/Inorganic Nanomaterials ....................................................... 67 Special Topics in Analytical Chemistry IV ............................................................................. 69 Special Topics in Analytical Chemistry V .............................................................................. 71

Stochastics and Bioinformatics ............................................................................................ 73 Evolutionäre Algorithmen ...................................................................................................... 73 Bioinformatics and System Biology ....................................................................................... 75

Praktische Algorithmen der Bioinformatik und Computerlinguistik mit Lisp .......................... 77 Learning Systems I ................................................................................................................ 79 Learning Systems II ............................................................................................................... 81 Neurotechnology: Brain-Machine-Interfacing ........................................................................ 83 Einführung in die Neuroinformatik ......................................................................................... 85

Adaptation Modules ............................................................................................................... 87

Biochemistry, Chemistry or Molecular Biology ..................................................................... 87 Introductory Chemistry .......................................................................................................... 87 Practical Skills in Molecular Biology ...................................................................................... 89 Biology and Cell Biology ........................................................................................................ 91

Physics and Mathematics .................................................................................................... 93 Mathematical Methods for Material Science ......................................................................... 93 Practical Skills in Physics ...................................................................................................... 95

Additive Key Qualifications .................................................................................................. 97 Additive Key Qualifications .................................................................................................... 97

Research Phase ..................................................................................................................... 99 Biophysics Research Project ................................................................................................. 99 Selected Research Project .................................................................................................. 101 Master’s Thesis.................................................................................................................... 103

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Programme Description

Degree Programme Objectives The aim of this Master programme is to prepare students for the interdisciplinary nature of modern-day Life Sciences. Research in the field of Life Sciences is growing increasingly in dimension and relevance. Graduates from both colleges and universities look forward more and more to the quantitative handling of experimental data, as well as to the application and development of modern measurement techniques, which is possible only in an interdisciplinary study programme.

In particular, students enrolling in the two-year Master's programme:

will deepen their previous knowledge of biophysics, chemistry and biochemistry, molecular medicine and biology

will gain the interdisciplinary academic skills necessary for scientific and technical work, i.e. in industry, commerce or the public service

will learn to work autonomously and to solve independently complex scientific and engineering problems by means of their advanced technical knowledge

will be trained in quantitative thinking and in modern experimental techqniques and instrumentation

will be prepared for a doctoral programme

Curriculum The course consists of an initial period of teaching followed by an extended research period including the master’s thesis. Each student has to take several fundamental biophysics modules in preparation of the Biophysics Research Project. Additionally some specialised modules have to be selected in preparation of a second research project (Selected Research Project). These modules are designed to provide key knowledge and skills enabling the student to carry out research at the academic level and the final thesis.

Semester

Curriculum/Study Plan

1 Compulsory Biophysics

Modules

30 CP

Biophysics Lab 8 CP

Biophysics Seminar 4 CP

Biophysics: Fundamentals 9 CP

Biophysics: Advanced 9 CP

Specialisation Modules

18 CP

Adaptation Modules

9 CP

German Language

Course or ASQ

3 CP

2 Subject I

6 or 12 CP

Subject II

6 or 12 CP

3 Biophysics Research Project

15 CP

Selected Research Project

15 CP

4 Master’s Thesis

30 CP

Compulsory Biophysics Modules (30 CP)

Compulsory modules focusing on Biophysics:

Biophysics Laboratory Course (8 CP ungraded)

Biophysics Seminar (4 CP graded)

Biophysics: Fundamental Methods (9 CP graded)

Biophysics: Advanced Methods (9 CP graded) Specialisation Modules (18 CP)

Modules have to be chosen from two of the listed specialisation subjects:

Biochemistry

Cell Biology and Genetics

Inorganic Chemistry

Microbiology

Neurobiology

Organic Chemistry

Biomaterials

Physics

Stochastics and Bioinformatics

More Specialization areas are in principle allowed as Analytical Chemistry or Translational Neuroscience. This would need to be discussed and approved by the Biophysics Study and Examination Commission. In each subject at least 6 CP are necessary, grades count towards the final grade. The modules should be chosen according to the Selected Research Project. They might be a prerequisite.

Adaptation Modules (9 CP):

Courses at the Bachelor level from a different field than the one where the Bachelor degree was

obtained:

for physicists: Biochemistry, Biology, Organic Chemistry or Molecular Medicine

for all others: Physics and Mathematics

The 9 CP are graded but they do not count towards the final grade. ASQ (Additive Key Qualifications) (3 CP)

All non-native speakers have to attend a German language course during the first semester. German students can chose to attend courses from ASQ (Additive Schlüsselqualifikationen) offered by the Humboldt-Studienzentrum für Philosophie und Geisteswissenschaften and the Zentrum für Sprachen und Philologie.

Research Phase

The last year of the master programme is dedicated to the research phase consisting of three

modules:

Selected Research Project (15 CP): a research project, which can be carried out in a

non-biophysics laboratory.

Biophysics Research Project (15 CP): a research project, which has to be carried out in

a biophysics laboratory.

Master’s Thesis (30 CP)

https://www.uni-ulm.de/en/einrichtungen/humboldt.html

https://www.uni-ulm.de/en/einrichtungen/sprachenzentrum.html

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Module Descriptions

Compulsory Biophysics Modules

Module Biophysics Laboratory Course

Code 72378

Instruction language German or English

ECTS credits 8

Credit hours 8

Duration 1 semester

Cycle Each semester

Coordinator Prof. Othmar Marti

Lecturer Prof. Othmar Marti, Dr. Manuel Gonçalves

Allocation to study programmes

Biophysics M.Sc., compulsory module, 1st semester

Formal prerequisites None

Recommended prerequisites

None

Learning objectives Students who successfully passed this module

understand modern measurement techniques and are able to use complex measuring equipments

have the ability to make measurements and analyse the data of advanced physical experiments

learn to work with a tidy and complete recording of measurement data

are able to set-up, run and evaluate complex experiments as well as to report the results in a clear manner

Syllabus Modern microscopics methods

Scattering and diffraction techniques

Optical Spectroscopy

Biophysics and Soft Matter Physics

Literature Lab manual

Teaching and learning methods

Lab work with 4 two-day experiments (8 hours per week)

PHYS3800.0 Advanced Physics Laboratory Course

Workload 120 hours laboratory course (attendance time)

120 hours self-study, data evaluation, report writing

Total: 240 hours

Assessment Succesful participation in four experiments and written reports. Each lab report has to be assessed as satisfactory by the supervisor.

Examination 13509 Biophysics Laboratory Course

Grading procedure This module is not graded.

Basis for Experimental Research Project

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Module Biophysics Seminar

Code 72379


ECTS credits 4

Credit hours 2

Duration 1 semester

Cycle Each semester

Coordinator Prof. Jens Michaelis

Lecturer Prof. Christof Gebhardt, Prof. Kay Gottschalk, Prof. Jens Michaelis


Biophysics M.Sc., compulsory module, 1st or 2nd semester



None


are able to read and understand from a scientific point of view a physical topic in the library, databases and journals (information competence)

have the ability to structure scientific content and present it in a talk within a given time

learn to defend their point of view in a scientific discussion

Syllabus Elaboration (content structure) and presentation of a scientific talk. In each semester will be given the possibility to choose between many advanced seminars on specialized topics in theoretical and experimental physics.

Literature Depending on the theme of the each seminar


Seminar (2 hours per week)

Workload 30 hours exercise (attendance time)

90 hours talk preparation

Total: 120 hours

Assessment The talk elaboration and presentation as well as the relative scientific discussion will be evaluated.

Examination 13510 Biophysics Seminar

Grading procedure The note is the result of the evaluation of the talk and discussion.

Basis for

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Module Biophysics: Fundamental Methods

Code 72380

Instruction language English

ECTS credits 9

Credit hours 9

Duration 1 semester

Cycle Each winter semester


Lecturer Prof. Christof Gebhardt, Prof. Kay E. Gottschalk, Prof. Jens Michaelis


Biochemistry M.Sc., elective module, 1st semester

Biophysics M.Sc., compulsory module, 1st semester



Molecular Physics, Condensed Matter Physics


understand the basic terms and concepts of Biophysics

are able to describe biophysical phenomena with simple physical models

Syllabus Time and length scales in Biophysics

Brownian motion and diffusion, chemotaxis of bacteria

Physics at low Reynold’s numbers

Structure and mechanics of cellular biomolecules, methods of structure determination

Polymer models for the description of biomolecules

Protein folding

Force spectroscopy

Fluorescence spectroscopy and microscopy

Electrostatics in Biophysics

Neurobiology

Lab course:

Gene expression

Bioinformatics

Protein Labelling

Protein crystallization

Literature Phillips, Kondev, Theriot: Physical Biology of the Cell, Garland Science

Howard: Mechanism of Motor Proteins and the Cytoskeleton, Sinaur and Associates

Lakowicsz: Principles of Fluorescence Spectroscopy, Springer US


Lecture (4 hours per week) with exercise (1 hour per week)

For non-physicists: PHYS5117.2 Fundamental Methods in Biophysics for Biochemists + PHYS5117.0 Fundamental Methods in Biophysics

For physicists: PHYS5117.1 Fundamental Methods in Biophysics for Physicists + PHYS5117.0 Fundamental Methods in Biophysics

3 Labs, PHYS5148.0

Workload 60 hours lecture (attendance time)

15 hours exercises (attendance time)

10 hours laboratory class (attendance time)

30 hours of report writing and data analysis of lab class

150 hours self-study and exam preparation

Total: 270 hours

Assessment Written or oral examination. A prerequisite for the participation in the examination is an ungraded course achievement. Form and scope of the examination and of the course achievement are determined and notified by the instructor at the beginning of the course.

Examination 13515 Biophysics: Fundamental Methods (precourse)

13511 Biophysics: Fundamental Methods

Grading procedure The module grade is the examination grade.

Basis for Modules Biophysics: Advanced Methods, Gene Expression, Molecular Motors, Cellular Biophysics

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Module Biophysics: Advanced Methods

Code 72381


ECTS credits 9

Credit hours 9

Duration 1 semester

Cycle Each summer semester


Lecturer Prof. Christof Gebhardt, Prof. Kay E. Gottschalk, Prof. Jens Michaelis


Biophysics M.Sc., compulsory module, 2nd Semester



Biophysics: Fundamental Methods

Learning objectives Students who passed this module

understand complex experimental setups in modern experimental Biophysics

can apply basic biophysical methods tocurrent issues in molecule and cell Biology

are able to describe biological phenomena with physical models of different complexity

Syllabus Advanced Biophysics Labs experiments to be assigned by the coordinator, from the list below.

Taking place in 1st Semester counting for 2nd :

Protein folding

Stopped-flow kinetics

Single-molecule fluorescence

Taking place in the 2nd semester:

Ion channels

Ligand binding

Fluorescence correlation spectroscopy (FCS)

Live Cell Imaging

Perception. Psycophysics of hearing and color vision

Fluorescence lifetime

Lipid monolayer

Kinetics of protein folding

Class work to be selected from one of the specialisation physics modules:

Gene expression or Molecular Motors or Cellular Biophysics

Literature


One lecture (1 x 2 hours per week)

Practical course (5 hours per week)

Workload 30 hours lectures (attendance time)

75 hours practical course (attendance time)

30 hours practical course (report writing and data analysis)


Total: 270 hours


Examination 13516 Biophysics: Advanced Methods (precourse)

13512 Biophysics: Advanced Methods


Basis for Biophysics Research Project

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Specialisation Modules Modules from two different subjects have to be chosen, and at least 6 credit points are necessary for each subject. The modules should be chosen according to the Selected Research Project. They might be a prerequisite.

Biology Department

Protein Biochemistry

Module Advanced Protein Biochemistry

Code 74013


ECTS credits 6

Credit hours 4

Duration 1 semester


Coordinator Prof. Marcus Fändrich

Lecturer Prof. Marcus Fändrich


Biophysics M.Sc., elective module, 2nd semester



Courses in Biology at the Bachelor level, e.g. from Adaptation Modules.


have a broad overview on all current aspects of protein biochemistry

have insight in the most important protein-folding diseases

have gained experienced in giving a scientific talk

Syllabus Functional chemistry of amino acids, protein modifications, crosslink, further description of the secondary structure, solubility, stability and aggregation, protein-folding in vitro and in cells, protein-folding diseases, therapeutic and industrial proteins, protein design, protein biotechnology, expression, purification

Biochemistry, pathology and therapy of protein-folding diseases like Alzheimer's disease, Parkinson's disease, BSE, scrapie, Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, AA amyloidosis etc.

Literature Will be announced in the courses


Protein Biochemistry, lecture, 2 credit hours, 3 credit points

Protein-Folding Diseases, seminar, 2 credit hour, 3 credit points

Workload Attendance: 60 hours

Private study: 120 hours

Sum: 180 hours

Assessment Written exam, graded.

Examination 14013 Protein Biochemistry

Grading procedure The grade of the module will be the grade of the exam.

Basis for Research project in Protein Biochemistry or Pharmaceutical Biotechnology

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Module Practical Skills in Protein Biochemistry

Code 74014


ECTS credits 6

Credit hours 6

Duration 1 semester


Coordinator Prof. Marcus Fändrich

Lecturer Prof. Marcus Fändrich





Courses in Biology at the Bachelor level, e.g. from Adaption Modules.


know the key biophysical techniques for investigation of proteins and protein structures

are experienced in planning scientific experiments themselves and have an idea of independent scientific working

Syllabus Protein expression and purification with column chromatography machines

Packing of chromatography columns

Protein quantification

Protein stability measurements

Electron microscopy

Visualization of protein structures

Infrared spectroscopy

Protein misfolding and amyloid fibrillation

Literature Will be announced in the courses


Protein Biochemistry (laboratory course), 6 credit hours, 6 credit points



Sum: 180 hours

Assessment Attested report, ungraded.

Examination 14014 Practical Skills in Protein Biochemistry


Basis for Master’s Thesis in Protein Biochemistry or Pharmaceutical Biotechnology

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Cell Biology and Genetics

Module Methods in Genetics

Code 74020


ECTS credits 6

Credit hours 4

Duration 1 semester

Cycle Summer semester

Coordinator Prof. Nils Johnsson

Lecturer Dr. Alexander Dünkler, Dr. Thomas Gronemeyer, Prof. Nils Johnsson





Courses in Biology at the Bachelor level, e.g. from Adaption Modules


have profound knowledge about the regulation of polarized growth and asymmetric cell division including the required theoretical background

are capable of self-sustained preparation of a subject based on scientific literature and oral presentation including discussion

Syllabus Theoretical background covering the topics intracellular protein transport, protein secretion, cell division and the regulation of these events

Oral presentation of the experimental results and preparation of a written report

Literature Molecular Biology of the Cell. Alberts et al. Wiley-VCH 2011.

Cell Biology. Pollard, Earnshaw. Spektrum 2008

Molecular Cell Biology. Lodish et al. Freeman 2008

Biochemistry. Voet & Voet Wiley VCH 2011


BIO.0027.003 Molecular Cell Biology (lecture), 1 credit hour, 1.5 credit points

BIO.0027.004 Molecular Cell Biology (seminar), 1 credit hour, 1.5 credit points

BIO.0027.002 Genetics (seminar), 2 credit hours, 3 credit points



Sum: 180 hours

Assessment Oral exam, graded.

Examination 14020 Methods in Genetics


Basis for Research project in Genetics

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Module Practical Skills in Genetics

Code 74021


ECTS credits 6

Credit hours 6

Duration 1 semester


Coordinator Prof. Nils Johnsson

Lecturer Dr. Alexander Dünkler, Dr. Thomas Gronemeyer, Prof. Nils Johnsson





None

Learning objectives Students, who successfully passed this module, have knowledge of the required laboratory techniques to answer subject specific questions on the basis of experiments.

Syllabus Hands-on application of genetic, cell biological and protein chemical techniques in the context of a current research project

Literature Molecular Biology of the Cell. Alberts et al. Wiley-VCH 2011.

Cell Biology. Pollard, Earnshaw. Spektrum 2008

Molecular Cell Biology. Lodish et al. Freeman 2008

Biochemistry. Voet & Voet Wiley VCH 2011


Laboratory Course Genetics, 6 hours/week



Sum: 180 hours

Assessment The grade of the module will be the grade of the oral exam. No prerequisites are necessary for exam registration.

Examination 14021 Practical Skills in Genetics


Basis for Research project in Genetics

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Ecology

Module Evolutionary Ecology for Biophysics

Code 75056


ECTS credits 3

Credit hours 2

Duration 1 semester


Coordinator Prof. Manfred Ayasse

Lecturer Prof. Manfred Ayasse



Formal prerequisites


Biodiversity and ecology

Learning objectives Students who have successfully completed this module:

have a good theoretical background about the principles and concepts involved in the interactions of organisms and their environment

understand the fundamental ecological, behavioural, chemical and genetic factors as well as population-health related processes that drive the adaptive evolution of intraspecific and interspecific relationships.

Syllabus The lectures cover major levels driving the interactions of organisms and their environment. Animal-plant / animal-animal interactions:

Basic knowledge about the various functions of chemical and visual signals and cues in animal-plant / animal-animal interactions: e.g. mutualistic interactions (pollination, floral signals for pollinator attraction, pollination syndromes, seed dispersal) and antagonistic interactions (herbivory and plant defensive substances) are introduced using various examples (ant-plant interactions, tritrophic interactions, deception and others).

Furthermore, applied aspects of animal-plant interactions are discussed, e.g. pollination of commercially used plants.

Animal-environment interactions:

Introduction of the effects of environmental changes such habit destruction, fragmentation or changes in the species composition on wildlife health and ecosystem functioning.

Theoretical background on both ecological and genetic methods for population health assessment will be provided.

Literature Agosta WC: Dialog der Düfte –Chemische Kommunikation. Spektrum Akademischer Verlag Heidelberg (1992).

Harborne JB: Ökologische Biochemie. Spektrum Verlag, neueste Auflage

Herrera CM, Pellmyr O: Plant – Animal interactions, Blackwell Publishing, Oxford (2002).

Johnson SD, Schiestl FP: Floral Mimicry (2016).

Proctor HC, Yeo P, Lack A: The natural history of pollination, Timber Press Inc., Portland (1996).

Further literature is presented in the course


Evolutionary Ecology: Interactions of Organisms and their Environment (V), 2SWS



Sum: 90 hours


Examination 15056 Evolutionary Ecology for Biophysics


Basis for Research project in Ecology

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Module Marine Ecology

Code 72228

Instruction language English/German

ECTS credits 3

Credit hours 2

Duration 1 semester

Cycle Winter semester

Coordinator Prof. Karl-Heinz Tomaschko

Lecturer Prof. Karl-Heinz Tomaschko





Learning objectives After successful completion this module, students:

possess the basic physical and chemical knowledge for understanding the anomalies of water and their meaning for the existence of life.

know the important impacts of climate, global air- and water movements and plate tectonics on marine habitats.

are familiar with the fundamentals of marine ecology, marine food webs, nutrient cycles and vertical zonings.

understand the ecology of various habitats in the sea as well as their coaction in the entire marine ecosystem.

Syllabus This module covers the following subject-specific topics:

Basic physics and chemistry of water

Climate

Plate tectonics

Water waves, streams and tides

Light

Zoning of marine habitats

Marine food webs

Anthropogenous factors

El Niño - Southern Oscillation

Rockbound coasts

Sand beaches

Seagrass meadows

Polar seas

Tropical seas and coral reefs

Predators and prey animals

Deep sea

Literature General references in the lecture

For the Mediterranean Sea:

Das Mittelmeer, Bd.1, Allgemeiner Teil: Fauna, Flora, Ökologie von Robert Hofrichter, Spektrum Akademischer Verlag

Das Mittelmeer, Bd.2/1, Bestimmungsführer: Fauna, Flora, Ökologie von Robert Hofrichter, Spektrum Akademischer Verlag


Marine Ecology [Marine Ökologie] (lecture), 2 h/week



Sum: 90 hours


Examination 12670 Marine Ecology


Basis for Research project in Ecology

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Module Soil and Water

Code 74394


ECTS credits 9

Credit hours 6

Duration Block course


Coordinator Prof. Dr. Marian Kazda

Lecturer Biology lecturers from following universities:

Ulm University (Ulm, Germany)

University of South Bohemia in Ceske Budejovice (Budweis, Czech Republic)

Aix-Marseille University (Marseille, France)

Estonian University of Life Sciences (Tartu, Estonia)





Learning objectives Students who have successfully completed this module:

have knowledge and competence regarding interactions between soils, plants and soil organisms with special emphasis on soil processes and effects of drought and flooding on plants and soil organisms.

know the major risks of soil degradation.

are familiar with the link between soil functions and societal needs and expectations.


Soil science

Ecology

Plant sciences

Zoology

Literature Lectures notes and practical course notes

Scientific articles for the seminars


Lectures, 2 h/week

Seminars, 1 h/week

Practical courses / excursions



Sum: 270 hours


Examination 12670 Marine Ecology


Basis for Research in Ecology/Biodiversity

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Microbiology

Module Advanced Microbiology in Biophysics

Code 73425


ECTS credits 12

Credit hours 11

Duration 1 semester


Coordinator Prof. Dr. Bernhard Eikmanns

Lecturer Prof. Dr. Peter Dürre, Prof. Dr. Bernhard Eikmanns





Courses in Biology at the Bachelor level, e.g. Molecular biology and Biochemistry


have extended knowledge on key topics in microbiology and molecular microbiology

have gained deeper insight into current research in molecular microbiology through recent original articles and have improved skills in presenting results of own research

have gathered experience in actively discussing scientific presentations

have gained skills and competences in independent research in the area of microbiology with respect to special methods and to a potential future Master thesis.

are able to individually work under supervision on own topics related to current research.


Lecture - Microbiology IV (Microbial Regulation):

RNA: Structure and function

Transcription and translation

Bacterial regulatory mechanisms at level of RNA and DNA (at level of proteins not included

Regulation of bacteriophage lambda

Seminar:

Presentation and critical discussion of state-of-the-art original research publications in the area of host-microbe interactions, pathogenicity and host defense

Laboratory course (Microbiology Advanced Course):

Principles and methods of enrichment, isolation and characterization of microorganisms (Lactic acid bacteria, Bifidobacteria, Chromobacteria, aerobic spore-formers, Pseudomonas); Ames-test for identification of carcinogenics; serological and enzymatic analysis of ß-galactosidase in Escherichia coli; isolation and analysis of genes from Acinetobacter sp. and cloning of these genes; cultivation of Ashbya gossypii and analysis of substrate consumption and riboflavine formation by a mutant of this fungus; characterization of a key enzyme of riboflavine synthesis; growth, substrate consumption and glutamate production of Corynebacterium glutamicum; analysis of key enzymes of glutamate synthesis

Organization of biosafety and health safety in laboratories; introduction to relevant laws and regulations (e.g., the German Biostoffverordnung and Gentechnikrecht); safety rules and preventive measures during work in laboratories (e.g.,operating instructions); safe working and risk assessment

Literature Madigan MT, Matinko JM Brock: Biology of Microorganisms, 13. Auflage . Pearson Education, Inc., Upper Saddle River, USA 2012.

Wagner R: Transcription Regulation in Procaryotes . Oxford University Press, Oxford, New York, USA 2000.

Lewin B: Molekularbiologie der Gene . Spektrum Akademischer Verlag Heidelberg Berlin 2002.

Antranikian G : Angewandte Mikrobiologie. Springer-Verlag Berlin Heidelberg New York 2006.

Cossart P, Boquet P, Normark S, Rappuoli R: Cellular Microbiology, 2. Auflage, ASM Press, USA 2004

Ofek I, Hasty Dl, Doyle RJ: Bacterial Adhesion to Animal Cells and Tissues, ASM Press, USA 2003

Janeway CA, Travers P, Walport M, Shlomchik M: Immunologie, 7. Auflage, Spektrum Akademischer Verlag Heidelberg Berlin 2009

Wilson M: Bacteriology of Humans – An Ecological Perspective, Blackwell Publishing USA 2008


Microbiology IV (Microbial Regulation) (lecture), 3 credit hours, 4 credit points, summer semester

Microbiology Advanced Course (laboratory course), 8 credit hours, 8 credit points, summer semester



Sum: 360 hours

Assessment Audited protocol, not graded; Successful participation at the seminar; not graded. Oral examination (30 min.) to Microbiology IV and Microbiology Advanced Course, marked

Examination 13620 Advanced Microbiology in Biophysics

13365 Laboratory Advanced Microbiology in Biophysics

Grading procedure The grade of the module will be the average of the individual exam grades weighted by the credit points of the individual exams.

Basis for Research project in Microbiology

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Module Microbiology in Biophysics

Code 73423


ECTS credits 6

Credit hours 6

Duration 1 semester

Cycle Summer/Winter semester

Coordinator Prof. Dr. Bernhardt Eikmanns

Lecturer Prof. Dr. Peter Dürre, Prof. Dr. Bernhardt Eikmanns





Courses in Biology at the Bachelor level, e.g. Molecular biology and Biochemistry


have extended knowledge on key topics in microbiology and molecular microbiology

have gained deeper insight into current research in molecular microbiology through recent original articles and have improved skills in presenting results of own research

Syllabus This module covers one or more of the following subject-specific topics:

Lecture - Microbiology IV (Microbial Regulation):

RNA: Structure and function

Transcription and translation

Bacterial regulatory mechanisms at level of RNA and DNA (at level of proteins not included

Regulation of bacteriophage lambda

Seminar:

Presentation and critical discussion of state-of-the-art original research publications in the area of host-microbe interactions, pathogenicity and host defense

Laboratory course (Microbiology Advanced Course):

Principles and methods of enrichment, isolation and characterization of microorganisms (Lactic acid bacteria, Bifidobacteria, Chromobacteria, aerobic spore-formers, Pseudomonas); Ames-test for identification of carcinogenics; serological and enzymatic analysis of ß-galactosidase in Escherichia coli; isolation and analysis of genes from Acinetobacter sp. and cloning of these genes; cultivation of Ashbya gossypii and analysis of substrate consumption and riboflavine formation by a mutant of this fungus; characterization of a

key enzyme of riboflavine synthesis; growth, substrate consumption and glutamate production of Corynebacterium glutamicum; analysis of key enzymes of glutamate synthesis

Organization of biosafety and health safety in laboratories; introduction to relevant laws and regulations (e.g., the German Biostoffverordnung and Gentechnikrecht); safety rules and preventive measures during work in laboratories (e.g.,operating instructions); safe working and risk assessment

Literature Madigan MT, Matinko JM Brock: Biology of Microorganisms, 13. Auflage . Pearson Education, Inc., Upper Saddle River, USA 2012.

Wagner R: Transcription Regulation in Procaryotes . Oxford University Press, Oxford, New York, USA 2000.

Lewin B: Molekularbiologie der Gene . Spektrum Akademischer Verlag Heidelberg Berlin 2002.

Antranikian G : Angewandte Mikrobiologie. Springer-Verlag Berlin Heidelberg New York 2006.

Cossart P, Boquet P, Normark S, Rappuoli R: Cellular Microbiology, 2. Auflage, ASM Press, USA 2004

Ofek I, Hasty Dl, Doyle RJ: Bacterial Adhesion to Animal Cells and Tissues, ASM Press, USA 2003

Janeway CA, Travers P, Walport M, Shlomchik M: Immunologie, 7. Auflage, Spektrum Akademischer Verlag Heidelberg Berlin 2009

Wilson M: Bacteriology of Humans – An Ecological Perspective, Blackwell Publishing USA 2008


Microbiology IV (Microbial Regulation) (lecture), 3 credit hours, 4 credit points, summer semester

Microbiology Lab Course, 2 credit hours, 2 credit points, summer semester



Sum: 180 hours


Examination 13620 Advanced Microbiology in Biophysics

13280 Laboratory Microbiology in Biophysics

13282 Microbiology in Biophysics


Basis for Research project in Microbiology

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Neurobiology

Module Methods in Neurobiology

Code 74018


ECTS credits 6

Credit hours 4

Duration 1 semester


Coordinator Prof. Günter Ehret

Lecturer Prof. Günter Ehret, Prof. Harald Wolf


Biophysics M.Sc., elective module, 3rd semester





have in-depth knowledge of o the energetics and allometry of animal movement. o basic biomechanical principles governing walking and flying. o basic orientation mechanisms in animal migration and

navigation. o the neural mechanisms of sensory and sensorimotor integration

and of motor control in invertebrates. o ion channel function and modulation of neuronal activity.

are able to give an oral presentation based on scientific literature.


Energetics and allometry of animal movement

basic biomechanics of walking and flight

basic principles of animal migration and navigation

mechanisms of sensory and sensorimotor integration and of motor control in arthropods

ion channels and their contribution to neuronal excitation.

Literature Dudel, Menzel, Schmidt: Neurowissenschaft, Springer-Verlag, Berlin.

Neuweiler G, Heldmaier G: Vergleichende Tierphysiologie. Springer-Verlag Heidelberg, 2 volumes.

Kandel ER et al. (eds.): Neurowissenschaften. Spektrum Verlag Heidelberg, Berlin, Oxford.

Simmons, P Young, D: Nerve Cells and Animal Behaviour. Cambridge University Press, Cambridge.

Nicholls JG, Martin RA, Wallace BG, From neuron to brain / Vom Neuron zum Gehirn. Spektrum Verlag, Heidelberg, Berlin, Oxford.

Specific literature for seminar topics


BIO.0029.002 Sensorimotor Systems and Behavioral Control (lecture), 2 credit hours, 3 credit points

BIO.0029.003 Advanced Neurobiology (seminar), 2 credit hours, 3 credit points



Sum: 180 hours

Assessment Written exam, graded.

Examination 14018 Methods in Neurobiology


Basis for Research project in Neurobiology

- 35 -

Module Practical Skills in Neurobiology

Code 74019


ECTS credits 6

Credit hours

Duration 1 semester


Coordinator Prof. Günter Ehret

Lecturer Prof. Günter Ehret, Prof. Harald Wolf


Biophysics M.Sc., elective module, 3rd semester





have experimental experience in electrophysiological and neuroanatomical methods to functionally characterize neurons and neural systems, and in-depth skills in the simulation of neuronal networks

are able to carry out scientific experiments largely independently


Energetics and allometry of animal movement

basic biomechanics of walking and flight

basic principles of animal migration and navigation

mechanisms of sensory and sensorimotor integration and of motor control in arthropods

ion channels and their contribution to neuronal excitation

Literature Baars, Gage: Cognition, Brain and Consciousness, Academic Press, New York

Birbaumer N, Schmidt RF: Biologische Psychologie , SpringerVerlag, Berlin.

Dudel-Menzel-Schmidt: Neurowissenschaft , Springer-Verlag, Berlin..

Hobson JA: Consciousness, Scientific American Library, New York.

Nieuwenhuys, Voogd, Van Huijzen: Das Zentralnervensystem des Menschen. Springer-Verlag, Berlin

Roland PE: Brain Activation, Wiley, New York

Simmons, P. Young, D.: Nerve Cells and Animal Behaviour. Cambridge University Press, Cambridge.

Specific literature for the experiments and seminar


Advanced Neurobiology laboratory course (6 hours/week)



Sum: 180 hours

Assessment Written or oral examination, graded.

Examination 14019 Practical Skills in Neurobiology


Basis for Research project in Neurobiology

- 37 -

Biomaterials

Module Biosensors and Biochips

Code 73028


ECTS credits 8

Credit hours 4

Duration 1 semester


Coordinator Dr. Alberto Pasquarelli

Lecturer Dr. Alberto Pasquarelli


M. Sc. Biophysics, elective course, 3rd semester

M. Sc. Advanced Materials, elective module, 3rd semester



Basic knowledge of chemistry and biochemistry help understanding the biological part of biosensors.

Learning objectives The world-wide needs for chemical detection and analysis rise steadily. Several resons lead to this trend, for instance the rapid increase in the prevalence of diabetes, the increasing need for environmental and health monitoring, new legislative standards for food and drugs quality control or even the early detection of biological and chemical terror attacs. Thanks to higher sensitivity and specificity, short response times and reduction of overall costs, biosensors can be very competitive in addressing these needs when compared to traditional methods.

Students can describe basic principles, mechanisms of action and applications of biosensors in different scenarios. After taking this module, participants can analyze biosensors, break-down in the elementary components and identify and illustrate every individual function in the information flow, from recognition to transduction and transmission. Students illustrate the clinical and industrial applications differentiate biosensor market sectors, e.g. commodities for everyday consumer needs or professional equipments for research. Furthermore, they are able to understand and critically analyze research in biosensors. Finally students are able to develop appropriate concepts and independently propose solutions for given problems.

Syllabus Introduction to biosensors

Applications overview

Biological detection methods: catalytic, immunologic, etc

Physical transduction methods: electrochemical, optical, gravimetric, etc.

Immobilization techniques: adsorption, entrapment, cross-linking, covalent bonds

Biochip technologies: DNA and protein chips, Ion-channel devices, MEA and MTA, Implants

Laboratory practice with assigned projects carried-out in small groups with final report and demonstration in the class

Extras: Student seminars, invited talk(s), excursion

Literature Lecture Notes

Further suggested books for deeper inside view:

Handbook of Biosensors and Biochips, ISBN 9780470019054

Alberts: Molecular biology of the cell 5th ed., ISBN 9780815341055

Gizeli: Biomolecular sensors, ISBN 074840791X

Renneberg: Biosensing for the 21st Century, ISBN: 9783540752011

Orellana: Frontiers in Chemical Sensors, ISBN: 9783540277576

Homola: Surf. Plasmon Resonance Based Sensors, ISBN: 9783540339199

Hierlemann: Int. Chem. Micr. Syst. in CMOS Techn., ISBN: 9783540273721

Steinem: Piezoelectric Sensors, ISBN: 9783540365686

Jay: Modern Food Microbiology, ISBN: 9780387234137

Morrison: Defense against Bioterror, ISBN: 9781402033841

Willner and Katz: Bioelectronics, ISBN: 3-527-30690-0


Lecture (4 hours per week)

Lab Project (20 h)

Student Seminar

Excursion (full day, not compulsory)


Preparation and Evaluation: 120 h


Total: 240 hours

Assessment The grade of the module will be the grade of the written exam. No prerequisites are necessary for exam registration.

Examination 13284 Biomaterials and Biochips

13479 Biosensors and Biochips (Precourse)


Basis for Research Project in Biosensors.

- 39 -

Module Polymers in Medicine

Code 70948


ECTS credits 2

Credit hours 1

Duration 1 semester


Coordinator Dr. Stefan Beck

Lecturer Dr. Stefan Beck


M. Sc. Biophysics, elective course, 3rd semester

M. Sc. Advanced Materials, elective module, 3rd semester



Learning objectives The course will give an idea about daily challenges in industrial R&D on polymeric biomaterials. Biomaterials are substances other than food or drugs contained in therapeutic or diagnostic systems that are in contact with tissue or biological fluids. Biomaterials play a central role in extra corporeal devices, from contact lenses to kidney dialyses, and are essential components of implants, from vascular grafts to cardiac pacemakers and fracture fixation devices1. The development and availability of modern high tech polymers allowed improving the patients care in all fields of medicine.

Syllabus In this course we will (1) gain an overview of the use of polymeric biomaterials in medicine, (2) discuss some examples of permanent and resorbable polymer implants in more detail, (3) take a look at legal and regulatory aspects, (4) learn about functional and design requirements when dealing with polymers in medicine, and (5) will look into some future concepts.

Literature Will be announced by the lecturer




Preparation and Evaluation: 45 h

Total: 60 hours


Examination 10909 Polymers in Medicine


Basis for Research Project in Biomaterials.

- 41 -

Physics Department

Physics

Module Biophotonics

Code 71502


ECTS credits 6

Credit hours 6

Duration 1 semester


Coordinator Prof. Alwin Kienle

Lecturer Prof. Alwin Kienle


Physics M.Sc., elective module, 1st or 2nd semester

Biophysics M.Sc., elecive module, 1st - 3rd semester



Fundamentals of Electrodynamics and Optics


understand the basics of Tissue Optics

know the medical applications of optical methods

are able to solve numerically differential equations with the Monte-Carlo method

are able to solve analytically differential equations in scattering problems with integral transforms

Syllabus Description of light propagation in scattering media based on Maxwell’s equations, radiative transport theory and diffusion theory

Determination of the optical properties of scattering media

Light scattering from particles of different shapes

Color origin in scattering media

Literature


Lecture (3 hours per week): PHYS5227.0 Biophotonics

Exercise (1 hour per week)

Laboratory course (2 hours per week)


15 hours exercise (attendance time)

30 hours laboratory course (attendance time)


Total: 180 hours


Examination 12112 Biophotonics (precourse)

12102 Biophotonics


Basis for Research thesis in Biophotonics

- 43 -

Module NMR Spectroscopy and Imaging Methods

Code 72557


ECTS credits 6

Credit hours 6

Duration 1 semester


Coordinator Dean of Physics Studies

Lecturer Prof. Volker Rasche


Physics M.Sc., elective module, 1st or 2nd semester

Biophysics M.Sc., elecive module, 1st - 3rd semester



Learning objectives Students who successfully pass this module:

know the basic concepts of imaging techniques in medicine and various system architectures

understand the application of various imaging methods

understand the fundamentals of magnetic resonance spectroscopy

are able to handle a magnetic resonance tomography

Syllabus The lecture deals with the basic principles of imaging techniques currently used in medicine. Imaging techniques in medicine allow for generating image-based information about the anatomy and function of the human body. The methods involved are based on different physical principles.

X-rays (X-classical and computer based tomography (CT))

Nuclear Magnetic Resonance imaging (MRI)

Ultrasound (ultrasound and echocardiography)

Positron Emission Tomography (PET)

Single Photon Emission Computed Tomography (SPECT)

Introduction to NMR: QM description of spins, spin operators, density matrix

Semi-classical description, Bloch equations

Lineshape of NMR signal

Spin echoes

Theory of relaxation: coherence times (T2 and T1), extreme narrowing regime, intensity of NMR signal

Electronic shielding, chemical shift

Spin-Spin coupling, J coupling

Dipolar interactions, averaging by molecular motion

Magic angle spinning

Polarization transfer in NMR: nuclear Overhauser effect, Solomon equations, Hartmann-Hahn resonance, solid effect, optical hyperpolarization

Two dimensional NMR, COSY experiment

New detection methods for NMR: Magnetic resonance force microscopy (MRFM), NV centres in diamond

Literature



Exercise (2 hour per week)


30 hours exercise (attendance time)


Total: 180 hours


Examination 13832 NMR Spectroscopy and Imaging Methods (precourse)

13831 NMR Spectroscopy and Imaging Methods


Basis for Research thesis in Biophotonics

- 45 -

Module Gene Expression

Code 74004


ECTS credits 3

Credit hours 2

Duration 1 semester



Lecturer Prof. Jens Michaelis


Biophysics M.Sc., elective module, 2nd Semester



Module Biophysics: Fundamentals


understand complex experimental setups in modern Biophysics

can apply fundamental biophysical methods to current molecular biological and cell biological issues

are able to describe biological phenomena using physical models of varying complexity

Syllabus Molecular basics and structural Biology of gene expression

RNA polymerase as molecular motor

FRET studies of transcription dynamics

Simple model of gene expression I and II

Gene expression in bacteria- Live single cell experiments

Gene expression in eukaryotes- Live single cell experiments

Whole genome analysis – Methods and Applications

Transcriptome analysis, methods for real time information

Single cell RNA sequencing

Introduction to Optogenetics

Literature Phillips, Kondev, Theriot: Physical Biology of the Cell, Garland 2013

Alberts: Molecular Biology of the Cell, Garland Publishing 2008

Latchman: Gene control, Garöland Science 2010

Armstrong: Epigenetics, Garland Science 2014

Buc and Strick: RNA Polymerases as Molecular Motors, RSC Publishing 2009

Selvin and Ha: Single-Molecule Techniques, Cold Spring Harbor Laboratory Press 2008

Papers: special papers, see lecture slides for sources


Lecture (2 hours per week): PHYS5118.0 Gene Expressions


60 hours self-study

Total: 90 hours

Assessment Graded written examination

Examination 14004 Gene Expression


Basis for Research in the field of Biophysics

- 47 -

Module Molecular Motors

Code 74003


ECTS credits 3

Credit hours 2

Duration 1 semester



Lecturer Prof. Christof Gebhardt



Physics M.Sc., elective module, 2nd Semester




Learning objectives Students who have successfully completed this module

understand complex experimental setups in modern Biophysics

can apply fundamental biophysical methods to current molecular biological and cell biological issues

are able to describe biological phenomena using physical models of varying complexity

Syllabus Modern methods of Biophysics

Electrophysiology

Single molecule methods

Stochastic methods and descriptions

Microfluidics

Motor proteins

Molecular mechanisms of gene expression

Biophysics of cell division

Modern microscopy methodologies

Introduction to Bioinformatics and Statistics

Literature Phillips, Kondev, Theriot: Physical Biology of the Cell, Garland Science

Howard: Mechanism of Motor Proteins and the Cytoskeleton, Sinaur and Associates

Lakowicsz: Principles of Fluorescence Spectroscopy, Springer US


Lecture (2 hours per week): PHYS5128.0 Molecular Motors



Total: 90 hours

Assessment Written or oral examination.

Examination 14003 Molecular Motors



- 49 -

Module Cellular Biophysics

Code 74005


ECTS credits 3

Credit hours 2

Duration 1 semester



Lecturer Prof. Kay Gottschalk



Physics M.Sc., elective module, 2nd Semester




Learning objectives The cell is the smallest living unit in the body. It fulfills a variety of specialized functions and interacts with the environment. Classically, biochemical interactions with the environment by soluble factors like hormones are considered. However, physical parameters like stiffness or shape also play an important role. The goal of the lecture is to highlight these physical triggers of cell function.

Syllabus In this module, the following topics will be covered:

The cell as a composite material: structure and function of the cytoskeleton

Influence of Cell Shape on Cell Function

Mechanosignalling: Influence of substrate rigidity on cell function and mechanics

Measurement of Cell mechanics: atomic force microscopy and microrheology

Measurements of Cellular Forces: Traction Force Microscopy

Literature Phillips, Kondev, Theriot: Physical Biology of the Cell, Garland 2013

Alberts: Molecular Biology of the Cell, Garland Publishing 2008

Papers: special papers, see lecture slides for sources





Total: 90 hours


Examination 14005 Cellular Biophysics


- 51 -

Module Biophysics of Hearing and Seeing

Code 74268


ECTS credits 4

Credit hours 3

Duration 1 semester

Cycle irregular


Lecturer Prof. Heinrich Hoerber


Biophysics M.Sc., elective module

Physics M.Sc., elective module

Wirtschaftsphysik M.Sc., elective module



Learning objectives The course on Biophysics of Hearing and Seeing will provide a basic understanding of these senses with respect to their anatomy and physiology. In comparison with recent technical developments of optical and acoustic sensor systems, the physical principals to characterize the performance of these senses will be introduced.

Syllabus Evolution of seeing

New developments in imaging and image processing techniques

Anatomy and Physiology of the Eye

Comparison between natural and artificial systems

Introduction to Acoustic

Anatomy and Physiology of the Ear

Comparison between natural and artificial systems

Literature Anatomy and Physiology of Eye, 2nd Edition 1.12.2008, A.K. Khurana, CBS publishers & Distributors

Eye and Brain, The Physiology of Seeing, 5th Edition 30.10.1997, Richard L. Gregory, Oxford University Press

The Evolution of the Eye, 8.10.2015, Georg Glaeser und Hannes F. Paulus, Springer

Essential Principles of Image Sensors, 12.8.2014, Takao Kuroda, Apple Academic Press

Hearing. Anatomy, Physiology and Disorders of the Auditory System, Aage R. Moller, Plural Publishing, 1.10.2011

Fundamentals of Hearing,William Yost, Academic Press, 2.10.2006


Lecture with exercises, block course

Workload 60 hours lecture with exercises (attendance time)


Total: 120 hours

Assessment Written or oral examination.

Examination 14268 Biophysics of Hearing and Seeing



- 53 -

Module Basics of Scanning Electron Microscopy

Code 72035


ECTS credits 2

Credit hours 2

Duration 1 semester

Cycle Summer Semester


Lecturer Prof.Ute Kaiser



Advanced Materials M.Sc., elective module

Physics M.Sc., general elective module



None

Learning objectives Students who have successfully completed this module are able to

describe the function of basic components of a scanning electron microscope,

understand basic SEM modes imaging, diffraction and spectroscopy.


Components of the SEM

Physical phenomena of electron-matter interaction

Literature Will be announced in the lab course.


Lecture (2 hours/week)



Total: 60 hours

Assessment The grade of the module will be the grade of the oral or written (depending on the number of participants) exam. No prerequisites are necessary for exam registration.

Examination 12701 Basics of Scanning Electron Microscopy


Basis for Research in the field of Biophysics/Physics.

- 55 -

Module Lab Principles of Transmission Electron Microscopy

Code 73443


ECTS credits 2

Credit hours 2

Duration 1 semester

Cycle Winter Semester









None


prepare a cross-sectional TEM sample

perform bright-field and dark-field images and diffraction patterns in order to understand the defects in the specimen

determine the spherical aberration coefficient

determine the chemical content by EDX analysis


Modes of TEM operation: imaging, diffraction and spectroscopy

TEM sample preparation

Hands-on experience in imaging, diffraction and spectroscopy

Determination of the spherical aberration coefficient of the objective lens in an uncorrected TEM, comparison to the aberration-corrected objective lens.

Literature Will be announced in the lab course.


1 week TEM Lab

Workload 30 lab course (attendance time)


Total: 60 hours

Assessment The grade of the module will be the grade of the exam. No prerequisites are necessary for exam registration.

Examination 13443 Lab Principles of Transmission Electron Microscopy



- 57 -

Module Principles of Transmission Electron Microscopy and Seminar

Code 74121


ECTS credits 4

Credit hours 3

Duration 1 semester

Cycle Winter Semester









None


describe the function of basic components of a transmission electron microscope,

understand basic TEM modes imaging, diffraction and spectroscopy.


Components of the TEM including the aberration corrector

Physical phenomena of electron-matter interaction

Literature Williams, David B., Carter, C. Barry: Transmission Electron Microscopy

A Textbook for Materials Science, four volumes, Springer, 2nd ed. 2009.


Lecture (2 hours/week)

Exercise (1 hour/week)

Exercise (1 hour/week)Workload

30 lecture (attendance time)

15 seminar (attendance time)


Total: 120 hours

Assessment The grade of the module will be the grade of the exam. No prerequisites are necessary for exam registration.

Examination 14121 Principles of Transmission Electron Microscopy and Seminar



- 59 -

Chemistry Department

Organic Chemistry

Module Biopolymers

Code 71308


ECTS credits 3

Credit hours 2

Duration 1 semester


Coordinator Prof. Tanja Weil

Lecturer Prof. Tanja Weil


M. Sc. Chemistry, Electoral duty or deepening module, 1st -3rd semester

M. Sc. Biology, minor subject chemistry, deepening macromolecular chemistry, 2nd semester

M. Sc. Biochemistry, minor subject chemistry, 2nd semester

M. Sc. Biophysics, elective module, 2nd semester



Bachelor modules in Organic and/or Macromolecular Chemistry


know the representation, the structure and the function of nucleic acids, proteins and other biomacromolecules

know the analytic methods for this molecule class

Syllabus Representation, structure and function of biopolymers

Physical and chemical description of methods

Structural determination and chemical changes

Literature Will be announced in the lecture.


Lecture (2 hours per week): CHEM8340.001 Biomacromolecules



Sum: 90 hours


Examination 12034 Biopolymers


Basis for Research project in the fields of Organic and Biological Chemistry

- 61 -

Module Biological Chemistry

Code 71328


ECTS credits 3

Credit hours 2

Duration 1 semester



Lecturer Prof. Tanja Weil


M. Sc. Chemistry, 1st -3rd Semester

M. Sc. Biophysics, elective module, 2nd semester



Bachelor modules in Organic and/or Macromolecular Chemistry

Learning objectives Students who successfully passed this module understand how chemical technologies can use molecules and macromolecules to influence biological systems.

Syllabus Theory, appearance and application in biological systems of

Genomics

Proteomics

chemical libraries

Peptide libraries

kombinatoric chemistry

Parallel synthesis

biologically active peptide

unnatural proteins and peptide

Pharmacophores

Protacs

Post translational changes

Literature 1. Herbert Waldmann: Chemical Biology. Learning through Case Studies (Wiley)

2. Scientific papers


Lecture (2 hours per week): CHEM8500.001 Biological Chemistry



Sum: 90 hours


Examination 12036 Biological Chemistry


Basis for Research project in the fields of Organic and Biological Chemistry

- 63 -

Module Project Work in Macromolecular Chemistry

Code 71329

Instruction language English or German

ECTS credits 9

Credit hours 12

Duration 1 semester

Cycle Each semester


Lecturer Lecturers of the Macromolecular Chemistry


M. Sc. Chemistry, electoral duty module 1st -3rd Semester

M. Sc. Biophysics, elective module, 3rd semester



Bachelor lab courses in Organic and/or Macromolecular Chemistry

Learning objectives Students who successfully passed this module have the skills and the competence

to work independently on a theoretical and/or experimental project in Organic and/or Macromolecular Chemistry

write and defend a scientific essay and present it in a talk

Syllabus Practical research project on a topic of the Organic and/or Macromolecular Chemistry from the working groups.

Literature


CHEM6840.001 Project work in Macromolecular Chemistry (lab course) (12 hours per week) with written elaboration and presentation in the working group or institute



Sum: 270 hours

Assessment Written elaboration of the project.

Examination 12038 Projekt Work in Macromolecular Chemistry

Grading procedure Ungraded module

Basis for Research thesis in Organic Chemistry

- 65 -

Anorganic Chemistry

Module Analytical Spectroscopy

Code 71293


ECTS credits 3

Credit hours 2

Duration 1 semester


Coordinator Prof. Boris Mizaikoff

Lecturer Prof. Boris Mizaikoff



M. Sc. Chemistry and Management, deepening module




Bachelor modules in Analytical Chemistry

Learning objectives The interaction of electromagnetic radiation with molecules, ions, and atoms is among the fundamental physical principles for generating highly specific information on the species present within a solid, liquid or gaseous sample.

Syllabus This lecture will repeat and discuss in more depth the fundamentals of spectroscopic techniques, interaction of light with matter, and optical elements, and will then expand into advanced analytical spectroscopies including e.g., IR- and Raman and fluorescence spectroscopy, surface enhanced optical techniques, and laser-based measurement techniques.

Literature Will be announced in the course


Lecture, 2 hours per week.



Sum: 90 hours

Assessment Written or oral exam.

Examination 12029 Analytical Spectroscopy

Grading procedure The total grade of the module is the result of the exam.

Basis for Research thesis in Analytical Chemistry

- 67 -

Module Inorganic Materials Synthesis/Inorganic Nanomaterials

Code 71300


ECTS credits 3

Credit hours 2

Duration 1 semester


Coordinator The Dean of Studies of Chemistry

Lecturer Prof. Mika Lindén







Bachelor modules in the field related to the subject

Learning objectives Students who have successfully completed this module,

will learn important synthesis paradigms and advanced characterization techniques in relation to functional nanomaterials.

Syllabus This module provides the following content:

nanoparticle synthesis methods

film formation techniques

functional nanosystems

nanomaterial characterization.

Literature Brinker & Scherer: Sol-Gel Science

Ozin: Nanochemistry





Sum: 90 hours

Assessment Written or oral exam.

Examination 12014 Anorganische Nanomaterialien

Grading procedure The credit points will be awarded once the written exam has been passed. No prerequisites are necessary for exam registration.

Basis for Research thesis in Inorganic Materials

- 69 -

Module Special Topics in Analytical Chemistry IV

Code 71290


ECTS credits 3

Credit hours 2

Duration 1 semester



Lecturer Dr. Christine Kranz


M. Sc. Chemistry, electoral duty module os deepening module, 1st -3rd Semester






Learning objectives This lecture gives an introduction to the fundamental principles of scanning probe microscopy and their applications. A special focus is on techniques and application areas that are frequently used in analytical chemistry.

Syllabus Among these techniques, atomic force microscopy (AFM), scanning tunneling microscopy (STM), nearfield scanning optical microscopy (NSOM), and scanning electrochemical microscopy (SECM) along with hyphenated techniques combining some of these measurement principles will be discussed. Example from recent literature will furthermore highlight the importance of these tools in modern analytical chemistry.






Sum: 90 hours

Assessment Presentation, Proposal or oral exam.

Examination 12208 Analitic aspects of the Scanning Probe Microscopy



- 71 -

Module Special Topics in Analytical Chemistry V

Code 71539


ECTS credits 3

Credit hours 2

Duration 1 semester



Lecturer Prof. Kerstin Leopold


M. Sc. Chemistry, electoral duty module os deepening module, 1st -3rd Semester






Learning objectives This lecture gives an overview of the methods applied in ultra trace analysis of elements, i.e. analytical procedures for the determination of elements in a concentration range lower than 1 mg L-1. Such methods are applied in a broad variety of fields, such as environmental analysis, forensic analysis, semiconductor technique, biology, medicine and medical analysis, archaeology, geology, ect.

Syllabus The lecture will give examples of different applications and will explain special working procedures, like for example working in a clean room, or how to collect a sample without contaminating it. Furthermore, possible sources of contamination and analyte losses will be shown as well as the methodology to identify such systematic errors. The analytical procedure, from collection of the sample to processing the data will be discussed in regard to the speciality of ultra trace concentration.






Sum: 90 hours

Assessment Presentation, Proposal or oral exam.

Examination 12209 Ultra Trace Analysis



- 73 -

Stochastics and Bioinformatics

Module Evolutionäre Algorithmen

Code 72014

Instruction language German

ECTS credits 6

Credit hours 4

Duration 1 semester


Coordinator Prof. Hans Armin Kestler

Lecturer Prof. Hans Armin Kestler, Dr. Harald Hüning



Informatik, M.Sc., Kernfach Theoretische und Mathematische Methoden der Informatik

Software-Engineering, M.Sc., Kernfach Theoretische und Mathematische Methoden der Informatik

Medieninformatik, M.Sc., Kernfach Theoretische und Mathematische Methoden der Informatik

Medieninformatik, B.Sc., Schwerpunkt

Informatik, B.Sc., Schwerpunkt

Software-Engineering, B.Sc., Schwerpunkt Software-Engineering

Informatik, Lehramt, Wahlmodul

Formal prerequisites Algorithms and Data Structure


Learning objectives Die Studierenden sind in der Lage, evolutionäre Algorithmen und Methoden zu beschreiben und umzusetzen. Sie können selbst bewerten, ob zur Lösung eines gegebenen Problems der Einsatz evolutionärer Algorithmen angebracht ist. Sie finden selbständig geeignete Repräsentationen für ein gegebenes Problem und können die verschiedene Bausteine eines evolutionären Algorithmus auf ein Problem anpassen bzw. geeignete Bausteine auswählen. Die Studierenden sind in der Lage, aktuelle Forschungsliteratur auf diesem Gebiet zu verstehen und umzusetzen.

Syllabus aktuelle evolutionäre Algorithmen

Aufbau eines evolutionären Algorithmus

Problemrepräsentationen

Literature AE Eiben, JE Smith, Introduction to Evolutionary Computing, Springer 2003

K DeJong, Evolutionary Computation – A Unified Approach, MIT Press 2006


Lecture (2 h/week)

Excercises (2 h/week)




Total: 180 hours


Examination 11309 Evolutionäre Algorithmen

Grading procedure

Basis for Selected research project in Medical System Biology

- 75 -

Module Bioinformatics and System Biology

Code 72138


ECTS credits 6

Credit hours 4

Duration 1 semester



Lecturer Prof. Hans Armin Kestler, Prof. Michael Kühl, Prof. Lars Bullinger, Prof. Franz Oswald, Dr. Karlheinz Holzmann, Prof. Enno Ohlebusch, Jun. Prof. Medhanie Mulaw, Dr. Anna Dolnik, Dr. Alexander Groß, Dr. Johann Kraus, Dr. Ludwig Lausser, Dr. Eric Sträng, Dr. Sebastian Wiese, Andre Burkovski, Axel Fürstberger, Florian Schmid, Lyn-Rouven Schirra



Molecular Medicine, M.Sc., compulsory module 1st Semester.



Basic knowledge of molecular biology and bioinformatics

Learning objectives Students should be able to

describe the most important concepts in bioinformatics and systems biology

apply, discuss and interpret state-of-the-art techniques out the field of bioinformatics and systems biology

interpret basic mathematical networks and models

Syllabus principles of molecular biology

data mining techniques

sequence alignment

phylogenetic inference and structural anaylsis

signal transduction

pathway analysis

modeling- and reconstruction techniques

Literature Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., Walter, P.: Molecular Biology of the Cell, 6th Edition. Garland Science (2014)

Agostino, M.: Practical Bioinformatics, Garland Science (2013)

Draghici, S.: Statistics and Data Analysis for Microarrays Using R and Bioconductor. Chapman and Hall/CRC (2011)

Voit, E.: A First Course in Systems Biology, 2nd Edition. Garland Science (2012)


Lecture and Excercises (4 h/week)

Workload 60 hours lecture and exercise (attendance time)


Total: 180 hours


Examination 13705 Bioinformatics and Systems Biology

Grading procedure


- 77 -

Module Praktische Algorithmen der Bioinformatik und Computerlinguistik mit Lisp

Code 71859


ECTS credits 6

Credit hours 4

Duration 1 semester



Lecturer Dr. Markus Maucher

Prof. Hans Armin Kestler

Dr. Tilman Becker (DFKI)



Informatik, M.Sc., Kernfach Praktische und Angewandte Informatik

Medieninformatik, M.Sc., Kernfach Praktische und Angewandte Informatik

Software-Engineering, M.Sc., Kernfach Praktische und Angewandte Informatik

Informatik, B.Sc., Schwerpunkt

Medieninformatik, B.Sc., Schwerpunkt

Software-Engineering, B.Sc., Schwerpunkt

Formal prerequisites Introduction to Informatics


None

Learning objectives Die Studierenden sind in der Lage, in Lisp geschriebene Programme nachzuvollziehen und können eigene Programme in Lisp schreiben. Sie kennen die Lisp-interne Repräsentation von Daten, können Funktionen höherer Ordnung und anonyme Funktionen definieren und verwenden. Die Studierenden verstehen die Grundzüge des Common Lisp Object Systems (CLOS). Sie können außerdem ein bestehendes Lisp-System mit Hilfe von Makros erweitern.

Syllabus Geschichtliches

Kontrollstrukturen

Funktionen höherer Ordnung, anonyme Funktionen

Variablen und lexikalische Sichtbarkeit, LET

Debugging/Compiling

Imperative Programmierung

Ein-/Ausgabe

Datentypen

Objektorientierte Programmierung

Makros

Literature C. Emerick, B. Carper, C. Grand, Clojure Programming, OReilly, 2012

P. Seibel, Practical Common Lisp, Apress, 2005

C. Barski, Land of Lisp, No Starch Press, 2011

I. J. Kalet, Principles of Biomedical Informatics, Academic press, 2008


Lecture and Excercises (4 h/week)



Total: 180 hours


Examination 12815 Praktische Algorithmen der Bioinformatik und Computerlinguistik mit Lisp

Grading procedure


- 79 -

Module Learning Systems I

Code 74212


ECTS credits 6

Credit hours 4

Duration 1 semester


Coordinator Prof. Daniel Braun

Lecturer Prof. Daniel Braun



Informatik, M.Sc., elective module

Medieninformatik, M.Sc., elective module

Software-Engineering, M.Sc., elective module



Linear algebra, analysis, probability theory

Learning objectives Students acquire knowledge about different learning models in biological

and technical systems (professional competence). In exercises, students

are able to implement different learning concepts (methodological expertise).

Students are able to make use of biological principles and transfer them to

technical applications (transfer and evaluation competence).

Syllabus Induction and learning in logic-based systems

Adaptive control systems

Statistical learning

Unsupervised learning

Reinforcement learning

Bayesian learning

Kernel learning

Robot learning

Animal and human learning

Learning in neural networks

Literature Bishop “Pattern recognition and machine learning”

Russell & Norvig “Artificial intelligence. A modern approach”

Dayan & Abbott “Theoretical neuroscience”

Reznikova “Animal intelligence”


Lecture (3 h/week)

Exercise (1 h/week)



Total: 180 hours

Assessment The grade of the module will be the grade of the written or oral exam. No prerequisites are necessary for exam registration.

Examination 14212 Learning Systems I

Grading procedure

Basis for Selected research project in Neural Information Processing

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Module Learning Systems II

Code 74258


ECTS credits 6

Credit hours 4

Duration 1 semester



Lecturer Prof. Daniel Braun









Learning objectives Students acquire knowledge about different learning models in biological

and technical systems (professional competence). In exercises, students

are able to implement different learning concepts (methodological expertise).

Students are able to make use of biological principles and transfer them to

technical applications (transfer and evaluation competence).

Syllabus Learning in animals

Learning in humans

Learning in robots

Multi-agent learning

Learning in evolutionary systems

Learning-to-learn

Hierarchical learning

Structure learning

Non-parametric learning

Information-theoretic learning models

Computational learning theory

Literature Bishop “Pattern recognition and machine learning”

Murphy “Machine Learning. A probabilistic perspective””

Dayan & Abbott “Theoretical neuroscience”

Reznikova “Animal intelligence”

Haykin “Neural networks and learning machines”


Lecture (3 h/week)

Exercise (1 h/week)



Total: 180 hours


Examination 14258 Learning Systems II

Grading procedure


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Module Neurotechnology: Brain-Machine-Interfacing

Code 74257


ECTS credits 6

Credit hours 4

Duration 1 semester

Cycle irregular


Lecturer Sonja Schach









Learning objectives Students acquire knowledge about principles and different algorithms for

decoding of brain signals (professional competence). In exercises, students

are able to implement brain decoding algorithms on an EEG platform (methodological

expertise). Students are able to make use of biological and

algorithmic principles and transfer them to technical applications (transfer

and evaluation competence).

Syllabus Recording brain signals

Signal processing of brain signals

Machine learning methods for brain decoding

Design principles for brain computer interfaces

Programming a non-invasive EEG brain computer interface

Applications and ethical issues

Literature Rao “Brain Computer Interfacing. An Introduction.”


Lecture (2 h/week)

Exercise (2 h/week)



Total: 180 hours


Examination 14257 Neurotechnology: Brain-Machine-Interfacing

Grading procedure


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Module Einführung in die Neuroinformatik

Code 70330


ECTS credits 6

Credit hours 4

Duration 1 semester


Coordinator Dr. Friedhelm Schwenker

Lecturer Dr. Friedhelm Schwenker



Informatik, M.Sc., FSPO 2014/Kernfach/Praktische und Angewandte Informatik

Medieninformatik, M.Sc., FSPO 2014/Kernfach/Praktische und Angewandte Informatik

Softwareengineering, M.Sc., FSPO 2014/Kernfach/Praktische und Angewandte Informatik



Basic knowledge of Informatics and Mathematics".

Learning objectives Die Studierenden sind in der Lage, die biologischen Grundlagen eines neuronalen Netzes zu beschreiben und kennen einfache Neuronenmodelle und Netzwerkarchitekturen. Sie kennen verschiedene unüberwachte und überwachte Lernverfahren. Die Studierenden wenden die vorgestellten Algorithmen auf einfache Problemstellungen an und evaluieren die Performanz dieser Verfahren mit Hilfe statistischer Methoden.

Syllabus Grundlagen biologischer neuronaler Netze

Neuronenmodelle und Architekturen neuronaler Netze

Lokale Lernregeln

Überwachte Lernverfahren

Unüberwachte und kompetitive Lernverfahren

Neuronale Assoziativspeicher

Anwendungen, Datenvorverarbeitung und statistische Evaluierung

Literature Raul Rojas: Theorie der neuronalen Netze, Springer, 1996

Zell, Andreas: Simulation neuronaler Netze, Oldenbourg Verlag, 1997

Bishop, Chris: Neural Networks for Pattern Recognition, Oxford University Press, 1995

Kohonen, Teuvo: Self Organizing Maps, Springer, 1995

Skript zur Vorlesung SoSe 2013


Lecture (2 hours/week

Excercises (2 hours/week)




Total:180 hours

Assessment The grade of the module will be the grade of the written exam. No prerequisites are necessary for exam registration

Examination 10590 Einführung in die Neuroinformatik

Grading procedure

Basis for Selected research project in the Bioinformatics specialization area.

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Adaptation Modules

Biochemistry, Chemistry or Molecular Biology

Module Introductory Chemistry

Code 71944


ECTS credits 3

Credit hours 2

Duration 1 semester


Coordinator Prof. M. Fichtner, Faculty of Natural Sciences

Lecturer Prof. M. Fichtner, Faculty of Natural Sciences


Energy Science and Technology M.Sc., 1st semester



Fundamentals in mathematics, physics and chemistry

Learning objectives Students who have successfully completed this module

are able to discuss a given chemical element with respect to its position in the periodic table of elements, structure of its electron shell and its ability to form chemical bonds

can describe the equilibrium of a given reaction according to the mass action law

use the idea of the pH-value and the acid/base-pKa/pKb-value to analyze the properties of water, oxo-acids, week acids and bases, buffers and indicators

can identify a redox reaction and analyze it with respect to the redox potential of the individual reactants and the difference in redox potential of the overall reaction

Syllabus Structure of matter, states of matter, phase diagrams, separation techniques

Atom structure (qualitative): Bohr's atom model, hydrogen atom, isotopes , periodic table of the elements

Formation of chemical bonds, bond order, molecular orbital

Chemical bonding: Compounds with covalent bonds, inorganic salts, van der Waals forces, Metals/semiconductors

Chemical reaction: Reaction equilibrium, mass action law, principle of LeChatelier

Water: Structure and properties, pH-value

Acids and bases: theories, pKa- and pKb-values, oxo-acids, weak acids and bases, buffers, indicators, titrations

Redox-reactions: Oxidation, reduction, oxidation numbers, redox potential, Nernst´s equation,

Selected large scale reactions

Organic chemistry nomenclature, functional groups, principle reactions

Literature Malone, Leo, J., Dolter, Theodore: Basic Chemistry, 9th Edition International Student Version, Wiley, 2012


Lecture (2 hours per week): CHEM8528.001 Introductory Chemistry

Workload 30 h attendance

45 h preparation and revision

15 h exam preparation

Total: 90 hours

Assessment

Examination 13018 Introductory Chemistry

Grading procedure

Basis for Module Chemistry I

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Module Practical Skills in Molecular Biology

Code New


ECTS credits 2

Credit hours 2

Duration 1 semester

Cycle Summer or winter semester


Lecturer Prof. Jens Michaelis, Dr. Carlheinz Röcker


Biophysics M.Sc., adaptation module for physics graduate, 1st or 2nd semester



None

Learning objectives Students who successfully passed this module have practical experience in basic biological experimental techniques relevant to Biophysics

Syllabus Gene expression: Basics of genetic engineering, transformation of bacteria, protein expression, purification and characterization

Live cell imaging: Intracellular calcium signals after receptor stimulation, molecular targeting by transfection with a conjugated fluorescent protein

Literature Lab manuals


3 days of experimental work including introductory and final discussions

Workload 24 h lab (presence):

36 h private study

Total: 60 h

Assessment Lab reports

Examination 14267 Practical Skills in Molecular Biology

Grading procedure The module is ungraded

Basis for

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Module Biology and Cell Biology

Code 71409


ECTS credits 5

Credit hours 4

Duration 1 semester



Lecturer Prof. Bernhardt Koch, Prof. Paul Walther, PD Dr. Andreas Ziegler


Biophysics M.Sc., elective module for physics graduates, 1st semester



None


are able to understand central problems of Biology and Cell Biology

understand links between different fields of Biosciences

are prepared for lectures in Biomaterials in 2nd and 3rd semester

Syllabus Basics and Ecosystems

Biomolecules: structure and functions of macromolecules

Cellular respiration: harvesting chemical energy

Cell morphology and gene expression: cell membrane structure and function

Organismic and animal diversity: prokaryotes and eukariotes

Animal development

Functional anatomy: animal structure and function, muscle function and nervous system

Endocrinology: chemical signals in animals

Circulation and gas exchange in animals

Intracellular compartments and protein sorting

Structure and function of the extracellular matrix

Literature N. A. Campbell, J. B. Reece: BIOLOGY, Benjamin Cummings Publisher, 6th edition (2002)

Thomas D. Pollard, William C. Earnshaw , Jennifer Lippincott-Schwartz, Cell Biology

Handouts related to specific problems are distributed in the lectures


Introductory Biology and Cell Biology (L), 4 h per week

Workload 60 h lecture (attendance)

60 h preparation and revision lecture

30 h exam preparation

Total: 150 hours

Assessment Examination of 120 min

Examination 11942 Biology and Cell Biology

Grading procedure The grade is the examination grade.

Basis for Biophysics and Biochemistry modules

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Physics and Mathematics

Module Mathematical Methods for Material Science

Code 72382


ECTS credits 5

Credit hours 4

Duration 1 semester



Lecturer


Biophysics M.Sc., elective module for non-physics graduates, 1st semester

Biochemistry M.Sc., elective module, 1st semester

Advanced Material M.Sc., elective module, 1st semester



None

Learning objectives This course gives an overview of essential mathematical methods for the solution of generic problems in Physics. Specific example of important physical applications will be given. The course aims to provide the student with the expected mathematical competency for further courses in different areas of Physics.

Syllabus Ordinary differential equations and systems of differential equations

Integration

Linear vector spaces, vector and matrix analysis

Probability and error analysis

Fourier-analysis

Functions of complex variable and integral calculus

Literature J. Nearing, Mathematical Tools for Physics, http://www.physics.miami.edu/~nearing/mathmethods/

Other bibliographical references will be given to the students for each different topic addressed in the course.


Lecture (2 hours per week), Exercise (2 hours per week)

Workload 30 hours lecture

30 hours exercise


Total: 150 hours

Assessment Successful participation in exercises (at least 70%) as prerequisite for the written examination

http://www.physics.miami.edu/~nearing/mathmethods/

Examination 13011 Mathematical Methods in Material Science

Grading procedure

Basis for

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Module Practical Skills in Physics

Code 72383


ECTS credits 4

Credit hours 3

Duration 1 semester



Lecturer Dr. Carlheinz Röcker


Biophysics M.Sc., elective module for non-physics graduates, 1st semester



None

Learning objectives Practical experience in basic physical experimental techniques relevant for Biophysics and analysis of experimental data with critical discussion.

Syllabus Mechanical oscillations

Thermic radiation

Optical interference and spectrometry

Oscillating electric circuits Students who may have already covered the basics experiments in physics, may be advised to take other experiments from the FP Physics Lab.

Literature Lab Manual


Lab work with 4 full-day experiments including introductory and final discussions.

Workload 45 hours laboratory course (attendance time)

75 hours self-study, data analysis, report writing

Total: 120 hours

Assessment Successful performance of four experiments including written reports. Each lab report has to be assessed as satisfactory by the supervisor.

Examination 13513 Practical skills in Physics

Grading procedure The module is ungraded

Basis for

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Additive Key Qualifications

Module Additive Key Qualifications

Code 86000

Instruction language

English or German

ECTS credits 3

Credit hours 2

Duration 1 semester

Cycle Each semester

Coordinator Dr. Hans-Klaus Keul, Dr. Roman Yaremko

Lecturer Lecturers from AKQ Coordination Centre, from Humboldt Study Center for Philosophy and Humanities, from Centre for Languages and Philology as well as lecturers from specific Study Commissions


Biophysics M.Sc., elective module, 1st or 2nd semester


None


None

Learning objectives

After successful completion of this module, students

acquired intercultural competences and knowledge of foreign languages.

have knowledge and skills in the following subject areas: teamwork, communication and presentation.

developed reflection, communication and argumentation competences.

Syllabus Depends on the selected course.

Literature -


Seminar (2 hours per week)

http://www.uni-ulm.de/studium/studiengaenge/schluesselqualifikationen/veranstaltungen.html



Sum: 90 hours

Assessment Graded written or oral examination.

Examination

Grading procedure

Basis for

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Research Phase

Module Biophysics Research Project

Code new


ECTS credits 15

Credit hours 15

Duration 1 semester

Cycle Each semester


Lecturer All the professors in the Institute of Biophysics


Biophysics M. Sc., 3rd Semester

Formal prerequisites This module is part of the one-year research phase


have learned to familiarize with a special area of the current international research in Biophysics

can search and understand part the international scientific literature (information competence) know the rules of good scientific practice

Syllabus Search of the suitable scientific literature and elaboration of the theoretical foundations

Concrete planning of the research project in collaboration with a team and the supervisor

Accomplishment of experimental or theoretical preliminary investigation

Presentation of the research project and intermediate results in a group seminar

Literature


Research project to be carried on either in the Institute of Biophysics, Institute for Experimental Physics, or ILM (Institute for Laser Technologies in Medicine and measurement techniques.

Workload 450 hours

Assessment This module will be examined by the professor responsible for the selected project.

It will be graded the oral presentation of the progress report accounting for the methodogical approach and the scientific execution of the project.

Examination

Grading procedure

Basis for

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Module Selected Research Project

Code new


ECTS credits 15

Credit hours 15

Duration 1 semester

Cycle Each semester


Lecturer All the professors in the selected Institute


Biophysics M. Sc., 3rd Semester

Formal prerequisites This module is part of the one-year research phase


have learned to familiarize with a special area of the current international research in the selected area of research

can search and understand part the international scientific literature (information competence)

know the rules of good scientific practice

Syllabus Search of the suitable scientific literature and elaboration of the theoretical foundations

Concrete planning of the research project in collaboration with a team and the supervisor

Accomplishment of experimental or theoretical preliminary investigation

Presentation of the research project and intermediate results in a group seminar

Literature


Research project to be carried on in either the department of Physics, Chemistry, Biochemistry, Biology or Molecular Medicine of Ulm Universaity or any cooperating facility.

On request, it can be performed in an institute outside Ulm University.

Workload 450 hours

Assessment This module will be examined by the professor responsible for the selected project.

It will be graded the oral presentation of the progress report accounting for the methodogical approach and the scientific execution of the project.

Examination

Grading procedure

Basis for

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Module Master’s Thesis

Code 80000


ECTS credits 30

Credit hours 30

Duration 1 semester

Cycle Each semester


Lecturer All the professors in the selected Institute


Biophysics M.Sc., 4th Semester

Formal prerequisites Successful completion of the Biophysics compulsory modules, the adaptation modules, at least one module of the Specialisation area and at least one of the research projects (§15 FSPO).



have learned to integrate in a research team

are able to investigate a topic in the current research in physics independently and according to the rules of good scientific practice, and to develop their own approach

can prove and document their findings on scientific principles

are able to motivate their solutions and defend their thesis in a scientific discussion

Syllabus Execution of a theoretical or experimental research project

Evaluation of the obtained results

Discussion of the results in the context of the relative literature

Documentation of the research project

Literature


Research project to be carried on in either the department of Physics, Chemistry, Biology or Molecular Medicine of Ulm Universaity or any cooperating facility.

On request, it can be performed in an institute outside Ulm University.

Workload 900 hours

Assessment It will be graded the written thesis accounting for the methodogical approach and the scientific execution of the project.

Examination 88888 Master’s Thesis

Grading procedure The module grade is the grade for the Master’s thesis.

Basis for

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