Mental Health Crisis in the Wake of Covid-19STRATEGIES TO HELP EMPLOYEES COPE AND EXCEL

Louis Gagnon CEO, Total Brain

Mollie LombardiAnalyst, Human Capital Strategies

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LOUIS GAGNONCEO, Total Brain

MOLLIE LOMBARDIFounder, m.Research

SPEAKERS

There’s a Crisis Out There

U.S. workers currently at risk

52% 20% U.S. workers suffer from a mental condition

Brains are impaired

72% =

We Don’t Live at Our Full Capacity

Total Brain Helps Individuals

Improvetheir brain’s capacity

Manage their mental health risk

Improve health outcomes & reduce healthcare costs

Total Brain Helps Organizations

Improve productivity

Total Brain (TTB) ModelWhat is it?

Why does it matter?

Mental Health IndexU.S. Worker Edition

TTB App DemoIndividuals’ Experience

App DemoOrganizations’

Experience

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Agenda

Mental Health = Brain Capacities

All Capacities Are Constantly Impaired

By Fight-Flight Response AND/OR Sub/Clinical ConditionsThemselves driven by Uncontrollable Life Events (e.g.: COVID)

totalbrain.com/mentalhealthindex

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General Anxiety Disorder

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Depressive Disorder

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PTSD

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Social Anxiety Disorder

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Addiction

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Sleep Apnea

Risk of Mental Conditions Since Feb 2020

↑ 91% ↑ 163% ↑ 73%

↑ 55% ↑ 25% 0%

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Emotional Awareness

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Non-Conscious Negativity Bias

Emotional Capacities Since Feb 2020

0% ↑ 7%

• How we read emotional cues in others

• Drives relationships and trust

• How negatively biased we are given our past experiences

• Drives flexibility and creativity

Feeling Control Capacities Since Feb 2020

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Stress

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Anxiety

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Depressed Mood

↑ 47%↑ 28% ↑ 64%

• How much of a threat we perceive

• Drives performance… or burn-out

• How fearful we are vs. the future

• Drives our aversion to risk

• How negative and hopeless we feel

• Drives our bias for action

Cognitive Capacities Since Feb 2020

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Memory

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Focus

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Planning

↓ 8%0% -32%

• How much we remember

• Drives thinking and non-conscious bias

• How much we complete tasks

• Drives task completion

• How we make decisions

• Drives strategy

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Social Connectivity

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Resilience

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Conscious Negativity

Self-Control Capacities Since Feb 2020

↑ 23%↑ 3% ↓ 4%

• How much we connect to others

• Drives collaboration

• How much we bounce back from stress

• Drives business stamina

• How negative we consciously are

• Drives collaboration

What can we do?

Total Brain AppSELF-MONITOR AND SELF-CARE• 12 Brain Capacities (neuroscience)• Fight-Flight Response (bio-feedback)• 7 Mental Conditions (health screens)

We do not control life events but we do control how aware we are and how we react to life

Compare 12 capacitiesstrengths/weaknesses

Emotional awareness example task

Cognition (planning) example task

Self-Monitor CapacitiesReview highest and lowest capacities with percentile rankings (same age,

gender, edu)

Self-Care for CapacitiesBreathing exercises to balance emotions and

find calm focus

Daily feed prompts users with personalized content and exercise

regimen

Brain training exercises to improve positivity; shuts off

fight/flightRecommendations provided but users can always choose

Self-Monitor for Brain State

Measure HRV and compare vs norm and personal baseline; recommend actions

Measure Heart Rate Variability (HRV) with camera technology

Measure continuous HRV with proprietary band(Coming late 2020)

Self-Care for Brain State

Breathe at 6 BPM for 3 minutes to shut off your fight/flight system and feel calm and flexible

Mental ConditionsMonitor, Screen & Refer

Standardized screening questions

When at-risk: validation of symptoms

by users

Stress: DASSDepression: PHQ2/9Anxiety: GAD 2/7ADHD: Internal ADHD testAddiction: CAGE-AIDPTSD: VA PTSD TestSocial Phobia: DSM-IV Sleep Apnea: 1995 Maslin Sleep

Scientifically Validated 70–80% accurate

Health referrals when appropriate

(user-driven)

Aggregate Workforce AnalyticsVALUABLE DATA FOR EMPLOYERS

Total Brain Helps Businesses• Visualize corporate strengths, weaknesses and risks• Benchmark vs. norms and national index• Get custom analytics by office locations, departments, SBUs• Manage organizational change

Free Support for Employees

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Free Whitepaper: Available for free to help you and your employees understand how to mitigate the impact of COVID-19 on their mental health

Free 3-Month Corporate Subscription to Total Brain: Offer your employees free access to the Total Brain platform, available on desktop or mobile, to help them during this difficult time

1 2

Visit: info.totalbrain.com/covid-19-corporate

Q & A

Appendix

1. Implementation2. Scientific Basis3. Total Brain for Other Market Verticals 4. Total Brain as a Platform5. References6. Disclaimer

How Does TTB Get ImplementedComplete support throughout the program lifecycle

Customized reporting and analysis

Regular data reviews with scientific analysis and recommendations

Population Analytics

Dedicated account management support to enable ongoing engagement

User specific and population programs

Ongoing Engagement

Personalized care recommendations

In app referral to support services

Self care within the app or other application

Care Recommendations

Guided user assessment

Deep explanation of results

User Assessment

Integration into any member experience and engagement platforms

Onboarding enablement for any communication channel

User Onboarding

Neuroscience-Based Measurement

Capacities1,317 norms - peer regression modelingPractice effect neutralReliable and validated

1. Internal consistency2. Test-retest reliability3. Across site reliability4. Face validity with world experts5. Content validity 6. Concurrent validity 7. Convergent & construct validity

SymptomsAll screening questions use well-known, validated tests (70-80% accurate) like PHQ2/9, GAD 2/7, Internal ADHD test, CAGE-AID, DASS, VA PTSD Test, DSM-IV Social Phobia, 1995 Maslin Sleep

Measurements

Neuroscience-Based Measurement

Powerful DatabasePowered by the largest standardized neuroscientific database in the world with more than 1.3M standardized data sets (tasks, questions, EEG, MRIs, GWAS)

Data Sources Include200 brain studies at Harvard, NYU, MIT, Stanford, Oxford, Cambridge, etc. that generated 300 publications (licensing)

20 clinical trials of psychiatric drugs (licensing)

2 clinical trials predicting drug effectiveness for Depression and ADHD - (proprietary)

780K+ individual brain assessments/brain trainings through employers, consumer groups and clinics (proprietary)

Benchmarks & Insights

Neuroscience-Based Support ToolsSelf-Care Recommendations

CapacitiesWe use published data on which exercises affect which capacities

Neuroscience-Based Support ToolsSelf-Care Recommendations

SymptomsWe know which conditions affect which brain capacities by how much (avg.)

Mental Conditions Core Deficit 3 Top Capacity Deficits Created by Conditions

Addiction Craving Self Control, Planning, Resilience

Depression Negativity Conscious Negativity Bias, Non-Conscious Negativity Bias, Depressed Mood

Anxiety Fight/Flight Anxiety Control, Stress Control, Social Connectivity

ADHD Task Completion Focus, Controlled Attention, Memory

PTSD Intrusive Thoughts Anxiety Control, Conscious Negativity Bias, Resilience

Social Phobia Judgement Anxiety Control, Emotion Awareness, Social Connectivity

Sleep Fatigue Focus, Stress Control, Resilience

Go-to-Market Verticals, Top Clients, Biz Models

Patients• via Clinics• Insurance reimbursements

Employees• via HR departments • Price per employee or per user

Consumers• via B2C Affinity Groups• Tiered user-based or annual

license fee

Health seekers

Populationsover 50 years old

Populations in transition

Mental health seekers

Total Brain PlatformScalable technology set-up to address the needs of each vertical

B2C AffinityModular Total Brain platform services for configurable integration of any service or variation into a third-party experience

B2B CorporateCore Total Brain experience utilizing TB app and core assessment, screening, training services

ClinicalCore Total Brain experience utilizing TB app and core assessment, expanded screening, training services

Capacity Scoring

Screening Results

Training Scoring Usage TrendingResults

SharingRecommenda-

tions Notifications

Total Brain Web(Consumer/Clinical)

Total Brain Mobile(Consumer/Clinical)

Total Brain Services(Consumer/Clinical)

Total Brain Clinician Portal (Clinical)

User Experience

Data

Total Brain Platform Modules

ContentExercisesAssessment

FeelingStress ControlAnxiety Control

Depressive Mood Control

EmotionEmotion Awareness

Negativity BiasDefault Emotion

CognitionMemoryFocus

Planning

Self-ControlSocial Connectivity

ResilienceConscious Bias

Brain Training

PositivityFocus

MemoryResilience

Stress

Mind TrainingBreathingMeditation

Brain ImpactExplanations

Life ImpactPerspectives

Video

Audio(coming)

Text(coming)

Books(coming)

Health Partners (coming)

ScreeningLite Corporate / Consumer & Deep Clinical Versions

Depression

Anxiety

PTSD

Addiction

ADHD

Sleep Apnea

Social Anxiety

References

1. Based on a Total Brain internal, week over week user assessment data. Population studied: Representative sample of TTB population; n: 500-1,000 users per week; Statistically controlled

2. Based on example of large self-insured client program implementing TTB best practices – assessment 100% optional – NO HRA incentive

3. Based on Total Brain Internal data, n = 12,000. 61% of US employees screen at-risk of having one of 7 mental conditions.

4. Among those flagged as at risk for depression or anxiety, a 28% improvement in anxiety levels was found for those who completed 2 or more hours of training.

5. Among Total Brain users who completed 2 or more hours of training, a 39% improvement in depressed mood was found

6. Among Total Brain users who completed 2 or more hours of training, a 40% improvement in addiction symptoms was found

7. Improvements in brain performance correlated with average of three hours of training. 2017/2018 blended average internal book of business data; N = 11,116; Users who assessed + trained at least twice

8. Based on example of large self-insured client program; Data includes employees who have taken a follow-up assessment n=2760 in 2019; Trending/monitoring did not exist as a feature during that period

Disclaimer

This presentation is issued by Total Brain (ASX: TTB) (“Total Brain”, “the Company" or “we”) to you, is to be held confidentially by you and may not be shared by you with third parties. This presentation is general background information about the Company’s activities current as at the date of this presentation. The information is given in summary form and does not purport to be complete. This presentation is not an offer to sell, or any sale, of securities. Any offer and sale of securities would be done only pursuant to a written agreement between Total Brain and its investors.

Total Brain has made every effort to ensure that the information in this presentation is accurate. However, its accuracy, reliability or completeness cannot be assured. To the maximum extent permitted by law, we and our associates, respective officers, employees and agents, disclaim any liability for any error or omission or for any loss suffered as a result of others acting on the basis of the information contained in this document.

In particular this presentation includes forward looking statements (e.g. phrases with “will” “may”, “would”, “anticipate”, “expect” and other statements about future events, results or outcomes) regarding our belief, intent or expectations with respect to the Company’s businesses, market conditions and/or results of operations, and while our management believes reasonable assumptions have been made, the Company’s actual results may vary in a material and adverse manner,

nothing herein is a guarantee of future performance and you are cautioned not to place undue reliance on such statements.

Except to the extent required by law, the Company has no intention to update or revise forward-looking statements, or to publish prospective financial information in the future, regardless of whether new information, future events or any other factors affect the information contained in this presentation.

Any investment in the Company is subject to various risks, including but not limited to, our technology and science not meeting current expectations, intellectual property challenges, competition in the market, insufficient customer acquisition, legal and regulatory limitations in certain jurisdictions, privacy issues, among others.

Information in this presentation, including financial information, should not be considered as legal, financial or tax advice or a recommendation to investors or potential investors in relation to holding, purchasing or selling securities. Before acting on any information you should consider the appropriateness of the information having regard to these matters, any relevant offer document and in particular, you should seek your own independent financial, legal and tax advice.