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For personal use. Only reproduce with permission from The Lancet Publishing Group. Cannabis Jonathon Green Pavilion Books, 2002 £20, 256 pp ISBN 1 86205 479 7 “Why would a neurology journal want to review yet another book on cannabis?”, I asked myself, despite the acadenic- grey bound volume, boldly emblazoned CANNABIS in gold, and containing both enticing images and entrancing tidbits of cannabis culture, hashish history, and marijuana medicine (not forgetting the pot policy and reefer recipes). The ultimate coffee-table cannabis text. “Pass the brown sugar, thanks.” But if it were coffee-time and Cannabis was on the table, which neurologists would try it? Fascinating to many would be the decade-long voyage of discovery into our endogenous canna- binoid system. But Jonathon Green only briefly hits on anandamide, the brain’s “bliss molecule”, and the science of cannabinoids, in sparse details spread throughout the book. What he does offer is a vivid account of the historical and current uses of the plant and its products, including a helpful A-to-Z list of proposed medicinal benefits. Though clearly Cannabis was never intended for academics, I could imagine many neurologists taking a peek or two, being among the specialists most likely to encounter people using the drug therapeutically—for spasms, insomnia, multiple sclerosis, etc. The claims of benefits derived from the plant or its constituents has placed neurologists in the invidious position of being aware of a potential tool for palliation that is illegal, and in the middle of a legal and political debate about the place for the drug’s remedicalisation based on a science that hasn’t caught up yet. As Green suggests, use of cannabis and its extracts has perhaps never been higher, though he does not ask why. Are we re-evaluating its usefulness or is prohibition failing? Perhaps modern life means people need more analgesics and anaesthetics to get through the daily grind. Or an evolutionary argument I heard suggests that the plant would continue to adapt for human use, exploiting its niche as fibre, therapy, and intoxicant, to ensure further cultivation. But maybe that’s just the dope talking. Like other aspects of the book, Green’s treatment of wider issues is superficial, but he does admit he partakes regularly (though not with tobacco, anymore). Another cup? How many readers lost interest when they realised the author is a self-confessed “midnight toker” (Green, I mean, although there was this one time as a reckless preclinical student in India . . .)? And how many are reading on, wondering if Cannabis could give them or their waiting rooms more street cred? Although the book contains too little on the potential harms of some methods of administration to make Cannabis “safe” to leave in most waiting rooms, to my mind, Green does relay a valid view of global cannabis culture, rendering the personal experience of intoxication through the testimony of great thinkers, reputed artists, and historians who have attempted to capture the essence. Phew! Light the incense! No need then for me to recount my quarter. But I didn’t inhale. And I do believe every clinician needs to be acquainted with the basic uses and misuses of all common drugs, including weeds, but the reality is that they aren’t. For example, the story I heard first-hand of a young lad who— when stopped incidentally by the police—emptied his pockets to discover, among the loose change and fluff, a large piece of hash (cannabis resin). Which he promptly ate (I guess the theory goes that possession is illegal in the UK whereas ingestion is not). What was most surprising, he said, was the reaction of the casualty doctor when the officers took him to hospital. “She didn’t seem to know anything about it [cannabis] or what it would do to me. She kept asking me what I had taken”, he recalled. “I was just lying there, fighting to keep awake, so paranoid that if I fell asleep they would try to pump my stomach.” I hope most neurologists are more seasoned, through patients’, if not, personal experience. Though chance would predict that a few neurologists are or have been secret “tokers”, since cannabis use continues to be widespread among all groups, even otherwise upstanding professionals. Tabloid reports of a “roach” (from “cockroach”, not an insect, but a name for the end of a ‘joint’—La Cucuracha was an infamous Mexican marijuana-smoking cockroach) in the UK government Cabinet offices may attest that dopeheads abound at the highest levels. For potheads and spliff-junkies, Green’s book seems a good bible, giving the lowdown on making a “bong”, how to “back-roll” to use less paper, tips to grow-your-own, and classic recipes for hash brownies and bhang lassi. Which reminds me of my own personal research . . . “Another coffee? Yes, why not. I forgot what I was telling you.” Kelly Morris On page 291 of this issue, David Baker and coauthors review the therapeutic potential of cannabinoids and the cannabinoid system. THE LANCET Neurology Vol 2 May 2003 http://neurology.thelancet.com 319 Media watch

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For personal use. Only reproduce with permission from The Lancet Publishing Group.

CannabisJonathon Green Pavilion Books, 2002£20, 256 ppISBN 1 86205 479 7

“Why would a neurology journal want to review yet anotherbook on cannabis?”, I asked myself, despite the acadenic-grey bound volume, boldly emblazoned CANNABIS ingold, and containing both enticing images and entrancingtidbits of cannabis culture, hashish history, and marijuanamedicine (not forgetting the pot policy and reefer recipes).The ultimate coffee-table cannabis text. “Pass the brownsugar, thanks.”

But if it were coffee-time and Cannabis was on the table,which neurologists would try it?Fascinating to many would be thedecade-long voyage of discoveryinto our endogenous canna-binoid system. But JonathonGreen only briefly hits onanandamide, the brain’s “blissmolecule”, and the science ofcannabinoids, in sparse detailsspread throughout the book.What he does offer is a vividaccount of the historical andcurrent uses of the plant and itsproducts, including a helpful A-to-Z list of proposed medicinalbenefits.

Though clearly Cannabis wasnever intended for academics, Icould imagine many neurologiststaking a peek or two, beingamong the specialists most likelyto encounter people using thedrug therapeutically—for spasms,insomnia, multiple sclerosis, etc.The claims of benefits derived from the plant or itsconstituents has placed neurologists in the invidiousposition of being aware of a potential tool for palliation thatis illegal, and in the middle of a legal and political debateabout the place for the drug’s remedicalisation based on ascience that hasn’t caught up yet.

As Green suggests, use of cannabis and its extracts hasperhaps never been higher, though he does not ask why. Arewe re-evaluating its usefulness or is prohibition failing?Perhaps modern life means people need more analgesicsand anaesthetics to get through the daily grind. Or anevolutionary argument I heard suggests that the plantwould continue to adapt for human use, exploiting its nicheas fibre, therapy, and intoxicant, to ensure furthercultivation. But maybe that’s just the dope talking. Likeother aspects of the book, Green’s treatment of wider issuesis superficial, but he does admit he partakes regularly(though not with tobacco, anymore).

Another cup? How many readers lost interest when theyrealised the author is a self-confessed “midnight toker”

(Green, I mean, although there was this one time as areckless preclinical student in India . . .)? And how many arereading on, wondering if Cannabis could give them or theirwaiting rooms more street cred? Although the bookcontains too little on the potential harms of some methodsof administration to make Cannabis “safe” to leave in mostwaiting rooms, to my mind, Green does relay a valid view ofglobal cannabis culture, rendering the personal experienceof intoxication through the testimony of great thinkers,reputed artists, and historians who have attempted tocapture the essence. Phew! Light the incense!

No need then for me to recount my quarter. But I didn’tinhale. And I do believe every clinician needs to beacquainted with the basic uses and misuses of all commondrugs, including weeds, but the reality is that they aren’t.

For example, the story I heardfirst-hand of a young lad who—when stopped incidentally bythe police—emptied hispockets to discover, among theloose change and fluff, a largepiece of hash (cannabis resin).Which he promptly ate (I guessthe theory goes that possessionis illegal in the UK whereasingestion is not). What wasmost surprising, he said, wasthe reaction of the casualtydoctor when the officers tookhim to hospital. “She didn’tseem to know anything about it[cannabis] or what it would doto me. She kept asking me whatI had taken”, he recalled. “I wasjust lying there, fighting to keepawake, so paranoid that if I fellasleep they would try to pumpmy stomach.”

I hope most neurologistsare more seasoned, through patients’, if not, personalexperience. Though chance would predict that a fewneurologists are or have been secret “tokers”, since cannabisuse continues to be widespread among all groups, evenotherwise upstanding professionals. Tabloid reports of a“roach” (from “cockroach”, not an insect, but a name forthe end of a ‘joint’—La Cucuracha was an infamousMexican marijuana-smoking cockroach) in the UKgovernment Cabinet offices may attest that dopeheadsabound at the highest levels.

For potheads and spliff-junkies, Green’s book seems agood bible, giving the lowdown on making a “bong”, howto “back-roll” to use less paper, tips to grow-your-own, andclassic recipes for hash brownies and bhang lassi. Whichreminds me of my own personal research . . . “Anothercoffee? Yes, why not. I forgot what I was telling you.”Kelly Morris

On page 291 of this issue, David Baker and coauthors review thetherapeutic potential of cannabinoids and the cannabinoid system.

THE LANCET Neurology Vol 2 May 2003 http://neurology.thelancet.com 319

Media watch