maternal mortality in jordan

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    Maternal Mortality in Jordan

    2007-2008

    Professor Zouhair Amarin

    Jordan University of Science and Technology

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    Worldwide, childbearing carries a major

    risk to the life of women

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    http://images.google.jo/imgres?imgurl=http://www.marefa.org/images/thumb/2/2f/Small_Flag_of_the_United_Nations_ZP.svg/488px-Small_Flag_of_the_United_Nations_ZP.svg.png&imgrefurl=http://www.marefa.org/index.php/%25D8%25B5%25D9%2588%25D8%25B1%25D8%25A9:Small_Flag_of_the_United_Nations_ZP.svg&usg=__LXQ_woFmXQp2TeUEoOTNhD-rkT8=&h=488&w=488&sz=91&hl=ar&start=3&tbnid=YSDhti4CK7KEJM:&tbnh=130&tbnw=130&prev=/images%3Fq%3Dunited%2Bnations%26gbv%3D2%26hl%3Dar%26safe%3Dactive
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    http://en.wikipedia.org/wiki/File:The_United_Nations_Building.jpg
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    Measures of maternal mortality

    rateMaternal mortality

    ratioMaternal mortality

    Lifetime risk of maternal death

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    are often used interchangeablyRate and Ratio

    useddenominatorIt is essential to specify the

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    rateMaternal mortality

    Is the number of maternal deaths in a given period

    women of reproductive age100 000per

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    ratioMaternal mortality

    Is the number of maternal deaths during a

    duringlive births100 000given year per

    the same period

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    The Millennium Development Goals (MDGs

    are eight international development goals

    192 United Nations member states and 23

    international organizations have agreed to

    achieve those goals by the year 2015

    http://en.wikipedia.org/wiki/International_developmenthttp://en.wikipedia.org/wiki/United_Nationshttp://en.wikipedia.org/wiki/United_Nations_member_stateshttp://en.wikipedia.org/wiki/International_organizationshttp://en.wikipedia.org/wiki/International_organizationshttp://en.wikipedia.org/wiki/United_Nations_member_stateshttp://en.wikipedia.org/wiki/United_Nationshttp://en.wikipedia.org/wiki/International_development
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    Reducing maternal mortality by three quarters

    between 1990 and 2015 is a specific part of Goal 5

    (Improving Maternal Health) of the eight MDGs

    http://en.wikipedia.org/wiki/Millenium_Development_Goalshttp://en.wikipedia.org/wiki/Millenium_Development_Goals
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    At global level, maternal mortality

    has decreased less than 1% annually

    between 1990 and 2005

    This is far below the 5.5% annual

    decline, which is necessary to achievethe fifth MDG

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    WHO UNICEF and UNFPA 2003 MMR

    The world average 400

    Developed regions 20

    Developing regions 440

    http://en.wikipedia.org/wiki/World_Health_Organizationhttp://en.wikipedia.org/wiki/UNICEFhttp://en.wikipedia.org/wiki/UNFPAhttp://en.wikipedia.org/wiki/UNFPAhttp://en.wikipedia.org/wiki/UNICEFhttp://en.wikipedia.org/wiki/World_Health_Organization
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    Approaches for measuring maternal mortality

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    Civil Registration Systems

    Routine recording of deaths is not complete

    The womans pregnancy status may not beknown and the death would not be reported

    as a maternal death

    Medical certification of death is deficient,

    accurate attribution of deaths as maternal

    death is difficult

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    In the UK, the Confidential Enquiry into

    Maternal Deaths (20002002) identified 44%

    more maternal deaths than was reported in the

    routine Civil Registration System

    Studies have shown that the true number ofmaternal deaths could be almost 200% higher

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    In the absence of complete and accurate civil

    registration systems, MMRs are based upon:

    Household surveys

    Sisterhood methods

    Reproductive-age mortality studies (RAMOS)

    Verbal autopsies

    Censuses

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    2007 - 2008

    Study

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    Objectives

    1. Determine maternal mortality ratio among Jordanian women

    2. Identify the direct and indirectcauses of maternal mortality

    3. Determine the extent to which maternal deaths arepreventable

    4. Assess hospital medical and vital records for completeness

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    Step 1

    Civil Registry, 1164 names were obtainedfor dead married women, 15-49 years of

    age

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    Step 2

    From the MOH, 848 names were obtained

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    Step 3

    Both lists were pooled to contain only marriedwomen in the age group 15-49 years

    1177names

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    Step 4

    229 names from hospital registries

    1177 + 229 = 1406 dead women of

    reproductive age

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    All hospitals and forensic departments werevisited to search for maternal deaths

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    112

    pregnancy related maternal deaths

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    Number of maternal deaths, number of live births, total fertility

    rate, and measures of maternal mortality in 2007-2008

    76 deaths (60-95)

    Number of maternal deaths in 2007-

    2008 (95% CI)

    397588 live birthsNumber of live births

    3.6Total fertility rate in 2007

    19.1 (14.3-26.5)Maternal Mortality Ratio (95% CI)

    2.0Maternal Mortality Rate

    0.0007 (1 in 1428)

    Lifetime risk of maternal death (The

    probability that a 15-year-old female

    will die from a maternal cause)

    Sociodemographic and health characteristics of study population

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    Sociodemographic and health characteristics of study population

    (N=76)

    %nAge

    40.83115-29

    35.52730-39

    23.71840-49

    Region

    59.245Middle (62.3% of population)

    2519Northern (28.1% of population)

    15.812Southern (9.3% of population)

    Family size

    29.3172-3

    41.4244-6

    29.3177 (average family size 5.75)

    Income in Jordanian Dinar

    80.441350

    19.610>350

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    %nGravidity

    43.1281-332.3214-6

    24.6167

    Parity

    34.8230-1

    39.4262-4

    25.8175

    Gestational age24.01827

    22.71728-36

    53.34037

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    %nCauses of maternal deaths

    73.756Direct Causes

    25.019HaemorrhageUterine rupture (n=5)

    Uterine atony (n=5)

    Placental abruption (n=3)

    DIC (n=4)

    Ruptured ectopic pregnancy (n=2)

    23.718Thrombosis and thromboembolism

    7.96Sepsis

    6.65Hypertensive disorders of pregnancy5.34Amniotic fluid embolism

    3.93Anesthesia

    1.31Hyperemesis gravidarum

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    %nCauses of maternal deaths

    26.320Indirect Causes

    10.58Cardiac disease

    7.96Diseases of the CNS

    CVA (n=4)Epilepsy (n=2)

    5.24Infectious diseases

    Hepatobiliary peritonitis (n=2)

    Pancreatic perotonitis (n=1)

    Pulmonary infection (n=1)

    1.31Chronic anemia

    1.31Renal failure

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    75% of cardiac deaths were associated with some degree of substandard care

    Avoidable deaths

    %nVariable

    5441Avoidable deaths

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    Antenatal care (N = 54*)

    %nAntenatal attendance

    83.345Received antenatal care

    16.79No antenatal care

    10054Total

    *22 women had no details of ANC

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    Antenatal care (N = 45)

    %nBooking and # visits

    91

    9100

    41

    445

    1st trimester booking visit

    2nd or 3rd trimester bookingTotal

    33.3

    66.7100

    15

    3045

    Number of visits

    1-3

    4Total

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    Frequency distribution of maternal deaths by period of pregnancy, type of

    hospital and autopsy status (N=76)

    %nPeriod of pregnancy

    36.8

    6.6

    56.6

    28

    5

    43

    During pregnancy

    Intrapartum

    Postpartum

    Type of hospital

    17.113Dead on arrival2.62Maternity

    46.135Peripheral

    34.226Referral

    Autopsy status17.113Dead on arrival - Autopsy

    11.89Hospital death - Autopsy

    3.93Brought-in dead - No Autopsy

    67.151Hospital death - No Autopsy

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    Frequency distribution of maternal deaths by delivery (N=76)

    TotalType of delivery

    24 (31.5 %)No delivery5 (6.5 %)Abortion

    15 (19.7 %)Spontaneous vaginal

    1 (1.3 %)Induced vaginal

    1 (1.3 %)Ventouse

    3 (3.9 %)Forceps

    0 (0.0 %)Vaginal breech

    27 (35.5 %)Caesarean section

    20 (26.3 %)Emergency

    5 (6.5 %)Elective

    1 (1.3 %)Perimortem

    1 ( 1.3 %)Postmortem

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    Frequency distribution by contraceptive practices

    %nEver use of contraception

    29.415Yes

    70.636No

    Planned pregnancy

    51.339Yes

    Of all 76 maternal deaths, the details of family

    planning were not available for 25 (32.9%) women

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    Delays

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    Delays and standards of care

    %n

    4.03Transport delay

    55.342Delay in seeking care

    48.737Lack of prompt care

    52.640Substandard management

    5.34Suboptimal facilities

    F di ib i f id l d i id l d h b

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    Frequency distribution of accidental and incidental deaths by cause

    nCause of death

    11Road traffic accident

    4CO poisoning3Lymphoma or Leukemia

    2Homicide

    1Burn

    2Electric shock

    1Meningitis

    1Pancreatic cancer

    1Breast cancer

    1Ruptured aneurism

    1Colon cancer

    2Bowel obstruction

    3Cardio-vascular accident

    1Dog bite

    1Fall

    1Drowning

    36Total

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    Out of 72 files on maternal deaths (4 files could not be

    located), only 12 (16.6%) were well structured and had

    complete details about events in their respective hospitals

    Substandard quality was evident in all other medical case

    notes that were reviewed

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    2007-20081995/6

    19.141.4MMR

    HaemorrhageHypertensionDirect 1

    Thrombotic eventsHaemorrhageDirect 2

    SepsisThrombotic eventsDirect 3

    CardiacCardiacIndirect 1

    CNS eventsMalignancyIndirect 2

    Infectious diseasesDiabetesIndirect 3

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    This report should reassure the public that maternal deaths in

    Jordan are rare and declining. Overall, 76 women had a

    maternal death out of the 397588 mothers who gave live birthduring 2007-2008

    The MMR for both direct and indirect causes of death showed a

    remarkable decrease as compared with the last Report of 1995-

    1996

    A reduction of 53.9% achieved in 12 years (4.5% annual

    reduction) goes well with the 75% reduction as recommended

    by the MDG 5

    At global level, maternal mortality had decreased at an average

    of < 1% annually between 1990 and 2005. This is far below the

    5.5% annual decline recommended by the MDG 5

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    RECOMMENDATIONS

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    General

    Recognition of maternal health as a priority issue

    Reallocation of human and financial resources to the

    relevant interventions

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    Scale up the implementation of the strategies and plans ofaction related to Making Pregnancy Safer

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    Upgrade recording and reporting systems

    Develop national surveillance systems to identify

    epidemiological patterns and maternal mortality trends

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    Implementation of community-based interventions related to

    maternal health

    Early recognition of the danger signs of sickness and also on

    preventive measures to promote maternal health

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    Introduce maternal health guidelines into the teachingcurricula of medical and paramedical schools

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    Haemorrhage

    A forum of experts at a national level is recommended to

    develop a multidisciplinary massive haemorrhage protocol

    that should be updated and rehearsed regularly in conjunction

    with blood banks

    All grades of staff should participate in drills on site and

    consultant haematologists should be involved

    Women at high risk of bleeding should be delivered in centres

    with facilities for blood transfusion and ICU

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    Thromboembolism

    Acute symptoms suggestive of thromboembolism in known

    high-risk women are an emergency and anticoagulation may be

    indicated before the diagnosis is clear

    Attention should be paid to the up-to-date guidance on dosages

    A thrombophilic risk profile protocol should be developed and

    implemented in all maternity hospitals

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    Sepsis

    Hospitals should have an antibiotic policy for cases of sepsis

    to control infection and prevent the development of DIC and

    organ failure

    Advice from a microbiologist must be sought early to ensure

    appropriate antibiotic therapy

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    Cardiac disease

    Women with known cardiac disease should receive pre-

    pregnancy counseling

    All medical and nursing staff should be trained in basic,

    intermediate and advanced life support

    Emergency drills for maternal resuscitation should be

    regularly practiced, and should include the identification ofthe equipment required

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    Preconception counseling and antenatal care

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    Health Education

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    Communication and collaboration

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    Continuous professional development

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    Policies and protocols

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    Accreditation

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    Multidisciplinary support

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    Documentation

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    Death notification

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    Finally

    the act of getting pregnant should not be a death

    sentence

    BBC reporter on maternal mortality in Malawi, where 1in 10 dies during childbirth

    26th October 2009

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    Thank you