marketing and sales roles in the pharmaceutical industry
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M arketing and Sales Rolesin the Pharmaceuti cal I ndustry
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MARKETING
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The Marketing Concept - Key Principles
It is easier to change the products and services of the individualmanufacturer to fit the needs of the market than it is to convince theentire market to use the products and services as the individualmanufacturer prefers them You can have any color car you want as long as its black
Henry Ford
All the resources of the firm should be organized into a total systemaimed at meeting the needs of the consumer
The role of marketing is to influence or direct activities from themanufacturer to the patient: The right products In the right quantity At the right place
For the right price At the right time
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Marketing as an Actualizing Process
Markets can be viewed as gaps that separate parties interested in an exchange Marketing removes the gaps between the parties through various actualization
processes
Source: McInnis; A Conceptual Approach to Marketing
MARKETSEPARATORS
TIME
SPACE
VALUE
OWNERSHIP
QUANTITY
ASSORTMENT
EXCHANGE FLOWS
PRODUCT FLOW:toward the consumer
INFORMATION FLOW:both ways
PAYMENT FLOW:toward the provider
USE RIGHT:toward the consumer
MARKETING ACTIVITIES
Assembly, transportation storage,packaging, grading
Advertising, personal selling, publicity,labeling, sales promotions, marketingresearch, consumer complaints, drugeducation programs
Credit and cash payments
Purchasing and selling, pricing, posttransactional rights
PRODUCERS
CONSUMERS
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ITs Role in the Actualizing Process
IT can assist marketing in closing the gaps that separate parties interested in anexchange
IT can make some of the gaps irrelevant (e.g., space and time)
Source: McInnis; A Conceptual Approach to Marketing
MARKETSEPARATORS
TIME
SPACE
VALUE
OWNERSHIP
QUANTITY
ASSORTMENT
IT
Connectivity across geographically dispersedregions
24 x 7 Availability
Enabling information access
Enhancing personalization
Right use Right amount Right need
Increasing the number of available options
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Unique Aspects of PharmaceuticalMarketing and Sales Influence of non-purchasers on the purchasing habits of the consumer
Veto/authorization power of physicians consumers need anauthorized document to purchase a prescription drug
Importance of the disease to identifying and classifying markets
Professional licensing required to stock and sell pharmaceutical products
Records of every transaction are kept that are specific to: Patient Physician Product
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Definitions
Market Research: Determination and assessment of qualitative and quantitative
dimensions of a market
Market ing Research: Analysis of the effects of various marketing activities of a
company or its competitors
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Market Research
Environmental scanning: Physicians Pharmacists Pharmacies Hospitals
Data gathering and analysis Influence of unique aspects of the pharmaceutical market on market
research: Known list of entities Knowledge-based decisions
Similarities in education and thinking (professionalization) Availability of records for transactional activity
Significant use of outside vendors for market research Syndicated services Custom services
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Questions Answered by Market Research
Strategic Level: What diseases or product areas should be considered for long-term
investment? Short-term? Market size or potential?
Availability and utilization of therapies? Next logical steps in therapy? Potential market segments to be exploited:
Disease conditions (e.g., migraine sufferers) Dosing preferences (inhalants vs. injections vs. patches)
Prevalence of disorder? Shared conditions? Potential development partners? Potential acquisitions?
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Questions Answered by Market Research
Clinical trial Planning: Seasonality Regionality Specialty
Premarketing Planning: What physician specialties are important in a given therapy or diagnosis? What patient characteristics are important? Who are our competitors in this market?
How do our competitors promote their product? Are there unsatisfied portions of the market? How do physicians perceive a proposed product?
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Questions Answered by Market Research
Post-marketing Monitoring: Adverse events Product sales Patient information (medical history)
This can be critical inproduct defensesituations!Example : Pfizersdefense of Viagrawhen suits were filedalleging an increased
risk of stroke.
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Types of Market Research
PeriodicSurveys
Retail PharmacyPurchases
HospitalPurchases
WarehouseWithdrawals
PromotionalMedia
PhysicianPanels
Retail PharmacyPrescriptions
Retail PharmacySales
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Types of Market Research
PeriodicSurveys
Retail PharmacyPurchases
Measures theinflow of productsfrom themanufacturer to the
pharmacy OTC Prescription drugs Indirect (through
wholesalers) Direct purchases
from manufacturers
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Types of Market Research
PeriodicSurveys
HospitalPurchases Measures the
inflow of productsfrom themanufacturer to thehospital
OTC Prescription drugs Indirect (through
wholesalers) Direct purchases
from manufacturersGrowth of pharmaceutical purchases byhospitals has greatly exceeded purchases frompharmacies on a proportional basis
In many communities, the hospital has become
more important in routine care
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Types of Market Research
PeriodicSurveys
WarehouseWithdrawals
Measures the outflow of products from thewarehouse to all
purchasers
OTC Prescription drugs)
Does not reflect direct purchases frommanufacturers
Provides ability to analyzesmall segments of themarketplace such as zipcode or territories
Can be valuable in dealing with questions ofindividual territory performance and potential ordifferent selling techniques
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Types of Market Research
PeriodicSurveys Retail Pharmacy
Prescriptions
Measures the outflow of prescription drugs fromthe pharmacy to consumers
Most sensitive indicator of
prescription product performance (factual)
Reflects mindset of prescribers and consumerdemand
Best indicator of marketingor promotional efforteffectiveness
Data available at nationaland sub-national levels
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Types of Market Research
PeriodicSurveys
PhysicianPanels
Specialized researchservices to identify patient
product usage alongspecific variables:
Diagnosis Patient characteristics Location of visit Drugs used Action desired from
drugs used
Tracking of new prescriptions over time andmonitors changes in doctor
prescribing habits
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Types of Market Research
PeriodicSurveys
Retail PharmacySales
Historically used for non- prescription pharmaceuticals
Data typically collected for
products of interest Collect unit and dollar
information at the packagesize level
Main use is to obtain prescription counts by
product Used for pricing analysis
and cross-tabulationanalysis using datawarehouses
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Types of Market Research
PeriodicSurveys
PromotionalMedia
Monitoring of detailingvisits to physicians bysales representatives
Monitoring of journaladvertising
Monitoring of direct mail
advertising Physician sampling
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Market Research Organizations
IMS Health Datamonitor Healthcare Consulting Frost.com Reuters Also check out:
Eyeforpharma.com FDA.gov Journal of the American Hospital Association AMA Drug Evaluations
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Market Research Industry Associations
EphMRA European Pharmaceutical ResearchAssociation (www.ephmra.org)
BHBIA British Healthcare Business IntelligenceAssociation (www.bhbia.org.uk)
PhRMA Pharmaceutical Research and ManufacturersAssociation (www.phrma.org)
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SALES
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Sales Roles Detailing
Face-to-face visits to physicians or purchasingmanagers (e.g., hospitals, HMOs) to present new
prescription drugs Influence prescribing habit
Increase current prescription usage Deliver samples Build relationships with doctors Get drug into a formulary; pull through
Sample Management Track delivery of prescription drug samples to
physicians or other purchasers
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Effective Detailing
Influences on Physician Prescribing Habits
Source: IBM Analysis
Side Effects
Drug deliverymethod
Cost of drug
EfficacyPotential drug-
druginteractions
Dosage
Payorformulary
status
Brand
Personalpreference
Patient request
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Detailings Value to the Physician
I like the good, tangibleinformation about a new drug
The samples determine what Iprescribe for the long term Samples are extremely valuable I value the relationships with them.
Overall, I am satisfied with theirservice
I rely on them to keep me aware of
whats happening in the drugindustry
I like their presence to break upmy stressed schedule
Everybody likes perks
Comments From PhysicianInterviews
Learn new drug information
Get drug samples
Connect with peers or physicianthought leaders
Receive the perks
Establish personal contact withthe drug company
Provide stress release
Value of Relationship withPharmaCos to Physicians
Source: IBM Analysis
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Detailing - Physician Concerns
20%Not enough samples
28%Not enough medical expertise
40%Take too much time
44%Too many from the same company
Inconvenient timing
Biased information
What are your top complaints about detailers?
Source: The Forrester Report: Pharmas Detailing Overhaul, February 2001 (IMS Health, Scott -Levin, Forrester Research, Inc); (Ziment/WebSurveyMD.com); IBM Analysis
I view them as the liaison but Idont take them at their word allthe time
I hate negative marketing. Thelack of objectivity is a big turnofffor me
If they keep coming back with thesame information, its a waste ofboth parties time
I appreciate the information, butthe reps can be pushy
The thing I dislike the most iswhen the rep doesnt appreciatethat I am busy and still tries topitch the drug to me
I dont believe that someone witha bachelors degree knows moreabout how a drug works than I do
Physician Comments
78%
47%
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Companies Are Experimentingwith e-Detailing
Source: IMS Health, iPhysicianNet website, Aptilon.com website, IBM Analysis
There have been promises made about the benefits of e-Detailing
Benefits to PhysiciansBenefits to PharmaCos
Cost-effective: an online sales session costsabout $110 on average, compared with about$200 for a field reps office visit
Cost effective: Increased contact time per visitallows for higher information content
Better control of detailing content: as a result,e-Detailing can be used as an efficient way totrain less-skilled sales reps
Capture relevant physician practice data: withthis information, Companies can identifypotential high prescribers that sales reps cantarget later
Counter detailing and off-the-label discussion:with e- Detailing, the companys medicalexperts can speak with physicians aboutcompeting drugs clinical trial flaws and off -the-label prescription, which is normally notallowed in a sales reps visit
Increased sales of under-marketed drugs
Allows physicians to see sales reps,gather information they deem important,and to have the flexibility and control todo it in their own schedule
Offers physicians a range of convenientinteractive channels
Provides timely updated druginformation
Provides simpler sample ordering anddelivery
Provides quality peer-to-peerdiscussions on a topic that interests aphysician.
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Sample Management
The pharmaceutical industry in America distributed$6.7 billion worth of samples to physicians in 1999 *
During a typical month, the average pharmaceuticalsales representative will visit 150 physicians,distribute thousands of packages of drug samples,obtain FDA required signatures on 150 sampledistribution forms and receive scores of new sample
cartons to their home-based office, and expend asmuch as 25% of their time tediously managing a paper-based process
* Source: IMS Health
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Sample Management andRegulatory Requirements
PDMA (Prescription Drug Marketing Act) Designed to minimize the threat to the public health
posed by prescription drug diversion and counterfeiting
Requires that samples distributed by pharmaceuticalrepresentatives be signed for and tracked to create audittrails
Helps to ensure that the correct physician receives thecorrect samples. If a pharmaceutical company is found
to be non-compliant, they could face significant penalties, fines, and possibly even prison terms
Source: FDA
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OTH ER M ARKETI NG& SAL ES TECH NI QUES
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Key Opinion Leader Management
Expert physicians -- often called "opinion leaders" or "thought leaders"-- play critical roles in driving pharmaceutical sales Participate in ongoing R&D Have privileged access to R&D information Company-sponsored featured speaking engagements at prestigious
conferences
Exchange ideas with other physicians regarding new products orindications or adverse events
Helps convince other doctors to prescribe new products and can makethe difference between a successful product launch and a majordisappointment
Program is actively integrated with marketing program: Physician recruitment (specialty, name recognition, etc.) Matching to appropriate R&D efforts Matching to appropriate marketing programs
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Medical Science Liaisons (MSLs)
Scientific professionals Pharmaceutical PhDs Pharmacists Physicians Nurses
Generally have more scientific knowledge than sales representatives Roles:
Support and expand sales representatives marketing of a product Be able to speak to the purchaser on a more scientific (peer) level; not on a
marketing level Will focus on clinical information
Focus on key opinion leaders Typically will only see more knowledgeable sales reps Organize symposia, conferences, focus groups, etc. Training and continuing education programs
May be involved in setting up Phase IV trials (post launch)