marketing and sales roles in the pharmaceutical industry

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    M arketing and Sales Rolesin the Pharmaceuti cal I ndustry

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    MARKETING

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    The Marketing Concept - Key Principles

    It is easier to change the products and services of the individualmanufacturer to fit the needs of the market than it is to convince theentire market to use the products and services as the individualmanufacturer prefers them You can have any color car you want as long as its black

    Henry Ford

    All the resources of the firm should be organized into a total systemaimed at meeting the needs of the consumer

    The role of marketing is to influence or direct activities from themanufacturer to the patient: The right products In the right quantity At the right place

    For the right price At the right time

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    Marketing as an Actualizing Process

    Markets can be viewed as gaps that separate parties interested in an exchange Marketing removes the gaps between the parties through various actualization

    processes

    Source: McInnis; A Conceptual Approach to Marketing

    MARKETSEPARATORS

    TIME

    SPACE

    VALUE

    OWNERSHIP

    QUANTITY

    ASSORTMENT

    EXCHANGE FLOWS

    PRODUCT FLOW:toward the consumer

    INFORMATION FLOW:both ways

    PAYMENT FLOW:toward the provider

    USE RIGHT:toward the consumer

    MARKETING ACTIVITIES

    Assembly, transportation storage,packaging, grading

    Advertising, personal selling, publicity,labeling, sales promotions, marketingresearch, consumer complaints, drugeducation programs

    Credit and cash payments

    Purchasing and selling, pricing, posttransactional rights

    PRODUCERS

    CONSUMERS

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    ITs Role in the Actualizing Process

    IT can assist marketing in closing the gaps that separate parties interested in anexchange

    IT can make some of the gaps irrelevant (e.g., space and time)

    Source: McInnis; A Conceptual Approach to Marketing

    MARKETSEPARATORS

    TIME

    SPACE

    VALUE

    OWNERSHIP

    QUANTITY

    ASSORTMENT

    IT

    Connectivity across geographically dispersedregions

    24 x 7 Availability

    Enabling information access

    Enhancing personalization

    Right use Right amount Right need

    Increasing the number of available options

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    Unique Aspects of PharmaceuticalMarketing and Sales Influence of non-purchasers on the purchasing habits of the consumer

    Veto/authorization power of physicians consumers need anauthorized document to purchase a prescription drug

    Importance of the disease to identifying and classifying markets

    Professional licensing required to stock and sell pharmaceutical products

    Records of every transaction are kept that are specific to: Patient Physician Product

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    Definitions

    Market Research: Determination and assessment of qualitative and quantitative

    dimensions of a market

    Market ing Research: Analysis of the effects of various marketing activities of a

    company or its competitors

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    Market Research

    Environmental scanning: Physicians Pharmacists Pharmacies Hospitals

    Data gathering and analysis Influence of unique aspects of the pharmaceutical market on market

    research: Known list of entities Knowledge-based decisions

    Similarities in education and thinking (professionalization) Availability of records for transactional activity

    Significant use of outside vendors for market research Syndicated services Custom services

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    Questions Answered by Market Research

    Strategic Level: What diseases or product areas should be considered for long-term

    investment? Short-term? Market size or potential?

    Availability and utilization of therapies? Next logical steps in therapy? Potential market segments to be exploited:

    Disease conditions (e.g., migraine sufferers) Dosing preferences (inhalants vs. injections vs. patches)

    Prevalence of disorder? Shared conditions? Potential development partners? Potential acquisitions?

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    Questions Answered by Market Research

    Clinical trial Planning: Seasonality Regionality Specialty

    Premarketing Planning: What physician specialties are important in a given therapy or diagnosis? What patient characteristics are important? Who are our competitors in this market?

    How do our competitors promote their product? Are there unsatisfied portions of the market? How do physicians perceive a proposed product?

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    Questions Answered by Market Research

    Post-marketing Monitoring: Adverse events Product sales Patient information (medical history)

    This can be critical inproduct defensesituations!Example : Pfizersdefense of Viagrawhen suits were filedalleging an increased

    risk of stroke.

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    Types of Market Research

    PeriodicSurveys

    Retail PharmacyPurchases

    HospitalPurchases

    WarehouseWithdrawals

    PromotionalMedia

    PhysicianPanels

    Retail PharmacyPrescriptions

    Retail PharmacySales

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    Types of Market Research

    PeriodicSurveys

    Retail PharmacyPurchases

    Measures theinflow of productsfrom themanufacturer to the

    pharmacy OTC Prescription drugs Indirect (through

    wholesalers) Direct purchases

    from manufacturers

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    Types of Market Research

    PeriodicSurveys

    HospitalPurchases Measures the

    inflow of productsfrom themanufacturer to thehospital

    OTC Prescription drugs Indirect (through

    wholesalers) Direct purchases

    from manufacturersGrowth of pharmaceutical purchases byhospitals has greatly exceeded purchases frompharmacies on a proportional basis

    In many communities, the hospital has become

    more important in routine care

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    Types of Market Research

    PeriodicSurveys

    WarehouseWithdrawals

    Measures the outflow of products from thewarehouse to all

    purchasers

    OTC Prescription drugs)

    Does not reflect direct purchases frommanufacturers

    Provides ability to analyzesmall segments of themarketplace such as zipcode or territories

    Can be valuable in dealing with questions ofindividual territory performance and potential ordifferent selling techniques

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    Types of Market Research

    PeriodicSurveys Retail Pharmacy

    Prescriptions

    Measures the outflow of prescription drugs fromthe pharmacy to consumers

    Most sensitive indicator of

    prescription product performance (factual)

    Reflects mindset of prescribers and consumerdemand

    Best indicator of marketingor promotional efforteffectiveness

    Data available at nationaland sub-national levels

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    Types of Market Research

    PeriodicSurveys

    PhysicianPanels

    Specialized researchservices to identify patient

    product usage alongspecific variables:

    Diagnosis Patient characteristics Location of visit Drugs used Action desired from

    drugs used

    Tracking of new prescriptions over time andmonitors changes in doctor

    prescribing habits

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    Types of Market Research

    PeriodicSurveys

    Retail PharmacySales

    Historically used for non- prescription pharmaceuticals

    Data typically collected for

    products of interest Collect unit and dollar

    information at the packagesize level

    Main use is to obtain prescription counts by

    product Used for pricing analysis

    and cross-tabulationanalysis using datawarehouses

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    Types of Market Research

    PeriodicSurveys

    PromotionalMedia

    Monitoring of detailingvisits to physicians bysales representatives

    Monitoring of journaladvertising

    Monitoring of direct mail

    advertising Physician sampling

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    Market Research Organizations

    IMS Health Datamonitor Healthcare Consulting Frost.com Reuters Also check out:

    Eyeforpharma.com FDA.gov Journal of the American Hospital Association AMA Drug Evaluations

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    Market Research Industry Associations

    EphMRA European Pharmaceutical ResearchAssociation (www.ephmra.org)

    BHBIA British Healthcare Business IntelligenceAssociation (www.bhbia.org.uk)

    PhRMA Pharmaceutical Research and ManufacturersAssociation (www.phrma.org)

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    SALES

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    Sales Roles Detailing

    Face-to-face visits to physicians or purchasingmanagers (e.g., hospitals, HMOs) to present new

    prescription drugs Influence prescribing habit

    Increase current prescription usage Deliver samples Build relationships with doctors Get drug into a formulary; pull through

    Sample Management Track delivery of prescription drug samples to

    physicians or other purchasers

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    Effective Detailing

    Influences on Physician Prescribing Habits

    Source: IBM Analysis

    Side Effects

    Drug deliverymethod

    Cost of drug

    EfficacyPotential drug-

    druginteractions

    Dosage

    Payorformulary

    status

    Brand

    Personalpreference

    Patient request

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    Detailings Value to the Physician

    I like the good, tangibleinformation about a new drug

    The samples determine what Iprescribe for the long term Samples are extremely valuable I value the relationships with them.

    Overall, I am satisfied with theirservice

    I rely on them to keep me aware of

    whats happening in the drugindustry

    I like their presence to break upmy stressed schedule

    Everybody likes perks

    Comments From PhysicianInterviews

    Learn new drug information

    Get drug samples

    Connect with peers or physicianthought leaders

    Receive the perks

    Establish personal contact withthe drug company

    Provide stress release

    Value of Relationship withPharmaCos to Physicians

    Source: IBM Analysis

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    Detailing - Physician Concerns

    20%Not enough samples

    28%Not enough medical expertise

    40%Take too much time

    44%Too many from the same company

    Inconvenient timing

    Biased information

    What are your top complaints about detailers?

    Source: The Forrester Report: Pharmas Detailing Overhaul, February 2001 (IMS Health, Scott -Levin, Forrester Research, Inc); (Ziment/WebSurveyMD.com); IBM Analysis

    I view them as the liaison but Idont take them at their word allthe time

    I hate negative marketing. Thelack of objectivity is a big turnofffor me

    If they keep coming back with thesame information, its a waste ofboth parties time

    I appreciate the information, butthe reps can be pushy

    The thing I dislike the most iswhen the rep doesnt appreciatethat I am busy and still tries topitch the drug to me

    I dont believe that someone witha bachelors degree knows moreabout how a drug works than I do

    Physician Comments

    78%

    47%

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    Companies Are Experimentingwith e-Detailing

    Source: IMS Health, iPhysicianNet website, Aptilon.com website, IBM Analysis

    There have been promises made about the benefits of e-Detailing

    Benefits to PhysiciansBenefits to PharmaCos

    Cost-effective: an online sales session costsabout $110 on average, compared with about$200 for a field reps office visit

    Cost effective: Increased contact time per visitallows for higher information content

    Better control of detailing content: as a result,e-Detailing can be used as an efficient way totrain less-skilled sales reps

    Capture relevant physician practice data: withthis information, Companies can identifypotential high prescribers that sales reps cantarget later

    Counter detailing and off-the-label discussion:with e- Detailing, the companys medicalexperts can speak with physicians aboutcompeting drugs clinical trial flaws and off -the-label prescription, which is normally notallowed in a sales reps visit

    Increased sales of under-marketed drugs

    Allows physicians to see sales reps,gather information they deem important,and to have the flexibility and control todo it in their own schedule

    Offers physicians a range of convenientinteractive channels

    Provides timely updated druginformation

    Provides simpler sample ordering anddelivery

    Provides quality peer-to-peerdiscussions on a topic that interests aphysician.

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    Sample Management

    The pharmaceutical industry in America distributed$6.7 billion worth of samples to physicians in 1999 *

    During a typical month, the average pharmaceuticalsales representative will visit 150 physicians,distribute thousands of packages of drug samples,obtain FDA required signatures on 150 sampledistribution forms and receive scores of new sample

    cartons to their home-based office, and expend asmuch as 25% of their time tediously managing a paper-based process

    * Source: IMS Health

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    Sample Management andRegulatory Requirements

    PDMA (Prescription Drug Marketing Act) Designed to minimize the threat to the public health

    posed by prescription drug diversion and counterfeiting

    Requires that samples distributed by pharmaceuticalrepresentatives be signed for and tracked to create audittrails

    Helps to ensure that the correct physician receives thecorrect samples. If a pharmaceutical company is found

    to be non-compliant, they could face significant penalties, fines, and possibly even prison terms

    Source: FDA

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    OTH ER M ARKETI NG& SAL ES TECH NI QUES

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    Key Opinion Leader Management

    Expert physicians -- often called "opinion leaders" or "thought leaders"-- play critical roles in driving pharmaceutical sales Participate in ongoing R&D Have privileged access to R&D information Company-sponsored featured speaking engagements at prestigious

    conferences

    Exchange ideas with other physicians regarding new products orindications or adverse events

    Helps convince other doctors to prescribe new products and can makethe difference between a successful product launch and a majordisappointment

    Program is actively integrated with marketing program: Physician recruitment (specialty, name recognition, etc.) Matching to appropriate R&D efforts Matching to appropriate marketing programs

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    Medical Science Liaisons (MSLs)

    Scientific professionals Pharmaceutical PhDs Pharmacists Physicians Nurses

    Generally have more scientific knowledge than sales representatives Roles:

    Support and expand sales representatives marketing of a product Be able to speak to the purchaser on a more scientific (peer) level; not on a

    marketing level Will focus on clinical information

    Focus on key opinion leaders Typically will only see more knowledgeable sales reps Organize symposia, conferences, focus groups, etc. Training and continuing education programs

    May be involved in setting up Phase IV trials (post launch)