male genitaltract 3

Male Genital Tract Pathology-3

Dr.CSBR.Prasad, M.D.

Epididymitis

CSBRP-July-2012

Granulomatous epididymitis

Penis

CSBRP-July-2012

Congenital anomalies

• Hypospadias

• Epispadias

• Phimosis

• Paraphymosis

CSBRP-July-2012

Hypospadias

Epispadias • Malformations of urethral groove and urethral canal

may create an abnormal opening.

--ventral surface (hypospadias)

--dorsal surface (epispadias)

It may be associated with abnormalities in

--descent of testes

--malformation of urinary tract

Complications: infections of urinary tract

infertility

CSBRP-July-2012

The catheter seen here is in a groove on the undersurface below the tip of the penis and

enters the urethra. This abnormal opening is known as a hypospadias. Such an anomaly

is not common but can lead to problems with urination and ejaculation. CSBRP-July-2012

The groove on the dorsal aspect of the penis extending from the urethral meatus is an abnormality

termed epispadias. This is an uncommon anomaly of varying degrees of severity. When severe, it

can lead to problems with urination and ejaculation.

CSBRP-July-2012

Infalmmations

Balanoposthitis

Specific infections: syphilis, gonorrhea, chancroid,

Granuloma inguinale, Herpes.

Non-specific infections: Candida albicnas, Gardnerella,

pyogenic bacteria

CSBRP-July-2012

The glans penis surrounding the penile urethral meatus demonstrates erythema and

exudate, typical for a balanitis. The retracted foreskin is also acutely inflamed, a

condition called posthitis. Together, this inflammatory condition is known as

balanoposthitis. CSBRP-July-2012

Syphilitic chancre occurring on the glans penis CSBRP-July-2012

Condyloma accuminatum

•HPV 6 & 11

•Sexually transmitted

•Most lesions occur in the coronal sulcus

•Single / multiple sessile or pedunculated red papillary

excrescences

•Histologically acanthosis, hyperkeratosis, koilocytosis

•They tend to recurr

•No malignant potential

•Giant condylomas are known as Buschke-Lowenstein

tumor CSBRP-July-2012

CSBRP-July-2012

Large confluent 1 cm to 8 cm hyperpigmented warty nodules.

CSBRP-July-2012

Large confluent 1 cm to 8 cm hyperpigmented warty nodules

CSBRP-July-2012

CSBRP-July-2012

Bowen’s disease •>35yrs

•Shaft of the penis and scrotum

•Solitary, thickened, gray white, opaque plaque with shallow

ulceration and crusting

•On the glans it produces velvety lesion

•Histologically: acanthosis, mitoses, dysplasia and other nuclear

features of malignancy

•Dermo-epidermal margin is well demarcated.

•Develops in to carcinoma

•Bowenoid papulosis: younger age, HPV-16, resembles condyloma,

No malignant potential CSBRP-July-2012

Bowenoid papulosis - Scrotum

CSBRP-July-2012

Squamous cell carcinoma – Penis

•Correlation exists between circumcision and occurance of

Ca

•HPV 16 & 18

•Bowen’s disease

•Others: smoking

•Age: 40-70yrs

•Morphology: glans and inner surface of prepuce near

coronal sulcus, Papillary / flat

•Verrucous carcinoma: WD scc, low malignant potential,

locally invasive, rarely metastsizing

CSBRP-July-2012

Here is a squamous cell carcinoma of the head of an uncircumcised

penis. The neoplasm is reddish-tan with an ulcerated surface

This is a squamous cell carcinoma of the penis (penectomy specimen)

that is a larger, reddish brown fungating mass

Papillomatous growth

pattern

CSBRP-July-2012

Penile squamous cell carcinoma involving the glans in a vegetant fashion

CSBRP-July-2012

Verrucous carcinoma

Bulbous expansions of verrucous carcinoma CSBRP-July-2012

Why these people are more prone

for carcinoma of penis ?

CSBRP-July-2012

E N D

CSBRP-July-2012

Contact:

Dr.CSBR.Prasad, M.D.,

Associate Professor of Pathology,

Sri Devaraj Urs Medical College,

Kolar-563101,

Karnataka,

INDIA.

[email protected]

male genitaltract 3

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