makers of the world’s most advanced medical acrylics.€¦ · · 2018-01-31sterrad...
TRANSCRIPT
Makers of the world’s most advanced medical acrylics.
Where do the most brilliant ideas come from? Some are born
within. Some are born from prior innovation. For decades,
CYRO’s acrylic-based compounds have been bringing brilliant
ideas into the realm of possibility for medical designers and
medical manufacturers everywhere.
CYRO’s line of medical polymers offers a superior balance of
properties and can be utilized in a variety of medical-oriented
applications. These include Medical Devices, Medical Packaging
and Medical Diagnostics. These compounds can be injection
molded, extruded and thermoformed. And, regardless of the
specific application, they consistently exhibit an unsurpassed
level of performance in processing, bondability, toughness,
chemical resistance, sterilization and optics.
Table of Contents
Medical Devices Pages 3-5
Medical Packaging Pages 6-8
Physiochemical and Drug Compatibility Properties for Pharmaceutical Contact Applications Page 9
STERRAD Sterilization Page 10
Medical Diagnostics Page 11
Environmental Page 11
Regulatory Page 11
You’ll find that some of the most brilliant ideas come
from CYRO’s acrylic-based multipolymer compounds.
2
CYRO offers the most advanced acrylic solutions for the
medical device industry. Products such as CYROLITE®
acrylic-based multipolymer compounds and CYREX®
acrylic-polycarbonate alloys are the true embodiment
of innovation. Both of these superior compounds exhibit
excellent characteristics for the most demanding and
diverse medical device applications.
Performance.This word, without a doubt, best describes
CYROLITE compounds.That’s because CYROLITE
compounds offer the very best balance of properties for
medical device applications. All grades of CYROLITE
compounds are engineered for applications where gamma
or e-beam sterilization is required, as they invariably
demonstrate no loss in properties. CYROLITE compounds
are easy to process and can be used for very intricate to
very large medical device parts. Every grade offers unique
characteristics and a variety of benefits. However, they are
all tough, transparent, bondable, gamma, e-beam and EtO
sterilizable, and chemically resistant. In other words, they
are just what you need.
Elongation retention after exposure to stress in presence of a chemical has been found to be a good measure of chemical resistance.
Initial Elongation @ break, %
Lipid ResistantPolycarbonate
140.0
CYROLITE Med 2Compound
14.8
IPA Exposure@ 2.0% Strain/5 hrs @ 23°CElongation @ break
% Retention of Elongation @ break
6.04.0
22.8154.0
Lipid Solution Exposure @ 2.0% Strain/24 hrs @ 23°CElongation @ break
% Retention of Elongation @ break
4.0
3.0
17.7
106.0
Chemical Resistance to Lipids and IPA
Chemical Resistance as a Function of StrainCYROLITE Med 2 Compound vs Lipid Resistant Polycarbonate
Elo
ngat
ion
Ret
enti
on,
%
0
50
100
150
200
CYROLITE Med 2 Lipid resistant PC
ISOPROPANOL (IPA) RESISTANCE @ 2.0% Strain/5 hrs @ 23°C
LIPID RESISTANCE @ 2.0% Strain/24 hrs @ 23°C
CYROLITE Med 2
Elo
ngat
ion
Ret
enti
on,
%
Lipid resistant PC
0
20
40
60
80
100
120
“ ”“CYROLITE Med 2 provided excellent processing and
consistent results in G Force expansion. Because the tube'sshape is so critical to process, the tube must consistentlyretain the exact mold shape without deviation. We foundthe CYROLITE compound easy to work with, and it consistently held the mold design without tapering.”
– Joel Higgins, Director of Resorbables Engineering, Biomet
“ ”“We chose CYROLITE CG-97 compound for the housing
because its chemical-resistant properties improve thedurability and functionality of the Medipure IV Filter.”
– John Leahey, Senior Program Manager, Filtertek
Breakthrough Chemical Resistance to Lipids and IPA Subjecting parts made with CYROLITE Med 2 compound to stress tests in the presence of lipid and alcohol solutionsdemonstrates unprecedented retention of performanceproperties by an acrylic-based material.
3
When it comes to Medical Device applications, CYREX
200-8005 acrylic-polycarbonate alloy will exceed all your
expectations — and then some.This advanced alloy is
formulated specifically for the medical industry and offers
a unique combination of properties that will enhance the
performance of medical devices that are particularly
opaque. CYREX 200-8005 alloy exhibits exceptional
toughness characteristics and is chemically resistant to
both alcohol and lipids. In addition, it is EtO, e-beam and
gamma sterilizable, and easy to process. In fact, it can
be processed at lower temperatures than straight polycar-
bonate, which will decrease the cooling time and in turn
decrease the cycle time of an injection molding process.
Vu-Stat™ static dissipative acrylic multipolymer compounds
are transparent, electro-static dissipative compounds
that have outstanding ESD properties and an excellent
balance of mechanical, thermal and flow properties.
Vu-Stat compounds provide permanent ESD protection
for parts that are sensitive to static discharge.
CYRO Industries offers two grades of Vu-Stat compounds
for medical device applications requiring a transparent,
tough, anti-static compound. Applications would include
those involving inhalation drug delivery where a static-free
mouthpiece and spacer mean more of the drug is delivered
to the patient. In bracheotherapy applications, a static-free
needle hub environment makes delivery of radioactive
materials to the patient much easier.Vu-Stat compounds are
inherently anti-static and do not depend on relative humidity
to deliver static-free results.The material retains permanent
static dissipative properties even after many washings.
The CYRO AdvantageBondability: CYRO’s medical polymers offer excellent and
consistent bonding to PVC tubing and other mating plastics
and are superior to ABS types of plastic. Parts can be
solvent or thermal-bonded and ultrasonic or spin-welded.
Typical bonding solvents are: cyclohexanone (excellent
for bonding vinyl), tetrahydrofuran, methyl methacrylate
monomer, methyl ethyl ketone and toluene. Cyanoacrylate
and UV curable adhesives are also recommended. It is
important to remember that all solvents should be evaluated
for suitability and applicability and should be handled only
by qualified persons familiar with their potential hazards.
Welding: CYRO’s medical polymers can be readily welded
using radio frequency, ultrasonic, vibration, spin or hot plate
welding. Radio frequency welding is the process of fusing
materials together by applying radio frequency energy.
Ultrasonic, vibration and spin welding methods utilize
friction to melt the materials at the weld interface.
Hot plate welding uses heating elements to transfer energy
that softens or diffuses the surfaces prior to pressing them
together. Ultrasonic welding is probably the most popular
method for welding thermoplastic materials.
Sterilization: CYRO’s medical polymers can be sterilized
by either ethylene oxide gas or radiation techniques.
CYROLITE GS-90 and CYROLITE CG-97 acrylic-
based multipolymer compounds make a permanent,
slight color change to a pleasing blue-green tint after
being radiated, which allows medical parts to be sent
to market immediately after irradiation.
CYROLITE G-20, CYROLITE G-20 HIFLO®, and
CYROLITE Med 2 acrylic-based multipolymer
compounds have an initial color change that returns
to near normal appearance after four to five weeks.
CYREX 200-8005 acrylic-polycarbonate alloy is a
medical grade white product that exhibits very little
change after gamma exposure.
Vu-Stat compounds experience an initial color change
after gamma or e-beam exposure.The change in color
returns to near normal appearance after four weeks.
EtO has little or no affect on the appearance.
All CYROLITE and XT compounds can be sterilized
using the STERRAD® Sterilization System. See page 10.
4
Processability: CYRO’s medical polymers are easy to
injection mold and are readily adaptable to tooling designed
for styrene, vinyl, ABS and polycarbonate.The cycle time in
injection molding is excellent, and the regrind can be readily
used. All grades offer exceptional ease of processing.
However, CYROLITE G-20 HIFLO and CYROLITE GS-90
compounds are the most superior in this category. In addition,
CYROLITE Med 2 compound has excellent processability
at low temperatures, and its high flowability as measured by
spiral flow is perfect for extremely thin-walled applications
and complex multicavity molds.
Optics: Transparent CYRO medical polymers offer high
light transmission with little haze.They can be easily
pigmented or dyed to a wide variety of transparent and
opaque colors.
Chemical Resistance: All CYRO medical polymers offer
resistance to body fluids and many chemicals, especially
plasticizers. However, for superior chemical resistance,
including resistance to alcohol and lipids, CYROLITE
CG-97 and CYROLITE Med 2 compounds are in a class
of their own.
Toughness and Impact Resistance: CYRO’s medical
polymers offer a variety of products and grades that can
meet any number of toughness and impact resistance
needs. CYREX 200-8005 alloy offers the maximum
impact resistance, boasting a notched Izod impact of 15.7.
Typical medical device applications include:• Lures
• Spikes
• Fittings
• Nozzles
• Protection caps and covers
• Blood plasma separators
• Collection and specimen vessels
• Needle and tube collars or adapters
• Catheter accessories
• Chest drainage units
• Valve assemblies
• Meter housings
• Flow controls
• Filter housings
• Drip chambers
• IV adapters
• Yankauers
• Rigid tubes
• Bracheotherapy needle hubs
• Inhalation mouthpieces and spacers
At-A-Glance — Medical Devices
GRADE FLOW COMMENT
CYROLITE G-20 Intermediate More chemically resistant than CYROLITE G-20 HIFLO
CYROLITE G-20 HIFLO High Highest melt flow
CYROLITE GS-90 High Best appearance after gamma sterilization
CYROLITE CG-97 Intermediate Superior lipid resistance and very good alcohol resistance; highest impact
CYROLITE Med 2 Intermediate Superior alcohol and lipid resistance; best ductility
Vu-Stat High Inherently anti-static; excellent balance of mechanical, thermal and flow properties
CYREX 200-8005 Medium Maximum toughness and chemical resistance; opaque5
15
17
19
21
23
25
27
29
31
33
35
PCTG TABS Lipid ResistPC at 625°F
HIGHFLOW PCat 575°F
CYROLITEG-20
CYROLITECG-97
CYROLITEMed 2
CYROLITEG-20
HIFLO
VU-STAT CYROLITEGS-90
Inch
es
Spiral Flow (In) 0.125" Depth, Melt at 450ºF, Mold at 105ºF
XT® polymer acrylic-based multipolymer compounds are
transparent, impact modified acrylic-based multipolymer
compounds that offer exceptional chemical resistance,
including resistance to plasticizers found in PVC and other
flexible plastics. XT polymer compounds offer good heat
distortion temperature, outstanding impact strength and
are all suitable for ethylene oxide sterilization. Moreover,
XT polymer compounds are resistant to body fluids and
have a high light transmission.
XT polymer compounds are designed to withstand the
toughest conditions in medical packaging. Best of all, they
consistently outperform PETG in both notched Izod impact
strength and tensile elongation testing after EtO sterilization.
XT polymer compounds consist of four different grades
varying in molecular weight and rubber loading.
Xtreme Performance• Superior EtO resistance over PETG
• Resistant to PVC plasticizers
• Resistant to gamma and e-beam sterilization
• Superior heat distortion temperatures
• Outstanding thermoformability
• Excellent rigidity
• Tamper-evident that will stress-whiten if punctured
• Can be down-gauged, resulting in improved cost
and source reduction
• Can be used with most lidding stock
and bonding techniques
• Outstanding transparency for easy inspection
• Easily stackable, eliminating silicone
migration concerns
• Reuse of regrind offers economic
and environmental benefits
• Incineration: No generation of supertoxins
makes for easy incinerationAt-A-Glance — Medical Packaging
GRADE FLOW COMMENT
XT polymer 250 Medium Desirable balance between processability and chemical resistance
XT polymer 375 Stiff Best chemical resistance of XT polymer compound grades
XT polymer 375TE Stiff Allows for easy seal inspection
XT polymer X800RG High Easiest to process; most clarity in thin gauge packaging
XT polymer compounds toughness characteristics are evident in its combination of Izod impact and elongation at break characteristics. Both these properties remain stableafter EtO exposure and over time as demonstrated in thetables and graphs on page 7. PETG's toughness characteristicsare related to its elongation at break property. After EtO sterilization, the elongation property of PETG is immediatelyreduced by half after which it continues to deteriorate as itages until it becomes fairly brittle.
6
Heat Aging of XT Polymer Compounds for Medical PackagingStandard: ASTM D 3045 "Standard Practice for Heat Aging of Plastics Without Load" Conditions: Temperature = 50ºC EtO Sterilization: Standard Hospital Cycle
Tensile Elongation Tensile Flexural Flexural Izod Impact Deflection Strength1 @ break1 Modulus1 Strength2 Modulus2 Resistance3 Temperature4
psi % kpsi psi kpsi fppi @ 23ºC ºC
XT 375TEUnsterilized 8220 11 399 12700 370 2.05 78EtO Sterilized 8270 7 400 12800 365 2.07 80Accelerated Aging 3 weeks 8300 11 416 13250 358 2.03 856 weeks 8100 12 416 13050 378 2.08 8512 weeks 7970 10 390 12500 352 2.13 83
XT 375Unsterilized 8310 11 393 12740 357 2.03 80EtO Sterilized 8200 9 387 13300 401 2.03 80Accelerated Aging 3 weeks 8330 7 410 13400 388 2.00 846 weeks 7940 8 409 13380 374 2.04 8612 weeks 8100 11 388 12720 369 2.05 84
XT X800RG Unsterilized 7213 6 335 9300 353 2.21 80EtO Sterilized 7340 7 353 9600 307 2.25 81Accelerated Aging 3 weeks 7250 7 368 11220 330 2.20 866 weeks 7110 9 346 11500 318 2.29 8612 weeks 7140 8 343 11100 344 2.35 85
PETG 6763Unsterilized 7600 104 299 11200 272 0.55 70EtO Sterilized 8000 50 314 12100 268 0.54 73Accelerated Aging 3 weeks 8900 33 310 13050 280 0.51 796 weeks 9240 21 303 13350 290 0.55 8012 weeks 9700 5 328 13210 288 0.54 79
1ASTM D 638 Heat Aging correlation* to real-time (storage @ 22ºC): * Aging Rate = Q10 2ASTM D 790 3 weeks = 145 days Q10 = 2.0 Aging Rate = 6.96 3ASTM D 256; 1/4" [6.35 mm] bar 6 weeks = 290 days Heat Aging = Real Time Aging/Aging Rate 4ASTM D 648; @ 264 psi, annealed 12 weeks = 580 days Heat Aging = Real Time Aging/6.96
Heat Aging – Notched IzodASTM D 3045 "Standard Practice for Heat Aging of Plastics Without Load"
Exposure Conditions: 50ºCEthylene Oxide Sterilization: Standard Hospital Cycle
ASTM D 256; Noched Izod @ 23ºC
0
1
2
3
4
5
Initial EtO Sterilized 3 weeks 6 weeks 12 weeks
Heat Aging Exposure Time
No
tche
d Iz
od
, fp
pi
XT 375TE XT 375 XT X800RG PETG 6763
Unsterilized
Heat Aging – Tensile ElongationASTM D 3045 "Standard Practice for Heat Aging of Plastics Without Load"
Exposure Conditions: 50ºCEthylene Oxide Sterilization: Standard Hospital Cycle
ASTM D 638; Elongation @ Break
0
10
20
30
40
50
60
70
80
90
100
110
120
Initial EtO Sterilized 3 weeks 6 weeks 12 weeks
Heat Aging Exposure Time
Tens
ile E
long
atio
n @
Bre
ak, %
XT 375TE XT 375 XT X800RG PETG 6763
Unsterilized
((Elevated temp. - Ambient)/10)
7
All grades of XT polymer compoundsexcel in the medical packaging industry.
PETG 6763
XT polymer 375TE
F = FlangeW = Side wallC = CornerBC = Bottom next to cornerB = Mid bottom
Wall Thickness Distribution Typical vacuum forming conditions XT polymer vs PETG 6763
Areal Draw Ratio: 1.8:1Sheet Thickness ~ 25 mils
110
100
90
80
70
60
50F W C BC B
Measurement Location
Thermoforming Characterization
B BC C W F
Wal
l Thi
ckne
ss, %
100100
78
67
81
99
70
63
71
92
-5
-2.5
0
2.5
5
Initial Day5
Day7
Day9
Day12
Day15
Day20
Day25
Day30
17 mils
Yel
low
nes
s In
dex
25 mils 40 mils
on Yellowness Index with Respect to Film Thickness
XT Polymer 375TE — Effect of Gamma Irradiation (25 kGys)
-5
-2.5
0
2.5
5
Initial Day5
Day7
Day10
Day14
Day20
Day25
Day30
17 mils
Yel
low
nes
s In
dex
25 mils 40 mils
on Yellowness Index with Respect to Film Thickness
XT Polymer 375TE — Effect of EtO Sterilization
XT polymer compounds made into thin gauge sheet for medical packaging trays canbe sterilized either by gamma or EtO with little loss of properties or appearance.
8
XT polymer compounds excel in thermo-forming because they resist shear thinning more than many other thermo-plastic materials such as PETG. Shear thinning resistance allows thermoformedparts to have better wall thickness distribution as well as stronger walls and corners.
The graph provides an overview of the material distribution of both XT polymer 375TE compound and PETG in a thermoformed part. The original sheetthickness of both materials starts at 25mils. Both sheets are thermoformed in the same tool with an areal draw ratio of1.8:1. At point W (wall), XT polymer 375TEcompound retains 78% of its originalthickness and PETG 70%. At point C
(corner), XT polymer 375TE compoundretains 67% of its original thickness and PETG 63%. At point B (bottom), XTpolymer 375TE compound retains 99%and PETG only 92%.
Astute Packaging Engineers will recognizesignificant cost savings by choosing packaging trays made from XT polymercompounds — even if sheet made fromXT polymer compounds cost more on aper pound basis than PETG. XT polymer compounds offer a 13% specific gravitysavings over PETG and, because they are significantly more rigid, they offer valuabledown-gauging possibilities. (The betterdistribution of material during thermo-forming also allows for further down-gauging potential).
Physiochemical and Drug CompatibilityProperties for Pharmaceutical ContactApplications – CYROLITE, XT polymer and CYREX You’ll be happy to know that CYROLITE and
XT polymer compounds and CYREX alloys are
contact compatible with a variety of pharmaceutical
treatment drugs and carriers. Moreover, these
compounds also pass requirements for United
States Pharmacopoeia 26, National Formulary
21, 2003 <661> “Physiochemical Tests –
Plastics” – Containers, for containers intended
for pharmaceutical treatment drugs and solutions.
For further information on these test results, you
can contact your CYRO Representative.
CYROLITE and XT polymer compounds and
CYREX alloys have been tested for compatibility
with human insulin solution,Taxol®*, Heparin,
protein solution and common drug treatment
carrier solutions.
LIPID RESISTANCEAt 1.2% Strain/24 hrs @ 30°C At 0.9% Strain/3 hrs @ 20°C At 0.9% Strain/5 hrs @ 20°C
TENSILE STRENGTH ELONGATION AT BREAK TENSILE STRENGTH ELONGATION AT BREAK
60
80
100
120
20
0
40
ISOPROPANOL ALCOHOL RESISTANCE ISOPROPANOL ALCOHOL RESISTANCE
Pro
pe
rty
Re
ten
tio
n,
%
TENSILE STRENGTH ELONGATION AT BREAK
XT polymer 375 XT polymer 250 CYROLITE G-20 CYROLITE GS-90 CYROLITE CG-97 CYROLITE Med 2
CYRO ACRYLIC POLYMERS PRODUCT KEY
Chemical Resistance At-A-Glance
9
It’s important to note that a CYRO product’s applicability in a given end-use environmentis dependent on a number of conditions including, without limitation, chemical compatibility,temperature, part design, sterilization method, residual stresses and external loads. It is the responsibility of the manufacturer to evaluate its final product under actual end-userequirements and to adequately advise and warn purchasers and users thereof.
*Taxol® is a registered trademark of Bristol-Myers Squibb Company.
STERRAD Sterilization – CYROLITE and XT polymerCYROLITE and XT polymer compounds can be
sterilized using the STERRAD®* Sterilization System.
The Johnson & Johnson STERRAD System utilizes
a combination of hydrogen peroxide vapor and
low-temperature gas plasma to rapidly sterilize most
medical instruments and materials without leaving
any toxic residues.Tests show that CYROLITE and
XT polymer compounds tensile strength and elongation
properties are not adversely affected by STERRAD
sterilization.This sterilization process does affect the
haze of XT polymer and CYROLITE compound products.
XT 250 XT 375 G-20 HIFLO GS-90 CG-97
0
5
10
15
20
Tens
ile E
long
atio
n at
Bre
ak, %
STERRAD Sterilization Effectson XT Polymer and CYROLITE Compounds
Elongation at break, % Elongation at break, % – Sterilized
XT 250 XT 375 G-20 HIFLO GS-90 CG-97
2,000
0
4,000
6,000
8,000
10,000
STERRAD Effects on Tensile Strengthof XT Polymer and CYROLITE Compounds
Tensile Strength, psi Tensile Strength – Sterilized, psi
Tens
ile S
tren
gth
, psi
XT 250 XT 375 G-20 HIFLO GS-90 CG-97
0
5
10
15
20
25
Haz
e, %
STERRAD Sterilization Effects on Hazeof XT Polymer and CYROLITE Compounds
Haze, % Haze, % – Sterilized
10
*STERRAD® is a registered trademark of Johnson & Johnson.
ACRYLITE acrylic polymers are ideal for medical
diagnostic applications because they offer optical clarity
or maximum visible and ultraviolet light transmitting
characteristics.They are also easy to process and exhibit
good dimensional stability.
ACRYLITE polymers are available in a number of grades
and have excellent optical properties, which make them
ideal for many uses.They are completely transparent and
are essentially colorless.
In making optical diagnostic components, the purity of the
polymers is paramount.When manufacturing ACRYLITE
polymers, a great deal of attention is given to ultraviolet
visible light transparency and cleanliness. In fact,
ACRYLITE polymers are subject to the strictest standards
in production quality control.
ACRYLITE polymers are used extensively in medical
diagnostic applications:
• Diagnostic cuvettes
• Diagnostic test packs
• Diagnostic rotors
CYRO’s products comply with the following Tripartite, ISO 10993-1, USP and FDA regulations.
Regulatory RequirementsGrade Food Contact*1 USP Class VI*2 Tripartite*3
XT polymer 250 compound Yes Yes*4 Yes*6
XT polymer 375 compound Yes Yes*4 Yes*6
XT polymer 375TE compound Yes Pending Not Tested
XT polymer X800RG compound Yes Yes Not Tested
CYROLITE G-20 compound Yes Yes*5 Yes*5
CYROLITE G-20 HIFLO compound Yes Yes*5 Yes*5
CYROLITE CG-97 compound Yes Yes*5 Yes*5
CYROLITE GS-90 compound Yes Yes*5 Yes*5
CYROLITE Med 2 compound Not Tested Yes*5 Yes*5
CYREX 200-8005 alloy Yes Yes*7 Yes*7
Vu-Stat C-37 compound Not Tested Not Tested Not Tested
Vu-Stat Y-20 compound Not Tested Yes*5 Yes*5
ACRYLITE polymers Yes Yes*8 Yes*8
*1 Products meet the requirements in
21CFR177.1010, 21CFR180.22, and
21CFR177.1580 as appropriate to the
specific product.
*2 Class VI United States Pharmacopoeia tests for
determining the suitability of a plastic material
intended for use in fabricating containers or
accessories thereto, for parenteral preparations.
*3 Indicated products have been found to be
non-hemolytic, non-cytotoxic, non-pyrogenic,
non-sensitizing and non-mutagenic when
tested following the Tripartite and
ISO 10993-1 Protocols.
*4 In natural and 301 tints only;
not tested in other colors.
*5 In 001 tint only; not tested in other colors.
*6 In 301 tint only; not tested in other colors.
*7 In 8005 color only.
*8 ACRYLITE H-10 polymers not tested.
Source Reduction and Incineration: XT polymer and
CYROLITE compounds can be recycled, reprocessed and are
compatible with many other polymers such as polystyrene.
XT polymer and CYROLITE compounds, as well as
ACRYLITE polymers, can be safely incinerated and
are safe to landfill. Reducing the amount of material that
enters the waste system is the preferred method of making
waste more manageable. Some source reduction techniques
include: elimination of parts/packing; thin walling/material
efficiency; use of concentrates; refills; reduction in toxicity;
increase in life expectancy and elimination of planned
obsolescence. CYRO molding compounds lend themselves
to many of these techniques.
11
All CYRO manufacturing facilities are ISO 9001:2000 Certified.CYRO plants are located in Wallingford, CT; Westwego, LA;Sanford, ME and Osceola, AR. Attaining ISO registration at allfour CYRO facilities insures CYRO will continue to improve itsprocess, products and service performance.
HEADQUARTERS:CYRO Industries100 Enterprise DriveRockaway, NJ 07866973-442-6000800-631-5384
SALES OFFICES:US & CanadaXT polymers & CYROLITE compounds100 Enterprise DriveRockaway, NJ 07866973-442-6000
ACRYLITE polymers25055 West Valley ParkwaySuite 129Olathe, KS 66061913-254-9404
South/Latin America100 Enterprise DriveRockaway, NJ 07866973-442-6086
Europe, Africa & The Asia Pacific RegionDegussa AGKirschenallee64293 DarmstadtGermany49-6151-184334
CUSTOMER SERVICE:United States & Canada800-225-0172
South/Latin America973-442-6086
Europe, Africa & The Asia Pacific Region49-6151-184775
TECHNICAL SUPPORT:Visit the TechKnowlogy Center at www.cyro.comwhere visitors have immediate access to FAQ,technical information, tips, and hundreds of otherfacts about acrylic-based polymers.
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