maintenance of therapeutic hypothermia during critical...

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To determine if the EXCEL ® Cooling Collar can be used to prevent core body temperature rise during critical care interfacility transport of TH ROSC patients Objective The EXCEL ® Cooling Collar appears to prevent statistically or clinically significant core body temperature rise in patients for whom TH was initiated. All patients remained within the target temperature range. Limitations of this study include the lack of a control group. Additionally, patient outcomes and initial rhythms were not monitored as a part of this trial. Finally, this initial abstract has a small n and further research is being completed with a targeted goal of 30 patients. Conclusions 1. Da Silva, Ferreira and JA Frontera, Targeted temperature management in survivors of cardiac arrest, Journal of Clinical Cardiology, 2013 Nov;31(4)637-55 2. Azmoon, S et al, Neurologic and cardiac benefits of therapeutic hypothermia, Cardiol Rev, 2011 May-June; 19(3): 108-14 3. Peberdy, Mary Ann, et al, Post Cardiac Arrest Care: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care, Circulation 2010; 122:S768-s78 References Maintenance of Therapeutic Hypothermia During Critical Care Interfacilty Transport Kevin Collopy BA, FP-C, CCEMT-P, NR-P; Timothy Oster, MD; Kevin Hodge, RN CFRN; Claire Corbett, MMS NR-P; Abby Roetger, MS NHRMC AirLink/VitaLink Critical Care Transport Introduction Early initiation of mild therapeutic hypothermia (TH) is currently a standard of care following cardiac arrest (CA) and hasbeen demonstrated to decrease morbidity and mortality. Current guidelines recommend patients reach target temperature (32-34 o C) within 6 hours of return of spontaneous circulation (ROSC). Earlier cooling has been shown to improve outcomes compared to instances where cooling is delayed. When ROSC patients require transfer from a referral emergency department to tertiary care, the initiation of TH is often delayed until transport teams arrive because there are no proven strategies to maintain TH during transfer. To date, no trials have evaluated the effectiveness of any interfacility transport TH maintenance strategies. This study aims to determine if the EXCEL ® Cooling Collar can prevent core body temperature rise during transport of TH patients. 87.00 88.00 89.00 90.00 91.00 92.00 93.00 94.00 95.00 96.00 Baseline (time 0) 15 30 45 60 75 90 Esophageal Temp (°F) Figure 1: Esophageal Temperature With Excell ® Cooling Collar Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Patient 6 Methods This is an IRB approved prospective case series of all patients for whom TH was initiated at a referral ED and accepted for admission at NHRMC between 1 March 2013 & 1 April 2014. All patients received a 2000mL iced (4 o C) Normal Saline (NS) infusion to standardize initial cooling. Following the NS bolus, the transport team obtained a baseline esophageal temperature and applied the EXCEL ® Cooling Collar; all other cooling strategies were discontinued. Shivering was managed following existing protocols. Esophageal temperatures were recorded every 15 minutes, and the cooling element exchanged every 20 minutes per manufacturer recommendations. Final temperatures were documented upon arrival at the intensive care unit. A paired t test was performed to determine if significant temperature change occurred. Of the 18 patients transferred for post arrest TH, 6 had their NS bolus completed, had the EXCEL ® Cooling Collar deployed and were included in the study. Patients experienced a mean temperature decrease of 1.28 o F (Figure 1), which was found to be statistically insignificant (p=0.0537). No complications including re-arrest, new hypotension, or death occurred while the study device was in use. Results

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Page 1: Maintenance of Therapeutic Hypothermia During Critical ...cryothermicsystems.com/wp-content/uploads/2016/09/... · •Early initiation of mild therapeutic hypothermia (TH) is currently

To determine if the EXCEL® Cooling Collar can be used to prevent core body

temperature rise during critical care interfacility transport of TH ROSC patients

Objective

• The EXCEL® Cooling Collar appears to prevent

statistically or clinically significant core body

temperature rise in patients for whom TH was initiated.

• All patients remained within the target temperature range.

• Limitations of this study include the lack of a control group. Additionally, patient outcomes and initial rhythms were not monitored as a part of this trial.

• Finally, this initial abstract has a small n and

further research is being completed with a targeted goal of 30 patients.

Conclusions

1. Da Silva, Ferreira and JA Frontera, Targeted temperature management in survivors of

cardiac arrest, Journal of Clinical Cardiology, 2013 Nov;31(4)637-55

2. Azmoon, S et al, Neurologic and cardiac

benefits of therapeutic hypothermia, Cardiol Rev, 2011 May-June; 19(3): 108-14

3. Peberdy, Mary Ann, et al, Post Cardiac Arrest Care: 2010 American Heart Association

Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care, Circulation

2010; 122:S768-s78

References

Maintenance of Therapeutic Hypothermia During Critical Care Interfacilty Transport Kevin Collopy BA, FP-C, CCEMT-P, NR-P; Timothy Oster, MD;

Kevin Hodge, RN CFRN; Claire Corbett, MMS NR-P; Abby Roetger, MS NHRMC AirLink/VitaLink Critical Care Transport

Introduction

• Early initiation of mild therapeutic hypothermia (TH) is currently a standard of care following cardiac arrest (CA) and hasbeen demonstrated to decrease morbidity and mortality.

• Current guidelines recommend patients reach target temperature (32-34oC) within 6 hours of return of spontaneous circulation (ROSC).

• Earlier cooling has been shown to improve outcomes compared to instances where cooling

is delayed.

• When ROSC patients require transfer from a referral emergency department to tertiary care, the initiation of TH is often delayed until transport teams arrive because there are no proven strategies to maintain TH during

transfer.

• To date, no trials have evaluated the

effectiveness of any interfacility transport TH maintenance strategies.

• This study aims to determine if the EXCEL®

Cooling Collar can prevent core body

temperature rise during transport of TH patients.

87.00

88.00

89.00

90.00

91.00

92.00

93.00

94.00

95.00

96.00

Baseline

(time 0)

15 30 45 60 75 90

Eso

ph

ag

ea

l T

emp

(°F

)

Figure 1: Esophageal Temperature With Excell® Cooling Collar

Patient 1

Patient 2

Patient 3

Patient 4

Patient 5

Patient 6

Methods

• This is an IRB approved prospective case series of

all patients for whom TH was initiated at a referral ED and accepted for admission at NHRMC between 1 March 2013 & 1 April 2014.

• All patients received a 2000mL iced (4oC) Normal Saline (NS) infusion to standardize initial cooling.

• Following the NS bolus, the transport team obtained a baseline esophageal temperature and applied the EXCEL® Cooling Collar; all other cooling strategies were discontinued.

• Shivering was managed following existing protocols.

• Esophageal temperatures were recorded every

15 minutes, and the cooling element exchanged

every 20 minutes per manufacturer recommendations.

• Final temperatures were documented upon arrival at the intensive care unit. A paired t test

was performed to determine if significant temperature change occurred.

• Of the 18 patients transferred for post arrest

TH, 6 had their NS bolus completed, had the EXCEL® Cooling Collar deployed and were included in the study.

• Patients experienced a mean temperature decrease of 1.28oF (Figure 1), which was found

to be statistically insignificant (p=0.0537).

• No complications including re-arrest, new hypotension, or death occurred while the study

device was in use.

Results