Ludwig Merzbacher

Ludwig Merzbacher (ca. 1925)

Ludwig Merzbacher (February 9, 1875 – 1942) wasa German-Argentine neuropathologist and psychiatristborn in Florence, Italy.In 1900 he received his medical doctorate fromthe University of Strassburg, afterwards remaining inStrassburg as an assistant at the physiological institute.Later he worked at psychiatric clinics in Freiburg (1902–04) and Heidelberg (1904–06), obtaining his habilitationfor psychiatry in 1906 at the University of Tübingen.From 1906 until 1910 he worked at the psychiatric clinicin Tübingen, where he was an assistant to Robert Gaupp(1870–1953). During this time period, he also spent sev-eral months in Munich, conducting research in the lab-oratory of Alois Alzheimer (1864-1915). Here he per-formed in-depth analysis on the reaction patterns of scav-enger cells (reactive microglia).[1]

In 1910 Merzbacher moved to Argentina, where he wasappointed head of the laboratory in the psychiatric clinicat Buenos Aires. From 1914 to 1919 he was in chargeof the department of pathological anatomy at the Clínica

Modelö, and beginning in 1924, was chief physician at the“German hospital” in Buenos Aires.[2]

He is remembered for his pathological studies of a dys-myelinating central nervous system disorder that is nowreferred to as "Pelizaeus-Merzbacher disease" (PMD).[1]This eponymous disease is named along with Germanbalneologist Friedrich Christoph Pelizaeus (1851–1942).Merzbacher described his research of the disorder ina 1910 paper titled Eine eigenartige familiärhereditäreErkrankungform.[3]

1 References[1] Peiffer J, Gehrmann J (July 1995). “Ludwig Merzbacher

(1875-1942): the man behind the disease”. BrainPathology 5 (3): 311–8. doi:10.1111/j.1750-3639.1995.tb00608.x. PMID 8520731.

[2] The Founders of Child Neurology, edited by StephenAsh-wal (biography)

[3] Pelizaeus-Merzbacher disease @ Who Named It

2 External links• Ludwig Merzbacher @Who Named It

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