L’uomo di Similaun (Öetzi)

One of the world's most celebrated human mummies was discovered on September 19th, 1991, at 3270 m above sea level, in the Eastern Alps near the Austro-Italian border. The age of the remains, 5350–5100 years before present, corresponds to the Late Neolithic or the Copper Age.

Report

Complete Mitochondrial Genome Sequence of the

Tyrolean Iceman

•Luca Ermini1, 3, 4, ,Cristina Olivieri1, 4, Ermanno Rizzi2, Giorgio Corti2, Raoul Bonnal2, Pedro Soares3,

•Stefania Luciani1, Isolina Marota1, Gianluca De Bellis2, Martin B. Richards3, Franco Rollo1, ,

•1 Laboratorio di Archeo-Antropologia Molecolare/DNA Antico, Dipartimento di Biologia Molecolare,

Cellulare e Animale, University of Camerino, 62032 Camerino, Italy

•2 Istituto di Tecnologie Biomediche, Consiglio Nazionale delle Ricerche, 20090 Milano, Italy

•3 Institute of Integrative and Comparative Biology, Faculty of Biological Sciences, University of

Leeds, LS2 9JT Leeds, UK

Volume 18, Issue 21, 11 November 2008, Pages 1687–1693

http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542mailto:francougo.rollo@unicam.itmailto:francougo.rollo@unicam.ithttp://www.sciencedirect.com/science/journal/09609822/18/21http://www.sciencedirect.com/science/journal/09609822/18/21http://www.sciencedirect.com/science/journal/09609822/18/21http://www.sciencedirect.com/science/journal/09609822/18/21

Two nucleotide transitions, at positions 16224 and 16311, according to the reference sequence of Anderson et al. [4], were identified, indicating that the Iceman's mtDNA belonged to haplogroup K [5], a subclade of the major west Eurasian haplogroup U [6].

It was found that the Iceman's mtDNA lineage belonged to the K1 subhaplogroup but did not fit with any of the known branches into which the group is presently divided 12, 13, 14 and 15.

http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542http://www.sciencedirect.com/science/article/pii/S0960982208012542

Ötzi, the Tyrolean Iceman belonged to Y-haplogroup G2a4

Questo permette di trarre due conclusioni: gli antenati di Ötzi sono emigrati dal vicino Oriente nel neolitico in seguito alla diffusione dell’agricoltura e dell’allevamento; il loro DNA si è conservato fino a oggi in regioni isolate, come Sardegna e Corsica.

Zink’s team also gathered information about Ötzi’s ancestry. His Y chromosome possesses mutations most commonly found among men from Sardinia and Corsica, and his nuclear genome puts his closest present-day relatives in the same area. Perhaps Ötzi’s kind once lived across Europe, before dying out or interbreeding with other groups everywhere except on those islands.

Genetic informationThe data suggest that Ötzi had brown eyes and type-O blood, and was lactose intolerant. Zink’s team also discovered gene variants linked to hardened arteries, which could help to account for calcium deposits found in scans3. “He wasn’t obese, he was very active, he doesn’t have strong risk factors for developing calcification of his heart,” says Zink. “Perhaps he developed this due to a genetic predisposition.”

http://www.nature.com/news/iceman-s-dna-reveals-health-risks-and-relations-1.10130

14

Ötzi, la mummia del Similaun, intollerante al

lattosio

lunedì 20 gennaio 2014

Oetzi, la mummia del Similaunaveva antenati anche in Sardegna

Aveva occhi marroni, era intollerante al lattosio e aveva probabilmente un antenato in comune con gli attuali abitanti di Sardegna e Corsica: è l'identikit di Oetzi, la celebre mummia del Similaun, ricostruito grazie alla prima mappa completa del suo Dna.

http://edizionedigitale.unionesarda.it/