latest innovations by iita in maize and groundnut value chain

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Date: 15-Oct-2014 www.iita.org A member of CGIAR consortium DFID Latest Innovations by IITA in Maize and Groundnut Value chain – aflasafe TM Lawrence K. Kaptoge Peter Cotty Joseph Atehnkeng Ranajit Bandyopadhyay

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Date: 15-Oct-2014 www.iita.org A member of CGIAR consortium

DFID Latest Innovations by IITA in Maize and

Groundnut Value chain – aflasafe TM

Lawrence K. Kaptoge

Peter Cotty

Joseph Atehnkeng

Ranajit Bandyopadhyay

www.iita.org A member of CGIAR consortium Date: 02 – May - 2013

Out line

• Aflatoxin facts, prevalence in crops and

effects on Human, animal and Trade

• Aflasafe, its development and how it works

• Objectives of the pilot plant

• Large scale manufacture of aflasafe

• Future of aflasafe/ its development in Africa

Date: 15-Oct-2014

• Highly toxic metabolite produced by the ubiquitous Aspergillus flavus fungus

• The fungus infects crops and produces the toxin in the field and in stores

• Fungus carried from field to store

• Contamination possible without visible signs of the fungus

• Some predisposing factors: – pre-harvest high temp and

drought stress

– wet conditions at harvest and

post-harvest periods

– insect damage

Aflatoxin Facts

www.iita.org A member of CGIAR consortium Date: 02 – May - 2013

Prevalence of Aflatoxins in Food & Feed

• Several African staple commodities affected

• High human exposure in Africa – mother to baby

• Levels and frequency of occurrence high

– >30% maize in stores with >20 ppb aflatoxin

– ~90% stores are contaminated with Afla fungi

– Up to 40% grain in households with aflatoxin

• Concern for food and feed processors, government and

emergency food reserve agencies, school-feeding

• Aflatoxins disproportionately impact the poor

• Highly toxic strains, conducive environmental

conditions, traditional farming methods and improper

grain drying and storage practices, unregulated markets

www.iita.org A member of CGIAR consortium Date: 15-Oct-2014

Human and Animal Health Effects

acute

acute hepatic necrosis, cirrhosis,

carcinoma

Death; 200 people in Kenya; 74 in

India

chronic

carcinogenic

stunting in under-fives

anti-nutritional

immune-suppressive

gut integrity?

underreported

unknown

500 ppb AF diet AF-free diet

~40% reduction in live weight (8 weeks)

www.iita.org A member of CGIAR consortium Date: 15-Oct-2014

Trade Losses due to Aflatoxins

• Nigeria and Senegal major groundnut exporters in 1960s. Compliance has economic incentives

Senegal:

• If aflatoxin levels are reduced, then national income would increase by

– $281 million through oil cake export

– $45 million through confectionary groundnut export.

• Best quality exported; poorer quality consumed domestically.

Peanut

Maize

Coffee

Cocoa

Groundnut Pyramids in

Nigeria during 1960s

Pyramids in Egypt?

World Bank; Mbaye (2004)

www.iita.org A member of CGIAR consortium

aflasafe and its development

• Aflasafe is a safe and cost-effective

biocontrol product that reduces aflatoxins in

field and stores

• A. flavus occurs naturally & both toxigenic

and atoxigenic.

• Biological control involves introducing

carefully selected harmless atoxigenic

strains, that have large competitive

advantages over toxic strains .

• competitive exclusion - The atoxigenic

strains virtually eliminate the toxic relatives

and therefore considerably reduce aflatoxin

contamination

Date: 15-Oct-2014

www.iita.org A member of CGIAR consortium Date: 15-Oct-2014

How aflasafe Works

Broadcast

@ 10 kg/ha 2-3 weeks

before flowering

Sporulation on moist soil

Spores

Insects

3-20 days

Wind

aflasafe

Soil

colonization

30-33 grains m-2

Fungal network in killed grain

Farmers treating maize and groundnut fields with AflaSafe

MAIZE: Aflatoxin reduction (%)

Stage 2009 2010 2011

Harvest 82 94 83

Storage 92 93 x

PEANUT: Aflatoxin reduction (%)

Stage 2009 2010 2011

Harvest - 95 82

Storage 100 80 x

71% and 52% carry-over of

inoculum 1 & 2 years after

application

Results from 382

on-farm trials

www.iita.org A member of CGIAR consortium

Development, Effectiveness and Safety of

aflasafe • It was developed by IITA in collaboration with the

Agriculture Research Service of the U.S. Department of

Agriculture, University of Bonn, and University of Ibadan.

• More than 4200 strains of Aspergillus species from naturally

infected maize cobs collected in Nigeria were evaluated.

• 12 safe and effective atoxigenic strains were identified, 4 of

which were further tested.

• Aflasafe can reduce aflatoxin concentration by 60-96% in

maize at harvest and in storage.

• The beneficial effect of aflasafe is carried over from one

season to the next

• It is completely safe. There is no possibility of the four

constituent atoxigenic strains in becoming toxigenic.

• IITA has experience of nearly 50 incident-free person-years

of working on aflatoxin biological control technology that

led to the development of aflasafe. Date: 15-Oct-2014

AF36

Aflaguard

Biocontrol WORKS

In 100’S of thousands of acres in

the US!

IT WORKS In Africa

TOO!

Aflasafe

12

atoxigenic strain manufacturing facility Arizona Cotton Research & Protection Council, USA

AF36 production in USA

www.iita.org A member of CGIAR consortium

Aflasafe Pilot Plant Objectives

Demonstration-scale plant to be used as a model to:

• Optimize and adapt the manufacturing process

• Reduce aflasafe manufacturing cost

• Turn-key facility for replication in other countries

• Demonstrate commercial viability for mass production

of Aflasafe.

Date: 15-Oct-2014

www.iita.org A member of CGIAR consortium Date: 15-Oct-2014

Final Plan

Partition: Labs, Substrate Processing and Packaging/storage of finished product.

Packaging & Finished Product Storage

Wash Rooms

Lab

Grain Intake, Cleaning, Pasteurisation and Storage

www.iita.org A member of CGIAR consortium Date: 15-Oct-2014

Aflasafe Pilot Plant

Workers’ Resting Room

Inoculum Production Lab

Quality Control Lab

Quality Control Lab & Lab office

www.iita.org A member of CGIAR consortium Date: 15-Oct-2014

Aflasafe Pilot Plant

Cooler

Roaster

aflasafe Plant

Aflasafe despatch 2014

www.iita.org A member of CGIAR consortium Date: 15-Oct-2014

Aflasafe Pilot Plant

Weighing & Heat Sealing

Inoculation & Weighing

Finished Product Storage

Final Package – Front & Back

www.iita.org A member of CGIAR consortium Date: 15-Oct-2014

Production 2014

• Production of aflasafe for: • Nigeria – 120 tons

• Senegal – 12 tons

• Zambia – 3 tons

• Mozambique – 1 ton

• Ghana – 1 ton

• Burkina Faso – 2

• Kenya – 2

Inoculum Production

www.iita.org A member of CGIAR consortium

Future and Facts on Aflasafe

• Between 2004-2006, nearly 200 Kenyans died after consuming aflatoxin-

contaminated maize, and in 2010 over 2 million bags of maize were found to

be highly contaminated.

• 99% of infants in Benin and Togo are exposed to aflatoxin-linked health risks.

• Globally, about US$1.2 billion in commerce is lost annually due to aflatoxin

contamination, with African economies losing US$450 million each year.

• IITA has expanded biocontrol research in over 10 countries with products ready

for Burkina Faso, Ghana, Kenya, Mozambique, Senegal, Tanzania and Zambia.

• Adoption of this biocontrol technology with other management practices by

farmers will reduce aflatoxin contamination by more than 70% in maize and

groundnut, increase crop value by at least 25%, and improve the health of

children and women.

• In 2012, G20 leaders launched ‘AgResults’ which includes aflasafe™ as one of

three pilot projects for incentivising adoption of agricultural technologies by the

poor.

• The World Bank estimates that reducing aflatoxin contamination would add

US$281 million annually to Senegalese groundnut exports. Aflasafe-SN01 could

reinstate groundnut exports to the EU lost by Senegal and the Gambia due to

contamination. Source: EIARD by WRENmedia

Date: 15-Oct-2014

www.iita.org A member of CGIAR consortium Date: 15-Oct-2014

Aflasafe Development in Africa

www.iita.org

Products ready for registration

Products under testing in farmers’ fields

Strain development in progress

Aflasafe-NigeriaTM

Aflasafe-SenegalTM

Aflasafe-KenyaTM etc…

Senegal Mali

Burkina

Ghana

Nigeria

Kenya

Tanzania

Mozambique

Zambia

www.iita.org A member of CGIAR consortium Date: 02 – May - 2013