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Analysis, evaluation and conclusion of nutrient content and formulation of three separate multivitamins and assessing the adequacy for a thirty year old male and a twenty year old female as compared to Dietary Reference Intakes (DRI). Utilized Microsoft Excel and Microsoft Word. Kimberly Tierney Bio-Nutrition

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Analysis, evaluation and conclusion of nutrient content and formulation of three separate multivitamins

and assessing the adequacy for a thirty year old male and a twenty year old female as compared to

Dietary Reference Intakes (DRI). Utilized Microsoft Excel and Microsoft Word.

Kimberly Tierney

Bio-Nutrition

Summary of Content

Multivitamin Excel Spreadsheet

Analysis of Three Multivitamin Nutrient Content and Dietary Reference Intake (DRI) of

thirty year old male and twenty year old female

Word Document Interpretation of Data

Analysis of multivitamin content compared to RDA & AI standards

Multivitamin evaluation concentrating on vitamin, macro-mineral, trace mineral, and

electrolyte content

Conclusion

Part 2

Assessing Multi-Vitamin Formulas

_ Vitam

ins &

Min

erals

Vitam

in A

(

Vitam

in C

(mg)

Vitam

in E

(mg)

Vitam

in K

(

Thiam

in (m

g)

Ribofla

vin (m

g)

Niacin

(mg)

Vitam

in B

Vitam

in B

Biotin

(

Pantoth

enic Acid

(mg)

Calcium

(mg)

Iron (m

g)

Phosphoru

s (m

g)

Magn

esium

(mg)

Zinc (

mg)

Manga

nese (m

g)

Chrom

ium

(

Chlorid

e (g)

Potass

ium

(g)

Boron (m

g)

synonym

consists of

compounds; Retinal,

Retinene,

Retinaldehyde,

Retinol, Retinoic

Acid, Carotenoids

Ascorbic Acid,

Dehydroascorbic

Acid, Antiscorbutic

Vitamin

Cholecalciferol,

Calciferol, Calcitriol

α-Tocopherol,

Tocopherols &

Tocotrienols

Phylloquinone,

Menaquinone,

Menadione

Vitamin B₁,

Aneurin Vitamin B₂ Vitamin B₃

compounds:

Pyridoxal,

Pyridoxine,

Pyridoxamine,

5’-Phosphates

Vitamin B₉,

Vit Bc,

Folacin,

Folate,

Pteroylpolyg

lutamates

Cyanocobalamine,

Cobalamine

Vitamin

B₇,

Vitamin H Vitamin B₅

Ferrous

Fumarate,

Ferrous Sulfate,

Ferrous

Gluconate Phosphate

Dietary

Reference

Intakes (DRI)

20 year old

female

Estimated

Average

Requirement

(EAR) 500 60 10 12 0.9 0.9 11 1.1 320 2 800 8.1 580 95 255 6.8 45 700 34

Recommended

Dietary

Allowances

(RDA) &

Adequate

Intakes (AI) 700 75 5 15 90 1.1 1.1 14 1.3 400 2.4 30 5 1000 18 700 150 310 8 55 900 1.8 25 45 2.3 4.7 ND

Tolerable Upper

Limits (ULs) 3000 2000 50 1000 ND ND ND 35 100 1000 ND ND ND 2500 45 4000 1100 350 40 400 10000 11 ND 2000 3.6 none 20

Dietary

Reference

Intakes (DRI)

30 year old

male

Estimated

Average

Requirement

(EAR) 625 75 10 12 1 1.1 12 1.1 320 2 800 6 580 95 330 9.4 45 700 34

Recommended

Dietary

Allowances

(RDA) &

Adequate

Intakes (AI) 900 90 5 15 120 1.2 1.3 16 1.3 400 2.4 30 5 1000 8 700 150 400 11 55 900 2.3 35 45 2.3 4.7 ND

Tolerable Upper

Limits (ULs) 3000 2000 50 1000 ND ND ND 35 100 1000 ND ND ND 2500 45 4000 1000 350 40 400 10000 11 ND 2000 3.6 none 20

1 Multi-

vitamin tablet #1 Amount 3000 200 2.5 20.1 50 10 10 25 10 400 10 300 10 30 5 0 100 70 5 25 500 0.002 50 10 0 0 0.05

Adequate for

Female &

Ranking 1 2 2+2 2 1+2 1 1 1 1 2+1 2 1 1 3+2 2+2 2+2 2+2 2+2 2+2 3+2 2+2 3+2 1 3+2 2+2 2+2

% of RDA met by

Multi-Vitamin 429% 267% 50% 134% 56% 909% 909% 179% 769% 100% 417% 1000% 200% 250% 28% 0% 67% 23% 63% 45% 56% 0% 200% 22% 0% 0%

Adequate for

Male & Ranking 1 2 2+2 2 1+2 1 1 1 1 2+1 2 1 1 3+2 2+2 2+2 2+2 2+2 2+2 3+2 2+2 3+2 1 3+2 2+2 2+2

% of RDA met by

Multi-Vitamin 333% 222% 50% 134% 42% 833% 769% 156% 769% 100% 417% 1000% 200% 250% 63% 0% 67% 18% 45% 45% 56% 0% 143% 22% 0% 0%

Form

natural beta-

carotene

magnesium

ascorbate cholecalciferol

d-alpha

tocopherol phytonadione

thiamine

mononitrate niacinamide pyridoxine HCl cyanocobalamin

D-calcium

pantothenate amino acid chelate

ferrous

bisglycinate from kelp

magnesium

citrate,

magnesium

ascorbate zinc citrate

selenium amino

acid chelate copper oxide

manganese

sulfate

chromium

chloride

sodium

molybdate

potassium

chloride

boron

amino acid

chelate

#2 Amount 300 333 2.5 67 0 10 2 17 10 167 50 50 10 50 0 0 25 50 3 30 333 2 50 20 0 0 0.25

Adequate for

Female &

Ranking 3+2 1 2+2 1 3+2 1 2 3 1 3+2 1 2 1 2+2 3+2 2+2 3+2 3+2 3+2 2+2 3+2 2 1 2+2 2+2 2+2

% of RDA met by

Multi-Vitamin 43% 444% 50% 447% 0% 909% 182% 121% 769% 42% 2083% 167% 200% 5% 0% 0% 17% 16% 38% 56% 37% 111% 200% 44% 0% 0%

Adequate for

Male & Ranking 3+2 1 2+2 1 3+2 1 2 3 1 3+2 1 2 1 2+2 3+2 2+2 3+2 3+2 3+2 2+2 3+2 2+2 1 2+2 2+2 2+2

% of RDA met by

Multi-Vitamin 33% 370% 50% 447% 0% 833% 154% 106% 769% 42% 2083% 167% 200% 5% 0% 0% 17% 13% 27% 56% 37% 87% 143% 44% 0% 0%

Form

beta carotene from

algae calcium ascorbate cholecalciferol

d-alpha

tocopheryl

succinate

thiamin

mononitrate

niacin &

niacinamide pyridoxine HCl cyanocobalamin

di-calcium

pantothenate

di-calcium

pantothenate,

ascorbate from kelp

magnesium

glycinate chelate

zinc glycinate

chelate

L-

selenomethionine

copper

glycinate

chelate

manganese

glycinate

chelate

chromium

glycinate

chelate

molybdenum

glycinate

chelate

potassium

chloride

#3 Amount 1050 90 10 20.1 25 1.5 1.7 20 2 500 6 30 10 200 18 109 150 100 11 55 900 2.3 35 45 0.072 0.08 0.15

Adequate for

Female &

Ranking 2 3 1 2 2+2 2 3 2 2 1 3 3+1 1 1+2 1+1 1+2 1+1 1+2 1 1+1 1+1 1 2 1+1 1+2 1+2

% of RDA met by

Multi-Vitamin 150% 120% 200% 134% 28% 136% 155% 143% 154% 125% 250% 100% 200% 20% 100% 16% 100% 32% 138% 100% 100% 128% 140% 100% 3% 2%

Adequate for

Male & Ranking 2 3+1 1 2 2+2 2 3 2 2 1 3 3+1 1 1+2 1 1+2 1+1 1+2 1+1 1+1 1+1 1+1 2+1 1+1 1+2 1+2

% of RDA met by

Multi-Vitamin 117% 100% 200% 134% 21% 125% 131% 125% 154% 125% 250% 100% 200% 20% 225% 16% 100% 25% 100% 100% 100% 100% 100% 100% 3% 2%

Form not given NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG

vitamins

macrominer

al trace mineral electrolytes below RDA/AI = +2

minimum RDA/AI =

+1 HIGHEST # LOWEST #

Part 2

Assessing Multi-Vitamin Formulas

Boron (m

g)

Nickel (

mg)

Silic

on (mg)

Tin (

Vanad

ium

(mg)

Lute

in (

L-Carn

itine (m

g)

L-Arg

inin

e (mg)

Grape Se

ed Ext

ract

(mg)

Co-Enzy

me Q

10

(mg)

Alpha Li

poic (m

g)

Lyco

pene (mg)

Biofla

vonoid

s (m

g)

Rutin (m

g)

Inosit

ol (m

g)

Hesperid

in (m

g)

Para-a

min

obenzoic

acid (m

g)

Enzym

e Com

plex

(mg)

Proprie

tary

Superfo

od Ble

nd

(mg)

_ __

ND ND ND

1 ND 1.8

ND ND ND

1 ND 1.8

0 0 0 0.008 0 0 0 0 0 0 0 25 10 10 10 75 132 475

Total Ranking 76

Average %

Met 237%

Total Ranking 76

Average %

Met 221%

from

lemon

0 0 0 0 0 25 10 0.8 2.5 2.5 0.25 0 0 0 0 0 0 0

Total Ranking 84

Average %

Met 230%

Total Ranking 86

Average %

Met 219%

L-carnitine

tertrate

L-arginine

HCl

0.005 2 10 0.01 250 0 0 0 0 0 0 0 0 0 0 0 0 0

Total Ranking 58

Average %

Met 111%

Total Ranking 62

Average %

Met 107%

NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG NG

Assessing Multi-Vitamin Formulas

1

The process utilized in the spreadsheet comparing the formulas of three separate multi-vitamins and

assessing the adequacy for a thirty year old male and a twenty year old female progressed as follows.

Initial evaluation included all Dietary Reference Intakes (DRI) incorporating the Estimated Average

Requirement (EAR), Tolerable Upper Limits (UL), and Recommended Dietary Allowances (RDA) and

Adequate Intakes (AI) for comparison and reference of both a twenty year old female and a thirty year

old male.

Analysis of the data detailed in the EAR and AI revealed that in most cases the thirty year old male

necessitates higher concentrations of nutrients than a twenty year old female, but respectively a multi-

vitamin must still meet the RDA and AI for individuals. Specific differences between requirements are

established in the subsequent table:

30 year old males require X% more than

20 year old females in the following:

Chromium 29% Vitamin C 17%

Zinc 27% Riboflavin 15%

Vitamin K 25% Vitamin A 12%

Manganese 22% Niacin 12%

Magnesium 22% Thiamin 8%

*Iron is the exception; A 20 year old female requires 66% more Iron than a 30 year old male.

Men at the age of 30 years should also concentrate on the following vitamins and mineral:

Biotin For hair loss

Boron, Zinc, Vitamin C, Vitamin E and lycopene For prostate health

Zinc, Magnesium, Vitamin B₆ Associated with testosterone

Niacin To ensure healthy cholesterol

Selenium Decreases the risk of cancers; prostate, colon, lung

Women at the age of 20 years should concentrate on the following vitamins and minerals:

Iron and Magnesium Lost during menstruation

Vitamin K Influences healthy intestinal bacteria which in turn aid in absorption, needed more with excessive menstruation

Folic Acid and B₁₂ For the development of the nervous system of a possible future baby

Zinc Metabolism of main nutrients, contributes to immune system function, mental function, fetal growth and reproduction

Assessing Multi-Vitamin Formulas

2

Returning the focus to the analysis of the three multi-vitamins, the interpretation of data began by

converting the units given to corresponding units and serving size. The amounts of each vitamin were

then compared to one another in a several various approaches.

The multi-vitamin’s nutrients that met RDA and AI for females were colored pink on the spread sheet

and males were colored blue. The nutrients that fell below were left uncolored. The amount of each

nutrient in each multi-vitamin was then divided by the RDA and AI to equal the percent met by each

multi-vitamin for the 20 year old female and the 30 year old male separately. These averages will show a

correlation to the average concentrations of each nutrient, higher averages should show higher

concentrations and lower averages should detail lower concentrations throughout the multi- vitamin.

The averages of percentage met by the three multivitamins for the concluded as follows from highest to

lowest concentrations:

Vitamin # Female % Male %

1 237 221

2 230 219

3 111 107

The percentages also revealed which nutrients of each multi-vitamin fell below the RDA and AI as less

than 100% and which met the minimum requirement as 100%. The following table demonstrates the

specifics:

Multi-vitamin

#

Gender Below RDA & AI Total Nutrients

Below

Minimum RDA & AI

Total Nutrients

at Min

Upper Limits

Total Upper Limits

1 Female Vit D, Vit K, Ca, Fe, P, I, Mg, Zn, Cl, K, Se, Cu, Mo, Mn

14 Folic Acid 1 Vit A 1

1 Male Vit D, Vit K, Ca, Fe, P, I, Mg, Zn, Cl, K, Se, Cu, Mo, Mn

14 Folic Acid 1 Vit A 1

2 Female Vit D, Vit K, Vit A, Ca, Fe, P, I, Mg, Zn, Cl, K, Se, Cu, Mo, Folic Acid

15 None None

2 Male Vit D, Vit K, Ca, Fe, P, I, Mg, Zn, Cl, K, Se, Cu, Mo, Mn,

Folic Acid

16 None None

3 Female Vit K, Ca, P, Mg, Cl, K

6 Biotin, I, Se, Cu, Mo, Fe

6 None

3 Male Vit K, Ca, P, Mg, Cl, K

6 Vit C, Biotin, I, Se, Cu, Mo, Zn,

Mn, Cr

9 None

Assessing Multi-Vitamin Formulas

3

The interpretation of the table above concludes multi-vitamin #2 to be lacking the most nutrients for

both male and female, followed closely by multi-vitamin #1. Multi-vitamin #3 is lacking the least in both

male and female nutrients. This evidence is also supported by the number system I devised which would

reveal the complete inclusion of nutrients per multi-vitamin.

The number system compares the three multi-vitamins to one another and ranks each individual

concentration of vitamin, macro-mineral, trace mineral, and electrolyte. The sums will reveal the lowest

total to be the most complete multi-vitamin and the highest total to be insufficient. Each individual

nutrient, such as Vitamin A, of all three multi-vitamins is color coded; highest content being green,

middle as black, and lowest as red. Each nutrient for each gender is assigned a number, highest amount

of the three is given a “1”, second give a “2”, and the lowest amount given a “3.” The multi-vitamin is

also penalized with “+1” for only providing minimum RDA and AI requirements, and “+2” for falling

below requirements. The conclusion of the number system proceeded from lowest to highest, or most

complete to least, as follows:

Vitamin # Female Total Ranking Male Total Ranking

3 58 62

1 76 76

2 84 86

In conclusion of the assessment and different approaches towards analysis of data provided, I found

multi-vitamin #3 to be the most complete for both the 20 year old female and 30 year old male. Multi-

vitamin #3 is the only one of the three to meet the female requirement for Iron. Although its

concentrations aren’t the highest, it is the most inclusive of total nutrients. Second overall inclusive for

both the male and female would be multi-vitamin #1, followed by multi-vitamin #2. Multi-vitamins #1

and multi-vitamin #2 ranked closely in both percent averages and total rank, however, what sets them

apart is how many nutrients in total they are lacking. Multi-vitamin #2 fell short in nearly every analysis

and contained absolutely no Iron. To clarify, I would rank the three multi-vitamins for both male and

female from best to worst as multi-vitamin #3 being the best, then multi-vitamin #1, and worst being

multi-vitamin #2.