khomology nuclear) ribonucleoproteins regulate …遺伝子実験施設セミナー center for gene...

遺伝子実験施設セミナー Center for Gene Research Seminar Nagoya University Khomology nuclear ribonucleoproteins regulate floral organ identity and determinacy in Arabidopsis Speaker: Prof. Antonio Vera Área de Genética Departamento de Biología Aplicada Universidad Miguel Hernández, Spain Date: 2014 July 28 (Mon), 16:00~17:00 Room: F301 (Center for Gene Res. FBldg.) Arabidopsis FLK and PEP encode Khomology proteins similar to human hnRNP K that antagonistically regulate the repressor of flowering time FLC. Now, we show that PEP and FLK collaborate to sustain the floral Cfunction accomplished by another key MADSbox factor, the homeotic gene AG. Genetic and molecular analyses functionally link PEP and FLK to other RNAbinding proteins previously known to regulate AG, and strongly suggest that they participate in a joint gene activity that facilitates premRNA maturation by preventing premature/erroneous processing. Our results define specific morphogenetic roles for PEP and FLK and may reflect their importance for regulatory coupling between different developmental pathways and the multifaceted character of plant KHtype hnRNPs. 連絡先杉田護（内線 3080） [email protected]

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遺伝子実験施設セミナー Center for Gene Research Seminar

Nagoya University

K-‐homology nuclear ribonucleoproteins regulate floral organ identity and determinacy in Arabidopsis

Speaker: Prof. Antonio Vera Área de Genética Departamento de Biología Aplicada Universidad Miguel Hernández, Spain

Date: 2014 July 28 (Mon), 16:00~17:00 Room: F301 (Center for Gene Res. F-‐Bldg.)

Arabidopsis FLK and PEP encode K-‐homology proteins similar to human hnRNP K that antagonistically regulate the repressor of flowering time FLC. Now, we show that PEP and FLK collaborate to sustain the floral C-‐function accomplished by another key MADS-‐box factor, the homeotic gene AG. Genetic and molecular analyses functionally link PEP and FLK to other RNA-‐binding proteins previously known to regulate AG, and strongly suggest that they participate in a joint gene activity that facilitates pre-‐mRNA

maturation by preventing premature/erroneous processing. Our results define specific morphogenetic roles for PEP and FLK and may reflect their importance for regulatory coupling between different developmental pathways and the multifaceted character of plant KH-‐type hnRNPs.

連絡先杉田護（内線 3080） [email protected]

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