• Unpleasant taste• Tooth darkening

• Diarrhea• Constipation

• Pyrosis• Nausea• Vomiting

Side-effects of iron

The low bioavailability of iron leads to higher supplementation doses, thus resulting in increased adverse effects.

Ca

Fe

Ca

FeFe

AB-Fortis® can help overcome the challenges

Mouth:• Minimum contact with iron• No metallic taste, no tooth darkening, and good palatability (small particle size)

Stomach: • Acid pH, low release of iron Stomach and intestine: • Use of Fe(lll) salt with fewer adverse effects

Adequate compliance:• Reduced adverse effects Iron efficiency:• Increased bioavailability

Intestine:• Bioavailability enhanced by chelation

+ High bioavailabilitybut- Metallic taste

- Reactive, carrier oxidation (e.g. rancidity of lipids)

Soluble iron salts

Meat

Vegetarian meat analogues

Cereals

+ No taste

+ Iron is not reactive

+ Controlled release: high bioavailability

Encapsulated soluble iron salt

Global # affected in millions

• Preschool-age children

• Pregnant women

• Non-pregnant women

293.1

56.4468.4

Cognitive performance in children and increased tiredness in women

Impaired psychomotor development

Microencapsulatediron salt

High concentration of iron (40%)

No metallic taste or negative

interactions

High stability Cost effective

Bioavailability confirmed by

published human study

Results of comparative study: AB-Fortis® equally bioavailable as FeSO4

-3,0

-2,0

-1,0

0,0

1,0

2,0

3,0

4,0

5,0

6,0

Baseline 0h 1h 2h 3h 4h 5h 6h

Incr

eas

e in

Tra

nsf

err

in S

atu

ratio

n (

%)

Control AB-Fortis

Meat and Savoury

Milk, yoghurtVegetarian proteins

and meat alternatives

Bakery

Gummies& candy

DrinksDairy

IRON NEVER TASTED SO GOOD

MICROENCAPSULATED IRON

Iron deficiency is a global health problem affecting around a billion people

Iron fortification and supplementationface many challenges

&

of people in developed countries

Affects around

20%

in some developing countries

Up to

60%

Data from WHO report: The global prevalence of anaemia in 2011

Iron deficiency is a global health problemMore prevalent in children under 6 years oldand in women of childbearing age

Introducing AB-Fortis®: Encapsulated soluble iron salt with patented microencapsulation technologyProviding highly stable encapsulation that prevents the release of free iron in the food matrix

Data from WHO report: The global prevalence of anaemia in 2011

Contreras et al. European Journal of Nutrition 2013

Mostly associated with:

+ No taste

+ Iron is not reactive: minimal oxidation of the carrierbut

- Bioavailability is low or non-existing

Insoluble iron salts

AB-Fortis® can be used in many food applications

AB-Fortis® has a bioavailability equivalent to that of ferrous sulphate

AB-Fortis® = easy iron supplementation and fortification