1. Invest in Toronto Region: Accelerate Innovation toDrive Competitive AdvantageApril 2010 TORONTO REGION RESEARCH ALLIANCEwww.trra.ca

2. Breakthrough InnovationInsulin (1921)Stem Cells (1961) Blackberry (1999)www.trra.ca 3. Pivotal North American Location www.trra.ca 4. Key Facts7.4 million people 4th largest urbancentre in North America $349 Billion GDP 64% of population 25-64 with post-secondary education 79,700 science & technology workplaces(308,000 overall) 30% of Canadas most highly-citedscientistsSources: Environics Analytical Group 2010; Conference Board of Canada, 2007; ISI, 2010www.trra.ca 5. Exceptional InfrastructurePublicly supported, integrated transit systems100% digital telecom infrastructure2 Major rail carriers7 Major highways6 Airports with 79 carriersLargest, electronically cleared container facility in the Great Lakeswww.trra.ca 6. Magnet for Innovative Companiesv www.trra.ca 7. Substantial R&D Investment Canadian Headquarters in Toronto RegionR&D Expenditure Rank Company$000 FY2008 CDNMagna International693,000 3IBM Canada 397,000 5Research in Motion 384,000 6Atomic Energy of Canada Ltd. 329,000 7Apotex 219,000 9GlaxoSmithKline Inc. (Canada)150,000 13Ericsson 126,000 14Open Text Corporation113,000 17Aastra Technologies Limited105,000 18Biovail99,00023AstraZeneca Canada 89,00025Source: Research InfoSource 2009www.trra.ca 8. Why the Toronto Region?Global StatusTop TalentOutstanding R&DCompetitive CostsAdvanced EconomyAttractive Lifestyle www.trra.ca 9. Global Status 10. Hub of Leading ClustersNumber of key strategic clusters in whichToronto Region ranks in the top 5 in North AmericaLos Angeles 22Chicago 20Toronto Region 18New York18 Boston7Dallas 7 Toronto Region Top Clusters San Jose5 Houston 4#2 Automotive Detroit 3#2 Food ProductionPhiladelphia 3#2 Financial ServicesSources: (US) ISC Harvard 2007, (Canadian) Institute of Competitiveness and Prosperity Canadian Cluster Data 2006 www.trra.ca 11. On the Rise and Connected to the World Broadband Penetration, G7 Countries through June 2009 35CanadaGermany 30France25Unit ed KingdomUnit ed St at es20JapanOECD15It alySource : 10 5 0 2001- 2002- 2002- 2003- 2003- 2004- 2004- 2005- 2005- 2006- 2006- 2007- 2007- 2008- 2008- 2009-Q4Q2Q4Q2Q4Q2Q4Q2Q4Q2Q4Q2Q4Q2Q4Q2Source: OECD 2010 www.trra.ca 12. Top Talent 13. Best Educated Population in the WorldPercentage of Population with Post-Secondary Education (25 to 64 years of age)80% 64%60% 40% 20%0%ToRuCa JaUS UK FrGeIta rossian ad paAanrm lyn toancean Re n Fe y gi o denrati on Sources: Statistics Canada, 2006; OECD Education at a Glance, 2007 www.trra.ca 14. Most Ethnically Diverse RegionOver 100 languages andmajor dialects60% of immigrants have atleast one university degreeConnected to business andscience worldwide Source: Statistics Canada, 2006; City of Torontowww.trra.ca 15. Continually Renewed Pool of Skilled Workers 87,000 Graduates /Year47,000 Immigrants /Yearwith University Degree1.8 Million Workers with University Degrees or College Diplomas (25-64 Years) Sources: Statistics Canada, 2006; Common University Data Ontario, 2009 www.trra.ca 16. Leading Region for Top ScientistsNumber of Highly Cited Scientists Per Million PeopleSwitzerland 15.14United States12.98Toronto Region7.96 Sweden6.89Israel6.73 Netherlands6.31Denmark5.66 Canada5.72Australia 5.44Germany3.18France 2.60 Japan2.08Austria 2.38Ireland1.74Italy1.43 United 1.05 Source: ISI, 2009www.trra.ca 17. Outstanding R&D 18. World-Leading Research and Education 9 Universities 12 Academic Hospitals 8 Institutes of Technology and Colleges Over 300 Research Institutes 320,000 Full-Time Students 87,000 Graduating Students per Year 11,450 Faculty Members Sources: Common University Data Ontario, 2010; Ministry of Training, Colleges and Universities, 2006www.trra.ca 19. Advanced Research CollaborationsExamples Include: Canadian Institute for Advanced Research Guelph Molecular Super Centre MaRS Discovery District Ontario Centres of Excellence Ontario Institute for Cancer Research Perimeter Institute for Theoretical Physics Sheridan Science and Technology Park www.trra.ca 20. Canadian Institute for Advanced ResearchGlobally recognized Located in the heart of Toronto International, trans-disciplinary research collaborations Over 300 of the worlds top scientists from 13 countries 14 Nobel Laureates 12 Research Programs 1,400 post-graduateswww.trra.ca 21. MaRS Discovery District750,000 sf innovation centre in downtownToronto focused on creating and growing anew generation of technology companiesThe MaRS Centre co-locates 65organizations and 2,000 people from: Multinational companies Public research labs Technology start-ups Venture capital firms Professional services firms Technology transfer offices Regional associations and networks Over $350 million in funding from theprivate sector, the Governments of Ontarioand Canada, and university and regionalstakeholderswww.trra.ca 22. Ontario Institute for Cancer Research$142 million funding by the Government ofOntario Toronto based Modeled after the Broad Institute atHarvard and MIT Multi-disciplinary and multi-institutionalcollaboration Supports over 50 internationallyrecognized researchers across theprovince Led by Dr. Tom Hudson, world-leadinggenomics researcherwww.trra.ca 23. Perimeter Institute for Theoretical PhysicsWorld leading foundational theoretical physics research instituteLocated in the thriving city of Waterloo$175 million endowment42 resident researchers300-plus visiting scientists per yearShared knowledge agreements with 30 universities worldwidewww.trra.ca 24. Advanced Research Resources Examples Include:Automotive Centre of Excellence atUniversity of Ontario Institute ofTechnologyCanada Centre for Electron Microscopyat McMaster UniversityOntario Tumour BankORION/CANARIE high bandwidthnetworksPositron Emission Tomography Centre atthe Centre for Addiction and MentalHealthThe University of Toronto StructuralGenomics Consortium www.trra.ca 25. Canadian Centre for Electron Microscopy$ 18 million facility with most advanced suite of electron microscopes in the worldShared vision of almost 90 researchers across CanadaKey component of national nanoscience strategyOpened in June 2007 at Brockhouse Institute for Materials Science at McMaster University www.trra.ca 26. ORION/CANARIE high bandwidth networks ORION Leading-edge network for Ontarios research community Spans 5,800 km to 21 cities in Ontario Electronic resources for faculty and students Access to almost 10 million articles from over 7,600 research journals CANARIE Links ORION users to researchers across Canada and around the world Worlds first national, user-controlled, optical Internet research and education network www.trra.ca 27. Competitive Costs 28. Competitive Operating Costs for R&D Low Operating Costs for Research and Development Toronto 95.8Raleigh 96.4 Dallas97.7 Houston97.9Chicago98.8 Paris100.1 Boston 100.8 San Diego100.9 London 101.7New York City102Frankfurt 103.6 Tokyo108.9 95100105 110Cost Index: 100 = US Average Source: KPMG Competitive Alternatives 2010www.trra.ca 29. Lowest Expenditure on Health Care as a Percentage of GDP in G7 (2007) Ontario7.6 70% of health care costs Japan 8.1 in Canada are publicly- funded compared to 45%United Kingdom8.4 in the United States.Italy8.7 Canada 10.1 Germany 10.4France 11.0 United States 16.0 Sources: OECD Health Data 2008, www.investinontario.com, 2009 www.trra.ca 30. Lower Corporate Income Taxes (% of income)Ontario 32.0% North Carolina41.9% New York 42.1%Illinois42.3% Indiana43.5%Massachusetts 43.8% California 43.8% Pennsylvania 45.0% Sources: Deloitte Quick Facts 2008, Federation of Tax Administrators 2010, OECD Tax Database 2009 www.trra.ca 31. Exceptional R&D Tax Credits*France 123.9Canada 100Japan 85.9U.K.84U.S.80.6Italy77Germany76.1*Index Canada = 100Source: Think Canada March 2010www.trra.ca 32. Favourable Cost of Living Toronto 70.9 Index = 100 (New York)Chicago 80.7 Los Angeles87.6London 92.7Paris95.1Shanghai 95.2 Singapore98 New York100Hong Kong 108.7Tokyo 143.7 Source: Mercer Cost of Living Survey, 2009 www.trra.ca 33. Additional SupportGrants and loansOntario Advanced Manufacturing Investment Strategy (AMIS)Ontario Market Readiness ProgramOntario Biopharmaceutical Investment Program (BIP)Ontario Next Generation of Jobs FundFederal Industrial Research Assistance Program (IRAP)Federal Sustainable Development Technology CanadaFederal Technology Partnerships Canada Other SupportRegional Innovation Centres and Sector Innovation CentresOntario Centres of ExcellenceIndustry Liaison Initiatives by Universities, Colleges, Institutes ofTechnology, and Hospitalswww.trra.ca 34. Advanced Economy 35. Large Multi-Sectored EconomyResilient to business cycles Exceptional support services Cross-sectoral scope and synergy Large talent pools in critical staff areas Magnet for knowledge and creativity www.trra.ca 36. Leading the Convergence of R&D Clusters Photonics Robotics Electronics Medical devicesEnvironmental technologies AdvancedMedical imaging Nanotechnology Manufacturing BiomaterialsQuantumcomputing Stem cell researchICT BIO Cryptography Drug development Digital Media BiomarkersWirelessHealth informaticsProteomics Agri-Foodwww.trra.ca 37. Attractive Lifestyles 38. Appealing Lifestyle Options Safe environmentVibrant arts and cultureExceptional sports and recreationGreat variety of urban, suburban and rural communities www.trra.ca 39. Leadership and Commitment The Hon Dalton McGuinty, PremierCourtney Pratt TRRA Founding Co-Chairs:ChairmanMr. Gordon Nixon, CEO, RBC Financial GroupToronto Region Research Alliance Dr. John Evans, Chair, MaRS Discovery District (TRRA Launch October 2005)www.trra.ca 40. TRRA offers R&D Investors1. Key information and data2. Quick access to regional leadership (governments,business and institutions)3. Reliable navigation and introductions to the most relevantregional resources www.trra.ca 41. Lets Get Started . Global StatusTop TalentOutstanding R&DCompetitive CostsAdvanced EconomyAttractive Lifestyles www.trra.ca 42. Why Invest in Toronto Region? Click to play embedded video www.trra.ca 43. For more information, contact us: Toronto Region Research AllianceMaRS Centre, Heritage Building 101 College Street, Suite HL30 Toronto, ON M5G 1L7Email: info@trra.caTel: 1 416 673 6674Fax: 1 416 673 6671www.trra.cawww.trra.ca