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Integrating Science, Dialogue, and Stewardship for Forest Biotechnology CFS – LFC Seminar Series November 15, 2012 Susan McCord [email protected]

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Integrating Science, Dialogue, and Stewardship for Forest Biotechnology

CFS – LFC Seminar Series November 15, 2012 Susan McCord [email protected]

Everyone Loves Trees!

Trees are Different

Characteristics Food Crops / Croplands Trees / Forests

Lifespan Months years Decades centuries

1 Breeding cycle 1 year or less Multiple years

Pollen spread Dozens of Km Hundreds of Km

Wildlife habitat & refuge Low High

CO2 sequestration potential Low High

H20 Cleansing Low High

Food calorie production High Low

Global acreage 1.6 billion hectares 3.9 billion hectares

Hunting, hiking, camping, exploring

Not often Yes!

Why Biotech Trees?

Forests are under extreme pressures ✓ Invasive threats ✓ Human population growth and demands ✓ Land converted out of forestry ✓ Climate change, biofuels, illegal logging,

global trade pressure...

Bottom Line: Unsustainable demands on current forests

When Used Responsibly Forest Biotechnology Might:

Protect species: a mechanism to bring threatened and endangered species back to forest ecosystems

Conserve land: growing more wood on less land, rehabilitating degraded soils

Fight a changing climate: withstand weather extremes and sequester more carbon to reduce greenhouse gas concentrations

Improve biofuels: increase the sustainability and efficiency of producing forest fuels

Grow more wood: more than double wood production, improve wood quality

Clean up after us: systematically absorb and store toxic substances from the environment for safe disposal.

The IFB

Established in 2001 as a non-profit

Global in scope

Neutral approach to technology

Board reflects stakeholder groups

Funding sources: ~ ½ Non-profit, ¼ Government, ¼ Industry

Stakeholder Engagement

Assessments of forest biotechnology in Europe, North America, and Latin America

Begin discussion on ecological risk assessment

IFB Projects Science

Heritage Trees Forest Health Initiative*

Pine Genome Initiative

Dialogue

Forest Fuels

Stewardship

Responsible Use Principles

*Project Secretariat

Science: Forest Biotechnology and Forest Health

CFS – LFC Seminar Series November 15, 2012 Susan McCord - [email protected]

Forest Health Initiative

A useful model for: Engaging both sides of the tree biotech

debate in a positive and productive way Outreach and stakeholder collaboration Working successfully with regulatory

agencies Cooperative research agendas Demonstrating social & environmental

benefit

Forest and Urban Trees under Attack

Conifers

Ash Elms

The American Chestnut: Icon to Oblivion

Blight killed 4 BILLION trees Food for animals and people Fast growing, high quality

lumber Wildlife habitat

Forest Health Initiative Structure

Three year project Exploring biotechnology as a tool for forest health Created as a response to multiple threats

Funding:

Steering Committee U.S. Forest Service U.S. Endowment for Forestry and Communities Duke Energy Environmental Defense Fund The Nature Conservancy

Benefits & Challenges

Benefits Identify survival traits Insert survival traits Fast replication

Challenges Technical hurdles Environmental impacts Regulatory approval for transgenics Social acceptance

Neutral Space to Consider Biotech

Engage Broad Group of Stakeholders

Give Equal Weight to “Open Minded” Skeptics

Public Benefit Project

Braided Approach

Diverse Voices on Advisory Panels

Convene Series of Forums and Webinars

FHI Biotechnology Research

Genome sequence

Collection & coordination

Population genotyping

Early screen development

Vegetative propagation

Transgenics

complete parts list ~35,000 genes

Comparisons help identify important genes

Genomics – Chestnut Sequence

Vs

• Information exchange among centers

- to integrate current activities - to foster innovation

• Germplasm exchange for clonal testing

SUNY-ESF at Syracuse (Bill Powell, Chuck Maynard) Pennsylvania State University (John Carlson, Webb Miller) University of Georgia (Scott Merkle, Joe Nairn) USDA-FS SIFG (Dana Nelson)

Science Team Centers (Contact PIs)

Germplasm - Coordination

Populations

Chromosome segments

Genes

Determine origins of blight resistance

Integration of sequencing data to inform breeding programs

Germplasm – Population Genotyping

Current method • One embryo, one tree

• 5-7 years to screen

Clonal method • One embryo, many trees

• Earlier screen

Clonal Testing – Propagation & Screening

Agrobacterium Chestnut PEMs Embryos

Feasibility has been established

• Blight resistance candidate genes in the pipeline

• Candidate genes from Chinese chestnut are being discovered

Clonal Testing – Transgenic Lines

Established Field Testing Sites of Transgenic Lines

740 transgenic trees and 534 controls

Somatic seedlings with FHI CGs for Phytophthora resistance will be ready for screening in 2013

4-year-old tree, inoculated with the blight to evaluate resistance level after several months. PA-TACF http://www.patacf.org/patacfactivities.htm

Traditional stem assay vs. leaf assay

Traditional assays: 2 3 1

4 5 6

Leaf assays can be done with 6 or more leaves with results in 3 to 7 days.

Savings of ~ 4 years!

IFB Led the Regulatory & Policy Effort

1. Open lines of communication with policy stakeholders 2. Engage a wide spectrum of additional stakeholders

Phase 1 Start 5 years prior to use

Phase 2 Start 3-5 years prior to use

Phase 3 Start 3-1 years prior to use

Chart 2 - Relevant Patent Holders of Constructs 3. Review intellectual property

4. Assemble a biological dossier 5. Review regulatory landscape

6. Query agencies to define a regulatory course 7. Prepare an environmental report 8. Interact with agencies on future regulations

Social & Environmental Committee

The Nature Conservancy Society of American Foresters Conservation Fund Environmental Defense Fund The American Chestnut Foundation National Parks Service and others….

Forest Health Roadmap

Dialogue: Forest Biotechnology and Mobile Applications

CFS – LFC Seminar Series November 15, 2012 Susan McCord - [email protected]

Smart Phone Application

TreeTaggr is a citizen scientist app designed to enable individuals to report information related to tree diseases, parasites, and other environmental stresses.

Completion Funds ~$30K

TreeTaggr Development

02/2012 02/2013

Initial Scoping

✓ Database*

✓ API* ✓ Detailed Scoping

✓ Phone

Software ($20,000)

Website Front-end ($10,000)

* Work done in Canada

• Free to any user • Open source code • Database custom built for geographic analysis • Leaderboard encourages use and learning • Plan to capture 90% of smartphones with GPS

1. Android 2. iPhone 3. Windows phone

TreeTaggr.org

Stewardship: Forest Biotechnology and Certification Systems

CFS – LFC Seminar Series November 15, 2012 Susan McCord - [email protected]

SFM Systems and Biotech Trees

PEFC : Programme for Endorsement of Forest Certification

International Banned / Precautionary approach based on lack of data

FSC : Forest Stewardship Council International Banned / Precautionary approach based on lack of data

CerFlor : Certificação Florestal Brazil Banned via PEFC registration / No additional rationale

CertFor : Certficación Forestal Chile Banned via PEFC registration / No additional rationale

SFI : Sustainable Forestry Initiative N. America Banned via PEFC registration / Awaiting risk-benefit data

ATFS : American Tree Farm System USA Banned via PEFC registration / No additional rationale

CSA : Canadian Standards Association Canada Banned via PEFC registration / Allows public to determine

approach

CFCC : China Forest Certification Council China Banned via PEFC registration / No additional rationale

Responsible Use Initiative

• Phase 1, 3 years • Global stakeholder

input • Committee of

international experts

• Transparent process

• Phase 2, started 2012

Biotech Tree Value Chain

• NOT a certification system • Voluntary and easy to use • Global in scope • Transparency is critical: responsibleuse.org • Multistakeholder interaction

Principles are Globally Relevant

Bridge SFM gaps

Principles can be modified by users

Individual components can be adopted

Addresses some key stakeholder issues: Transparency Governance Stakeholder engagement Communication

Join the Forest Biotechnology Partnership: http://www.forestbiotech.org/partners.html

Subscribe to IFB’s news feed: http://forestbiotech.org/news

Join IFB’s Linked-In group: www.forestbiotech.org/linkedin

Adam Costanza Susan McCord [email protected] [email protected]

FORESTBIOTECH.ORG

IFB Resources