integrating evidence-based practice into qi to improve patient outcomes in hiv: viral load...
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Integrating Evidence-Based Practice Into QI to Improve Patient Outcomes in HIV: Viral Load Suppression
Victoria Lieb, ACRN, MPH; Carla Rossi, MD; Jaime Bloss, CRNP, MSN; Christa DeLong, MA; Rebecca Haffner, MA; & Kailly Muthard, MSW
Background & Purpose
Viral load (VL) suppression is key to both improving patient outcomes in HIV and to decreasing community viral load. Patient adherence to antiretroviral therapy (ART) is crucial in achieving VL suppression and preventing viral resistance.
The Easton Community HIV/AIDS Organization (ECHO), a Ryan White Part C program in eastern Pennsylvania, began to participate in the National Quality Center’s In+Care program in October 2011. Viral Load (VL) Suppression is defined by In+Care as a VL <200 copies/ml.• ECHO Baseline VL Suppression Rate: 67%• National Benchmark Data:
81.9% (top 25%) 86.5% (top 10%).
Goals of ECHO’s quality improvement project: • Increase the percent of patients with a
suppressed viral load • Incorporate evidence-based practices into
patient care• Develop standardized processes for the
management of unsuppressed patients
Evidence-Based Strategies Utilized
• Individualized patient-centered approach • Adherence assessments by phone or in
person for unsuppressed patients conducted by RN within 2 weeks
• Motivational interviewing techniques utilized in adherence counseling
• Adherence tools: alarmed pill boxes, cell phone alarms, phone call reminders, office-based pill box refills, and frequent phone call follow-up.
• Brief adherence intervention during yearly wellness visits.
MethodsWe convened a multidisciplinary team (MD, NP, RN, CM, MA’s) which:• Conducted a literature search to
determine best practices • Utilized DHHS guidelines and IAPAC
guidelines• Completed process flow diagrams for
clinical & non-clinical processes • Incorporated evidence-based strategies
into an adherence program• Developed an algorithm for clinical
management of unsuppressed patients
ResultsViral load suppression increased 19%, from 67% of all patients to 79%.
Conclusions
An individualized, patient-centered approach incorporating evidence-based clinical guidelines is effective in achieving viral load suppression for many patients. We developed a clinical management guideline based on Department of Health and Human Services (DHHS) guidelines and adherence guidelines published by the International Association of Physicians in AIDS Care (IAPAC) and other published studies. Our results indicate that a combination of current clinical practice guidelines and adherence counseling which utilizes motivational interviewing techniques can help patients to improve and maintain adherence to ART.
Oct 20
11
Dec 20
11
Feb 2
012
Apr 20
12Ju
ne 20
12
Aug 20
12
Oct 20
12
Dec 20
12
Feb 2
013
Apr 20
13
Jun 2
013
Aug 20
13
Oct 20
13
60%62%64%66%68%70%72%74%76%78%80%
67%
69%
73%
75%
74%
75%
77%
75%
79%
77%
73%
79%
Easton Community HIV Organization Percent of Patients with Suppressed Viral Load
October 2011 - October 2013
Formulate & Implement
Adherence Plan
2nd VL >200
Adherence Assessment at Next
Appointment
Recheck VL in 3 months
or less
2nd VL <200
Adherence Assessment by
phone or in-person within 2 weeks
Viral Load < 200 Viral Load > 200
Adherence Issues
Identified
No Adherence
Issues
No Adherence
Issues
Consider /Do Genotype
Consider/Do Tropism & HLAB5701
Evaluate for Drug-Drug Interactions
Consider/ Make Med
Easton Community HIV/AIDS OrganizationGuideline for Management of Unsuppressed
Viral Load
Ongoing Adherence Monitoring and VL
Testing at 2-3 Month Intervals Until Undetectable
Routine VL Monitoring Every 3-4 Months
ReferencesInternational Association of Physicians in AIDS Care. (2012). Guidelines for improving entry into and retention in care and antiretroviral adherence for persons with HIV: evidence-based recommendations from an International Association of Physicians in AIDS Care Panel. Retrieved from Agency for Healthcare Research and Quality website: http://www.guideline.gov/content.aspx?id=36947&search=iapacInternational Association of Physicians in AIDS Care website. (n.d.). http://www.iapac.org/AboutUs01.html
Panel on Antiretroviral Guidelines for Adults and Adolescents. (2012). Guidelines for the use of antiretroviral agents in HIV-1 infected adults and adolescents. Retrieved from AIDSinfo website: http://www.aidsinfo.nih.gov/contentfiles/guidelines/adultandadolescentgl.pdf
Rollnick, S., Miller, W., & Butler, C. (2008). Motivational interviewing in health care. New York, NY: Guilford .
Simoni, J. M., Amico, R., Pearson, C., & Malow, R. (2008). Strategies for promoting adherence to antiretroviral therapy: A review of the literature. Current Infectious Disease Reports, 10, 515-521.
Adherence Counseling Using Motivational Interviewing Techniques (OARS)
Open-Ended Questions: “It’s hard for many people with HIV to take their medications. So tell me how you find that it’s going for you.”Affirmations: “You’ve done really well over the past year in coming to appointments and getting your lab work done.”Reflective Listening: “It sounds like you’re trying to juggle a lot of things right now and sometimes it’s hard for you to remember to take your pills.”Summaries: “ You’ve had to deal with some unexpected things in your personal life lately that have kind of taken your focus off of taking good care of yourself., But you’re willing to try some new things to help you remember to take your medicines and to keep in contact with us more frequently over the next several months until you’re back on track. Let’s check back in a month and see how it’s going.”