importance of soluble fiber in treating diabetes

4
STAY HEALTHY INFO  We Promote Four Pillars of Health    Good Nutrition, Regular Exercise, Adequate Rest, Positive Attitude http://facebook.com/stay.healthy.info [email protected] Importance of Soluble Fiber in Treating Diabetes http://www.konjacfoods.com/fiber.htm  Diabetes is a disease in which the body is unable to produce insulin (type 1), cannot produce enough insulin (type 2), or has become insulin resistant (type 2). Insulin is a hormone that lets cells know when they should absorb blood glucose (sugar) to burn for energy. Without the proper functioning of insulin, blood glucose increases to dangerously high levels. Fortunately, scientists have shown that soluble fibers such a s konjac glucomannan may slow insulin response and the rise in blood glucose levels after a meal [1,5,6,7,8,11,13,14,15,16,19,20,21], as well as reduce blood cholesterol [3,6]. In addition, soluble fiber may help diabetic patients lose weight [4,12,17,18,22] and improve the health of their colons [9,10]. Dietary fiber is defined as the complex carbohydrates from plants that humans lack the enzymes to digest. Fiber is divided into two categories: soluble and insoluble. Whereas insoluble fiber passes through the digestive tract relatively unchanged, soluble fiber dissolves to form a soft gel. Although insoluble fiber is an important component of healthy diets, this article focuses on soluble fiber because of its special characteristics as related to diabetes. Pectins, gums, and mucilages are examples of soluble fiber. Some familiar foods that contain soluble fiber are apricots, citrus, oats, lentils, and dried beans and peas. The most important qualities of soluble fiber are viscosity and fermentability. Viscosity refers to the thickness of a solution and its resistance to flow. Soluble fiber binds 20-200 times its weight in water, becoming a viscous, slow-moving solution. Fermentability refers to the di gestion of soluble fiber by “friendly” bacteria inhabiting the intestines. These bacteria produce beneficial chemicals and fecal matter. Not all soluble fiber is fermentable. However, bacteria in the digestive tract depend on soluble fiber in order to flourish and ward off infections of “hostile” bacteria. Blood Glucose & Insulin Sensitivity  Many diabetic patients keep track of the glycemic index of their foods. Foods with a high glycemic index, such as processed starches and the sugar in soft drinks, break down into glucose and enter the bloodstream relatively quickly. Unrefined, complex carbohydrates, on the other hand, have a low glycemic index and digest more slowly. Diabetic patients should consume food with a low glycemic index because rapid increases in blood glucose exacerbate overproduc tion of insulin by the pancreas and insulin resistance. Since they both affect the rapidity with which blood glucose rises after a meal, soluble fiber and foods with a low glycemic index confer similar benefits. During digestion, wave-like currents caused by contractions of the intestinal muscles bring nutrients to the surface of the intestinal wall for absorption. After soluble fiber dissolves in water, however, it traps nutrients inside its gummy gel and slows down considerably while moving through the digestive tract. Inside the gel, nutrients are shielded from digestive enzymes and less likely to reach the wall of the intestines. Dietary sugars like carbohydrates and starch are among the nutrients trapped inside this gel. Consequently, sugar is absorbed into the bloodstream more slowly, blunting the sharp spike in blood glucose t ypically experience d by diabetic patients after a meal. Fewer spikes in blood glucose lead to greater sensitivity to the action of insulin. Avoiding high peaks and low valleys in blood glucose places less stress on the pancreas and i s important not only to diabetics but also to those who want to prevent the development of type 2 diabetes.

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Page 1: Importance of Soluble Fiber in Treating Diabetes

8/7/2019 Importance of Soluble Fiber in Treating Diabetes

http://slidepdf.com/reader/full/importance-of-soluble-fiber-in-treating-diabetes 1/4

STAY HEALTHY INFO

 We Promote Four Pillars of Health  –  

Good Nutrition, Regular Exercise, Adequate Rest, Positive Attitude 

http://facebook.com/stay.healthy.info  [email protected] 

Importance of Soluble Fiber in Treating Diabetes

http://www.konjacfoods.com/fiber.htm 

Diabetes is a disease in which the body is unable to produce insulin (type 1), cannot produce enough insulin

(type 2), or has become insulin resistant (type 2). Insulin is a hormone that lets cells know when they should

absorb blood glucose (sugar) to burn for energy. Without the proper functioning of insulin, blood glucose

increases to dangerously high levels. Fortunately, scientists have shown that soluble fibers such as konjac

glucomannan may slow insulin response and the rise in blood glucose levels after a meal

[1,5,6,7,8,11,13,14,15,16,19,20,21], as well as reduce blood cholesterol [3,6]. In addition, soluble fiber may

help diabetic patients lose weight [4,12,17,18,22] and improve the health of their colons [9,10].

Dietary fiber is defined as the complex carbohydrates from plants that humans lack the enzymes to digest.

Fiber is divided into two categories: soluble and insoluble. Whereas insoluble fiber passes through the

digestive tract relatively unchanged, soluble fiber dissolves to form a soft gel. Although insoluble fiber is animportant component of healthy diets, this article focuses on soluble fiber because of its special

characteristics as related to diabetes. Pectins, gums, and mucilages are examples of soluble fiber. Some

familiar foods that contain soluble fiber are apricots, citrus, oats, lentils, and dried beans and peas.

The most important qualities of soluble fiber are viscosity and fermentability. Viscosity refers to the

thickness of a solution and its resistance to flow. Soluble fiber binds 20-200 times its weight in water,

becoming a viscous, slow-moving solution. Fermentability refers to the digestion of soluble fiber by

“friendly” bacteria inhabiting the intestines. These bacteria produce beneficial chemicals and fecal matter.

Not all soluble fiber is fermentable. However, bacteria in the digestive tract depend on soluble fiber in order

to flourish and ward off infections of “hostile” bacteria.

Blood Glucose & Insulin Sensitivity 

Many diabetic patients keep track of the glycemic index of their foods. Foods with a high glycemic index,

such as processed starches and the sugar in soft drinks, break down into glucose and enter the bloodstream

relatively quickly. Unrefined, complex carbohydrates, on the other hand, have a low glycemic index and

digest more slowly. Diabetic patients should consume food with a low glycemic index because rapid

increases in blood glucose exacerbate overproduction of insulin by the pancreas and insulin resistance. Since

they both affect the rapidity with which blood glucose rises after a meal, soluble fiber and foods with a low

glycemic index confer similar benefits.

During digestion, wave-like currents caused by contractions of the intestinal muscles bring nutrients to thesurface of the intestinal wall for absorption. After soluble fiber dissolves in water, however, it traps nutrients

inside its gummy gel and slows down considerably while moving through the digestive tract. Inside the gel,

nutrients are shielded from digestive enzymes and less likely to reach the wall of the intestines. Dietary

sugars like carbohydrates and starch are among the nutrients trapped inside this gel. Consequently, sugar is

absorbed into the bloodstream more slowly, blunting the sharp spike in blood glucose typically experienced

by diabetic patients after a meal. Fewer spikes in blood glucose lead to greater sensitivity to the action of 

insulin. Avoiding high peaks and low valleys in blood glucose places less stress on the pancreas and is

important not only to diabetics but also to those who want to prevent the development of type 2 diabetes.

Page 2: Importance of Soluble Fiber in Treating Diabetes

8/7/2019 Importance of Soluble Fiber in Treating Diabetes

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STAY HEALTHY INFO

 We Promote Four Pillars of Health  –  

Good Nutrition, Regular Exercise, Adequate Rest, Positive Attitude 

http://facebook.com/stay.healthy.info  [email protected] 

Scientists propose one other explanation for soluble fiber’s effect on blood glucose. In order for nutrients to

be absorbed into the intestines, they must first cross an unstirred water layer covering the surface of the

intestines. Soluble fiber thickens this layer, making it more resistant to the movement of nutrients diffusing

into the body. Both theories attempt to explain why blood glucose levels rise more slowly when consumed

with soluble fiber.

Blood Cholesterol 

The link between high blood cholesterol and poor heart health is well-known. Patients with type 2 diabetes,

approximately 90% of whom are obese, are at an especially high risk for heart disease. Therefore, it is

important to combat diabetes on multiple fronts, not only by watching blood glucose levels but blood

cholesterol levels as well. Fortunately, soluble fiber has been shown to lower blood cholesterol, including

LDL cholesterol. Some evidence suggests that soluble fiber makes LDL particles less dense and, therefore,

less harmful.

Besides trapping fat and cholesterol that would otherwise be digested by the body, there are two proposed

mechanisms for the lowering of blood cholesterol by soluble fiber. In the first scenario, soluble fiber traps

bile acids in the same way that it traps sugars and carries them out of the body as waste. Bile acids are

produced from cholesterol in the liver. Therefore, if bile acids are removed, the body pulls cholesterol from

the bloodstream to produce more.

In the second theory, soluble fiber shifts the bile acid pools away from cholic acid and toward another acid

(chenodeoxycholic acid) that inhibits an enzyme involved in fat and cholesterol production (3-hydroxy 3

methylglutaryl CoA reductase). Decreased enzyme activity means less cholesterol produced by the liver and

lower blood cholesterol levels.

Weight Management 

Few aspects of health are more important to a diabetic patient than weight management. The overwhelming

majority of diabetic patients are obese. Frustratingly, obese people are at a higher risk for insulin resistance,

yet insulin resistance leads to fat storage. For this reason, many patients struggle to maintain a healthy

weight.

Soluble fiber helps dieters in several ways. First, foods containing soluble fiber typically take more time to

consume and are more enjoyable to chew. Second, the stomach empties more slowly, causing greater

feelings of fullness and fewer cravings. Third, it “soaks up” some of the calories in a meal by trapping

nutrients in its gel so that it is harder for them to be absorbed before leaving the body as eliminated waste.

Colon Health 

Many people who develop type 2 diabetes are obese because of poor nutrition, putting their colons at risk.

Soluble fiber makes stool softer and easier to pass, which means less constipation and fewer hemorrhoids.

Helpful microorganisms in the intestines feed on 70-80% of dietary soluble fiber and are very important for

overall health. If intestinal bacteria are fed properly, they become plentiful and widespread, spreading

throughout the GI tract. Increased bacterial production causes increased fecal mass.

Page 3: Importance of Soluble Fiber in Treating Diabetes

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STAY HEALTHY INFO

 We Promote Four Pillars of Health  –  

Good Nutrition, Regular Exercise, Adequate Rest, Positive Attitude 

http://facebook.com/stay.healthy.info  [email protected] 

The products of fermentation are primarily lactate and short-chain fatty acids, most commonly acetic,

butyric, and propionic acids. Short-chain fatty acids aid in the proliferation of mucosal cells that produce

mucus for lubrication. They are sources of energy and increase water and sodium absorption. A fatty acid

gel moisturizes stool as well as nourishes and protects the intestinal lining of the intestines. Short-chain fatty

acids also contribute to glucose metabolism, which may confer additional benefits to diabetic patients.

Greater Viscosity, Greater Effect 

The most valuable attribute of soluble fiber is viscosity. The slower and thicker the gel, the better. Tabatabai

and Li from Rush Presbyterian-St. Luke's Medical Center in Chicago note [16], “Viscosity of the dietary

fiber is important; the greater the viscosity, the greater the effect.” Some fibers produce a more viscous

solution than others. For example, guar is more viscous than xanthum, which is more viscous than psyllium.

Konjac Glucomannan 

While many sources of soluble fibers are beneficial, konjac roots bear the distinction of containing konjac

glucomannan (KGM), the most viscous soluble fiber in nature. The extraordinary properties of KGM make

it an ideal example of soluble fiber’s effectiveness in improving diabetic health. KGM has the highest 

molecular weight of all known dietary fibers and is able to hold more water than any other fiber. In food

production, it is a versatile ingredient. It can be used as an excellent thickening or stabilizing agent. KGM is

even hardy enough to transform into pasta and noodles in a variety of sizes and shapes.

As a fiber supplement, konjac powder can be taken easily with water before meals, e.g. 1 tsp. dissolved in 1

cup water. The fiber immediately forms an observable gel. Konjac powder has produced promising results in

clinical studies for the treatment of diabetes[6,7,8,11,13,14,15,16,19,20,21]. For example, McCarty writes in

Medical Hypotheses, “Administration of 4-5g of GM with meals, blended into fluid or mixed with food, canslow carbohydrate absorption and dampen the postprandial [after-meal] insulin response by up to 50%.

Controlled clinical studies document that GM can promote satiety and weight loss [4,12,17,18,21], lower

LDL cholesterol, improve diabetic control, and correct constipation, with minimal if any side-effects.” 

References 

1.  Aller R, de Luis DA, Izaola O, La Calle F, del Olmo L, Fernandez L, Arranz T, Hernandez JM.

Effect of soluble fiber intake in lipid and glucose levels in healthy subjects: a randomized clinical

trial. Diabetes Res Clin Pract. 2004 Jul;65(1):7-11. 

2.  Arjmandi BH, Ahn J, Nathani S, Reeves RD. Dietary soluble fiber and cholesterol affect serum

cholesterol concentration, hepatic portal venous short-chain fatty acid concentrations and fecal sterolexcretion in rats. J Nutr. 1992 Feb;122(2):246-53. 

3.  Arvill A, Bodin L. Effect of short-term ingestion of konjac glucomannan on serum cholesterol in

healthy men. Am J Clin Nutr. 1995 Mar;61(3):585-9.

4.  Biancardi G, Palmiero L, Ghirardi PE. Glucomannan in the treatment of overweight patients with

osteoarthritis. Curr Ther Res. 1989 Nov;46(5):908-12.

5.  Chandalia M, Garg A, Lutjohann D, von Bergmann K, Grundy SM, Brinkley LJ. Beneficial effects

of high dietary fiber intake in patients with type 2 diabetes mellitus. N Engl J Med 2000 May

11;342(19):1392-1398. 

Page 4: Importance of Soluble Fiber in Treating Diabetes

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STAY HEALTHY INFO

 We Promote Four Pillars of Health  –  

Good Nutrition, Regular Exercise, Adequate Rest, Positive Attitude 

http://facebook.com/stay.healthy.info  [email protected] 

6.  Chen HL, Sheu WH, Tai TS, Liaw YP, Chen YC. Konjac supplement alleviated

hypercholesterolemia and hyperglycemia in type 2 diabetic subjects--a randomized double-blind

trial. J Am Coll Nutr. 2003 Feb;22(1): 36-42.

7.  Doi K. Effect of konjac fibre (glucomannan) on glucose and lipids. Eur J Clin Nutr 1995 Oct;49

Suppl 3: S190-7

8.  Gonzalez Canga A, Fernandez Martinez N, Sahagun AM, Garcia Vieitez JJ, Diez Liebana MJ, Calle

Pardo AP, Castro Robles LJ, Sierra Vega M. [Glucomannan: properties and therapeutic

applications.] Nutr Hosp. 2004 Jan-Feb;19(1):45-50. Spanish.

9.  Homann HH, Kemen M, Fuessenich C, Senkal M, Zumtobel V. Reduction in diarrhea incidence by

soluble fiber in patients receiving total or supplemental enteral nutrition. J Parenter Enteral Nutr.

1994 Nov-Dec;18(6):486-90. 

10. Hopman WP, Houben PG, Speth PA, Lamers CB. Glucomannan prevents postprandial

hypoglycaemia in patients with previous gastric surgery. Gut. 1988 Jul;29(7):930-4.

11. Jenkins DJ, Kendall CW, Axelsen M, Augustin LS, Vuksan V. Viscous and nonviscous fibres,

nonabsorbable and low glycaemic index carbohydrates, blood lipids and coronary heart disease. CurrOpin Lipidol 2000 Feb;11(1):49-56.

12. Livieri C, Novazi F, Lorini R. [The use of highly purified glucomannan-based fibers in childhood

obesity.] Pediatr Med Chir. 1992 Mar-Apr;14(2):195-8. Italian. 

13. McCarty MF. Glucomannan minimizes the postprandial insulin surge: a potential adjuvant for

hepatothermic therapy. Med Hypotheses. 2002 Jun;58(6):487-90. 

14. Melga P, Giusto M, Ciuchi E, Giusti R, Prando R. Dietary fiber in the dietetic therapy of diabetes

mellitus. Experimental data with purified glucomannans. Riv Eur Sci Med Farmacol. 1992 Nov-

Dec;14(6):367-73. 

15. Shima K, Tanaka A, Ikegami H, Tabata M, Sawazaki N, Kumahara Y. Effect of dietary fiber,

glucomannan, on absorption of sulfonylurea in man. Horm Metab Res. 1983 Jan;15(1):1-3. 

16. Tabatabai A, Li S. Dietary fiber and type 2 diabetes. Clin Excell Nurse Pract 2000 Sep;4(5):272-6. 17. Vido L, Facchin P, Antonello I, Gobber D, Rigon F. Childhood obesity treatment: double blinded

trial on dietary fibres (glucomannan) versus placebo. Padiatr Padol. 1993;28(5):133-6.

18. Vita PM, Restelli A, Caspani P, Klinger R. [Chronic use of glucomannan in the dietary treatment of 

severe obesity.] Minerva Med. 1992 Mar;83(3):135-9. Italian. 

19. Vorster HH, De Jager J. The effect of the long-term ingestion of konjac-glucomannan on glucose

tolerance and immunoreactive insulin values of baboons. S Afr Med J. 1984 May 19;65(20):805-8.

20. Vuksan V, Jenkins DJ, Spadafora P, Sievenpiper JL, Owen R, Vidgen E, Brighenti F, Josse R, Leiter

LA, Bruce-Thompson C. Konjac-mannan (glucomannan) improves glycemia and other associated

risk factors for coronary heart disease in type 2 diabetes. A randomized controlled metabolic trial.

Diabetes Care. 1999 Jun;22(6):913-9.

21. Vuksan V, Sievenpiper JL, Owen R, Swilley JA, Spadafora P, Jenkins DJ, Vidgen E, Brighenti F,Josse RG, Leiter LA, Xu Z, Novokmet R. Beneficial effects of viscous dietary fiber from Konjac-

mannan in subjects with the insulin resistance syndrome: results of a controlled metabolic trial.

Diabetes Care. 2000 Jan;23(1):9-14.

22. Walsh DE, Yaghoubian V, Behforooz A. Effect of glucomannan on obese patients: a clinical study.

Int J Obes. 1984;8(4):289-93.