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By Stephen Elgert, MD W hen patients have upper respiratory infections, they often ask their family doctors “How can I boost my immune system so I won’t get sick?” As a family doctor, I hear patients list various over-the-counter products and natural or health store items wondering if the promises advertised will work. Mega doses of vitamins, mushroom extracts, garlic, selenium, Echinacea and other herbs often top most lists in products that are touted to strengthen the immune response. Unfortunately, there is little to no actual evidence that these help prevent or cure upper respiratory infections. Some may, in fact, be harmful or interfere with other prescribed medications. Antibiotics are also often not helpful in viral illnesses unless some secondary complications such as otitis media (ear aches caused by bacterial infections) occur. The concept of immune boosting itself poses problems. The immune system is complex and often responds in unexpected ways when confronted with a foreign invader such as a cold virus. Doctors often paradoxically need to give medications that actually DECREASE the immune response to adequately treat disease. One example of this is asthma. Susceptible individuals who get cold viruses (respiratory synctial virus is a good example) have a cascade of events that in the end lead to excess inflammation and ultimately bronchospasm (constriction of airways) that is typical of an asthma attack. Doctors often respond by using either oral or inhaled steroids and other medications to decrease these symptoms. Another example of this is severe forms of infectious mononucleosis (mono) and cases of severe sinusitis. Both occasionally require therapy to reduce the body’s over reactive immune response (which is commonly called inflammation) with steroids and other medications. So if “boosting” your immune system is not all that helpful, what else can be done to avoid or treat common colds? Certainly flu vaccine is a good starting point and should be considered every fall season, not just by high-risk individuals, but also for all. People should also wash their hands thoroughly and frequently and cover up when sneezing or coughing. Adequate sleep and stress reduction techniques to lessen anxiety and other psychological factors can play a role. Good nutritional intake is important to maintain health. Finally, a recent study showed some value in zinc supplements for treating cold symptoms although more research needs to be done to determine the right dose and preparation for this purpose. Avoiding colds and flu is a goal we all want to achieve. Family Physicians can often help guide you in your quest to stay healthy and avoid unnecessary exposures. Dr. Elgert has been an Assistant Professor in Family Practice at Dartmouth Medical School and the University of Michigan Medical School, and was most recently affiliated with Dartmouth Family Practice in Concord, NH. Dr. Elgert is a graduate of Rutgers Medical School, and holds a Master of Science degree in Quality Improvement. He can be reached at Elliot Family Medicine at Bedford Village, Independence Place, 15 Constitution Drive, Suite 214, Manchester, 603-472-7233. IMMUNE BOOSTING IMMUNE BOOSTING

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Page 1: IMMUNE BOOSTING - Elliot Hospitalelliothospital.org › _wmur › Articles › Immune Boosting.pdfimmune response (which is commonly called inflammation) with steroids and other medications

By Stephen Elgert, MD

When patients have upper respiratory infections, theyoften ask their family doctors “How can I boost my

immune system so I won’t get sick?” As a family doctor, I hearpatients list various over-the-counter products and natural or healthstore items wondering if the promises advertised will work. Megadoses of vitamins, mushroom extracts, garlic, selenium, Echinaceaand other herbs often top most lists in products that are touted tostrengthen the immune response. Unfortunately, there is little to noactual evidence that these help prevent or cure upper respiratoryinfections. Some may, in fact, be harmful or interfere with otherprescribed medications. Antibiotics are also often not helpful inviral illnesses unless some secondary complications such as otitismedia (ear aches caused by bacterial infections) occur. The concept of immune boosting itself poses problems. Theimmune system is complex and often responds in unexpected wayswhen confronted with a foreign invader such as a cold virus.Doctors often paradoxically need to give medications that actuallyDECREASE the immune response to adequately treat disease.One example of this is asthma. Susceptible individuals who getcold viruses (respiratory synctial virus is a good example) have acascade of events that in the end lead to excess inflammation andultimately bronchospasm (constriction of airways) that is typical ofan asthma attack. Doctors often respond by using either oral orinhaled steroids and other medications to decrease these symptoms.Another example of this is severe forms of infectiousmononucleosis (mono) and cases of severe sinusitis. Bothoccasionally require therapy to reduce the body’s over reactiveimmune response (which is commonlycalled inflammation) with steroids andother medications.

So if “boosting” your immune system is not all that helpful,what else can be done to avoid or treat common colds? Certainlyflu vaccine is a good starting point and should be considered everyfall season, not just by high-risk individuals, but also for all. Peopleshould also wash their hands thoroughly and frequently and coverup when sneezing or coughing. Adequate sleep and stress reductiontechniques to lessen anxiety and other psychological factors canplay a role. Good nutritional intake is important to maintainhealth. Finally, a recent study showed some value in zincsupplements for treating cold symptoms although more researchneeds to be done to determine the right dose and preparation forthis purpose. Avoiding colds and flu is a goal we all want to achieve. FamilyPhysicians can often help guide you in your quest to stay healthyand avoid unnecessary exposures.

Dr. Elgert has been an Assistant Professor inFamily Practice at Dartmouth Medical Schooland the University of Michigan Medical School,and was most recently affiliated withDartmouth Family Practice in Concord, NH.Dr. Elgert is a graduate of Rutgers MedicalSchool, and holds a Master of Science degree in Quality Improvement. He can be reached

at Elliot Family Medicine at Bedford Village, Independence Place, 15 Constitution Drive, Suite 214, Manchester, 603-472-7233.

IMMUNE BOOSTING

IMMUNE BOOSTING