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Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13:1991 Orlando, Florida, USA October 31 - November 3, 1991 EDITED BY Joachim H. Nagel William M. Smith 91CH3068-4 Part 4/5 Biophysical and Biochemical Measurements, Sensors, Lasers and Electrooptics, Molecular Electronics, Instrumentation, Critical Care Monitoring, Rehabilitation Engineering, Speech, Hearing, and Vision Aids THIS PART CONTAINS: Track 8: Biophysical and Biochemical Track 9: Biosensors _ f uNIVERSITATSBSBUOTHEK Track 14: Critical Care Monitoring I HANNOVER Track 18: Instrumentation 1 Track 19: Lasers and Electrooptics I TECHN1SCHE Track 23: Molecular Electronics | INFORMATIONSBIBUOTHEK^ Track 31: Rehabilitation Engineering Track 33: Speech, Hearing and Vision Aids Track 3 5: Technology for the Agin g

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Page 1: IEEE Engineering BiologySociety · 2008. 7. 15. · Part3: Track13: ComputersinMedicine 1040-1257 Track 17: ExpertSystems inMedicine 1258- 1348 Track21: MedicalInformatics 1349- 1392

Proceedings of the Annual International Conference

of the

IEEE Engineering in Medicine and Biology Society

Volume 13:1991

Orlando, Florida, USA • October 31 - November 3, 1991

EDITED BY

Joachim H. NagelWilliam M. Smith

91CH3068-4

Part 4/5

Biophysical andBiochemical Measurements, Sensors, Lasers andElectrooptics, Molecular Electronics,

Instrumentation,Critical CareMonitoring,

Rehabilitation Engineering, Speech, Hearing, and Vision Aids

THIS PART CONTAINS:

Track 8: Biophysical and Biochemical

Track 9: Biosensors_ f uNIVERSITATSBSBUOTHEK

Track 14: Critical Care Monitoring IHANNOVER

Track 18: Instrumentation 1

Track 19: Lasers and Electrooptics I TECHN1SCHE

Track 23: Molecular Electronics | INFORMATIONSBIBUOTHEK^Track 31: Rehabilitation EngineeringTrack 33: Speech, Hearing and Vision Aids

Track 3 5: Technology for the Agin g

Page 2: IEEE Engineering BiologySociety · 2008. 7. 15. · Part3: Track13: ComputersinMedicine 1040-1257 Track 17: ExpertSystems inMedicine 1258- 1348 Track21: MedicalInformatics 1349- 1392

PROCEEDINGS EMBS1991

Proceedings of the 13th Annual International Conference

of the IEEE Engineering in Medicine and Biology Society"New Frontiers of Biomedical Engineering - Innovations from Nuclear to Space Technology"Orlando, Florida, USA • October 31 - November 3,1991

OVERVIEW BY TRACKS Part Pages

Track 1: Aerospace Applications 5 1940 -1961

Track 2: Bioelectric Phenomena 2 0496 - 0562

Track 3: Bioengineering in Dentistry 1 0327 -0355

Track 4: Bioengineering Education 5 2348 -2366

Track 5: Biomaterials 3 1474- 1481

Track 6: Biomechanics 5 1962 - 2042

Track 7: Biomedical Applications of Automatic Control 5 2141 -2184

Track 8: Biophysical and Biochemical Measurements 4 1482 - 1559

Track 9: Biosensors 4 1560-1632

Track 10: Cardiovascular Mechanics 5 2043 -2140

Track 11: Clinical Engineering 5 2367-2385

Track 12: Computed Tomography 1 0001 - 0059

Track 13: Computers in Medicine 3 1040 - 1257

Track 14: Critical Care Monitoring 4 1633 -1669

Track 15: Electrocardiography 2 0563-0832

Track 16: Electromagnetic Interactions 2 0950 - 1039

Track 17: Expert Systems in Medicine 3 1258 -1348

Track 18: Instrumentation 4 1670- 1741

Track 19: Lasers and Electrooptics 4 1742 - 1780

Track 20 Magnetic Resonance Imaging 1 0060 - 0128

Track 21: Medical Informatics 3 1349- 1392

Track 22: Medical Ultrasound 1 0129 - 0200

Track 23: Molecular Electronics 4 1781 -1802

Track 24: Neural Networks 3 1393-1473

Track 25: Neuromuscular Systems 2 0833 - 0949

Track 26: Nonlinear Dynamics in Biomedical Engineering 5 2185 - 2243

Track 27: Positron Emission Tomography 1 0201 -0228

Track 28: Physiological Imaging 1 0229 - 0326

Track 29: Physiological Modeling 5 2244-2331

Track 30: Processing of Biological Signals 1 0356-0495

Track 31: Rehabilitation Engineering 4 1803- 1872

Track 32: Sleep and Respiratory Control Dynamics 5 2332 - 2347

Track 33: Speech, Hearing, and Vision Aids 4 1873- 1931

Track 34: Health Care Technology and Alternate Therapy 5 2386 - 2397

Track 35: Technology for the Aged 4 1932 -1939

4 — iv

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EMBS1991 PROCEEDINGS

OVERVIEW BY PARTS

Part 1: PagesTrack 12: Computed Tomography 0001 -0059

Track 20 Magnetic Resonance Imaging 0060 - 0128

Track 22: Medical Ultrasound 0129 - 0200

Track 27: Positron Emission Tomography 0201 - 0228

Track 28: Physiological Imaging 0229-0326

Track 3: Bioengineering in Dentistry 0327 - 0355

Track 30: Processing of Biological Signals 0356 - 0495

Part 2:

Track 2: Bioelectric Phenomena 0496-0562

Track 15: Electrocardiography 0563 - 0832

Track 25: Neuromuscular Systems 0833 - 0949

Track 16: Electromagnetic Interactions 0950 - 1039

Part 3:

Track 13: Computers in Medicine 1040-1257

Track 17: Expert Systems in Medicine 1258- 1348

Track 21: Medical Informatics 1349- 1392

Track 24: Neural Networks 1393 - 1473

Track 5: Biomaterials 1474 - 1481

Part 4:

Track 8: Biophysical and Biochemical Measurements 1482 - 1559

Track 9: Biosensors 1560 - 1632

Track 14: Critical Care Monitoring 1633 -1669

Track 18: Instrumentation 1670 - 1741

Track 19: Lasers and Electrooptics 1742- 1780

Track 23: Molecular Electronics 1781 - 1802

Track 31: Rehabilitation Engineering 1803 - 1872

Track 33: Speech, Hearing, and Vision Aids 1873- 1931

Track 35: Technology for the Aged 1932-1939

Part 5:

Track 1: Aerospace Applications 1940 - 1961

Track 6: Biomechanics 1962 - 2042

Track 10: Cardiovascular Mechanics 2043 - 2140

Track 7: Biomedical Applications ofAutomatic Control 2141 -2184

Track 26: Nonlinear Dynamics in Biomedical Engineering 2185 - 2243

Track 29: Physiological Modeling 2244-2331

Track 32: Sleep and Respiratory Control Dynamics 2332 - 2347

Track 4: Bioengineering Education 2348 - 2366

Track 11: Clinical Engineering 2367-2385

Track 34: Health Care Technology and Alternate Therapy 2386 - 2397

4-v

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Table of Contents EMBS 1991

Part 4/5

Biophysical and Biochemical Measurements, Sensors, Lasers and Electrooptics, Molecular Electronics,

Instrumentation,

Critical Care Monitoring,Rehabilitation Engineering, Speech, Hearing, and Vision Aids

Track 8: Biophysical and Biomedical Measurements

Session 1. Genetics and Protein Engineering and Biochemical Measurements

8.1-1: A New Classification of Amino Acid Residues by Using Machine Learning Approach 1482

H.G. Alnahi, Dept. of Electrical Engineering, Brunei University, Uxbridge, England

8.1-2: A Model-Based Estimation of DNA Synthesis Rate from Bivariate DNA-BrdU Distribution 1485

A. Bertuzzi, A. Gandolfi and G. StaraceMst. di Analist del Sistemi ed Informatica del CNR, *Ist. di Medicina

Sperimentale del CNR, Roma, Italy

8.1-3: Computer Assisted Design of Purine Nucleoside Analogs: Implications in Aids-Therapy 1487

P.N. Yadav, J. Yadav*, C. Wong, S. Laxrainarayan* and M.J. Modak, Dept. of Biochemistry and Molecular

Biology, *Academic Computer Center, University of Medicine and Dentistry of New Jersey, Newark, NJ

8.1-4: Searching for Regulatory Signals in DNA Sequences: the Nuclear tRNA Genes Example 1488

W. Makalowski, Dep. of Biopol. Biochem., Poznan University, Poznan, Poland

8.1-5: Hardware-Based Comparison of DNA Sequences 1490

E.A. Cheever, M.L. Wennemyr*. W.A. Karunaratne and D.B. Searls**, Dept. of Engineering, Swarthmore Coll.,

Swarthmore, PA., "Thayer Sch of Engin., Dartmouth Coll., Hanover, NH, **Unisys Center, Paoli, PA

8.1-6: Anesthesine Modified Polysacharides. I. Synthesis and Characterization 1492

C.V. Uglea, A. Apetroaie, I. Elena and I.I. Negulescu*, Inst, of Biological Researches, Iassy, Romania, *

Louisiana State Univ., Baton Rouge, LA

Session 2. New Frontiers in Radiation Protection

8.2-1: DNA Supercoiling, Radiation Sensitivity and Radioprotectant Modifier 1494

C.E. Swenberg, J.M. Speicher and C.F. Loss, Dept. of Radiation Biochemistry, Armed Forces RadiobiologyResearch Institute, Bethesda, MD

8.2-2: Radiation Protection and Platelet Aggregation Inhibition 1496

H. Wang, X. Li, Y. Chen, L. Yuan, and W.O. Foye*, Inst, of Radiation Medicine, Shanghai Medical University,Shanghai, P.R. China,* Mass. College of Pharmacy and Allied Health Sci., Boston, MA

8.2-3: The Pharmacokinetics of Ethiofos (WR-2721) and WR-1065 in the Rhesus Monkey, A 1498

Noncompartmental ApproachL, Fleckenstein, N.F. Swynnerton, R.S. Geary, B.K. Huelle, M.A. Miller and D.J. Mangold, Dept. of

Pharmacology, Walter Reed Army Inst, of Research, Washington, DC and SW Research Inst., San Antonio.TX

8.2-4: Recent Radioprotective Compounds 1500

H.A. Musallam, Walter Reed Army Institute of Research, Washington, DC

8.2-5: Relationship Between EJras Expression and Radiation Resistance in Human Osteosarcoma 1501

Cells

A.C. Miller, D. Samid*, K. Kariko, and E.P. Clark, Armed Forces Radiobiology Research Institute,* Uniformed

Services University of The Health Sciences, Bethesda, MD

8.2-6: Electrical Noise Investigation on Reduced and Oxydized Glutathione 1504

M.-A. Rix-Montel, E.L.M. Mouhyidtne, and D. Vasilescu, Laboratoire de Btophysique, Universite de Nice, Nice,France

Session 3. Visual System Measurements

8.3-1: Modeling of Electroretinogram and its Relation to Stimulus Light IntensityJ.J. Castro, A.U. Meyer* and E.J. Haupt**, Dept. of Elect. & Comp. Engr., N.J. Inst, of Tech., *Dept. of

Ophthalmology, Eye Inst, of NJ **Dept. Psychology, Monclair State Coll., NJ

1506

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Table of Contents EMBS 1991

8.3-2: Study of Diffrequencies "Surmounting" Disparities 1509

J. Xu and J. Ge, Dept. of Biological Science and Technology, Zhejiang University, Hangzhou, Zhejiang, P.R.China

8.3-3: Automatic Extraction of Human Corneal Endothelium Cell Contours 1511

G. Cazuguel, J.P. Rannou and F. Mimouni*, Dept. de Mathematique et Systemes de Communication, EcoleNationale Supereure des Telecomm,, Brest, France, *Service DAVIEL, Univ. Morvan, Brest, France

8.3-4: High Dimensional Chaos of Miniature Eye Movements 1513

H. Yoshimatsu and M. Yamada, ATR Auditory and Visual Perception Research Lab., Kyoto, Japan

Session 4. Measurements and Validation in Cardiac Research

8.4-1: Validation of a Computer Controlled Experimental Set-Up for Studying the Process of 1516

ThrombolysisA.-M, Nilsson, B. Olsson and B. Johansson, Dept, of Cardiology, University Hospital, Lund, Sweden

8.4-2: Laser Doppler Study of a Model of Intracardiac Jet: Implications for in Vivo Color Doppler 1518

Ultrasound

B. Diebold, A. Delouche, Ph. Delouche, Ph. Dumee and P. Peronneau, Unite INSERM, Hospital Broussais,

Paris, France

8.4-3: Three Dimensional Ultrasonic Micrometer for Use in Cardiovascular Research 1520

W. Smith and I. Vesely, The John P. Robarts Res. Inst, and The Dept. of Elect. Engr., University of Western

Ontario, London, Ont., Canada

8.4-4: Impedance-Cuff Plethysmography: Application for the Evaluation of Peripheral Vascular 1522

DynamicsH. Shimazu, A Kawarada, H. Kobayashi, M. Akimoto and H. Ito, Dept. of Physiology, Kyorin University School

of Medicine, Tokyo, Japan

8.4-5: A Real-Time Heart Beat Interval Collection, Display and Analysis System 1524

R. dePaola, K.M. Elliott, J.D. Breen and W.I. Norwood, Div. of Cardiothoracic Surgery, The Children's Hospitalof Philadelphia, Philadelphia, PA

Session 5. Channel Dynamics and Membranes

8.5-1: Differential Inhibition of Sodium Currents by Divalent Cations in AtT-20//D16-16 Clonal 1526

Anterior Pituitary Cells

R.E. Sheridan and M. Adler, Neurotoxicology Branch, United States Army Medical Research Inst, of Chemical

Defense, Aberdeen Proving Ground, MD

8.5-2: Construction of Cardiac Sodium Current Based on Membrane Action Potentials 1528

M. Shtrakawa, S. Usui, T. Anno*, A. Taniguchi* and J. Toyama*, Dept. of Information & Computer Sci.,

Toyohashi Univ.of Tech,, Toyohashi, * Res. Ins. of Environmental Medicine, Nagoya Univ., Nagoya, Japan

8.5-3: Review of Data Analysis Methodologies in the Study of Ionic Channel Dynamics 1531

P. Jasthi, S. Laxminarayan*, G.J, Huang**, J. McArdle**, and P. Engler, Biomed. Engr. Center, New Jersey

Inst, ofTechnology, *Div. of Academic Comp. and **Dept. of Pharmacology, Univ. of Med. and Dent, of New

Jersey, Newark, NJ

8.5-4: LB Films as a Model System for Photosensitizers in Membranes 1532

B. Ebert, T. Hanke*, M. Kohl, U. Sukowski, R. Haseloff*,D. Naether**, B. Roeder** and H. Rinneberg,

Physlkalisch-Tech. Bundesanstalt,*Inst. of Molecular Biology, **Dept. of Physics, Humboldt Univ., Berlin,

Germany

8.5-5: Entropy Transduction on Photoinduction 1534

T.K. Basak, Elect. Engr. Dept., Jadavpur University, Calcutta, India

8.5-6: Neurotransmitter-Gated Ion Channels as Molecular Sites of Psychactive Drug Action 1536

F.F. Weight, R.W. Peoples, D.M. Lovinger, G.W. White, L.G. Aguayo, C. Li and S. Visentln, National Institute

on Alcohol Abuse and Alcoholism, Rockville, MD

Session 6. Biophysical Measurements

8.6-1: Magnetometric Study of Interaction of Phagosomes and Microfilaments 1538

I. Nemoto, K. Koide and N. Imano, Tokyo Denki University Hatoyama, Saitama, Japan

8.6-2: Temperature-Rise Characteristics in Phantom Exposed to a Pair of Opposing Magnetic Fields at 1539

13.56 MHz

S. Nishide and S. Ueno*, Kurume College of Technology, Kurume, *Dept. of Electronics, Kyusyu University,Fukuoka, Japan

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Table of Contents EMBS 1991

8.6-3: A Laser Magnet Immunoassay with Ultra High Sensitivity for Direct Antigen Detection

K. Arishima, T. Hoshino, K. Fujiwara, S. Shibata, M. Suzuki* and H, Mizutani*, NTT Opto-electronics Lab.,

*Dept. of Virology, Kanto Teisin Hospital, Tokyo, Japan

8.6-4: Mapping of Brain Potentials

G. Ravindran and K.P. Manimala, School of ECE, College of Engr., Guindy, India

8.6-5: Biochemical Systems Theory Applied to the Human Red-Blood Cell

T.-C. Ni and M.A. Savageau, Dept. of Microbiology and Immunology, University of Michigan, Ann Arbor, MI

8.6-6: A New Encephalomagnetic Effect Generated in Static Magnetic Fields of NMR

L. von Klitzing, Dept. Clin. Research, Medical University Luebeck, Luebeck, Germany

Session 7. Measurement Devices and Analysis Techniques

8.7-1: Some Recent Developments in the in Vivo Analysis of Body Elements and Body CompositionJ. Dutton, C.J. Evans, W.D. Morgan*, D. Rassi, S.JiS. Ryde*, N.H. Saunders, A. Sivyer*, Univ. College of

Swansea, UK, *Singleton Hospital, Swansea, UK

8.7-2: Electrical Impedance Techniques for the Monitoring of Water Balance in Brain

Yu. E. Moskalcnko, M.V. Vorobyev, and G.B, Weinstein, Inst, of Evolutionary Physiology and Biochemistry,

Academy of Sciences USSR, Leningrad, USSR

8.7-3: A Passively Q-Switched ND: Yag Laser for the Treatment of the Eyes with High MyopiaR. Dabu, B. Carstocea*, M. Burcea*, C. Fenic, A. Stratan and 1. Lancranjan, Institute of Atomic Physics,Central Military Hospital, Bucharest

8.7-4: Method of the Cornea Radius Estimation with a Surgical MicrotelemanipulatorS. Hayat, Centre d'Automatique de Lille, Villeneuve dAscq, France

8.7-5: Study of Kidney off-Body Being Kept in Existence

J. Ge, G, Shen, Y. Xu, J. Zhang and Q. Su, Zhejiang University, Zhejiang, China

8.7-6: Assessment of Oxygen Transfer in Hyperbaric Dual Mode Liquid-Type Oxygenator for ECMO

T. Tsuji, K. Tanishita*, M. Takahashi**, and T. Togawa, Tokyo Med. & Dental Univ., Tokyo, Japan, * Keio

University, Japan, ** Res, Inst, of Applied Engr., Hokkaido University, Japan

1540

1541

1543

1545

1546

1549

1551

1553

1555

1557

Track 9:

Session 1.

9.1-1:

9.1-2:

9.1-3:

9.1-4:

9.1-5:

9.1-6:

Biosensors

Optical Sensors

Microfabrication of an Integrated Optoelectronic PtcC02 Sensor

C.H. Morgan and P.W. Cheung, Dept. of Electrical Engineering, Center for Bioengineering, University of

Washington, Seattle, WA

IR Spectroscopic Detection of Whole Blood Cholesterol

N. Haq, A. Garton* and M.D. Fox, Dept. of Electrical & Systems Eng., institute of Material Sciences,

University of Connecticut, Storrs, CT

Development of a Near-Infrared-Raman Sensor for Medical and Surgical ApplicationsQ. Ren, S. Nie* and N.-T. Yu**, Opthalmic Biophyscics Center, Bascom Palmer Eye Inst., University of Miami,

FL, *Georgia Inst, of Tech., Atlanta, GA, **Dept. of Chem., Hongkong Univ. of Sci. and Technology, Hongkong

Monitoring of Heart- and Respiration Rates Using a Fiber Optic Sensor

H. Ugnell, L.-G. Lindberg and P.A. Oberg, Dept. of Biomedical Engr. University of Linkoping, Sweden

Venous Occlusion Plethysmography Based on Fiber Optic Sensor Using the MicrobendingPrincipleE. Stenow, H. Ronman, L.-E. Eriksson and P.A. Oberg, Dept. of Biomedical Engr., University of Linkoping,Sweden

Laser Polarimetry for Measurement of Drugs in the Aqueous Humor

S.P. Kozaitis, F.M. Ham, G.M. Cohen* and G. Han, Dept. of Elect. & Computer Engineering, Florida Inst, of

Technology, *Dept. of Biological Sciences, Florida Inst, ofTech., Melbourne, FL

Session 2. Biochemical and Electrochemical Sensors

9.2-1:

9.2-2:

Glucose Sensing Using AC Oscillographic ChronopotentiometryW. Xu, S.J. Yao and S.K. Wolfson Jr., Dept. of Neurological Surgery and Surgery, Univ. of Pittsburgh &Surgical Res. Lab., Monteflore University, Pittsburgh, PA

Glucose Sensing Using Infrared Absorption Spectroscopy and a Hybrid Artifical Neural Network

F.M. Ham, G.M. Cohen* and B. Cho, Dept. of Electrical & Computer Eng *Dept. of Biological Sciences, Florida

Institute of Technology, Melbourne, FL

1560

1562

1564

1566

1568

1570

1572

1574

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Table of Contents EMBS 1991

9.2-3: Highly Sensitive Measurement of Biochemical Substances Based on ATR/ FT-IR Technique 1577

Y. Miyahara, T. Buhrer, T. Fuji! and Y. Watanabe, Central Research Lab., Hitachi Ltd., Tokyo, Japan

9.2-4: Performance of the Lithium Electrode for Direct Whole Blood Determination 1579

B. Gougel, Y. Garcera, Y. Gourmelin and A. Truchaud, Lab. de Biochimie, Centre Hospitaller General de

Meaux, Meaux, France

9.2-5: Design of A Conductimetric Microsensor Based on pH-Sensitive Polymer Hydrogels 1581

N.F. Sheppard, Jr., S, Salehi-Had and R.C. Tucker, Dept. of Biomedical Engineering, The Johns HopkinsUniversity, Baltimore, MD

9.2-6: The Development of a New Miniature Thin Film Dissolved Oxygen and Ionic Conductivity 1583

Sensor and Measurement SystemG. Li, Y. Q. Chen, X. P. Wu, and W. X. Lu, Dept. of Scientific Instrumentation, Zhejiang University, *Fudan

University, China

Session 3. Biomedical Electrodes and Associated Measurements

9.3-1: Optimum Preparation and Storage of Ag/Cl and Pt Black Microelectrodes for Transmural 1585

Cardiac Recording ApplicationsT.W. Tsuei, R.H. Henderson and H.Z. Massoud, Dept. of Electrical Engineering, Duke University, Durham, NC

9.3-2: Active Electrodes for Electrical Impedance Tomography: The Limitation of Active Stray 1587

Capacitance Compensation

B. Rigaud, P.M. Record*, J. Anah and J.P. Morucci, Unite de Recherche et Transfert Indust. en Tech.

Biomedicale, INSERM, Toulose, France, *Dept. of Biomedical Engr., Univ. of Keele, U.K.

9.3-3: Development of Integrated Electrodes to Measure Visually Evoked Potential 1589

P.A. Patel, N. Barsalou* and H. Kothari, University of Texas at San Antonio, *Brooks Air Force Base, San

Antonio, TX

9.3-4: Interdigitated Gate Electrode Field-Effect Transistor (IGEFET) Sensor for Detecting Nitrogen 1591

Dioxide (N02) and Disopropyl Methylphosphonate (DIMP)

E.S. Kolesar, Jr. and J.M. Wiseman, Airforce Institute of Technology, Wright-Patterson AFB, OH

9.3-5: Continuous Measurement of Cerebral Water Content by Time Domain Reflectometry 1593

G.G. Kramer, E. Shwedyk and E.R. Cardoso*, Dept. of Electrical and Computer Engr., University of Manitoba,

Cerebral Hydrodynamics Lab. Health Sciences Clinical Research Centre, Winnipeg, Canada

9.3-6: Autonulling MOS Bridge for Sensor Applications 1595

P.P. Bey Jr., M.D. Levine, D.J. Yonce and T.L. Fare*, Geo-Centers, Inc., Ft. Washington, MD, *Naval Research

Lab. Center for Bio/Molecular Science & Engr., Washington, DC

Session 4. Miscellaneous Sensors and Sensor Phenomena

9.4-1: Ultrasonic Respiration Analysis

Ch. Buess, R. Burger and W. Guggenbuhl, Dept. of Electronics, Swiss Federal Institute of Technology, Zurich,

Switzerland

9.4-2: Multisensor Catheter for Invasive Measurement of Blood Parameters

Y. Manoli, J. Eichholz, M. Kandler, N. Kordas, A. Langerbein, W. Mokwa, M. Fahnle* and F.F. Lelbscher*,

Fraunhofer-Inst. of Microelectronic Cir. & Sys., Duisburg,* Inst, of Med, Tech., Munster, Germany

9.4-3: A Thin-Film Variable Capacitance Shear Force Sensor for Medical and Robotics Applications

K.-I. Akasofu and M.R. Neuman, Dept, of Biomedical Engr. and Reproductive Biology, Case Western Reserve

University, Cleveland, OH

9.4-4: Characterization of New Radiation Detector for Bio-ApplicationI. Yu, W.V. Subbarao and M.L. Heimer, Dept. of Electrical and Computer Engineering, Florida International

University, Miami, FL

9.4-5: Self-Labeling of Bacteria with a Luminescent PolymerJ.L. Kiel, J.E. Parker, J.L. Alls and R.A. Weber, Radiofrequency Radiation Branch, Directed Energy Div., USAF

Armstrong Laboratory, Brooks AFB, TX

9.4-6: Modification of Polysulfone for Membrane Bound Enzyme Sensors

U. Bhowmick, G. Venkidachalam and S. Basu, Dept. of Chemistry, and School of Biomedical Engr., Indian

Institute of Technology, Bombay, India

1597

1599

1601

1603

1605

1607

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Table of Contents EMBS 1991

Session 5. Oximetry

9.5-1: Inaccuracy of Pulse Oximeter Readings due to Carboxyhemoglobin 1608

J.C.S. Lee, P.W. Cheung, R.B. Schoene*, M.A. Kenny** and S Goldberg*, Ctr. for Bioengin., Washington

Technology Ctr.,*Pulmonary & Exercise Lab., Harborview Med. Ctr.,**Endocrinc & Stat Lab., Univ. of WA

Hosp.

9.5-2: A Noninvasive Reflectance Pulse Oximeter Sensor 1610

S. Takatani, C. Davies*. G.P. Noon, Y. Nose and M.E. DeBakey, Dept. of Surgery, Baylor Coll. of Medicine,

Houston, TX, *Dept. of Artif. Organs, Cleveland Clinic Foundation, Cleveland, OH

9.5-3: Near Infrared Monitoring of Oxygenation During Acute Brain Ischemia and Hypoxia 1612

T. Wang, J.K.-J. Li and D. Amory*, Dept. of Biomedical Engin., Rutgers Univ., Piscataway, NJ, *Dept. of

Anesthesia, Robert Wood Johnson Medical School, New Brunswick, NJ

9.5-4: Automatic Feedback Control of Oxygen Therapy Using Pulse Oximetry 1614

N. Azhar, and U. Karim*, Dept. of Biomedical Engr., Shaikh Zayed Fed. Posgraduate Medical Inst., * Dept. of

Elect. Engr., Univ. of Engr. and Technology, Lahore, Pakistan

9.5-5: A Device for Ambulatory Heart Rate, Oxygen Saturation and Snoring Recording 1616

T. Penzel, W. Althaus, K. Meinzer*, J.H. Peter and P. von Wichert, Med. Poliklinik,, *Central Lab. for

Electronic Development, Philipps-University Marburg, Germany

9.5-6: An Improved Ambulatory Oxygen-Uptake Monitor 1618

T. Tamura, T. Higuchi* and T. Togawa**, Dept. of Electrical & Electr. Eng., Yamaguchi Univ., *Dept. of

Mechancial Eng., Waseda University, **Inst for Medical & Dental Eng., Tokyo Med. & Dent. Univ., Japan

Session 6. Sensor Design and Acquisition/Monitoring Techniques

9.6-1: A System for Testing a Multielement Tactile Sensor Array 1620

G. Magenes, G. Canepa* and F. Germagnolt, Dip. di Informatica e Sistemistica, University of Pavia, Italy,Centro Piagglo, Univ. of Pisa, Italy

9.6-2: An Inductive Sensor for Recording of Fetal Movements and Sounds 1622

H.G. Goovaerls, H.P. van Geijn* and O. Rompelman, Dept. of Medical Physics, *Dept. of Obstetrics &

Gynecolgy, Free University, Amsterdam, The Netherlands

9.6-3: Thin-Film Planar Optical Waveguide Sensor for Biochemical Assay 1624

S. Kang, K. Sasaki* and H. Minamitani, Dept, of Biomedical Engr,, *Dept. of Material Science, Keio

University, Yokohama, Japan

9.6-4: Continous Doppler Sonography: The Technical Fundamentals for Clinical Long Term 1626

MonitoringB. Bresser, R.M. Schmitt, B. Grohs, H.-J. Welsch, H. Rabe* and G. Jorch*, Fraunhofer Inst, for Biomed.

Engr., Dept. of Ultrasound, St. Ingbert, *Dept. of Pediatrics, Univ. Hosp. of Munster, Germany

9.6-5: Intra and Inter Electrode Charge Distributions and their Effects on Threshold Excitation of 1628

Human Peripheral Motor Nerves

G. Kantor, G. Alon* and H.S. Ho, Center for Devices and Radiological Health, FDA, Rockville, MD, * Dept. or

Physical Therapy, Univ. of Maryland Medical School, Baltimore, MD

9.6-6: Biaxial Esophagus Microphone Recording of Lung Sound 1631

J. Vanderschoot, H.J.W. Schreur*, Medical Informatics, Univ. of Leiden, *Dept. of Pulmonology, Univ. Hospitalof Leiden, Leiden, The Netherlands

Track 14: Critical Care MonitoringSession 1. Developments in Critical Care Monitoring

14.1-1: Physiological Monitoring Evaluation: Can Everyone Agree? 1633

D.S. Bell and I.S. Tackel, Dept. of Biomedical Instrumentation, Thomas Jefferson University Hospital,Philadelphia, PA

14.1-2: A Computerized Procedure for the Analysis of Poligraphic Signals in Intensive Care Units 1635

M.G. Signorini, P. Prandini, B. Allaria*, M. Dei Poll* and S, Ccrutti**, Dept. or Biomed. Engr., Polytech.Univ., Milano, *ICU, S. Corona Hosp.,**Dept. oflnrorm. & Sys. Sci., Univ. "La Sapienza", Italy

14.1-3: Computers in ICU Monotoring: An Intelligent Semantic-Based Method 1637

V. Moret-Bonillo, A. Alonso-Betanzos, E.J, Truemper*, and J.R. Searle**, Dept. Computacion, Univ. La

Coruna, La Coruna, Spain,*Dept. Pediatrics, and **

Dept. Biomed Eng. Res, Med. Coll. of Georgia, Augusta,GA

14.1-4: Energy Measurements in ICU Patients 1639

M.S. Kemper, and A. Wald, Dept. of Anesthesiology, Columbia University, New York, NY

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14.1-5: Studies of Apnea Monitor Radiofrequency Electromagnetic Interference

P.S. Ruggera and E.R. O'Bryan, Center for Devices and Radiological Health, Food and Drug Administration,

Rockville, MD

14.1-6: Normalization of the Blood Volume Pulse for Physiological MonitoringM.L. Heimer, J.A. Puig and W.V. Subbarao, Dept. of Electrical & Computer Engineering, Florida International

University, Miami, FL

Session 2. Monitors and Instrumentation in Critical Care

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14.2-1:

14.2-2:

14.2-3:

14.2-4:

14.2-5:

14.2-6:

A New Approach to Bedside Estimation of Pulmonary Capillary Pressure Using Arterial

Occlusion Transient SignalsJ. Vidal, F. Terretaz, J.M. Vesin, M. Karrakchou, F. Felhl*, C. Perret* and M. Kunt, Lab. de Traitement des

Signaux, Ecole Polytech. Fed., Lausanne, *Inst. Physiopathologie, Switzerland

Estimate of Pulsatile Cerebral Blood Volume Change Derived from the Intracranial Pressure

SignalM.L. Daley, and J.T. Robertson*, Dept. of Electrical Engr., Memphis State Univ., Memphis, TN, * Dept.

Neurosurgery, Univ. Tenn.-Memphis, Memphis, TN

On-Line Measurements of Blood Water Concentration in the Extracorporeal Circulation of

Hemodialysis Patients

D, Schneditz, A.M. Kaufman and N.W. Levin, Beth Israel Medical Center, New York, NY

Development of Automatic Monitoring System for the Indirect Intracranial Pressure

H. Shimazu, H. Ito, T. Hashimoto*, M. Gondoh**, T. Tamai**, S. Nakamura*** and I. Ohtaka***, Dept. of

Physiol., Kyorin Univ., *Dept of Neurosurgery, Tokyo Jikei Univ., **Japan MDM, Ltd., ***ME System, Japan

Micro-Controller Based Drip Monitor

N. V. Narayan and S. B. Pharkute, Dept. of Instrumentation, College ot Engineering, Pune, India

Critical Care Monitoring in the Year 2000

G. Pelikan, W. Morse, SpaceLabs, Inc., Redmond, WA

Session 3. Anesthesia Technology

14.3-1:

14.3-2:

14.3-3:

14.3-4:

14.3-5:

14.3-6:

Track 18:

Session 1

18.1-1:

18.1-2:

18.1-3:

Decision Support in Patient Monitoring by Interactive Information System IncludingKnowledge-Based ComponentsG. Rau, T. Schecke, H. Kasmacher* and G. Kallf*. Helmholtz-Instltute for Biomedical Engin., *Clinic of

Anesthesiology, Aachen Univ, of Technology, Germany

Neural Network Analysis of Physiologic WaveformsJ.M. Goldman and B.H. Dietrich, Dept. of Anesthesiology, University of Colorado School of Medicine, Denver,

CO

Automatic Data Collection with Comandas-An Automated Anesthesia Record Keeping SystemC.B. DeVos, M.D. Abel, J.P. Abenstein and T.N. Spackman, Information Services and Dept. ofAnesthesiology,Mayo Clinic, Rochester, MN

Continuous Cardiac Output Determination: A Byproduct of Closed Circuit Anesthesia

A. Sharma, P.J, Robbiano, R.L. Griffith and R.J. Roy, Dept. of Biomed. Eng., Rensselaer Polytechnic Inst.,

Troy, NY, and Dept. of Anesthesiology, Albany Medical College, Albany, NY

Modelling Human Thermal Balance and Thermoregulatory Responses During Epidural

Anesthesia

J.M. Hynson, E.H. Wissler and D.I. Sessler, Dept. ofAnesthesia, University of California San Francisco, CA

A Study of Multi-Sensor Flow Measurements of Unknown Gas CompositionsJ.D. Pfeffer, W.J. Tompkins, D. Bathe* and R. Tham*, Dept. of Elect. & Computer Engin., Univ. ofWisconsin-

Madison, Madison, WI, * Ohmeda, Madison, WI

Instrumentation

Instrumentation for Pacing and Electrocardiography

Programmed Cardiac Pacing Using a Microcomputer as an External Control Device

P.A. Guse, K.D. Bollacker, L.A. Webb and J.S. Fontaine*. Dept. ofMedicine & Engineering, Duke University,

Durham, NC, *Allied-Signal Aerospace Co., Ft. Lauderdale, FL

A PC-Based Pacing System for Collection of Intracardiac Electrograms

C. Housworth, D. Cook and E. Schroeppel, Intermedics, Inc. AngletonTX

Analog to Digital Conversion Techniques in Implantable Devices

R.A. Walters and C.E. Harrigal, Cook Pacemaker Corporation

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18.1-5:

18.1-6:

Session

18.2-1:

18.1-4: Development of Progammable Microelectronic System-Based Cardiotachymeters

S. Soegijoko, S. Iskandar*, W. Rosiawan and M. Widardjo*, Inter Univ. Centre on Microelectronics, * Dept. of

Electrical Engr., Inst. Teknologi Bandung, Indonesia

Intermittent Recording of Continuous ECG

X.G. Yan and W.X. Lu, Institute of Biomedical Engr., Zhejiang University, Hangzhou, China

Directional Depolarization Sensors of Body Surface ECG

L. Rasqulnha, M. Kaufer and P. Tarjan, Dept. of Biomedical Engr., University of Miami, Coral Gables, FL

2. Clinical and Diagnostic Instrumentation

A Nuclear Stethoscope Concept with Compact Radiation Detector

J.J. Nainaparampil, W.V. Subbarao and K. Yen, Dept. of Electrical and Computer Engineering, Florida

International University, Miami, FL

18.2-2: Opto-Electronic Measurement of Human Skin Characteristics During Cell-Mediated Immune

Response

S.E. McCormack and J.C. Belina, School of Electrical Engineering, Cornell University, Ithaca, NY

18.2-3: The Variability of Applied Finger Pressure During Perception Threshold Testing of Carpal

Tunnel SyndromeG.L, Beauregard and J.R. LaCourse. Dept. of Electrical and Computer Engineering, University of New

Hampshire, Durham, NH

18.2-4: Pressure Field of Electrohydraulic Shock Wave Generators Using Electrolyte in the

Interelectrode Space

D. Cathignol, J.L. Mestas, F. Gomez and P. Lenz, INSERM, Lyon, France

18.2-5: Multimodal Lithotripsy in UrologyA. Wolf, A. Frankenschmidt, W. Schultze-Seemann, U. Wetterauer, and H. Sommerkamp, Dept. of Urology,

University Hospital, Freiburg, Germany

18.2-6: Computer-Optimized Neurological Stimulation

K.R. Fowler and R.B. North*, Applied Physics Laboratory, *Dept. of Neurosurgery, Johns Hopkins University,

Baltimore, MD

Session 3. Eye-Movement Measurements

18.3-1: Measuring Eye Movements Using the Shape of the PupilG.A. Myers, B.T. Wiemann and S.G. Carlson, Dept. of Biomedical Engr. and Electrical Engr., University of

Iowa, Iowa City, Iowa

18.3-2: An Electromagnetic Eye Movement Monitor with One Arc Second Resolution

R. Remmcl, Biomedical Engr. Dept., Boston University, Boston, MA

18.3-3: An Apparatus for Measuring Eye and Head Movements Using CCD Image Sensor and 3 Space

M. Takahashi, M. Kato, K. Mitobe, T. Izumi, T. Ifukube, J.-I. Matsushima* and K.-I. Tanaka**, Res. Inst, of

Applied Elect., *Sch. of Med., Hokkaido Univ.,**Sci. Res. Lab., Nissan Motor, Co, Japan

18.3-4: Automatic Extraction of Eye Features From Facial Images

R. Sudhakar, H. Zhuang and X. Xie, Electrical Engr., Florida Atlantic University, Boca Raton, FL

18.3-5: Muscle Dynamics During Monkey Saccadic Eye Movements and Simulated Saccadic Eye

Movements

K.D. Pfann, J.M. Miller* and E.L. Keller**, Univ. of California San Francisco/Berkeley Grad. Group in

Bioengr.,* Smith-Kettlewell Eye Res. Inst., Dept. of Elect. Engin.,** Univ. or California, Berkely, CA

18.3-6: Eye Position Sensor Used to Command a Blissymbolic Communicator

J. Tichon*,**, J. M. Toulotte*, H. De Rop**, G. Trehou*, Y. Carnol**, and P. Lardinois, * Univ. Sci et Tech.

de Lille Flanders-Artois, France,** Inst. Supcrleur Ind. de Bruxelles, Belgium

Session 4. Instrumentation for Myography

18.4-1: Evaluation of Intestinal EMG for the Assessment of Bowel ViabilityG.A. Cazi, J.L. Semrnlow, P.J, Orland* and R.E. Brolin*, Dept. of Biomedical Engr., Rutgers University,

*Dept. of Surgery, UMDNJ-RWMS, Piscataway, NJ

18.4-2: Design Optimization of a Transducer for MagnetomyographyN.P. Nantel and L.D. Pengelly, Dept. of Computer and Electrical Engineering, McMaster Univ. Medical Centre,

On, Canada

18.4-3: A Low-Power Portable Telemetry System for Eight Channel EMG Measurements

M. Steyaert, S. Gogaert, T. Van Nuland, and W. Sansen, K.U. Leuven ESAT-MICAS, Heverlee, Belgium

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18.4-4: Clinical Applications of Acoustic MyographyD.T. Barry and N.M. Cole, Dept. of Physical Medicine and Rehabilitation and Bioengineering Program,University of Michigan, Ann Arbor, MI

18.4-5: Acoustic Myography Frequencies Track the Rise of Skeletal Muscle Tetanic TensionN.M. Cole and D.T. Barry, Dept. of Physical Medicine & Rehabilitation, University of Michigan, Ann Arbor, MI

18.4-6: Action Potential Stimulation and Recording with a Portable MicrocomputerD.M. Craig, J.W. O'Brien, CM. Purut and P.K. Smith, Dept. of Surgery, Duke University Medical Center,Durham, NC

Session 5. Instrumentation for Biopotential and Impedance Measurement

18.5-1: Instrumentation for Study of Bioelectricity by Lorentz Force MagnetometryB.C. Towe, Bioengineering Program, Arizona State University, Tempe, AZ

18.5-2: Influence of Isolation on Interference in Bioelectric RecordingsC.A. Grimbergen, A.C.M. van Rijn and A. Peper, Dept. of Medical Physics and Informatics, University orAmsterdam, Amsterdam, The Netherlands

18.5-3: Analysis of a Ground Isolated Monitoring System to Common-Mode InterferenceA. Pittel, Cardiac Assist, Boston Scientific Corporation, Mansfield, MA

18.5-4: Multichannel Acquisition of Bioelectric Signals Using the Flying Capacitor TechniqueJ.f. Saiz, J.M. Ferrero Jr., J.M. Ferrero, J.L. Martinez, Dept. de Ingemeria Electronica, Universidad Polltecnicade Valencia, Spain

18.5-5: Electrical Impedance in the Lower Limbs of Patients with Duchenne Muscular DystrophyM. Noshiro, T. Morimoto*. H. Nagao* and H. Matsuda*, Div. of Elect. Engr., Tokyo Medical & DentistryUniversity, Tokyo, *Dept. of Pediatrics, Ehime Univ. School of Medicine, Japan

18.5-6: Electrode-Electrolyte Interface Impedance: The Limit Current of LinearityE.T. McAdams and J. Jossinet*, The Northern Ireland Bio-Engineering Ctr., Univ of Ulster, N. Ireland,*INSERM, Lyon, France

Session 6. Thermal and Respiratory Instrumentation

18.6-1: Design and Testing a Versatile Portable Data Acquisition System to Monitor TemperatureCircadian RhythmsM.L. Riccio, J.C. Belina, D.W. McBride Jr* and H.S. Porte**, School of Elect. Engr., *Dept. of Neurobiology &Behavior, **Dept. of Psychology, Cornell University, Ithaca, NY

18.6-2: Assessment of Deep Temperature During Bicycle ErgometryT.J. Malkinson, K.E. Cooper and W.L. Veale, Faculty of Medicine, Univ. of Calgary, Calgary, Canada

18.6-3: Non-Contact Emissivity Measurement for Radiation ThermometryT. Togawa and H. Saito, Inst, for Medical and Dental Engr., Tokyo Medical and Dental University, Tokyo,Japan

18.6-4: A Compact System for Measurement of Respiratory MechanicsL. Davis and C. Druzgalski, Dept. of Electrical Engr., California State University, Long Beach, CA

18.6-5: Automatic Control of an Artificial RespiratorF.T. Tehrani, Dept. of Electrical Engineering, California State University, Fullerton, CA

18.6-6: Ventilation Control: From High-Tech to High-Tech Low Cost

B. Rybak, Physiology, Sorbonne Paris III, Paris, France

1713

1715

1717

1719

1720

1722

1724

1726

1728

1730

1732

1734

1736

1738

1740

Track 19: Lasers and ElectroopticsSession 1. New Lasers and Applications

19.1-1: New Solid State Lasers for Medical ApplicationsM. Bass, Center for Research in Electro Optics and Lasers, Univ. of Central Florida, Orlando, FL

19.1-2: Laser Assisted Wound Closure

D.K. Dew and C.C. Darrow, II, Laser Surgery Software, Inc., Winter Park, FL

19.1-3: Electro-Hydro-Thermosation Versus C02 Laser Surger in Endolaryngeal Surgery: An

Experimental Study

H.E. Eckel, K. Dollinger*, H.-D. Reldenbach* and M, Jungehulslng, ENT Dept., Univ. ot Cologne, *Section

Medical Technique, Fachhochschule Koln, Koln, Germany

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Table of Contents EMBS 1991

Session 2. Optical Diagnostics

19.2-1: Pattern Recognition Algorthms for Tissue Diagnosis by Near-Infrared FT-Raman Spectroscopy

S. Nie, Y. Li*. D.C.B. Redd**, and N.-T. Yu***, Sch. of Chemistry & Biochemistry, Georgia Inst. otTech.,

Dept. or Elect. Engr., Wester Mich. Univ.,**Depl. otRadiology, Emory Univ., ** Dept. ot Chemistry, Hong

Kong Univ. of Sci. and Technology

19.2-2: Neurons Volumetric Visualization Through Optical Laser Scanning Microscopy

F. Beltrame, F. D'Anna*, A.T. Franzi* and G. Marcenaro, DIST, *Istituto di Anatomia Umana Normale,

Universita degli Studl di Genova, Italy

19.2-3: X-Ray Photothermal Dosimetry with Optical Fibers

F. Barone, U. Bernini, M. Conti, A. Del Guerra, L. Di Flore, P. Maddalena, L. Milano, G. Russo and P. Russo,

Dip. di Scienze Fisiche, Univ. di Napoli Federico II and INFN, Napoli, Italy

19.2-4: Estimation of Sampling Depth in Laser Doppler Flowmetry Based on a Monte Carlo Model

A. Jakobsson and G.E. Nilsson, Dept. of Biomedical Engr., Linkoping University, Sweden

19.2-5: A Demonstration of Reflectance from Muscle Underneath Dermis or Fat in a Layered Ex Vivo

Biological Tissue Model

L.E. Ostrander and W. Cul, Biomedical Engineering Dept., Rensselaer Polytechnic Institute, Troy, NY

19.2-6: A Laser Scanner System for Investigating Non-Invasive Matching Strategies in Computer-

Assisted Orthopaedic SurgeryS. Martelli, M. Fadda, P. Darto, M. Marcacci, G.P. Marcenaro and A. Visani, Lab. di Biomeccanica, Istiluti

Ortopedici Rlzzoli, Bologna, Italy

1747

1749

1751

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1757

Session 3. Mini-Symposium Laser Medicine and Electrocautery

19.3MS-1: Analysis of Fumes During PMMA Preparations with a C02-Laser

R. Inglis, A. Hermann!, J, Windolf and A. Pannike, Dept. of Traumatology, J.W. Goethe University Hospital,Frankfurt, Germany

19.3MS-2: New Development for Temperature Controlled Bipolar Coagulation in Laparoscopic SurgeryK. Buhler, U. Winkler, K. Kato andA.E. Schindler, Dept. ot Gynaecology, University of Essen, Germany

19.3MS-3: The Endoscopically Controlled Laser Lithotripsy of Salivary Stones

C. Scholz*, P. Gundlach, J. Hopr, N, Leege. J, Tschcpe*, T. Ertl*, H. Scherer and G. Muller*, ENT Dept., Freie

Universltat Berlin, *Laser-Medlzin-Zentrum, Berlin, Germany

19.3MS-4: The Elektrotom "BiCut-System" for Bipolar Cutting and Bipolar Haemostasis

Th. Krober and E. Roos, Berchtold GmbH & Co., Medical Electronic Equipment, Tuttllngen, Germany

19.3MS-5: Laser in Therapy of Urological Stones and Tumors

A. Wolf, O. Hakenberg, U. Koppermann, U. Wetterauer and H. Sommerkamp, Dept. of Urology, University

Hospital, Freiburg, Germany

19.3MS-6: Electrohydrothermic SurgeryH.-D. Reldenbach, Fachhochschule Koln, Forschungsbereich Medizintechnik/HLT, Koln, Germany

Session 4. Laser Angioplasty and Other Diagnostics

19.4-1: Laser Hot Balloon Catheter for Stenotic Coronary Disease

T. Aral, M. Sakurada*. A. Miyamoto*, K. Mizuno*, K. Arakawa*, T. Shibuya*, A. Kurita*, H, Nakamura*. M.

Kikuchi, A. Utsumi**, Y. Akai***, and K. Takeuchi*** *, Dept. or Med. Engr.,*Dept. of 1st Int. Medicine, Nat.

Def. Med. Col., ** Mitsubishi Cabel,*** Hamamatsu Photonics, **** Fukuda Denshi, Japan

19.4-2:, Fluorescence Quenching of Arterial Plaque Stained with b-Carotene

B. Ye and G.S. Abela, Institute for Prevention of Cardiovascular Disease, New England Deaconess Hospital,Harvard Medical School, Boston, MA

19.4-3: Near-Infrared Fourier Transformed-Raman Spectroscopy for Laser AngioplastyS. Nei. Q. Ren*, D.C.B. Redd**, S.B. King** and N.-T. Yu***, Georgia Inst, of Tech., GA, *Bascom Palmer EyeInst., FL, **Emory Univ., GA, ***Hongkong Univ. of Science and Technology, Hongkong

19.4-4: Basic Study on Effects of Argon-Laser Irradiation for the Blood-Brain Barrier

Y. Morimoto, T. Aral*, M. Kikuchi*, S. Nakajima and H. Nakamura, Dept. 1st Internal Medicine and * Dept. or

Medical Engineering, Nat. Defense Medical College, Sattama, Japan

19.4-5: Application of Combined C02 Nd-Yag Laser with Scanning Devices for Gerontological PatientsO.S. Panova and A.G. Sutiaguin, USSR Academy of Sciences Central Clinical Hospital, Centre or

Cosmetological Correction, Moscow, USSR

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19.4-6: Absorption Coefficient of Animal Tissues in the Range 250—700 nm via Photoacoustics 1778

U. Bernini, M. Contl, A. Del Guerra and P. Russo, Dip. dl Scienze Fisiche, Univ. di Napoli Federico II and

INFN, Napoli, Italy

Track 23: Molecular Electronics

Session 1. Mini-Symposium Molecular Electronics

23.1MS-1: Neuromolecular Computing: An Overview

M. Conrad, Dept. of Computer Science, Wayne State Univ., Detroit, MI

23.1MS-2: Langmuir-Blodgett Films of Molecular Conductors

R.M. Leblanc, Centre de Recherche en Photobiophysique, Univ. du Quebec a Trois-Rivieres, Trois-Rlvleres,

Que., Canada

23.1MS-3: Application of Conducting Polymers in Redox Devices and Intelligent Materials SystemsR.H, Baughman, Allied-Signal Inc., Morrlstown, NJ

23.1MS-4: A Rotary Biomotor: Structure, Characteristics and RegulationN. Kami-Ike, S. Kudo, Y. Magariyama, S.-I. Aizawa*, and H. Hotani*, Molecular Dynamic Assembly Project,ERATO, JRDC, Kyoto, Japan, *Dept. of Biosciences, Teikyo University, Toyosatodai, Japan

23.1MS-5: Molecular Electronics: From Nonlinear Optics to Scanning Tunneling MicroscopyR.S. Potember, The Applied Physics Laboratory, The Johns Hopkins University, Laurel, MD

23.1MS-6: Design and Fabrication of Biomolecular Electronic Devices and Neuro Devices

N, Aizawa, Dept. of Bioengineering, Tokyo Institute ofTechnology, Yokohama, Japan

Session 2. Molecular Electronics

23.2-1: Development of Biosensors on the Basis of Langmuir-Blodgett Films

B. Ebert, S.-M. Chang*, E. Tamiya*, and I. Karube* Physikalisch-Technische Bundesanstalt, Berlin, Germany,RCAST, Univ. of Tokyo, Komaba, Meguro-ku, Tokyo, Japan

23.2-2: Optical Second Harmonic Generation in Langmuir-Blodgett Films of N-docosyl-2-methyl-4-nitroaniline

V.A. Howarth, N. Asai, N. Kishii and I. Fujiwara, Sony Corporation Research Centre, Yokohama, Japan

23.2-3: Computer-Aided Design in Study of Molecular Devices

Y. Wei, Z, Ai, Z. Gu and J. Liu, Lab. of Molecular and Biomolecular Electronics, Southeast University, Nanjing,China

23.2-4: Molecular Electronic Properties of Flavin-Porphyrin Hetero LB Films

S, Ueyama, O. Wada* and S. Isoda, Central Research Lab,, *Material & Electronic Lab., Mitsubishi Electric

Corporation, Hyogo, Japan

23.2-5: On the Interconnection of Molecular Processing Devices

K. Akingbehin, Electrical and Computer Engr. Dept,, University of Michigan, Dearborn, MI

Track 31: Rehabilitation EngineeringSession 1. Rehabilitation Engineering III: PES/FNS for Persons with Disabilities

31.1-1: An Eight-Channel Computer Controlled Stimulator for Functional Electrical Stimulation 1803

T. Ellinger, M, Wild, H. Gerber, E. Stussi, and S. Hacisalihzade*, Swiss Fed. Inst, of Technolgy (ETH), Zurich,

Switzerland, * Landis & Gyr AG, Zug, Switzerland

31.1-2: Optimization of the Relationship between Pulse Width, Pulse Frequency and Sensation 1805

Thresholds for Vibrotactile Information Transfer

CA. Perez and H.R. Weed*, Dept. of Ingenieria Electrica, Univ. of Chile, Santiago, Chile, *Dept. of Electrical

Engineering, Ohio State Univ., Columbus, OH

31.1-3: Instrumented Assessment of FNS Hand Control During Specific Manipulation Tasks 1807

J.C. Burelbach and P.E. Crago, Dept. or Biomedical Engineering, Case Western Reserve University, Cleveland,

OH

31.1-4: The Current Requirements and the Pain Response for Various Sizes of Surface Stimulation 1809

Electrodes

R.P. Patterson and J.S, Lockwood, Dept. of Physical Medicine and Rehabilitation, University or Minnesota,

Minneapolis, MN

31.1-5: Postural Control During One-Arm Support Standing: EMG Characterization 1811

M. Moynahan, R.J. Triolo and R.R. Betz, Functional Neuromuscular Stimulation Lab., Shriners Hospital for

Crippled Children, Philadelphia, PA

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31.1-6: Pilot Study: Application of Intramuscular Stimulation to Upper Extremity Musculature of a 1814

Child with Spastic Quadriparesis, Cerebral PalsyB.T. Smith, M.J. Mulcahey, R.J. Triolo and R.R. Betz, Functional Neuromuscular Stimulation Lab., Shriners

Hospital for Crippled Children, Philadelphia, PA

Session 2. Rehabilitation Engineering I: Wheeled Mobility and Seating

31.2-1: SMARTWheels: A Device for Studying Wheelchair Propulsion Dynamics 1817

K.T. Watanabe, R.A. Cooper and J.F. Ster III, Human Engineering Lab., Biomedical Engineering Program,California State University, Sacramento, CA

31.2-2: Human Exoskeleton for Handicapped on-Board Mobility II 1819

A. Mortersen, H. Weed and P. Sikora*, Dept. of Electrical Engin., The Ohio State University, Columbus, OH,

Consultant, Cleveland, OH

31.2-3: Using the Eye Wink Control Interface to Control a Powered Wheelchair 1821

E.E. Crlsman*, A. Loomts**, R. Shaw and Z. Laszewski, Dept. of Vet. Aff, Med. Ctr., Providence, RI, *Div. of

Engineering, **Insl. for Res. in Information and Scholarship, Brown Univ., Providence, RI

31.2-4: Vertical Lift Chair for Limb Girdle Weakness 1823

J.E. Letcchipia, J.K. Lipton*, and R.E. Bcnner**, Good Shepherd Rehab. Hospital, * Assist. Technology, Inc.,** Dept. of Mechanical Engr., Lehigh Univ., Allentown, PA

31.2-5: Establishing of Access Standards for the Mexican Institute of Social Security 1825

R.E. Mayagoitta and M. Percz-Bravo, Dept. of Mechanical and Electrical Engineering, Univ. Ibcroamerlcana,

Mexico

Session 3. Rehabilitation Engineering II: Computer Access and Augmentative Communication

31.3-1: Efficient Mappings of Continuous Motion into Speech 1827

A. Huryn, R. Williams and L. Ferber, Dept. or Electrical Engineering University of Virginia, Charlottesville, VA

31.3-2: A Data Collection and Signalling Device for the Verbally Impaired 1829

C. Chan-Nui, M.Q. Howard, R.L. Nansel*, J.M. Ellcr* and Y. Kim, Dept of Electrical Engr., Univ. or

Washington, *Dept. or Social & Health Services, Fircrest School, Seattle, WA

31.3-3: Conductive Polymer Sensors as Input Interfaces for Handicapped Children 1831

S. Saha, P.A. Williams and E.N. Roots*, Dept. of Orthopaedic Surgery LSU Medical Center, Shreveport, *Dept.or Electrical Engr., La Tech University, Ruston, LA

A Digitizing Touch-Tablet/Synthetic Speech Computer Interface 1833

J. Brabyn and W. Loughborough, The Smith-Kettlewell Eye Research Institute, San Francisco, CA

An Image Acquisition Subsystem for Tactile Vision Substitution 1835

T.S. Spisz and H.R. Weed, Dept. or Electrical Engineering, The Ohio State University, Columbus, OH

Communication and Errors in Single Switch Controlled Auto-Scanning Communication Aids 1837

L.E. French and N.P. Reddy, Biomedical Engr., University or Akron, and Edwin Shaw Hospital, Akron, OH

Rehabilitation Engineering IV: Performance Measurement and Analysis

Validation of the Wheelchair Aerobic Fitness Trainer and Test Protocol 1839

W.E. Langbein*, C.J. Robinson*, **, and CM. Reid*, * Rehabilitation R&D Center, VAH Mines, Hines, IL,**

Dept. of Neurology Loyola Univ. Strich Sell, of Medicine, Maywood, IL

31.4-2: Relationship Between Kinematic Factors and Muscle Activity During Wheelchair Propulsion 1841

Y.T. Wang, H. Deutsch, B. Hedrick* and M. Morse*, Dept. of Kinesiology and *Rehabililation Education

Center, University of Illinois, Urbana-Champaign, IL

31.4-3: Development of a Model Rehabilitation Engineering Program 1843

R, Cooper, A. Cook, and T. Grey, Dept. of Electrical and Electronic Engineering, California State University,Sacramento, CA

31.4-4: The Design and Development of Biofeedback Devices for the Rehabilitation of Oral Dysphagia 1845

S.M. Sukthankar, N.P. Reddy, E.P. Canilang, J. Casterline and L. Stephenson, University ol Akron, and Edwin

Shaw Hospital, Akron, OH

31.4-5: Biolink: A new Myoelectric Pointing Device for Interactive Computer Systems: Evaluation of 1847

the Human Performance & Integrated Realization

F. Aubin, M. Slamani*, B. Kaminska* and J.M. Robert**, Biolinka *Dept. de genie electrlquc, **Dept. de

genie tndustriel, Ecole Polytechnique de Montreal, Montreal, Canada

31.3-4:

31.3-5:

31.3-6:

Session 4

31.4-1:

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Session 5. Rehabilitation Engineering V: Orthotics and Prosthetics

31.5-1: Application of Ultrasonic Imaging Technique to Prosthetic Socket Design 1849

P. He, K. Xue*, H.A. Bismar, H. Fu* and P. Murka**, Dept. of Biomed. & Human Factors Eng., *Dept. of

Elect. Engin., Wright State Univ., Dayton, OH, **Fidellty Orthopedic, Inc., Dayton, OH

31.5-2: The Design and Development of an Orthotic Evaluation System 1851

E. Muik, R. Davis*, D. Tyburski*and J. Fezio**, Rehabilitation Eng., *Orthopaedics, **Orthotics &

Prosthetics, Newington Children's Hospital, Newington, Connecticut

31.5-3: Evaluation of a 316LVM "Woven Eye" Electrode for Direct Bladder Stimulation 1853

J. Walter.S. Cogan*, N. Nguyen*, C. Robinson, B. Dunn, P. Zaszczurynski, and J. Wheeler, Rehab. Res. &

Dev. Center, VA Mines Hospital, HinesJL, * EIC Labs, Norwood, MA

31.5-4: Progress in Penile Prosthesis 1855

A. Wolf, A. Katzenwadel, T. Kreutzig, K. Rudiger, H. Sommerkamp, Dept. of Urology, University Hospital,Freiburg, Germany

31.5-5: A Method for Numerically Rating Physical Manual Dexterity 1857

D.C. Johnson, J.R. LaCourse and D.L. Lizotte, Dept. of Electrical Engineering, University of New Hampshire,Durham, NH

31.5-6: Mexican Design of an Impotence Prosthesis Using Silicone Rubber 1859

M.A. Herreramoro J.L. Perez-Silva*. F. Ugarte-Y-Romano** and R.E. Mayagoitia, Univ. Iberoamaricana, * Univ

Nacional Autonoma de Mexico, **Hospital Angeles del Pedregal, Mexico

Session 6. Rehabilitation Engineering VI

31.6-1: The Actimeter: Analyzing Bilateral Functional Mobility 1861

S.C Koenig and J.R. LaCourse, Dept. of Electrical and Computer Engineering, University of New Hampshire,

Durham, NH

31.6-2: An Evaluation of Different Designs of Providing Powered Propulsion for Attendant Propelled 1863

Wheelchairs

E. Abel, T. Frank, G. Boath and N. Lunan, School of Biomedical Engr. University of Dundee, Dundee,

Scotland, UK

31.6-3: A New Hospital Wheelchair 1865

E. Abel and T. Frank, School of Biomedical Engr,, University of Dundee, Scotland

31.6-4: Development of a New ISO Wheelchair Two-Drum Tester 1867

R. Cooper, J. Ster III and T. Heil, Dept. of Electrical and Electronic Engineering, and Dept. of Mechanical

Engineering, California State Univ., Sacramento, CA

31.6-5: A Simple Communication Switch for Disabled 1869

A.C Wong, A. Lew, R.L. Nansel*, J.M. Eiler* and Y. Kim, Dept. of Electrical Engin., University orWashington,

*Fircrest School, Wash. State Dept. ol Social & Health Services, Seattle, WA

31.6-6: The Effects of a Lower Body Positive Pressure Suit on the Cardiovascular Capacities of Spinal 1871

Cord Injured Individuals

K.H. Pitetti, D.E. Malzahn and K.D. Campbell, Dept. of Health, Administration, Gerontology & Industrial

Engineering, The Wichita State University, Wichita, KS

Track 33: Speech, Hearing, and Vision Aids

Session 1. Speech and Hearing I

33.1-1: Resonant Pressure Transmission to the Inner Ear

R.L. Seaman and R.F. Barron, Dept. of Biomedical Engineering & Mechanical Engineering, Louisiana Tech

University, Ruston, LA

33.1-2: A Speech Analysis/Synthesis Software System for Hearing Research

Y. Joly and H.C. Lee, Dept. or Electrical Engineering, McGill Univ., Montreal, Canada

33.1-3: Speech Recognition Using Myoelectric Signals with Neural Networks

M.S. Morse, Y.N, Gopalan* and M. Wright, University or San Diego, San Diego, CA, * Auburn University,

Aurburn, AL

33.1-4: Auditory Brainstem Response Classification Using Modular Neural Networks

H. Wen and O. Ozdamar, Dept. or Biomedical Engineering, University or Miami, Coral Gables, FL

33.1-5: Two Dimensional Filtering of Auditory Evoked Potentials for Signal Enhancement

O. Ozdamar and R. Delgado, University of Miami, Dept. of Biomedleal Engineering, Coral Gables. FL

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1875

1877

1879

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33.1-6: Speech-Based Automatic Detection of Physiological Cleft Palate

H.S. Hayre and P.N. Hayre, Houston, TX

Session 2. Speech and Hearing II

33.2-1: A Dynamic Three-Dimensional Representation of the Tongue Surface Based on Ultrasound

Scans for Time-Varying Vocalizations

M. Cordaro, M. Stone*, M.H. Goldstein and M. Unser*, Sensory Commun. Lab., The Johns Hopkins Univ.,

Baltimore, MD, *National Institutes of Health, Bethesda, MD

33.2-2: Noise Reduction for Hearing Aids: Evaluation of the Adaptive Beamformer ApproachM. Kompis and N. Dillier, Dept. of ENT, Inst, for Biomedical Engin., University and Swiss Federal Institute of

Technology, Zurich, Switzerland

33.2-3: DSP-Implementation of a Multiband Loudness Correction Hearing AidT. Frohlich and N. Diller, ENT-Dept., University Hospital, Zurich, Institute for Biomedical Engineering,University & Swiss Federal Institute of Technology, Zurich, Switzerland

33.2-4: The Basis for a Round Window Electromagnetic Implantable Hearing AidJ.H. Spindel, J,T. Corwin, R.A. Ruth and P.A. Lambert, Dept. of Otolaryngology and Biomedical Engr.,

University of Virginia, Charlottesville, VA

33.2-5: Sound Synthesizer and Acoustic Measurement System for Psychoacoustic Research

A.M. Engebretson and M.P. O'Connell, Central Institute for the Dear, St. Louis, MO

33.2-6: Long Term Use of a Tactile Hearing Aid on the Identification of Vowels and Discrimination of

Consonants

E.M. O'Brien, Biomedical Engineering Dept., Mercer University, Macon, GA

Session 3. Speech and Hearing III

33.3-1: Electrotactile Information Processing SpeedA.Y.J. Szeto and D. Lin, Dept. o( Electrical & Computer Engineering, San Diego State University, San Diego,CA

33.3-2: A Solution to the Inverse Problem: A Method for Determining the Driving Currents for Focused

Stimulation

K. Rodenhiser, M. Suesscrman and F. Spelman, Dept. o( Electrical Engineering, Center for Bioengineeringand the Regional Primate Center, University of Washington, Seattle, WA

33.3-3: Digital Speech Processor for the Nucleus 22-Channel Cochlear ImplantH. Bogli and N. Diller, ENT-Dept., University Hospital, Inst, for Biomedical Engineering, University & Swiss

Federal Institute or Technology, Zurich, Switzerland

33.3-4: An Improved Sound Processor for a Multiple-Channel Cochlear ImplantH.J. McDermott, CM. McKay and A.E. Vandali, Dept. or Otolaryngology, University or Melbourne, Parkville,Australia

33.3-5: Design of a DSP-Based Extracochlear Prosthesis

T. Ifukube, Y. Hirata, T. Izumi and J. Matsushima, Research Inst, or Applied Electricty, Hokkaido University,Sapporo, Japan

33.3-6: Characterization of Surface-Measured Potentials from Implanted Cochlear Prostheses

J. Heller, N. Brehm, T. Sinopoli and J. Shallop*, Cochlear Corporation, *Denver Ear Institute, Englewood, CO

Session 4. Hearing and Vision

33.4-1: A Real-Time Evoked Potential Data Acquisition SystemF. Zhu, J. Lin and H. Zhu, Dept. or Bioengineering, Huazhong Univ. ol Science and Technology, Wuhan,China

33.4-2: Evaluation of the Dynamics of the Macular Recovery in Diabetic Subjects Through Single-Sweep VEP's AnalysisA. Bianchi, R. Magni*, L. Radice**, F. Bandello*, D. Liberati**, R. Brancato* and S. Cerutti***, IRCCS S.

RaffaeleHosp., *Univ. ofMilano, **Polytech. Univ., ***Untv. orRoma, Italy

33.4-3: Differences in Color Vision Between Racial GroupsM.L. Daley, G.A. Burghen*. D. Meyer**, and P. Malsky**, Dept. of Electrical Engr., Memphis Stale Univ.,*Pediatrics, Univ.Tenn-Memphis, Memphis, TN, ** Vitreoretinal Foundation, Memphis, TN

33.4-4: Manual and Automatic Programmable Audiometer

CA. Martinez-Baez, L.F. Borjon, and A. Noyola, Universidad Iberoamcricana, Dept. de Ingenleria Mecanica yElectrica, Paseo de la Reforma, Mexico

1883

1885

1887

1889

1891

1893

1895

1897

1899

1901

1903

1905

1907

1909

1911

1913

1915

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33.4-5: Vestibular Electric Responses to Combined Electrical and Vestibular Stimulations

J.-M. Aran, R.C. de Sauvage and J.-P. Erre, Lab. d'Audiologie Experimentale, INSERM, Bordeaux, France

Session 5. Vision

33.5-1: Sonic Electronic Guide for the Blind

S.S. Ng, Electrical Engr. Dept., National University or Singapore, Singapore

33.5-2: A Trial Development of A Map Data Base System for the Blind

N. Ohnishi, H. Minagawa* and N. Sugie*, Dept. or Electrical Engr., *Dept. or Information Engr., Nagoya

University, Nagoya-shi, Japan

33.5-3: A Design of Real-Time Head Position Monitor for Video-Based Eye Monitoring SystemH. Nakamura, H. Kobayashi, K. Taya* and S, Ishigami*, Dept. ot Elect. Engr., Saitama Inst, ot Technology,

*Dept. ot Rehabilitation, National Defense Medical College, Japan

33.5-4: Accuracy Difference Between Visually Triggered and Internally Guided Saccade-Comparison in

Skeletal and Retinal Coordinate Systems

Y. Ebisawa, T. Inagaki*, M. Ohmori*, Y. Takahashi* and H. Minamitanl* Fac. or Engr., Shizuoka University,*Fac. ot Science and Technology, Keio University, Japan

33.5-5: An Adaptive Approach to Edge Detection Based on Visual PerceptionZ. Tlanxu, Inst, ot Pattern Recognition & Artificial Intelligence, Huazhong University of Science and

Technology, Wuhan, P.R. China

33.5-6: A Versatile Digital Display Reader for the Visually HandicappedR.N. Gorgui-Naguib, Dept. ot Electrical and Electronic Engr., University ot Newcastle upon Tyne, U.K.

Track 35: Technology for the AgedSession 1. Technology for the Aged

35.1-1: Computer-Controller, Air-Modulated Mattress for the Prevention of Decubiti

D.R. Myers and J.L. Duncan, Triangle Research and Development Corporation, Research Triangle Park, NC

35.1-2: Experiences with Infusion Pumps During Home Nursing Visits

S.S. Chier, Visiting Nurse Association ot Milwaukee, West Allis, WI

35.1-3: A Fall Intervention/Mobility Aid System for Elderly and Rehabilitative Populations

D.P. Colvin, C.J. Lord, G.G. Bishop, T.W. Engel and A.L. Patra, Triangle Research and Development

Corporation, Research Triangle Park, NC

35.1-4: Falls in the Elderly: Detection and Assessment

C.J. Lord and D.P. Colvin, Triangle Research and Development Corp,, Research Triangle Park, NC

1917

1919

1921

1923

1925

1928

1930

1932

1934

1936

1938

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