hugh m. fentress · 205 zina pitcher place ann arbor, mi advisor: huda akil, ph.d. studied drug...

Hugh M. Fentress

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Hugh M. Fentress 6115 Christmas Dr.

Nolensville, TN 37135

Email: [email protected]

Email: [email protected]

Cell: (734) 355-6710 Office: (615) 963-5757

EDUCATION:

Ph.D. Vanderbilt University School of Medicine, 1999 –2005

Neuroscience Graduate Program, Nashville, TN

Major: Neuroscience

Dissertation Title: Human 5-HT2C Receptor Variants: Functional Properties and Genetic

Associations in Major Depressive Disorder

B.Sc. Tennessee State University, 1995-1999

Department of Biology, Nashville, TN

Major: Biology Minor: Chemistry

RESEARCH AND WORK EXPERIENCE:

ASSISTANT PROFESSOR, 1/16/2014-present

Department of Biological Sciences

Tennessee State University

3500 John A. Merritt Blvd.

Nashville, TN 37209

ASSISTANT PROFESSOR, 8/1/2011-12/31/2013

Department of Life and Physical Sciences – Biology

Fisk University

1000 17th Ave. N.

Nashville, TN 37208

ADJUNCT ASSISTANT PROFESSOR, 8/1/2011-present

Department of Pharmacology

Vanderbilt University School of Medicine

Nashville, TN 37232

SCIENTIST-EDUCATOR FELLOW 10/30/2008-7/31/2011

Division of Genetic Medicine


8405 Medical Research Building IV

Hugh M. Fentress

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2215 Garland Avenue

Nashville, TN

Advisor: Maureen K. Hahn, Ph.D.

Research examined the neurobehavioral consequences of norepinephrine transporter variants. I

also serve as an instructor in the brain and behavior module in the School of Medicine.

POST-DOCTORAL RESEARCH FELLOW 7/2005-10/2008

Molecular and Behavioral Neuroscience Institute (MBNI)

University of Michigan

205 Zina Pitcher Place

Ann Arbor, MI

Advisor: Huda Akil, Ph.D.

Studied drug abuse in mice overexpressing the glucocorticoid receptor.

GRADUATE STUDENT 1/2000-6/2005 Neuroscience

Graduate Program


Nashville, TN

Advisor: Elaine Sanders-Bush, Ph.D.

Dissertation Entitled: Human 5-HT2C Receptor Variants: Functional Properties and Genetic

Associations in Major Depressive Disorder.

GRADUATE STUDENT ROTATION 9/1999-12/1999

Department of Cell Biology


Nashville, TN

Advisor: Vivian Cassagrande, Ph.D.

Studied the visual system in primates.

GRADUATE STUDENT RESEARCH ASSISTANT 6/1999-8/1999

Department of Molecular Biology

Vanderbilt University

Nashville, TN

Advisor: Charles K. Singleton, Ph.D.

Researched JNK1 activity during thiamine deficiency in neuroblastoma cells.

TEST GRADER 5/1999

Measurement Incorporated

Nashville, TN

Graded standardized tests.

LIFE SCIENCES SUMMER UNDERGRADUATE RESEARCH

PROGRAM 6/1998-8/1998

University of Minnesota

St. Paul, MN

Advisor: Robert Jones, Ph.D.

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Researched drought tolerance in maize seedlings.

SUMMER RESEARCH OPPORTUNITY PROGRAM 6/1997-8/1997

Indiana University Purdue University at Indianapolis (IUPUI)

Indianapolis, IN

Advisors: William McBride, Ph.D. and Barbara Bowers, Ph.D.

Studied the effects of serotonin on alcohol-induced dopamine release.

MINORITY ACCESS TO RESEARCH CAREERS STUDENT 1997-1999


Nashville, TN

Advisor: E.L. Myles, Ph.D.

Conducted research to identify stress tolerant genes in glycine max.

CHEMISTRY TUTOR 1997-1999


Nashville, TN

Supervisor: Carlos Lee, Ph.D.

Tutored undergraduate students in general and organic chemistry.

HEALTH CAREERS OPORTUNITY PROGRAM 6/1996-8/1996


Nashville, TN

Hall counselor and tutor to high school and undergraduate students.

TEACHING EXPERIENCE:

ASSISTANT PROFESSOR OF BIOLOGY 1/16/2014-present


Courses: General Biology I and II for Biology majors, Neuropharmacology for graduate students, Cell

Biology for graduate students, Tennessee State University-Neuroscience Education and Research

Vanderbilt Experience (TSU-NERVE) seminar (professional development for biology and psychology

majors in the program designed to help them get PhDs in neuroscience)

ASSISTANT PROFESSOR OF BIOLOGY 8/1/2011-12/31/2013

Fisk University

Courses: Molecular Neuroscience, The Brain, Behavior, and Neuropharmacology, Independent Study:

Special Topics in Neuroscience, Biology Boot camp, Cell Biology for graduate and undergraduate

students

SCIENTIST-EDUCATOR FELLOW 10/2008-7/31/2011


Nashville, TN

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Brain and Behavior Module TA and Instructor:

Assisted the course director of the brain and behavior module course in School of Medicine

(course content includes medical neuroanatomy, psychiatry, medical pharmacology, and

neuropathology). Duties included formal lectures to medical students, answering questions from

students, helping students with brain dissections, writing and grading exams.

RESEARCH MENTOR, VANDERBILT SUMMER SCIENCE

ACADEMY Summer 2009


Nashville, TN

RESEARCH MENTOR, UNDERGRADUATE RESEARCH OPPORTUNITY PROGRAM

(UROP) 9/2006-12/2007

University of Michigan

Ann Arbor, MI

TEACHING ASSISTANT 1/2004

Neuroscience Graduate Program


Nashville, TN

Program Director: Elaine Sanders-Bush, Ph.D.

Teaching assistant as a graduate student for the Advanced Molecular Neuroscience course,

where I led lecture discussions for neuroscience graduate students.

CHEMISTRY TUTOR 1997-1999


Nashville, TN

Supervisor: Carlos Lee, Ph.D.

Tutored undergraduate students in general and organic chemistry.

UNDERGRADUATE RESEARCH MENTORSHIP

1. Larry McNary- SOARS undergraduate student at Tennessee State University

2. Zeljka Miletic-Langnahan – undergraduate student at Tennessee State University

3. Johnathan Fitzgerald – undergraduate TLSAMP student at Tennessee State University

4. Jazz'men C. Easton – undergraduate student: Honors Thesis at Tennessee State University

5. David Anderson – undergraduate TLSAMP student at Tennessee State University

6. David Battle – undergraduate student at Tennessee State University

7. Shaniqua Jones – undergraduate student at Tennessee State University

8. Casey Vincent – undergraduate student at Tennessee State University

9. Kiara Williams – undergraduate TLSAMP student at Tennessee State University

10. Gerald Nwosu – undergraduate MARC U-STAR student Tennessee State University (PhD student at

Meharry Medical School)

11. Monique Marshall – undergraduate student at Tennessee State University (Research assistant at

Vanderbilt University)

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12. Sandra Girgis – undergraduate student at Tennessee State University

13. Mia Krout – undergraduate student at Middle Tennessee State University (Currently a PhD student

at the University of Illinois at Chicago)

14. Quzonna Reed – undergraduate student at Fisk University

15. Leonel Herrera-Flores – undergraduate MARC U-STAR student at Tennessee State University

16. Ashlyn Furkins – undergraduate student at Tennessee State University

17. Ashley Hicks – undergraduate TLSAMP student at Tennessee State University

18. Sierra Fitzgerald – undergraduate student at Fisk University

19. Prince Addai – undergraduate student at Fisk University

20. Michael Saarah – undergraduate student at Fisk University

21. Sandra Okoro – undergraduate student at Fisk University

22. Ebenezer Nkrumah – undergraduate student at Fisk University

23. Marcus Crayton – undergraduate student at Fisk University

24. Keyon Jiles – high school student from Milwaukee, WI

25. Lauren Vaslin – undergraduate summer student at Clark Atlanta

26. Franklin Echevarria- undergraduate summer student (Post-doc at Case Western Reserve University)

27. Nathan Wallace – undergraduate student at Vanderbilt University (Case Western Reserve University

graduate student)

28. Mark Etherington- undergraduate student at Vanderbilt University (Penn State medical student)

29. Erin Watt – graduate student at Vanderbilt University

30. Chris Muller – graduate student at Vanderbilt University

31. Danielle Roberson- undergraduate student at the University of Michigan

32. Caitlin Shannon- undergraduate student at Vanderbilt University

MENTORING AND PRESENTATION SUPPORT

1. Aliyah Muhammad (2018-present) TSU-NERVE Scholar

2. Brianna McCollum (2018-present) TSU-NERVE Scholar

3. Shelby Davis (2018-present) TSU-NERVE Scholar

4. Autumn Brunson (2018-present) TSU-NERVE Scholar

5. Anna Cooper (2018) TSU-NERVE Scholar

6. Simone Compton (2017-present) TSU-NERVE Scholar

7. Elyse Lang (2017-present) TSU-NERVE Scholar

8. Jazz Fields (2017-present) TSU-NERVE Scholar

9. David Battle (2017-present) TSU-NERVE Scholar

10. Miki Wilkinson (2016) TSU-NERVE Scholar

11. JorDyne Jackson (2015-2017) TSU-NERVE Scholar

12. Renita Jones (2015-2017) TSU-NERVE Scholar

13. Erin Chatman (2015-2017) TSU-NERVE Scholar

14. Zakia Lowery (2016-present) TSU-NERVE Scholar

15. Idris Kosoko (2016-present) TSU-NERVE Scholar

16. Loni Parrish (2016-present) TSU-NERVE Scholar

17. Courtney Newman (2016-present) TSU-NERVE Scholar

18. Jordan Spencer (2016-present) TSU-NERVE Scholar

19. Romin Geiger (2016-2017) TSU-NERVE Scholar

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GRADUATE COMMITTEES

1. Ally Hasbun, Ph.D. Advisor, Tennessee State University 2018-present

2. Aniska Ramsay, Ph.D. Co-Adviosr, Tennessee State University 2018-present

3. Musarrat Maisha, M.S. Advisor, Tennessee State University 2018-present

4. Sylvia Driggins, Ph.D. Committee member, Tennessee State University 2015-2018

5. Letimicia Fears, Ph.D. Co-Advisor, Tennessee State University

(Currently a Post-doc at Vanderbilt University) 2014-2017

6. Marybeth Curtis, M.S. Advisor, Tennessee State University

(Currently a Ph.D. student at Temple University) 2014-2016

7. Bipradas Roy, M.S. Advisor, Tennessee State University

(Currently a Ph.D. student at Wayne State University) 2014-2016

8. Richard Yorke, Ph.D. Committee member, Tennessee State University 2014-2016

9. Cassandra Bowers, M.S. co-Advisor, Tennessee State University 2014-2015

10. Bobby Jones Jr., Fisk-Vanderbilt M.S. to Ph.D. Bridge Program

(Currently a Ph.D. student at Meharry Medical College) 2013-2015

11. Melanie Brady, M.S. Advisor, Fisk-Vanderbilt M.S. to Ph.D. Bridge

Program (Currently a Ph.D. student at Yale University) 2012-2014

12. Renita King, M.S. Advisor, Fisk-Vanderbilt M.S. to Ph.D. Bridge

Program 2011-2013

13. Sawandi Salimu, Master’s Program, Cal State Dominguez Hill 2013

14. Erica Smith, Biology Master’s Program, Fisk University 2011-2012

15. Naccolaine Ridgeway, Master’s Program, Fisk University 2011-2012

16. Stewart Voit, Chemistry Mater’s Program, Fisk University 2011

UNIVERSITY COMMITTEES

1. TSU Honors College Assistant Dean Search Committee 2017-2018

2. Biology MS Program Review Committee 2017-2018

3. MARC U-STAR Advisory Committee 2016-present

4. TSU Honors College Advisory Board 2016-present

5. Co-Director of the TSU NERVE Program 2016-present

6. Biosafety Committee 2015-present

7. College of Life and Physical Sciences Consortium Advisor 2015-present

8. Biology PhD Program Review Committee 2015-2016

9. Physical Therapy Advisory Committee 2015-present

10. Recruitment/Public Relations/Activities/Amenities Committee 2014-present

11. Assessment/Curriculum and Instruction/Library/Advisement Committee 2014-present

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PROFESSIONAL SOCIETIES

1. Society for Neuroscience (SfN)

2. Middle Tennessee Society for Neuroscience

3. Beta Kappa Chi National Scientific Honor Society

4. Tennessee Physiology Association

5. American Society for Pharmacology and Experimental Therapeutics

FACULTY DEVELOPMENT

1. Advisement Workshop at TSU Avon Williams Campus, January 10, 2018.

2. Workshop presented by Dr. Saundra McGuire on Advisement and Mentoring, August 25, 2017.

3. Workshop entitled “Andragogy: A Key to Understanding the Adult Learner”, TSU Avon Williams

campus, Friday, March 31st, 2017.

4. Professional Development workshop on Research and Mentoring of Early Career STEM Faculty at

HBCUs by Quality Education for Minorities (QEM), Baltimore, MD, February 26-27th, 2016.

5. Workshop for the National Science Foundation (NSF)’s Faculty Early Career (CAREER)

Development Program by the Quality Education for Minorities (QEM) Network, Baltimore, MD,

March 6-7, 2015.

6. Tenure and Promotion Portfolio Workshop, Tennessee State University, April 10, 2015.

7. The Sloan-C Certificate Program for an Online Teaching Certificate, 2012.

8. Natural Science Mathematics and Business Faculty Retreat, May 8th, 2012.

9. Quality Education for Minorities (QEM) Network Proposal Development Workshop for Research

Initiation Awards (RIA) Track in the National Science Foundation’s Historically Black Colleges and

Universities Undergraduate Program (HBCU-UP) and its Tribal Colleges and Universities Program

(TCUP), January 27-28th, 2012.

AWARDS AND HONORS

1. NatSci Council on Diversity and Community (CDC) Seminar Speaker at Michigan State

University, 2017-2018

2. Keynote Lecturer for Tennessee State University’s Biological Sciences Day, April 8, 2014

3. Health Emotions Annual Meeting Travel Award Winner 2007

4. Postdoctoral Training in the Biology of Drug Abuse University of Michigan, 2006

5. NIGMS Workshop on Achieving Scientific Excellence through Diversity, May 6-7, 2001

6. Golden Key National Honor Society

7. Phi Kappa Phi National Honor Society

8. 3rd place at Tennessee State University’s Research Day, 1999

9. 1st place at Beta Kappa Chi National Conference, 1999

10. Honorable Mention at Tennessee Academy of Science, 1999

11. Best paper presentation at Tennessee Academy of Science, 1998

12. All-American Scholar Collegiate Award

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13. National Collegiate Minority Leadership Award

14. Who’s Who Among American College Students

15. National Dean’s List, 1995-1999

16. Tennessee State University Honors Program, 1995-1999

17. Wal-Mart Scholarship, 1995

18. Civitan Club Scholarship, 1995

19. R.C. Byrd Scholarship, 1999

20. Presidential Scholarship at Tennessee State University, 1995-1999

Grant Support (Past and Current)

Descriptive Title of Project Status

Status

Date

Received

Date

Requested

Amount

1. NIH R25, TSU NERVE Program,

Program Co-Director Awarded 04/01/2015 $800,551

2. National Science Foundation (NSF)

Research Initiation Award, PI

Identifying changes in serotonin receptor

function due to naturally

occurring single nucleotide polymorphisms

(SNPs) Awarded 08/10/2012 03/12/2012 $200,000

3. National Science Foundation (NSF)

Research Initiation Award Grant for


function due to naturally occurring single

nucleotide polymorphisms (SNPs) Awarded 09/01/2015 07/09/2015 $39,164

Awarded 04/01/2014 02/19/2014 $88,612

4. NIDA Postdoctoral Training Grant, Awarded

University of Michigan, Fellow 2006-2008

5. NIGMS MARC Predoctoral Fellowship, PI Awarded 2003-2005

6. University Graduate Fellowship,

Vanderbilt University, PI Awarded 2000-2004 $15,000

7. National Science Foundation Predoctoral

Fellowship, PI 2000-2003 $28,000

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Grants Submitted

Descriptive Title of Project Status

Status

Date

Received

Date

Requested

Amount

8. Elucidation of the Serotonin 2C Receptor’s

Role in Fat Deposition in Chickens Pending 9/1/2018

9.

CAREER:Characterizing how the human

serotonin 2C receptor activates the

JAK/STAT pathway Pending 08/09/2018 07/18/2018 $933,299

10. MRI: Acquisition of PALM MicroBeam

Laser Microdissection & Pressure

Catapulting System to be Used as a

University-Wide Shared Resource for

Research and Training at Tennessee State Declined 09/27/2017 01/10/2017 $212,018

11. MRI:Acquisition of PALM MicroBeam




Research and Training at Tennessee State Withdrawn 01/12/2017 01/05/2017 $212,018





Research and Training at Tennessee State Withdrawn 01/12/2017 01/10/2017 $212,018





Research and Training at Tennessee State Declined 06/16/2016 01/13/2016 $211,232

14. Characterization of JAK/STAT pathway

activation by the human serotonin 2C

receptor Declined 03/10/2016 11/16/2015 $961,357

15. CAREER:Characterization of activation of

the JAK/STAT pathway by the human

serotonin 2C receptor Declined 10/07/2015 07/22/2015 $961,355

Awarded 09/01/2015 07/09/2015 $39,164

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16. Research Initiation Award Grant for



nucleotide polymorphisms (SNPs)

Awarded 04/01/2014 02/19/2014 $88,612

17. Research Initiation Award Grant for



nucleotide polymorphisms (SNPs) Awarded 08/10/2012 03/12/2012 $200,000

JOURNAL/EDITOR AND GRANT REVIEWER

1. LOJ Pharmacology & Clinical Research (LOJPCR) Editorial Committee

2. NSF: Office of Advanced Cyberinfrastructure (OAC) grant reviewer, 2018

3. External Reviewer for Vanderbilt University’s Initiative for Maximizing Student Development

(IMSD) Program, April 24-25th, 2018

4. NSF: NRT grant reviewer, 2016-present

5. Cellular and Molecular Biology Journal: Reviewer

6. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics: Reviewer

PUBLICATIONS

1. Letimicia Fears, Marybeth Curtis, Terrance Johnson, and Hugh Fentress. Pharmacological

properties of Chromobacterium violaceum violacein at the human serotonin 2C Receptor. EC

Pharmacology and Toxicology 7.2 (2019), 103-111.

2. Mary E. Curtis, Letimicia S. Fears, Michael T. Ivy, Hugh M. Fentress. Activation of the

JAK/STAT pathway by the human serotonin 2C receptor (in revision).

3. Bipradas Roy, Samuel Nahashon, and Hugh Fentress. Regulation of the expression of the 5-HT2C

receptor in chicken brain by altering diets (in preparation).

4. Roy B, Curtis ME, Fears LS, Nahashon SN and Fentress HM (2016) Molecular Mechanisms of

Obesity-Induced Osteoporosis and Muscle Atrophy. Front. Physiol. 7:439. doi:

10.3389/fphys.2016.00439

5. HM Fentress, R Klar, JK Krueger, T Sabb, SN Redmon, NM Wallace, JK Shirey-Rice and MK

Hahn. Altered Regulation of Norepinephrine Transport and Behavior in Norepinephrine Transporter

Heterozygous Knockout Mice. Genes, Brain and Behavior. 9 OCT 2013 DOI: 10.1111/gbb.12084

6. Jana K. Shirey-Rice, Rebecca Klar, Hugh M. Fentress, Sarah N. Redmon, Tiffany Sabb, Jessica J.

Krueger, Nathan M. Wallace, Martin Appalsamy, Charlene Finney, Suzanna Lonce, André Diedrich,

David Robertson, Maureen K. Hahn. Norepinephrine Transporter A457P Knock-in Mice Display

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Key Features of Human Postural Orthostatic Tachycardia Syndrome. Dis. Model. Mech. April 4,

2013, doi: 10.1242/dmm.012203.

7. Qiang Wei*, Hugh M. Fentress*, Mary T. Hoversten, Limei Zhang, Elaine K. Hebda-Bauer,

Stanley J. Watson, Audrey F. Seasholtz, and Huda Akil. Early-Life Forebrain Glucocorticoid

Receptor Overexpression Increases Anxiety Behavior and Cocaine Sensitization. Biol Psychiatry.

2012 Feb 1; 71(3):224-31. (*equal contribution).

8. Hebda-Bauer EK, Pletsch A, Darwish H, Fentress H, Simmons TA, Wei Q, Watson SJ, and Akil H.

Forebrain glucocorticoid receptor overexpression increases environmental reactivity and produces a

stress-induced spatial discrimination deficit. Neuroscience. Aug 25;169(2):645-53. Epub 2010 May

31.

9. Maureen K. Hahn, Jennifer Blackford, Kirsten Haman, Michelle Mazei-Robison, Harish C. Prasad,

Angela Steele, Lisa Hazelwood, Hugh Fentress, Regina Myers, Randy D. Blakely, Elaine Sanders-

Bush, and Richard Shelton. Multivariate Permutation Analysis Associates Multiple Polymorphisms

With Subphenotypes Of Major Depression. Genes, Brain and Behavior. 7: 487-495, 2008.

10. Hugh M. Fentress, Ellinor Grinde, Joseph E. Mazurkiewicz, Jon R. Backstrom, Katharine Herrick-

Davis, and Elaine Sanders-Bush. Pharmacological Properties of the Cys23Ser Single Nucleotide

Polymorphism in Human 5-HT2C Receptor Isoforms. Pharmacogenomics J. 5:244-54, 2005.

11. Elaine Sanders-Bush, Hugh Fentress, Lisa Hazelwood. 5-HT2 Receptors: Molecular and Genomic

Diversity. Mol. Interv. 3: 319-330, 2003.

12. James J.-L. Wang, Zhaolin Hua, Hugh M. Fentress, and Charles K. Singleton. JNK1 is inactivated

during thiamine deficiency-induced apoptosis in human neuroblastoma cells. Nutr. Biochem. 11:208-

215, 2000.

ABSTRACTS

1. Mussarat Maisha, Marybeth Curtis, Zeljka Miletic Lanaghan, Michael Ivy, and Hugh Fentress.

Phosphorylation of STAT3 by Human Serotonin 2C Receptor. Experimental Biology Annual

Meeting (ASPET), April 6-9th, 2019.

2. Letimicia Fears, Terrance Johnson, and Hugh M. Fentress. Investigating the Pharmacological

Effects of Chromobacterium violaceum Violacein at the Human Serotonin 2C Receptor. American

Society for Microbiology, June 1-5, 2017.

3. Gerald Nwosu, Mia Krout, Quzonna Reed, Michael T. Ivy and Hugh M. Fentress. Generation and

Characterization of the Proline108Serine Single Nucleotide Polymorphism in the Human Serotonin

2C Receptor. Tennessee State University 38th Annual University Wide Research Symposium, April

17-21, 2017 (won first place).

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4. Letimicia S Fears, Mary E. Curtis, Terrance L. Johnson, and Hugh M. Fentress. Investigating the

Effects of Chromobacterium violaceum Violacein at the Human Serotonin 2C Receptor. Society for

Neuroscience annual meeting, San Diego, CA, November 11-16, 2016.

5. Letimicia S Fears, Mary E. Curtis, Terrance L. Johnson, and Hugh M. Fentress. Pharmacological

Properties of Chromobacterium violaceum Violacein at the Human Serotonin 2C Receptor.

Experimental Biology annual meeting, San Diego, CA, April 2-6, 2016.

6. Mary E. Curtis, Letimicia S. Fears, Michael T. Ivy and Hugh M. Fentress. Constitutive

Phosphorylation of STAT3 by the Human Serotonin 2C Receptor. Experimental Biology annual

meeting, San Diego, CA, April 2-6, 2016.

7. Bipradas Roy, Samuel Nahashon, and Hugh M. Fentress. Characterization and expression of the

serotonin 2C receptor in chicken. Tennessee State University 38th Annual University Wide Research

Symposium, April 4-8, 2016.

8. Gerald Nwosu, Mia Krout, Quzonna Reed, Michael T. Ivy and Hugh M. Fentress. Generation and

Characterization of the Proline108Serine Single Nucleotide Polymorphism in the Human Serotonin

2C Receptor. Tennessee State University 38th Annual University Wide Research Symposium, April

4-8, 2016.

9. Ashley Hicks, Mary E. Curtis, Letimicia Fears, Michael T. Ivy and Hugh M. Fentress. Constitutive

Activation of the STAT3 by the Human Serotonin 2C Receptor (5-HT2CR). Tennessee Louis Stokes

for Alliance for Minority Participation (TLSAMP) Annual conference, Knoxville, TN. February 25-

27th, 2016.

10. Mary E. Curtis, Letimicia S. Fears, Michael T. Ivy and Hugh M. Fentress. Activation of the

JAK/STAT Pathway through the Human Serotonin 2C Receptor. Society for Neuroscience Annual

Meeting, October 17-21, 2015.

11. Leonel Herrera-Flores, Bipradas Roy, Ashlyn Furkins, Mary E. Curtis, Letimicia S. Fears, Michael

T. Ivy and Hugh M. Fentress. Impact of the Proline280Leucine single nucleotide polymorphism in

the human serotonin 2C receptor on activation of the JAK/STAT pathway. Tennessee Academy of

Science Annual meeting, Belmont University, April 18, 2015.

12. Mary E. Curtis, Letimicia S. Fears, Ashly Hicks, Michael T. Ivy and Hugh M. Fentress. Activation

of the JAK/STAT Pathway through the Human Serotonin 2C Receptor. Tennessee State University

37th Annual University Wide Research Symposium, March 30-April 3, 2015 (won second place).

13. Letimicia S Fears, Mary E. Curtis, Terrance L. Johnson, and Hugh M. Fentress. Investigation of the

Effects of Violacein on Human Serotonin 2C Receptors. Tennessee State University 37th Annual

University Wide Research Symposium, March 30-April 3, 2015 (won second place).

14. Leonel Herrera-Flores, Bipradas Roy, Ashlyn Furkins, Michael T. Ivy and Hugh M. Fentress.

Generation and Characterization of the Proline280Leucine Single Nucleotide Polymorphism in the

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Human Serotonin 2C Receptor. Tennessee State University 37th Annual University Wide Research

Symposium, March 30-April 3, 2015.

15. Mary E. Curtis, Letimicia S. Fears, Ashly Hicks, Michael T. Ivy and Hugh M. Fentress.

Constitutive Activation of the JAK/STAT Pathway through the Human Serotonin 2C Receptor.

Emory STEM Symposium, March 25-27, 2015.

16. Letimicia S Fears, Mary E. Curtis, Terrance L. Johnson, and Hugh M. Fentress. Investigation of the

Effects of Violacein on Human Serotonin 2C Receptors. Emory STEM Symposium, March 25-27,

2015.

17. Ashley Hicks, Marybeth Curtis, Letimicia Fears, Michael Ivy, and Hugh M. Fentress. Activation of

the JAK/STAT Pathway by the Human Serotonin 2C Receptor (5-HT2CR). Tennessee Louise

Stokes Alliance for Minority Participation Annual Meeting, February 26-27, 2015.

18. Melanie V. Brady and Hugh M. Fentress. Characterizing the human SNP, T419A, of the 5-HT2CR.

Fisk University 15th Annual Research Symposium, Nashville, TN, April 4, 2013.

19. Renita N. King, Ron B. Emeson, and Hugh M. Fentress. Characterization of the Epitope Tagged

Serotonin 2C Receptor and the MAP Kinase Signaling Pathway. Fisk University 15th Annual

Research Symposium, Nashville, TN, April 4, 2013.

20. Maureen K. Hahn, Jana K. Shirey-Rice, Rebecca Klar, Hugh M. Fentress, Sarah N. Redmon,

Tiffany Sabb, Jessica J. Krueger, Nathan M. Wallace, Martin Appalsamy, Charlene Finney, Suzanna

Lonce, André Diedrich, David Robertson. Norepinephrine Transporter A457P Knockin Mice

Display Tachycardia and Anxiety-like Behavior. The Tenth International Catecholamine

Symposium, Pacific Grove, CA, Sept. 9-13, 2012.

21. Jana K. Shirey-Rice, Rebecca Klar, Hugh M. Fentress, Sarah N. Redmon, Jessica J. Krueger,

Nathan M. Wallace, Martin Appalsamy, Charlene Finney, Suzanna Lonce, André Diedrich, David

Robertson, and Maureen K. Hahn. Norepinephrine transporter A457P knockin mice display

tachycardia and anxiety-like behavior. American College of Neuropsychopharmacology 50th

Annual Meeting, Waikoloa, HI, 2011.

22. Rebecca Klar, Jana K. Shirey-Rice, Hugh M. Fentress, Sarah N. Redmon, Jessica J. Krueger,

Nathan M. Wallace, Martin Appalsamy, Charlene Finney, Suzzana Lonce, André Diedrich, David

Robertson, and Maureen K. Hahn. Norepinephrine transporter A457P knockin mouse: A model of a

gene variant associated with comorbid cardiovascular and psychiatric disorders. Society for

Neuroscience Annual Conference, 2011.

23. H. M. Fentress, J. K. Krueger, J. K. Shirey, M. K. Hahn. Heterozygous norepinephrine transporter

knock-out mice display increased anxiety-like behavior and cognitive dysfunction. Society for

Neuroscience Annual Conference, 2010.

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24. Fentress, H, Krueger, JJ, and Hahn, MK. Norepinephrine Transporter Hypofunction in Attention

Deficit Hyperactivity Disorder. American College of Neuropsychopharmacology, 48nd annual

meeting, Hollywood, FL, Dec. 6-10, 2009.

25. Franklin D. Echevarria, Hugh M. Fentress, Jessica J. Krueger, and Maureen K. Hahn. NET

Deficiency in Attention Deficit Hyperactivity Disorder. Vanderbilt Summer Science Academy,

Nashville, TN, 2009.

26. Elaine K. Hebda-Bauer, Amy E. Pletsch, Hala Darwish, Hugh Fentress, Tracy A. Simmons, Qiang

Wei, Stanley J. Watson, and Huda Akil. Overexpression of a Stress Gene Alters Environmental

Reactivity. Midwest Nursing Research Society Conference, 2008.

27. H. Fentress, Q. Wei, M. T. Hoversten, S. J. Watson, H. Akil. Gene Expression Differences Due to

Inducible Overexpression of Glucocorticoid Receptor in the Forebrain of Mice: Early Versus

Lifetime Overexpression. Society for Neuroscience Annual Conference, 2007.

28. Hugh M. Fentress, Lisa A. Hazelwood, Regina L. Myers, and Elaine Sanders-Bush.

Characterization of Naturally Occurring Polymorphisms in the Human Serotonin 5-HT2A/2C receptor

genes. Middle TN Chapter of the Society for Neuroscience, Nashville, TN, 2003.

29. Hugh Fentress and Elaine Sanders-Bush. Characterization of a Cys23Ser Polymorphism in the

Human Serotonin 2C Receptor. Society for Neuroscience Annual Conference, 2002.

30. Hugh Fentress, D. Long, C. Caudle, and E. Lewis Myles. Nucleotide sequences of stress tolerant

genes in glycine max. Journal of the Tennessee Academy of Science volume 74, numbers3-4, 1999.


genes in glycine max. TSU 21st annual University Wide Research Symposium, 1999.


genes in glycine max. Beta Kappa Chi Scientific Honor Society National Conference, 1999.

33. Hugh Fentress, M. Ashari, E. Myles, B. Mallory, D. Long, and C. Caudle. Identification of stress

tolerant genes in glycine max. Journal of the Tennessee Academy of Science volume 73, number 3-

4, 1998.


tolerant genes in glycine max. Beta Kappa Chi Scientific Honor Society National Conference, 1998.


tolerant genes in glycine max. TSU 20th Annual University Wide Research Symposium, 1998.

36. Hugh Fentress, Jeff Roessler, Josh Soldo, Robert Jones. Comparison of Colorimetric assay and 14C-zeatin radioisotopic assay for cytokinin oxidase in maize seedlings. The National Minority

Research Symposium, 1998.

http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=81efc3b0-f695-48d7-afc4-3a48a601607c&cKey=d0968c25-b1c5-4a93-a500-aba7357193a9

http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=81efc3b0-f695-48d7-afc4-3a48a601607c&cKey=d0968c25-b1c5-4a93-a500-aba7357193a9

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genes in glycine max. Tennessee Academy of Science, 1998.

38. H. M. Fentress, B.J. Bowers, and W.J. McBride. The effects of serotonin on alcohol induced

dopamine release. The National Minority Research Symposium, 1997.

INVITED LECTURES

1. Activation of the JAK/STAT Pathway by the Human Serotonin 2C (5-HT2C) Receptor. Research and

Methods Course, Tennessee State University, September 19, 2018

2. One Minority Neuroscientist’s Perspective: Diversity in STEM – Is it Important? Michigan State

University, NatSci Council on Diversity and Community (CDC), April 6, 2018.

3. The Serotonin 2C Receptor: roles in a new signaling mechanism, antipsychotic drug response, and

its role in obesity. Michigan State University, Department of Physiology, April 5, 2018.

4. Activation of the JAK/STAT Signaling Pathway by the Human Serotonin 2C Receptor. TSU Honors

Educational Discovery Presentations, February 6, 2018.

5. Activation of the JAK/STAT Pathway by the Human Serotonin 2C (5-HT2C) Receptor. Tennessee

State University Seminar. September 23, 2016.

6. Constitutive Phosphorylation of STAT3 by the Human

5-HT2C Receptor. DIDARP Seminar. Meharry Medical College. March 30, 2016.

7. Preparing Scholars for the pursuit of research careers in academia, government and industry. Getting

Back 2 Business Presentation to the Department of Health and Human Services, Tennessee State

University Research and Sponsored Programs. March 15, 2016.

8. Activation of the JAK/STAT pathway by the human serotonin 2C (5-HT2C) receptor. Tennessee

Physiology Society Annual Meeting. January 23, 2015.

9. A tale of two neurotransmitter systems: norepinephrine and serotonin. Tennessee State University

Biological Sciences Day Keynote Lecturer. Nashville, TN, April 8, 2014.

10. Identifying changes in serotonin receptor function due to naturally occurring single nucleotide

polymorphisms (SNPs). Seminar Tennessee State University, Nashville, TN, November 19, 2013.

11. Both knocking “out” and “in” the norepinephrine transporter leads to increased anxiety-like

behavior. Seminar, Tennessee State University, Nashville, TN, March 1, 2013.

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12. How deleting genes in mice has revealed a key role for norepinephrine in both anxiety and

cognition. Seminar, Fisk University, Nashville, TN January 20, 2011.

13. Heterozygous norepinephrine transporter knockout mice display increased anxiety-like behavior and

cognitive dysfunction. Seminar, Tennessee State University, Nashville, TN September 17, 2010.

14. Genetic analysis of 5-HT2C receptors in unipolar depression. Seminar, Harvard Children’s Hospital

Boston, Boston, MA, April 2005.

15. Genetic analysis of 5-HT2C receptors in unipolar depression. NIAAA/PARC Research Seminar,

OHSU, Portland, OR, March 2005.

16. Genetic analysis of 5-HT2C receptors in unipolar depression. Seminar, University of Michigan, Ann

Arbor, MI, March 2005.

17. Genetic analysis of 5-HT2C receptors in unipolar depression. Seminar, Tennessee State University,

Nashville, TN, 2005.

18. Molecular diversity of the 5-HT2C receptor. Seminar at Tennessee State University, Nashville, TN,

2003.

19. First Annual Levi Watkins, Jr. Lecture on Diversity in Medical Education. Vanderbilt University,

Nashville, TN, 2002: Gave remarks and thoughts on the importance of diversity at Vanderbilt

University.

20. Nucleotide sequences of stress tolerant genes in glycine max. Tennessee Academy of Science,

Clarksville, TN, 1999.

21. Nucleotide sequences of stress tolerant genes in glycine max. TSU 21st annual University Wide

Research Symposium, Nashville, TN, 1999.

22. Identification of stress tolerant genes in glycine max. Tennessee Academy of Science, Clarksville,

TN, 1998.

23. Identification of stress tolerant genes in glycine max. Beta Kappa Chi Scientific Honor Society

National Conference, 1998.

24. Identification of stress tolerant genes in glycine max. TSU 20th Annual University Wide Research

Symposium, 1998.

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SKILLS AND TECHNIQUES

SERVICE AND ACTIVITIES

1. Nolensville Food Pantry, January 24, 2018

2. External Reviewer for Vanderbilt University’s Initiative for Maximizing Student Development

(IMSD) Program, April 24-25th, 2018

3. Judge at Meharry Medical College’s 62ndAnnual Student Research Day, March 14, 2018.

4. Presented “Life as a Neuroscientist” to Kindergarten class at Mill Creek Elementary in Nolensville,

TN, March 16, 2017.

5. Judge at Meharry Medical College’s 61st Annual Student Research Day, March 15, 2017.

6. Tutor in the Boswell Tutorial Center, Spring 2017.

7. Presented “Life as a Neuroscientist” to Lake Providence Missionary Baptist Church Summer

Enrichment Program (K-8), June 27, 2016.

8. Tiger tutoring tutor, Tennessee State University, Spring 2016.

9. Observed and critiqued genetic presentations at Cane Ridge High School, May 12, 2015.

Molecular Biology

RNA Isolation/Amplification

RT-PCR

PCR-site directed mutagenesis

Pyrosequencing/genotyping

Pharmacological Techniques

Radioligand Binding Assay

Competition Binding Assay

Phosphoinositide Hydrolysis Assay

Transport Assay

Behavioral Tests

Novel Object Recognition

Cocaine Sensitization

Radial Arm Maze (12 and 8 arm)

Morris Water Maze

Open Field

Light-Dark

Tail Suspension

Elevated Plus Maze

Elevated Zero Maze

Novelty-Induced Hypophagia

Home Cage Behavior

Biochemical Techniques

Surface Biotinylation

Western Blotting

Kinase Assays

Cell culture

Mammalian Cell Culture

Stable and transient transfections

Other Skills/Techniques

Immunohistochemistry and

Immunocytochemistry

In situ Hybridization

Laser Capture Microdissection

Microarray Analysis

Perfusions

Cryostat sectioning

Microtome sectioning

Mouse colony maintenance

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10. Presented “Life as a Neuroscientist” to Cane Ride High School’s Science Club, May 12, 2015.

11. Judge at Tennessee State University’s 37th Annual University-Wide Research Symposium, March

30-April 3, 2015.

12. Judge at Meharry Medical College’s 59th Annual Student Research Day, March 18, 2015.

13. Judge at the Tennessee Louise Stokes Alliance for Minority Participation Annual Meeting, February

26-27, 2015.

14. Presented “Life as a Neuroscientist” at Shayne Elementary School second grade class, May 9, 2014.

15. Judge at Tennessee State University’s 36th Annual University-Wide Research Symposium, March

31-April 4, 2014.

16. Ran a wet brain table for kids at Vanderbilt University’s 2014 Brain Blast, March 1, 2014.

17. Gave Jack and Jill students from St. Louis, MO a tour of Vanderbilt University.

18. Presented “Life as a Neuroscientist” to the entire study body at Carter Lawrence Elementary Math

and Science Magnet School (showed neuroscience slides, played neuroscience games, showed them

sheep brains and fluorescent DNA gels), October 31, 2013.

19. Fisk University Honors Program Committee Member, Fall 2013

20. Judge at Tennessee State University’s 35th Annual University-Wide Research Symposium, 2013

21. Presented “Life as Neuroscientist” to first graders at Eakin Elementary (3/14/13)

22. Scored Critical Thinking Assessment Test (CAT) at Fisk University (5/10/12)

23. Presented “Life as a Neuroscientist” to kindergarten classes at Carter Lawrence Elementary

(4/27/12)

24. Judge at Fisk University’s Research Day 2012

25. Judge at Tennessee State University’s 34th Annual University-Wide Research Symposium, 2012

26. Judge for Tennessee State University’s 31st Annual University-Wide Research Symposium, 2009

27. Held discussion panel for high schools students visiting from St. Louis, MO, 2009

28. Society for Neuroscience (SfN)

29. Association of Black Professionals Administrators Faculty and Staff (ABPAFS), University of

Michigan

30. Health and Wellness Ministry, Bethel A.M.E. Church, Ann Arbor, MI

31. Associate Steward Board, Bethel A.M.E. Church, Ann Arbor, MI

32. Men of Action, Bethel A.M.E. Church, Ann Arbor, MI

33. Alliance for Cultural Diversity in Research (ACDR), Vanderbilt Univ. 2004-2005

34. Organization of Black Graduate and Professional Students (OBGAPS), Vanderbilt University, 1999-

2005

35. Diversity Strategic Planning Committee, Vanderbilt Univ., 2003-2005

36. Neuroscience Student Leadership Award Committee, Vanderbilt Univ., 2004-2005

37. Neuroscience Student Organization (NSO), Vanderbilt Univ., 2000-2005

38. NSO journal club coordinator, Vanderbilt Univ., 2000-2001

39. Health Care Ministry: Mt. Zion Baptist Church, Nashville, TN, 1999-2005

40. Tutor at Mt. Zion Baptist Church, Nashville, TN, 1999-2002

41. Vanderbilt University Conference on Neurogenomics: Building a Better Brain. (helped attendees

with registration and assisted them during the talks) May 20-23, 2001.

42. NIGMS Workshop on Achieving Scientific Excellence through Diversity. May 6-7, 2001

43. Minority Access to Research Careers (MARC) Advisory Committee, Tennessee State University

1999

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hugh m. fentress · 205 zina pitcher place ann arbor, mi advisor: huda akil, ph.d. studied drug...

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