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Heredity Mendel’s Laws S-B-8-1_Heredity PowerPoint

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Page 1: Heredity Mendel’s Laws S-B-8-1_Heredity PowerPoint

Heredity

Mendel’s Laws

S-B-8-1_Heredity PowerPoint

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Heredity

Source: http://en.wikipedia.org/wiki/Habsburg

S-B-8-1_Heredity PowerPoint

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How are traits inherited?

• Selective Breeding– Domestication of plants

• Higher yielding crops• Mature faster, set fruit earlier• Attractive fruit

– Domestication of animals• Desired behaviors• Desired qualities

Gray Wolf

http://animal.discovery.com/mammals/wolf/ http://www.akc.org/breeds/

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Gregor Mendel

• Born in 1822, Brno, Moravia (now the Czech Republic), the only son of a farming family

• Showed promise in school and entered the monastery to continue his education

• Went to the University of Vienna, studying physics and math

• Came back to the Abbey in Brno to teach and experiment in the garden

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Mendel’s Experiment

• Mendel investigates inheritance in pea plants for eight years.

• He chose peas because: – They are easy to cultivate.– They reproduced sexually.– They have easy to

distinguish traits.

http://www.scientificamerican.com/article.cfm?id=gene-behind-mendels-green&ref=rss

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Pisum sativum-The Pea

http://www.tutorvista.com/content/biology/biology-iii/heredity-and-variation/mendels-experiments.php

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Artificial Pollination

Removing Stamen from flower

Exposing Stigma and dusting with pollen

Covering the flower with bag and labeling

stem

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Monohybrid Cross

• Crossed Tall plants with Short plants, the parents or P

• Called the hybrid offspring, the First Filial, F1, generation

What would you expect the F1 Generation to look like?

X

F1

P

All offspring are tall.

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Rule of Dominance• recessive traits

– The trait that is not expressed, or hidden, in the F1 generation

• DOMINANT traits – The trait expressed in

hybrid offspring, the F1 generation

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The F2 Generation

Mendel allowed the F1 plants to self pollinate.

What would you expect the offspring to look like?

F1

P

F2

X

787 tall plants and 277 dwarf plants

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Rule of Unit Factors

Mendel’s Explanation• Individuals have two “heritable”

factors for a trait .• The two factors may or may not

contain the same information:– Homozygous individuals have

identical factors .• TT or tt

– Heterozygous individuals have 2 different factors.

• Tt

F1

P

F2

X

TT

Tt

tt

TT ttTt Tt

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Genetics

Modern Genetics• Individuals have two copies of a

gene (one on each homologous chromosome).

• The various forms of a gene are called alleles:– Dominant alleles are expressed

when they are present.– Recessive alleles are expressed

only when the individual is homozygous for the gene form.

Dwarf allele

Tall allele

Genes at the same location

HOMOLOGOUS CHROMOSOMES

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Phenotypes vs. Genotypes

• Phenotypes refer to what is expressed or the organism’s outward appearance.– TT and Tt pea plant

will be over 6 feet tall.– tt pea plant will be

under 2 feet tall.

• Genotypes refers to the specific alleles that make up the organism.– A TT pea plant is

homozygous Tall while a tt pea plant is homozygous dwarf.

– A Tt pea plant is heterozygous Tall.

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THINK-PAIR-SHARE

1. If the black rabbit and the white rabbit were bred and all the offspring were black, what conclusion can you make?

2. If the hybrid offspring were allowed to mate, would you expect some of the litter to be white? Why?

Xhttp://www.countryfarm-lifestyles.com/raising-rabbits.html

http://athomepets.blogspot.com/2008/03/bunnies-born-for-easter-crowd.html

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THINK-PAIR-SHARE

1. Are the genotypes homozygous dominant, homozygous recessive, or heterozygous?• DdFF• RrYy• LLww• ggSs

2. The letters used in genotypes usually represent the dominant trait, e.g., Y-yellow seed and y-green seed. Decide on traits to represent the genotypes above, and describe the phenotypes.

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Law of SegregationMendel’s Explanation

• Alleles separate when forming gametes.

• Parents pass only one allele for each trait.

Modern Genetics• What process ensures

that alleles separate during gamete formation?

http://www-bcf.usc.edu/~forsburg/meiosis.html

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Dihybrid Cross

• Mendel repeated his experiment with plants that are bred true for two traits.

• He again allowed the F1 generation to self pollinate.

• Phenotypic ratio: 9:3:3:1

http://image.wistatutor.com/content/feed/u2044/Punnet%20square.gif

XP

F1

F2

32101108315

Y-Yellow

y-green

R-Round

r-wrinkled

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Law of Independent Assortment

Mendel’s Explanation• Traits are inherited

independently from one another.

Modern Genetics• What process ensures

that genes are randomly assorted among the gametes?

http://www.palaeos.com/Fungi/Lists/Glossary/GlossaryM.html

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Punnett Squares

• British biologist Reginald Punnett used a matrix to show the Laws of Segregation and Independent Assortment.

• The Punnett Square shows the probability of an offspring having a particular genotype.

http://image.wistatutor.com/content/feed/u2044/Punnet%20square.gif

Punnett Square of Dihybrid CrossParent Genotype RrYy

Gametes’ Genotype

Ga

me

tes

’ G

en

oty

pe

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Using Punnett Squares

Both parents are hybrids or heterozygous for

black fur.

♂Bb and ♀Bb

Step 1

Write the genotypes of the parents.

Black colored fur (B) is dominant to tan colored fur (b) in dogs. Suppose you cross two hybrid dogs with black fur. What are the possible phenotypes and genotypes of the puppies? What are the expected ratios for each genotype and phenotype?

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Using Punnett Squares

STEP 2

List the different gametes that each parent can

make.

To find the number of different gametes is 2n,

where n is the number of heterozygous gene pairs

Black colored fur (B) is dominant to tan colored fur (b) in dogs. Suppose you cross two hybrid dogs with black fur. What are the possible phenotypes and genotypes of the puppies? What are the expected ratios for each genotype and phenotype?

♂ gametes ♀ gametes B and b B and b

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Using Punnett Squares

STEP 3

Make a grid of horizontal and vertical lines.

Black colored fur (B) is dominant to tan colored fur (b) in dogs. Suppose you cross two hybrid dogs with black fur. What are the possible phenotypes and genotypes of the puppies? What are the expected ratios for each genotype and phenotype?

Since the male and female can make 2 different gametes the

grid will be 2 x 2.

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Using Punnett SquaresBlack colored fur (B) is dominant to tan colored fur (b) in dogs. Suppose you cross two hybrid dogs with black fur. What are the possible phenotypes and genotypes of the puppies? What are the expected ratios for each genotype and phenotype?

STEP 4

Put the gametes from one parent on the top and the other parent’s gametes on the side.

B b

B

b

♂ gametes

♀ g

ame

tes

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Using Punnett SquaresBlack colored fur (B) is dominant to tan colored fur (b) in dogs. Suppose you cross two hybrid dogs with black fur. What are the possible phenotypes and genotypes of the puppies? What are the expected ratios for each genotype and phenotype?

STEP 5

Fill in the boxes by copying the row and

column headings.

B b

B

b

BB Bb

Bb bb

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Using Punnett SquaresBlack colored fur (B) is dominant to tan colored fur (b) in dogs. Suppose you cross two hybrid dogs with black fur. What are the possible phenotypes and genotypes of the puppies? What are the expected ratios for each genotype and phenotype?

STEP 6

Determine the phenotypes of the possible offspring.

B b

B

b

BB BbBB Bb

Bb bb

1-BB

2-Bb

1-bb

3-Black colored fur

1-Tan colored fur

}

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THINK-PAIR-SHARE

1. What would a Punnett square look like for a monohybrid cross of a purple flowered pea plant allowed to self pollinate?

2. What are the genotypic ratios of the monohybrid cross?

http://en.wikipedia.org/wiki/File:Punnett_square_mendel_flowers.svg

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Problems with Two TraitsBlack colored fur (B) is dominant to tan colored fur (b) in dogs while smooth hair (h) is recessive to wire hair texture (H). Suppose you cross two hybrid dogs with black wiry coats. What are the possible phenotypes and genotypes of the puppies? What are the expected ratios for each genotype and phenotype?

Step 1

Write the genotypes of the parents.

Both parents are hybrids or

heterozygous for black and wiry coats.

♂BbHh and ♀BbHh

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Problems with Two Traits

STEP 2

List the different gametes that each parent can

make.

BH,

Step 1

Write the genotypes of the parents.

♂BbHh and ♀BbHh

♂ gametes

Bh bH bhBH, Bh, bH, bh

♂ gametesBH, Bh, bH, bh ♀ gametes

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Problems with Two TraitsSTEP 3

Make a grid of horizontal and vertical lines.

STEP 4Put the gametes from one parent on the top and the other parent’s gametes on the side.

BH

Bh

bH

bh

♀ g

amet

es

♂ gametes

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Problems with Two Traits

BH

Bh

bH

bh

♂ gametes

BH Bh bH bh

♀ g

amet

es

STEP 5Fill in the boxes by

copying the row and column headings.

BBHH BBHh BbHH BbHh

BBHh BBhh BbHh Bbhh

BbHH BbHh bbHH bbHh

BbHh Bbhh bbHh bbhh

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Problems with Two Traits

STEP 6Determine the phenotypes of

the possible offspring.

BBHH BBHh BBHhBbHH BbHH BbHhBbHh BbHh BbHh

Bbhh Bbhh

bbHh bbHh

bbhh

BBhh

bbHH

There is a 9 out of 16 chance that the offspring will have a black wiry coat.

There is a 3 out of 16 chance that the offspring will have a black smooth coat.

There is a 3 out of 16 chance that the offspring will have a wiry tan coat.

There is a 1 out of 16 chance that the offspring will have a smooth tan coat

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THINK-PAIR-SHARE

In guinea pigs, short hair (H) is dominant to long hair (h) and a short tail (T) is dominant to long tails (t). If a hybrid short hair and tail guinea pig is crossed with a long hair and tail guinea pig, what are the expected genotypic and phenotypic ratios?

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Step 1:Hybrid parent Purebred Parent

HhTt hhtt

Step 2: Hybrid gametes Purebred gametesHT, Ht, hT, ht ht

Step 3:Step 4: ht

HT Ht hT ht

Step 5:HhTt Hhtt hhTt hhtt

Step 6: HhTt

Hhtt

hhTt

hhtt

There is a 1 in 4 chance that the offspring will have short hair and tail

There is a 1 in 4 chance that the offspring will have short hair and a long tail

There is a 1 in 4 chance that the offspring will have long hair and a short tail

There is a 1 in 4 chance that the offspring will have long hair and tail

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• In pea plants Tall (T) is dominant to Short (t) and Purple flowers (P) are dominant to white (p). Cross two individuals who are heterozygous for both traits.

• What is the genotype ratio? Phenotype ratio?

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Complete Dominance

Every example so far has been complete dominance, when one allele completely masks another.

Sometimes it’s more complicated than that.

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Codominance

• Codominance is when two alleles are expressed simultaneously. They are dominant together.

• Ex. People with AB blood type, Roan Horses

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Incomplete Dominance

• Similar to codominance but neither allele is completely expressed.

• Example: a red flower and a white flower give rise to a pink flower. (red and white are being expressed incompletely.

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Sex Linked Traits

• Genes located on the X or Y chromosome (usually X)

• Males are more susceptible than Females. Why?

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Example:

• In guinea pigs Black hair (B) is dominant to white (b) and Short hair (H) is dominant to long hair (h). Cross a male that is homozygous recessive for fur color and heterozygous for hair length with a female that is heterozygous for both color and length. List the genotype and phenotype ratios.

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• In human blood typing, A and B are both dominant and O is recessive. If blood typing displays codominance, what would result from a cross between a male with AB and a female with AO.

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• Hemophilia is a sex-linked genetic disorder on the X chromosome. If a normal male was crossed with a carrier female, what are the possible genotypes of the offspring?

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X Y

X

Xh

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Which sex is most likely to have hemophilia?

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XX XY

XXh XhY