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Herbal Medicine Introduced Into the Basic Science Curriculum for 2nd
Year Medical Students
DJ Smith, Ph.D.
WVU-HSC
Coordinator Medical Pharmacology
Does instruction in herbal medicine have a place in a US medical school?
The Need for Instruction in Herbal Medicine
Herbal Remedies and Dietary Supplements are used extensively
Herbal products have medicinal value & toxicities & interactions with other herbs and drugs
Physicians need to be prepared to interact with patients using or requesting herbals
Introduction of Herbal Instructionat WVU-HSC
Early in the Medical Pharmacology lecture series Final 8 weeks of the Basic Science curriculum
Began in 2000
Students’ first formal exposure to herbal products
Objectives of the Learning Experience
Learn indications, side effects and contraindications for herbal remediesAppreciate herb-herb and herb-drug interactionsUnderstand the regulatory climate for dietary supplements and herbal remediesBegin to understand unique barriers to effective physician-patient interaction
Instructional Method
75 minutes of lecture delivered non-judgmentally, but factually
Small group discussion (2hrs) faculty facilitator & 8 students
Students prepared in advance of group discussions reviewing clinical cases using on-line and hard copy resources visiting herbal retail store
Evaluation of the Impact of the Instruction
Questionnaire given before and repeated after the instruction
Instrument was designed to evaluate students’ awareness, attitudes and content knowledge of herbal remedies
Also asked the extent to which they recommend future students be exposed to the material
The Case For Herbal Medicine
Tradition: used throughout historyNatural: perceived as gentler and saferCost: often less expensive than prescription medicineAccess: patient maintains control & no prescription necessarySynergism: a view that multiple ingredients working together yield better results
The Case Against Herbal Medicine
Lack of FDA Regulation and Oversight Lack of Dosage Standardization Potential for adulteration
Potential for toxicity and drug interactions: natural is not always saferMore effective therapy may be delayedMany herbs are not superior to prescription medicines
Regulatory Issues
Dietary Supplement Health Education Act (DSHEA) of 1994 Herbal products are legally food supplements Manufacturer may state usage and safety, but not make
curative claims Manufacturer alone is responsible for product safety FDA must prove product unsafe to remove it from the
market
Europe: Herbs regulated as pharmaceuticals
Saw Palmetto (Serenoa repens)
Used for prostatic obstructive symptoms
Dose: lipidosterolic extract 100mg (bid) or 1 g dried berries (tid) with foodSide effects: include nausea, diarrhea, headache impotenceCautions: include false negative PSAEffectiveness: equal to finasteride, but alpha-1 antagonists appear better
Introduction to Case Discussion(edited for brevity)
Athlete presents with SVT. Reluctantly admits drinking flavored beverage containing Ma Huang (Ephedra sinica) to enhance weight-lifting performance. Used two scoops for good measure. Observed till tachycardia resolved.Initial Questions What may account for his reluctance to admit using the
product? How do health care providers perpetuate the propensity
to withhold this information? & How do we change?
Facts and Assignment(discussion continues)
Active ingredients of Ma Haung is ephedra… Used extensively in Chinese herbal medicine…. Alkaloids are used in FDA approved meds… Life threatening CVS complications occur At a local herb store see what products contain ephedra, and evaluate the label informationQuestions: Is the label information adequate? What medical conditions preclude ephedra use? What herb-herb-drug interactions concern you?
Additional Questions
Many herbalists and patients believe that medical establishment has a prejudiced view of herbals. This creates a rift between patient and physician that is a barrier to effective communication.
Questions: Are US physicians prejudiced, and if so why? Are US physicians competent to make judgments
about herbals and to guide their patients, and if not how do we improve?
Further Consideration
The regulatory climate in the US is described…. In Europe herbs are regulated as phytopharmaceuticals, and they are widely prescribed in Europe and Asia… About 1/3 of the US population regularly take herbalsQuestions Advantages and disadvantages of US approach? Would you change the regulatory environment, how? How can patients be encouraged to share their use of
herbals with physicians?
Awareness of Herbal Remedies
60% did not have personal exposure
Gained knowledge of the extent of herb use in the US Q. What % of the US population uses herbal
remedies
Awareness of Herbal Remedies
Students significantly improved their recognition of herbal medicine Q. The contemporary definition of herbal medicine is?
Awareness of Herbal Remedies
Students discovered that there are credible sources for information on herbal medicine which are available in print form and on-line. Professional’s Handbook of Complementary and
Alternative Medicine, Fetro and Avila, Springhouse, 1999.
Herbal Research Foundation: www.herbs.org Herb Med www.herbmed.org Medline Plus
http://www.nlm.nih.gov/medlineplus/herbalmedicine.html ConsumerLab.com: http://www.ConsumerLab.com
Attitudes Toward Herbal Remedies
Students had strong opinions that changed very little with the learning experience
70% were skeptical of the reliance on herbals to the exclusion of Rx medsOverwhelmingly, herbals are to be used with cautionNearly all students accepted that their responsibility is to counsel patients regarding herbals
Attitudes Toward Herbal Remedies
Physicians should take a non-judgmental approach when counseling patients Q. I believe that it is _____ to take the position
that herbal remedies are “bad medicine”
Attitudes Toward Herbal Remedies
Physicians should take a non-judgmental approach when counseling patients Q. If a patient mentions the decision to take St
John’s Wort for depression, the physician should
Knowledge of Herbal Remedies
8 Content questions dealing with the regulatory climate, and therapeutic effects of specific herbals were asked.
Examined knowledge in a low impact manner, since performance on the questionnaire did not influence grade, nor were the students “asked” to study
Students gained appreciably
Knowledge of Herbal Remedies
Q. FDA regulates the manufacture, sale and therapeutic claims of herbal medicine as they do for prescription and non-prescription drugs
Knowledge of Herbal Remedies
Q. The herbal product used most frequently to treat migraine headache is:
General Observations and Conclusions
Our students have a high tolerance of the use of herbals, and are willing to counsel patients in a non-judgmental manner
They express a cautious view, but accept that there may be medical value when patients use some products appropriately
They report that exposure to this material is important and should be in the Medical Curriculum