heart failure educational tool
TRANSCRIPT
WHAT IS HEART FAILURE?Select from options A to D below
LEARNING ABOUT HEART FAILURE (HF)Heart failure is a common and potentially life-threatening condition, affecting more
than 20 million people worldwide – however few people fully understand heart failure
WHAT ISHEART FAILURE?
COMMONCAUSES
PREVALENCE& INCIDENCE
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENT URGENTNEED
A B C D
Where the heartcannot pump enough blood around the body
Where the heart’selectrical systembeats irregularly
Where blocked orclogged arteries limit
flow of blood to the heart
Where the heartis starved of blood and
oxygen, usually by a clot
Harrison’s ‘Principles of Internal Medicine’, Seventeenth Edition pages 1442 - 1455. Zannad F. et al. Heart failure burden and therapy. Europace. 2009;11:v1-v9. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53(7):557-73
WHAT IS HEART FAILURE?Select from options A to D below
LEARNING ABOUT HEART FAILURE (HF)Heart failure is a common and potentially life-threatening condition, affecting more
than 20 million people worldwide – however few people fully understand heart failure
WHAT ISHEART FAILURE?
COMMONCAUSES
PREVALENCE& INCIDENCE
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENT URGENTNEED
A B C D
Where the heartcannot pump enough blood around the body
Where the heart’selectrical systembeats irregularly
Where blocked orclogged arteries limit
flow of blood to the heart
Where the heartis starved of blood and
oxygen, usually by a clot
Harrison’s ‘Principles of Internal Medicine’, Seventeenth Edition pages 1442 - 1455. Zannad F. et al. Heart failure burden and therapy. Europace. 2009;11:v1-v9. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53(7):557-73
CorrectThis is known as
heart failure
WHAT IS HEART FAILURE?Select from options A to D below
LEARNING ABOUT HEART FAILURE (HF)Heart failure is a common and potentially life-threatening condition, affecting more
than 20 million people worldwide – however few people fully understand heart failure
WHAT ISHEART FAILURE?
COMMONCAUSES
PREVALENCE& INCIDENCE
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENT URGENTNEED
A B C D
Where the heartcannot pump enough blood around the body
Where the heart’selectrical systembeats irregularly
Where blocked orclogged arteries limit
flow of blood to the heart
Where the heartis starved of blood and
oxygen, usually by a clot
Harrison’s ‘Principles of Internal Medicine’, Seventeenth Edition pages 1442 - 1455. Zannad F. et al. Heart failure burden and therapy. Europace. 2009;11:v1-v9. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53(7):557-73
IncorrectThis is known as
arrhythmia
WHAT IS HEART FAILURE?Select from options A to D below
LEARNING ABOUT HEART FAILURE (HF)Heart failure is a common and potentially life-threatening condition, affecting more
than 20 million people worldwide – however few people fully understand heart failure
WHAT ISHEART FAILURE?
COMMONCAUSES
PREVALENCE& INCIDENCE
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENT URGENTNEED
A B C D
Where the heartcannot pump enough blood around the body
Where the heart’selectrical systembeats irregularly
Where blocked orclogged arteries limit
flow of blood to the heart
Where the heartis starved of blood and
oxygen, usually by a clot
Harrison’s ‘Principles of Internal Medicine’, Seventeenth Edition pages 1442 - 1455. Zannad F. et al. Heart failure burden and therapy. Europace. 2009;11:v1-v9. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53(7):557-73
Plaque
IncorrectThis is known asatherosclerosis
WHAT IS HEART FAILURE?Select from options A to D below
LEARNING ABOUT HEART FAILURE (HF)Heart failure is a common and potentially life-threatening condition, affecting more
than 20 million people worldwide – however few people fully understand heart failure
WHAT ISHEART FAILURE?
COMMONCAUSES
PREVALENCE& INCIDENCE
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENT URGENTNEED
A B C D
Where the heartcannot pump enough blood around the body
Where the heart’selectrical systembeats irregularly
Where blocked orclogged arteries limit
flow of blood to the heart
Where the heartis starved of blood and
oxygen, usually by a clot
Harrison’s ‘Principles of Internal Medicine’, Seventeenth Edition pages 1442 - 1455. Zannad F. et al. Heart failure burden and therapy. Europace. 2009;11:v1-v9. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53(7):557-73
IncorrectThis is known asa heart attack
COMMON CAUSES OF HEART FAILURE (HF)In most cases, heart failure does not have a single cause – there are a number of conditions
that may damage your heart and that could lead you to be diagnosed with heart failure
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
Select the silhouettes below
PREVALENCE& INCIDENCE
BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013
COMMON CAUSES OF HEART FAILURE (HF)In most cases, heart failure does not have a single cause – there are a number of conditions
that may damage your heart and that could lead you to be diagnosed with heart failure
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
Select the silhouettes below
PREVALENCE& INCIDENCE
BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013
Excess alcohol
COMMON CAUSES OF HEART FAILURE (HF)In most cases, heart failure does not have a single cause – there are a number of conditions
that may damage your heart and that could lead you to be diagnosed with heart failure
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
Select the silhouettes below
PREVALENCE& INCIDENCE
BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013
Damaged heart valves
COMMON CAUSES OF HEART FAILURE (HF)In most cases, heart failure does not have a single cause – there are a number of conditions
that may damage your heart and that could lead you to be diagnosed with heart failure
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
Select the silhouettes below
PREVALENCE& INCIDENCE
BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013
High blood pressure
COMMON CAUSES OF HEART FAILURE (HF)In most cases, heart failure does not have a single cause – there are a number of conditions
that may damage your heart and that could lead you to be diagnosed with heart failure
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
Select the silhouettes below
PREVALENCE& INCIDENCE
BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013
Arrhythmia/irregular heartbeat
COMMON CAUSES OF HEART FAILURE (HF)In most cases, heart failure does not have a single cause – there are a number of conditions
that may damage your heart and that could lead you to be diagnosed with heart failure
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
Select the silhouettes below
PREVALENCE& INCIDENCE
BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013
Atherosclerosis/blockedor clogged arteries
COMMON CAUSES OF HEART FAILURE (HF)In most cases, heart failure does not have a single cause – there are a number of conditions
that may damage your heart and that could lead you to be diagnosed with heart failure
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
Select the silhouettes below
PREVALENCE& INCIDENCE
BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013
Inflammationof the heart muscle
COMMON CAUSES OF HEART FAILURE (HF)In most cases, heart failure does not have a single cause – there are a number of conditions
that may damage your heart and that could lead you to be diagnosed with heart failure
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
Select the silhouettes below
PREVALENCE& INCIDENCE
BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013
Heart attack
COMMON CAUSES OF HEART FAILURE (HF)In most cases, heart failure does not have a single cause – there are a number of conditions
that may damage your heart and that could lead you to be diagnosed with heart failure
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
Select the silhouettes below
PREVALENCE& INCIDENCE
BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013
Weak heart muscle
WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?
FIND OUT MOREHeart failure is a major and growing�public health problem – select the silhouettes below
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
1 in 500 people
1 in 50 people
1 in 5 people
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
A
B
C
PREVALENCE& INCIDENCE
WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?
FIND OUT MOREHeart failure is a major and growing�public health problem – select the silhouettes below
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
1 in 500 people
1 in 50 people
1 in 5 people
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
A
B
C
PREVALENCE& INCIDENCE
1 in 500 peopleA
0.2% Incorrect
WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?
FIND OUT MOREHeart failure is a major and growing�public health problem – select the silhouettes below
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
1 in 500 people
1 in 50 people
1 in 5 people
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
A
B
C
PREVALENCE& INCIDENCE
1 in 50 peopleB 2% Incorrect
WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?
FIND OUT MOREHeart failure is a major and growing�public health problem – select the silhouettes below
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
1 in 500 people
1 in 50 people
1 in 5 people
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
A
B
C
PREVALENCE& INCIDENCE
1 in 5 people
20%
CorrectFor people aged 70–80, the lifetime
risk of developing heart failureis up to 1 in 5 in Europe
C
Dickstein et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008. European Heart Journal. 2008;29:2388–442
WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?
FIND OUT MOREHeart failure is a major and growing�public health problem – select the silhouettes below
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
1 in 500 people
1 in 50 people
1 in 5 people
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
A
B
C
PREVALENCE& INCIDENCE
More than 20 millionpeople suffer from heart
failure worldwide andthis number is increasing
More than 20 millionpeople suffer from heart
failure worldwide andthis number is increasing
20 mill
ion
wor
ldw
ide
Zannad F. et al. Heart failure burden and therapy. Europace. 2009;11:v1-v9. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53(7):557-73
WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?
FIND OUT MOREHeart failure is a major and growing�public health problem – select the silhouettes below
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
1 in 500 people
1 in 50 people
1 in 5 people
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
A
B
C
PREVALENCE& INCIDENCE
8,000,000
2030new cases by
By 2030, over eight millionpeople in the United States
(1 in every 33) will have heart failure
By 2030, over eight millionpeople in the United States
(1 in every 33) will have heart failure
Heidenreich et al. Forecasting the Impact of Heart Failure in the United States. Circulation: Heart Failure. 2013;6:606-619
WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?
FIND OUT MOREHeart failure is a major and growing�public health problem – select the silhouettes below
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
For people aged 40 and older,the lifetime risk of developing
heart failure is 1 in 5
1 in 500 people
1 in 50 people
1 in 5 people
SIGNS &SYMPTOMS
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
URGENTNEED
A
B
C
PREVALENCE& INCIDENCE
Incre
ased
hear
t
attac
k sur
vival
Incre
ased
hear
t
attac
k sur
vival
An aging population andan increase in the numberof people surviving heartattacks both contribute to
the rise in heart failure
An aging population andan increase in the numberof people surviving heartattacks both contribute to
the rise in heart failure
Aging
popu
lationAg
ing
popu
lation
Schocken et al. AHA Scientific Statement: Prevention of Heart Failure. Circulation. 2008;117:2544-2565. Mosterd A, Hoes, A. Clinical epidemiology of heart failure. Heart. 2007;93:1137-1146
ACUTE HEART FAILURE (AHF) EPISODES – A DOWNWARD SPIRALHeart failure is often fatal when patients have one or repeated AHFepisodes
SELECT NUMBERS TO VIEW
DOWNWARD SPIRALEvery episode results in worseninghealth and damage to vital organs,
such as the heart and kidneys,which decreases the chance
of the patient surviving another episode
‘It felt like I was drowning’
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
SIGNS &SYMPTOMS
URGENTNEED
PREVALENCE& INCIDENCE
12
34
12
34
Zannad F. et al. Heart failure burden and therapy. Europace. 2009;11:v1-v9. Irish Heart Foundation. Living well with heart failure patient booklet http://bit.ly/11FDqR6 Accessed August 2013. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53(7):557-73. Gheorghiade M et al. Rehospitalization for heart failure: problems and perspectives. Journal of the American College of Cardiology. 2013;61(4):391-403
ACUTE HEART FAILURE (AHF) EPISODES – A DOWNWARD SPIRALHeart failure is often fatal when patients have one or repeated AHFepisodes
SELECT NUMBERS TO VIEW
DOWNWARD SPIRALEvery episode results in worseninghealth and damage to vital organs,
such as the heart and kidneys,which decreases the chance
of the patient surviving another episode
‘It felt like I was drowning’
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
SIGNS &SYMPTOMS
URGENTNEED
PREVALENCE& INCIDENCE
12
34
SYMPTOMS
Breathlessness1
Incapacitation2
Fluid build-upWeight gain
34
As an AHF episodeapproaches, patientsexperience:
Zannad F. et al. Heart failure burden and therapy. Europace. 2009;11:v1-v9. Irish Heart Foundation. Living well with heart failure patient booklet http://bit.ly/11FDqR6 Accessed August 2013. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53(7):557-73. Gheorghiade M et al. Rehospitalization for heart failure: problems and perspectives. Journal of the American College of Cardiology. 2013;61(4):391-403. Mosterd A, Hoes, A. Clinical epidemiology of heart failure. Heart. 2007;93:1137-1146
ACUTE HEART FAILURE (AHF) EPISODES – A DOWNWARD SPIRALHeart failure is often fatal when patients have one or repeated AHFepisodes
SELECT NUMBERS TO VIEW
DOWNWARD SPIRALEvery episode results in worseninghealth and damage to vital organs,
such as the heart and kidneys,which decreases the chance
of the patient surviving another episode
‘It felt like I was drowning’
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
SIGNS &SYMPTOMS
URGENTNEED
PREVALENCE& INCIDENCE
12
34
SYMPTOMS
Breathlessness1
Incapacitation2
Fluid build-upWeight gain
34
As an AHF episodeapproaches, patientsexperience: Patients rushed to
the emergency roomfor urgent treatment
Zannad F. et al. Heart failure burden and therapy. Europace. 2009;11:v1-v9. Irish Heart Foundation. Living well with heart failure patient booklet http://bit.ly/11FDqR6 Accessed August 2013. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53(7):557-73. Gheorghiade M et al. Rehospitalization for heart failure: problems and perspectives. Journal of the American College of Cardiology. 2013;61(4):391-403. Mosterd A, Hoes, A. Clinical epidemiology of heart failure. Heart. 2007;93:1137-1146. Felker et al. Clinical trial of pharmacological therapies in acute heart failure syndromes. Circulation: Heart Failure. 2010;3:314-325
ACUTE HEART FAILURE (AHF) EPISODES – A DOWNWARD SPIRALHeart failure is often fatal when patients have one or repeated AHFepisodes
SELECT NUMBERS TO VIEW
DOWNWARD SPIRALEvery episode results in worseninghealth and damage to vital organs,
such as the heart and kidneys,which decreases the chance
of the patient surviving another episode
‘It felt like I was drowning’
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
SIGNS &SYMPTOMS
URGENTNEED
PREVALENCE& INCIDENCE
12
34
SYMPTOMS
Breathlessness1
Incapacitation2
Fluid build-upWeight gain
34
As an AHF episodeapproaches, patientsexperience: Patients rushed to
the emergency roomfor urgent treatment
3–4%of patients do not survive
the initial episodeZannad F. et al. Heart failure burden and therapy. Europace. 2009;11:v1-v9. Irish Heart Foundation. Living well with heart failure patient booklet http://bit.ly/11FDqR6 Accessed August 2013. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53(7):557-73. Gheorghiade M et al. Rehospitalization for heart failure: problems and perspectives. Journal of the American College of Cardiology. 2013;61(4):391-403. Mosterd A, Hoes, A. Clinical epidemiology of heart failure. Heart. 2007;93:1137-1146. Felker et al. Clinical trial of pharmacological therapies in acute heart failure syndromes. Circulation: Heart Failure. 2010;3:314-325. Weintraub et al. Acute heart failure syndromes. Circulation. 2010;122:1975-1996
ACUTE HEART FAILURE (AHF) EPISODES – A DOWNWARD SPIRALHeart failure is often fatal when patients have one or repeated AHFepisodes
SELECT NUMBERS TO VIEW
DOWNWARD SPIRALEvery episode results in worseninghealth and damage to vital organs,
such as the heart and kidneys,which decreases the chance
of the patient surviving another episode
‘It felt like I was drowning’
MORTALITYRATES
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
SIGNS &SYMPTOMS
URGENTNEED
PREVALENCE& INCIDENCE
12
34
SYMPTOMS
Breathlessness1
Incapacitation2
Fluid build-upWeight gain
34
As an AHF episodeapproaches, patientsexperience: Patients rushed to
the emergency roomfor urgent treatment
3–4%of patients do not survive
the initial episode
20–30%of patients die within
1 year after experiencingan AHF episode
Zannad F. et al. Heart failure burden and therapy. Europace. 2009;11:v1-v9. Irish Heart Foundation. Living well with heart failure patient booklet http://bit.ly/11FDqR6 Accessed August 2013. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53(7):557-73. Gheorghiade M et al. Rehospitalization for heart failure: problems and perspectives. Journal of the American College of Cardiology. 2013;61(4):391-403. Mosterd A, Hoes, A. Clinical epidemiology of heart failure. Heart. 2007;93:1137-1146. Felker et al. Clinical trial of pharmacological therapies in acute heart failure syndromes. Circulation: Heart Failure. 2010;3:314-325. Weintraub et al. Acute heart failure syndromes. Circulation. 2010;122:1975-1996. Harrison’s ‘Principles of Internal Medicine’, Seventeenth Edition pages 1442 - 1455. National heart failure audit: April 2010 – March 2011, NICOR and The British Society for Heart Failure, commissioned by the Healthcare Quality Improvement Partnership (HQIP). O’Connor M et al. Causes of death and rehospitalization in patients hospitalized with worsening heart failure and reduced left ventricular ejection fraction. American Heart Journal. 2010;159(5): 842-849. Hunt S et al. Focused update incorporated into the ACC/AHA 2005. Circulation. 2009;119:e391-e479
Patients with acute heart failure may suffer an increasing numberof episodes as their condition deteriorates, leading to frequent
hospitalization, a downward spiral in health, and a high rate of mortality
SIGNS &SYMPTOMS
ANNUALSTATISTICS COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
MORTALITYRATES
URGENTNEED
MORTALITYFUNCTION AND
QUALITY OF LIFE
Progressive declinein the functionof the heart
Acuteepisode
Harrison’s ‘Principles of Internal Medicine’, Seventeenth Edition pages 1442 - 1455. National heart failure audit: April 2010 – March 2011, NICOR and The British Society for Heart Failure, commissioned by the Healthcare Quality Improvement Partnership (HQIP). O’Connor M et al. Causes of death and rehospitalization in patients hospitalized with worsening heart failure and reduced left ventricular ejection fraction. American Heart Journal. 2010;159(5): 842-849. Hunt S et al. Focused update incorporated into the ACC/AHA 2005. Circulation. 2009;119:e391-e479. Weintraub et al. Acute heart failure syndromes. Circulation. 2010;122:1975-1996. Alla et al. Epidemiology of acute heart failure syndromes. Heart Fail Rev. 2007;12:91–5. Cleland et al. The EuroHeart Failure survey programme – a survey on the quality of care among patients with heart failure in Europe. European Heart Journal. 2003;24:442–636. Gheorghiade et al. Pathophysiologic targets in the early phase of acute heart failure syndromes. American Journal of Cardiology. 2005;96:11G–17G
20 to 30%of patients diewithin 1 year
after experiencingan AHF episodeand 3-4% do not
survive theinitial episode
PREVALENCE& INCIDENCE
MILLIONS OF ACUTE HEART FAILURE (AHF) EPISODESHAPPEN EVERY YEAR
SIGNS &SYMPTOMS
MORTALITYRATES COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
ANNUALSTATISTICS
URGENTNEED
Each year around
3.5 million acute heart failure (AHF)episodes happen in theUS and EU alone; this is
expected to increase furtheras the population ages.
Lined up end to end, the number of ambulances for every AHF patient taken to the hospital in a single year would stretch nearly 21,000 km — almost as long as the Great Wall of China
If everyone in the worldwith heart failure gatheredin one country, it would be
about the population of Australia
21,000 km
Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology. 2009;53(7):557-73
PREVALENCE& INCIDENCE
Answer Answer
HEART FAILURE REPRESENTS A MAJORAND GROWING HEALTH ECONOMIC BURDEN
Acute heart failure is the most common cause ofhospitalization in patients over 65 years
SIGNS &SYMPTOMS
MORTALITYRATES COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
ANNUALSTATISTICS
URGENTNEED
What is the estimatedglobal cost of heart
failure per year?
What percentage of allhealthcare expenditure in
developed countries isthought to be spent
on heart failure?
Answer
What percentage of the cost of heart failure is
due to pharmacological treatment?
PREVALENCE& INCIDENCE
Lloyd-Jones et al. Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation. 2010;121:e46-215. Neumann et al. Heart failure: the commonest reason for hospitalization in Germany – medical and economic perspectives. Dtsch Arztebl Int. 2009;106:269–75. Berry et al. Economics of chronic heart failure. European Journal of Heart Failure. 2001;3:283-291. Stewart et al. The current cost of heart failure to the National Health Service in the UK. European Journal of Heart Failure. 2002;4:361-371. Forman et al. Influence of age on the management of heart failure. American Heart Journal. 2009;157:1010-1017. Healthcare Cost and Utilization Project 2009 http://1.usa.gov/s083eF Accessed August 2013
Answer Answer
HEART FAILURE REPRESENTS A MAJORAND GROWING HEALTH ECONOMIC BURDEN
Acute heart failure is the most common cause ofhospitalization in patients over 65 years
SIGNS &SYMPTOMS
MORTALITYRATES COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
ANNUALSTATISTICS
URGENTNEED
What is the estimatedglobal cost of heart
failure per year?
What percentage of allhealthcare expenditure in
developed countries isthought to be spent
on heart failure?
Answer
What percentage of the cost of heart failure is
due to pharmacological treatment?
PREVALENCE& INCIDENCE
Lloyd-Jones et al. Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation. 2010;121:e46-215. Neumann et al. Heart failure: the commonest reason for hospitalization in Germany – medical and economic perspectives. Dtsch Arztebl Int. 2009;106:269–75. Berry et al. Economics of chronic heart failure. European Journal of Heart Failure. 2001;3:283-291. Stewart et al. The current cost of heart failure to the National Health Service in the UK. European Journal of Heart Failure. 2002;4:361-371. Forman et al. Influence of age on the management of heart failure. American Heart Journal. 2009;157:1010-1017. Healthcare Cost and Utilization Project 2009 http://1.usa.gov/s083eF Accessed August 2013
and growing
Over
$billion45 $
Answer Answer
HEART FAILURE REPRESENTS A MAJORAND GROWING HEALTH ECONOMIC BURDEN
Acute heart failure is the most common cause ofhospitalization in patients over 65 years
SIGNS &SYMPTOMS
MORTALITYRATES COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
ANNUALSTATISTICS
URGENTNEED
What is the estimatedglobal cost of heart
failure per year?
What percentage of allhealthcare expenditure in
developed countries isthought to be spent
on heart failure?
Answer
What percentage of the cost of heart failure is
due to pharmacological treatment?
PREVALENCE& INCIDENCE
of total healthcarebudget in many countries isspent on the management
of heart failure
~–2%
Lloyd-Jones et al. Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation. 2010;121:e46-215. Neumann et al. Heart failure: the commonest reason for hospitalization in Germany – medical and economic perspectives. Dtsch Arztebl Int. 2009;106:269–75. Berry et al. Economics of chronic heart failure. European Journal of Heart Failure. 2001;3:283-291. Stewart et al. The current cost of heart failure to the National Health Service in the UK. European Journal of Heart Failure. 2002;4:361-371. Forman et al. Influence of age on the management of heart failure. American Heart Journal. 2009;157:1010-1017. Healthcare Cost and Utilization Project 2009 http://1.usa.gov/s083eF Accessed August 2013. Dickstein et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008. European Heart Journal. 2008;29;2388–2442
Answer Answer
HEART FAILURE REPRESENTS A MAJORAND GROWING HEALTH ECONOMIC BURDEN
Acute heart failure is the most common cause ofhospitalization in patients over 65 years
SIGNS &SYMPTOMS
MORTALITYRATES COST MYTH
OR FACT TREATMENTCOMMONCAUSES
WHAT ISHEART FAILURE?
ANNUALSTATISTICS
URGENTNEED
What is the estimatedglobal cost of heart
failure per year?
What percentage of allhealthcare expenditure in
developed countries isthought to be spent
on heart failure?
Answer
What percentage of the cost of heart failure is
due to pharmacological treatment?
PREVALENCE& INCIDENCE
<10%
Lloyd-Jones et al. Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation. 2010;121:e46-215. Neumann et al. Heart failure: the commonest reason for hospitalization in Germany – medical and economic perspectives. Dtsch Arztebl Int. 2009;106:269–75. Berry et al. Economics of chronic heart failure. European Journal of Heart Failure. 2001;3:283-291. Stewart et al. The current cost of heart failure to the National Health Service in the UK. European Journal of Heart Failure. 2002;4:361-371. Forman et al. Influence of age on the management of heart failure. American Heart Journal. 2009;157:1010-1017. Healthcare Cost and Utilization Project 2009 http://1.usa.gov/s083eF Accessed August 2013
MYTH OR FACT
SIGNS &SYMPTOMS
MORTALITYRATES COST TREATMENTCOMMON
CAUSESWHAT IS
HEART FAILURE?ANNUAL
STATISTICSMYTH
OR FACTURGENT
NEED
Acute heart failure patientshave a better prognosis
than cancer patients
Myth or Fact ?
Cancerdeaths
Cancerdeaths
Heartfailure
deaths
Heartfailure
deaths
The signs and symptomsof heart failure areeasy to recognise
Myth or Fact ?
Heart failure affectsmostly men
Myth or Fact ?
PREVALENCE& INCIDENCE
MYTH OR FACT
SIGNS &SYMPTOMS
MORTALITYRATES COST TREATMENTCOMMON
CAUSESWHAT IS
HEART FAILURE?ANNUAL
STATISTICSMYTH
OR FACTURGENT
NEED
Acute heart failure patientshave a better prognosis
than cancer patients
Myth or Fact ?
The signs and symptomsof heart failure areeasy to recognise
Myth or Fact ?
Heart failure affectsmostly men
Myth or Fact ?
PREVALENCE& INCIDENCE
Acute heart failure causesmore deaths than some
advanced cancers, includingbreast and bowel cancer
Myth
Heartfailure
deaths
Cancerdeaths
Stewart et al. More ‘malignant’ than cancer? Five-year survival following a first admission for heart failure. European Journal of Heart Failure. 2001;3:315-322
MYTH OR FACT
SIGNS &SYMPTOMS
MORTALITYRATES COST TREATMENTCOMMON
CAUSESWHAT IS
HEART FAILURE?ANNUAL
STATISTICSMYTH
OR FACTURGENT
NEED
Acute heart failure patientshave a better prognosis
than cancer patients
Myth or Fact ?
Cancerdeaths
Cancerdeaths
Heartfailure
deaths
Heartfailure
deaths
The signs and symptomsof heart failure areeasy to recognise
Myth or Fact ?
Heart failure affectsmostly men
Myth or Fact ?
PREVALENCE& INCIDENCE
Despite the incidence, only 3% of the general public
in Europe can identify the signsand symptoms of heart failure
Myth
Remme et al. Public awareness of heart failure in Europe: first results from SHAPE. European Heart Journal. 2005;26:2413-2421
MYTH OR FACT
SIGNS &SYMPTOMS
MORTALITYRATES COST TREATMENTCOMMON
CAUSESWHAT IS
HEART FAILURE?ANNUAL
STATISTICSMYTH
OR FACTURGENT
NEED
Acute heart failure patientshave a better prognosis
than cancer patients
Myth or Fact ?
Cancerdeaths
Cancerdeaths
Heartfailure
deaths
Heartfailure
deaths
The signs and symptomsof heart failure areeasy to recognise
Myth or Fact ?
Heart failure affectsmostly men
Myth or Fact ?
PREVALENCE& INCIDENCE
There is a widespreadmisconception that heart failure
is a man's disease. But heartfailure is also a devastatinghealth problem for women
Myth
Cleveland clinic: Heart Failure & women http://bit.ly/qw4pEv Accessed August 2013
NO TREATMENT BREAKTHROUGHS IN 20 YEARSDespite significant progress in treating other heart conditions, there have been no major
developments in treatment for patients with acute heart failure for two decades
Commonly used medicines for AHF treat only immediate symptoms and have not beenproven to have an impact on longer-term outcomes
SIGNS &SYMPTOMS
MORTALITYRATES COSTCOMMON
CAUSESWHAT IS
HEART FAILURE?ANNUAL
STATISTICSMYTH
OR FACT TREATMENT URGENTNEED
DISCOVER CURRENTLY AVAILABLE TREATMENT OPTIONS
TREATMENTGOALS
CURRENT TREATMENTOPTIONS
Option Option Option
Cowie M et al. Acute heart failure – a call to action. British Journal of Cardiology. 2013;20(suppl 2):S1-S11. Hunt S et al. Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. Circulation. 2009;119:e391-e479. McMurray et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012. European Heart Journal. 2012;33:1787-1847. Gheorghiade et al. Acute Heart Failure Syndromes: Current State and Framework for Future Research. Circulation. 2005;112:3958-3968
PREVALENCE& INCIDENCE
NO TREATMENT BREAKTHROUGHS IN 20 YEARSDespite significant progress in treating other heart conditions, there have been no major
developments in treatment for patients with acute heart failure for two decades
Commonly used medicines for AHF treat only immediate symptoms and have not beenproven to have an impact on longer-term outcomes
SIGNS &SYMPTOMS
MORTALITYRATES COSTCOMMON
CAUSESWHAT IS
HEART FAILURE?ANNUAL
STATISTICSMYTH
OR FACT TREATMENT URGENTNEED
DISCOVER CURRENTLY AVAILABLE TREATMENT OPTIONS
TREATMENTGOALS
CURRENT TREATMENTOPTIONS
Option Option Option
Cowie M et al. Acute heart failure – a call to action. British Journal of Cardiology. 2013;20(suppl 2):S1-S11. Hunt S et al. Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. Circulation. 2009;119:e391-e479. McMurray et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012. European Heart Journal. 2012;33:1787-1847. Gheorghiade et al. Acute Heart Failure Syndromes: Current State and Framework for Future Research. Circulation. 2005;112:3958-3968
PREVALENCE& INCIDENCE
IMMEDIATE:Treat symptoms
Help patients breatheReduce fluid build-up
DiureticsVasodilators
Oxygen therapyInotropes
NO TREATMENT BREAKTHROUGHS IN 20 YEARSDespite significant progress in treating other heart conditions, there have been no major
developments in treatment for patients with acute heart failure for two decades
Commonly used medicines for AHF treat only immediate symptoms and have not beenproven to have an impact on longer-term outcomes
SIGNS &SYMPTOMS
MORTALITYRATES COSTCOMMON
CAUSESWHAT IS
HEART FAILURE?ANNUAL
STATISTICSMYTH
OR FACT TREATMENT URGENTNEED
DISCOVER CURRENTLY AVAILABLE TREATMENT OPTIONS
TREATMENTGOALS
CURRENT TREATMENTOPTIONS
Option Option Option
Cowie M et al. Acute heart failure – a call to action. British Journal of Cardiology. 2013;20(suppl 2):S1-S11. Hunt S et al. Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. Circulation. 2009;119:e391-e479. McMurray et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012. European Heart Journal. 2012;33:1787-1847. Gheorghiade et al. Acute Heart Failure Syndromes: Current State and Framework for Future Research. Circulation. 2005;112:3958-3968
PREVALENCE& INCIDENCE
Limit cardiac andrenal damage
No therapiescurrentlyavailable
NO TREATMENT BREAKTHROUGHS IN 20 YEARSDespite significant progress in treating other heart conditions, there have been no major
developments in treatment for patients with acute heart failure for two decades
Commonly used medicines for AHF treat only immediate symptoms and have not beenproven to have an impact on longer-term outcomes
SIGNS &SYMPTOMS
MORTALITYRATES COSTCOMMON
CAUSESWHAT IS
HEART FAILURE?ANNUAL
STATISTICSMYTH
OR FACT TREATMENT URGENTNEED
DISCOVER CURRENTLY AVAILABLE TREATMENT OPTIONS
TREATMENTGOALS
CURRENT TREATMENTOPTIONS
Option Option Option
Cowie M et al. Acute heart failure – a call to action. British Journal of Cardiology. 2013;20(suppl 2):S1-S11. Hunt S et al. Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. Circulation. 2009;119:e391-e479. McMurray et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012. European Heart Journal. 2012;33:1787-1847. Gheorghiade et al. Acute Heart Failure Syndromes: Current State and Framework for Future Research. Circulation. 2005;112:3958-3968
PREVALENCE& INCIDENCE
LONG TERM:Improve survival and
organ protection
No therapiescurrentlyavailable
MORE NEEDS TO BE DONEThere is an urgent need for new treatments to help relieve symptoms
and increase patients’ life expectancy by protecting vitalorgans against life-threatening damage during an AHF episode
SIGNS &SYMPTOMS
MORTALITYRATES COST URGENT
NEEDCOMMONCAUSES
WHAT ISHEART FAILURE?
ANNUALSTATISTICS
MYTHOR FACT TREATMENT
RELIEVESYMPTOMSNEW
TREATMENTS
PROTECTORGANS
INCREASE LIFEEXPECTANCY
PREVALENCE& INCIDENCE