hair transplant surgery for hair disorders...• philpott mp, kealey t. hair follicles engage in...

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Hair Transplant Surgery for Hair Disorders Dr Bessam Farjo Manchester & London, UK Diplomate, American Board of Hair Restoration Surgery Past President, International Society of Hair Restoration Surgery Past President, British Association of Hair Restoration Surgery Fellow, Institute of Trichologists

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Page 1: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Hair Transplant Surgery for Hair Disorders

Dr Bessam FarjoManchester & London, UK

Diplomate, American Board of Hair Restoration SurgeryPast President, International Society of Hair Restoration Surgery

Past President, British Association of Hair Restoration SurgeryFellow, Institute of Trichologists

Page 2: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Hair Transplant Surgery Disease Indications

YES

• Male-Pattern

• Female-Pattern

• Dormant LPP

• Secondary Cicatricial

• Traction Alopecia

• Triangular Alopecia

NO

• Telogen Effluvium

• Anagen Effluvium

• Alopecia Areata & Variants

• Active Primary Cicatricial

• Follicultis Decalvans

• Lupus Erythematosis

• ? Any stage FFA ?

• Trichotillomania

Page 3: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Patient Selection

Page 4: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Examination: Young, likely further loss

Page 5: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Excellent

• Reasonable expectations

• Good to Excellent hair quality and donor density

• Low potential for further hair loss

• Good scalp laxity (FUT)

• Motivated to use medical therapy

• Females: specific area of hair loss (vs generalized)

Page 6: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol
Page 7: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Frontal Fibrosing Alopecia

Page 8: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Scarring Alopecia (Female)

SCARRING ALOPECIA

Page 9: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

LPP/FFA Koebner?

Page 10: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Hairline DesignTrichion (central & usually lowest point)

Page 11: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Peaks & troughs

Page 12: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Donor Hair Assessment: Objective

• Hair loss progresses throughout one’s life, and

• as such the permanent donor hair has to be assessed in a logical and scientific manner in order to ‘future proof’ the surgery.

Page 13: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Factors to consider when making recipient sites

• Recipient Sites determine the individual placement of the grafts

• Sites determine the overall aesthetic result of the hair transplant

o Direction

o Angle

o Depth

o Orientation

o Geometry

o Density

Page 14: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Site direction

Page 15: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Recipient Site density

• Dense packing - probably 40 grafts/cm2 or above

• Studies showing undoubted significant reduced yield beyond 50 grafts

Page 16: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Incision density

4500 GRAFTS – 45 GRAFTS/CM2 AVERAGE

Page 17: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

2 Methods of Donor Harvesting

• Follicular Unit Extraction (FUE)

– Manual or Mechanised

– Automated Robot-Assisted

• Strip Technique (FUT)

Page 18: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Follicular Unit Excision (FUE)

• Method of harvesting the donor

• Use 0.7 – 1.2 mm manual or automated punches to

extract individual follicular unit grafts

• Usually requires a full shave of the donor area

• Limited shaving or clipping for smaller numbers

Page 19: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Skill in reducing transection

Page 20: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Post operatively

Page 21: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Motorised (Non-Robotic) FUE

Page 22: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Motorised (Non-Robotic) FUE

Page 23: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

6-8x magnification ideal

Page 24: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Needle Mechanism and Video Camera

System

Cart

Robotic Arm

The ARTAS® Robotic System

Monitor Screen

Page 25: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

User Interface During Harvesting

Page 26: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Strip FUT Harvesting Method

• Narrow, but long strip or skin graft excised from a dense central area– Should be able to completely

cover with hair

• Strip is then microscopically dissected into individual grafts

• Usually needs larger set up and skilled technical staff

Page 27: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol
Page 28: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Typical Megasession Donor Site

Page 29: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Donor Scar with Trichophytic Closure

Page 30: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Available Graft Storage Solutions

IV solutions used for storage– Normal Saline

– Lactated Ringers

– Plasma-Lyte A (contains acetate and gluconate) ph 7.4

Advanced tissue storage solutions– Hypothermasol (hypothermic) ph 7.6

– Custodial

– Marshall’s

– 2-8CELLsius

Culture media (not licensed for clinical use)

– DMEM (Dulbecco's Modified Eagle's Medium)

– William’s E media

Page 31: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

References

• Parsley W, Perez-Meza D. Review of factors affecting the growth and survival of follicular grafts. J Cutan Aesthet Surg. 2010;3(2):69-75

• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol. 1991;96(6):875-9

• Mathew A. A review of cellular biopreservation considerations during hair transplantation. Hair transplant forum int. 2013;23:1

• Krugluger W, Moser K, Moser C, Laciak K, Hugeneck J. Enhancement of in vitro hair shaft elongation in follicles stored in buffers that prevent follicle cell apoptosis. Dermatol Surg. 2004;30(1):1-5

• Wise ES, Hocking KM, Eagle S, Absi T, Komalavilas P, Cheung-Flynn J, Brophy CM. Preservation solution impacts physiological function and cellular viability of human saphenous vein graft. Surgery, 2015;158(2):537-46

Page 32: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Placing with Implanters

Page 33: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Female Pattern, Surgical Issues: Limitation of donor

Usually 1200 – 2000 grafts per op

• The parietal area is commonly thinning as well

• The scalp is generally tighter than men

• The suitable occipital area is narrow and low

Page 34: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Before After

EYEBROW AUGMENTATION inUlerythema Oopheregenes

Page 35: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Burn Alopecia

Before After

Page 36: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Beard & Moustache Burns

Page 37: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Temporal Triangular Alopecia

Page 38: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Close up before and after

Page 39: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Traction Alopecia

Page 40: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

POST RADIOTHERAPY

Page 41: Hair Transplant Surgery for Hair Disorders...• Philpott MP, Kealey T. Hair Follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. J Invest Dermatol

Thank you!

[email protected]

www.farjo.com