h3abionet newsletter july 2016 issue 16 nm edits · 2019. 3. 13. · page | 1 h3abionet monthly...
TRANSCRIPT
P a g e |1H3ABioNetMonthlyNew
sletterIssue16:July2016
ThisnewsletterdescribestheH3ABioNetactivitiesfromJanuarytoJune2016.The
firsthalfof this yearhas seen thesuccessful completionofanumberof training
workshops and the Education and Training working is busy working on the
organizationofseveralnewworkshopswhichwilltakeplaceoverthesecondhalf
of the year. This issue includes an article describing the experiences of a trainer
from one of the workshops which H3ABioNet provided support for. In other
exciting trainingnews,our first IntroductiontoBioinformaticsCoursehasstarted
andisbeingbroadcastto19classroomsaroundAfrica.Wewillkeepyouupdated
onitsprogress!
The other working groups are also working hard towards achieving their
milestonesandsomeoftheiractivitiesaredescribedbelowintheirworkinggroup
reports. The research working group established a Research proposals sub-
committeetoprovidesupportforgrantproposalsthroughpeerreview.Ihopethe
studentsandresearcherswilltakeadvantageofthis initiativeto improvefunding
and other proposals before they get submitted. The working group has also
successfullyrunamonthlywebinarserieswhichhasseensomeexcellentresearch
talkspresentedbybothjuniorandseniorscientists.
At H3ABioNet Central we submitted the H3ABioNet annual report to the NIH,
which include requestedbudgets for year 5, our final year of the grant!We are
nowpreparing for thenext phase,and templates havebeen sentout toexisting
andpotentialnewnodestocompleteiftheyareinterestedinparticipatinginthe
newproposalforanH3AfricaInformaticsNetwork.
Iinviteyounowtocontinuereadingtofindoutmoreaboutouractivitiesoverthelastfewmonths.
Prof.NickyMulder
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Anumberof trainingworkshopshavebeenplannedand runduring the firsthalfof
2016 with various levels of involvement from H3ABioNet. The first was a Whole
Genome and RNA Sequencing workshop hosted by the University of Khartoum,
Sudan inMarch 2016. The training was conducted as a pre-conference workshop
during the University of Khartoum’s Postgraduate Conference. The workshop was
held over five days and covered the practical analysis of whole-exome and RNA
sequencing data. Although H3ABioNet did not directly fund the workshop, several
H3ABioNet students were given travel fellowships to attend. You may read more
aboutthisworkshopinafeaturearticleincludedinthisnewsletter.
Aworkshop, focused on the Bioinformatics Analysis and Annotation of Variants in
NGSdata,washeldasasatelliteworkshoptothePharmacogenomicsandPrecision
MedicineConference,inApril2016atUniversityofCapeTown(UCT).Theworkshop
wasaimedatgenetics,genomicsandbioinformaticsresearchersinterestedintheuse
of genomic data for personalizing treatment. It included a combination of lectures
andhands-on practical exercises covering topics such asNGS theory (anoverview)
andannotationofvariants,includingfunctionalanalysisandimplications.H3ABioNet
provided travel fellowships to 6 African students to attend the workshop and
contributedtoteachingandsettingupofinfrastructurefortheworkshop.
TheH3AfricaNicolproject,incollaborationwiththeJ.CraigVenterInstitute,USA,ran
a practical workshop on microbiome analysis at UCT in April 2016. H3ABioNet
provided technicalandadministrativesupportandcontributed to theteaching.The
workshopprovidedabackgroundtomicrobiomestudiesandcoveredtopicssuchas
sample preparation, sequencing, run interpretation, pipeline processing for
taxonomic classification and post-processing analysis. The workshop was designed
for participantswho already have basic bioinformatics skills andwhomay already
havebeeninvolvedinmicrobiomework.
TheH3ABioNetEducationandTrainingworkinggroup(E&TWG),inconjunctionwith
theH3ABioNetInfrastructureworkinggroup,heldadatasupportworkshoppriorto
the8thH3Africaconsortiummeeting inSenegal inMay2016.H3ABioNet flewin17
H3AfricaDataSupportworkinggroupmemberstoattend.Thisinteractiveworkshop
provided an overview of data management, analysis and submission for H3Africa
projects. ItalsoprovidedanopportunityforDataSupportWorkingGroupmembers
who represent the H3Africa projects, to engage with H3ABioNet and discuss their
needs.
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Tocomplementourformaltrainingendeavours,anumberofinternshavealsobeen
placedinordertogainsomeone-on-onetrainingatourpartnernodesinH3ABioNet.
Mr Shaun Aron from the University of the Witwatersrand H3ABioNet node was
awarded an internship at Harvard, wherehe spent 3monthsworkingwith various
experts inpopulationgenetics. The latest internships includeMsAzzaAhmed,who
hasbeenawardedaninternshipatourUniversityofIllinoisH3ABioNetnode,where
she will learn about high performance computing for whole exome and RNA
sequence data. Trust Odia and Falola Oluwadamilare from Covenant University in
Nigeria have been placed at the Institute Pasteur node in Tunisia to work on
modellingofhost-pathogeninteractions.
The E&T WG is also excited to announce that the online Introduction to
Bioinformaticscoursewassuccessfullylaunchedonthe13thJuly2016andiscurrently
underway. An immense amount of planning and preparation has gone into
developingthecourseandweareexcitedtohaveover350participantsregisteredfor
thecourseacross19classroomsin11Africancountries!Wehavejustcompletedthe
firsttwo-weekmoduleforthecourse(DatabasesandResources)andhavereceived
somegreatpositivefeedbackfromtheclassroomsthusfar.Besuretocheckoutthe
course webpage that contains information on all the classrooms as well as the
recordedcoursematerial(lecturerecordings,slidedecksandpracticalassignments)
astheybecomeavailable.http://training.h3abionet.org/IBT_2016/?page_id=130.
IBTwebsitehomepage.Lecturevideos,slidesandassignmentsareopenaccess
ShaunAronandNickyMulder
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TheInfrastructureworkinggroup(ISWG)hasbeenbusyinthefirstsixmonthsof
2016.
• WehelpedrunaverysuccessfulDataSupportWorkshop,inconjunctionwiththeE&TWG,atthe8thH3AfricaConsortiumMeetinginDakar,Senegal.Thisbroughttogetherresearchgroups,representativesofthebiorepositories,andotherkeystakeholderstodiscussandplanhowdata,generatedbytheresearchgroups,willbeprocessedandmoved.Afterhearingfromparticipantsontheirgoals,wehadsessionson:laboratoryinformationmanagementsystems;dataharmonisation;overviewofkeypipelinesandanalysis;dataprocessing,storage,transferandsecurityoptions;anddrawingupadatamanagementplan.
• TheH3AfricaParticipantsRecruitmentDatabasewentintooperation.AttherequestofthefunderswedevelopedadatabasesystemtoallowH3Africaprojectstoreportonprogressinrecruitmentofparticipantsandcollectionofdata.ImplementedusingREDCap,thesystemwasdevelopedinashortperiodoftimeandhasreceivedgoodfeedbackfromall.Manypeoplewereinvolvedinthis,butparticularcreditgoestoMamanaMbiyavanga.
• TheCloudComputingTaskforceheldseveralon-linemeetings,andstartedacollaborationwithVictorJongeneel’sgroupattheUniversityofIllinoistoworkonprojectsofcommoninterest.WeareplanningaCloudHackathonforAugust2016todevelopportablecomputationalpipelinesofrelevanceforH3Africaandtodevelopskillsonthecontinent.
• ManymembersoftheISWGhavebeenverybusywiththeH3AfricaCustomChipdesignproject.Using300genomesgeneratedbyH3Africaprojectsaswellasotherdatasets,H3ABioNetisworkingwithpartnerstodevelopacustomchipfortheGWASprojectsbeingdoneinH3Africa.Thishasrequiredhugecross-continentaldatatransfers(over100TB)andlotsofcomputation.
• Wearestillbusywithanumberoflongtermprojects,including:rolloutofNetmapandGlobusOnlineendpointsformanagingandmonitoringdatatransfers;deployingandupgradingeBiokits;andupdatingsystemsadministrationdocumentation.
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Afteraperiodofrelativelylittlework,theDataManagementTaskforceisstartingto
gearupfortheexpecteddelugeofdatafromtheH3AfricaProjects.Thiswillbea
majorareaofworkforthenext6months.RolloutoftheGlobusOnlineandnetmap
endpointswillcontinue,too.
DataSupportworkshopat8thH3AfricaconsortiummeetinginDakar,Senegal
SureshMaslamoneyScottHazelhurst
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Since January 2016, a bioinformatics themehas been chosen for each researchseminar run by the Research Working Group (RSWG). For each session, twospeakers working in the field are invited to give a 20-minute presentation,followed by 10-15 minutes for interactions with participants, questions andanswers. Topics covered so far are: GWAS and Population Genetics;Metagenomics; Big Data; NGS; and planning ones career within the field ofbioinformatics.
TheH3ABioNetResearchProposalsSub-committeewasestablished.ThechairoftheRSWGcompliedadraftforgeneralproposalguidelines,whichwascirculatedamongthemembersoftheworkinggroupaswellasotherinterestedmembersofthe H3ABioNet network. Somemembers of this sub-committee expressed theirwillingnesstoreviewnodes'proposalsaswellasgraduatestudents'proposals.
AsecondMozillaStudyGroupwaslaunchedinKhartoum,SudaninMarch2016asafollowupfor theNGStrainingworkshopthattookplacethere.AzzaAhmed isleadingthestudygroup,whichmeetseveryMonday.Duringeachmeeting, twomembers of the group, on a rotation basis, present and summarize a chapterwithinaselectedbioinformaticsbookorarticle.This isfollowedbydiscussionofthe presented material. We are aiming to launch other study groups at thedifferentH3ABioNetnodes.
H3ABioNetisorganizingajointhackathonwiththeIBMResearchAfricateam.Themain objective of this hackathon is to analyse transcriptional data sets from arangeofMalaria parasite isolatesexposed toartemisinin inculture,whichhavebeen generated by University Notre Dame (US). This data needs to be pre-processed andprepared for anopen challenge thatwill be launched under theDREAMChallengesinitiativewithinthenext2years.ThehackathonwillbeheldinJohannesburg, South Africa from 5th to 10th September 2016. For furtherinformation, kindly refer to the hackathon call available at this link:http://h3abionet.org/h3abionet-ibm-research-africa-hackathon-malaria-drug-resistance-2016
SocialmediachannelsliketwitterandFacebookhavealsobeenusedtoadvertise
for the H3ABioNet Researchworking group seminars to promote the seminars
andattractmoreattendees.
AmelGhouilaFaisalFadlelmola
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Overview
Thisperiod (January– July2016)camerighton theheelsof the fourthconsortium
Annual general meeting in November 2015, and so began with lots of promise.
StrategyfortheYear4activitieswaspresentedatthegeneralmeetingandwastobe
quicklyadoptedandimplemented.Highonthelistwere:establishmentofthelong-
overduenodeliaisonscheme,theHelpdeskmanagementcommittee,newtoolsfor
outreach among these slide decks, flyers, brochures, the group article, and an
improvedwebsite-allgearedtowardsengagingawidersetofaudiences.
Progresssofar
Ofthelistedactivitiesabove,wehavemadesomeprogressonthefollowing:
• Membertermsofreference(TOR)-thesehavebeenupdatedandrevised.
• Work group reconstitution - we have registered dwindling meetingparticipation from members. We are currently revisiting working groupcomposition,callingfornewvolunteers,re-examiningcompileddeliverablesandlayingoutnewstrategysforfutureoperations.
• Helpdesk management committee - advanced work plans are in place forthisactivity.
• Outreach-wearegearingtostartonthisinearnest.
• Helpdeskarticle-hasbeenstartedonbut isyet tobe finalized,so there isstill roomforadditional contribution andauthorship. Please get in touch ifinterested.
Challengesandwayforward
• The dwindling activity participation mentioned above has greatly slowed
down the pace of our group activities. In view of this we are re-branding,
expandingmembershiptoincludevariouscategories,andarefocusingmore
ontheoutreachaspectsofourcompileddeliverables.Forthisweshallneed
adiversesetof skill setsandwesee lotsofopportunities forcontribution.
We are also contemplating the launch of amonthly group journal club to
draw more people. We are calling for renewed commitments from all
volunteers, as success depends on collective participation in our coming
groupactivities.
JonathanKayondoPandamSalifu
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During the initialH3ABioNetGeneralAssembly in2012, theNodeManagersdecided
that thenetwork should developand implementaNodeAssessmentExercise (NAE).
TheprimarygoalfortheNAEwastogiveindividualNodestheopportunitytoprove,in
an objective fashion, that they had reached the level of technical competence that
couldbeexpectedfromgroupsthatwouldprovidedataanalysis servicestoH3Africa
researchprojects. It isoneof themajor goalsof theH3ABioNetnetwork to develop
technical skills and infrastructure on the African Continent to a level where African
scientistsnolongerdependoncolleaguesinEurope,AsiaorNorthAmericatoanalyse
thegenomicdatageneratedbytheirresearchprojects.
ANodeAssessmentTaskForce(NATF)wasassembledaftertheGeneralAssembly,and
taskedwith developing a framework for the organisation of the NAE aswell as the
materials for two specific exercises driven by the needs of the H3Africa research
projects:thecallingofgenomicvariantsfromhigh-throughputgenomesequencedata,
and the processing of chip-based genotyping data followed by genome-wide
associationstudies(GWAS).TheNATFproducedanAssessmentProtocoloutliningthe
procedures used to administer the NAE, including an independent evaluation by
expertsexternal toH3ABioNet. Italsoproduced thematerials for the first twoNAE:
standardoperatingprocedures(SOP)fortheanalysis,trainingdatasetstohelpnodes
prepare for taking the NAE, and personalized test datasets used during the actual
assessment.TheUniversityofCapeTownNodetooktheleadershipfortheGWASNAE,
while the University of Illinois worked on the variant calling NAE. All the necessary
materialswerereadybyend2013.
During the 2013 General Assembly, several nodes expressed the desire to have
additional NAE available to them, to test analysis skills that may be more widely
shared.Asaresult,theNATFproducedtwomoreNAE,fortheanalysisofmicrobiomes
fromthehigh-throughputsequencingof16SrDNAamplicons,andforgeneexpression
analysis from RNA-seq datasets. The necessary materials were prepared in a
collaborationbetween theUCT and Illinois nodes, andhavebeen available fromthe
fallof2014.
The first H3ABioNet node to actually take the plunge was the Wits node in
Johannesburg,whosubmittedtotheNAEinthesummerof2014.TheWitsnodetook
advantageofanH3ABioNetGWAScourseandofthepresenceofanintern fromthe
BotswanaNodetoassembleananalysisteamandashadowteam,whoindependently
analysed the test data.The report theysubmittedwas reviewedvery positively, and
theywereaccreditedwithflyingcolours.Ittookoverayearbeforethenexttwonodes
declaredthemselvesreadyinthefallof2015:theUCTnodeforthevariantcallingNAE,
and theCUBREnode inNigeria for theGWASNAE.Again, bothnodes did verywell,
andwereaccreditedasaresult. It isveryencouragingtoseethatallnodesthattook
theNAEperformedextremelywellintheviewofourexternalexperts.
Itshouldbenoted,however,thatH3ABioNetincludes32differentnodes,andthatso
faronly threehave takenoneof theNAE,andnonehave takenmore thanone.The
H3ABioNetleadershiphasmadeitapriorityforallparticipatingnodestoconcentrate
ontrainingtheirstaff,throughcoursesandinternships,togetreadyandtaketheNAE
beforetheendofthecurrentgrant in2017.Wesincerelyhopethatmorenodeswill
provetheircommitmenttoactuallydeveloptheirtechnicalcapacityandtoparticipate
intheNAEwithinthenextyear. VictorJogeneel
ProgressintheH3ABioNetnodeassessmentexercise
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InMarch 2016 I travelled to Sudan to help run aweeklongwhole exomeandRNAsequencing data analysis course at the University of Khartoum. The course wasattendedby25students,mostlyfromtheUniversityofKhartoumwithawiderangeof backgrounds, including researchers from medicine, veterinary and chemistrydepartments.
ThegroupinfrontoftheUniversityLibrary
CourseDesign
Iwastaskedwithcoveringthewholeexomesequencing(WES)process.Istartedwithan introduction to sequencing technologies, different sequencing approaches, andthechallengesposedbyeachapproach.OverthenextfewdaysIcoveredalignment,variantcallingandannotation,thebioinformaticprocessesrequiredtoturn therawsequencing data into a list of variants and how to analyse and interpret thesevariants.Themorningsconsistedoftalksprovidingabackgroundtotheconceptsandtools,whichwerethenappliedinthepracticalsessionafterlunch.
Thefirstpracticalsessiontookstudentsfromtherawdata(BAMfile)throughtoalistof variants (vcf file), covering quality control and applying different filters. In thesecondsessionstudentstookarealdiagnosticcase,usingthepatient'sphenotypetodesign a gene panel, annotate variants and apply filters and bioinformatic tools toidentifythecausativevariants.
Thecourseranverysmoothly
The course and practical sessions ran very smoothlywith students very interactiveandopen,askinglotsofquestionsanddemonstratingunderstandingofthematerialpresented. Under the leadership of Prof. Faisal Fadlelmola the University hasdeveloped a very good computer infrastructure, ideally suited to running such acourse,with20workstationsrunningBioLinuxandacluster,allofwhichare inverysafehandswithAzzaAhmed,thegroup’ssystemadministrator.
Iwould also like to thankRehabAhmedandAzza (again!) for their help answeringquestionsandtroubleshootingthroughoutthepracticals.
WholeexomeandRNAseq
analysiscourse,Khartoum
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Thecomputersuiteiswellsetupforrunningsuchacourse
Coursephotoinclassroom
ExperienceofSudan
I didn’t know what to expect from Khartoum, however I was very pleasantlysurprised.EveryoneImetwasveryfriendlyandhospitable,apointdemonstratedbynearlyhalf thecourseactingasexpertguides forusonatourofKhartoumthedayafterthecoursehadfinished.OneofthestudentskindlypresenteduswithapaintingofanAlzeer,atraditionalpottostorewaterintheAlhoush(thecommunalcourtyardofafamilyhome)shehadpaintedherself.
I felt very safe travelling around the city and despite the city not being a touristhotspot the hotel was very comfortable and we ate very well at a range ofrestaurants!One restaurant even treatedus toaperformance fromoneof finalists(?)fromSudanesePopIdol!
SomethingswereasIexpected-itwashot!Mostdayswereabove40oC(apparently
reaching47oConeday!)withtheoddsandstorm.LuckilythePCroomhadfansandAC! It was interesting to see the PC’s being wrapped up each evening and howdespitethistheywerestillcoveredbysandanddustthefollowingmorning!
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The(?)finalistfrompopidolperformingatarestuarant
TheUniversitylibraryatnight
Thanks
I would like to thank H3ABioNet and the Mozilla Foundation for funding withoutwhich the course would not have been possible and Jelena and Risha for theintroductionsandencouragement!
I’dalsoliketothankFaisalformakingusfeelsowelcomeandhostingusthroughouttheweekandtheUniversityofKhartoumwhowereveryhelpful,makingtheVisaandimmigrationprocessesverysmooth.
ThisarticlecomprisesexcerptsfromanarticlebyAledJones
Originalarticleavailableathttp://trendinafrica.org/wp-content/uploads/2016/04/Sudan-school.pdf
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Recently,SusanSzuchwroteanewspiecefortheNationalCenterforSupercomputing
Applications (NCSA) newspage, in which she described the H3Africa African chip
design project and the invovlement of the NCSA Blue Waters team in making it
possible“todiscovergenomicvariantsinover300deeplysequencedhumansamples
tohelpconstructagenotypingchipspecificforAfricanpopulations”.Asmanyofyou
areaware,theH3AfricaGenomeAnalysisWorkingGrouppartneredwithH3ABioNet
andtheWellcomeTrustSangerInstitutetodesignandconstructthischip,whichwill
be used as a tool for rapid and inexpensive genotyping of individuals in order to
identifygenomicbasesofdisease,specificallyinAfricanpopulations.Duetothelarge
amountsofdata,thisprojectrequiredaveryfastcomputer-wherebettertogothan
NCSA’sBlueWater;thefastestsupercomputeronauniversitycampus.
SzuchnotestheeffortoftheBlueWatersteamasbeinginstrumentaltothesuccess
of the project, in which Professor NicolaMulder’s team at the University of Cape
Town (UCT), in partnership with Dr Manj Sandhu’s team at the Wellcome Trust
Sanger Institute, developed the computational workflow for extracting genomic
variants, and in which the High Performance Biological Computing node (HPCBio)
helpedinitiatetheworkflowonBlueWaters.
Inthearticle,SzuchquotedDr.LiudmilaMainzer,seniorresearchscientistwithNSCA
andtheHPCBiogroup, insayingthat"withouttheir[BlueWaters’] involvementand
professionalism, this work would have been very difficult to complete. For our
project, the Blue Waters team was as important as the compute, storage and
networkingresources."
Thearticlealsodescribeshowtheprojectwasamutuallybeneficialoneandthatthe
NSCA Blue Waters team discovered new tools for data transfer through
troubleshooting problems in conjunction with the H3ABioNet team of
bioinformaticians.Theimportanceofthisprojectintermsofsocialimpactandreach
wasalsonoted.
KimGurwitz
Theoriginalfullarticle,writtenbySusanSzuch,isavailableat
http://www.ncsa.illinois.edu/news/story/supercomputer_changing_genetic_medic
ine_in_africa
SupercomputerchangingGeneticmedicine
inAfrica
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Congratulations to Gerrit Botha and Liudmila Sergeevna Mainzer who recently
provided oral presentations on the bioinformatics data processing of the H3Africa
GenotypingChipandVariantcallingapproachesontheBlueWatersSupercomputer
at the 4th Annual NCSA Blue Waters Symposium
(https://bluewaters.ncsa.illinois.edu/bw-sym-2016)
Gerrit Botha also received theprize for themostdata transfersconductedonBlue
Waters.
Congratulations to two Consortium students (Olivier Sheik Amamuddy and Phillip
Magambo), who completed one-year Bioinformatics MSc programmes in the
ResearchUnit in BioinformaticsatRhodesUniversity in 2015andstarted their PhD
degreesatRUBithisyear.OlivierisfromMauritiusandamemberofProfYasminaJ.
Fakim’sgroupaspartofH3ABioNet,andPhillipisfromUgandaandamemberofProf
EnockMatovu’sgroupaspartofTrypanoGEN.
Congratulations toRUBimembers PhillipMagamboandDavidBrownwhoreceived
best poster and best oral presentation, respectively, at the national SASBMB
conferenceinJuly2016withintheBioinformaticsandOmicstrack.PhillipMagambo
presented his MSc work on a drug discovery project against Human African
Trypanosomiasis (sleeping sickness). David Brown presented his work on “Human
GenomeMutation Analysis Portal –HUMA”which is beingdesigned as part of the
H3ABioNetprojecttohosthumanmutationinformationandanalysenonsynonymous
mutationsattheproteinlevel.
CongratulationstoJaquilineMugofromcentralnode,whowasawardedascholarship
tovisitourSABmemberMarkMcCarthy’s lab inOxfordandtoEmileChimusa,who
has taken up a Senior Lectureship in the Division of Human Genetics at UCT.
CongratulationstoNicolaMulder,whoco-authoredaSciencepaperwiththeGlobal
Alliance for Genomics and Health:
http://www.ncbi.nlm.nih.gov/pubmed/27284183
RUBimembers,RowanHatherley,DavidBrown,MichaelGlenisterandOzlemTastan
Bishop,havecompleted the firstphaseof thehomologymodellingpipeline,PRIMO
(PRotein Interactive Modelling pipeline), and it is available for the use of the
Consortiummembersathttps://primo.rubi.ru.ac.za/.PRIMOisforproteinmonomer
modelling,andallowsuserstomodel ligandsandions incomplexwiththeirprotein
targets.Itsuser-friendlyinterfacemakesiteasytouseandifnecessarytochangethe
modellingparameters.
Anyannouncementsforthenexteditionofthenewslettermaybesendto
[email protected]@uct.ac.za
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August22ndtoAugust26th2016;H3ABioNetCloudcomputinghackathon,Unviersity
ofPretoria,SouthAfrica(http://www.h3abionet.org/17-h3abionet-
courses/h3abionet-courses-upcoming/266-h3abionet-cloud-computing-hackathon)
September5thtoSeptember10th2016;H3ABioNet/IBMResearchAfricaHackathon
onMalariaDrugResistanceforaDREAMchallenge,Johannesburg,SouthAfrica
(http://www.h3abionet.org/h3abionet-ibm-research-africa-hackathon-malaria-drug-
resistance-2016)
September20thtoSeptember23rd2016;Joint2016conferenceoftheSouthAfrican
SocietiesforBioinformaticsandSouthAfricanGeneticsSociety,DurbanSouthAfrica.
**Earlyregistrationdeadline15thofAugust2016(http://www.sasbi-sags.co.za/)
October3rdtoOctober14th2016:INDAHands-onNGS-Statisticscourse,Dakar,
Senegal.**ApplicationscloseonAugustthe15th2016
(http://www.h3abionet.org/component/content/article/17-h3abionet-
courses/h3abionet-courses-upcoming/269-inda-hands-on-ngs-statistics-course)
October27thtoOctober31st2016:NinthH3Africaconsortiummeeting,Mauritius(http://h3africa.org/events/9-news/284-9th-meeting-of-the-h3africa-consortium-2)
November6thtoNovember10th2016;NinthAnnualRECOMB/ISCBConferenceonRegulatory&SystemsGenomics,withDREAMChallenges&CytoscapeWorkshop,Phoenix,Arizona,USA(https://www.iscb.org/recomb-regsysgen2016)
November21sttoNovember23rd2016;ThefourthInternationalSocietyforComputationalBiologyLatinAmericaBioinformaticsConference(ISCB-LA),jointlyorganizedwithA2B2C,willtakeplaceinBuenosAires,Argentina(https://www.iscb.org/iscb-latinamerica2016)
ImportantdatesforPIs:
November1-4th:H3ABioNetSAB(1-2nd)andAnnualGeneralMeeting(3-4th),Cape
Town,SouthAfrica.
31stAugustisthedeadlineforthesumissionofyourfinalclaimsforyear4.
Anyupcomingeventsforthenexteditionofthenewslettermaybesendto
[email protected]@uct.ac.za
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H3ABioNetWorkingGroupMeetingScheduleuntilendAugust
2016
SummaryofH3ABioNetupcomingworkinggroupmeetings:
WorkingGroup Time DateMonth(2016)
Cloudcomputingtaskforcemeeting UTC=14:00 Thursday,11 August
RWSG UTC=11:00 Friday,12 August
H3ABioNetseminarseries UTC=13:00 Thursday,18 August
ISWG UTC=13:00 Friday,19 August
USWG UTC=9:00 Friday,26 August
E&TWG UTC=11:00 Tuesday,30 August
AcronymsusedforthevariousH3ABioNetworkinggroups:
E&TWG Educationandtrainingworkinggroup
RSWG Researchworkinggroup
ISWG Infrastructureworkinggroup
USWG Usersupportworkinggroup
NAWG Nodeaccreditationworkinggroup
TimezoneconversiontabletoUTCforallofH3ABioNetworkinggroupmeetings:
UTCTimeOffsetTimeZoneName
Regions/CountriesintheTimezoneoffset
-5hours CDT Chicago,USA
0hours GMT BurkinaFaso,Ghana,Mali,Morocco,Senegal
+1hour WATCameroon,Chad,Gabon,Namibia,Nigeria,Niger,Tunisia
+2hours CATBotswana,Egypt,Malawi,SouthAfrica,Sudan,Zambia
+3hours EAT Ethiopia,Kenya,Tanzania,Uganda
ThiseditionofthenewsletterwascompiledandeditedbyKimGurwitz.Forany
corrections,[email protected]