GlobalExcellenceinActionGraduateSchoolofInterdisciplinaryNewScience

ToyoUniversity

Graduate School of Interdisciplinary New Science Toyo University

2100, Kujirai, Kawagoe, Saitama 350-8585, Japan Tel: +81 49 239 1313 Fax: +81 49 231 5117 E-mail: fusion@toyo.jp URL: http://www.toyo.ac.jp/site/english-glns/

CourseofBio-NanoScienceFusionGraduateSchoolofInterdisciplinaryNewScienceToyoUniversity

Outline of the Graduate School of Interdisciplinary New Science The Graduate School of Interdisciplinary New Science, Toyo University, was opened in 2007 based on advanced research on bio-nano science and technology carried out at the Bio-Nano Electronics Research Centre, which was established in 1996. State-of-the-art facilities and equipment such as nanotechnology super clean rooms, biotechnology clean rooms, transmission electron microscopes, scanning electron microscopes, scanning probe microscopes and all sorts of spectroscopic analysers are installed at the Bio-Nano Electronics Research Centre. The main aim of the Graduate School is to educate and create advanced researchers in the fields of nanoscience/nanotechnology, bioscience/biotechnology and bio-nano fusion science/technology from an international point of view. The Graduate School provides a unique curriculum such as “Workshops on advanced equipment” and “Web educational programmes” as well as advanced lectures. The Graduate School also organises and holds international symposia, seminars and workshops for young researchers. The students carry out advanced research in collaboration with the Bio-Nano Electronics Research Centre, and overseas partner universities and research institutes. The Graduate School confers the Master and Doctoral Degrees of Bio-Nano Science Fusion on successful students. Admission policy The Graduate School of Interdisciplinary New Science accepts motivated Master and Doctoral Course students from all over the world and creates internationally advanced researchers in the fields of bioscience, nanotechnology and bio-nano fusion science and technology, the latter being one of the most important subjects in the 21st Century. An enquiring spirit of study on advanced subjects, an adventurous spirit for cutting-edge research areas, and high English communication ability and skill; i.e., writing, reading, discussions and presentations, are required. Educational policy All the educational courses; i.e., lectures, seminars, workshops, performance of research and preparation of scientific papers, theses and presentations, are given in English. The courses do not focus on only enumeration and memorisation of facts and the solutions to simple ready-made problems. In the classes, students are encouraged to discuss and give their own ideas and opinions on important scientific, technological, political, economical and social issues. Each student eventually writes and presents a thesis in English for her/his Master or Doctoral degree. Doctoral double degree programmes The Graduate School of Interdisciplinary New Science provides “Doctoral Double Degree Programmes” in collaboration with the following partner universities;

Sorbonne Université, Paris, France Université de Nantes, Nantes, France

Doctoral degrees are conferred on successful students from both Toyo University and one of the above partner universities. Supervisors

TatsuroHanajiriDesignandfabricationofnanoscaleelectrondevicesIamcurrentlystudyingthephysicsofnanoscaleelectrondevices and am interested in its application tonanoelectronics. I have studied the electric properties ofthin SOI films and the structures of SOIMOSFETswithdecanano scale gates. I propose fully inverted (FI) SOIMOSFETs with ultra-thin SOI films and novel fullydepleted(FD)SOIMOSFETs.

HisaoMorimotoSelf-organisation/nonlineardynamicsofnano/micromaterialsI am interested in self-organisations, phase transitions,and non-linear dynamics of nano/micro materialsdisperse systems such as suspensions, in whichnano/micro particles, carbon nanotubes, fullerenes orbiological cells are dispersed. I am also interested inbio-nano fusion technologies utilising the abovephenomena induced in nano/micro materials dispersesystems.

GlobalExcellenceinActionGraduateSchoolofInterdisciplinaryNewScience

ToyoUniversity

Visiting professors

DanielMorseUCSB

RéginePerzynski NicoleGrobert SilviaGiodarniLeonidKalachev

YoshioBandoNIMS

ShigeruDeguchiJAMSTEC

P.V.Mohanan

SakthiKumarBio-nanofusion/nanotechnology/biomaterialsI am interested in the research work based on fusion ofdifferent science fields, namely physics, chemistry andbiotechnology.Ifocusonresearchthemessuchas(a) Nano drug delivery, aptamer (DNA and RNA based)

sensorsandbio/chemicalsensors. (b) Carbon nanotubes, nano particles and quantum dots

for solar cell applications andplasmaprocessing thinfilms.

TomofumiUkaiSelf-organisationofnano/microparticlesI am interested in self-organisation, self-assembly andpattern formations of nano/micro particles. I am alsodeveloping microfluidic systems using nano/microparticles.Mycurrentresearchissummarisedbelow.(a) Patterns formedbymagnetic nano/micro particles in

externalmagneticfields.(b) Synthesisofmagneticnano/microparticles.

ShunjiKurosuCarbonnano-materials/self-assemblyI am very interested in the creation of newnano-structuresusingcarbonmaterialssuchasfullerenesandcarbonnanotubesviaself-organisation.Iparticularlyfocus on the pattern formation utilising the coffee ringeffect.Someofmyrecentstudiesarelistedbelow;(a) CreationofnanofibrescomposedofC60molecules.(b) Capture of target cancer cells using carbon

nano-structures

MohamedSheikhMohamedBio-NanoScience/CancerDiagnosis/Anti-CancerTherapyMy focus area of research involves synthesis ofbiocompatible nanomaterials and their applications inanimal and plant systems.I am particularlyinclinedtowardshardtotreatcancersasbraincancerandpancreaticcancer.(a) Bio-functionalizationofnanomaterialsforinvitroand

invivoapplications.(b) Formulatingnanomaterials

ToruMaekawaSelf-organisation/self-assemblyinnano/microsystemsI am very much interested in pattern formations,synchronisation and chaos created viaself-organisation/self-assembly, which are induced innano/micro systems. Fluctuations, surface effects andquantum effects, in particular, become significant onnanometre scales, which makes nano systemscompletelydifferentfromourmacroscopicworld.

ChrisEwels

BNERCToruMizukiBNERC

TakashiUchidaBNERC

KojiIshibashiRIKEN

CourseofBio-NanoScienceFusionGraduateSchoolofInterdisciplinaryNewScienceToyoUniversity

Curriculum (Master Course)

Year Type Title Credits

1

Lectures

Introductiontobio-nanosciencefusion 2

Englishforscienceandtechnology 2

Fundamentalmathematics 2

Fundamentalphysics 2

Fundamentalchemistry 2

Fundamentalbiotechnology 2

Extremophiles 2

Nanoelectronics 2

Nanomaterials 2

Biomaterialsandnanotechnology 2

Microbiology 2

Bionanoscience 2

Advancednanoscienceandnanotechnology 2

Workshops

WorkshoponadvancedequipmentI 2

WorkshoponadvancedequipmentII 2

WorkshoponadvancedequipmentIII 2

WorkshoponadvancedequipmentIV 2

Webprogramme WebeducationI 2

ResearchBio-nanosciencefusionseminarIandII 4

Bio-nanosciencefusionresearchIandII 4

2Webprogramme WebeducationII 2

ResearchBio-nanosciencefusionseminarIIIandIV 4

Bio-nanosciencefusionresearchIIIandIV 4

Web educational programmes: GEOSET TOYO The Graduate School of Interdisciplinary New Science produces, in collaboration with Florida State University, web educational programmes named “Global Educational Outreach for Science, Engineering and Technology, Toyo University” abbreviated to “GEOSET TOYO”. Students also participate in the production of GEOSET TOYO programmes. Some typical programmes are listed below;

Type Programmes LevelLecture+ppt

+videoFundamentalscience:Classicalmechanics

(Outline,philosophy,history)Undergraduate(UG)Graduate(Grad)

Lecture+ppt+video

Fundamentalscience:Classicalmechanics(Experimentalverification) UG,Grad

Lecture+ppt+video

Fundamentalscience:Electromagnetism(Outline,philosophy,history) UG,Grad

Lecture+ppt Fundamentalscience:Electromagnetism(Maxwellequation) UG,Grad,PD

Experiment+ppt+video

Observationofnanostructuresbyelectronmicroscopes UG,Grad,PD

Experiment+ppt+video

Observationofnanostructuresbyscanningprobemicroscopes UG,Grad,PD

Seminar+ppt+video

Roomtemperaturegrowthofcompoundsemiconductorslearningfromseacreatures

ProfessorDanielMorse

UG,Grad,PD,Researchers(R)

Seminar+ppt+video

SirHarryKroto’sInternationalSeminarforYoungScientists UG,Grad,PD,R

Video IntroductiontoCaliforniaNanoSystemsFacilitiesandequipment UG,Grad,PD,R

Video VisittotheRoyalSocietyGreatscientists UG,Grad,PD,R

Video SirHarryKroto’sSeminarforJuniorStudents Primary,Junior-highandHighSchool

GlobalExcellenceinActionGraduateSchoolofInterdisciplinaryNewScience

ToyoUniversity

Facilities and equipment State-of-the-art facilities and equipment are installed at the Bio-Nano Electronics Research Centre, which Master and Doctoral Course students can use for their research. A unique course such as “Workshops on advanced equipment” is specially designed for Master Course students.

NanostructuresProcessingRoom LithographyRoom NanoelectronicsSuperCleanRooms

TransmissionElectronMicroscope ScanningElectronMicroscopes

SuperconductingQuantumInterferenceDevice ScanningProbeMicroscope

UltraFastLiquidChromatography HardX-rayPhotoelectronSpectroscopySystem

CourseofBio-NanoScienceFusionGraduateSchoolofInterdisciplinaryNewScienceToyoUniversity

Events The Graduate School organises and holds international symposia, seminars and workshops for students both overseas and in Japan. The students also present their latest results at international symposia and seminars. International Symposia on Bioscience and Nanotechnology International Seminars for Young Scientists (overseas) International Seminars for Young Scientists (Bio-Nano Electronics Research Centre)

GlobalExcellenceinActionGraduateSchoolofInterdisciplinaryNewScience

ToyoUniversity

Sir Harry Kroto’s Seminars for Young Scientists (Kawagoe Campus) Recent publications Y.Nakajima,T.Ukai,T.Shimizu,K.Ogata,S. Iwai,N.Takahashi,A.Aki,T.Mizuki,T.MaekawaandT.Hanajiri,DetectionandanalysisoftargetedbiologicalcellsbyelectrophoreticCoultermethod,Anal.Chem.89,12450-12457(2017).DOI:10.1021/acs.analchem.7b03533S.Raveendran,A.K.Rochani,T.MaekawaandD.S.Kumar,Smartcarriersandnanohealers:Ananomedicalinsightonnaturalpolymers,Materials10,929(2017).DOI:10.3390/ma10080929S. Iwai,S.Kurosu,H.Sasaki,K.KatoandT.Maekawa,Trappingandproliferationof targetcellsonC60 fullerenenanofibres,Heliyon3,e00386(2017). DOI:10.1016/j.heliyon.2017.e00386N. Chauhan, T. Maekawa and D.S. Kumar, Graphene based biosensors - Accelerating medical diagnostics tonew-dimensions,J.Mater.Res.32,2860-2882(2017).DOI:10.1557/jmr.2017.91S. Balasubramanian, G.A. Ravindran, R. Romero-Aburto, T.Mitcham, K.A.Mitchel,Y. Nagaoka, R.R. Bouchard,P.M. Ajayan, T. Maekawa and D.S. Kumar, Highly versatile SPION encapsulated PLGA nanoparticles asphotothermalablatorsofcancercellsandasmultimodalimagingagents,Biomater.Sci.5,432-443(2017).DOI:10.1039/C6BM00621CS.Raveendran,A.Sen,T.MaekawaandD.S.Kumar,Ultra-fastmicrowaveaidedsynthesisofgoldnanocagesandstructuralmaneuverstudies,NanoRes.10,1078-1091(2017).DOI:10.1007/s12274-016-1368-3H.Shimoshige,Y.Nakajima,H.Kobayashi,KYanagisawa,Y.Nagaoka,S.Shimamura,T.Mizuki,A. InoueandT.Maekawa,Formationofcore-shellnanoparticlescomposedofmagnetiteandsamariumoxideinMagnetospirillummagneticumstrainRSS-1,PLoSOne12,e0170932(2017).DOI:10.1371/journal.pone.0170932M. Sheikh, A. Torabi, M. Paulose, D.S. Kumar and O. Varghese, Anodically grown titania nanotube inducedcytotoxicityhasgenotoxicorigins,Sci.Rep.7,41844(2017).DOI:10.1038/srep41844M.Suzuki,H.Hayashi,T.Mizuki,T.MaekawaandH.Morimoto,EfficientDNAligationbyselectiveheatingofDNAligasewitha radiofrequencyalternatingmagneticfield,Biochem.Biophys.Rep.8,360–364(2016).DOI:10.1016/j.bbrep.2016.10.006A.C. Poulose, S. Veeranarayanan, M.S. Mohamed, R.R. Aburto, T. Mitcham, R.R. Bouchard, P.M. Ajayan, Y.Sakamoto, T. Maekawaand D.S. Kumar, Multifunctional Cu2-xTe nanocubesmediated combination therapy formulti-drugresistantMDAMB453,Sci.Rep.6,35961(2016).DOI:10.1038/srep35961Y. Hayasaki, T. Hasumura, T. Fukuda, Y. Nagaoka, T. Ukai, S. Iwai, T. Uchida and T. Maekawa, Synthesis ofmagneticalloy-fillingcarbonnanoparticlesinsuper-criticalbenzeneirradiatedwithanultravioletlaser,Heliyon2,e00171(2016).DOI:10.1016/j.heliyon.2016.e00171A.K.Rochani,B.Sivakumar,R.G.Aswathy,S.Raveendran,A.Borah,Y.Nagaoka,Y.Nakajima,T.MaekawaandD.S. Kumar, Dual mode of cancer cell destruction for pancreatic cancer therapy using Hsp90 inhibitor loadedpolymericnanomagneticformulation,Int.J.Pharm.511,648-658(2016).DOI:10.1016/j.ijpharm.2016.07.048

CourseofBio-NanoScienceFusionGraduateSchoolofInterdisciplinaryNewScienceToyoUniversity

Internationalcollaborationonresearchandeducationalprogrammes The Graduate School of Interdisciplinary New Science has been carrying out collaborativeresearchonnanoscience/technology,bioscience/technologyandbio-nanoscience/technologywith advanced researchers andhas exchangedMemorandaofUnderstandingon “Bio-NanoInnovationProgrammes”with19universitiesand10companies. Universities

UK UniversityofBrighton / UniversityofOxford

France UniversityofNantes / SorbonneUniversityUSA UniversityofCaliforniaSantaBarbara / UniversityofMontana

RiceUniversity / UniversityofHoustonIndia IndianInstituteofTechnologyDelhi / IndianInstituteofTechnologyMadras

SreeChitraTirunalInstituteforMedicalSciencesandTechnologyMahatmaGandhiUniversity / JawaharlalNehruUniversity

Italy ItalianInstituteofTechnology / UniversityofTurinHungary BudapestUniversityofTechnologyandEconomics

Romania PolitehnicaUniversityofTimisoaraMalaysia UniversitiTeknologiMalaysiaOman SultanQaboosUniversity

Industries

Japan JEOL Ltd. / Shimadzu Co. / Horiba Co. / Oxford Instruments KK.

ElionixInc. / SamcoInc. / NissanARCLtd. / Ulvac-PhiInc.HitachiHigh-TechnologiesCo.

USA OxfordInstrumentsAsylumResearchInc.

GraduateSchoolofInterdisciplinaryNewScienceEducationandStudentAffairsSection,KawagoeCampus,ToyoUniversity

2100,Kujirai,Kawagoe,Saitama350-8585,JapanTel:+81-49-239-1313,Fax:+81-49-231-5117,E-mail:fusion@toyo.jpURL:http://www.toyo.ac.jp/site/english-glns/

Bio-NanoElectronicsResearchCentre,ToyoUniversityResearchPromotionSection

2100,Kujirai,Kawagoe,Saitama350-8585,JapanTel:+81-49-239-1375,Fax:+81-49-234-2502,E-mail:bnel@toyo.jpURL:http://www.toyo.ac.jp/site/bionano/

Enquiriesconcerningthegraduateschool

Enquiriesconcerningresearchprojects

Secretariat of the Bio-Nano Electronics Research Centre, Toyo University

Akiko Tanaka Mikiko Koizumi Hiroshi Akasu Minako Hardy Koichi Nishina

Keiko Itamochi Katsumi Funato Takuzo Kakimori Eri Nagatsuka Natsue Takahashi

Secretariat of the Graduate School of Interdisciplinary New Science, Toyo University