global breast cancer burden | the cancer...

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3 Canceratlas.cancer.org Copyright © 2014 The American Cancer Society, Inc. Canceratlas.cancer.org Copyright © 2014 The American Cancer Society, Inc. 9 . 1 8. 3 5 .8 0.8 1 3 .5 9 . 2 9 . 4 2 5.2 1 8 . 8 9 . 1 5. 6 4 .9 1 .1 8 .6 1 1 . 2 1 5 . 3 27 .7 1 6 . 5 Breast cancer incidence rates continue to increase in all countries except a few high-income countries, while mortality rates are decreasing in many high-income countries and increasing in low- and middle-income countries. AGE-STANDARDIZED INCIDENCE AND MORTALITY RATES (WORLD) PER 100,000 FOR SELECT COUNTRIES, 1975-2011 76.3 or more No Data 55.8 — 76.2 39.7 — 55.8 26.0 or less 26.01—39.6 Female Breast Cancer Mortality ESTIMATED AGE-STANDARDIZED RATE (WORLD) PER 100,000 POPULATION, 2012 20.8 or more No Data 16.0 — 20.7 12.1 — 15.9 8.1 or less 8.2—12.0 12 THE BURDEN 1 Breast cancer is the most common cancer in women worldwide, with slightly more cases estimated in 2012 in less-developed (883,000 cases) than in more-developed (794,000) regions. Of the 184 countries included in the GLOBOCAN database, breast cancer is the most common cancer diagnosis in women in 140 countries (76%) and the most frequent cause of cancer mortality in 101 countries (55%). 3 Incidence rates vary nearly fourfold across the world regions, ranging from 27 per 100,000 in Middle Africa and Eastern Asia to 96 per 100,000 in Western Europe, and tend to be elevated in countries with highest development. Breast cancer is the most frequent cause of cancer death in women in less-developed regions (324,000 deaths, 14.3% of total) and the second cause of cancer death in more-developed regions (198,000 deaths, 15.4%), after lung cancer. 2 Incidence rates continue to increase in all countries except in a few high-income countries. In contrast, mortality rates are decreasing in many high-income countries but increasing in low- and middle-income countries. BREAST CANCER Breast cancer is by far the most frequently diagnosed cancer and cause of cancer death among women worldwide. “People used to say everyone knows someone who’s had breast cancer. In the past few weeks, I’ve learned something else: Everyone has someone close to them who has had breast cancer.” Debbie Wasserman Schultz, US House of Representatives, breast cancer survivor Although the estimated number of breast cancer deaths is less than a third of estimated new cases, breast cancer is the most common cause of cancer death in women in less-developed countries, and the second among women in developed countries. ESTIMATED NEW BREAST CANCER CASES AND DEATHS BY REGION, 2012 1 There were an estimated 1.7 million new cases (25% of all cancers in women) and 0.5 million cancer deaths (15% of all cancer deaths in women) in 2012. 2 High-income Lower middle income Australia Denmark India Japan The variation in mortality rates between world regions (ranging from 6 per 100,000 in Eastern Asia to 20 per 100,000 in Western Africa) is less than that for incidence rates because of the considerably better survival from breast cancer in developed regions, resulting from increased access to early detection (mammography) and treatment. Differences in incidence between countries with and without mammography screening programs are also influenced by earlier diagnosis and the overdiagnosis associated with detecting breast cancers in asymptomatic women. Overall, a substantially greater proportion of women with breast cancer will die from their disease in less-developed regions. TOTAL ESTIMATED CASES 1,700,000 TOTAL ESTIMATED DEATHS 522,000 India China Other East & Central Asia Europe Northern America Latin America & Caribbean Sub-Saharan Africa Middle East & North Africa Oceania | | | | 1980 1990 2000 2010 | | | | 1980 1990 2000 2010 INCIDENCE 120— 100— 80— 60— 40— 20— RATE PER 100,000 Australia Denmark Guatemala Israel MORTALITY 30— 25— 20— 15— 10— 5— RATE PER 100,000 Sub-Saharan Africa Middle East & North Africa Europe Oceania Northern America East & Central Asia Latin America & the Caribbean India China 17.2 16.2 16.1 15.6 14.8 13.7 13 12.7 5.4 Although incidence rates are highest in developed regions, mortality rates in these areas are comparable to most of the less- developed regions. ESTIMATED AGE-STANDARDIZED FEMALE BREAST CANCER INCIDENCE RATE (WORLD) PER 100,000, 2012 Northern America Oceania Europe Latin America & the Caribbean Middle East & North Africa East & Central Asia Sub-Saharan Africa India China 91.6 79.2 71.1 47.2 43.0 38.3 33.8 25.8 22.1 Female Breast Cancer Incidence ESTIMATED AGE-STANDARDIZED RATE (WORLD) PER 100,000 POPULATION, 2012 ESTIMATED AGE-STANDARDIZED FEMALE BREAST CANCER MORTALITY RATE (WORLD) PER 100,000, 2012 % %

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Page 1: Global Breast Cancer Burden | The Cancer Atlascanceratlas.cancer.org/assets/uploads/2014/10/12_BreastCancer_rev... · Title: Global Breast Cancer Burden | The Cancer Atlas Subject:

3

“Canceratlas.cancer.org

Copyright © 2014 The American Cancer Society, Inc.Canceratlas.cancer.org Copyright © 2014 The American Cancer Society, Inc.

9.1

8.3

5.8 0.8 13.5 9.2

9.4

25.2

18

.8

9

.1

5.6

4.9 1.1 8.6 11.2

15.3

27.7

16.

5

Breast cancer incidence rates continue to increase in all countries except

a few high-income countries, while mortality rates are decreasing in many

high-income countries and increasing in low- and middle-income countries.

AGE-STANDARDIZED INCIDENCE AND MORTALITY RATES (WORLD) PER 100,000 FOR SELECT COUNTRIES, 1975-2011

76.3 or more No Data55.8 — 76.239.7 — 55.826.0 or less 26.01—39.6

Female Breast Cancer Mortality

ESTIMATED AGE-STANDARDIZED RATE

(WORLD) PER 100,000 POPULATION, 2012

20.8 or more No Data16.0 — 20.712.1 — 15.98.1 or less 8.2—12.0

12 THE BURDEN1 Breast cancer is the most common cancer

in women worldwide, with slightly more cases estimated in 2012 in less-developed (883,000 cases) than in more-developed (794,000) regions. Of the 184 countries included in the GLOBOCAN database, breast cancer is the most common cancer diagnosis in women in 140 countries (76%) and the most frequent cause of cancer mortality in 101 countries (55%). 3 Incidence rates vary nearly fourfold across the world regions, ranging from 27 per 100,000 in Middle Africa and Eastern Asia to 96 per 100,000 in Western Europe, and tend to be elevated in countries with highest development. Breast cancer is the most frequent cause of cancer death in women in less-developed regions (324,000 deaths, 14.3% of total) and the second cause of cancer death in more-developed regions (198,000 deaths, 15.4%), after lung cancer. 2 Incidence rates continue to increase in all countries except in a few high-income countries. In contrast, mortality rates are decreasing in many high-income countries but increasing in low- and middle-income countries.

BREAST CANCERBreast cancer is by far the most frequently diagnosed cancer and cause of cancer death among women worldwide.

“People used to say everyone knows someone who’s had breast cancer. In the

past few weeks, I’ve learned something else: Everyone has someone close to them who

has had breast cancer.”

— Debbie Wasserman Schultz, US House of Representatives,

breast cancer survivor

Although the estimated number of breast cancer deaths is less than a third of estimated new cases, breast cancer is the most

common cause of cancer death in women in less-developed countries, and the second among women in developed countries.

ESTIMATED NEW BREAST CANCER CASES AND DEATHS BY REGION, 2012

1

There were an estimated 1.7 million new cases (25% of all cancers in women) and 0.5 million cancer deaths (15% of all cancer deaths in women) in 2012.

2

High-income

Lower middle income

Australia

Denmark

India

Japan

The variation in mortality rates between world regions (ranging from 6 per 100,000 in Eastern Asia to 20 per 100,000 in Western Africa) is less than that for incidence rates because of the considerably better survival from breast cancer in developed regions, resulting from increased access to early detection (mammography) and treatment. Differences in incidence between countries with and without mammography screening programs are also influenced by earlier diagnosis and the overdiagnosis associated with detecting breast cancers in asymptomatic women. Overall, a substantially greater proportion of women with breast cancer will die from their disease in less-developed regions.

TOTAL ESTIMATED CASES

1,700,000TOTAL ESTIMATED DEATHS

522,000

India

China

Other East & Central Asia

Europe

Northern America

Latin America & Caribbean

Sub-Saharan Africa

Middle East & North Africa

Oceania

| | | |1980 1990 2000 2010

| | | |1980 1990 2000 2010

INCIDENCE

120—

100—

80—

60—

40—

20—

RAT

E P

ER

10

0,0

00

Australia

Denmark

Guatemala

Israel

MORTALITY

30—

25—

20—

15—

10—

5—

RAT

E P

ER

10

0,0

00

Sub-Saharan Africa

Middle East & North Africa

Europe

Oceania

Northern America

East & Central Asia

Latin America & the Caribbean

India

China

17.216.216.115.614.813.7

1312.75.4

Although incidence rates are highest in developed regions,

mortality rates in these areas are comparable

to most of the less-developed regions.

ESTIMATED AGE-STANDARDIZED FEMALE BREAST CANCER INCIDENCE RATE (WORLD) PER 100,000, 2012

Northern America

Oceania

Europe

Latin America & the Caribbean

Middle East & North Africa

East & Central Asia

Sub-Saharan Africa

India

China

91.679.271.147.243.038.333.825.822.1

Female Breast Cancer Incidence

ESTIMATED AGE-STANDARDIZED RATE

(WORLD) PER 100,000 POPULATION, 2012

ESTIMATED AGE-STANDARDIZED FEMALE BREAST CANCER MORTALITY RATE (WORLD) PER 100,000, 2012

%%