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Medicine. Noyes Publications, Park Ridge, NJ, 1985, xxi + 477 pp. ($72.00) ISBN o-8155-1034-9.

(Fifty contributors; 23 chapters. Monoclonal anti- body production; lymphocyte subpopulation in rodents; separation of lymphocyte subpopulations by monoclonal antibodies; immunofluorescence; phenotyping of human NK cells; myelomonocytic cells; human T-cell surface structures; enzymology; complement components; coagulation; human chorionic gonadotropin; viruses; Herpes simplex

virus infections; bacteria; diagnostic pathology; detection of malignancies; melanomas; human lymphoproliferative malignancies; human histocom- patibility antigens; therapy of renal transplant rejec- tion; therapeutic tools in medicine; malignant diseases; conjugates as active therapy; commercial monoclonal antibodies).

B.N. Fields, D.M. Knipe, R.M. Chanock, J.L. Melnick, B. Roizman and R.E. Shope (Eds.): Virology. Raven Press, New York, 1985, xiv + 1614 pp. ($149.50) ISBN 0-88167-026-X.

[A monumental monograph of 63 chapters with 64 contributors. The following aspects of virology are ably presented in separate chapters: taxonomy; structure; membranes; multiplication; generation and replication of defective genomes; animal virus genetics; molecular genetics; epidemiology; trans- mission of disease; pathogenesis; metabolism; cellu- lar architecture; transformation and oncogenesis (DNA viruses, retroviruses); host response; interfe- rons; diagnostics; antiviral chemotherapy; immuni- zation; papovaviruses; parvoviruses; adenoviruses (replication, diseases); herpes viruses; herpes sim- plex; Epstein-Barr virus; varicellazoster virus; cy- tomegalovirus; poxviruses; picornaviruses; entero- viruses (polio, coxsackie, echo and newer enterovi- ruses); rhinoviruses; reoviruses; rotaviruses; orbivi- ruses; togaviruses; alphaviruses; flaviviruses; rubel- la; arena viruses; bunyaviruses; Marburg and Ebola viruses; rhabdoviruses; rabies virus; orthomyxovi- ruses; paramyxoviruses; influenza; parainfluenza; mumps ; respiratory syncytial viruses; measles; coronaviruses; T-cell leukemia viruses; viral hepatitis; Norwalk group of viruses; viruses causing subacute spongiform encephalopathies].

R.C. Gallo, D. Stehelin and O.E. Vamier (Eds.): Retroviruses and Human Pathology. (Proceedings of

the International Symposium on Retroviruses and Human Pathology, San Terenzo di Lerici, La Spezia, Italy, Sept. 24-26, 1984) Experimental Biology and Medicine Series, Humana Press, Clifton, NJ, 1985, xviii + 557 pp. ($74.50) ISBN o-89603-098-9.

[ 179 authors; 48 articles. Role of retroviruses: in neoplasia, in nature. W.P. Rowe Memorial Lecture: Changing dogmas in retrovirology (J.A. Levy). Re- troviruses and murine model system endogenous leukemia viruses, xenotropic retroviruses, computer age, mammary tumorigenesis, proviral genome of radiation leukemia virus, Friend leukemia cells, envelope gene, MHC, MMTV, antiviral drugs. Re- troviruses and the Vertebrate Model System: onco- genes in rats, avian leukemia viruses, feline retrovi- ruses, bovine leukemia virus, ultraviolet-induced retroviruses, susceptibilities to 2-deoxy-D-glucose, functional heterogeneity, rat sarcoma Galliera. Re- troviruses and Human Pathology: HTLV viruses, retroviral genes in human reproductive tissue, AIDS, T-cell leukemia, LTRs of leukemia viruses, LAV proteins, lymphocyte immune functions, anti- ,HTLV-III and anti T-cell antibodies, seroepidemio- logical study of LAV by ELISA in AIDS, antibodies to SAIDS, retroviruses expressed during oocyte maturation, psoriasis, human milk RNase, slow in- fections. Retroviruses and oncogenes: retroviruses with two oncogenes, ras oncogenes, raf oncogene, cell attachment, amplification of oncogenes, nucle- otide sequence of erbA, osteosarcoma oncogene, c-myc gene, fes oncogene, myc and myb oncogenes, detection of oncogene transcripts].

A.T. Ganesan and J.A. Hoch (Eds.): Genetics and

Biotechnology of Bacilli (Proceedings of the Second International Conference on the Genetics and Biotechnology of Bacilli, Stanford University, Stan- ford, CA, July 6-8, 1983) Academic Press Inc., Orlando, FL, 1984, xviii + 421 pp. ($41.50) ISBN O-12-274 60-9.

[The integrated prophage (A.M. Campbell); sca- tology and biotechnology (S. Falkow). Chromoso-

mal organization: ribosomal and transfer RNA genes; replication origin and terminus; membrane; gene amplification; cloning and gene fusion; Tn917 insertional mutagenens; sucrose system. Secretion: B-lactomases; levansucrase; secretion vectors; serin protease; sub&in control; cr-amylase promoter and signal peptide. Transcription: phage +29; temporally

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expressed promoter; lipiarmycin as inhibitor of RNA polymerase; phage SPPl as vector. Cloning: inducible promoter; thiol-activated cytolysin; chlo- ramphenicol inducibility; stability of bifunctional plasmid; cloning in Bacilli; chromogenic detection. Synthesis of sporulation-associated products : clon- ing and sequence of the spooA locus (F. Ferrari and J. Hoch); amplification of sporulation genes; Bacillus

thuringiensis. Phage (H. Hirokawa, T. Trautner). Spores (G.H. Chamblis et al.). General genetics (J.-C. Alonso, R. Yasbin)].

H.S. Ginsberg and H.J. Vogel (Eds.): Transfer and Expression of Eukaryotic Genes. Academic Press, Inc., Orlando, FL, 1984, xxiii + 304 pp. ($65.00). ISBN o-12-284650-8.

(84 authors; 25 articles. Sol Spiegehnan’s obitua- ry; molecular basis of gene expression (D.D. Brown). Gene expression and its regulation: SV40 enhancer; cloned alcohol dehydrogenase in Droso-

phila. DNA methylation and globin gene expression; histone gene transcription; control of fl-globin trans- cription; transcriptional enhancement; introns in murine kappa light chain genes. In vivo gene transfer and development : Drosophila ; sea urchin ; transgenic mouse; gene transfer into mice; surface receptors; nuclear transplantation; neuropeptide genes; ho- mologous recombination in L cells. Viral gene and oncogene systems: splicing of mRNA; regulation of thymidine kinase expression; control of a genes of HSVl; early adenovirus transcription; mutational analysis of Ad5Ela gene; adenovirus VA1 RNA- translational enhancer; early SV40 transcription; transforming genes of chicken and human B cell lymphomas ; myc oncogene).

R.F. Goldberger and K.R. Yamamoto (Eds.): Biological Regulation and Development (Vol. 3A, Hormone Action). Plenum Press, New York and London, 1982, xiv + 346 pp. ($39.50) ISBN o-306-40925-9.

[History of hormones (A. White and R. Levine); system analysis of hormone action (F.E. Yates); analysis of metabolic networks (J.J. Blum and R.B. Stein); neuroendocrine interrelationships (I.M.D. Jackson and G.P. Mueller); estrogens, brain cell functions, and behaviour (B.S. McEven); trans- membrane-mediated communication (G.L. Nicol- son); hormonal control of NaCl and water transport

in epithelia (A. Taylor and L.G. Palmer); metabolism of cell surface receptors - possible roles in cell sensitivity and responses to activators (J.M. Gardner and D.M. Fambrough)]. M.M. Gottesman (Ed.): Molecular Cell Genetics. Wiley and Sons, New York, 1985, xvi + 931 pp. ($19.95) ISBN O-471-87925-8.

[ 37 contributors; 29 articles, 2 appendices. Devel- opment and characterization of Chinese hamster cell lines (CHO); genetic manipulation CHO lines; genetic systems developed in CHO lines; inter- mediary metabolism; cell structure and behaviour; mechanism of genetic variation; lineages of CHO lines; CHO cell mutants].

J.G. Gunsalus, J.R. Sokatch and L.N. Omston (Eds.): The Bacteria, A Treatise on Stxucture and Function [Vol. X, The Biology of Pseudomonas.]

Academic Press, Inc., Orlando, FL 32887, 1986, xiii + 617 pp. ($95.00) ISBN o-12-307210.

(I. Biology: taxonomy of the Pseudomonas; control of Pseudomonas pulida growth on agar surfaces; evolution of enzyme structure and function in Pseudomonas; outer membrane permeability of Pseudomonas aeruginosa; toxins and virulence fac- tors of Pseudomonas aenqinosa. II. Genetics: chro- mosome mobilization and genomic organization in Pseudomonas; regulation of tryptophan synthesis in Pseudomonas; resistance plasmids of Pseudomonas;

degradative plasmids in Pseudomonas; gene cloning and manipulation in Pseudomonas; cloning of Pseudomonas genes in Escherichia coli. III. Bio- chemistry: biosynthetic and catabolic features of amino acid metabolism in Pseudomonas; catabolic potential of Pseudomonas cepacia ; terpenoid metabo- lism by Pseudomonas; biochemistry of aromatic hydrocarbon degradation in Pseudomonas; Pseu-

domonas cytochromes P-450).

J.P. Gustafson, G.L. Stebbins and F.J. Ayala (Eds.): Genetics, Developmat, and Evolution. 17th Stadler Genetics Symposium. Plenum Press, New York and London. 1986, xii + 361 pp. ($49.50) ISBN o-306-42268-9.

(26 contributors; 15 articles. Evolution and mor- phogenesis, gene action and morphogenesis in plants, mobile elements in maize, mutation, apical meristems and developmental selection in plants, properties of mutable alleles recovered from mutator