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TRANSCRIPT
Food&Beverage Overview
June 2018
1Market Highlights
Source: Frost & Sullivan
The global antioxidants
market was valued at
$377m in 2016 and is
expected to reach $486
in 2021, a 5.2% CAGR
Antioxidants Market
Demand for Flavour
Delivery Technologies is
driven by the growing
need for slow release
solutions
Flavour Delivery
Technologies
The global curcumin 95%
market was valued at
$49m in 2016 and is
expected to reach $101
in 2023, a 12.6% CAGR
Curcumin Market
Demand for Food Safety
Technologies is driven by
increasing incidences off
foodborne illnesses
Food Safety
Technologies
The global personal care
active ingredients market
was valued at $3.5b in
2016 and is expected to
reach $5.6b in 2023, a
6.9% CAGR
Personal Care Active
Ingredients Market
Growth in Antimicrobial
Technologies is driven by
ongoing concern about
the level of healthcare-
associated infection
Antimicrobial
Technologies
The global prebiotic
ingredients market was
valued at $1.5b in 2016
and is expected to reach
$1.8b in 2021, a 5.4%
CAGR
Prebiotic Ingredients
Market
The global probiotics
market was valued at
$1.3b in 2016 and is
expected to reach $1.8b
in 2021, a 6.8% CAGR
Probiotic Ingredients
Market
Urban farming is
expected to help meet
the nutritional
requirements of a rapidly
growing population
Urban Farming
Innovations
Market Trend #1
Antioxidants Market
2
Source: Frost & Sullivan
The global antioxidants market was valued at $377m in 2016 and is expected to reach $486 in 2021, a 5.2% CAGR; natural extracts
and new delivery & dosage forms are expected to offer opportunities
Size Technologies
Revenues, Global, 2016-21 Example innovations
New
Delivery
Forms of
Lutein and
Zeaxanthin
Antioxidants
Novel
Fungi-
based
Antioxidant
Derived
from
Mushroom
377,1
433,8
485,7
0
100
200
300
400
500
2016 2019 2021
5.2% CAGR 2016-21
Re
ve
nu
es
$ m
Market Trend #2
Flavour Delivery Technologies
3
Source: Agdot, CPL Aromas, Frost & Sullivan
Demand for Flavour Delivery Technologies is driven by the growing need for slow release solutions; UK start-ups have received
funding to support their research and commercialisation activities
Trends Start-ups
Example fundraisings
Demand for Long-lasting Effects
Encapsulation is used to make flavor providing ingredients
that are slowly released during the cooking process or while
chewing food products
Increasing Investments to Enhance Product Capabilities
With companies increasing their R&D investments toward
enhancing product capabilities, novel encapsulation
technologies are being developed
Preference for Signature Products
Consumers gravitate toward products that provide a distinct
flavor or fragrance, using unique and natural raw
ingredients, such as vanilla or ylang-ylang
Key drivers, Global
Focus on New Product Development
• In February 2016, Aqdot (UK) raised $6.7 million series A funding for the
commercialization of its Aqdot™ encapsulation technology platform. The
technology can be used for controlled delivery of fragrances in household
and industrial applications
• In August 2017, CPL Aromas (UK) launched a new R&D center worth $1.4
million in Brixworth (UK). The new R&D facility comes equipped with an
Encapsulation Lab for creating liquid encapsulated fragrances that can be
used in new perfume formulations
Europe
Market Trend #3
Curcumin Market
4
Source: Frost & Sullivan
The global curcumin 95% market was valued at $49m in 2016 and is expected to reach $101 in 2023, a 18.1% CAGR; growth is
primarily stemming from supply-side innovations
Size Trends
Revenues, Global, 2016-23 Key drivers, Global
Drivers 1-2 Years 3-4 Years 5th Year
Increasing R&D
activity
Growing applications
as no side effects
Evidence of disease
prevention
43,9
68,7
100,8
0
25
50
75
100
125
2016 2020 2023
18.1% CAGR 2016-23
Re
ve
nu
es
$ m
Market Trend #4
Food Safety Technologies
5
Source: Frost & Sullivan
Demand for Food Safety Technologies is driven by increasing incidences off foodborne illnesses; enabling intervention technologies
include bio-illumination, plasma and thermal solutions
Trends Technologies
Key drivers, Global Key enablers
Foodborne illness concerns driving authorities to promote new
regulations
According to the US Center of Disease Control and Prevention, foodborne
illness affects more than 48 million Americans each year, accounting over
100,000 hospitalizations and thousands of deaths
High
1
23
4
5
<1 >5
Low
3
High
1
2 4
5
<1 >5
LowShort term Long term
Bio-illumination
Molecular pathogen detection systems are based on isothermal DNA
amplification and ATP bioluminescence detection technologies
Plasma
Cold plasma is a non-thermal “green” technology that uses energetic,
reactive gases to inactivate contaminating microbes on meats
Thermal
Thermal processing plays a key role in keeping food safe from
contamination while remaining high in nutritional and sensory attributes
Market Trend #5
Personal Care Active Ingredients Market
6
Source: Geneu, Romy, Frost & Sullivan
The global personal care active ingredients market was valued at $3.5b in 2016 and is expected to reach $5.6b in 2023, a 6.9%
CAGR; technology has enabled the development of new beauty tools
Size Technologies
Revenues, Global, 2016-23 Example innovations
3,5
4,6
5,6
0,0
1,0
2,0
3,0
4,0
5,0
6,0
2016 2020 2023
6.9% CAGR 2016-23
Re
ve
nu
es
$ b
GeneU, England, and
and SKINSHIFT, US, sell
DNA tests that analyze
the skin
Romy, France, offers a
“beauty assistant” which
blends active ingredients
into a serum or cream
Market Trend #6
Antimicrobial Technologies
7
Source: Frost & Sullivan
Growth in Antimicrobial Technologies is driven by ongoing concern about the level of healthcare-associated infection; companies are
developing uses for metallic ions across many application areas
Trends Metallic ions
Key drivers, Global Key applications
There is a growing use of polymeric and metallic
antimicrobial platforms
Healthcare-associated infection (HAI) continues to
be a significant global concern
Awareness about the use of natural ingredients (vs.
harsh antimicrobials) is growing
2
1
3
Industry Segment Application Areas
Medical DevicesCatheters, Implants, Endoscopes,
Touch Surfaces
Food & Beverages Food Grade Metal Coatings
Personal Care & Hygiene Handwash, Soaps
Industrial, Building & Construction HVAC, Metal Cladding, Paints
Drivers 1-2 Years 3-4 Years 5th Year
Consumer trends;
clean and clear label
Closing the fibre gap
Increasing R&D and
awareness of benefits
Market Trend #7
Prebiotic Ingredients Market
8
Source: Frost & Sullivan
The global prebiotic ingredients market was valued at $1.5b in 2016 and is expected to reach $1.8b in 2021, a 5.4% CAGR;
prebiotics help consumers to close the fibre gap
Size Trends
Revenues, Global, 2016-21
1,4
1,6
1,8
0,0
0,5
1,0
1,5
2,0
2016 2019 2021
5.4% CAGR 2016-21
Re
ve
nu
es
$ b
Key drivers, Global
Market Trend #8
Probiotic Ingredients Market
9
Source: Vésale Pharma , Nebraska Cultures, Frost & Sullivan
The global probiotics market was valued at $1.3b in 2016 and is expected to reach $1.8b in 2021, a 6.8% CAGR; developments in,
for example, microencapsulation and stability are driving the market
Size Technologies
Revenues, Global, 2016-21 Example innovations
1,3
1,6
1,8
0,0
0,5
1,0
1,5
2,0
2016 2019 2021
Re
ve
nu
es
$ b
6.8% CAGR 2016-21
Vésale Pharma, a Belgian company, has developed a new
technology platform for microencapsulation of probiotics called
intelicaps
According to a scientific study by the University of Nebraska,
ProDURA by Nebraska Cultures (US) was able to demonstrate
superior heat resistance compared to other strains of Bacillus
coagulants
Market Trend #9
Urban Farming Innovations
10
Source: Frost & Sullivan
Urban farming is expected to help meet the nutritional requirements of a rapidly growing population; greenhouse farming is one of
the main commercial urban farming solutions
Market Greenhouses
Key classifications Future prospects
Commercial Urban Farming
Vertical Farming
Aeroponics Hydroponics Aquaponics
Greenhouse Farming
Implementation of appropriate future technologies associated
with greenhouses including autonomous systems and
utilization of renewable energy will result in high return on
investment and will also enable optimum use of natural
resources to obtain high yield per acre inside the greenhouse.
These factors also increase the quality and longevity of the
crops cultivated
11
...
• TBC
Antioxidants Market
12Antioxidants stem from natural or synthetic ingredients; the former is the largest
($272m in 2016) and fastest growing (5.7% CAGR 2016-21) segment
Source: Frost & Sullivan
Natural Ingredients
• Rosemary extracts are derived from Rosmarinus officinalis L. and
contain several compounds which have been proven to exert
antioxidative functions. These compounds belong mainly to the
classes of phenolic acids, flavonoids, diterpenoids and triterpenes
• Mixed tocopherols are defined as a source of Vitamin E derived by
the vacuum distillation of vegetable oils or their by-products
Synthetic Ingredients
• Butylated Hydroxyanisole is a combination of the isomeric
compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-
hydroxyanisole and used as an additive in food and beverages for its
antioxidant properties
• Butylated Hydroxytoluene is an organic compound derived from
phenol and is used widely in food and cosmetic products for its
antioxidant properties. Use of BHT prevents oils in foods from
oxidizing
• Tertiary Butyl Hydroquinone is derived from phenol and is
commonly used in food products
• Ascorbyl Palmitate is a fat-soluble form of Vitamin C derived from
ascorbic acid and palmitic acid and used as an antioxidant additive in
food
• Propyl Gallate is formed by the condensation of gallic acid and
propanol and used as an antioxidant in food products containing oils
and fats to prevent oxidation
En
d A
pp
licati
on
s i
n F
oo
d
Oil and Fats
Meat and Poultry
Bakery and Confectionery
Dairy
Others (frozen foods, desserts and salads)
13The market is buoyant thanks to the widespread use of antioxidants in animal feed
and increased demand from the pharma & cosmetics industries
Source: Frost & Sullivan
Drivers 1-2 Years 3-4 Years 5th Year
Shifting consumer preferences for ready-to-eat food products M H H
Increasing consumption of meat products and significance of
antioxidants in animal feedM M H
Demand from pharmaceutical and cosmetics industries M M H
Restraints 1-2 Years 3-4 Years 5th Year
Stringent government regulations and bans impeding market
growthM M L
Lack of understanding and awareness among consumers on
the importance of antioxidantsM L L
Antioxidants Market: Market Drivers and Restraints, Global
Impact Ratings: H = High, M = Medium, L = Low
14Growth is also being driven by shifting consumer preferences; antioxidants are widely
used to avoid spoilage in popular ready-to-eat food products
Source: Frost & Sullivan
Shifting Consumer Preferences for Ready-to-eat Food Products
• Antioxidants are used as additives and in a wide range of applications such as fats and oils
and in food processing industries to prevent food spoilage. Scientific evidences show that
spices and some herbs are good sources of potential antioxidants. Hence, they are added to
food containing unsaturated fatty acids in order to increase shelf life and prevent them from
turning rancid due to oxidation
• With changes in lifestyles, Southeast Asian countries are expected to record an average
increase of 25% in consumer spending by 2020. In line with a growing working population,
there has been a shift in consumer preferences toward ready-to-eat packaged food over
preparing and cooking a meal; with small families preferring single-serve packs. This
demand is expected to drive the volume of flexible packaged food in the market
• Ready-to-eat, frozen, dry, baked, and fresh food together accounts for 60% of the total
flexible packaging food market. As shelf life is accorded the maximum importance, the
extensive use of antioxidants in food products is expected to drive market growth
• This driver will have a medium impact in the short term. However, with population growth
and increasing preference for ready-to-eat food products, the impact of urbanization will be
high in the long term
15The global antioxidants market was valued at $377m in 2016 and is expected to reach
$486 in 2021 which corresponds to a revenue CAGR of 5.2%
Source: Frost & Sullivan
Antioxidants Market: Revenue Forecast, Global, 2013–2021
CAGR, 2016–2021 = 5.2%
0,0
1,0
2,0
3,0
4,0
5,0
6,0
7,0
0,0
100,0
200,0
300,0
400,0
500,0
600,0
2013 2014 2015 2016 2017 2018 2019 2020 2021
Revenue 341,0 351,2 363,1 377,1 393,5 412,2 433,8 458,4 485,7
Growth Rate - 3,0 3,4 3,9 4,4 4,7 5,3 5,7 6,0
Gro
wth
Rate
(%
)
Rev
en
ue (
$ M
illio
n)
Year
16Europe is currently the largest regional market for antioxidants; the simplification of
the product approval process is expected to support their supply
Source: Frost & Sullivan
Antioxidants Market: Percent Revenue
by Region, Global, 2016
Antioxidants Market: Percent Revenue by
Region, Global, 2021
Europe 37,2%
North America34,0%
Asia-Pacific24.4%
ROW4,4%
Europe37,0%
North America35,0%
Asia-Pacific23.5%
ROW4,5%
17From a competitive points of view, multinationals BASF, DSM and ADM dominate but
Milan-headquartered Indena is a notable market participant
Source: Frost & Sullivan
Antioxidants Market: Competitive Structure, Global
Number of Companies in the Market 30 to 40
Competitive Factors Cost-effective and high-efficacy product innovations
Key End-user Groups Food
Major Market Participants
(share in revenue terms)BASF, Germany (16%); DSM, Netherlands (12%); ADM, US (11%)
Market Share of Top 3 Competitors 39%
Other Notable Market Participants
Kemin (US), Kalsec (US), Prinova (US), DuPont-Danisco (Denmark),
Vitae Naturals (Spain), Indena (Italy), Naturex (France), Vitablend
(Netherlands), Cargill (US)
18A continued focus on natural extracts and new delivery & dosage forms is expected to
offer opportunities for established players and challengers
Source: Frost & Sullivan
Novel Fungi-based Antioxidant Derived from Mushroom
• ERGONEINE, a product developed by the French company, Tetrahedron, was approved by EFSA, after a
three-year-long evaluation.
• Mitigating suspicions that rising rates of inflammatory diseases were due to the consumption of the
company’s product, the EFSA declared the novel source as safe to be used in food and supplements
based on studies and evaluation.
• The product is manufactured using a patented synthetic process that involves a reaction of I-hercynine,
bromine and cysteine, and water.
New Delivery Forms of Lutein and Zeaxanthin Antioxidants
• DSM (Netherlands) and Kemin (US) launched new delivery forms of lutein and zeaxanthin, essential
antioxidants for eye health.
• The product OPTISHARP, which contains Zeaxanthin, is offered in powder form and is ideal to be used
in tablets, gummies, and chewable formulations. The other product, FloraGLO-OPTISHARP, is offered as
a suspension targeting soft-gel applications.
• Kemin, the manufacturer of these products, adheres to strict quality guidelines and all processes in the
supply chain, starting from seed cultivation to flower harvesting.
19
...
• TBC
Flavour Delivery Technologies
20Flavour delivery technologies are based on encapsulation, the process by which
active agents are entrapped within the walls of a carrier material
Source: Frost & Sullivan
Outline of the Encapsulation Process
Encapsulation is defined as the process by which active agents are entrapped within the walls of a carrier
material, to form capsules with diameters ranging from a few nanometers to a few millimeters.
Encapsulation helps stabilize active agents, modifies the physical form of unstable compounds to convert them
into solid forms that are easy to handle, and increases the life of the compound being encapsulated.
Active agents can be in the form of solids, liquids, or gases, and they are released from the confines of the
carrier materials under specific conditions at controlled rater over prolonged periods of time.
What is
Encapsulation?
Active Material Carrier Material Encapsulant
• Physical
• Physio-chemical
• Chemical methods
Controlled Release of
Enclosed Agents
Activation Mechanism
Temperature
Pressure
Rubbing
Moisture• Wall rupture/
dissolution
Fragrance and flavor delivery technologies are based on encapsulation processes for effective delivery of active compounds
21Demand is driven by the growing need for slow release, with long lasting flavours key
to the success of products for cooking and/or consumption
Source: Frost & Sullivan
Short Term
(1-2 Years)
Medium Term
(3-4 Years)
Long Term
(5-8 Years)
Demand for Long-lasting Effects
Encapsulation is used to make flavor providing ingredients that are slowly released during the
cooking process or while chewing food products Complex encapsulation processes are used to
make long-lasting fragrances that exhibit the full range of the fragrance’s notes.
Increasing Investments to Enhance Product Capabilities
With companies increasing their research and development (R&D) investments toward enhancing
product capabilities, novel encapsulation technologies are being developed. Process plants, mixing
systems, and handling techniques are becoming more refined.
Preference for Products with Signature Fragrance/Flavor
Consumers gravitate toward products that provide a distinct flavor or fragrance. Unique and natural
raw ingredients, such as vanilla or ylang-ylang, that help achieve this are integrated in a high
performing form into products through novel encapsulation technologies.
Increase in Health Conscious Consumers
Encapsulated flavors that help make healthy food more tasty, and encapsulated fragrances that can
be used in hygiene providing products are some of the key developments made to meet the
growing consumer trend for health and wellness.
Encapsulation of Flavors and Fragrances: Market Drivers, Global, 2017–2025
Impact: High Medium Low
22Market participants are innovating at each stage of the value chain (1/2)
Source: Frost & Sullivan
ZoomEssence
(US)
Innovative Food
Processors
(IFP)
(US)
inprotec
(Germany)
GAT Food
Essentials
(Germany)
Stakeholder Key Developments Significance/Trends Technology Impact, 2017
Low
Low
Low
Low
High
High
High
High
Natural extracts can be converted
into a powder form that provides
enhance flavor experience to
consumers.
The formation of uniform coating
layers around encapsulated flavors
allows the release profile to be
improved.
The encapsulation process allows
compounds to be protected from
incompatible formulations.
Microcapsules can be formed
using natural and non-genetically
modified organisms (GMOs)
ingredients.
Zooming™: The no-heat spray drying process can be used to encapsulate
liquid flavors into a powder form, without affecting the fragrance’s integrity
while enhancing its stability.
Applications: Savory-condiments, snacks, confectionary
PrimeCAP® : These are encapsulated range of food-grade ingredients
made using the company’s patented tangential fluid bed technology.
Uniformly-sized multilayer coatings can be formed using the technology.
Applications: Beverages, savory-condiments, snacks
Matrix encapsulation: Fluid bed coating is used for converting oils and
fine powders into free-flowing granules. The process allows liquid loading
up to 50%, and protects sensitive compounds from oxidation.
Applications: Savory-condiments, detergents
wowCAPS®: The microencapsulation technology helps stabilize oils, oil
suspensions, and water soluble compounds by cross-linking polymers in
the active core ingredient suspension.
Applications: Beverages, dairy
23Market participants are innovating at each stage of the value chain (2/2)
Source: Frost & Sullivan
Givaudan
(Switzerland)
Capsulae
(France)
Clextral
(France)
Etosha Pan
(India)
Stakeholder Key Developments Significance/Trends Technology Impact, 2017
The technology can be used for
developing oral care products
producing different flavors when
chewing.
Encapsulated ingredients in dry
form can be created using the
technology.
The stability and size of the droplets
formed can be appropriately
selected by configuring the
extruder.
The technology allows a
standardized flavor form to be
developed for addition into dry
products.
Toothpaste with Different Encapsulated Flavors: The company has
developed a toothpaste that contains microencapsulated gelatin or starch
grains. Edible plant oils are used as carrier materials.
Applications: Oral care
Prilling: The company has developed spray chilling machinery for
encapsulating active solids or lipophilic liquid in gelled polymer matrix to
form microbeads. The resulting compound has high thermal stability.
Applications: Snacks, savory-condiment
Twin Screw Extrusion (TSE) Process: Aromatic flavors in liquid form are
encapsulated continuously using TSE process. Temperature and screw
shear are appropriately controlled to form stable, small droplets.
Applications: Savory-condiments, snacks, confectionary
Cyclodextrin Complexation: This is a molecular inclusion process for
flavor entrapment. The process allows liquid flavorings to be converted into
a non-hygroscope, powdered flavor form.
Applications: Savory-condiments, snacks, confectionary
Low
Low
Low
Low
High
High
High
High
24In Europe, R&D efforts are focused on developing encapsulation processes that
extend to applications for fragrances in household and skin care
Source: Frost & Sullivan
NA Companies Depend on Partnerships for R&D Purposes
R&D activities by companies are predominantly conducted internally. The companies work along with their clients
throughout the entire product development phase to provide customized encapsulated ingredients. On the other
hand, encapsulation equipment manufacturers form partnerships with companies that have access to R&D facilities
for improvising the ingredients manufactures. R&D projects in the NA region is largely focused on flavor
encapsulation technologies for use in packaged foods.
Europe has Company-sponsored Research Initiatives
Companies such as Giract (Switzerland) are sponsoring university programs on flavor encapsulation research to
facilitate the development of novel encapsulation processes. Such initiatives propagate Europe’s position as the
fastest growing market for encapsulated flavors. Research on fragrance encapsulation technologies is concentrated
on applications in the household care and skin care industries, demonstrating the consumer demand in Europe for
products that provide long-lasting fragrances.
APAC Region has University-led Research Projects
Research activities in Japan focus on the stabilization of exotic flavor ingredients, such a umami and soy sauce, for
use in snacks and savory-condiments. Research projects in APAC, especially in Japan, India, and Singapore, are
conducted by universities and research institutes. These projects are funded by grants from the local government.
Reflecting the region’s preference for subtly-scented fragrances derived from natural ingredients, research on
fragrance encapsulation focuses on encapsulating essential oils derived from ginger, eucalyptus, and citrus.
25CPL Aromas and Agdot in the UK are examples of start-ups which have received
funding to support their research and commercialisation activities
Source: Frost & Sullivan
Funding Collaborative
Research Projects
• In January 2016, the National
Science Foundation (NSF) provided
$150,000 to InnovaNutra Inc. (US)
under the Small Business Innovation
Research (SBIR) project for the
development of natural and low cost
food-derived encapsulation products
with high stability and nutritional
benefits.
• Researchers from Harvard
University (US) and Cornell
University (US) have received
funding from P&G (US) and NSF for
developing long-lasting
encapsulated fragrances using bulk
emulsification processes.
Focus on New
Product
Development
• In February 2016, Aqdot (UK)
raised $6.7 million series A funding
for the commercialization of its
Aqdot™ encapsulation technology
platform. The technology can be
used for controlled delivery of
fragrances in household and
industrial applications.
• In August 2017, CPL Aromas (UK)
launched a new R&D center worth
$1.4 million in Brixworth (UK). The
new R&D facility comes equipped
with an Encapsulation Lab for
creating liquid encapsulated
fragrances that can be used in new
perfume formulations.
Foreign Investments
for R&D Center
Development
• In May 2017, Givaudan (Switzerland)
has invested in the development of a
500 square meter fragrance
encapsulation center in Singapore.
The new center is expected to be in
operation by mid-2018, and is meant
to serve applications in the detergent
and personal care industries.
• Since 2014, CPL Aromas (UK) and
Firmenich SA (Switzerland) have
developed state-of-the-art R&D
facilities in Indonesia. CPL Aroma’s
center focuses on fragrance
encapsulation while Firmenich’s
center focuses on flavor
encapsulation.
NA Europe APACKey Takeaway
• The NSF is a major
contributor for funding
collaborative research
activities by universities in
the US.
• In Europe, funding
initiatives are concentrated
on developing fragrance
encapsulation technologies,
illustrating the region’s
superior market position in
the fragrance industry.
• Funding activities in APAC
is leaning towards setting
up of new R&D facilities
that help companies with
bases in other regions form
collaborations locally-
situated customers.
26Moving forwards, the encapsulation technology roadmap is trending towards greater
customisation and a widening of the application landscape
Source: Frost & Sullivan
20252017 20212019 2023
Thermally stable
encapsulated flavors and
fragrances
Enhancing the thermal stability of encapsulated products is a major challenge faced by the technology end-users. The development of strong carrier material that do not
alter the properties of encapsulated contents would help circumvent this challenge in the short-term. Spinning disk reactor technology, which is highly favored for making
stable multiple emulsions would be adopted in the large-scale over the next 2 years. While freshness inducing encapsulated fragrances are largely used in household
care applications, in future companies would develop odor shield technologies that contain radiant scents for breaking down odor causing oxygen, nitrogen, and sulfur
molecules. By 2025, low-cost, customizable microencapsulated products would be developed using 3D printing techniques. Fiber materials are expected to be used as
wall coatings for stabilizing the flavor or fragrance core ingredients.
Adoption of spinning disc reactor
technology for encapsulating flavor
oils and unstable essential oils
Encapsulated flavor
ingredients for non-food
applications, e.g.
encapsulated citric acid for
breaking down gums in oil
and gas industries.
Development of odor shield
technologies that help control
odor causing gases
Large-scale adopt of nano-
encapsulation techniques
Use of phase change
materials for encapsulating
fragrance oils
Synthesis of nanometer-sized
fragrance encapsulated with chitosan
as a carrier material
3D printed microencapsulated
products
27
...
• TBC
Curcumin Market
28Turmeric is the raw material used in the production of curcumin 95% which finds its
application largely in nutraceuticals (54%) and F&B (34%)
Source: Frost & Sullivan
• Turmeric is the raw material used in the manufacturing of curcumin
95%, a standardized extract of curcuminoids in the form of oleoresins.
Curcumin 95% goes into formulations in the form of capsules and
tablets, and even external use in creams and lotions of herbal,
nutraceutical, dietary supplement, and cosmetic products
• The absorption and bioavailability of curcumin from ingested food is
limited for being effective in specific therapeutic applications.
Additionally, the concentration of curcumin in turmeric is low (2%–6%
by dry weight)
• Very large quantities of turmeric powder would have to be consumed
to result in any direct and significant therapeutic benefits. Thus, the
only logical and medically practical approach is to use a concentrated
extract of curcuminoids or curcumin, the main active constituent in
turmeric
• Curcumin 95% is a turmeric oleoresin extract that is standardized to
contain not less than 95% of the curcuminoids. Standardizing to 100%
curcumin is conceptually attractive, but not practical or justified, due to
highly escalated manufacturing costs
• The bioavailability of curcumin 95% can be reduced by the gastro-
intestinal tract and biochemical factors. Several technical strategies
have been adopted to make curcumin more absorbable and
bioavailable, by different developers and suppliers. Combining with
piperine (from black pepper) and formulating with lecithin
(phospholipids) are two of the popular methods
En
d A
pp
licati
on
s
Nutraceuticals
Food & Beverages
Cosmetics
Others (animal nutrition,
photovoltaics, and textiles)
Others (frozen foods, desserts and salads)
29Curcumin 95% can be safely used in large doses without producing side-effects and is
scientifically proven to prevent diseases and relieve pain
Source: Frost & Sullivan
Curcumin Market: Market Drivers and Restraints, Global
Drivers 1-2 Years 3-4 Years 5th Year
Increasing R&D activity toward curcumin 95% extracts with value-added
propertiesH H H
Growing applications due to lack of undesirable side effects and safety in large
dosesH H M
Scientific evidence for disease prevention and pain relief by curcumin use has
been increasingH M M
Impact Ratings: H = High, M = Medium, L = Low
Restraints 1-2 Years 3-4 Years 5th Year
Confusion among consumers about differences between turmeric and curcumin
hinder the marketH H H
Competition from low-priced extracts threatens standardized curcumin extracts
95%.M M L
Combination with cheaper, synthetic curcumin reduces true volume
consumptionM L L
30Growth is primarily stemming from supply-side innovations; manufacturers are
working to increase absorption by improving delivery mechanisms
Source: Frost & Sullivan
Increasing R&D Activity Toward Curcumin 95% Extracts
• The major driver for the increasing use of curcumin 95% extracts in the global market is the keen R&D of
suppliers to improve its bioavailability profile through various innovative technological strategies.
• Curcumin 95% extract as initially produced tends to be poorly absorbed in the intestines.
• Manufacturers have worked effectively in increasing its absorption and bioavailability after oral intake in the
human gastro-intestinal tract.
• Some of the popular curcumin 95% ingredients have added piperine (from black pepper) e.g., C3
Complex/Sabinsa.
• Phopholipids/liposomes act as curcumin carriers in Meriva/Indena, while cyclodextrin forms a complex
with curcumin in Cavamax W*/Wacker Chemie.
• Other innovative patented solubilization and delivery technologies include the following:
‒ SLCP Technology in Optimized Curcumin/Longvida of Verdure Sciences (US)
‒ UltraSOL Nutrient Delivery in CurcuWin of OmniActive (US)
‒ Polar Non-Polar Sandwich Technology in CureIt of Aurea Labs (India)
31The global curcumin 95% market was valued at $49m in 2016 and is expected to reach
$101 in 2023 which corresponds to a revenue CAGR of 12.6%
Source: Frost & Sullivan
Curcumin Market: Revenue Forecast, Global, 2013–2023 CAGR, 2016–2023 = 12.6%
0,0
2,0
4,0
6,0
8,0
10,0
12,0
14,0
16,0
0,0
20,0
40,0
60,0
80,0
100,0
120,0
2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023
Revenue 32,8 36,0 39,6 43,9 48,8 54,4 61,0 68,7 77,9 88,5 100,8
Growth Rate - 9,6 10,1 10,6 11,2 11,7 12,1 12,6 13,3 13,6 13,9
Gro
wth
Ra
te (
%)
Re
ve
nu
e (
$ M
illi
on
)
Year
Curcumin Market: Revenue Forecast, Global, 2013–2023CAGR, 2016–2023 = 12.6%
32Europe is currently the second largest regional market for curcumin; its growing use
as a therapeutic agent in cancer treatment will boost demand
Source: Frost & Sullivan
Curcumin Market: Percent Revenue
by Region, Global, 2016
Curcumin Market: Percent Revenue by Region,
Global, 2023
North America35,1%
Europe30,1%
APAC24,8%
ROW10,0%
North America35,2%
Europe34,8%
APAC23,6%
ROW6,5%
33From a competitive points of view, curcumin extraction is centred in India but US
players such as Sabinsa offer value-added processing capabilities
Source: Frost & Sullivan
Curcumin Market: Competitive Structure, Global
Number of Companies in the Market More than 20
Competitive FactorsPrice, product quality, enhanced bioavailability, brand strength, customer
service
Key End-user GroupsPrimarily herbal and dietary supplement manufacturers; functional food and
beverage manufacturers, cosmetics manufacturers
Major Market Participants
(share in revenue terms)
Arjuna Natural Extracts, India (33%); Sabinsa, US (30%), OmniActive, US
(12%)
Market Share of Top 3 Competitors 75%
Other Notable Market Participants Verdure Sciences (US), Organica Aromatics (India)
34Players across the supply chain are looking to increase the bioavailability and
improve the effectiveness of curcumin through product development
Source: Frost & Sullivan
Curcumin Market: Value-Add Strategies, GlobalSupplier Curcumin Brand Technologies/ Value-Addition Strategies
Akay (India)/Bioactives American
(US)CurQfen Provides a formulation of curcumin with fenugreek galactomannans as curcuma-galacto-mannosides (CGM)
AQUANOVA (Germany) NovaSOL®The NovaSOL® biomimetic micelle is completely stable through the digestive process, delivering Curcumin to the
intestinal wall for maximum therapeutic effect
Arjuna Natural Extracts (India) BCM-95 Micronized formulation with curcuminoids, essential oils of turmeric and ar-turmerone
Aurea Biolabs (India) Cureit Uses Polar Non-polar Sandwich (PNS) technology and facilitates the smooth penetration of the ingredient into the
intestinal/target tissue's polar non-polar cell walls.
Indena (Italy) Meriva Employs a curcumin-phosphatidylcholine phytosome complex
Konark Herbals & Healthcare
(India)N-Curcusorb/ Nanocurcumin N-Curcusorb is curcumin in nano-particle size as nanoemulsion
OmniActive (US) CurcuWin Applies UltraSOL Nutrient Delivery System; converts lipophilic/ poorly absorbed nutrients to water-dispersible
ingredients for enhanced bioavailability
Sabinsa (US) Curcumin C3 Complex® Curcumin, demethoxycurcumin, and bis-demethoxycurcumin complex with the addition of piperine or Bioperine®
SV Agrofood (India) Liquid Nano Curcumin Nano-encapsulated curcumin in liquid form
Synthite Industries/ (India)/Unibar
(US)CurQnetic
Curcumin 95% with vanillin (from vanilla) and gingerols (from ginger). Vanillin and gingerol act as adjuvants that help
curcumin to bypass the glucuronidation reaction and increase absorption and retention
Theravalues (Japan)/Integrative
Therapeutics (US)
CurcuminRich®
Theracurmin®Fine granulation and suspension technology
Verdure Sciences (US) Longvida Optimized curcumin with patented SLCP™ (Solid Lipid Curcumin Particle Technology) technology
Wacker-Chemie (Germany)Cavamax W8 Curcumin
ComplexUtilizes a cyclodextrin-based curcumin complex technology
35
...
• TBC
Food Safety Technologies
36Primary safety technologies in the dairy food industry are those that are associated
with the prevention, detection, and elimination of contaminants
Source: Frost & Sullivan
Food Safety in Dairy Industry: Technology Objectives and Focus, Global, 2017
Primary technologies are associated with the prevention, detection, and
elimination of contaminants in milk and other diary compounds. This includes
• Physical Separation of Contaminants
• Thermal/non-thermal intervention
• Packaging
• Coatings
• Biosensors
• Automated food processing
• Improve food safety
• Ensure consumer protection
• Boost consumer confidence
• Improve efficiency throughout the supply chain
• Benchmark parameters for food safety management
• Provide an action plan to counter various criticalities
• Production Scheduling
• Verification of Sanitation Effectiveness
• No chemical contamination
• HACCP principles
• Real-time monitoring
Supplementary technologies offer risk assessment that enables food product
suppliers, manufacturers, and consumers to identify the source and the intensity
of contamination, while prohibiting further spread. This consist of
• Technologies with electronic traceability
• Sensors and microelectronics
• Smartphones and mobile applications (Internet of Clean)
• Real-time scanning and monitoring
Primary Technologies Supplementary Technologies
Focus on Prevention, Detection, Elimination Focus on Risk Assessment
Technology Objectives Technology Objectives
37Demand is driven by increasing incidences off foodborne illnesses which, in turn, are
prompting the authorities to introduce new regulations
Source: Frost & Sullivan
Food Safety in Dairy Industry: Drivers, Global, 2017
Foodborne illness concerns driving authorities to promote new regulations
• According to the US Center of Disease Control and Prevention, foodborne illness affects more than
48 million Americans each year, accounting over 100,000 hospitalizations and thousands of deaths.
• The Food Safety Modernization Act (FSMA) presents a new framework of food safety supervision,
calling to the application of the best available science and technology to address this concern.
• It is important to mention that in particular for the dairy industry, the Food and Drug Administration
(FDA) and state regulatory agents have worked closely with dairy farmers and processors during the
past years. This can be exemplified in the federal Pasteurized Milk Ordinance—a set of requirements
for milk production, milk hauling, pasteurization, product safety, equipment sanitation, and labeling,
which has worked efficiently. Indeed, less than 1 percent of foodborne illness outbreaks in the US
involve dairy products.
Beyond hazard analysis and critical control point systems
• The Innovation Center's Food Safety Operating Committee (FSOC) is advancing to a higher level, by
applying, in agreement with the FSMA’s statement more comprehensive food safety supervision
measures, and embracing an education and training program for controlling pathogens within dairy
processing plants. Food safety recalls compromising the reputation of the industry needs to be
avoided by providing processors and suppliers with food safety best practices.
• The program includes training for the entire supply chain, voluntary internal audits within a common
standard to be linked to the Global Food Safety Initiative, and annual exchanges between
government regulators and FSOC executives for continuous improvement.
Short term
Long term
Short term
Long term
High
1
23
4
5
<1 >5
Low
3
High
1
2 4
5
<1 >5
Low
43
Low High
1 5
<1 >5
2
Low
2
High
1 5
<1 >5
34
38Key primary enabling intervention technologies in the dairy food industry include bio-
illumination, plasma, thermal and non-thermal solutions
Source: Frost & Sullivan
Key Enabling Intervention Technologies
Bio-illumination Technology
Molecular pathogen detection
systems are based on isothermal
DNA amplification and ATP
bioluminescence detection
technologies. Bioluminescence
platforms represent rapid and
sensitive detection systems that
combine nanotech and synthetic
biology approaches to detect live
bacterial pathogens in many
environments and sample types. By
combining both technologies,
microorganisms can be detected
before they reach end consumers,
thus re-shaping the food chain from
control to prevention.
Plasma Technologies
Cold plasma is a non-thermal “green”
technology that uses energetic,
reactive gases to inactivate
contaminating microbes on meats,
poultry, fruits, and vegetables,
enhancing microbial food safety and
quality, without compromising the
nutritional, functional, and sensory
characteristics of foods. Bactericidal
molecules (ozone, nitric oxides, and
peroxides) are generated with
minimal power under room-
temperature conditions in seconds to
minutes, with little or no product
heating.
Thermal Technologies
Thermal processing plays a critical
role in keeping food safe from
microbiological contamination, while
remaining high in nutritional and
sensory attributes. Thermal
technologies range from full
sterilization to milder pasteurization
heat treatments. The equipment and
environment used for thermal
processing, including continuous flow
heating and cooling systems, hot-fill
processes, and novel thermal
technologies (microwave, radio-
frequency, and ohmic heating), play
a key role in food safety.
Non-thermal Technologies
Conventional thermal food
preservation has the shortcoming of
possibility of adversely affecting food
quality, organoleptic properties and
nutrients. Non-thermal food safety
technologies have minimal effect on
the nutritional and sensory properties
of foods, while inhibiting or killing
microorganisms in food and
beverages. They comprise ionizing
radiation, pulsed X-ray, ultra-high
pressure, ultrasound, pulsed electro-
magnetic fields, high-voltage arc
discharge, pulsed light, high
hydrostatic pressure, and dense
phase carbon dioxide, among many
others.
39Established and emerging players are innovating across these areas (1/2)
Source: Frost & Sullivan
ATP
Bioluminescence
Synthetic Biology
Bacterial
Bioluminescence
Chemilumine
scence
Engineered
Bacteriophages
• 3M
• Sample6
• Neogen
• Hygiena
• Millipore-
Sigma
• Celsis
• BioLume
• Assure
Controls
• MicroBio
Tests
• LuminUltra
• Biotrack
• NCIMB
Cold plasma
Atmospheric
plasma
Micro Plasma
Nano Pulsed
Plasma
Corona Discharge
• Advanced
Plasma
Solutions
• Phygen
Coatings
• Marshfield
Food
Safety
• Troy
Biologicals
• Plasma
Bionics
• VITO
• Adtec
Ultra High
Pressure
Pascalization/
Bridgmanization
Ionizing Radiation
Dense phase
carbon dioxide
• Hiperbaric
• Diversified
Technologies
• Certified
Laboratories
• Avure
• American
Pasteurization
Company
• Multivac
• Hain BluePrint
Thermal Spraying
Microwaves
Ohmic Heating
Infrared Heating
• Marlen
International
• MMC
• Procedyne
Corp
• Thermal Care
• Unitherm
Food
Systems
• Dimplex
Thermal
Solutions
• BV Thermal
Systems
• Nabertherm
Ultrasound Radio-Frequency
Heating
Bioillumination Plasma Technologies Non-thermal Technologies Thermal Technologies
40Bio-based and electronic packaging as well as protective and anti-microbial coatings
are important weapons in the fight to improve dairy food safety
Key Enabling Packaging Technologies
Bio-based food packaging
materials are elements derived
from renewable sources when
achieving suitable properties
(gas barrier, water vapor
transmittance, thermal and
mechanical behavior,
and so on.)
Corrosion due to extensive
use of high-pressure water and
steam, often in combination
with various corrosive agents,
increases the need for
protective coatings that meet
strict requirements of food
contact standards.
Polymeric edible coatings
incorporating natural nano-
encapsulated antimicrobials
that may be controlled
released through
multilayered nano-laminate
delivery systems in food
systems.
Providing greater
resolution and broader
visibility to the supply
chain, smart labels and
tags using RFID, sensors
and printed electronics,
have become significant
solutions in recent times.
Custom refrigerated
food temperature and
humidity labels coupled
with smart monitoring
solutions to ensure food
quality and safety
across the entire value
chain once packaged.
Nano-encapsulation and
multilayered delivery systems
are powerful tools to enhance
the functionality of edible
coatings, with the incorporation
of natural antimicrobial agents
and controlled release systems.
Active packaging involves
oxidation retardation,
respiratory process hindering,
microbial attack and moisture
infusion prevention, CO2 and
ethylene scavengers, aroma
emitters, time-temperature
sensors, and so on.
Advanced dispersion
adhesives are used for
laminating cardboard, thus
achieving different
features while providing
superior properties and
ideal processing
characteristics.
Intelligent packaging
comprises sensors to monitor
food quality and safety, such
as time and temperature,
integrity, and freshness
indicators. Nanotechnology is
the most powerful tool for the
development of intelligent
packaging.
Bio-based Packaging Protective Coatings Anti-microbial Coatings Electronic Packaging
Eco-friendly Adhesives Indicative Labeling Food-based Coatings Active Packaging Intelligent Packaging
Source: Frost & Sullivan
41Established and emerging players are innovating across these areas (2/2)
Source: Frost & Sullivan
Sustainable
Bioplastics
Modified Starches
CO2-based
Polymers
Regenerated
Cellulose
Microcrystalline
Waxes
• Metabolix
• Natureworks
• Coca-Cola
Company
• Novomer
• National
Starch
• Dannon
• Ecostar
• BASF
• Avebe
Spraying/Dry
Crumb
Application
Coating
Adhesion
Coalescence
Technology
Micro/Nano
Encapsulation
Chemical
/ Thermal
Stabilization
• Cardolite
Corporation
• AkzoNobel
• Jotun
• Phygen
Coatings
• Dampney
Company
• Sigma
• Metal
Coatings
Corp.
• Sika
• Hempel
• NSF
International
Antimicrobial
Films
Layered
Nanocomposites
Antimicrobial
Nanoparticles
Functional
Biomolecules
• BioCote
• Ai2
• Kastus
• Nanograde
• Curza
• HeiQ Materials
• Microbe
Investigations
• Matera
• Exigence
Technologies
• Kane Biotech
Edible Waxes/
Hydrocolloids
Biocomposite
Coatings
Polysaccharide-
based Coatings
Lipid Coatings
• Proinec
• BASF
• Evonik
• ZEON
• Mitsubishi
• Sinoplast
• Royal DSM
• Witton
Chemical
• MonoSol
• Lyle
• Tsukioka
Film
Surface
ModificationProtein-based
Coatings
Bio-based Packaging Protective Coatings Antimicrobial Coatings Food-based Coatings
42Moving forwards, market participants’ ability to interact with innovation developers to
deliver smart safety solutions will be a key success factor
Source: Frost & Sullivan
Food Safety in Dairy Industry: Emerging Innovation Models, Global, 2017
Intelligent Traceability Solutions
On-site Environmental
Monitoring
Farm-to-Table Surveillance
Integrated Testing Services
Micro/ Nanotechnology and Advanced Materials (Smart Packaging,
Biosensors, Barcodes, etc.)
Internet of Clean (Smart Safety
Solutions, Big Data Analytics, Safety
management, etc.)
Life Sciences Testing Kits
(Bioillumination, PCR,
ELISA, etc.)
Engineering (Thermal/Non-
thermal Processing,
Pulsed-Light, etc.)
Innovation Hubs:
Companies, Institutes, Research Centers,
Foundations, Ventures, Legal and Regulatory Bodies, Government
SMART SOLUTIONS FOOD SAFETY ECOSYSTEMTECHNOLOGY SYNERGY
43
...
• TBC
Personal Care Active Ingredients Market
44Personal care products draw on active and inactive ingredients; the former represents
~35% of the market but this is expected to reach ~50% in 2023
Source: Frost & Sullivan
Ac
tive
In
gre
die
nts
Anti-aging
Ingredients
UV Ingredients
Exfoliating
Ingredients
Others
Moisturizing
Ingredients
Moisturizing ingredients maintain the water level in the skin and prevent skin collagen deterioration.
Moisturizers create and maintain a barrier on the skin to retain water, humectants attract water from the
inner skin layers. Glycerol, hyaluronic acid, amino acids and ceramides are some examples of
moisturizing ingredients.
Antimicrobial
Ingredients
Anti-aging ingredients prevent biological aging such as wrinkling and roughness. The anti-aging market
segment mainly comprises the vitamins product range that fulfills anti-oxidative functions. Vitamin A, B3,
C, and E and derivatives are some of the anti-aging ingredients.
UV ingredients are specialty ingredients that reduce the production of melanin, which pigments the skin.
By restricting melanin production, the skin is given a lighter hue, while protecting it from
harmful UV radiation.
Exfoliating ingredients help replace weak skin cells with fresh cells. These are used in facial peel-off
masks, lotions, skin creams, and so on. Glycolic acid and lactic acid are two major types of exfoliating
ingredients.
Antimicrobials inhibit the growth of bacteria on the skin and ensure that body lotions and creams are free
of microorganisms during storage and consumption. The two main types of antimicrobials in the market
are triclosan and triclocarban products.
Other active ingredients included in the study are skin whitening, anti-pollution, and
soothing ingredients.
45Spending on skin, face and body care is closely correlated with GDP growth and
linked to growing awareness of issues such as protection from the sun
Source: Frost & Sullivan
Personal Care Active Ingredients Market: Market Drivers and Restraints, Global
Drivers 1-2 Years 3-4 Years 5th Year
Growing economies H H M
Increasing demand for natural ingredients H H M
Growing awareness leading to an increase in consumer demand H H/M M
Impact Ratings: H = High, M = Medium, L = Low
Restraints 1-2 Years 3-4 Years 5th Year
Increasingly stringent legislation will restrict innovation H H M
A highly price sensitive market will lead to price squeeze,
reducing revenues for manufacturersH M M
Presence of the informal market will negatively impact the market
share for multinational companiesM H H
46Growth in the number of consumers looking to avoid exposure to chemicals is leading
to demand for natural ingredients such as soybeans and neem
Increasing Demand for Natural Ingredients
• Natural ingredients are being demanded by the highly
aware consumers. They hold strong opinions against
personal care products with synthetic ingredients, as they
want to avoid exposure to harsh chemicals.
• Major sources of natural active ingredients are raw
materials such as soybean, neem, fish oil, and aloe vera.
• Preference for natural ingredients is particularly strong
among consumers from China and India, who have been
exposed to traditional Ayurvedic and Chinese medicines
respectively.
• The current share of natural active ingredients in the total
market is 25–30%, which is expected to double to 50–55%.
• The sheer market potential of natural active ingredients is
the reason for most active ingredient manufacturers to
focus on innovation and technology in order to handle the
instability of natural ingredients with other ingredients in the
formulation.
Personal Care Active Ingredients
Market: Natural Ingredients, Global,
2016 and 2023
25-30%
50-55%
2016 2023
Source: Frost & Sullivan
47The global personal care active ingredients market was valued at $3.5b in 2016 and is
expected to reach $5.6b in 2023, a 6.9% revenue CAGR
Source: Frost & Sullivan
Personal Care Active Ingredients Market: Unit Shipment and Revenue Forecast, Global, 2013–2023
Unit Shipment CAGR (2016–2023) = 6.3%; Revenue CAGR (2016–2023) = 6.9%
0,0
100,0
200,0
300,0
400,0
500,0
600,0
700,0
0,0
1.000,0
2.000,0
3.000,0
4.000,0
5.000,0
6.000,0
2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023
Revenue 2.850,3 3.116,6 3.336,0 3.528,7 3.801,6 4.072,8 4.323,2 4.641,9 5.008,2 5.398,5 5.627,6
Unit Shipment 313,4 340,7 365,7 384,0 408,9 432,0 458,4 491,6 523,7 557,8 589,5
Re
ve
nu
e (
$ M
illi
on
)
Year
Un
its
(Kilo
To
ns)
48Growth in Europe is stable at a CAGR of 4.0% (2016-23); this will stem from the launch
of new ingredients as local players “look east” for opportunities
Source: Frost & Sullivan
Personal Care Active Ingredients Market:
Percent Revenue by Region, Global, 2016
Personal Care Active Ingredients Market:
Percent Revenue by Region, Global, 2023
Europe35,4%
Asia Pacific32,4%
North America25,0%
Rest of World7,1%
Europe30,6%
Asia Pacific38,8%
North America21,4%
Rest of World9,2%
49From a competitive points of view, the market is relatively fragmented with 250+
players behind the top three multinationals; BASF, Dow and Croda
Source: Frost & Sullivan
Personal Care Active Ingredients Market: Competitive Structure, Global
Number of Companies in the Market 250+ players with revenue greater than $0.5 million
Competitive Factors Price, product performance, brand reliability, and innovation
Key End-user Groups Personal care products and cosmetic manufacturers
Major Market Participants
(share in revenue terms)BASF, Germany (14%); Dow Corning, US (12%); Croda (10%), UK
Market Share of Top 3 Competitors 36%
Other Notable Market Participants
Ashland (US), Evonik (Germany), AkzoNobel (Netherlands), Lonza
(Switzerland), Lipotec (Spain), SEPPIC (France), Symrise (Germany), and
DSM (Netherlands)
50Technology has enabled the development of new beauty tools such as mobile apps
that improve the efficacy/functionality of personal care products
Source: Frost & Sullivan
Technology Trends
• For the end consumers, technology will boost additional consumption of personal care products. Technology has enabled the
development of new beauty tools such as mobile apps that improve the efficacy and functionality of the beauty routine. These apps
and tests provide customization to end consumers.
‒ GeneU (UK) and SKINSHIFT, Austin, Texas (US) sell DNA tests that analyze the skin and suggest a combination drawn from an
available pool of serums and nutritional supplements.
‒ Romy Paris’ (France) Figure “beauty assistant” blends encapsulated active ingredients into a serum or cream for the skin’s
specific needs, determined by a smartphone app.
‒ Feelunique (UK), a mobile make-up app, allows consumers to virtually try on products in different shades across brands. The
app uses face recognition technology.
• Another example of technological advances is the proliferation of digital media among consumers. Online retailing and social media
advertising has recorded a CAGR of 20% during 2010−2015, being expected to record a robust CAGR of 12−15% during
2016−2023. The Internet has created several platforms for the consumer to be more aware of product ingredients. To take
advantage of this social phenomenon, most of the cosmetic companies, especially the new entrants, are advertising their personal
care products on social platforms. Social media has also led to a rise in consumer activism, which is affecting the brands.
• Online Retailing: Another technology platform that has increased the sales of personal care products is Online retailing. This sales
model ensures easy purchase of personal care products for consumers.
51
...
• TBC
Antimicrobial Technologies
52Antimicrobial technologies are used to increase microbial resistance in
conventional (e.g. healthcare) and increasingly emerging areas (e.g. fabrics)
Source: Frost & Sullivan
Summary of Key Antimicrobial Technologies, Global, 2017
Peptidomimetic systems with antimicrobial
functions are being increasingly used for coating
applications.
Polymeric antimicrobials comprise
polycarbonates, polyurethane,
polyphosphoester, polyvinylpyrrolidone, and
several other polymers that are used as
additives or antimicrobial coating formulations.
Phenolics comprise the use of one or more of
compounds such as triclosan, chloroxylenol, and
phenol for antimicrobial formulations. Derivatives
such as butylated hydroxytoluene (BHT) are used
as food additives in small amounts.
Quarternary ammonium compounds encompass
one or more of benzalkonium, octenidine,
cetylpyridinium, and other compounds that are
frequently used as antimicrobial additives and
disinfectant formulations.
Antimicrobial Polymers Antimicrobial Peptides Phenol and Derivatives
Quaternary Ammonium
Key Antimicrobial Platforms
Image Source: Frost & Sullivan
Natural antimicrobials components comprise
active ingredients derived from natural
substances such as honey and turmeric. The
compounds are often used as food additives
Natural Antimicrobials
Other compounds such as nitrofurans, acridines,
hydrogen peroxide, and polymeric metals are also
emerging as potent antimicrobials.
Metal ions such as silver, copper, selenium,
and zinc are frequently used in antimicrobial
coating formulations.
These antimicrobials encompass chlorhexidine,
hexamidine, polihexanide, propamidine,
dibrompropamidine, and other related
compounds, which are frequently used in coating
formulations.
Biguanides and Amidines Metallic Ions Others
53Growth is driven by ongoing concern about the level of healthcare-associated
infection and the use of new antimicrobial platforms to address this
Source: Frost & Sullivan
Healthcare-associated infection (HAI) continues to be a significant global concern, hence
there is growing research for developing new antimicrobial platforms that can
significantly decrease the risk of microbial infections
There is a growing use of polymeric and metallic antimicrobial platforms for reducing
infections across diverse healthcare settings, especially for medical device coating
applications.
Increasing consumer awareness about natural ingredients and growing needs to address
adverse events that result from the use of harsh antimicrobials have fuelled the
development of natural antimicrobials.
54Metallic ions are emerging antimicrobial agents with elements such as silver, copper
and selenium often used in antimicrobial coating formulations
Source: Frost & Sullivan
Overview
Chelating metal ions are potent
antimicrobial agents. This
technology platform usually
includes the use of one or more
compounds of silver, copper,
zinc, gold, palladium, titanium,
and selenium. Silver and copper
constitute some of the frequently
used metallic ions for
antimicrobial applications.
Mechanism of Action
Silver functions by interacting
with thiol groups within
microbial proteins and enzymes
present in cell membrane. The
interaction leads to the release
of potassium ions, which may
subsequently cause membrane
damage microorganisms.
Copper ions are known to
damage bacterial membrane
proteins and induce hydroxyl
radical formation, which
eventually leads to membrane
damage, oxidative
stress, and cell death.
Metallic Ions
Source: Frost & Sullivan
55Companies are developing uses for metallic ions across application areas such as
F&B, medical devices, personal care/hygiene and construction
Technology Capability
Advantages
• Metals inorganic salts easily dissociate to
release bioactive metal ions, but tend to
be more toxic and less stable when
compared to their organic counterparts,
such as sulfonamides containing
ferrocene
• Effective against a broad spectrum of
microorganisms such as bacteria, fungi,
and viruses
Disadvantages
• Growing microbial resistance
mechanisms inhibit the antimicrobial
functions, For instance, frequent use of
silver has enabled the development of
resistance mechanisms in Salmonella
species
• Organic metal salts and metallic polymers
do not dissociate easily in microbial
environment, hence may be less effective
compared to inorganic salts.
Application Areas
Industry Segment Application Areas
Medical Devices
Catheters, Implants, Endoscopes, Touch
Surfaces in Hospital and Healthcare
Settings
F&B Industry Food Grade Metal Coatings
Personal Care & Hygiene Handwash, Soaps
Industrial, Building & Construction HVAC, Metal Cladding, Paints
Key
Companies
BASF SE, Germany
Bactiguard SE, Sweden
Microban, US
Sciessent, US
Microbecide, Singapore
PolyOne Corporation, US
DSM, Netherlands
BioCote, England
Dow Chemical Company, US
University of Sheffield, UK
Source: Frost & Sullivan
56Bactiguard, in Sweden, is an example of a market participant which is deploying silver,
gold and palladium based coatings for urinary catheters
Stakeholder Application Area Key Technology
Speciality
Coating Systems,
US
Cardiac implants
The company offers the SCS microRESIST™ Antimicrobial Parylene Technology that
comprises vaporized coating and polymerization to enable vacuum deposition of parylene
on devices. The company’s antimicrobial parylene technology enables the unique
combination of biocompatbility with microbicidal functions for a wider application range.
Bactiguard SE,
SwedenUrinary catheters
The company has incorporated 3 metallic components (silver, gold, palladium) in its
Bactiguard Infection Protection (BIP) technology. This coating is applied to the BIP foley
catheter to impart antimicrobial properties. The efficacy of the coating lasts for 90 days. As
the technology platform incorporates three metallic components, the technology offers
enhanced antimicrobial functions.
Gelest Inc., US F&B industry
The company offers BIOSAFE antimicrobial technology that uses a silicon-based
polymer that offers unique non-leaching benefits. The company is pursuing food contact
approval from the US FDA.
BioCote, UK Healthcare
The company offers a wide range of BioCote® Antimicrobial Additives that include
silver, zinc, copper, phenolic, quaternary ammonium, and thiabendazole antimicorbial
additives for coating for several applications. The wide range of active ingredients enable
increased applicability across different industry sectors.
57In Europe, R&D efforts are focused on new novel packaging techniques such as the
use of nanocomposites in cosmetics and wound dressings
1
2
3
Funding
Scenario
Most research projects across Europe focus
toward the use of novel antimicrobial
technologies, such as nanocomposites, for
cosmetic packaging, medical device coating
and wound dressing applications.
Research
Trends
The European Commission has funded a
total of USD 31298061 approximately in
projects related to antimicrobial coating
technologies during the 2015-2016 period.
Emerging
Technologies
European countries, such as Italy and
Poland, are researching to leverage natural
antimicrobials, such, as essential oils, for
preserving cosmetics. Scientists in Spain
and UK are studying to use metallic
antimicrobial coatings to develop
multifunctional bone implants.
Summary of Key R&D Trends, Europe, 2017
Rising focus toward novel
packaging techniques and
growing need to enhance
hygiene are likely to drive new
innovations in this space.
58Moving forwards, the space will be shaped by a reduction in the use of toxic
compounds (e.g. nitrofurans) and a focus on biocompatible antimicrobials
Availability of new antimicrobial
formulations that leverage the use
of multiple antimicrobial
technologies for a wide range of
healthcare & industrial applications
Significantly reduced/negligible
usage of toxic antimicrobial
compounds such as nitrofurans
across the globe and growing use
of biocompatible antimicrobials.
Increasing use and availability of enhanced
peptide-based antimicrobial platforms
across healthcare, industrial, personal care,
and F&B settings.
Increasing focus on the development
and adoption of natural antimicrobial
technology platforms, especially
across cosmetic and skincare
applications.
2019-2022
2023-2026
2027-2030
2015-2018
Source: Frost & Sullivan
59
...
• TBC
Prebiotic Ingredients Market
60Prebiotics for human nutrition include a range of substances of which GOS (54%) and
Fructans (insulin and FOS) are the key revenue contributors
Source: Frost & Sullivan
Prebiotics• “A selectively fermented ingredient that allows specific changes, both in the composition and/or activity in the gastro intes tinal microflora that
confers benefits upon host well being and health” (Roberfoid, 2007)
FructansInulin and
Fructo-oligosaccharide
• Generally carbohydrates containing fructose
• Two of the most widely used prebiotics, having been existent in the market for many years
• Similar structure; however, inulin is a large molecule with a degree of polymerisation (DP) between 11 and 65, FOS comprises smaller
molecules with a DP ranging from 2 to 10.
• Inulin extracted from chicory root and FOS from tranfructosylation from sucrose or hydrolysis of chicory
Xylo-oligosaccharide
• Made up of beta (1-4) linked xylose
• Mainly manufactured by the enzymic hydrolysis of xylan
• Has a DP ranging from 2–6
• Sugar oligomers (xylose units) found in corncob, bamboo shoots, fruits, vegetables, milk, honey
• XOS has both GRAS status and an NDI with the USFDA
Soy-oligosaccharide
• Made up of a mixture of raffinose and stachyhose
• Gotten out of soybean whey
• Has a DP ranging from 3–4
Galacto-oligosaccharide
• Composed of 85% oligo-galactose and some glucose and lactose
• Produced from lactose by beta-galactosidase
• Has DP that ranges from 2–55
• Oligosaccharides resembling GOS occur naturally in human milk and may be one of the factors that protect human infants from gastrointestinal
pathogenic bacteria (Leena Niittynen, et al, 2007)
Isomalto-oligosaccharide
• Glucose oligomers, with α-D-(1,6)-linkages which are not easily hydrolysed and exhibit a digestion-resistant property,
therefore, partially digest in the upper gastrointestinal tract
61Prebiotics help adult consumers to make up their recommended daily levels of fibre
and are finding further applications in infant nutrition products
Source: Frost & Sullivan
Prebiotic Ingredients Market: Market Drivers and Restraints, Global
Drivers 1-2 Years 3-4 Years 5th Year
Consumer trends in the F&B market - clean and clear label,
reduced sugar, and reduced fatH H H
Closing the fibre gap and complementary demand support due to
the strong demand for probioticsM H H
Increasing R&D and awareness of nutritional benefits of prebiotics M M H
Restraints 1-2 Years 3-4 Years 5th Year
Increasing competition M M H
Legislation and lack of official definition/ recommendation of
prebioticsM M M
Natural ingredients subject to price volatility L L L
Impact Ratings: H = High, M = Medium, L = Low
62They are increasingly recognised for more than just their digestive health
functions with manufacturers marketing them as e.g. sugar replacements
Source: Frost & Sullivan
Consumer Trends in the Food and Beverage Market—Clean and Clear Label, Reduced
Sugar, and Reduced Fat
Many food and beverage manufacturers are already responding to consumers’ increasing
demand for foods with clean labels, and reduced sugar and fat. The average food and
beverage consumer defines clean labelling as containing natural/no artificial ingredient.
Prebiotics are now marketed beyond digestive health and functions, include:
• Sugar and fat replacement
• Weight management
• Increasing mineral absorption
• Supporting immune health
• Improving taste and texture
All these means that the prebiotics ingredient market can reach a wider audience as the
ingredients have more benefits and consumers continue to consume food for various
reasons.
These trends will support revenue growth in the prebiotic ingredients market as they are
primarily from natural sources.
Therefore, the future of this market will be highly dependent on consumer trends.
63The global prebiotic ingredients market was valued at $1.5b in 2016 and is expected to
reach $1.8b in 2021, a revenue CAGR of 5.4%
Source: Frost & Sullivan
Prebiotic Ingredients Market: Revenue Forecast, Global, 2016–2021 CAGR, 2016–2021 = 5.4%
3,5
4,0
4,5
5,0
5,5
6,0
6,5
0,0200,0400,0600,0800,0
1.000,01.200,01.400,01.600,01.800,02.000,0
2016 2017 2018 2019 2020 2021
Revenue ($ M) 1.354,5 1.427,7 1.506,6 1.588,4 1.673,0 1.758,4
Growth Rate (%) 5,6 5,4 5,5 5,4 5,3 5,1
Gro
wth
Rate
(%
)
Reve
nu
e (
$ M
illi
on
)
Year
64Demand for prebiotic ingredients is highest in APAC as the region seeks high quality
ingredients in infant milk, following a series of safety issues
Source: Frost & Sullivan
Prebiotic Ingredients Market: Per Cent
Revenue Breakdown by Region, Global, 2016
Prebiotic Ingredients Market: Per Cent
Revenue Breakdown by Region, Global, 2021
North America27.1%
Europe19,7%China
19,2%
Rest of World18,1%
Rest of Asia
15,9%North
America26,2%
Europe19,2%
China19,9%
Rest of World18,3%
Rest of Asia
16.4%
65From a competitive points of view, the players tend to specialise, with Royal Friesland
a leader in the GOS category and Beno a producer of fructans
Source: Frost & Sullivan
Prebiotic Ingredients Market: Competitive Structure, Global
Number of Companies in the MarketThere are approximately 40–50 manufacturers and primary suppliers in the global prebiotic
ingredients market.
Competitive Factors Cost, Quality, Investment in Research, Long standing supplier/customer relationship
Key End-user GroupsVarious food and beverage manufacturers including infant nutrition, Dietary Supplements
manufacturers
Major Market Participants
GOS – Royal Friesland Campina (Netherlands), Ingredion (US), Nissin Sugar (Japan), Yakult
(Japan), Promovita Ingredients/Dairy Crest (UK)
Fructans – Beneo (Germany), Sensus (US), Cosucra (Belgium)
XOS – Futaste (China), Ningbo J&S Botanics (China)
Other Notable Market Participants
ADM (US), CBH Qingdao (China), Ciranda (US), DuPont (US), Fenchem (China), Kitozyme
(Belgium), New Francisco Biotechnology Corporation (China), Nexira (France), Olygose
(France), Solabia Nutrition (France), Tate & Lyle (UK), Sabinsa (US), A&Z Food Additives
(China), Shanghai Freemen (US), Novagreen (US)
66Kitozyme, Prenexus and Olygose are innovate companies which could offer
partnership opportunities for the more established prebiotic suppliers
Source: Frost & Sullivan
Company Overview
Kitozyme (Belgium)
• Manufacturer of medical devices, food supplements, and wine treatment ingredients from non-animal chitosan and
chitin-glucan
• Product details: KiOtransine® is a novel prebiotic fibre made from fungi. The company recently published a study
that shows its prebiotic activity.
• The company already markets three digestive health products based on this technology.
• It also manufactures for private labels and is authorised to sell its products through out the EU-28.
• It is currently open to distribution partners across Europe.
Prenexus Health (US)
• Focuses on the production of natural prebiotic ingredients and cane-derived bioactive compounds in order to promote
health and wellness
• Product details: XOS95™ is currently going through the GRAS approval process and a rigorous clinical trial. It can
be used in food, beverages, and nutraceuticals.
• Non-GMO, organic, and the only solvent used in extraction is water
• Currently focused in North America; grown and manufactured in the US
Olygose (France)
• Develops and produces innovative ingredients from vegetable origin
• Product details: CRAVINGZ’GONE® and AlphaGOS® are alpha-galacto-oligosaccharides made from peas. Simply
put, these are soluble pea fibres.
• Apart from its prebiotic property, CRAVINGZ’GONE® is marketed for weight management, while AlphaGOS® is
marketed for sugar reduction.
• The company also manufactures P-GOS, which is a unique plant-based GOS for infant nutrition.
• According to the company, its products are used in markets such as infant nutrition, baby foods, and dietary and meal
replacements.
67
...
• TBC
Probiotic Ingredients Market
68Probiotic cultures are living microbial organisms which, when administered, benefit
the host by improving his or her intestinal microbial balance
Source: Frost & Sullivan
• Probiotics are defined as live microorganisms which, when administered in adequate amounts, confer a health benefit on
the host.
• The main probiotic ingredients include Lactobacilli, Bifidobacteria, E. Faecium, Live yeast, Bacillus
• The target end applications are;
• Functional Food and Beverage: The majority of food and beverage products that include probiotic ingredients are dairy-
based products such as fermented (sour) milks and yoghurts. Many of these products inherently contain probiotic strains,
and/or have different strains that are commonly blended together to enhance efficacy. Non-dairy food and beverage
probiotic products are also included in this segment.
• Dietary Supplements: These are products that are orally ingested and contain nutrients or other dietary components
meant to supplement the diet. These come in many forms, including tablets, capsules, liquids, and powders.
• Other Human Nutrition: This segment mainly includes infant formulations, which are nutritional food products used in
place and/or in conjunction with human breast milk, for feeding babies and toddlers and are made from a mixture of dairy
products and other ingredients. The segment also includes other clinical nutrition products such as medical foods.
• Animal Feed: Feed additives that are ingredients added to animal feed to improve quality as well as boost animal health
and performance. Probiotics for animal feed are living bacteria that keep the animal’s colon healthy by protecting it from
harmful bacteria and providing overall health benefits.
69Digestive health lies at the core of “health & wellness” for many consumers and is one
of the principle reason why they opt for functional foods
Source: Frost & Sullivan
Health and Wellness
• Health and wellness is now a
mainstream trend in the food and
beverage industry. The health
benefits of probiotics will, therefore,
increase both demand and market
growth.
• Furthermore, digestive health
remains a top reason for consumers
choosing functional foods.
More Research into
Additional Benefits
• There is now significant scientific
evidence to show that the benefit of
probiotics extends beyond digestive
health. Consumers are more willing
to consume products that have
multiple health benefits, as they are
perceived to be cost effective, since
payment is made for more benefits.
• Additional benefits cover weight
management, immune health and,
skin care.
Increased Use in Non-
traditional Segments
• The demand for probiotics now
goes beyond dairy and dietary
supplements. Demand from the
animal nutrition industry,
particularly for use in pet food, is
expected to increase.
Furthermore, the quest for organic
and natural ingredients in
personal care will support the
uptake of probiotics by this
segment.
70In addition, the pet food, personal care and household product segments are
expanding their use of, and therefore driving demand for, probiotics
Source: Frost & Sullivan
• The probiotic ingredient market is demand driven and is expected to continue growing due to increased demand from various sectors. The
more traditional food and dietary supplements markets will continue to dominate. However, markets like the pet food and personal care
markets are gaining traction.
• For the pet food market in particular, market drivers include:
− Owners are becoming more concerned about their pets’ health and wellness, and they are paying increasing attention to the nutritional
values and benefits of pet foods. Extending the lifespan of pets and maintaining their health are the main drivers in the uptake of
probiotics. Pet owners are looking for high quality ingredients and manufacturing standards that are similar to those of human food
ingredients.
− Holistic veterinary medicine has been using probiotics for some time, even as traditional veterinary practices have been reluctant to
embrace this concept, until recently. More research on how pets may benefit from probiotics in recent years has started to change
opinions in traditional veterinary medicine and the use of probiotics is on the rise. Noted benefits include a better immune system
• Personal care and household products are also seen to be expanding their use of probiotics. Probiotics are now added to lotions and
deodorants to fight harmful bacteria.
− The number of personal care probiotic patents published from 2005 to 2015 increased by three times, indicative of the spurt in
innovations in the industry. The United States Patent and Trademark Office has filed the largest number of patents, with Nestec (Nestlé,
Switzerland) and L'Oréal (France) being the top patent owners
− For household products, the number of patents published from 2010 to 2015 increased by 83.6%. The largest number of patents was
filed in the United States, followed by the World Intellectual Property Organization (WIPO), Australia, and the European Patent Office
Probiotics Market: Ingredient Revenue Forecast, Global, 2016–2021
Revenue CAGR, 6.8%
71The global probiotics market was valued at $1.3b in 2016 and is expected to reach
$1.8b in 2021 which corresponds to a revenue CAGR of 6.8%
Source: Frost & Sullivan
0,0
1,0
2,0
3,0
4,0
5,0
6,0
7,0
8,0
9,0
0,0
200,0
400,0
600,0
800,0
1.000,0
1.200,0
1.400,0
1.600,0
1.800,0
2.000,0
2016 2017 2018 2019 2020 2021
Revenue 1.311 1.411 1.509 1.597 1.702 1.820
Growth Rate 7,6 7,0 5,9 6,5 7,0
Gro
wth
Rate
(%
)
Re
ve
nu
e (
€ M
illi
on
)
Year
Probiotics Market: Ingredient Percent Revenue by End
Application, Global, 2021
Probiotics Market: Ingredient Percent Revenue by End
Application, Global, 2016
72Functional Foods & Beverages will remain the main application areas
Source: Frost & Sullivan
Functional Food and Beverage
57.7%
Dietary Supplements
28.5%
Other Human Nutrition*
2.5%
Animal Feed11.3%
Functional Food and Beverage
60.4%
Dietary Supplements
25.8%
Other Human Nutrition*
2.6%
Animal Feed11.2%
73From a competitive point of view, there is a separation between ingredient and
product players with limited vertical integration e.g. Chr Hansen
Source: Frost & Sullivan
Probiotic Product Manufacturers:Human and Animal Nutrition
Probiotic Ingredient Manufacturers
Brand Owners
Retailed Products On-the-shelf or on-line
1
2
3
Probiotic Ingredient ManufacturersBioiberica (Spain), Canbiocin (Canada), Candioli (Italy), Cerbios
Pharma (Switzerland), Chevita (Germany), Chr Hansen (Denmark),,
Danin International (US), Deerland Enzymes (US), Dupont (US),
Ganeden (US), Lallemand (Canada), Lesaffre (France), Novus (US),
Probioferm (US), Probi (Singapore), Probiotical (Italy), Protexin (UK),
Pure Cultures (US), Sabinsa (US), Vets Plus (US)
Key Companies
Product Manufacturers and Brand Owners21st Century® HealthCare (US), Bayer Animal Health (Germany),
Bifodan (Denmark), Biocare Copenhagen (Denmark), Bioiberica
(Spain), Biogaia (Sweden), Candioli (Italy), Chevita (Germany), Chr
Hansen (Denmark), Daflorn (Bulgaria), Danone (France), Deerland
Enzymes (US), Food Science Corporation (US), NaturVet (US), Nestlé
(Switzerland), NOW Foods (US), Nutramax Laboratories (US),
Nutrascience Labs (US), Nutri-Vet (US), Nusentia (US), NWC
Naturals (US), Protexin (UK), Vesale Pharma (Belgium), Versele-
Laga (Belgium), Vets Plus (US), Vital Planet (US), Yakult (Japan)
1
2 3
Distributors
Supply Chain
Vertical IntegrationKey:
Probiotics Market: Value Chain, Global, 2016
Distributors
74Developments in, for example, microencapsulation, stability and controlled release
technologies are driving the market from the supply side
Source: Frost & Sullivan
Heat and pH Stability: According to a scientific study by the University of Nebraska, ProDURA® by Nebraska Cultures was able to demonstrate
superior heat resistance compared to other strains of Bacillus coagulants on the market; hence, it is ideal for food processing applications. The strain’s
protective coating works only under optimum heat, pH, and moisture of the large intestine. It is a powerful shield for the probiotics to withstand extreme
conditions and manufacturing activities. The potency of the probiotic can be maintained for up to 3 years at room temperatures. A further benefit is that
it is scientifically proven to reduce total cholesterol and LDL levels and raise HDL levels in the blood. This supports weight management, which is one
of the top reasons consumers choose food.
Microencapsulation: Vésale Pharma, a Belgian company, has developed a new technology platform for microencapsulation of probiotics called
intelicaps. The innovation gives better protection, prolongs the probiotics’ viability in most presentation forms and enables easy food ingredient
combinations, even under extreme conditions. The technology uses a gentle extrusion method and a proprietary biopolymers blend as shell substrate.
Controlled Release Technology: Controlled release technology is very beneficial in the probiotics market as it improves nutrient availability, lowers
the chances of side effects, heightens product effectiveness, simplifies dosing and improves dosage compliance. BIO-tract®, Nutraceutix ( a brand of
Probi) protects the probiotics from gastric acid, while providing optimal release in the digestive tract. This technology provides a reliable and less
expensive controlled release solution to address a long standing challenge faced by the nutraceutical industry.
Optimised Probiotic Production: SynbioTech Inc.’s SYNTEK® is a probiotics optimising development system that designs the medium, incubation
conditions and coating materials for producing probiotics using its coating and freeze-drying technologies. The survival rate of powdered freeze-dried
probiotics is higher compared to other drying techniques. The high viability of dried probiotics is vital for the health-promoting effects of nutraceuticals.
75
...
• TBC
Urban Farming Innovations
76Urban farms utilise unused land and space to generate an abundance of food in urban
areas and also to create awareness about healthy living
Source: Frost & Sullivan
Urban Farming
Commercial Urban Farming
Vertical Farming
Aeroponics Hydroponics Aquaponics
Greenhouse Farming
Personal Urban Farming
Container Gardening
Raised Bed Gardening
Urban Farming integrates several agricultural practices like animal husbandry, aquaculture, agroforestry and horticulture in a single system and also involves the
utilization of fewer resources as compared to traditional farming practices. Urban farming will be an important practice in heavily populated areas and also provides
access to more freshly produced local produce which reaches the consumers very quickly. This readily available access to locally cultivated produce by following
practices like vertical farming, green house farming, container and raised bed gardening eliminates the need for transporting food over long distances and also
maintains the nutritional value of the product. Urban farms can also be built for educational and training purposes apart from the profit point of view but urban farms in
the future must also make deep inroads into communities which lack access to fresh foods due to lack of funds. The social benefits associated with urban agricultural
practices includes improved health and nutrition along with enhanced food security to the consumers.
Classification in Urban Farming, Global, 2017-2023
77Urban farming is expected to help meet the nutritional requirements of a rapidly
growing population and to address concerns about food security
Source: Frost & Sullivan
Certain types of crops tend to grow faster and healthier in certain regions of the world. This is due to
various reasons, such as the differences in soil, season patterns, rainfall, and temperatures. Owing to this,
generally crops are transported to regions with unavailability using different means of transport. With
increasing fuel prices, the cost of the vegetables and fruits drastically increase. This critical situation has
led farmers to devise methods and apparatuses that enable localized production of various crops that
reduce the logistics cost and other shortcomings of traditional farming practices.
According to the United Nations, The world urban population which stands at 3.968 billion is expected to
grow upto 6.419 billion by 2050. The nutritional requirements of the massive population will increase the
demand for healthy vegetables and fruits. Urban farming can meet the demands by providing opportunities
to produce food locally according to the needs of the user’s diet. It also reduces the need for refrigeration
and storage facilities and the time and distance from farm to plate.
• Freshness of the produce• Automation-enabled farming • Enables local growing and local distribution• Controlled environment that aids in year-round cultivation• Reduced consumption of resources• Higher yields and reduced impact on the environment in comparison with traditional farming practices
Need
Background
Benefits
78Vertical farming is one of the main commercial urban farming solutions
Source: Frost & Sullivan
Vertical Farming
Future Prospects
Implementation of appropriate future
technologies associated with greenhouses
including autonomous systems and utilization
of renewable energy will result in high return
on investment and will also enable optimum
use of natural resources to obtain high yield
per acre inside the greenhouse. These
factors also increase the quality and longevity
of the crops cultivated in the greenhouse.
Gravity Fed Aeroponics for Tubers
Utilization of gravity fed aeroponic systems to cultivate seed yams. The
gravity fed systems do not depend on energy for continuous production.
The seed multiplication ratio of yams is improved using aeroponics.
Potato cultivation in the tropics
High-quality potato production using aeroponics which is based on the
influence of electrical conductivity of the nutrient solution. This system
enables growth of potatoes even in tropical climates.
Automatic aeroponic systems
Digitization of sensors for precise measurement of temperature and the
level of nutrients in solutions, pH, and electrical conductivity in aeroponic
systems, which prevent irrigation malfunctions and increase crop yields.
Customizable Aeroponic Module
Aeroponic cultivation with integrated misting systems consisting of fine
mist nutrients available directly to the roots in a scalable and customizable
module.
79NASA is leading innovations in vertical farming, conducting experiments on the ISS to
enhance cultivation of crops with no soil and less water
Source: Frost & Sullivan
National Aeronautics and Space Administration (NASA) has conducted several experiments in the International Space Station
(ISS) to enhance cultivation of crops in space with no soil and less water. NASA has partnered with Agrihouse (US), Aerogrow
International (US), and North Carolina State University to achieve advancements in the growth of foods in space. Aerogrow
International’s seed pod technology was the best suited on the ISS to grow lettuce, vegetables, herbs, and indoor flowers.
The National Horticulture Board set up by the Government of India provides assistance for the establishment of futuristic
production units based on aeroponics. Various organizations are eligible for this assistance from the Indian Government if it
practices open cultivation in 4 hectares or for 1000 square feet in a protected environment. Hi-tech equipment including
precision farming, smart irrigation, and fertigation systems will be provided under the Production and Post Harvest Management
of Horticulture Crops program.
Vertical Farming
1The Yam Improvement for Income and Food Security in West Africa (YIIFSWA) will utilize aeroponic systems to transform yam
cultivation in Ghana and Nigeria. This program will also aid small-scale farmers in West Africa to produce high-quality yam with
improved income and food security. This program is also financed by the Bill and Melinda Gates Foundation and the
Governments of Ghana and Nigeria. This project will improve the lives of 1.6 million people in West Africa who are dependent on
the yam value chain. Soil less aeroponic systems were utilized to eliminate several soil borne diseases associated with yam
production in West Africa.
2
3
80Greenhouse farming is one of the main commercial urban farming solutions
Source: Frost & Sullivan
Greenhouse Farming
Future Prospects
Implementation of appropriate future
technologies associated with greenhouses
including autonomous systems and utilization
of renewable energy will result in high return
on investment and will also enable optimum
use of natural resources to obtain high yield
per acre inside the greenhouse. These
factors also increase the quality and longevity
of the crops cultivated in the greenhouse.
Geothermal Energy based Heating Systems
Renewable energy synthesized from geothermal sources are known as
ground source heat pump systems (GSHP). These heating systems are
less expensive in terms of conventional fossil fuel heating systems and
also reduce OPEX.
Bionanocomposites
Utilization of Bionanocomposites as a growing medium provides prolonged
bacterial resistance to the crops and also increases the yield and shelf life
of the crops in greenhouses.
Automation of Greenhouses
Wireless communications and sensing technologies will enable the
monitoring of the environment inside the greenhouse. This ensures optimal
environmental conditions which will increase the yield of crops.
Unmanned Ground Vehicles
Monitoring of the environmental variables like soil, moisture, and
temperature will be facilitated by the use of unmanned ground robots.
81The US Forest Service has collaborated with the State of Alaska’s Energy authority to
cultivate crops in biomass heated greenhouses
Source: Frost & Sullivan
The United States Forest Service, an agency of the United States Department of Agriculture, has collaborated with the State of
Alaska’s Energy authority to cultivate crops in biomass heated greenhouses. The produce from these greenhouses will be used
in school lunch programs and utilizing renewable wood energy promotes self sufficiency. The greenhouses also provide
employment to the local people and simultaneously improve both food and energy security. Vegetable production in organic
greenhouses is regularly practised by small-scale farmers.
The South Australian Government has been instrumental in providing the much needed funding for the development of hi-tech
greenhouses developed by Sundrop Farms which will help grow vegetables and fruits. The greenhouses will also use solar
thermal energy to desalinate the water used for greenhouse horticulture. The South Australian Government has provided a
funding of $6 million to Sundrop Farms. This will also provide employment to many rural communities in the northern districts of
the state of South Australia.
Greenhouse Farming
1
2
82Moving forwards, LED grow lights will push controlled environment farming to its
fullest potential, helping urban farmers to increase their yields
Source: Frost & Sullivan
LED vs. CFL & HPS
• LED offers the following advantages
over CFL and HPS:
• Energy efficiency
• Longer lifetime
• 40% less power consumption
However, the cost of LED grow lights is
higher than the other two and the colors
emitted are not easy on human eyes.
Color Spectrum
• Each color emitted from the LED
is responsible for various plant
growth phenomena.
• However, most manufacturers
prefer to use the combination of
red and blue. Red stimulates
photosynthesis and stem
elongation inhibition while blue
stimulates stomatal opening, leaf
expansion and photoperiodic
flowering.
Significance
• LED grow lights are energy
efficient, thereby cutting down on
electricity bills. Also, less heat is
emitted from the light source as
compared to fluorescent lights,
resulting in eliminating or reducing
the cooling loads required.
• Fine-tuning of the wavelength of
light emitted as required by various
crops is made possible by using
LED grow lights.
• Increased yields and extended
growing seasons are the direct
impacts of using LED grow lights.
• LEDs offer more control over the
quality and structure of the crops.
Dynamics of LED
Grow Lights
• Light quality – For optimal plant
growth, the wavelength of artificial
light matters to photosynthetic
pigments. Most plants absorb
wavelengths between 400-700 nm,
depending on the photosynthetic
pigment.
• Light intensity – It is necessary to
study the amount of light required
by any plant grown with artificial
lights and it varies by age and type
of plant.
• Light duration – Light duration
refers to the amount of
uninterrupted dark periods and
light periods. It is the factor directly
impacting the readiness of the
crop, determining whether it can be
harvested or continue its
vegetative growth.
Artificial lighting is the answer for urban farmers who struggle for space and light
for their cultivation. Also, letting optimal light required for plant growth is very
essential. Hence, urban farmers started off using compact fluorescent lightings
(CFL) and High-Pressure Sodium (HPS) lights, but are making the move to light
emitting diode (LED) technology. The LED grow lights replicate the wavelengths
from daylight by emitting precisely the same wavelength required for the vegetative
growth of the crops. LED grow lights offer farmers the control of photosynthesis
during the day and breathing during the night for
accelerated and healthy growth of the plant.
83
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• TBC
Appendix
84IoT in Urban Farming (1/3)The Internet-of-Things provides real-time monitoring of urban farming systems
Source: Frost & Sullivan
Applications
• Plant profile management
• Power management
• Climate management
• Light management
• Nutrient analyzer
• Irrigation management
• Fertilizer management
Components
The components of an IoT enabled
urban farming system include:
• A doser unit to control the nutrient
dosage
• Environmental sensors to monitor
light, temperature and humidity
variables.
• Water sensors to monitor pH and
flow rate of water
• Control unit that manages
communication between all devices
• Dashboard
• Communication devices/ personal
activity trackers
Significance
• IoT mitigates the conventional
challenges of an urban farmer
through quick and automated
control mechanism based on
various farm variables.
• IoT in urban farming, saves time
and money, and reduces the
environmental impact by driving
sustainability.
• IoT gets rid of the ambiguity in
planting and harvesting by offering
growers invaluable visibility and
actionable insights through
predictive analytics.
Advantages
Real-time sensing and monitoring of
temperature, humidity, light intensity
and more, aiding improved production
rates.
Remote operations support enabling
the farmers to make informed
decisions regarding the planting,
fertilizing, and harvesting of crops.
Predictive and dynamic data
analytics to arrive at optimum
conditions for plant growth and
predicting growth and climate patterns.
Integration of components mitigating
the need for multiple monitoring
devices.
Preventive than reactive control
measures through real-time feedback
Autonomous operation of farming
achieved through actuators and robots
with zero to less human intervention.
Internet-of-Things (IoT) is a network of physical objects with embedded
electronics, sensors, actuators, connectivity, and software. It enables the sensing
and controlling of any object remotely through network connectivity. IoT in urban
farming involves the use of various IoT components to sense and measure farm
variables, enabling increased production yields. The aim of IoT is not only data
collection but to analyze the data to evaluate the needed control mechanism. The
application of IoT in urban farming results in smarter
produce by informed farmers.
The use of wearable personal activity trackers is on the rise among the urban
population. However, the integration of the same with urban farming is still in
development with commercialization expected in 2018
85IoT in Urban Farming (2/3)IoT in indoor gardens has the potential to enable connectivity with activity trackers
Source: Frost & Sullivan
1 2 3 4 5 6 7 8 9
IoT enables urban farming initiatives that are simpler and easier to adopt and set up
inside their homes to grow clean and healthy food. With digital infrastructure in place,
cities utilize the power of IoT in indoor gardening to monitor and maintain gardens. Urban
farmers are subjected to a busy lifestyle and IoT simplifies the process of integrating
farming into their day-to-day life. This is achieved by caretaking the indoor gardens by
providing a control/monitor platform to the users through their smartphones or webpages.
With the advent of personal activity trackers, urban farmers are on the lookout for an
integration of urban farming and activity trackers to collect data from trackers and control
the farm produce accordingly to cater to the diet needs of the urban farmer.
Need for the innovation
• Sprouts.IO (US) caters to the indoor smart garden needs through its
microgarden known as ‘device’ and its mobile app known as ‘SproutsIOGrow’.
The integration of the microgarden with the mobile delivers a personalized
produce based on the nutrition facts delivered to the garden through personal
activity trackers.
• Foop (Japan) is a hydroponic based indoor garden, offering rich experience
through its sleek design of gardens and feature rich mobile app. The features are
customized and available in three variants – standard, lite, and premium.
Stakeholders
Significance
• Real-time garden growth data and predictive growth cycle and harvest scheduling that
can connect to personal activity trackers, meal planners and calendars so the produce
can be customized and be made more healthier according to the diet needs of the
urban farmer.
• The farmers receive real time notifications in their smartphones and personal activity
trackers while at home, work or play.
• IoT enables seamless integration of the devices such as smartphones, smart indoor
gardens and personal activity trackers and serves as a communication platform for
data exchange.
• Ease of monitoring and control through applications developed for multiple platforms
such as mobile phones, webpages, smart wearables and more.
Market Readiness Level
Impact
Integration of personal activity trackers with urban farming using IoT helps in
achieving increased produce along with personalized clean and safe food according
to the diet needs of the urban farmer.
Technology providers will adopt open API based IoT enabled
hydroponics and aquaponics system when there is increased consumer
awareness in the urban farming sector on the technology front.
86IoT in Urban Farming (3/3)Open API-based IoT in hydroponics results in cost reduction and customization
Source: Frost & Sullivan
1 2 3 4 5 6 7 8 9
Since 2014, there has been an influx of IoT enabled hydroponic and
aquaponic gardening systems offering superior automation and control over
various parameters. However, the adoption rate has been slow due to the
high capital costs involved in the automation of the farms. The key
contributor to the cost is the Application Programming Interface (API)
developed for the monitoring and control operations using IoT. Additionally,
the APIs are predominantly closed natured, restricting any customization of
the control and monitoring systems.
Need for the innovation
Open Aquarium and Open Garden by Cooking Hacks is built on an
open API platform to automate control and monitoring of various
gardening parameters with the use of sensors and IoT-enabled devices.
It is mainly aimed at improving the scalability of the solutions based on
IoT for urban farming.
Stakeholders
Significance
• Cost reduction – Automation is the crux of hydroponic and aquaponic
systems and the high initial cost associated with the integration of
devices using IoT can be drastically reduced with the use of open APIs.
• Scalability – open APIs render ease of scalability in the automation of
devices when the urban farmer is scaling the farm. The required changes
can be integrated with minimal effort through a web application hosted by
an open sourced platform.
• Ease of adding/removing control devices – If open sourced API is
adopted, the farmer can add/remove a measuring device and it can be
easily interfaced with the software for improved control measures.
Market Readiness Level
Impact
The cost of automated hydroponic and aquaponic systems is expected
to drastically reduce by adopting open APIs. This also offers a rich user
experience, allowing the urban cultivator to customize the software
according to his/her needs.
87Circular Economy (1/3)The ideal waste management hierarchy dictates that food should only be diposed of as a last resort
Reduction in food waste
• Food waste production can be reduced by using better infrastructure and reducing unwise consumption patterns
Diversion of excess food
waste
• Concepts such as food banks are handy in the management of excess food. Food unfit for human consumption may be used as feed for livestock
Conversion of food waste into
outputs
Disposal of food waste
• Disposal is the final option for food waste management and should be given the least priority
• This involves the extraction of valuable outputs such as energy and chemicals from the remaining food waste.
Source: Frost & Sullivan
88Circular Economy (2/3)Companies such as Marks & Spencer are working with app developers to divert excess to food banks
A food bank itself is an efficient concept to curtail food waste. It is
finding greater adoption in the developed world and slowly attracting
attention in the developing world too with the benefits it presents.
The success of the model is highly dependent on coordinated
functioning among its stakeholders. Food banks globally follow
different models of operation.
Food bank usage is found to be especially high in countries such as
Germany and France. The United Kingdom (UK) also saw a drastic
rise in the number of food banks from the 2000s. Food banks have
been recognized as agents of social change by addressing the dual
issues of hunger and poverty. Food banks are major support
systems for the lower income working class in many developed
countries.
Marks & Spencer (UK) has a commitment for reducing food waste by
a fifth by 2020. The company plans to distribute surplus food with the
aid of a social networking app, which will act as a link between its
stores and local charities, inclusive of food banks in the UK. The
company has been testing various ways of operating the scheme.
The scheme will be executed using the app called Neighbourly,
developed by Neighbourly (New Zealand).
Stakeholders
Individuals
NGOs
Charities
ConsumersGovernment
Industries
Food Bank ModelDiversion
Source: Frost & Sullivan
89Circular Economy (3/3)Dublin Institutie of Technology is leading research to convert waste into ingredients like beta glucan
The School of Food Science and Environmental Health, Dublin
Institute of Technology, Ireland is conducting research to extract
food ingredients from food waste such as beta glucan from spent
grain of breweries; chitin from mushroom waste; glycoalkaloids from
potato peel; and probiotics and probiotic beverages from various
types of food wastes.
Recovery of biomolecules is also being considered by many
organizations.
Pineapple processing waste is being considered as a source of
enzyme bromelain. Research on this has been conducted at a
number of universities such as Mae Fah Luang University, Thailand
and East Point College of Engineering and Technology, India,
among others.
Outputs
Enzymes
Organic acids
Food additives
Pharma products
Functional foods
Selected outputsConversion
Source: Frost & Sullivan
90Principal abbreviations
APAC Asia Pacific M Million
B Billion NA North America
CAGR Compound Average Growth Rate NASA National Aeronautics and Space Administration
CFL Compact Fluorescent Lighting NSF National Science Foundation
EFSA European Food Safety Authority OPEX Operating Expense
EU European Union PHMB Polyhexamethylene Biguanide
FDA Food and Drug Administration R&D Research & Development
FSMA Food Safety Modernization Act ROW Rest Of The World
HAI Healthcare-Associated Infection TSE Twin Screw Extrusion
HPS High-Pressure Sodium UK United Kingdom
IOT Internet Of Things US United States
LED Light Emitting Diode USD United States Dollar
91
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• TBC
For further details on Frost & Sullivan’s coverage and services,
please contact Livio Vaninetti, Director of Frost & Sullivan Italy
June 2018
for further information about this report please contact