focus will curing blindness bring peace?
TRANSCRIPT
S o u t h S u d a n P e a c e c i r c l e
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40 years of civil war... Will curing blindness bring peace?
university of utah health care
John A. Moran Eye Center
Moran advisory council2
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Wayne ImbrescIa John A. Moran Eye Center
claudIa s luttrell Salt Lake City, Utah
robert e marc, Phd John A. Moran Eye Center
John a moran Palm Beach, Florida
randall J olson, md John A. Moran Eye Center
chase n Peterson, md Park City, Utah
lynn Ward John A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye Center
steve Wynn Las Vegas, NevadaLas Vegas, NevadaLas Vegas, NevadaLas Vegas, NevadaLas Vegas, Nevada
norm a ZabrIskIe, md John A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye Center
robert F bennett Falls Church, Virginia
John bloomberg La Jolla, California
reed brInton Salt Lake City, Utah
alan s crandall, md John A. Moran Eye Center
Ian cummIng Jackson Hole, Wyoming
steve deZII Las Vegas, Nevada
sPencer F eccles Salt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, Utah
gregory s hageman, Phd John A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye Center
alan hIrschFIeld Jackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, Wyoming
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2 Message from the Chair The Words of a Mother, the Miracles of Vision and Peace Today
4 South Sudan Seeing Your Enemy in a New Light
8 Night for Sight Dedicated Volunteers, Friends, and Generous Donors
10 Highlights
13 Ophthalmologists
18 Val A. and Edith D. Green Foundation Three Generations of Giving
19 Every Little Bit of Kindness Comes Back
22 Charitable Saturday Surgery Day
24 Andy’s Unexpected Pit Stop
27 Research Team
30 Our Mission is Remission Diagnosis and Treatment of Uveitis
32 Moran Researchers Upend Prevailing Theories about Rare Childhood Disease
34 Shedding New Light on Retinopathy of Prematurity
36 Residents and Fellows 2013-2014
38 Moran’s New Resident Continuity Clinic
40 A Clear Vision of Service
41 Community Clinics
42 David Kelby Johnson Hope Fund
44 The Expanding, Enduring Legacy of Sam Skaggs
46 Second Suns Moran’s Drs. Geoffrey Tabin
and Sanduk Ruit
48 Donors 2012
54 Appointments, Honors, and Awards 2012-2013
56 Industry Leadership and Service
62 Clinical Trials
64 Technology Commercialization and Intellectual Property/Patents 2012-2013
66 Grand Rounds
68 Published Research
72 Research Grants and Contracts 2012-2013
79 National and International Presentations
Official Publication of the John A. Moran Eye Center University of Utah Health Care, Salt Lake City, Utah 84132
John A. Moran Eye Center 65 Mario Capecchi Drive Salt Lake City, UT 84132 801-581-2352
EDIToR Steve Brown, Communications Manager
ExTERNAL RELATIoNS TEAM/CoNTRIBUToRS Linda Bult, Editor, WriterTawnja Carballo, Development SpecialistB.J. Fullmer, Administrative AssistantKirsten Mallik, Director of DevelopmentEsther Pomeroy, Communications SpecialistHeidi Reid, Development OfficerLynn Ward, Executive Director
INTERNATIoNAL DIVISIoN oF oPHTHALMoLoGy AND LoCAL oUTREACH Julie Crandall, Project Coordinator Tara Kisow, Program Coordinator Michael Yei, Manager
CoNSULTANTS Virginia Rainey, Editor, Writer
GRAPHIC DESIGN Spatafore & Associates
PHoToGRAPHy Steve BrownLaurel DokosJames Gilman, CRA, FOPSBryan W. Jones, PhDAce KvaleSteve LeitchBrandee MichaelsonTimmy O’NeillPatrick ReddishMichael Schoenfeld
PRINTING Printers Inc. Salt Lake City, Utah
A special thanks to the many hard working Moran Eye Center employees, management, health care workers, physicians, patients, and researchers who generously contributed their time and talent to make this publication possible. Special thanks also to Kay Spatafore and Lori Garfield, Designers.
For more information about the Moran Eye Center, visit our website: www.moraneyecenter.org. Follow us on Facebook at Moran Eye Center and on Twitter @MoranEyeCenter. Requests for additional copies of this publication may be sent to the following: Communications Manager, Moran Eye Center, 65 Mario Capecchi Drive, Salt Lake City, Utah 84132.
©2013 John A. Moran Eye Center. All rights reserved. The Moran Eye Center does not assume responsibility for any representation therein, nor the quality or deliverability of the product themselves. Reproductions of articles or photographs, in whole or in part, contained herein are prohibited without express written consent of the publisher, unless otherwise stated.
J o H N A . M o R A N E y E C E N T E R
ContentsFOCUS 2013
patient care1
research
outreach
education
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“When Dr. Olson told me about his dream to carry out research that might someday restore vision to the
blind, it brought to my mind stories my mother read to me as a child,” John says. “As a little boy, I was
particularly touched by the stories of the blind beggar, the power of faith, the miraculous restoration of
sight, and being kind to our neighbors as well as toward strangers. One of the reasons this building exists is
because my mother planted within me a belief in miracles. Even today, these many decades later, my vision
of life’s possibilities is influenced by my mother’s love.”
I’ve told John’s story many times, but it feels especially fitting for this publication as we spotlight our outreach
programs. I watch in awe as this simple yet profound story plays out through our local and international
charitable programs every day. While I’m confident the devoted researchers at the Moran Eye Center will
play a big role in discovering treatments and cures for blinding eye diseases in the near future, until that time
comes, we will bring sight to as many individuals with curable blindness as we can—not sometime in the
future, but today. Fulfilling the vision that John Moran’s mother instilled in him as a young boy cannot wait!
We receive word of these modern miracles of sight restoration through regular updates from our doctors in
the field. Here’s an example from our most recent mission to South Sudan.
Message from the Chair
Did you know that by the age of eight, the average child has heard between 13 and 48 million words from his or her mother? Our mother’s words act as a compass as we navigate through life. When we’re young, we may reject them, but soon we lean on them, recite them, and eventually live by them. John Moran, our chief benefactor and namesake, can point to words his mother said that changed not only his life but the lives of countless individuals throughout the world.
mir
ac
lesThe Words of a mother, the miracles
of Vision and Peace Today of Vision and Peace Today
Randall J Olson, MD, Professor and Chair Division of Ophthalmology, University of Utah; CEO Moran Eye Center
Young South Sudan patient will soon see again
sighT
Journal entries from the lost Boys clinic, south sudan:
Our first story in this issue is about the Moran Eye Center’s five-year commitment to help cure treatable blindness in
the world’s newest, and one of the most violent countries, South Sudan. It is also about peace. It’s about a second
miracle where the leaders of three warring tribes came together in a peace observance with their fellow South
Sudanese citizens—regardless of tribal affiliation—who had received the gift of sight. We have now watched this
extraordinary event take place and, in this issue, you can read about its extraordinary effects on the lives of individuals
and the improved situation between the various tribes.
This year, we celebrate the twentieth anniversary of the John A. Moran Eye Center. In the appendix of this annual
report, we highlight our growth and accomplishments for 2012; but perhaps one of our most extraordinary
achievements can be found in the evidence from South Sudan—that we are successfully navigating the compass
points taught to John Moran by his mother.
Peace
Randall J Olson, MD Professor and Chair of OphthalmologyCEO, John A. Moran Eye CenterUniversity of Utah
Day Three “The team completed 34 cataract surgeries. Patients from all three opposing tribes (the Nuer, Dinka, and Murle) were brought together under the dire circumstances of blindness.”
Day Four “The team completed 34 more cataract surgeries. While some spent endless hours in the extremely hot operating room, others offered post-operative care for patients in the blazing sun.”
Day Six “The peace initiative was a huge success. Formerly blind patients, their families, and leaders from the warring tribes gathered together in peace to discuss how the sight-restoring surgeries will change their lives. The evening concluded with a group hug between the three tribes, resulting in tears from all.”
—Michael Yei, Moran International Division Manager
South Sudan Peace Circle 2012
Lloyd Williams, MD, John Dau, Alan Crandall, MD, Geoffrey Tabin, MD—South Sudan 2011
John Dau and Randall J Olson, MD
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Seeing Your Enemy in a
New Light
Seeing Your Enemy in a
What can one man and ophthalmologists from the Moran Eye Center do to bring peace to South Sudan that United Nations peacekeepers, diplomacy, and millions of dollars in international aid have struggled to do? The answer lies in a simple ten-minute sight-restoring surgical operation and a commitment to peace.
Hope and Heartbreak South Sudan is the newest country in the world and one of the poorest. �ere are literally no ophthalmologists in this country of ten million, resulting in nearly one million of its citizens living with blinding eye diseases. Tragically, the vast majority of these individuals could have their sight restored with a common eye surgery. Everyday life is a struggle to survive in South Sudan, but becoming blind is an early death sentence—without the ability to see, a blind person cannot care for him or herself and is a physical and �nancial burden to family, village, and nation.
In 2011, South Sudan gained independence, but at a devastating price: between 1983 and 2005, 2.5 million Sudanese were killed in the civil war, leaving behind more than 20,000 displaced or orphaned children. �ousands of those children, known as the “Lost Boys of Sudan,” �ed the war on foot over 1,000 miles to Ethiopia. John Dau is one of three leaders of 3,800 Lost Boys who relocated to the United States. His horri�c experiences compelled him to establish the John Dau Foundation and open the Duk Lost Boys Clinic in his home village of Duk Payuel.
Dr. Alan Crandall and John Dau—Sowing Early Seeds of Peace In 2006, Moran’s Dr. Alan Crandall, Co-director of the Division of International Ophthal-mology and Professor and Senior Vice Chair of Ophthalmology at the University of Utah, met John Dau. Dr. Crandall had been performing sight-restoring missions in other parts of Africa for more than a decade. Moved by the younger man’s remarkable vision and tenacity, Dr. Crandall pledged to bring eye care to the Duk Lost Boys Clinic.
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South Sudanese man needlessly blind from untreated cataract
A blind patient in South Sudan has his eyes examined before surgery
Dr. Tabin, John Dau and Dr. Crandall, 2011 South Sudan mission
In December 2011, a Moran surgical team was �nally able to enter the country, but only under the protection of armed guards. "�is was actually our third attempt to go into this region. Twice we were turned back because of violence, but we persisted,” says Dr. Crandall.
�e �rst eye camp was a challenge unlike anything the Moran team had ever experienced. In high humidity with tempera-tures exceeding 105 degrees, the cinder block operating room allowed insects, bats, snakes, and lizards to �y and slither through open entryways and windows. �e electricity would cut o� without warning. Patients walked for days through a war zone to get to the clinic. �ere was disease and malnutri-tion at every turn. Despite these extreme conditions, the eye camp was a success. Two hundred forty-one people received the gi� of sight through cataract and trachoma operations. Skeptical patients, who arrived at the clinic led with a stick by their children, departed under their own power.
�e Moran team was also reminded of the violence all around them. �ey heard daily gun�re, and during their stay, 40 people in a nearby village were killed and 16 children were taken into slavery. A�er the team le�, a wave of intertribal vio-lence surfaced in a village just 150 miles southeast of the clinic that took the lives of 3,000 individuals. Tragically, one of the patients, Lonnie, who had his sight restored at the clinic, was killed shortly a�er leaving.
A Commitment to Peace During the 2011 mission, Dr. Crandall made a commitment to Dau that he would carry out four more medical missions to South Sudan. In addition, Dau suggested that as a way to miti-
gate South Sudan’s continuing warfare, the Moran team could tie future medical missions to peace; Dr. Crandall agreed. �e Moran team would not return to perform eye surgeries unless the warring tribes pledged to assemble together in peace for a shared eye camp. With this mandate, a�er the clinic ended, those who had been given the gi� of sight and their families and friends returned home and spread the wonderful news of the eye camp and the conditions for the next one. Local and state agencies also spread the word about the clinic and the peace agreement throughout the region, and many of the tribal leaders agreed to the terms.
Sight is a Precious Thing Jump ahead one year to December 11, 2012. A ��een-member medical team from Moran arrived for a second eye care mis-sion at the Lost Boy’s Clinic with hope that their plan for a peace summit would become a reality. �e team included ophthalmologists Roger Furlong, Alan Crandall, and Charles Weber. �e team packed 2,000 pounds of their own equipment over 8,000 miles to be “greeted by a lot of smiling faces,” said Dr. Weber.
Wary of other warring tribes, once again hundreds of blind, hungry, and sick Sudanese walked miles to the Lost Boy’s Clinic, risking their safety for the promise of sight. Over 600 were screened. At the end of the week, 227 individuals, includ-ing Murle, Nuer, and Dinka tribal leaders, gained sight—some for the �rst time—others a�er years and even decades without vision.
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�e experience was profound. As the surgical bandages were removed during the week, warring tribal members saw each other—for the �rst time—as comrades, relishing the gi� of sight—not as mortal enemies. “�is is a very stoic culture,” said Dr. Weber. “�ey usually don’t show any kind of out-ward emotion. But to see patients break out in song and hug is pretty incredible.” Moran International Division Manager Michael Yei reported at the time: “I just watched two elderly women, post-op, wander through the camp looking up at everything and occasionally stopping to hug each other. Sight is a precious thing.”
Drunk from Love Near the end of the eye camp, the stage was set for a special planned peace circle. Imagine if you will, the following scene as depicted by several who experienced this event: Patients from the warring tribes and their leaders, friends, and families are sitting in a circle under the quiet beauty of the African
South Sudan tribal leaders and John Dau (right foreground) discuss improving relations during peace circle ceremony, 2012, as Moran’s medical team looks on.
Pre-op patients
skies—many patients are seeing the sunset or the faces of their children or grandchildren for the �rst time. As they look across the circle, they see the faces of patients from other tribes in a whole new light.
�e sudden gi� of sight produces such overwhelming joy in the circle that thoughts of war, hatred, and anger dissolve. Former enemies become kindred souls. �ey smile at each other and tears �ow as they embrace—now citizens of one nation. Dau described the experience this way, “Patients looked absolutely like they were drunk, and actually they were drunk—from love. You can see clearly that there is love among the people of Jonglei State!”
When all have assembled, Dau stands up to speak. He is all of six-feet, eight-inches tall with a captivating voice and an eloquent manner. A report from the �eld says that all eyes are on him, as he says to the group, “We want to disarm your hearts,” earning him a sincere round of applause.
�e Moran team needed key words such as “Don’t move” translated into three tribal languages
“As the surgical bandages were removed during the week, warring tribal members saw each other—for the �rst time—as comrades, relishing the gift of sight—not as mortal enemies.”
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Post-op patients participating in the peace circle
Dau continues to inspire, and his message is truly felt by members of all tribes. He then opens up the discussion. In a statement that re�ects the feelings of all the patients, a woman declares, “Peace is possible when you can see the other party. Now that we can see each other, let us unite and become mes-sengers for peace.”
Peace is Possible When You Can See the Other Party �ere have been con�icts in other parts of South Sudan since the 2012 camp. Yet, a�er the latest eye mission and the peace circle, a recent report said there has been peace in the region for the �rst time in many years. A John Dau Foundation trip report on the 2012 eye camp included remarks from patients who participated in the peace circle:
Police First Lieutenant Lam Kong from Uror County who was partially blind by cataract said, “�e �rst time I have heard of someone who have restored eye sights for free is in the Bible…
and the second time is today, and they are these doctors. Lou Nuer and Jiang (tribes) are now one people, and you will never hear of any con�ict again.”
Elijah Bol Kuot from Twic East County said, “For those whose eye sight was restored, will you not communicate this miracle that has happened to your youth to stop raiding other villages? Peace is possible when you can see the other party. Now that we can see each other, let us unite and become the messengers for peace in Jonglei State. Let’s stop our thieves from causing trouble to the neighbor country.”
Nyaboth Tutdel from Ayod County said, “Americans who were brought here by John Dau are either sent by God or they are the real God’s people. How can they leave their families behind and come to help open our eyes?”
Patients wait to have their eyes screened
“Patients looked absolutely like they were drunk—actually they were drunk, from love. You can see clearly that there is love among the people of Jonglei State!” —John Dau
2014
“DISARM THEIR HEARTS” A Vision of SustainabilityThe Sudanese people have experienced only 15 years of relative peace in the past 60 years. Like all peace initiatives, this one will take time to measure in terms of long-term success. After hearing the success of the first sight-restoring peace initiative, leaders from other states now want Moran ophthalmologists to bring eye care missions and the peace ceremony and experience to their residents.
A team from the Moran Eye Center is preparing to carry out a third mission to South Sudan in January 2014. The goal is to bring sight to more than 300 members of multiple tribes from the extremely isolated and neglected region that has been called the “Conflict Triangle.”
While these first missions are important, with almost one million citizens of South Sudan experiencing blindness year after year, at this rate it would take more than 3,000 years just to restore their sight. Fortunately, it won’t take that long. A key component of our international outreach vision and the vision of the John Dau Foundation is one of self-sustainability. With continued support from many wonderful people, one day these clinics will be staffed and run by the people of South Sudan—and the good news is, this program has already begun.
Two assistants from the Lost Boy’s Clinic recently went to Nairobi, Kenya for ophthalmic training and will return to Sudan as certified technicians. It won’t be long before they will be able to treat trachoma by themselves and to train other South Sudanese to do so, long after the Moran team is gone. It is our vision that in the not too distant future, eye care will become self-sustainable in South Sudan, and vision clinics that include peace ceremonies will become a yearly tradition that spreads across all 14 states in that country, so that everyone will have a chance to “disarm their hearts.”
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Night for Sight
2013
Thanks to a stellar committee and more than 530 supportive guests,
sponsors, and donors, The John A. Moran Eye Center’s annual Night for Sight gala was
a rousing success. Held on June 22, 2013, at Salt Lake’s Grand America Hotel, Moran’s
premiere fundraiser brought in much-needed funds to support local and international
outreach programs that are an integral part of our mission to treat and cure preventable
blindness and vision loss at home and around the world.
Amid panels of stunning, large-format photography
that documented Moran’s charity care locally and
abroad, guests gathered for an elegant reception and dinner along with live and
silent auctions. Bidding opportunities were as varied as a chance to drive BMW race
cars on a private track to working alongside Moran medical teams at surgical eye
camps deep in the Himalayas. Guests bid on many one-of-a-kind items, including
“The World’s Best Dinner Party” with chef Mikel Trapp and a private concert with
Emmy-winning composer Kurt Bestor. Another opportunity celebrated “The Kid
Inside” with a chance for 20 friends to join in a day of grown-up “sandbox” play,
learning and operating a full suite of earth movers from Intermountain Bobcat, and
savoring a privately catered south-of-the-border style dinner afterwards.
Dedicated volunteers, friends, and generous donors create a special evening to remember
Moran doctors in South Sudan
Short films illustrating Moran’s outreach efforts rounded out the evening, as did an inspiring speech by Moran CEO and Department Chair Dr. Randall Olson. Attendees learned about the unprecedented five-year peace and sight-restoration mission that Moran is carrying out in South Sudan in an alliance with John Dau and the Duk Lost Boys Clinic. Moran surgeon Dr. Geoffrey Tabin, the subject of the highly anticipated best seller Second Suns, also read touching passages from the book.
Everyone who attends or volunteers at Night for Sight is a critical part of our effort to end unnecessary blindness. Donors of time or money support a proud tradition that spans three decades of providing medical care for the underserved, locally and around the world. Just last year, Moran Eye Center ophthalmologists donated their time and talents carrying out sight-restoring missions in fourteen countries on five continents. Moran doctors are also training doctors from Ethiopia, Tanzania, Ghana, Nepal, China, Trinidad and Tobago, India, Bhutan, El Salvador, South Sudan, Indonesia, and Kenya to perform sight-restoring surgeries in their own countries.
Special thanks to our Honorary Chairs John and Marva Warnock, Event Chair Carol Firmage, and the volunteer committee who worked tirelessly to create such a special evening. Thanks also to Drs. Geoff Tabin and Alan Crandall, co-directors of Moran’s International Division. We are also grateful to the many community and business leaders throughout the Salt Lake Valley, Park City, and the entire Wasatch Front who participated in the event. And finally, a sincere thanks to the medical professionals from Moran and all of our industry partners who volunteer time and resources to do outreach work in Utah and around the world.
See the video shorts and learn more about Night for Sight at www.moraneyecenter.org. If you are interested in volunteering, attending, or receiving information about sponsoring the next Night for Sight, please contact the Moran Eye Center Development Office at 801-585-9700 or email [email protected].
THANK YOU TO OUR NIGHT FOR SIGHT SPONSORS
Presenting SponsorsBMW of Murray
BMW of Pleasant Grove
MINI of Murray
Elizabeth A. Johnson, in memory of David Kelby Johnson
O.C. Tanner
John and Marva Warnock
Platinum SponsorsBamberger-Allen Health & Education Foundation
Grand America Hotel
Claudia Skaggs Luttrell
Reagan Outdoor Advertising
Visionary SponsorsJohn and Toni Bloomberg
George S. and Dolores Doré Eccles Foundation
FFKR Architects
SD Stewart Foundation
Zions Bank
Table SponsorsBennion Jewelers
EnergySolutions
Fred and Christine Fairclough
FreeportWest Industrial Properties
Justin Grant Photography
Legislative Insight Consulting LLC
Lipman Winston
Mayor Ben McAdams
Molina Healthcare
Julie Nester Gallery
HONORARY CHAIRS John Warnock, Scott Murray, Marva Warnock; Event Chair Carol Firmage
Mark Miller, Dr. Randall J Olson Dr. Geoff Tabin
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m o r a n e y e c e n t e r H I G H L I G H T S
RANDALL J OLSON, MD, Professor and Chair of Ophthalmology and Visual Sciences, CEO, John A. Moran Eye Center, University of Utah School of Medicine
Dr. Randall J Olson completed his undergraduate training and medical schooling at the University of Utah (BA ’70, MD ’73); his residency at UCLA in 1977 in ophthalmology; and fellowships in cornea at the University of Florida in Gainesville and at the Louisiana State University Eye Center in New Orleans, where he joined the faculty in 1977 as Director of Corneal Services. Dr. Olson started as a one-person Division Chief in June, 1979, at the University of Utah and has been Chief of Ophthalmology ever since. During this time, he has directed the building of two eye centers and managed faculty that has expanded from one to over fifty members today. And now, more than half of the current 210,000-square-foot Moran Eye Center, built in 2006, is dedicated to research.
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DDr. Olson Receives Four New HonorsThe Moran Eye Center faculty, staff, as well as our patients, supporters, and friends feel it is a privilege to work with our remarkable chair and CEO, professor and surgeon, Dr. Randall J Olson. It is always special when we hear that Dr. Olson has received an honor from his colleagues, universities, or other institutions. Adding to his many awards, we’re pleased to announce that Dr. Olson recently received FOUR major accolades:
The Fourth Annual Distinguished Ophthalmic Educator Award, University of Iowa Carver College of Medicine, Iowa City, Iowa, May 17, 2013. Dr. Olson was also guest faculty and the keynote speaker at this event. This award was given to Dr. Olson for his many accomplishments and years of contributions to ophthalmology, education, and patient care.
The Dr. Clark Lowe Rich Distinguished Surgeon Award. Educator, University of Utah, Salt Lake City, Utah, May 23, 2013. This award recognizes one outstanding surgeon each year at the University of Utah who has demonstrated exceptional skill and dedication in the field of surgery, including teaching, advising, and mentoring medical students, interns, residents, or fellows. The recipient is a role model in the tradition established by Dr. Rich during his lifetime of service in surgery and patient care.
The 34th Annual Tullos O. Coston Lectureship at the Dean McGee Eye Institute, University of Oklahoma, Oklahoma City, Oklahoma, June 8, 2013.This lectureship was established in honor of the enormous contributions of founding ophthalmic surgeon Dr. Tullos O. Coston. Held at the Annual Resident and Alumni Meeting, distinguished ophthalmologists are invited to share their research, interest, and expertise.
The 44th Annual Jules Stein Pettit Lectureship Award, Jules Stein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, California, June 14, 2013. The Pettit Lecture is awarded to clinical researchers with outstanding research throughout their careers, who are invited back to the institute where they trained, to share their findings with the residents, fellows, and faculty of the Jules Stein Eye Institute and the UCLA School of Medicine.
Four Major Awards
Balamurali K Ambati, MD, PhD, MBA is Appointed the Official Utah Utes Team OphthalmologistDr. Bala Ambati, Professor, Department of Ophthalmology and Visual Sciences and Adjunct Associate Professor of Neurobiology and Anatomy at the University of Utah Health Center was appointed team ophthalmologist for the University of Utah Utes in August 2012. “I’ve always been interested in eye trauma, sports medicine, and the Utes,” says Dr. Ambati. “I take care of coaches and staff as well as the athletes. I’ll treat any injuries to the front of the eye such as scratches, rup-tured globes, chemical burns—and perform routine eye exams and treat any eye diseases that they may have.”
Dr. Ambati also provides eye injury prevention, eye trauma, and eye health edu-cation for athletes and coaching staff. He cannot stress enough the importance of wearing protective goggles to avoid foreign objects getting into or hitting the eyes. He would like to express his “special thanks” to Trevor Jameson, the Utes’ head athletic trainer.
Dr. Ambati has the distinction of being the world's youngest person to graduate from medical school at age 17. He is experienced in cornea transplants, cata-ract extraction, keratoprosthesis (artificial cornea), LASIK, and other complex procedures of the cornea and anterior segment of the eye. He conducts pioneer-ing work in showing what keeps the cornea clear and is developing novel drug delivery systems for several eye diseases.
Unprecedented—Nick Mamalis, MD, Named Moran’s Second Binkhorst Medal Winner Dr. Nick Mamalis, Professor of Ophthalmology at the University of Utah, has received the American Society of Cataract and Refractive Surgery’s (ASCRS) greatest tribute—the Binkhorst Medal of Honor, an award of global prominence. This award marks an unprecedented honor for Moran Eye Center, as Dr. Randall J Olson was the 2012 recipient. Binkhorst Medal winners are selected for their “significant contributions to the science and practice of ophthalmology.”
Dr. Mamalis’ work, specializing in the study and understanding of toxic anterior segment syndrome, has established him as a leader in the field of ophthalmol-ogy. He was presented with the award at the ASCRS and American Society of Ophthalmic Administrators Symposium and Congress in San Francisco, April, 2013, where Dr. Mamalis delivered the Binkhorst Lecture.
His lecture, “Intraocular Lens Evolution: What a Long, Strange Trip it’s Been,” explores the “history and future of IOL implantation and traces surgical techniques from the beginning to the next technological frontier in providing clear and uncorrected distance, intermediate, and near vision following cataract surgery.”
Dr. Mamalis is a practicing ophthalmic surgeon, Director of the Ophthalmic Pathology Laboratory at the Moran Eye Center, Co-director of the Intermoun-tain Ocular Research Center, Chairman of the ASCRS Task Force, and an editor of the Journal of Cataract & Refractive Surgery.
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Binkhorst Medal
Utah Utes Team Ophthalmologist
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Yingbin Fu, PhD, Wins “Challenge to Identify Audacious Goals” Dr. Yingbin Fu, Assistant Professor of Neurobiology & Anatomy, Neuro-sciences, Molecular Biology, and Director of Model Development, Moran Center for Translational Medicine, was one of 10 esteemed winners of the National Eye Institute (NEI) “Challenge to Identify Audacious Goals in Vision Research and Blindness Rehabilitation,” 2013. His winning submission: “Precise Gene Editing In Vivo” aims to permanently correct (by being delivered safely and efficiently into the eye) any disease-associated mutations in a patient through the use of molecules specially designed to target mutated DNA sequences.
“If this goal is achieved, the impact would be enormous in the prevention and cure of human diseases,” Dr. Fu said. “As we enter the era of person-alized medicine, it has become more and more practical to sequence a person’s genome at low cost, which makes it possible for us to catch disease-causing mutations early and before the onset of disease.” Beyond eye disease, this strategy could also be applied to the genetic component of virtually any human disease, whether inherited or resulting from cellular responses to environmental stresses.
“It is an incredible honor for the Moran Eye Center and for Dr. Fu to receive this prestigious and well-deserved award,” said Dr. Randall J Olson, Chair-man and CEO, John A. Moran Eye Center. This work is truly ‘audacious’ in the best sense of the word and revolutionizes this area of science.” In 2012, Dr. Fu was also presented with the “National Eye Institute Travel Award” at the XVth International Retinal Degeneration Symposium, Bad Gögging, Bavaria, Germany.
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Dr. Yingbin Fu with Director of the National Eye Institute, Paul Sieving
Challenge to Identify Audacious
Goals in Vision Research and
Blindness Rehabilitation
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CEo of the John A. Moran Eye CenterRandall J olson, MD, is the chair of the Department of ophthalmology and Visual Sciences and ceoof the John A. Moran Eye Center. Dr. Olson is the author of more than 300 professional publications and a worldwide lecturer. He specializes in research dealing with intraocular lens complications, tele-ophthalmology, and corneal transplantation techniques. He was selected as one of the 15 best cataract surgeons in the United States in a peer survey conducted by Ophthalmology Times. Cataract and Refractive Surgery Today named Dr. Olson as one of 50 international opinion leaders. Time constraints limit the Surgery Today named Dr. Olson as one of 50 international opinion leaders. Time constraints limit the Surgery Todaynumber of patients Dr. Olson is able to see, yet he continues to enjoy patient care visits on a regular basis.
specialty• Cataract Services and External Eye Diseases
Doctors in Alphabetical Order
Balamurali K Ambati, MD, PhD, MBA, specializes in cornea transplants,cataract extraction, keratopros-thesis (artificial cornea), LASIK, and other complex procedures of the cornea and anterior segment of the eye. He welcomes patients in these areas as well as general ophthalmic issues. Dr. Ambati also maintains a dynamic research laboratory and has more than forty peer-reviewed publications and two books.
specialties• Cornea• Cataract Services• Vision Correction Surgery
(LASIK, Laser, and Non-laser)• Uveitis
Paul S Bernstein, MD, PhD,specializes in age-related macular degeneration with special em-phasis on the role of nutrition and environment in its treatment and prevention; inherited retinal and macular dystrophies; and surgical treatment of vitreoretinal disor-ders such as diabetic retinopathy and retinal detachments.
specialties• Vitreoretinal Diseases
and Surgery • Retinal Biochemistry• Macular and Retinal
Degeneration
Alan S Crandall, MD, is the Senior Vice chair of the Department of ophthalmology and Visual Sciences, Director of moran’s Glaucoma and cataract Division, and Co-director of Moran’s International Divsion. He focuses on the medical and surgical management of glaucoma and cataracts. Dr. crandall has experience with trabeculoplasty and laser cyclo-photocoagulation. He is involved in numerous clinical research studies at the Moran Eye Center, lectures throughout the world, and was selected by Cataract and Refractive Surgery Today and Refractive Surgery Today and Refractive Surgery Todayas one of 50 international opin-ion leaders.
specialties• Cataract Services• Glaucoma
Susan Chortkoff, MD, focuses on the management and treatment of glaucoma as well as comprehensive ophthalmology. Dr. Chortkoff also has a special interest in the management of dry eye syndrome.
specialties• Comprehensive Ophthalmology• Glaucoma
William Barlow, MD, specializes in comprehensive oph-thalmology with a focus on the surgical management of routine and complex cataracts, anterior segment surgery, and vision cor-rection surgery using laser and intraocular lenses. His current research interest is focused on cataract surgical outcomes.
specialties• Comprehensive Ophthalmology• Cataract Services• Refractive Surgery (LASIK,
Laser, and Non-laser)
Craig J Chaya, MD, specializes in comprehensive ophthalmology with a focus on the medical and surgical manage-ment of cataracts and glaucoma. Dr. chaya also has an interest in international ophthalmology and has worked in Guam, Pohnpei, Ghana, Haiti, Thailand, and Nepal.His research interests include cataract and glaucoma surgery in the developing world.
specialties• Comprehensive Ophthalmology• Cataract Surgery• Glaucoma
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David C Dries, MD, provides medical and surgicalcare for a wide range of eye diseases and visual impairments in children as well as evaluation and management of strabismus in both children and adults. He has special interest in amblyopia, esotropia, exotropia, retinopathy of prematurity, retinoblastoma, infant and childhood cataracts, and nasolacrimal duct obstruction.
specialties• Pediatric Ophthalmology• Adult Strabismus
R Michael Duffin, MD, practices comprehensive ophthalmology, specializing in cornea and external eye diseases. He joined the Moran Eye Center after 22 years of private practice experience in California. Dr. Duffin has conducted over 25 humani-tarian eye projects, mostly in Latin America, including cataract surgery and cornea transplants.
specialty• Comprehensive Ophthalmology
Jason Goldsmith, MD, focuses on the medical and surgi-cal management of cataracts andglaucoma. Dr. Goldsmith’s researchinterests include the use of opticalcoherence tomography, an oph-thalmic imaging technology used in screening for angle-closure glaucoma.
specialties• Cataract Services• Glaucoma
Joseph L Hatch, MD, provides expertise and experi-ence in all areas of ophthalmology and has extensive experience in contact lens fitting. In 2008, Dr. Hatch was asked to serve on the Church of Jesus Christ of Latter-day Saints Church Vision Initiative. This program sends eye care profes-sionals to countries throughout the world.
specialty• Comprehensive Ophthalmology
Roger P Harrie, MD,practices comprehensive ophthal-mology and ocular surgery with a subspecialty in ophthalmic ultra-sound. He is the senior instructor in the ocular ultrasound course at the annual american academy of Ophthalmology meeting. Dr. Harrie has made more than 20 humanitarian trips, mostly training doctors in developing countries in diagnostic and therapeutic techniques.
specialty• Comprehensive Ophthalmology
Mary Elizabeth Hartnett, MD,is Director of Pediatric Retina. She specializes in vitreoretinal surgery and treats and manages adult and pediatric retinal cases. She is now building a pediatric retina center and a pediatric and adult retina clinical practice at the Moran Eye center. She performs surgery at both the moran eye center at the University of Utah and the moran Eye Center at Primary Children’s Hospital.
specialty• Pediatric and Adult Retinal
Diseases and Surgery
Alison Crum, MD, specializes in both oculoplastics and orbital surgery—the recon-struction of the bones around the eyes after traumas, cor-recting drooping eyelids, and aesthetic surgeries, such as eyelid lifts. She also practices neuro-ophthalmology, the study of how the eye connects to the brain, and provides medical and surgical treatments for visual disorders. Her interests include treatment of Graves’ disease and treatment of papilledema.
specialties• Neuro-ophthalmology• Oculoplastics &
Facial Plastic Surgery• Ophthalmology
Kathleen B Digre, MD, is a Past President of the North American Neuro-ophthalmology Society. She specializes in neuro-ophthalmology and evaluates and treats complex visual complaints which can be due to optic nerve or brain disease. Her interests include gender differences in neuro-oph-thalmic disorders, pseudotumor cerebri, ischemic optic neuropathy, temporal arteritis, papilledema, episodic vision loss, headaches and eye pain, diplopia and Graves’ Disease. She has worked with the North American Neuro-ophthal-mology Society and the University of Utah Eccles Library to develop a Neuro-ophthalmology Virtual Educational Library (NOVEL) on the internet at http://novel.utah.edu.
specialty• Neuro-ophthalmology
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Annie Kuo, MD, specializes in diagnosis and treat-ment of acquired and inherited eye diseases in children, including cataract, glaucoma, amblyopia, and lacrimal disorders. She also provides medical and surgical care to children and adults with strabismus.
specialties• Comprehensive Ophthalmology• Cataract Services• Glaucoma• Adult and Pediatric Strabismus• Pediatric Ophthalmology
Nick Mamalis, MD, is Director of the ophthalmic Pathology Laboratory and evalu-ates all specimens submitted to the laboratory. He focuses his clinical practice on comprehensive ophthalmology including cataract and other anterior ocular surger-ies. Dr. mamalis is the editor of the Journal of Cataract and Refractive Surgery and is a member of the Surgery and is a member of the SurgeryAmerican Association of Oph-thalmic Pathologists. He is also Co-director of the Intermountain ocular research center and is performing research in the area of intra-ocular lenses and postopera-tive inflammation. Dr. Mamalis was selected by Cataract and Refrac-tive Surgery Today as one of the 50 tive Surgery Today as one of the 50 tive Surgery Todayinternational opinion leaders.
specialties• Cataract Services• Ophthalmic Pathology• Comprehensive Ophthalmology
Mark D Mifflin, MD, is Moran’s Education Director and the medical Director of the Utah Lions Eye Bank. He specializes in the medical and surgical treatment of corneal and anterior segment eye diseases. His expertise includes all types of corneal transplantation, cataract surgery, and vision correction using lasers, intraocular lenses, and conductive keratoplasty.
specialties• Cataract Surgery• Vision Correction Surgery
(LASIK, Laser, and Non-laser)• Cornea Transplant Surgery
Majid Moshirfar, MD, FACS,is the Director of moran’s cornea and Refractive Surgery Divisions. He specializes in corneal transplan-tation, keratoprosthesis (artificial cornea), management of corneal disorders, cataract extraction, LASIK, inflammatory eye diseases, and other complex procedures of the cornea and anterior segment of the eye. Dr. moshirfar lectures extensively around the country on a variety of vision correction procedures and has become a community spokesperson on the benefits and risks of vision cor-rection surgery. He has appeared in the last three editions of Best Doctors in America.
specialties• Cornea Transplant• Vision Correction Surgery
(LASIK, PRK, LASEK, Phakic IOL, Intacs, CK)
• Cataract Surgery and Intraocular Implants
• Corneal Inflammatory Eye Diseases
• Artificial Cornea
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Robert o Hoffman, MD, is Chief of the Division of Pediatric ophthalmology and eye muscle Disorders. He has special interests in retinopathy of prematurity, ocular genetics, craniofacial disorders, pediatric cataracts, and complicated strabismus.
specialties• Pediatric Ophthalmology• Adult Strabismus
Bradley J Katz, MD, PhD, specializes in neuro-ophthal-mology, cataract, and com-prehensive ophthalmology. He evaluates patients with diseases that affect the optic nerve and diseases of the brain that affect vision and eye movements. Dr. Katz also conducts research in these areas: giant cell arteritis, photophobia and migraine, optic neuritis, and multiple sclerosis.
specialties• Cataract Services• Neuro-ophthalmology
Rachael Jacoby, MD, specializes in medical and surgical diseases of the retina and vitreous. Her primary clinical and surgical interests include retinal detach-ments, diabetic retinopathy, and macular and retinal degeneration.
specialties• Retinal Diseases and Surgery• Macular and Retinal
Degeneration
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16Albert T Vitale, MD, is Director of Moran’s Uveitis Division. He specializes in patients with diseases of the retina and vitreous. He is one of the only oph-thalmologists in the Intermountain West specializing in the diagnosis and treatment of uveitis and other infections and inflammatory diseases of the eye. His research interests include ocular manifesta-tions of systemic diseases, novel therapeutic agents, and new drug delivery systems in the treatment of ocular inflammatory disease, retinal vascular disease, and the pharmacotherapy of age-related macular degeneration. He is one of a few people in the country with dual training in ocular immunol-ogy and inflammatory disease and vitreoretinal surgery. Dr. Vitale is co-author of the definitive text on the subject, with Dr. C. Stephen Foster, entitled, Diagnosis and Treatment of Uveitis.
specialties• Uveitis, Ocular Infections• Retinal Diseases and Surgery
Michael P Teske, MD, is the Director of Vitreoretinal Diseases and Surgery. Dr. Teske specializes in medical and surgical diseases of the retina and vitre-ous. His primary surgical interests include retinal detachment, prolif-erative vitreoretinopathy, diabetic retinopathy, retinopathy of pre-maturity, epiretinal membranes, macular holes, and posterior segment trauma.
specialty• Retinal Disease and Surgery
Judith E A Warner, MD, is Chief of Neuro-ophthalmology, specializing in neuro-ophthal-mology—the study of the eye as it relates to the brain. She evalu-ates complex visual complaints, which can be due to optic nerve or brain disease, and provides treatment for these disorders. Her interests include diplopia, giant cell arteritis, papilledema, optic neuritis, episodic vision loss, idiopathic intracranial hyperten-sion, ischemic optic neuropathy, and unexplained vision loss.
specialty• Neuro-ophthalmology
Geoffrey Tabin, MD, is Co-director of Moran’s International Division. He is a corneal specialist, and in addition to his work in Utah providing corneal, cataract, and refractive care, Dr. Tabin is working to develop eye care delivery in developing countries. Part of his research includes improving cataract and corneal surgery.
specialties• Cataract Services• Vision Correction Surgery
(LASIK, Laser, and Non-laser)
Jean Tabin, MD, provides general vision care and comprehensive ophthal-mology services at the moran Eye Center. Dr. Tabin enjoys working in Moran’s Triage Clinic, treating patients and teaching medical students and residents who are interested in learning more about ophthalmology.
specialty• Comprehensive Ophthalmology
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Barbara M Wirostko, MD, specializes in clinical research and drug development for glaucoma pharmaceutical therapies. Her research interest is in sustained delivery of therapeutics for ocular pathologies and approaching glaucoma through non-intraocular pressure mediated approaches.
specialties• Comprehensive Ophthalmology• Glaucoma
Jeff Pettey, MD, is Moran’s Residency Program Director and specializes in comprehensive ophthalmology, complex cataracts, and anterior segment surgery. He coordinates the teaching and training of medi-cal students, residents, interna-tional observers, and fellows. Dr. Pettey also has an interest in local outreach and in international ophthalmology where he works to develop teaching and training collaborations with programs in developing countries.
specialties• Comprehensive Ophthalmology• Cataract Services
Bhupendra C K Patel, MD, FRCS, FRC, is an expert in the management of disorders involving eyelids, periorbital tissues, the lacrimal system, and facial bones, including fractures. His clinical research interests include thyroid disease, optic nerve disorders, orbital and eyelid tumors, blepharospasm, lacrimal surgery, and facial cosmetic surgery.
specialty• Oculoplastic and
Facial Plastic Surgery
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Lisa ord, PhD, LCSW, is the Director of the ophthal-mology-based Patient Support Program for people with visual impairment and their families. Services in this program include crisis counseling, information and referral services, support groups, and the Orientation to Vision Loss Program.
specialty• Counseling Related to Vision Loss
Donnell J Creel, PhD, is Director of electrophysiology Service at the John a. moran eye center. the electrophysiology Service provides examinations including visually evoked poten-tials, full-field electroretinograms, auditory brainstem responses, electro-oculograms, multifocal electroretinograms, and multifocal visually evoked potentials. These tests quantitate retinal, optic path-way, visual cortical, and brainstem auditory pathway function.
specialty• Electrophysiology
Derek J Sakata, MD, is the Medical Director for Anes-thesia Services at the John a. Moran Eye Center. Dr. Sakata provides and directs anesthesia care for ophthalmic patients before, during, and after surgery. He also has a background in engi-neering and has been involved in medical device design and subsequent company startups. He continues to be involved in research into new medical device designs and drug delivery.
specialty• General Anesthesiology
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Norm A Zabriskie, MD, is the Vice chair and medical Direc-tor of clinical Services and Director of Clinical Operations at the John A. moran eye center. He specializes in the medical and surgical treatment of glaucoma and cataracts. He has a research interest in the genetics of glaucoma.
specialties• Cataract Services• Glaucoma
Marielle young, MD, provides medical and surgical care for children with eye disease as well as adults and children with strabismus. Her clinical expertise includes the evaluation and treatment of amblyopia, strabismus, infantile and developmental cataracts, and nasolacrimal duct obstruction.
specialties• Pediatric Ophthalmology• Adult and Pediatric Strabismus
Alison Crum, MD, specializes in both oculoplastics and orbital surgery—the recon-struction of the bones around the eyes after traumas, correcting drooping eyelids, and aesthetic surgeries, such as eyelid lifts. She also practices neuro-ophthal-mology, the study of how the eye connects to the brain, and provides medical and surgical treatments for visual disorders. Her interests include treatment of Graves’ disease and treatment of papilledema.
specialties• Neuro-ophthalmology• Oculoplastics &
Facial Plastic Surgery• Ophthalmology
Craig J Chaya, MD, specializes in comprehensive ophthalmology with a focus on the medical and surgical manage-ment of cataracts and glaucoma. Dr. chaya also has an interest in international ophthalmology and has worked in Guam, Pohnpei, Ghana, Haiti, Thailand, and Nepal.His research interests include cataract and glaucoma surgery in the developing world.
specialties• Comprehensive Ophthalmology• Cataract Surgery• Glaucoma
Haibo Wang, MD, PhD, Research Assistant Professor of ophthalmology & Visual Sciences.
specialty• Vascular Biology
NEW RESEARCH FACULTyNEW CLINICAL FACULTy
oTHER SPECIALTIES
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Every day, the Greens’ contributions impact ophthalmic care at the Moran Eye Center—through the work of inaugural chair-holder Dr. Alan Crandall and at the Val A. and Edith D. Green Foundation Clinical Research Center, where all patients who enroll in Moran’s Center for Translational Medicine (CTM) research are welcomed and examined.
The family’s relationship with Moran stretches back a few decades when age-related macular degeneration (AMD) first struck Mr. Green. Because his vision was so compromised, he could no longer drive and had to take an early retirement from a highly successful career with The Coca Cola Company. “While the doctors at Moran were able to help slow the progression of the disease, they couldn’t prevent it,” says their son, Val Green, of Park City, Utah. “Despite that, the team at Moran built a real desire in my dad to someday help beat AMD. They gave him hope. My mom also had challenges with her vision and ended up having a cornea replaced. Thanks to Drs. Mano Swartz and Alan Crandall and Moran’s Patient Support Program, her vision was fine for years after that.”
Val A. and Edith D. Green Foundation
Three Generations of
When Val A. and Edith D. Green established their Presidential Endowed Chair in Ophthalmology at the University of Utah in 1997, it was with a generosity of spirit that has carried on through the generations.
GIVING
The Greens’ legacy now thrives in their children and grandchildren who are making a difference through the foundation established by Val and Edith’s estate. “My dad loved the Layton area and the Wasatch Front, and he wanted to really help people here,” he notes. “We set the foundation up together with the intention of making it a generational thing, so my entire family is involved, including my wife Elizabeth, my sister Hollie, and her son Brodie. My oldest son, Aaron, is already on the grants board, and Matthew, the youngest, is a photographer who helps document some of our projects. Our causes are fairly eclectic, so there’s a lot of research to do, and it’s important that the whole family knows what’s going on.
“When it comes to Moran,” he says, “we have a long and trusting relationship, so we all know that whatever the needs are, they are worthy. I don’t hesitate to tell people facing vision challenges, ‘this is where you have to go—there is no better place in the country—so put your eyes in their hands.’”
“…the team at Moran built a real desire in my dad to someday help beat AMD. They gave him hope.” —Val Green
Val A. and Edith D. Green
Dr. Crandall has always remembered his father’s philosophy. Whether in his pioneering work in international outreach at Moran or his day-to-day interactions with patients and students, his outlook remains the same: “Every little bit you can do to help can make a big di�erence in the long run. I really believe that. Every little kindness comes back.”
New Presidential Endowed Chair in Ophthalmology Dr. Crandall brings a rich and storied legacy to his newly appointed position as the inaugural holder of the Val A. and Edith D. Green Presidential Endowed Chair in Ophthalmology. A highly respected surgeon, educator, and humanitarian, he holds the titles of Senior Vice Chair, Director of Glau-coma and Cataract, and Co-director of Moran’s International Division. Among other notable honors, he is a past presi-dent of the American Society of Cataract and Refractive Surgery (2010).
History-making Friendship with Randall J Olson, MDDr. Crandall’s path to the Moran Eye Center began at the University of Utah where he �rst met now-CEO Randall J Olson, MD. As medical students, the two forged a bond, but had no idea what lay ahead in terms of the history they would create over the next few decades. A�er completing medical school, each went his own way for residencies and fellow-ships. Dr. Olson returned to Salt Lake City to become a one-person division of ophthalmology at the U.
COMES BACKDr. Alan S. Crandall honored as the Inaugural Holder of the Val A. and Edith D. Green Presidential Endowed Chair in Ophthalmology
As the son of one of Utah’s first ophthalmologists, Dr. Alan S. Crandall recalls accompanying his father to the
original St. Mark’s hospital in Salt Lake City where some of his father’s patients paid him on the barter system.
“It wasn’t unusual to receive a chicken instead of cash. My father’s philosophy was that he would treat every-
body exactly the same way. As far as I could tell, he had no prejudice against anything other than stark stupidity.
He was true to his word—he worked hard and loved what he did.”
Every Little Bit of Kindness
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back. As we now do worldwide, we have also trained their doctors by bringing them here to Moran. �ey are then able to go back to do the work and to train other doctors.” Because of these and other heroic e�orts, Dr. Crandall points out that the rate of curable blindness has dropped and is now decreasing every year in several third-world countries for the �rst time in history.
“I am honored that the Greens and the University of Utah feel that they can count on me to deliver excellent care, stay on the cutting edge, and continue to spread Moran’s mission of curing blindness in every sphere—locally and around the world,” Dr. Crandall says. “To me, it also means they recognize that I’m a hard worker, and I’m making a di�erence.”
Among many other acts of giving, Dr. Crandall uno�cially initiated Moran’s International Outreach Program. It all began in the late 1970s, a few years a�er Alex Haley’s best selling book, Roots came out. “One of my patients, Gladys Richardson, read it and wanted to �nd out more about her family’s history in Africa,” he says. “She went to Ghana, and when she came back, she talked to me about the dire need for schools and treatments to help reverse the epidemic of blindness caused by cataracts. So I said, what the heck, let’s go over there and see what we can do.
“We made contact with �e Komfo Anokye Teaching Hospital (KATH) in Kumasi, in central Ghana. We started slowly, with just ten to ��een cataract surgeries. At the time, that was what they were able to do in a two-or three-day period. Every year since, we’ve gone
“ALL IT TOOK WAS A CALL FROM RANDY ASKING ME TO JOIN HIM BACK HERE, AND THAT WAS IT.”
—Dr. Alan S. Crandall
“I still remember our first Christmas party. Our division consisted of six people, including three doctors. I brought my boom box in, and we listened to Willie Nelson’s Christmas album. It was great.”
—Dr. Alan S. Crandall
Meanwhile, Dr. Crandall joined the faculty at the Scheie Institute, University of Pennsylvania. He says he enjoyed the Ivy League, but Salt Lake City and its mountain-ringed landscape still called to him. “All it took was a call from Randy asking me to join him back here, and that was it,” recalls Dr. Crandall. I still remember our �rst Christmas party. Our division consisted of six people, including three doctors. I brought my boom box in, and we listened to Willie Nelson’s Christmas album. It was great.” Dr. Crandall says he also felt more at home in Utah sporting his growing collection of bolo ties, which he started wearing in Pennsylvania once he �gured out that he was “not the bow-tie type.”
Eventually, the division became a department. “Our goal was to deliver �rst-rate care and then to expand to become an international center for research. So, we grew with a lot of hard work and a bit of luck. �e fact that John A. Moran also wanted to give back and attach his name to our cause changed everything.” Today Moran has become a global leader in ophthalmology.
Dr. Alan S. Crandall
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“Every little bit you can do to help can make a big difference in the long run. I really believe that.”
—Dr. Alan Crandall
Dear Friends and Colleagues:
I have been dying to make this announcement for quite a while, but had to wait until it was official. One of the highest honors that can be awarded a faculty member is to be appointed as a presidential endowed professor, which is the highest of the Endowed Chairs at the University of Utah. Well, it is my distinct honor and pleasure to announce that Alan Crandall, after years of amazing service in every aspect of his career, is now officially the Val A. and Edith D. Green Presidential Endowed Chair in Ophthalmology! Please join with me in celebrating this distinct honor and thanking this remarkable individual for all he has done for the John A. Moran Eye Center!
Alan, you are the best!!
Sincerely, Randall Olson, MD CEO, JMEC
Dr. Olson sent this email to all Moran employees. It shows the great friendship and admiration he has for Dr. Crandall:
Dr. Crandall in surgery
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Debilitating vision problems know no borders. they affect every population and ripple through economies both international and local. that’s why Moran’s outreach Programs aim to reach around the world as well as down the street. Close to home in Salt Lake City, Moran surgeons, medical technicians, and staff donate their services to provide surgery to people in need at Moran’s own surgical facilities one special day each year.
Charitable Saturday Surgery Day at the Moran Eye Center, originally conceived in 2007 by two
fourth-year medical students, is now an established community service with a monumental effort
behind it. one Saturday each year, after months of planning and preparation, Moran staffs up with
40 volunteers, including secretaries, scrub techs, anesthesiologists, technicians, residents, fellows,
nurses, surgeons, and our guest relations specialist to welcome 12 patients, many of whom have
been screened and diagnosed through Moran’s monthly outreach work at the fourth Street and
Maliheh Clinics in Salt Lake City and the People’s Clinic in Park City.
Charitable Saturday Surgery Day
Moran’s Cynthia Johnston, pre-and post-op nurse, readies Leitha Harvey for surgery
Cha
ritab
le
“Mrs. Harvey is a prototype of
many of the patients I see,” says
Moran’s Bradley J. Katz, MD, PhD,
who specializes in cataract surgery
and neuro-ophthalmology and is
one of the surgeons who donates
his services on Surgery Day and
throughout the year at local clinics.
“She is 64, doesn’t yet qualify for
Medicare or Medicaid. She works,
but doesn’t make enough for health
insurance. Even if she did, cataracts
are an elective surgery not always
covered by insurance.”
Not surprisingly, the need for help is
greater than the capacity, so Moran
has scheduled a second surgery day
for October 2013.
Because Moran is the only major aca-
demic ophthalmology center for the
Intermountain West, working at Fourth
Street Clinic for the homeless provides
a unique educational opportunity for
medical students, residents, and
fellows to see pathology that they
would not necessarily see. They pro-
vide volunteer services one Tuesday
evening per month for as many as 25
patients needing eye care.
“While it sounds exotic to travel to
Nepal,” says Albert T. Vitale, MD, who
specializes in retinal diseases and
uveitis and is the Medical Director for
the Moran Eye Clinic at the Fourth
Street Clinic, “plenty of people right
down the street need eye care. Our
work serves an unmet need for the
uninsured and marginalized. It also
gives residents an opportunity to
perform surgeries and expands the
Moran Eye Center’s mission of service
at home.”
“I started crying,” says Leitha Harvey,
about her reaction to having cataract
surgery. “My gosh…everything is so
bright. I’m thrilled; I’m energized; I
have a new lease on life—I’m just so
grateful they gave me back my vision.”
sur
gery
Day
“My gosh…everything is so bright. I’m thrilled; I’m energized; I have a new lease on life—I’m just so grateful they gave me back my vision.” —Leitha Harvey
Last year, Leitha Harvey was one of
those deserving patients. A sixty-
four-year-old massage therapist
suffering from advanced cataracts,
she is employed but uninsured and
living with her son. By the time she
was able to get cataract surgery at
Moran, this is how Leitha functioned:
“Co-workers had to clock me in and
out and write out the names of my
clients. I could only see to drive in
the daytime with one eye covered. I
went to work during daylight hours,
but had to come home after dark,
so I covered my right eye to see with
my left and prayed that no one was
coming! I have to say that I crossed
over lines a few times. I’m just really
grateful for the team of workers here
and the people who are willing to
donate to this cause. I didn’t think it
was available for someone like me. I’m
not from Nepal or Africa or the Indian
Reservation, but I find myself in a
position that I need help.”
Dr. Derek J. Sakata, standing; Dr. Bradley J. Katz and surgical team
Dr. Bradley Katz and Leitha Harvey
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ANDY’S
“You may encounter many defeats, but you must not be defeated. In fact, it may be necessary to encounter the defeats, so you can know who you are, what you can rise from, how you can still come out of it.” —Maya Angelou
Unexpected Pit Stop
Mike Nish, Andy Nish, and Moran’s Dr. Paul Bernstein
An Innocent Game of Dodge Ball Watching fourteen-year-old Andy Nish cross the �nish line for second place in the 2012 World Junior Karting Cham- pionship at Miller Motorsports Park, you would never know that he accom-plished this feat with a macular hole and detached retina—and neither did Andy! Just as shocking, Andy had been functioning with this catastrophic vision injury for almost two years be-fore he sought help.
�e answer to the obvious question, “How did Andy not know?” is a combination of his utterly youthful resilience and his reticence to complain. “If he did complain, I didn’t hear it,” says Andy’s dad, Mike Nish, “nor did his mother.” It wasn’t until Mike asked, “How come your eye is so red?” and heard Andy’s jaw-dropping reply, “cause I can’t see out of the other one,” that they �nally sought treatment. Recalling
“We can ask other patients to lie face
down for a week, but it is very hard to do
that with an active teenager.” —Dr. Paul Bernstein
past accidents, they realized that Andy had been slammed in the side of the head with a dodge ball two years prior, but because the incident was so long ago and the problem had gone undetected, the injury gradually degenerated to where Andy nearly lost all vision in his le� eye.
Diagnosis “�e severity of the injury to the retina, the hole torn directly in the macula, and complex scar tissue reaction made Andy’s injury signi�cantly complicated and challenging,” says Moran Eye Center’s world-renowned retinal specialist, Paul S. Bernstein, MD, PhD, who specializes in vitreoretinal diseases and surgery, retinal biochemistry, and macular and retinal degeneration.
�e macula is the part of the retina that is responsible for our central vision and ability to see color and �ne detail when looking directly at an object. “Macular holes from trauma are not common in children, but when they occur, they are very severe,” says Dr. Bernstein.
Surgery To heal Andy’s eye, Dr. Bernstein �rst sewed a scleral buckle, a plastic band, around the equator of the eye, which “feels like getting hit in the eye with a pool cue,” remarks Andy. �is relieves tension on the retina and pushes the sclera toward the middle of the eye toward the tear until it heals. Several weeks later, he performed a state of-the-art small-incision vitrectomy to remove the vitreous and scar tissue. Looking through a microscope through Andy’s dilated pupil, Dr. Bernstein used tiny 25-gauge needles to go in through three ports: “One pumps �uid in, one puts a light source in, and one is the actual instrument,” he explains. Several weeks a�er the vitrectomy, Dr. Bernstein �lled the hole in Andy’s macula with silicone oil, which acts like a shock absorber and pushes the retina back in place, allowing the hole to close. �e scleral buckle and silicone oil will stay in Andy’s eye forever.
Tailoring Andy’s Care Dealing with an active young person who plays basketball, wrestles, and races Karts poses a di�erent kind of challenge. “We can ask other patients to lie face
Andy getting a post-surgery checkup with Dr. Bernstein
Andy in the winner’s circle
The Race to Recovery is Longer than Expected, but the Driver Remains Focused “I thought I would have one surgery, and it would be fixed,” says Andy. “My advice to other kids about having to stop the thing they are passionate about—stay as involved as much as you can. Even though I can’t race yet, I coached a five-year-old boy at the track and helped my little sister with her championship race; I can’t wrestle yet, but Dr. Bernstein says I can be a wrestling manager.”
Yet, in treating an undaunted teenager who aspires to follow in his father’s footsteps, who is as tough and resilient as the 2500-horsepower Nitro Hemi engine that powers his family’s Royal Purple Streamliner, and who has almost completely lost the vision of one eye—the biggest challenge for Dr. Bernstein may not be healing Andy’s eye. Indeed, it may be how to steward the transi-tion of a feisty, driven adolescent as he evolves, through introspection, to adopt a very mature, life-changing philoso-phy—that he may have to reformulate his dream.
down for a week, but it is very hard to do that with an active teenager,” says Dr. Bernstein. “While Andy is a very good patient, he is still very limited in his activities. He always wants to know what he can do and when he can go back to sports…to car racing.”
And car racing is in Andy’s blood. Among the land-speed racing community, the name Nish conjures instant recognition. Terry Nish, Andy’s grandfather, and his three sons, Mike (Andy’s dad), Jeff, and T.J., often tout themselves as the world’s fastest family, holding thirteen records set at the Bonneville Salt Flats—all four are in the 300 MPH Club. This year, the Nishes hope to break their own land-speed record, reaching 425 MPH in their “Royal Purple Streamliner.” It is Andy’s dream to follow in their “racetracks.”
“When I get in the car, I’m completely focused,” says Andy. “I run the track through my mind. And when the green flag drops, it is an adrenalin rush. I never feel scared; it is not a priority. I just want to beat anyone who is in front of me. But racing is not easy,” he explains. “The concentration is mentally and physically exhausting. You have to constantly think and strategize about a maneuver two laps ahead.” Andy wants to drive the Streamliner—a hot-rodder’s dream that goes over 400 mph. “That’s what I’ve wanted to do since I was two,” Andy grins. “Drive.”
Andy has endured several more surgeries to remove scar tissue that tugs at his retina, and he has had a cataract removed. Now, “the macular hole is closed, the retina is reattached, and he has pretty good peripheral vision,” says Dr. Bernstein. “But Andy has lost central vision, which he will never completely get back.” “When I close my good eye, I can see your outline,” says Andy. “But I can’t see detail.”
“I’m amazed every time Andy comes in,” says Dr. Bernstein. “We just want him to have a very functional eye, very useful for the rest of his life.”
“My dream is to race Formula One,” states Andy, “if I can’t do that, I’ll be involved in whatever way I can—I stay involved because I need to stay involved.”
The Nish family’s Royal Purple Streamliner
Andy in Kart #82 takes the lead
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Balamurali K Ambati, MD, PhD, MBAProfessor of Ophthalmology and Visual Sciences and Adjunct Associate Professor of Neurobiology and Anatomyspecialtiesocular angiogenesis and corneal research
Alessandra Angelucci, MD, PhDAssociate Professor, Ophthalmology and Visual SciencesspecialtyVisual Cortex Circuitry and Function
R E S E A R C H T E A M 2013m o r a n e y e c e n t e r
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Wolfgang B Baehr, PhD
Professor and Director, Michael M. Wynn Center for Inherited Retinal Diseases; Ralph and Mary Tuck Professor of Ophthalmology and Visual SciencesspecialtiesPhototransduction, the Retinoid Cycle, and Membrane Protein Transport in Photoreceptors; Biochemistry, Molecular and Cell Biology
Paul Bressloff, PhD
Adjunct Professor, Ophthalmology and Visual Sciences; Professor of Mathematicsspecialtymodeling of Visual cortex
Paul S Bernstein, MD, PhD
Director of Clinical Research and Associate Director of Research; Mary H. Boesche Professor of Ophthalmology and Visual SciencesspecialtiesVitreoretinal Diseases and Surgery; Retinal Biochemistry; Macular and Retinal Degeneration
Donnell J Creel, PhD
Research Professor, Ophthalmology and Visual Sciencesspecialtyelectrophysiology
Jeanne M Frederick, PhD
Research Associate Professor, Ophthalmology and Visual SciencesspecialtyRetinal Cell and Molecular Biology
Margaret DeAngelis, PhD
Associate Professor of Ophthal-mology and Visual SciencesspecialtyGenomic Convergent/Systems Biology: approaches in an effort to pinpoint disease causality in age-related macular degeneration, diabetic retinopathy, and rare ocular diseases.
yingbin Fu, PhD
Assistant Professor of Ophthal-mology and Visual SciencesspecialtiesMacular and Retinal Degeneration; Gene Therapy; Phototransduction
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Sabine Fuhrmann, PhD
Associate Professor, Ophthalmology and Visual SciencesspecialtiesOcular Development; Retinal Pigment Epithelial Cell Biology
Werner Gellermann, PhD
Adjunct Professor, Ophthalmology and Visual Sciences; Research Professor, PhysicsspecialtySpectroscopy of Living Human tissue
Helga E T Kolb, PhD
Professor (Emeritus), Ophthal-mology and Visual SciencesspecialtyRetinal Anatomy
David Krizaj, PhD
Associate Professor, Ophthal-mology and Visual SciencesspecialtiesRetinal Neurobiology; Calcium Regulation; Glaucoma
Mary Elizabeth Hartnett, MD
Professor, Ophthalmology and Visual SciencesspecialtyRetinal Angiogenesis Relating to Retinopathy of Prematurity and Age-related Macular Degeneration
Bryan W Jones, PhD
Research Assistant Professor, Ophthalmology and Visual SciencesspecialtyRetinal Degeneration Disorders: how those diseases affect the intrinsic retinal circuitry, including the implications for rescue of vi-sion via gene therapy and retinal bionic or biological implants; Retinal Neurotransmission and Neurocircuitry; Metabolomics: for application in understanding physiology and medicine for drug development
Gregory S Hageman, PhD
John A. Moran Presidential Professor, Department of Oph-thalmology and Visual Sciences; Executive Director, Moran Center for Translational MedicinespecialtiesThe Genetics and Assessment of Pathways Involved in the Etiology of Age-related Macular Degenera-tion; Retinal Cell Biology
Building bridges from research to patient careg ges fges fg patient ca
Bradley J Katz, MD, PhD
Associate Professor, Ophthal-mology and Visual SciencesspecialtiesNeuro-ophthalmology; Diseases of the Optic Nerve; Comprehen-sive ophthalmology and Surgery
Julia Kleinschmidt, PhD, LCSWProfessor (Emeritus), Ophthal-mology and Visual SciencesspecialtyOrientation and Support Services for international ophthalmolo-gists training under the moran Eye Center’s International Out-reach Division
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Ning Tian, PhD
Professor, Ophthalmology and Visual SciencesspecialtyRetinal Neurobiology
Monica Vetter, PhD
Adjunct Professor, Ophthalmology and Visual Sciences; George and Lorna Winder Professor of Neuroscience; and Chair, Neurobiology and AnatomyspecialtiesRetinal Development, Glaucoma
Haibo Wang, MD, PhD
Research Assistant Professor of Ophthalmology and Visual SciencesspecialtyVascular Biology: abnormal vessel growth implicated in pathological neovascularization in age-related macular degenera-tion, retinopathy of prematurity, and diabetic retinopathy
Richard A Normann, PhD
Professor, Ophthalmology and Visual Sciences; Distinguished Professor of BioengineeringspecialtyArtificial Vision/Neural Prosthetics
Edward M Levine, PhD
Associate Professor, Ophthalmology and Visual SciencesspecialtyRetinal Neurogenesis and Regeneration
Nick Mamalis, MD
Professor, Ophthalmology and Visual Sciences; Co-director, Intermountain Ocular Research CenterspecialtiesOcular Pathology; Comprehensive Ophthalmology; Intraocular Lens Research; Postoperative Inflammation
Robert E Marc, PhD
Director of Research and Distin-guised Professor of Ophthal-mology, John A. Moran Eye Center; Cal and JeNeal Hatch Presidential Endowed Chair in Ophthalmology and Visual SciencesspecialtiesRetinal Neurotransmission and Neurocircuitry; Metabolomics
R E S E A R C H T E A M 2013m o r a n e y e c e n t e r
Jun yang, PhD
Assistant Professor, Ophthal-mology and Visual SciencesspecialtiesCell Biology of Photoreceptors and Retinal Diseases
Barbara M Wirostko, MD
Clinical Adjunct Associate Professor, Ophthalmology and Visual SciencesspecialtiesGlaucoma; Drug and Device Development
Liliana Werner, MD, PhD
Associate Professor, Ophthal-mology and Visual Sciences; Co-director Intermountain Ocular Research CenterspecialtyOcular Biodevices Research including different intraocular lens designs, materials and surface modifications, and interactions with ocular tissues.
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While it is well known that glaucoma, macular degeneration, and retinitis pigmentosa can cause blindness, many people do not know that 10-15 percent of all blindness in the US is a result of inadequately treated uveitis. “That’s key,” states Dr. Vitale. Uveitis is inflammation of the uvea, the middle layer of the eye, consisting of the iris, choroid,
and ciliary body. Any form of uveitis may be serious and may be a symptom for other serious conditions. “Forty-five to fifty percent of patients will have permanent visual impairment from not being adequately treated,” says Dr. Vitale. “The impact of that blindness is significant because it frequently affects people in their productive prime. So, it is essential to make a diagnosis and to treat uveitis effectively and adequately—to get the inflammation under control to prevent the ocular structural damage to the eye that leads to permanent visual impairment.”
And this is the crux of the disease: “Uveitis can be challenging to diagnose because of its complexity. It can occur by itself or as a feature of an underlying disease,” says Dr. Vitale. “Uveitis is not one disease—it is about 30 diseases.”
The book presents a unique philosophy: “Our mission is remission—a complete intolerance to chronic, even low-grade intraocular inflammation—with no relapse.” The text stresses that physicians follow a comprehensive approach to diagnosing the underlying cause of the patient’s uveitis. This includes collaborating with a trained and truly expert chemotherapist or ocular immunologist about how to use immunomodulatory medications so that the patient does not experience any significant drug-induced side effects. “Use whatever you need, but don’t subject the patient to unnecessary medications just to induce a remission of these diseases—this is a key concept—however you can do that,” stresses Dr. Vitale.
“I’m not against any one therapy, but the approach needs to be individualized to the patient, to their disease, and to what they can or cannot tolerate. It requires knowing the patient very well, medically, ocularly, and personally,” he continues. “If a patient tells you, ‘You know what, I’m going to become a homicidal maniac if you give me systemic steroids,’ I probably won’t do that.”
OUR MISSION IS REMISSION
Second Edition
Diagnosis and Treatment of Uveitis
As the ophthalmic community is rife with uveitis texts and references, how does one become excited about yet another tome…and the second edition at that?
The extraordinary commitment and conscious philosophy of one Moran physician
may be the answer. Please join Moran and the worldwide medical community in
welcoming the second edition of Dr. Albert T. Vitale’s definitive textbook, Diagnosis
and Treatment of Uveitis. The book, noted for its “encyclopedic organization,” was
published in 2012 with co-author Dr. C. Stephen Foster. Dr. Vitale is one of the
only ophthalmologists in the Intermountain West specializing in the diagnosis and
treatment of uveitis and other infections and inflammatory diseases of the eye.
He is also one of a handful of people in the country with dual training in ocular
immunology and inflammatory disease as well as vitreoretinal surgery. He is the
only provider of such expertise in the Intermountain West.
Not only is the book clear about its philosophy, it is comprehensive in scope, offering six sections, 83 chapters, and over 1,200 pages. “There are other books, which are great textbooks, but this is very user-friendly—very readable. I think in broad categories…you’ve got all this information available…you can look here for specifics, in chapters,” explains Dr. Vitale.
“You have to stay in the hunt: if you don’t at first come up with a diagnosis, always evaluate, reassess, and rethink the patient’s response to your treatment. If something isn’t working, try something different to gain control of the inflammation without pro-ducing untoward side effects,” he stresses.
“I believe that we are on the planet to help each other. There is much more that binds us together than separates us if you are awake and attentive to it,” says Dr. Vitale. “I see that every day in taking care of my patients…I really do. They just teach me so much. It is humbling. It is a real privilege to be a physician.”
“I’m totally awed and humbled
by the way in which many of my
patients handle tremendous adversity
and the trust that they put in me. The
burden that they manage is almost
unthinkable sometimes.” —Albert T. Vitale
VIT
ALE
Albert T. Vitale MD, has incorporated his research interests into clinical practice and is focused on novel drugs and delivery systems for the treatment of ocular inflammatory disease, age-related macular degeneration, and diagnostic and therapeutic vitreoretinal surgery in the management of uveitis, pediat-ric uveitis, and the interface between ocular inflammatory disease and age-related macular degeneration.
In addition, he is involved in the delivery of comprehensive and sustainable retinal care in the developing world through the Division of International Ophthalmology at the Moran Eye Center and ORBIS. He also works with the indigent and underserved in Salt Lake City, serving as Medical Director for the Moran Eye Clinic at the Fourth Street Clinic. Dr. Vitale is committed to education, not only among residents and fel-lows at the Moran Eye Center, but nationally and internationally, serving as contributing editor for several American Academy of Ophthalmology publications.
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�ere is huge pressure for scientists to report positive �ndings, and historically,
negative results have been harder to publish. However, corrective science is part of the
process—and needs just as much attention. —Bryan W. Jones, PhD
Moran Researchers Upend Prevailing Theories about
RARE CHILDHOOD DISEASE
A commitment to ongoing, intensive vision research with the potential to change millions of
lives sets the Moran Eye Center apart. Keeping Moran at the forefront are creative researchers
like David Krizaj, PhD (pronounced KREE-zhai); Peter Barabas, PhD; Aihua Liu, PhD; Wei Xing;
Ching-Kang Cheng, PhD; Zongzhong Tong, PhD; Carl B. Watt, PhD; Bryan W. Jones, PhD; Paul
S. Bernstein, MD, PhD; and their willingness to question assumptions behind accepted theories.
Case in point: For years, vision scientists believed that a lack of very long-chain fatty acids (VLC-PUFAs) in photoreceptor cells caused blindness in children with Stargardt type 3 retinal degeneration. Stargardt, an incurable eye disease, is a form of macular degeneration that strikes about one in ten-thousand children between the ages of six and twenty. The severity and progression of the disease varies widely, but vision loss is most intense in the macula, in the center of the retina. Some peripheral vision may remain, but visual acuity can decline to 20/200 or slightly worse, rendering children legally blind.
Three types of Stargardt are caused by three different gene mutations: ABCA4, CNGB3, and ELOV4. Scientists have long thought that type 3, the rare and autosomal dominant form of the disease, is caused by defects in the gene ELOVL4. (Moran’s Dr. Paul Bernstein, retinal specialist and professor of ophthalmology and visual sciences, was one of the original discoverers of the ELOV4 mutation, having characterized it in a Utah family.) However, ongoing studies and results regarding Stargardt type 3 have actually been somewhat contentious. According to Dr. Krizaj, “The prevailing theory about long-chain fatty acids has always been up for dispute because, for one thing, scientists were unable to generate an animal model of the disease—mice in which ELOVL4 was knocked out did not survive.”
To Dr. Krizaj and his team, the challenge was academically fascinating as well as motivating. “While the focus in our lab is on photoreceptor cells—mainly their physiology—we thought we had a shot at providing a more definitive theory as to what the mechanism underlying this devastating disease might be,” he explains. “If we can understand its causes, we can possibly find treatments to first delay and then maybe prevent it from manifesting.”
Engineering Change By actually breeding a better mouse, the researchers disproved the prevailing theory. Our models lacked ELOVL4 only in their photoreceptor cells, allowing the mice to survive, but with the fatty acids in those cells reduced up to 90 percent. This allowed them to test directly whether loss of very long-chain fatty acids replicates vision loss in children with Stargardt disease. Electrophysiological and behavioral testing of day and night vision in the mice showed that sight was not affected despite the dramatic reduction in very long-chain fatty acids in photoreceptor cells. The group published its findings in PNAS online, March 11, 2013. Peter Barabas, PhD, a postdoctoral fellow in Dr. Krizaj’s group, is the first author on the study.
As a result, the research community experienced a “one-step-back” moment—which, according to Dr. Krizaj, “means that a set of proposed treatment strategies can be set aside, and we can start thinking of new possibilities. One is that mutated proteins escaping from the endoplas-mic reticulum are aggregating in the cytoplasm, a jelly-like substance in the cell, and resulting in large deposits of mutated and normal proteins. This is almost like causing photoreceptor cell death by blocking intracel-lular traffic and clogging the cells’ drains,” Krizaj notes.
Going Forward While the published study constituted a breakthrough moment, mouse models are by no means perfect replications of human Stargardt type 3. Moran researchers have a solution. “Humans rely on cone photoreceptors much more than rods during the daytime,” explains Dr. Krizaj. “Mice are basically nocturnal, so they have just a small percentage of cones. Our mouse models are closer replicas of the human Stargardt disease. We have submitted a grant with Dr. Bernstein to the Foundation Fighting Blindness and will eventually go to the National Institutes of Health to pursue the grand question: what is the best way to first delay and then prevent Stargardt type 3?”
A scan of a patient’s retina with Stargardt Disease, or fundus �avimaculatus, an inherited form of macular degeneration that causes progressive vision loss and blindness. �is retinal scan is projected on top of the retina of a mouse model in red and green, designed to let scientists at the Moran Eye Center study some of the mechanisms of the disease.
Photo credit: Bryan William Jones, PhD
Paul S. Bernstein, MD, PhD, David Krizaj, PhD, Bryan W. Jones, PhD, and Peter Barabas, PhD
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Premature babies born weighing less than 2-3/4 pounds have always been at risk for ROP because the retina is not fully developed until full term. But because technology to save ever smaller and younger preterm babies has developed throughout the world, ROP has become a leading cause of infant and childhood blindness worldwide. “I’ve been examining babies and treating them with laser and surgery for over 20 years. �e gestational age of preterm infants who survive to develop ROP has become younger, and the appearance of ROP has changed with this. However, in developing countries outside the US, older and larger preterm infants
Retinopathy of prematurity is a vision-threatening disease caused by abnormal development of the retinal blood vessels, whereby instead of growing into the retina, the blood vessels start to grow into the vitreous gel where they bleed and form scars. Retinopathy of prematurity occurs only in premature infants and is the subject of a Medical Progress Report by Dr. Hartnett and co-author John Penn, PhD, of Vanderbilt University, published in the New England Journal of Medicine, December 27, 2012.
Mary Elizabeth Hartnett, MD
are developing ROP in part because the resources to regulate oxygen are lacking. Many of these infants are developing ROP similar to what occurred in the US in the 1950s,” she says.
“When ROP was �rst recognized in the US, it was thought to manifest because of the amount of oxygen that was being given to preterm babies—100 percent in some cases—which injured the babies’ newly developing endothelial cells. But with the ability to regulate oxygen to preterm infants, our perspective has since changed: initial descriptions may have represented a di�erent form of ROP than we see now
M������ P������� R�����:
S H E D D I N G
New Light on Retinopathy of
Prematurity
If there is any way to avoid the need for vitreoretinal surgery on a preterm baby, Dr. Mary Elizabeth Hartnett is
determined to �nd it. “�e safe area to enter the eye of a premature baby is less than a millimeter wide. Outside of that, you could
damage the tiny lens or injure the retina, which could lead to inoperable retinal detachment,” she says. “Obviously, the stakes are
incredibly high.” And yet, there have been cases in which Dr. Hartnett, who specializes in pediatric and adult retinal diseases and
surgery at the Moran Eye Center, has had to operate on preterm infants whose gestational and chronologic age combined was
under term birth. �ese infants were experiencing retinal detachments from retinopathy of prematurity (ROP). Fo
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PEDIATRIC RETINA CENTER AT MORAN Whether an infant experiences surgery for the most progressive stages of ROP or develops a milder form that eventually resolves on its own, infants with ROP are considered to be at higher risk for developing certain eye problems later in life, such as retinal detachment, myopia (nearsightedness), strabismus (crossed eyes), amblyopia (lazy eye), and glaucoma. In many cases, these eye problems can be treated or controlled, but as Dr. Mary Elizabeth Hartnett points out, “Doctors and parents must be constant advocates for these kids. It is so important.”
The Pediatric Retina Center at Moran is equipped to diagnose and treat these and myriad other conditions, including rare situations specific to children. Moran’s highly specialized team has the capacity to perform vitreoretinal surgery and offers diagnostic testing, such as electroretinography (which measures the function of the retina since very young children can’t read a chart), consultations, and visual rehabilitation. The team also consults with people who can’t make it to the clinic or with their doctors. The center has the potential to become a hub of services and resources in the inter-mountain region.
The Pediatric Retina Center at Moran can also be of particular help in small or rural areas that may not have pediatric retina specialists by bridging the gap between what doctors and patients know about pediatric retinal conditions and what can be done, including vetting the best websites, providing reliable information and images, and consulting with doctors nationwide.
that oxygen is regulated,” Dr. Hartnett explains. “Rather than injuring already developed retinal vessels, we see that normal retinal vessel development is slowed down, and instead, vessels grow abnormally from the retina into the normally clear gel that �lls the back of the eye. �ese vessels are fragile and can leak, causing bleeding into the eye. As a consequence, scar tissue may develop and pull the retina loose from the eye’s inner surface. In severe cases, this results in loss of vision.
“It is really di�cult to research ROP. In the infant, especially a premature one, taking any �uid from the eye is extremely risky and can lead to blindness. And of course, preterm infants don’t have a lot of blood, so taking too much blood is avoided. Consequently, we study ROP by using mouse models,” Dr. Hartnett
explains. “From the 1940s–60s, there was a mouse model of oxygen-induced retinopathy using high oxygen to examine the cellular and molecular mechanisms that drive the progression of pathologic changes in ROP. But the mouse model really doesn’t re�ect most of the ROP we see in the US today. A number of technical advances have occurred so that we can regulate and monitor the oxygen levels of babies, but in a disease where we are limited as far as what we can do in the human infant, we really need to use relevant animal models to be able to study the disease. �at was the �rst part of our article,” she says. “In the second part, we described various pathways that appear to be important using a rat model developed by John Penn that may lead to treatments for ROP.”
As the article points out, this is a �eld in �ux, with a number of dilemmas. Some treatments, such as anti-vascular
endothelial growth factor (VEGF) injections that seem to help may also have adverse e�ects (this topic is explored in recently published papers from Dr. Hartnett’s lab). “What makes it hard is that there are so many things going on with preterm babies. We are dealing with issues of development as well as the disease,” she notes. “Sometimes factors, such as VEGF, that cause pathologic features of ROP are also important in the development of the preterm infant. As we understand more of what’s going on in preterm babies with ROP, we will be able to better treat the disease, improve visual development, and hopefully, avoid the need for surgery.”
Mary Elizabeth Hartnett, MD, Professor, Department of Ophthalmology and Visual Sciences at the Moran Eye Center,
was awarded the Honor of Silver Fellow, 2013, by the Association for Research in Vision and Ophthalmology for her work as
a role model and mentor for people pursuing careers in vision and ophthalmology research. She was also recently selected
for a prestigious post with the National Eye Institute at the National Institutes of Health as Chairperson to the Diseases and
Pathophysiology of the Visual System Study Section at the Center for Scientific Review, 2013. As chair, she will be leading
one of the main translational eye study sections that reviews grants for the National Eye Institute.
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S E C o N D y E A R
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Luis Santiago-Caban, MD
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Adam Jorgensen, MD Brian Stagg, MD Russell Swan, MD
Zachary Joos, MD Trent Richards, MD Brian Zaugg, MD
T H I R D y E A R
Valli Muthappan, MD
Ronald Hobbs, MDNikhil Batra, MD
Meng Lu, MDJoseph Chen, MDDan Bettis, MD Leah Owen, MD, PhDJim Bell, MD
Ophthalmology training at the highest levels2012 ushered in an innovative education model at Moran—a “Resident Continuity Clinic” in which future
ophthalmologists start seeing patients on day one, under the supervision of a board certified ophthalmologist.
R E S I D E N T S A N D F E L L o W S
2013-2014m o r a n e y e c e n t e r
Krista Kinard, MD
Benjamin Thomas, MD
NEURo-oPHTHALMoLoGy
MORaNINTERNATIoNALFELLoWSHIP
Fantastic program, hospital, university, and location With 12 locations and four state-of-the-art ophthalmic surgery suites, over 40 ophthalmology specialists carry out more than 8,000 surgeries per year. The Moran Eye Center benefits from sufficient patient visits (120,000/year) to ensure a full spectrum of clinical and surgical experiences for both residents and fellows. The Moran residency and fellowship programs are crafted to mesh perfectly and to enhance the education of each individual specialist who we train.
the Department of ophthalmology and the moran eye center are key components of the 400-bed University Hospital and its satellite clinics. This includes more than 1,200 board-certified physicians staffing four University hospitals. Consistently ranked among US News & World Report’s “Best Hospitals,” we also “Best Hospitals,” we also “Best Hospitals,”provide training at the 131-bed Veterans Administration Medical Center and Primary Children’s Hospital.
Located at the base of the spectacular Wasatch Mountains, the University of Utah is the flagship institution of higher education in Utah. With world-class skiing, gorgeous desert country, and a population known for friendliness, Salt Lake continues to be ranked among the top cities in which to live—all factors contributing to making the postgraduate positions available at the John a. moran eye center a superb overall experience.
I N T E R N S A N D PAT H o L o G y F E L L o W Sm o r a n e y e c e n t e r
2013-2014InterInterInte ns & Ocularns & Ocular rns & Ocularns & Ocula Patholor Patholor gy Pathology Patholo Fellows 2013-2014gy Fellows 2013-2014gy
Eileen Hwang, MD, PhD Julia Byrd, MD Rene Choi, MD, PhD
Scott Cole, MD Joshua Ford, MD Justin Kohl, MD
I N T E R N S
o C U L A R P A T H o L o G y / R E S E A R C H
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Moran’s New Resident Continuity ClinicDay One: Meet Your Patient
Dr. Je� Pettey examines Fourth Street patient
Aabid Faruukhi, U of U medical student with a Fourth Street patient
Drs. Russell Swan, Zachary Joos, Krista Kinard, Jim Bell, Trent Richards, Derick Holt, Leah Owen, Dan Bettis, Brian Zaugg
2012 ushered in an innovative education model at Moran—a “Resident Continuity Clinic” in which future ophthal-mologists start seeing patients on day one, under the supervision of a board certified ophthalmologist.
Day One: Meet Your Patient Taking the helm as new residency program director and striving to continue to provide the most progressive, forward-thinking resident program, Dr. Jeff Pettey, Assistant Professor and As-sociate Program Director of Ophthalmology and Visual Sciences, evaluated current academic ophthalmology practices and models in the United States and worldwide, focusing on cutting-edge innovations in training and teaching. He found that residents may miss out on some important aspects of training that occur when a patient identifies a doctor as their primary eye care provider. As a result, he established a resident-staffed model “Continuity Clinic,” which provides opportunities for residents to follow patients during their training under the supervision of a board certified ophthalmologist. “The clinic provides a unique teaching environ-ment and an opportunity for residents to learn how to become the
provider for the patient in a well-supervised setting with graduated levels of responsibility, beginning day one,” says Dr. Pettey. “This is an opportunity for residents to really personalize their training.”
It begins as residents examine patients and propose a diagno-sis. Dr. Pettey also examines the same patients, teaching the residents throughout the process. Senior residents are able to diagnose and come up with a treatment plan, and Dr. Pettey then compares it with his own plan. For example, “We had a really complicated patient who had been to emergency two times then
Moran’s continually rising reputation and state-of-the-art graduate training program has resulted in a record-high increase in the number of resident applications received to date. “We just �nished interviewing 28 applicants out of 400 top-tier candidates and submitted our matches; it’s very exciting,” said Dr. Je� Pettey. �is year, the competition was more intense than ever.”
—Dr. Je� Pettey, January 2013
Dr. Tom Oberg, resident
came to the clinic with signs of a viral infection. He had a blood clot in his brain that would have killed him if not properly di-agnosed. A resident put the clues together—he knew exactly where the clot should be—and we sent him back to emergency for tests, literally saving his life. I’m frequently humbled that the residents’ level of knowledge is at times equal to or surpasses mine,” Dr. Pettey notes.
During clinics, residents see their own patient for the entire course of the patient’s treatment. Because the Continuity Clinic sees a low volume of patients—an average of six to ten per day—Dr. Pettey is able to take more time to teach, residents get more time with patients, and care is highly personalized. Some of the clinic’s patients are University Hospital in-patients who have complex medical problems and may come to Moran if they are medically stable. Others are seen at the Fourth Street Clinic as part of Moran’s local outreach efforts. Issues may range from loss of vision to diabetes to stroke, so residents get a range of experience. Interns see patients for one-half day each week, increasing patient time as they advance each year. Residents assist in surgery for the first two years and transition to primary surgeon their third year, when they apply to subspecialty fellowships—again, always under the supervision of a board certified ophthalmologist.
“I believe in finding the joy in every challenge, in every success,” says Dr. Pettey. “I get personally attached to the residents’ success—to get them to connect and see the vision—I’m still teaching, but the process is much more rewarding than a one-way teacher-student relationship. I learn from them every day.”
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A Clear Vision of ServiceMoran Resident Brian C. Stagg, MD, is Already Making a DifferenceIt’s no surprise that twenty-nine-year-old Moran resident Brian C. Stagg, MD, had plenty of choices when he was deciding on a residency program. In addition to having a decade of service projects, teaching, research, and publications to his credit, his resume includes a Bachelor of Science in Neuroscience and a minor in Portuguese with honors from Brigham Young University and a medical degree from the University of Utah. “I looked into several possibilities and found that the amount of experience residents get at Moran is really far above average—as is the faculty,” he says. “In most places, you don’t get an intern year with a lot of experience in ophthalmology, but with Moran’s Continuity Clinic we get a very special experience that includes building patient relationships.”
Dr. Stagg is as fascinated by the eye as he is motivated by build-ing relationships. Even before he entered the residency program, Stagg was deeply involved with Moran’s ongoing, monthly out-reach at Salt Lake’s Fourth Street Clinic—a free clinic that provides comprehensive healthcare to the city’s homeless population. He coordinated volunteers and managed the clinic, doing every-thing from scheduling appointments to making sure patients who needed further treatment actually made it to Moran and had a place to stay after surgery, if needed. When Moran doctors visited the clinic to help patients with issues from cataracts to diabetes, Stagg made sure that everything was set up and ready so they could go straight to work.
Now, he’s also a member of the team examining patients. “The chronically ill are a special challenge,” he notes. “I’m working on setting up special blocks of time for them because I think we can make a big difference and run the eye clinic more efficiently.” He also plans to help find ways to put better equipment in place and add another lane for examinations. “I like coming up with solutions, not staying with the status quo. Teaching, research, having a practice—I want to do it all.”
“I like coming up with solutions, not staying with the status quo. Teaching, research, having a practice—I want to do it all.”
—Brian C. Stagg, MD
Dr. Jeff Pettey, Hector Monjaras, Dr. Brian C. Stagg
Dr. Grant Morshedi, Kevin Kirk, U of U fourth-year medical student at Fourth Street Clinic
Brian C. Stagg, MD, received the 2013 Scholar Award from the Achievement Rewards for College Scientists Foundation Inc. (ARCS). The foundation’s mission is to “advance science and technology in the US by providing financial awards to academi-cally outstanding US citizens studying to complete degrees in science, engineering, and medical research.” Only US universi-ties whose departments are ranked in the top 100 in the country are eligible to receive ARCS Foundation Scholar Awards.
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Moran eye Center in your Community The Moran Eye Center provides comprehensive eye exams, fashion eyewear, and the latest contact lenses to meet all of your eye care needs. We have 13 locations along the Wasatch Front. Moran Community Clinics are typically located with a University of Utah Health Care Clinic, which provides a full range of world-class medical services.
2013m o r a n e y e c e n t e rC o M M U N I T y C L I N I C S
Moran Eye Center Doctors of Optometry
Robert Corry, OD
Timothy Gibbons, OD
Mark McKay, OD
Alan Morgan, OD
Harald Olafsson, OD
Clair Palmer, OD
Colleen Schubach, OD
Craig Smith, OD
Bryan Vincent, OD
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A self-described “spunky” ninety-�ve-and a-half-year-old, Elizabeth says she is “simply ecstatic” about her gi�, the matching donation, and the fact that David’s name will live on in Moran’s mission of providing hope, understanding, and treatment to all. In her words, “�e sight-saving work that Moran is doing all over the world and right here in Utah, in the Navajo Nation, just blows my mind!” Starting with their next mission to Nepal in October, Moran teams will carry and unfurl a huge banner with David’s face and name on it. �ey will �y the banner at each eye camp that they establish, eventually covering twenty-two countries on six continents.
Elizabeth’s Story Born in North Carolina in 1917, Elizabeth was just two years old when her mother passed away and she was sent to live with relatives in Salt Lake City. While it wasn’t the happiest childhood, she says she seems to have been “born with some kind of spunk inside—and a good dose of integrity and ability to see the true nature of people.” As a young “Tri Delt” at the University of Utah, she met and four years later married Raymond Irvin Johnson, an outstanding head-of-his-class “Pi Kap.” True to her ability to discern a person’s nature, she had fallen in love with a man who would become one of Utah’s most successful businessmen. �e youngest person ever to pass the CPA exam at age 22, Raymond was immediately snapped up by the FBI where he worked as a special agent, using his expertise to uncover a number of illegal �nancial schemes. A�er he resigned from the FBI, he started his own construction �rm—the largest in Marin County, California and nearby Lake Tahoe. A�er 20 years, he closed the construction �rm. “But he stayed active in the �nancial world, saving both Alpine Meadows and Park City Ski and Mountain Resort from bankruptcy,” says
Elizabeth. �roughout their marriage, Elizabeth took immense pleasure and pride in planting and nurturing her lush gardens, creating warm and welcoming homes, and traveling the world.
David’s Legacy She punctuates her conversation with smiles and twin-kling eyes, constantly gesturing with her delicate hands and eliciting laughs with pointed comments—and not much gets past her. But to this day, Elizabeth still has to stop and take a deep breath when she contemplates the sad and senseless loss of her grandson over 30 years ago. When he was just eight years old, David was hit and killed by a drunk driver while standing on the sidewalk on the street corner of Main Street in Salt Lake City. �at tragedy forever changed and a�ected Elizabeth; she has been a relentless crusader against drunk driving ever since. “I want people to know about what happened to David, and to remember it,” she says. “Please, do not drink and drive.”
Game-changer International Division Manager Michael Yei notes, “Elizabeth’s incredibly generous gi� is a true game-changer. �e David Kelby Johnson Hope Fund will allow us to expand our programs into new areas of desperate need— it will bring more sight-saving surgeries to so many more blind patients in some of the most neglected and underserved regions of the world, and it will give us a springboard for more long-term, sustainable programs.”
“I’ve always stood up for what I believe in,” Elizabeth is fond of saying. “And I really believe in Moran. �is gi� will help so many desperate young people to restore their sight and give them hope for a brighter future. David would be so delighted to know that he will forever be a part of that.”
When Elizabeth Hope Johnson of Salt Lake City dreams, she dreams big. One of her wishes has always
been to honor and share the memory of her late grandson,
David Kelby Johnson. In 2013 she made that wish come
true with an extraordinary, heart-felt donation to Moran’s
ongoing outreach programs—locally and around the world.
The center’s namesake, John A. Moran, matched her
donation of one million dollars, and Mrs. Johnson happily
christened it the “David Kelby Johnson Hope Fund.”
David Kelby Johnson
A Grandson’s Legacy and a Game-changer for Moran’s Outreach Program
HOPEFUND
David Kelby Johnson
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John A. Moran met Sam Skaggs in 1962 when Mr. Moran was a young investment banker just getting started. “Sam helped me complete my first financing transaction with the investment firm I joined after I’d been released from active duty in the navy,” Mr. Moran recalls fondly. “It meant a lot to me and boosted my confidence. I have never forgotten Sam’s belief in me and his longtime support. I consider him one of my dearest friends.”
Dr. Olson recalls a critical gift from the Skaggs family: “Two-and-a-half years after John Moran gave his lead gift toward the new 210,000-square-foot Moran Eye Center, Moran needed another major gift to begin construction. Sam Skaggs and The ALSAM Foundation stepped up with that second major gift, making it possible to construct our beautiful new eye center in 2006.”
The six-story L.S. and Aline W. Skaggs Research Pavilion at the Moran Eye Center unites more than 60 PhD vision researchers who were once scattered around the University of Utah Campus. It is also connected by bridges to our clinical facilities, symbolizing our desire to bring research discoveries to patient care as quickly as possible. These state-of-the-art research laboratories are helping to recruit top new scientists to Moran. Sam’s generosity is literally speeding up research that is bringing us closer to treatments and cures for vision loss.
Most recently, The ALSAM Foundation provided a generous donation for Moran researchers to work with Native American populations in Utah, a lifelong passion of Mr. Skaggs who felt a desire to help America’s underserved tribes. This donation is funding Moran molecular biologist and geneticist Dr. Margaret DeAngelis and her team as they carry out research
This year faculty, staff, and friends of the John A. Moran Eye Center lost a dear friend and generous
benefactor in the passing of Sam Skaggs. Dr. Randall J Olson, Chair of Ophthalmology and CEO of the
John A. Moran Eye Center, said this about Mr. Skaggs: “Sam Skaggs and John Moran have been spe-
cial friends throughout their lives. With Sam’s passing, we all feel we’ve lost a friend. Not only was he a
remarkable businessman, he was a dedicated husband and father. Sam and his dear wife Aline worked
hard and saved their money to create a better world through philanthropy. We see these same principles
mirrored in the lives of their children.”
The Expanding, Enduring Legacy of
“Let no one weep for me, or celebrate my funeral with mourning; for I still live, as I pass to and fro through the mouths of men.”—Quintus Ennius
Sam Skaggs
John A. Moran
L. Sam Skaggs
Moran Eye Center construction 2005
into retinal diseases among Native Americans. As Moran researchers carry out this program of research, we have been privileged to witness firsthand the legacy of giving that Sam Skaggs instilled in his children. Before his passing, Mr. Skaggs was delighted and proud to learn that his daughter Claudia was working alongside Dr. DeAngelis to ameliorate retinal disease in this population. Following in her father’s footsteps, Claudia is committed to quiet philanthropy and service and continues to donate her time to this program.
If Sam Skaggs could speak to us today, one wonders if he might echo the wish of Quintus Ennius and say: “Let no one weep for me, or celebrate my funeral with mourning; for I still live, as I pass to and fro through the mouths of men.”
The Philanthropy of Sam and Aline Skaggs
Making the world a better place for generations to come
Sam and Aline Skaggs have bestowed a legacy of giving personally and through The ALSAM Foundation and other entities they founded over the past 65 years. They have given hundreds of millions of dollars to education, health care, and research by way of scholarships, the establishment or funding of many university and research centers, and the nation’s largest single parochial elementary and secondary complex, located in Salt Lake City.
Six major universities have named either their pharmacy school or a building housing their pharmacy school after Sam and Aline due to their generous funding. Mr. Skaggs gave one of the largest gifts ever made to medical research for the creation of The Skaggs Center for Chemical Biology at The Scripps Research Institute.
Many universities and colleges have recognized the important effect Sam Skaggs has had on education. As early as 1970, he received a citation from the University of Utah that captures his spirit of giving: “To Mr. L.S. Skaggs, Jr., distinguished native son of the West, dynamic personality, and capable administrator in the distribution of pharmaceuticals and health care needs, leader in the intricate and competitive world of business, friend of education and research as the key to our successful future.”
The crown jewel representing Sam Skaggs’ commitment to education, health care, and research at the University of Utah is the new L.S. Skaggs Pharmacy Research Institute, which connects to the older pharmacy building constructed in the 1950s to honor Sam’s father. The joining of two buildings into one great school demonstrates the father/son commitment to education over 60 years. We’re proud to say that John Moran was a key donor to the L.S. Skaggs Pharmacy building.
Claudia Skaggs Luttrell and Dr. Margaret DeAngelis
John A. Moran Eye Center
L.S. Skaggs Pharmacy Research Institute
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Second Suns: “Required reading for anybody with an interest in humanitarian philanthropy…”—Outside Magazine
moRan’s DRs. GeoFFRey taBIn anD sanDuk RuIt
featured in New Book
Drs. Tabin and Ruit have dedicated their time and efforts to eliminating preventable blindness in the world by developing a revolutionary ten-minute surgery that costs about twenty dollars. Their system includes building self-sustaining hospitals in emerging nations and training local doctors who then train other local and international doctors in this surgical process. To date, Drs. Tabin and Ruit are directly or indirectly responsible for restoring sight to more than 1 million individuals in some of the world’s most isolated and impoverished nations, including those in the Himalayas and Sub-Saharan Africa.
Moran’s Role in a Sustainable Eye Care Model The Moran Eye Center sends ophthalmic surgeons on multiple international sight-restoring medical missions every year, including some of those featured in Second Suns.
Doctors from around the world are brought to the Moran Eye Center to observe and train with Moran ophthalmology specialists where they learn advanced techniques for restoring sight. They then go back to their home countries to perform these surgeries and to teach local physicians the same sight-restoring skills.
“Ninety percent of cataract blindness occurs in developing countries where such a curable affliction can actually lower the life expectancy by one-third,” said Tabin. “I’m proud to say that for the first time in history, we are witnessing the number of individuals with blinding eye diseases go down each year wherever our system is in place.”
Since its release June 18, 2013, Second Suns has been featured in hundreds of national and international broadcast, print, and electronic, media. Outside Magazine states that “Second Suns should be required reading for anybody with an interest in humanitarian philanthropy—or, for that matter, a desire to feel a little better about the world.”
The dedicated sight-restoring work of Moran faculty members Drs. Geoffrey Tabin and Sanduk Ruit, is chronicled in Second Suns, a recently released book by New York Times bestselling author David Oliver Relin. Dr. Tabin is Professor of Ophthalmology and Visual Sci-ences and Co-director of Moran’s International Division, specializing in corneal, cataract, and refractive care. Dr. Ruit is Adjunct Professor of Ophthalmology at the Moran Eye Center and Medical Director of the Tilganga Eye Centre in Kathmandu, Nepal. Relin’s captivating book tells the story of both doctors’ work to develop and improve eye-care delivery and to help cure preventable blindness in developing countries across the globe.
Drs. Sanduk Ruit, Randall J Olson, Geoffrey Tabin
contentSDonor Report 48
Appointments Honors and Awards 54
Industry Leadership and Service 56
Clinical Trials 62
technology commercialization and Intellectual Property/Patents 64
Grand rounds 66
Published Research 68
Research Grants and Contracts 72
national and International Presentations 79
APP
END
ICES
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gifts of $50,000 a n d a b o v e
Frank E. Delvie*
Willard L. Eccles Charitable Foundation
Alan J. Hirschfield
Ben B. and Iris M. Margolis Foundation
gifts of $25,000 a n d a b o v e
Avis Badami
Bamberger-Allen Health & Education Foundation
Bausch & Lomb
Wattis Dumke Foundation
IVEENA LLC
Elizabeth A. Johnson
Noel and Florence Rothman Family
gifts of $10,000 a n d a b o v e
Allergan, Inc.
ARCS Foundation Inc., Utah Chapter
Richard D. Bass
John I. and Toni F. Bloomberg
Brindle Foundation
Kathleen Digre, MD and Michael Varner, MD
Fred W. and Christine A. Fairclough
The Good Works Institute Inc.
Hoya Medical Singapore PTE LTD
Stephen A. and Elizabeth M. Huish
Stephen C. and Lynda M. Jacobsen
Robert A. and Joan Judelson
Gordon M. and Marcia* Olch
Rayner Intraocular Lenses LTD
Richard A. and Carmen Rogers
Snowbird Ski & Summer Resort
Denise R. Sobel
Strazza Family Trust
Hank and Sally Tauber
Jack C. Taylor
Susan O. Taylor
Utah Lions Foundation
James W. and Jeanne J. Welch
gifts of $5,000 a n d a b o v e
Alcon Laboratories Humanitarian Services
Balamurali K. Ambati, MD, PhD
Anew Optics
Bonnie Barry
Kurt Bestor
Dale A. and Janeel O. Burningham
William H. and Patricia W. Child
The Lawrence T. and Janet T. Dee Foundation
Errol P. and Sonja Chesley Eernisse
William K. and Fern H. England
Chase T. Hibbard and Emily L. Stonington
The Jarstad Family
Johnson Foundation
G. Frank and Pamela M. Joklik
Paul Joos, MD
James M. and Alison R. Luckman
Vicki B. Merchant
Herbert I. and Elsa B. Michael Foundation
Ralph P. and Marge L. Neilson
Kirk and Linda Nobis
Margaret D. Ordway
Powervision, Inc.
Rafati Foundation
DonorsThe following individuals and organizations contributed to the Moran Eye Center from January 1, 2012 through December 31, 2012
J o H N A . M o R A N E y E C E N T E R D o N o R R E P o R T F o R 2 0 1 2
2012
gifts of $1,000,000 a n d a b o v e
John A. and Carole Moran
gifts of $500,000 a n d a b o v e
The ALSAM Foundation
Edmund W. and Carol B. Dumke
gifts of $100,000 a n d a b o v e
John B. and Geraldine W.* Goddard
Val A. and Edith D. Green Foundation
Helen K. and Arthur E. Johnson Foundation
Sylvia Prahl-Brodbeck
Hazel M. Robertson
Khosrow B. and Ghazaleh Semnani
Lincoln Shurtz and Lisa Harrison
West Jordan Lions Club
Linda Lewis Wolcott and J. M. Steele
gifts of $1,000 a n d a b o v e
Aaren Scientific, Inc.
George M. Ahn
G. W. and Ida Lee Anderson
N.L. and David R. Anderson, MD
Dan Bass
Raymond E. and Janette H. Beckham
Joseph C. and Gainor L. Bennett
William F. and Victoria F. Bennion
Bennion Jewelers
Ann and Paul Bernstein, MD
BMW of Murray
Bob Bonar
Rodney H. and Carolyn H. (Mitzi) Brady
Eveline Bruenger
Timothy L. Byers, MD, PhD
Laura D. Byrne
Robert A. and Ann Janette L. Carlson
Robert S. Carter Foundation, Inc.
Irene G. Casper
Robert Cionni, MD
Whitney O. and Frances R. Cluff
Kenneth D. Collins
Julie Crandall and Alan S. Crandall, MD
F. Anthony and Joyce G. Crandall
Robert W. and Carol N. Culver
CycleSmith
de Conde’s
Tim and Candace Dee
Barbara S.* and George L. Denton, Jr.
Cameron Brady Diehl
Larry A. Donoso, MD, PhD
Porcupine Pub & Grill
Linda Rankin, PhD
Richard F.* and Jan Rasmussen
Raymond James Charitable Endowment Fund
Ron and Carolyn Reaveley
The Regence Group
Edward N. and Carol S. Robinson
Rockwell Collins
Michael and Bonnie Rothman
Clough and Kay Shelton
Howard S. Spurrier, DDS
Tom and Kristin Stockham
Strong Audi
Blake E. and Cindy Ann Strong
Brad D. Strong
O. C. Tanner Company
Tueng T. Shen, MD and Jan H. Thijssen
Yvette S. Ungricht
James H. and Rolande K. Vaughn
M. Walker and Sue R. Wallace
WanSutter Insurance
Anna M. and Jeffrey R. Weis, MD
Weis Eye Center, PA
Luree and Robert C. Welch, MD
Thacher W. White and Doris Blazek-White
James R. and Linda R. Wilson
Terry L. Wright
Louise and Norm A. Zabriskie, MD
Robert C. and Patience Ziebarth
gifts of $100 a n d a b o v e
Abel Automatics, Inc.
G. Howard Abplanalp
Ann Acaya and Greg Balch
Curtis E. Ackerlind, Jr.
Joel Adams Photography
Jean W. Adamson
Jess and Olivia Agraz
E. R. (Zeke) and Katherine W. Dumke
Jane Durcan, MD and John Hoffmann, MD
Eye System Inc.
Michael A. and Muffy M. Ferro
Carol W. and John H. Firmage III
Joan B. and John H. Firmage II
Cecelia H. Foxley, PhD
Friberg Fine Art, Inc.
Angela and Michael T. Furlong, MD
Nicholas and Courtney Gibbs
Jason A. Goldsmith, MD
Adrienne Graves
Leah Hatziathanasiou and family
C. Charles and Elise Hetzel
Carolyn S. and Robert O. Hoffman, MD
Ann Hollowell
Howard Rodney Horinbein
Alan E. and Drue B. Huish
Frank J. and Sarah G. Johnson
Brad, Tracey, Sam, Jonah, and Zev Katz
Ace Kvale
Mihail S. Lari and Scott E. Murray
James C. Lewis, JD and Carol L. Jent
Marmot Mountain LLC
Beth A. and Edward M. McGill, MD
Ambrose P. McLaughlin, III, MD
Peter R. and Kathy R. Metcalf
Valerie A. and Mark D. Mifflin, MD
Corey A. and Nancy J. Miller
Ruth A. Morey
G. Mitchell* and June M. Morris
Michael V. and Paula F. Morris
Mimi B. Mortensen
John J. Moy
George G. and Pauline Mulligan
Marilyn Olson
Ruth L. Olson and Randall J Olson, MD
Outdoor Research
J o H N A . M o R A N E y E C E N T E R D o N o R R E P o R T F o R 2 0 1 2
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Steven and Susan Dewey
T. Jerald and Carol D. Diana
Chantryce Elana Diehl
Raymon E. Diehl
The Dirty Dash
Vera Caren Dixon
The Dodo Restaurant
Draper Lions Club
Gaye N. and R. Michael Duffin, MD
George H. and Joan D. Earl
Steven George and Ingunn Hoff Earl
Joshua D. Echols
M. David Eckersley and Anne Milne
John S. and Evelyn B. Edwards
Sarah and Bob Ehrlich
Rolf Engen
Falcon’s Ledge
James Farmer
Fat Cats
Richard A. and Carol M. Fay
Michael S. and Eugene Feldman
Spencer P. and Barbara S. Felt
Fish Tech Outfitters
Carole E. and Bruce R. Fishburn, MD
Keith A. and Cindy Hadden Fleming
Flowrider
Foothill Oriental Rugs
Frankie Ford
Stanley and Janice T. Foutz
Bonnie O. and Joseph B. Fowler, Jr.
Arthur E. and Victoria E. Franks
Peter Q. Freed
Heidi L. and Roger C. Furlong, MD
Jay and Lynda Gamble
David Ganansky and Cindy Nordling
David P. and Sheila S. Gardner
Paul E. Garland, MD
Gastronomy, Inc.
Deanna R. Gerber
Hans G. and Martha S. Ahrens
Alcohol Servers Training of Utah LLC
Richard A. Aldous, MD
Raymond H. and Ila Jane Aldrich
Ray W. and Bonnie Lou Alvord
Anil Amoogum
Gaby Anderson
Milton M. and Dianne K. Anderson
Catherine and Barry J. Angstman
Joey Archer
Mark and Christine Archibald
Aristo’s
John W. and Diane V. Armour
AsArt
Alan C. and Karen Ashton
Pamela J. Atkinson
Leah A. Baker
Jean S. Barker
Robert R. and Laurel Barrett
Surya Bastakoti and Carmen L. Fournier
Lloyd and Nancy Beacom
Jon C. and Carol L. Beck
Beehive Bail Bonds
Patricia Ann Berg
Brian Besch
Carl M. Biehn
Black Diamond Equipment, Ltd.
Emmy S. Blechmann
Elmen D. and Monika Bloedel
Elizabeth B. and H. Allen Bloomer, MD
Blum, Inc.
Steven J. Borst
Dave D. and Cate H. Boulden
Betsy T. Bradley
Stephen K. Bradley, MD
Carolyn O. Braza
Hugh and Constance Brennan
J. Steven and Susan J. Brown
Dolores Z. Buchanan
Shirley E. and Billie N. Burke
John K. Bushnell
William L. and Sheral L. Calvin
Robin C. Campbell and Marion Rogers Riley
Canyons Resort
Robert S. and Kimberly Ann Carson
Rameshwor Chapagain
Michelle and Craig J. Chaya, MD
Todd Chikaraishi, DDS
George A. and Pauline O. Childs
Qing Chong
Don V. and Anne E. Christensen
Mary T. and Andrew B. Christensen, PhD
Thayer S. and Sue D. Christensen
The Church of Jesus Christ of Latter-day Saints Foundation
Glenn D. and Kara E. Clapp, PhD
Willa Dean Cocorinis
Richard and Susan Coe
Cole Sports
Joseph V. & Nancy C. Cook
Robert D. and Cheryl D. Cook
Drury W. Cooper, III
Michael* and Diane Cooper
Ed and Deborah A. Cooper
William and Barbara B. Cowan
Vicki Cram
Lisa Z. and David A. Crandall, MD
Rufus L. Crawford
Yue and Donnell J. Creel, PhD
Paul B. Crookston
Alan S. and Joan E. Cruickshank
Craig W. Dayhuff
Deerfield Ranch Winery
Edward R. and Terri Dejulis
Denver Eye Surgeons
Gwila C. Despain
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Stephen L. and Leslie Goddard
Lawrence K. and Suzanne Goldsmith
Roxanne Googin
Shari Gowers
Robert M. and Joyce S.* Graham
Grant Farms
Neil J. and Stephanie D. Gray
Donald R. and Susan Greenberg
The Group Real Estate, LLC
Thomas L. and Victoria E.* Guinney
Doug and Kristy Gunnell
David G. and Donna Ann Hall
John R. and Andrea M. Hampshire
Barry K. Hanover and Allison R. Brunvand
Gerald and Betty Jo Hanson
Sylvia and Roger P. Harrie, MD
Joy T. Hashimoto
Barbara Ann Hathaway
Jim and Jennifer Hathorne
Rick F. and Jane R. Hays
William G. Hayward, Jr.
Jack Hegardt Masonry
John B. and Jean M. Henkels
Gary J. and Elvia I. Hennings
Ruth A. Hensel
Margaret D. and Hillard D. Hicks
Hidden Valley Country Club
David C. and Eileen Grevey Hillson
Himalayan Kitchen Restaurant
Ross and Kathy S. Hinman, DVM
Einar and Madora I. Hoff
H. Earl and Barbara C. Hoover
Edward L. Hughes and Roberta L. Anner-Hughes
Gilbert H. and Thelma P. Iker
James F. Ingold
Intermountain Harley Davidson
Edward M. and Nita Jenkins*
Martha Lewis Jennings
Jerry J. and Roslyn Jensen
Norman S. and Gail R. Jensen
Lars and Kendeyl D. Johansen
Johnie’s
Thomas P. and Wendy A. Johnson
Patty S. and Randolph L. Johnston, MD
Ryan C. and Jaime Lynn Jones
Leon L. and Judith Anne Jones
Zachary Joos, MD
Carol A. Jost
Wally Joyner
Michael J. and Dianne Jean Kane
Alan and Pam Kantrowitz
Charles and Laurel D. Kay
Kearns Lions Club
KEEN
Dennis Keller
Jean L. Kendall
Carl R. and Gillean M. Kjeldsberg
William M. and Julia J. Kleinschmidt, PhD
Rodney James Korst and Lynn Price, MD
Peter and Geraldine S. Kypreos
Polly I. Lambson
Larry G. and Dixie D. Lehman
Larry G. and Claire O. Leonard
Ralph M. and Susan M. Lewis
Links to Clinical Research LLC
Laura P. and Robert P. Liss, MD
Richard M. and Susan N. Lockwood
Los Miradores Unit Owners Association
James L. and Carol C. Macfarlane
Mercina and Nick Mamalis, MD
Mammco, LLC
Tad and Mary Mancini
Brent V. and Chris C. Manning
Michael and Andrea Manship
Franklin Marold
Julie Marple
Steven and Karen Marsden
George and Connie Marshall
William A. Marshall
Charles and Florence I. Masters
Willard Z. and Rona Lee Maughan
Les E. and Therese M. Mayes
Mayfield Lions Club
David and Laura McArthur
Sandra and Duncan K. McDonald, MD
Molly L. McFadden
Daniel J. McInerney
Scott E. McIntosh
Ms. Jeanne L. McJoynt
Philip M. and Susan L. McLaughlin
John and Emily McVey
Don and Mary Mealing
Marvin and Renee Melville
Lloyd R. and Marjorie R. Merrill
Larry H. Miller Sports & Entertainment Group
Patricia G. Millington
Nathan Miller
Aditya V. Mishra, MD
Montebello Truck Terminals
Montgomery Fur Co.
Amedee D. and Cammie Moran
John A. Moran Eye Center Optical Shop
Judith S. Moreton
Anthony W. and Mary Ann Morgan
John and Cherie Morris Family Foundation
Anna C. and Grant Morshedi, MD
Mountain Film in Telluride
Mountain Trails Foundation
Mountain View Animal Hospital
Gene Muir
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Spencer 2010 Vision PC
Heather and Terrence Scott Spencer, MD
Squatter’s Pub Brewery
Marland L. and Rachel Stanley
Robert and Rosemary Starr
Shirley N. Stevenson
Thomas G.* and Martha G. Stockham
John R. and Helen B. Stone
William E. and Dena Stratton
Preston and M. Catherine Strazza
Charles and Kathleen Feid Sturgis
Raju Subedi
Carlton T. Sumison
Sundance Institute
Super Sonic Car Wash
Edward Harris Sweet
Geoffrey Tabin, MD
Lary J. and Judy W. Talbot
William Tanner & Susan Heath
Carolyn W. and Kim Y. Taylor, MD
Mark Taylor
Robert C. and Jacque Taylor
R. Burke Teichert
Thanksgiving Point
David B. Theobald
Mary E. Thompson
Craig Tinkham
Lilian S. Tinsley
Kris Tribe and Scott S. Hale
Jim and Candy Turnbull
Kirk A. Umphrey, CPA
Stephen C. and Kathy Ure
Paul and Kristi Ann Urry
Utah Mountain Adventures
V Chocolates
Maynard H. and Carol B. Victor
Vinto Restaurant
Albert T. Vitale, MD and Patricia A. Vitale, MD
Ron and Kris Murri
Bobby Nassir
Native Eye Wear
William H. and Christine M. Nelson
Newpark Resort and Hotel
Hanh T. Ngo
Roland C. Nickerson
Samdup Norgyal and Thupten Wangmo
Jennifer Norris, MD
Michael A. Norseth
Clay W. and Dianne R. Northrop
David E. Oberly and Karen Ehresman
Charles W. and Joan Odd
James and Sandra O’Hearn
The Olive Garden
Osprey Packs
Outdoor Utah
Eugene and Jean Overfelt
Paisley Pomegranate
Richard D. Paisner and Christie Weiner
Joseph J. and Dorothy Ann Moyle Palmer
Park City Lions Club
Karen and Matthew R. Parsons, MD
Patagonia
Gregory G. Pavich
Chase N. and Grethe B. Peterson
Elaine Peterson
Gary Peterson
Peter W. and Anne P. Peterson
Raymond R. and Judith C. Peterson
PETZL America
Piaget Designs
Marlynn Pike
Paul Z. and Lisa Dang Pilzer
Ralph W. and Maurine* Pixton
Blanche B. Prisbrey
The Pub Group
Susan J. Quaal, PhD
James W. and Brunhilda Rail
Elizabeth D. and V. Ramama Rao
Mervin J. and Verna B. Rasmussen
L. Richard and Jean C. Raybould
Debra S. and J. Scott Raymond, MD
Colleen M. Reardon
Ralph E. and Rita G. Reese
Donald G. Reid
Research to Prevent Blindness
Saeed Rezai and Christine M. Turner-Rezai
Gladys Richardson
Alvin and Helene Richer
Phil and Glenda Riesen
Manda and Robert E. Robinson, JD
Ron Rubin
Susan L. Ruebush
Melodie Rydalch
Saari Revocable Trust
John M. and Melanie A. Sacco
David E. and Lois P. Salisbury
Salt Lake Country Club
Salt Lake County Government Center
Salt Lake Marriott Downtown
Paul F. and Janice W. Sargent
Tasha Savage
Peter and Jutta Scholla
John F. Schroll
Susan B. Schulman
Michael R. Scott and Loretta G. Falvo-Scott
Sego Art and Frame
Jerry Seiner Chevrolet Employees Fund
Roger Shane
Pamela B. Sheeler
William Simkins
Albert H. Small
Quentin R. Smelzer, Jr.
Clark T. Smith
Otto F. Smith, MD
Mark E. and Vicki L. Southwick
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William L. and Nancy Y. Wagner
D. Jesse and Ann T. Wagstaff
Gerald Wallace and Ruth Y. Cooke
W. Jeffrey and Mona Walters
Jana C. and Curtis R. Ward, JD
Matthew and Lynn W. Ward
Jeffrey S. Ware
Judith E.A. Warner, MD
Marta Sutton Weeks-Wulf
George P. and Adele W. Weiler
Wells Fargo
Marilyn F. Westegaard
Bart L. and Marlene G. Wheelwright
Pauline Wiessner, PhD
Don M.* and Joleen Willey
John W. Williams
Gordon R.* and Georgia A. Wilson
Jennifer Wilson and Trell Rohovit
Ted L. Wilson and Holly J. Mullen
David B. and Jeralynn T. Winder
Pamela and Robert W. Wing, MD
Wisan, Smith, Racker & Prescott
Bruce R. and Jean P. Wisan
Richard and Nancy S. Wolthius
Michael H. Yei and Jill A. Miller
Zy Restaurant
I N H O N O R O F
Those in whose honor gifts were made to the Moran Eye Center from January 1, 2012 through December 31, 2012
Captain Daniel M. Anderson, MD
Paul S. Bernstein, MD, PhD
Kim Corbin-Lewis and David R. Lewis
Julie and Alan Crandall, MD
Laverne and David Diehl
Jason Goldsmith, MD
Susan W. Hodgins
Alan E. Huish
Collin G. Jensen and Heidi J. Hunsaker
Brandon and Rebecca Jensen
Bradley Katz, MD, PhD
Bonnie and Ernie Messerly
John A. and Carole Moran
Majid Moshirfar, MD
Terry and Tiffany Parkin
Matthew R. Parsons, MD
Matthew Porter
Tami Porter
Thomas Starkovich
Michael P. Teske, MD
Albert Vitale, MD
John Waldrip
I N M E M o R y o F
Those in whose memory gifts were made to the Moran Eye Center from January 1, 2012 through December 31, 2012
Louis B. Baker
Elizabeth R. Beier
Maxine Bernhisel
Charles W. Bezyack
Eugene (Jim) Smith Bezzant
Robert Buchmiller
Thomas Callahan
Dan Changar
Dan Collings
Eloise and Kirkham V. Crabb
Helen Bell Crawford
Robert V. Despain
Clifford Benjamin Digre
Robert Duke
Donald “Don” Eyre
Edith A. Fallentine
Susan Fallentine Flatberg
Jack Forgie
Mildred Gawlicki
Ted Hallstrom
Mark Hanna
Martha Ann Dumke Healy
Margaret Hutchings
Jennie Janzen
Clara Jaques Richins Jensen
Lois E. Bleak Johnson
Tim Lynch
Thomas J. McJoynt
Kevin Craig McKenna
Fern Whicker Mortensen
Steven Nichols
Elaine Nielson
Donna Olson
Don Percival
Neuman C. Petty
Anna K. Picco and Patricia Politano
Robert A. Pirtle
Maurine Pixton
Ramona Rochford
Lynn Seely
Edward G. Shearer
Robert C. Sloan
James H. Swonson
Isabel Thomas
Effie Torrey
Elton Varner
Leslie Wansgaard and Pearl Kirk
Don Willey
William Meeks Wirthlin
*Deceased
The Moran Eye Center is very grateful for the contributions made to support our mission and goals. We have made every effort to ensure that this 2012 Donor Report is as accurate as possible. Should you find an error or wish to change your listing, please feel free to contact us at 801-585-9700.
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Appointments, Honors, and Awards
AppointmentsBalamurali K Ambati, MD, Official Utah Utes Team OphthalmologistPhD, MBA
Mary Elizabeth Hartnett, MD International Association for Research in Vision and Ophthalmology (ARVO) Program Committee for Retinal Cell Biology
Chair Elect, ARVO Ethics and Regulations in Human Research Committee Study Section for Diseases and Pathology of the Visual System
Women in Ophthalmology Audit Committee
National Research Policy Committee, American Diabetes Association
Credentials Committee, Macula Society
University of Utah Committee for Academic Promotions, Retention, and Tenure
Academic Senate Teleophthalmology Board
Wayne Imbrescia, MPH, MHSA President of University Administrators of Ophthalmology
Nick Mamalis, MD Governing Board, American Society of Cataract and Refractive Surgery
Randall J olson, MD President of the Association of University Professors of Ophthalmology April 1, 2012 – March 31, 2013; continuing to serve in the capacity of Past President until March 2014
Liliana Werner, MD, PhD Board member, Institutional Review Board, University of Utah
Honors and AwardsWolfgang B Baehr, PhD Association for Research in Vision and Ophthalmology’s highest research honor,
a $100,000 prize from the ALCON Research Institute for research that is likely to “expand the frontiers of vision sciences throughout the world”
Kathleen B Digre, MD Rosenblatt Prize for Excellence, the University of Utah’s highest faculty honor
Martha Hughes Cannon Award for contributions to women’s health in the state of Utah, Utah Department of Health
R Michael Duffin, MD Recognition for Humanitarian Service from FUDEM, a woman’s humanitarian service organization dedicated to providing eye care to the needy, in El Salvador at their 20th Anniversary Celebration, San Salvador
yingbin Fu, PhD National Eye Institute Travel Award, XVth International Retinal Degeneration Symposium, Bad Gögging, Bavaria, Germany
James Gilman, CRA, FoPS Honorable Mention for “Ravenous Retinopathy” and Second Place for an “Iris Tumor” at the Ophthalmic Photographers’ Society (OPS) Scientific Exhibit at the American Academy of Ophthalmology Annual meeting
Outstanding Contribution Award for five years of teaching from the Joint Commission on Allied Health Personnel in Ophthalmology
Gregory S Hageman, PhD Lighthouse International Madame Georgette Pisart Vision Award for the “most extraordinary advance in the field with work of an enduring nature that has inspired others”
Prix de la Recherche, Macula of Paris
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2012-2013Senior Scientific Investigator Award, Research to Prevent Blindness
Harold Gifford Jr, MD, Lecture, Stanley M Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, Nebraska
Congressional Briefing Featured Speaker, AEVR Sponsored International Age-related Macular Degeneration Week 2012, 20 September, Washington DCAge-related Macular Degeneration Week 2012, 20 September, Washington DCAge-related Macular Degeneration Week
Roger P Harrie, MD Annual Service Award from the Salt Lake Valley Youth Detention Center for a glasses project in which he checks the eyes of youth in detention and donates glasses to those who need them
Mary Elizabeth Hartnett, MD Representative nominated by Retina Society for Practicing Ophthalmologist Curriculum
Robert o Hoffman, MD Lewis Peterson Award at Primary Children’s Medical Center, Principle Investigator-eROP, Utah Study Center
Bryan W Jones, PhD First Place, International Science and Engineering Visualization Challenge sponsored by the journal Science and the National Science Foundation
Julia Kleinschmidt, PhD, LCSW Awarded Emeritus Professorship, the University of Utah, 2012
Nick Mamalis, MD Best Poster Award – ASCRS/ESCRS, 2012: Survey on Foldable IOLs Requiring Explanation or Secondary Intervention: 2011 Update. American Academy of Ophthalmology annual meeting, Chicago , Il
Robert E Marc, PhD University of Utah Distinguished Professorship
Mark D Mifflin, MD Residents’ Outstanding Faculty Member Award, 2012
Richard A Normann, PhD Presented with a Festchrift, “a volume of learned articles or essays by colleagues and admirers, serving as a tribute or memorial especially to a scholar,” honoring his 70th birthday, February 8, 2013
Randall J olson, MD Binkhorst Medal of Honor for “an individual as making significant contributions to the science and practice of ophthalmology and establishes that person among the world’s most prominent ophthalmologists,” American Society of Cataract and Refractive Surgery
Binkhorst Award for American Society of Cataract and Refractive Surgery, 2012
Monica Vetter, PhD Innovative Ophthalmic Research Award for Research to Prevent Blindness;Chair, 1 R13 EY020680 Visual System Development Gordon Research Conference, 2010 Visual System Development
Liliana Werner, MD, PhD Best-Paper-of-Session Award, Session 3-N IL Intraocular Surgery Complications: “Pathological Assessment of Complications with Asymmetric or Sulcus Fixation of Square-edged Hydrophobic Acrylic IOLs,” the Annual Meeting of the American Society of Cataract and Refractive Surgery, Chicago, Illinois
First Prize, EDUCATIONAL category for The Art of the Pre-chopping: Analyses from the Miyake-Apple Perspective, at the video festival of the XII International Congress of Cataract and Refractive Surgery Video Festival, São Paulo, Brazil
Afonso Fatorelli Medal and Lecture, XII International Congress of Cataract and Refractive Surgery, São Paulo, Brazil
The Mamalis/Werner Lab received a donation from Alcon Laboratories in the value of $50,000 dollars to support analyses of light scattering and light transmission of explanted intraocular lenses. Alcon also provided two pieces of equipment in the value of $30,000, which are essential for these analyses: an anterior segment analyzer (EAS-1000 Scheimpflug camera, Nidek) and a UV-Vis spectrophotometer (Perkin-Elmer Inc)
Paul Zimmerman, MD The family of the late Dr. Zimmerman, former ophthalmologist and educator at the Moran Eye Center, along with the Utah Lions Eye Bank and many other donors, made possible the purchase of a state-of-the-art eye surgery simulator (EYESi) to enhance education and training programs. Dr. Zimmerman, the Utah Lions Eye Bank, and other donors who helped purchase the simulator were honored at an event held at Moran Eye Center, 18 September, 2012
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Balamurali K Ambati, MD, PhD, MBA2008-Present Section Editor, American Academy of Ophthalmology, Basic & Clinical Science course in ophthalmology
Ad Hoc Member, National Eye Institute, Special Emphasis Panel
Alessandra Angelucci, MD, PhD2008-Present Review Editor, Frontiers in Neuroanatomy
2007-Present Member, Editorial Board for Visual Neuroscience
Review Editor, Frontiers in Systems Neuroscience
2007-Present Member, American Physiological Society, USA
2002-Present Committee Member, Departmental Distinguished Speaker Seminar Series, Department of Ophthalmology, University of Utah
1997-Present Member, British Neuroscience Association, UK
1994-Present Member, Society for Neuroscience, USA
1990-Present Member, Italian Medical Doctors Association, Italy
Wolfgang B Baehr, PhD 2012 Organizer, the 14th Annual Vision Research Conference, Board of Vision Research; a two-day meeting on Retinal Ciliopathies: From Genes to Mechanisms and Treatment, preceded ARVO, Ft. Lauderdale
Organizer, the five-day XX Biennial Meeting of the International Society for Eye Research, Retinal Neuroscience, Berlin, Germany
Editor, Vision Research, volume 53, (2012). Special Edition of the 14th Biannual Vision Research Conference on “Retina Ciliopathies: From Genes to Mechanisms and Treatment”
2004-Present Senior Editor, Vision Research, Elsevier Science, San Diego, CA
Paul S Bernstein, MD, PhD 2012-Present Member, Board of Trustees, Association for Research in Vision and Ophthalmology
2011-Present Organizer, the 17th International Symposium on Carotenoids, Park City, Utah
2008-Present Mary Boesche Endowed Professor of Ophthalmology and Visual Sciences
2008-2011 Committee Member, Biochemistry Program, Association for Research in Vision and ophthalmology
2006-Present Elected Member, America’s Best Doctors
2005-Present Medical Advisor, Journal of Ophthalmic Photography, University of Utah World class U award
Member, Scientific Advisory Board, International Symposium on Ophthalmic Pharmacology and Therapeutics
Margaret DeAngelis, PhD 2012-Present Member, Executive Committee, International Consortium for Refractive Error and Myopia, sponsored by NEI/NIH
Member, Editorial Board, International Scholarly Research Network Genetics
Member, International Consortium for Refractive Error and Myopia
Member, Age-related Macular Degeneration Gene Consortium
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2012Industry Leadership and ServiceThis is a partial list of Moran Industry Leadership and Service for 2012
2012 Member, National Institute of Health ZRG1 F05-R Fellowship: Cell Biology, Development, and Bioengineering Study Section
Member, Macular Degeneration Foundation, Australia Research Grants Program, Peer Review Panel
Session Co-chair, “Nuclear Receptors and their Role in the Retina and in AMD,” Biennial Meeting of the International Society for Eye Research, Berlin, Germany
Chairperson, Rapid Fire Presentations: 9th Alumni & Research Day, Centre for Vision and Vascular Science and Royal Hospitals, Queens University, Belfast, Ireland
Judge, Post-doctoral Fellows Poster Sessions: 9th Alumni & Research Day, Centre for Vision and Vascular Science and Royal Hospitals, Queens University, Belfast, Ireland
2011-Present Member, Senior Executive Committee/Steering Committee, Age-related Macular Degeneration Gene Consortium, sponsored by the NEI/NIH
2010-Present Member, National Institutes of Health, Research Peer Review Panel, Edinburgh, Scotland, United Kingdom
Member, Australia Macular Degeneration Foundation, Research Peer Review Panel
2008-Present Member, Guide Dogs for the Blind, Research Peer Review Panel, United Kingdom
Kathleen B Digre, MD 2010-Present Member, Achievement Rewards for College Scientists
2007-Present Visiting Professor, American Academy of Ophthalmology, Neuro-Ophthalmology/Orbit, Differential Diagnosis of Headache and Eye Pain
2004-Present Chairman, Board of Directors, North American Neuro-Ophthalmologic Society
Chair, American Headache Society Publications Committee
2003-Present Member, American Neurological Association Membership Committee
Member, International Genetic Epidemiology Society
2002-Present Member, American Headache Society Review Board
2001-Present Representative, American Neurological Association, to One-Voice (aka American Brain Coalition)
Fellow, American Heart Association Stroke Council
1999-Present Member, American Headache Society Grant and Awards Committee
Member, Association for Research in Vision and Ophthalmology
1998-Present Board of Directors, Member, North American Neuro-Ophthalmology Society
1995-Present Member, Editorial Board, Journal of Neuro-Ophthalmology
R Michael Duffin, MD 2012 Member of the Vision Advisory Committee of the Humanitarian Department of The Church of Jesus Christ of Latter-day Saints, with responsibilities to assist in developing humanitarian vision care projects for the needy in Latin America
2008-Present Member, Interview Sub-committee of the Admissions Committee of the University of Utah School of medicine
Sabine Fuhrmann, PhD 2011-Present Academic Senate
2012 Member, Molecular Biology Graduate Program Admission Committee
2012 Internal Reviewer, Graduate Council Review for the Department of Pharmacology and toxicology toxicology t
2012 Member, Funding Incentive Seed Grant Program
2004-Present Member, Editorial Board, Developmental Dynamics
Member, Society for Neuroscience, Association for Research and Vision in Ophthalmology, Society for Developmental Biology, Research to Prevent Blindness
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Gregory S Hageman, PhD 2012 Scientific Founder, Voyant Biotherapeutics LLC, Salt Lake City, UT
Member, National Eye Institute, Age-related Eye Disease Study 2 Advisory Group
Member, NIH ZEY1 VSN Study Section
Member, National Eye Institute Age-related Macular Degeneration Gene Consortium
2012-Present Member, Sequenom, Inc., Ophthalmology Clinical Advisory Board
2011-Present Advisor, Gerson Lehrman Group
Member, Foundation Fighting Blindness Scientific Advisory Board
2010-Present Member, Macular Degeneration Foundation Australia Scientific Committee
Member, Advisory Board, ViroPharma Incorporated
Advisor, Apeliotus Technologies Inc.
Member, American Society for Cell Biology
Member, American Society for Matrix Biology
Member, Association for Research in Vision and Ophthalmology
Member, Central States Microscopy & Microanalysis Society
Member, Electron Microscopy Society of America
Member, International Complement Society
Member, International Society for Eye Research
Member, International Society for Matrix Biology
Member, International Society for Ocular Cell Biology
Member, Macula Society
Member, Phi Beta Kappa
Member, Schepens International Society
Member, Sigma Xi Scientific Research Society
Member, Society for Neuroscience
2009-Present Member, AMD Alliance International Board of Directors
Member, Executive Committee, Arnold and Mabel Beckman Initiative for Macular Research
Member, Edward N & Della L Thome Memorial Foundation Scientific Review Committee
Member, Alcon Research Institute
Advisor, Allergan Pharmaceuticals, Irvine, California
Mary Elizabeth Hartnett, MD 2012 Committee Member Elect, ARVO Program for Retinal Cell Biology
Chair Elect, ARVO Ethics Committee
Member, National Eye Institute Study Section for Diseases and Pathology of the Visual System
Member Elect, Board of Directors, Women in Ophthalmology
Member, National Research Policy Committee, the American Diabetes Association
Member, Credentials Committee, the Macula Society
Member, Committee for Academic Promotions, Retention, and Tenure; Academic Senate Teleophthalmology Board, University of Utah
Organizer and Host, International Association for Pediatric Retinal Surgeons Meeting, Park City, Utah
2012-Present Editor, American Academy of Pediatric Ophthalmology and Strabismus
2011-Present Editor, Molecular Vision Scientific Review
2009-Present Member, Honorary Editorial Board, Patient Related Outcome Measures (Dove Press)
2009-Present Member, Honorary Editorial Board, Eye and Brain
Member, Editorial Board, Clinical Ophthalmology
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Bryan W Jones, PhD 2002-Present Editor/Webmaster, Webvision http://webvision.med.utah.edu
1992-Present Member, American Association for the Advancement of Science
1999-Present Member, Association for Research in Vision and Ophthalmology
2004-Present Member, Medical School Admissions Committee
Bradley J Katz, MD, PhD 2011-Present Member, Self-assessment Committee, Item Review Subcommittee, American Academy of Ophthalmology
Primary Investigator, Technology Commercialization Project Grant, “Development of Thin Films to Treat Photophobia and Migraine,” University of Utah Technology Commercialization Office
2009-Present Primary Site Investigator, Phase I Open Label, Dose Escalating Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Patients with Optic Nerve Atrophy (Stratum I) and Acute Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) (Stratum II), QUARK Pharmaceuticals, Fremont, California
Member, Committee on Aging, American Academy of Ophthalmology
David Krizaj, PhD 2012 Moderator, Association for Research in Vision and Ophthalmology, Membrane Physiology,
and Signal Transduction Poster Session
Member, Special Interest Group, Association for Research in Vision and Ophthalmology
Co-organizer and Moderator, RGC Death in Optic Neuropathies and Retinal Ischemia
Session Co-moderator, “TRP Channels in Eye Research,” International Society for Eye Research Conference, Berlin
2012-Present Member, Editorial Board, Center for Translational Medicine, University of Utah
2011-Present Member, Editorial Board, International Journal of Physiology, Pathophysiology and Pharmacology
2010-Present Member, Editorial Board, Society for Neuroscience Intermountain Chapter, Open Access Animal Physiology
2009-Present Member, American Physiological Society
Member, Scientific Inquires in Qualia Interdisciplinary Faculty Research Interest Group under auspices of Tanner Humanities Center
2007-Present Member, American Association for the Advancement of Science
2006-Present Member, International Society for Eye Research
2004-Present Member, Sinapsa (Slovenian Association for Neuroscience)
1996-Present Member, Association for Research in Vision and Ophthalmology
1992-Present Member, Society for Neuroscience
Edward M Levine, PhD2004-Present Member, Editorial Board, Developmental Dynamics
Nick Mamalis, MD2012 Moderator, Cataract Symposium, American Society of Cataract and Refractive Surgery,
Chicago, Illinois
2007-Present Editor, Journal of Cataract and Refractive Surgery
Member, Executive Committee, American Society of Cataract and Refractive Surgery
1998-Present Editorial Board, Review of Ophthalmology
1997-Present Member, American Society of Cataract and Refractive Surgery Cataract Clinical Committee
1989-Present Member, Board of Directors, National Society to Prevent Blindness: Utah Affiliate
1988-Present Volunteer, Research to Prevent Blindness Ophthalmological Associate
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Robert E Marc, PhD 2012 Member, Editorial Board, Journal of Comparative Neurology, Society for Neuroscience
Member, Association for Research in Vision and Ophthalmology
Member, American Association for the Advancement of Science
Member, Optical Society of America
Majid Moshirfar, MD 2012-Present Member, Editorial Board, Oman Journal of Ophthalmology
Member, Editorial Board, Journal of Cataract and Refractive Surgeons Consultation Section
2011-Present Member, Editorial Board, Scientific World Journal
2009-Present Member, Editorial Board, International Advisory Board, Middle East African Journal of Ophthalmology
Richard A Normann, PhD Host, 40th Neural Interfaces Conference, Salt Lake City, Utah
Randall J olson, MD 2012 Executive Editor, American Journal of Ophthalmology
Editorial Board, Ophthalmologica
Bhupendra C K Patel, MD, FRCS, FRC 2007-Present Chief Section Editor, Plastic Surgery, British Journal of Ophthalmology
2006-Present Chief Section Editor, Plastic Surgery, EYE
2005-Present Chief Co-editor, ORBIT
2003-Present Member, Editorial Board, Evidence Based Eye Care
2002-Present Editor, USA ORBIT
2000-Present Member, Editorial Board, Aesthetique
1999-Present Member, Editorial Board, Journal of Cranio-Maxillofacial Trauma
1996-Present Member, Medical Advisory Board, American Society of Ocularists
1991-Present Member, Editorial Board, Abstracts from the Literature for Ophthalmic, Plastic, and Reconstructive Surgery
Geoffrey Tabin, MD 2006-Present Editor, Stedman’s Medical Dictionary
Monica Vetter, PhD 2011-present Member, Scientific Advisory Board, “Catalyst for a Cure 2,” Glaucoma Research Foundation
Albert T Vitale, MD 2011-Present Member, University of California, Los Angeles, UCLA Center for the Health Sciences, International Workshop on Uveitis in Children, Jules Stein Eye Institute
2009-Present Member, American Uveitis Society, Standardization of Uveitis Nomenclature (SUN) Working Group
2009-Present Member, American Uveitis Society Executive Committee, Secretary for Internal Affairs
2006-Present Member, Editorial Board, Editorial and Writing Committee for Practicing Ophthalmologists Committee, American Academy of Ophthalmology
Editor, American Academy of Ophthalmology Basic Science Course
Editor, Intraocular Inflammation, Uveitis, and Tumors, Focal Points
2005-Present Contributing Editor and Writing Committee Member, “Intraocular Inflammation and Uveitis, BCSC 9, Basic Science Course,” American Academy Ophthalmology
Section Editor, Uveitis and Intraocular Tumors, Focal Points, American Academy of Ophthalmology
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Judith E A Warner, MD 2004-Present Member, Editorial Board, Neuro-Ophthalmology
Liliana Werner, MD, PhD 2012 Chief Judge, Annual Video Festival, American Society of Cataract and Refractive
Surgery
Member, Scientific Advisory Board, Powervision Inc.
2012-present Board Member, Institutional Review Board, University of Utah 2012
2011-present Chair, Continuing Medical Education Advisory Committee, American Society of Cataract and Refractive Surgery 2010-Present
2010-present Chair, Sequenom, Inc., Clinical Advisory Board
2009-present Member of the Scientific Advisory Board of Powervision Inc., USA
2009-present Member, American Academy of Ophthalmology Ophthalmic News & Education Network
2004-Present Member, Editorial Board, Journal of Cataract & Refractive Surgery
2004-Present Member, Editorial Board, EyeWorld Magazine
2003-present Member, Continuing Medical Education Advisory Committee, American Society of Cataract and Refractive Surgery
Barbara M Wirostko, MD2012 Member, Advisory Board and Chairperson/ Moderator, 4th Ocular Diseases and Drug Discovery Conference, Las Vegas, Nevada
2011-Present Chief Medical Officer Retained Consultant, Altheos, Inc.
Executive Team Member, Lead Clinical Development Program & Glaucoma Strategy, Novel Rho Kinase Inhibitor, Currently in Phase 2
Ophthalmology Consultant and Member, Medical Advisory Board, Premier Research LTD., Wokingham, United Kingdom; expert Advisor, Ophthalmology Drug Development Clinical Research Protocols and Strategy
Chief Medical Officer and Strategic Advisory Board Member, SKS Biotech Incubator Investigating Novel Delivery Methods for Ophthalmic Diseases: AMD & Glaucoma
Member/Advisor, Entrepreneurial Faculty Scholars, Entrepreneurial Opportunities and Clinical Research, University of Utah
Member, Scientific Advisory Committee for Glaucoma Research Foundation, San Francisco, California
2011 Advisory Board Member, Chairperson, Moderator, 3rd Ocular Diseases & Drug Discovery Conference, Boston, Massachusetts
2010-Present Member, California Institute for Regenerative Medicine Scientific and Medical Research Grants Review Working Group, Editorial Board, Acta Ophthalmologica
2009-Present America Top Ophthalmologist, Journal of Consumer Research
2007-Present Associate Editor and Peer Reviewer, Acta Ophthalmologica
Jun yang, PhD 2012 Member, Scientific Review Committee, Fight for Sight, New York, New York
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RETINA Title: Follow-up Evaluation of Participants from a Prior Study of Implants of Encapsulated Human NTC-201 Cells Releasing Ciliary Neurotrophic Factor (CNTF) for Atrophic Macular Degeneration
Sponsor: Lowy Research InstitutePrincipal Investigator: Paul S Bernstein, MD, PhD
Title: Age-related Eye Disease Study 2 (AREDS2): A Multi-center, Randomized Trial of Lutein, Zeaxanthin, and Omega-3 Long-Chain Polyunsaturated Fatty Acids (Docosahexaenoic Acid [DHA] and Eicosapentaenoic Acid [EPA]) in Age-related Macular Degeneration
Sponsor: NIH/NEIPrincipal Investigator: Paul S Bernstein, MD, PhD
Title: Home-vision Monitoring in AREDS2 for Progression to Neovascular AMD Using the ForeseeHome Device
Sponsor: Notal Vision, Ltd. Principal Investigator: Paul S Bernstein, MD, PhD
Title: Genetics Protocol of Macular Telangiectasia Type 2: The MacTel Study
Sponsor: Lowy Research Foundation Principal Investigator: Paul S Bernstein, MD, PhD
Title: Utah Center for the Collaborative Study of the Role of the Macular Pigment Carotenoids in the Pathogenesis and Treatment of MacTel
Sponsor: Lowy Research Institute Principal Investigator: Paul S Bernstein, MD, PhD
Title: A Phase 2, Randomized, Double-masked, Controlled Trial to Establish the Safety and Efficacy of Intravitreous Injections of E10030 (Anti-PDGF Pegylated Aptamer) Given in Combination with LUCENTIS® in Subjects with Neovascular Age-related Macular Degeneration
Sponsor: Ophthotech, Inc.Principal Investigator: Paul S Bernstein, MD, PhD
Title: Raman Measurement of Macular Carotenoid Pigments in the Human Retina
Sponsor: NIH/NEIPrincipal Investigator: Paul S Bernstein, MD, PhD
Title: Macular Pigment Imaging in Infants Using the RetCam®
Sponsor: Abbott Laboratories, Inc. Principal Investigator: Paul S Bernstein, MD, PhD
Title: A Phase II Multiple Site, Randomized, Placebo-controlled Trial of Oral Valproic Acid for Retinitis Pigmentosa
Sponsor: National Neurovision Research Institute Principal Investigator: Paul S Bernstein, MD, PhD
Title: National Ophthalmic Genotyping and Phenotyping Network, Stage 1 — Creation of DNA Repository for Inherited Ophthalmic Diseases (eyeGENE)
Sponsor: NIH/NEI Principal Investigator: Paul S Bernstein, MD, PhD
Title: Phase 2 Multicenter, Randomized Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of GSK933776 in Adult Patients with Geographic Atrophy Secondary to Age-related Macular Degeneration
Sponsor: GlaxoSmithKline Principal Investigator: Paul S Bernstein, MD, PhD
Title: Prospective Multicenter Post-approval Study of VisionCare’s Implantable Miniature Telescope in Patients with Severe to Profound Central Vision Impairment Associated with End-stage Age-related Macular Degeneration
Sponsor: VisionCare Ophthalmic Technologies Principal Investigator: Majid Moshirfar, MD
Title: A Multicenter Study of the Efficacy and Safety of the Human Anti-TNF Monoclonal Antibody Adalimumab as Maintenance Therapy in Subjects Requiring High-dose Corticosteroids for Active Non-infec-tious Intermediate-, Posterior-, or Pan-uveitis
Sponsor: Abbott Laboratories, Inc. Principal Investigator: Albert T Vitale, MD
Title: A Multicenter Study of the Efficacy and Safety of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects with Inactive Non-infectious Intermediate-, Posterior-, or Pan-uveitis
Sponsor: Abbott Laboratories, Inc. Principal Investigator: Albert T Vitale, MD
Title: A Multicenter Open-label Study of the Long-term Safety and Efficacy of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects with Non-infectious Intermediate-, Posterior-, or Pan-uveitis Incorporating Amendment 1
Sponsor: Abbott Laboratories, Inc. Principal Investigator: Albert T Vitale, MD
Title: Long-term Followup of Patients Participating in the Multicenter Uveitis Steroid Treatment (MUST) Trial
Sponsor: NIH/NEI Principal Investigator: Albert T Vitale, MD
CATARACT AND GLAUCoMA Title: A Prospcetive Multicenter Clinical Study to Evaluate the Saftey and Effectiveness of the Synchrony® Dual Optic Intraocular Lens in Patients Undergoing Cataract Extraction
Sponsor: Visiogen, Inc.Principal Investigator: Alan S Crandall, MD
Title: A Study of Phenylephrine HCl’s and Ketorolac Tromethamine’s Ability, Alone and in Combination, to Maintain Mydriasis and Relieve Pain and Inflammation in Subjects Undergoing Unilateral Cataract Extraction with Lens Replacement (CELR)
Sponsor: Omeros CorporationPrincipal Investigator: Alan S Crandall, MD
Title: Communication about Glaucoma and Patient Outcomes
Sponsor: NIHPrincipal Investigator: Jason Goldsmith, MD
CORNEA Title: Cornea Donor Study
Sponsor: JAEB Center for Health Research/NEIPrincipal Investigator: Mark D Mifflin, MD
Title: Effect of Corneal Graft Preservation Time on Long-term Graft Success Study (CPTS)
Sponsor: NIH/NEIPrincipal Investigator: Mark D Mifflin, MD
NEURo-oPHTHALMoLoGy Title: Case-crossover Study of PDE5 Inhibitor Exposure as a Potential Trigger Factor for Acute NAION
Sponsor: Pfizer, Inc. Principal Investigator: Kathleen B Digre, MD
Currently, more than 50 clinical research trials are being carried out at the Moran Eye Center
C L I N I C A L T R I A L STitle: A Mulitcenter, Double-blind, Randomized, Placebo-controlled Study of Weight-reduction and/or Low-sodium Diet Plus Acetazol-amide vs Diet Plus Placebo in Subjects with Idiopathic Intracranial Hypertension with Mild Visual Loss
Sponsor: NIH/NEI Principal Investigator: Kathleen B Digre, MD
Title: Phase I Open-label, Dose-escalating Trial of QPI-1007 Delivered by Intravitreal Injection to Patients with Optic Nerve Atrophy and Acute Non-arteritic Anterior Ischemic Optic Neuropathy
Sponsor: Quark Pharmaceuticals, Inc. Principal Investigator: Bradley J Katz, MD, PhD
Title: Predictive Value of Optic Nerve MRI Measurements at Onset of Optic Neuritis for Two-year MS Outcomes
Sponsor: Cummings FoundationPrincipal Investigator: Bradley J Katz, MD, PhD
Title: Thin-film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Patients with Migraine
Sponsor: Axon OpticsPrincipal Investigator: Bradley J Katz, MD, PhD
PEDIATRIC oPHTHALMoLoGy Title: Telemedicine Approaches to Evaluating Acute-phase ROP (The e-ROP Study)
Sponsor: NIH/NEI Principal Investigator: Robert O Hoffman, MD
Title: Postnatal Growth and Retinopathy of Prematurity Model Development Study (G-ROP)
Sponsor: NIH/NEI Principal Investigator: Robert O Hoffman, MD
Title: Ambylopia Treatment Study (ATS)15: Increasing Patching for Ambylopia
Sponsor: JAEB Center for Health Research/NIHPrincipal Investigator: Marielle Young, MD
Title: Pediatric Cataract Surgery Outcomes Registry
Sponsor: Jaeb Center for Health Research/NIHPrincipal Investigator: Marielle Young, MD
INVESTIGAToR-SPoNSoRED CLINICAL RESEARCH PRoJECTS Title: Collagenase Assisted Deep Anterior Lamellar Keratoplasty
Principal Investigator: Balamurali K Ambati, MD, PhD, MBA
Title: Topical Clinical Interventions Against Stargardt Macular Dystrophy: DHA Supplementation in Patients with STGD3
Principal Investigator: Paul S Bernstein, MD, PhD
Title: Effects of Maternal Nutrition and Intrauterine Growth Restric-tion on Infant Carotenoid Status
Principal Investigator: Paul S Bernstein, MD, PhD
Title: IIH Without Papilledema Exists
Principal Investigator: Kathleen B Digre, MD
Title: Evaluation of Optic Neuropathies with Imaging
Principal Investigator: Kathleen B Digre, MD
Title: Assessment of Photophobia in Moran Eye Center Patients
Principal Investigator: Kathleen B Digre, MD
Title: Genetic Associations in Preterm Infants at Risk of Retinopathy of Prematurity
Principal Investigator: Mary Elizabeth Hartnett, MD
Title: Genetics of Pediatric Retinal Disorders
Principal Investigator: Mary Elizabeth Hartnett, MD
Title: Preeclampsia and Retinopathy of Prematurity
Principal Investigator: Mary Elizabeth Hartnett, MD
Title: Retrospective Analysis of Neurofibromatosis Type 1-associated Optic Glioma Outcome after Treatment
Principal Investigator: Robert O Hoffman, MD
Title: Measurement of Critical Flicker Fusion Frequency
Principal Investigator: Bradley J Katz, MD, PhD
Title: Proteomics and Genomics of Giant Cell Arteritis
Principal Investigator: Bradley J Katz, MD, PhD
Title: Genomic Analysis of Non-arteritic Anterior Ischemic Optic Neuropathy
Principal Investigator: Bradley J Katz, MD, PhD
Title: Optic Nerve Drusen: Clinical Characterization and Genetic Mapping
Principal Investigator: Bradley J Katz, MD, PhD
Title: Treatment of Giant Cell Arteritis with Antibiotics
Principal Investigator: Bradley J Katz, MD, PhD
Title: Screening Device for Diseases of the Optic Nerve
Principal Investigator: Bradley J Katz, MD, PhD
Title: Retrospective Study of Descement’s Stripping Automated Endothelial Keratoplasty Outcomes
Principal Investigator: Mark D Mifflin, MD
Title: Topical Proparacaine vs Tetracaine in Photorefractive Keratectomy (PRK)
Principal Investigator: Majid Moshirfar, MD
Title: Topical Proparacaine vs Tetracaine in Laser Assisted in Situ Keratomileusis (LASIK)
Principal Investigator: Majid Moshirfar, MD
Title: Biomechanical Changes in the Cornea after Laser Assisted in situ Keratomileusis (LASIK) and Photorefractive Keratectomy (PRK)
Principal Investigator: Majid Moshirfar, MD
Title: Impact of AcrySof Glistenings on Visual Quality
Principal Investigator: Randall J Olson, MD
Title: Refractive Index and Pseudophakic Dysphotopsia
Principal Investigator: Randall J Olson, MD
Title: Quality of Life Assessment in an Indigent Population Following Cataract Surgery
Principal Investigator: Jeff Pettey, MD
Title: Experience in an Ophthalmology Clinic for Homeless Patients
Principal Investigator: Brian Stagg, MD
Title: Efficacy of Pars Plana Vitrectomy and Sub-retinal Tissue Plasminogen Inhibitor for the Treatment of Sub-macular Hemorrhage
Principal Investigator: Michael P Teske, MD
Title: Non-interventional Cross-sectional Observational Study Assessing Various Novel Vascular and Diagnostic Parameters and their Relationship to Glaucoma
Principal Investigator: Barbara M Wirostko, MD
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Balamurali K Ambati, MD, PhD, MBA06/13/2012 Patent Pending: “Nitinol Ring-Capsulotome,” U-5400.
11/29/2012 Released to Inventor: “The Poodle-Cat,” U-5510.
12/05/2012 Patent Pending: “Raver2 as Controller of sFlt-1 and Vascular Demarcations,” U-5512.
Margaret DeAngelis, PhD7/31/2012 Patent: “Methods for Detecting Neovascular Age-related Macular Degeneration,” US8232056.Patent filed as a result of association studies performed in the DeAngelis laboratory that linked genetic variants to risk of age-related macular degeneration. US Patent Application No. 13/115,912.
Gregory S Hageman, PhD; yingbin Fu, PhD9/2012 Patent: “Methods of Diagnosing and Treating Vascular Associated Maculopathy and Symptoms Thereof.” University of Utah Research Foundation, WO 2012/125872.
Patents Pending: “Assessing Susceptibility to Vascular Disorders (ParAllele).” Washington, DC. Patent and Trademark Office.
“Binding of Complement Factor H to C-Reactive Protein (CFH-CRP Binding).” Washington, DC. Patent and Trademark Office.
“Biomarkers Associated With Age-related Macu-lar Degeneration (DIGE & MALDI Biomarkers).” Washington, DC. Patent and Trademark Office.
“Diagnostics and Therapeutics for Arterial Wall Disruptive Disorders (AMD to AAA).” Washington, DC. Patent and Trademark Office.
“Genes and Polymorphisms Associated with AMD (ParAllele).” Washington, DC. Patent and Trademark Office.
“Methods and Reagents for Treatment and Diagnosis of Vascular Disorders and Age-related Macular Degeneration (CFHR1/R3 Deletion).” Washington, DC. Patent and Trademark Office.
“Predicting AMD with SNPs Within or Near C2, Factor B, PLEKHA1, HTRA1, PRELP, or LOC387715 (ParAllele).” Washington, DC. Patent and Trademark Office.
“RCA Locus Analysis to Assess Susceptibility to AMD and MPGNII.” Washington, DC. Patent and Trademark Office.
“Variants In Complement Regulatory Genes Predict Age-related Macular Degeneration (CFB/C2 Diagnostics).” Allikmets RL, Hageman GS, Dean MC, Gold AM. Washington, DC. Patent and Trademark Office.
Bryan W Jones, PhD; Robert E Marc, PhD2012Patent Pending: “Oncological Application of Computational Molecular Phenotyping.”
Bradley J Katz, MD, PhD2012Patent Pending: “Methods, Systems, and Apparatus for Reducing the Frequency and/or Severity of Photophobic Responses or for Modulating Circadian Cycles.” Founder and CEO of Axon Optics, www.axonoptics.com
Dr. Bradley J Katz, MD, PhD, joined with Tecport Optics to develop a ground-breaking optical interference filter coating process for plastic spectacle lenses. The process blocks the specific wavelengths of light that have been implicated as the cause of photophobic symptoms, particularly those associ-ated with triggering and exacerbating debilitating migraine headaches. The University of Utah has registered the existing proprietary property.
David Krizaj, PhD 2012Salcantay Vision Solutions, LLC CEO
2012Asha Vision, LLC, Founder and CEO
Technology Commercialization and Intellectual Property/PatentsTechnology Commercialization and Intellectual Property/PatentsTechnology Commercialization and
J o H N A . M o R A N E y E C E N T E R
2012-2013Patents, Patents Pending, Industry & Technology, Technological, and Other Scientific Innovations
“Saving Sight by Curing Glaucoma.” Dr. David Krizaj, PhD, and Asha Vision received a Technology Commercialization and Innovation Program (TCIP) grant from the State of Utah.
2012Center for Translational Medicine (CTM), University of Utah, member.
5/10/2012 Patent Pending: “Role of TRPV4 Antagonists in Ocular Disease.” Docket No. 00846-U5301.PROV. D Krizaj, DA Ryskamp, P Barabas. Inventor of a novel method for treatment of glau-coma and other ocular diseases associated with abnormal mechanical environment within the eye. the method has been validated in animal models and has the potential for a wide impact on clinical care, as there are currently no treat-ments that regulate intraocular pressure and protect retinal ganglion neurons in glaucoma.
10/16/2012 Patent Pending: “Mechanosensory Channel Antagonists in Glaucomatous Neuroprotection,” D 00846-US01.Krizaj, DA Ryskamp, P Barabas.
Richard A Normann, PhD2012 Richard A Normann, PhD, performed the first human implant of Utah electrode arrays in severed nerves of an upper limb amputee (project supported by Defense Advanced Research Projects Agency). The project sets the stage for work in blind human volunteers.
Randall J olson, MD2012 Patent Submitted: “A Vision Correction System to Minimize Intraocular Lens Rotation.”
Patents Pending: “A Vision Correction System,” patent 5087
Hypodermic Needle System and Method to Reduce Infection.” patent 4826
Liliana Werner MD, PhD1996-present “Procédé de revêtement de matériaux et produits ainsi obtenus. Téflon AF pour implant intraoculaire.”Legeais JM, Legeay G, Werner L, renard G. French patent number FR 9604267, registered on April 4th, 1996, Paris.
Barbara M Wirostko, MD2011-presentBarbara M Wirostko, MD, is co-founder and Chief Scientific Officer of Jade Therapeutics, LLC Drug Development Company focusing on developing sustained delivery drugs and prod-ucts in ophthalmic areas of high unmet need utilizing a novel crosslinked hyaluronic acid biodegradable polymer.
4/2012; 9/2012 Jade Therapeutics is the recipient of two prestigious entrepre-neurial grants: “Technology Commercialization and Innovation Program” (TCIP) grants through USTAR, $40,000 each.
8/2012–2/2013The TCIP (formerly “Centers of Excellence”) is a state-funded grant and mentoring program originally developed by the Utah Legislature in 1986 to help accelerate the process of taking cutting-edge technologies developed at Utah’s colleges and universities to market. PI: Barbara M Wirostko, MD, 10 percent effort.
2012US army medical research and materiel command clinical and Rehabilitative Medicine Research Program Research Area Directorate 5. ATTN: MCMR-RTR, 504 Scott Street BLDG 722, Fort Detrick, MD 21702. Submitted 2012; awarded 2013.
“Treatment of Corneal Epithelial Wound Using A Novel Sustained Drug Delivery of Human Growth Hormone.” Dr. Wirostko is providing strategic and technical oversight without compensation. CRADA in place for non-GLP proof of concept preclinical work to occur at USAISR using novel burn models NOT included in the BAA proposal. Jade will supply the needed drug loaded delivery materials.
PI: Col. Anthony Johnson, MD, Task Area Manager of US Army Institute of Surgical Research; CO-I: Barbara M Wirostko, MD, 5 percent effort.
Title/#/ Solicitation Date: Internal Core Funds AIBS NO:120336. CRADA in place between Jade and USAIRS for this preclinical work.
2012Barbara M Wirostko, MD, through Jade, has submitted an NSF SBIR-Phase I Solicitation FY-2013; 12-605 (BM3). Grant has been awarded in 2013.
2011-2012Patents Pending filed by Jade Therapeutics, Inc.:
Application #1 US Patent No. 61/62, 4730 (Filed 2011)“Corneal Wound Healing.”
Application #2 US Patent No. 61/58, 1845 (Filed 2012) “Dermal Wound Healing.”
Application # 3 Provisional US Patent No. 3246-005 (Filed 2012) “Corneal Re Innervation.”
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January 11 Marielle Young, MD The Diagnosis & Management of Ocular Torsion
Lloyd Williams, MD South Sudan
January 18 Krista Kinard, MD, Resident Restriction vs Dysinnervation
January 25 Mark Michelson, MD, Associate Clinical Professor Pseudophakic Accommodation: of Ophthalmology & Director of Cornea, University Another Perspective of Alabama, Birmingham
February 1 Alan S Crandall, MD Femtosecond & Ultrachopper
February 8 Balamurali K Ambati, MD, PhD, MBA Soluble FLT-1: From Wellspring of Avascularity to Springboard for Anti-Angiogenics
Brian Zaugg, MD, Resident Ocular Lymphoma
February 15 Tony Adamis, VP & Global Head of Ophthalmology Next Steps in AMD at Genetech
February 22 Jason Goldsmith, MD Cognitive Errors in Medical Decision Making
February 29 Barbara M Wirostko, MD Research Opportunities at the Moran
Joyce Mitchell, Biomedical, University of Utah clinical cohort Finding with the FUrtHer System
March 7 Jim Bell, MD, Resident Acute Unilateral Vision Loss with Stiffness
Angela Peters, MD, Neurology Resident NARP: Neurogenic Muscle Weakness, Ataxia & Retinitis Pigmentosa
March 14 Gregory S Hageman, MD A New Era in Our Understanding of Age-related Macular Degeneration
March 21 Dr. Sanduk Ruit, Founder of the Tilganga Eye Overcoming Cataract Blindness in the Institute & Lead Partner of Moran’s International Developing World Division of ophthalmology
March 28 Michael Varner, MD, Professor, University of Utah Personalized Health Care OBGYN
April 11 Kathleen B Digre, MD, Moran/Eccles Library Using Library Resources to Enhance your Career
April 18 Dan Bettis, MD Unexplained Vision Loss
April 25 Todd Cahoon, Medical Student, University of Utah COMP.Ang1-induced Vascular Normalization Enhances Visual Structure and Function in Murine Type 1 Diabetic Retinopathy
May 9 Sabine Fuhrmann, PhD Extracellular Signals Regulating eye Development
May 23 Leah Owen, MD, Resident Bad Eyes & Bad Ears Run in the Family— Early Onset Vision and Hearing Loss
May 30 Zachary Joos, MD Intern Floaters, Fatigue, and Forgotten Insulin
Briana Sawyer, Genetic Counselor, Introduction to Genetic Counseling ophthalmology Services
June 6 Gene Kim, MD Confocal Microscopy of the Cornea: Clinical Applications & Standardizing Data Acquisition + Neuroretinitis vs. Optic Neuritis
June 13 Maylon Hsu, MD DSAEK Ultra Thin Grafts & Complication & Outcomes of Challenging Cases + A Big Blind Spot
June 20 Tom Oberg, MD, Resident Cryoprin Associated Periodic Syndromes & the Eye + Gial Cell Arteritis: Spectrum and Future
July 18 Nick Behunin, MSIV, Keratoconus Treatments University of Utah
Scott Butikofer, MSIV, Enterobacter Cloacae Post-surgical University of Washington SOM Endophthalmitis
Rachel Simpson, MSIV, Ocular Complications of Diabetes University of Arizona COM
D A T E P R E S E N T E R T o P I C o R T I T L E
2012Grand Rounds
July 25 Lucas Lenci, MSIV, Orbital Cellulitis University of Missouri Columbia SOM
John Bennion, Ocular Manifestations of Inflammatory West Virginia University Health Sciences Bowel Disease
Gary Nelson, MD, Neurology Resident Third Nerve Palsy
August 8 Alan S Crandall, MD Update on Minimally Invasive Glaucoma Surgery
August 15 Steve Christensen, MSIV, University of Utah Keratometric Changes after Refractive Surgery
Gavin Roddy, MSIV, Adult Stem/Progenitor Cells & Their Secreted Texas A&M Health Sciences COM Proteins for the Treatment of Ocular Disease
August 22 Andrew Rodenburg, MSIV, Ophthalmology: The Digital Age University of North Dakota SOM
Chris Smith, MSIV, Comparison of Noncontact & Contact Confoval University of Texas Medical Branch Microscopy after Descemet’s Stripping Automated Endothelial Keratoplasty
August 29 Zach Oakey, MSIV, University of Utah Keratoconus, Anatomy, Pathology, and Case Presentation
Bryce Radmall, MSIV, University of Utah Vision of the Homeless: The Moran Eye Center at the Fourth Street clinic
September 5 Paul S Bernstein, MD, PhD, & Brianna Sawyer, Genetic Counseling in Ophthalmology Genetic Counselor, Ophthalmology Services
September 12 Ronnie Bhola, MD Trocar Assisted Sutureless Scleral Fixation Visiting Physician, Trinidad/Tobago of Posterior Chamber IOL Viscodissection Diabetic Delamination
September 19 Chad Jackson, MSIV, University of Kentucky COM Birdshot or Not? Birdshot Retinachoroidopathy
Jason Hooten, MSIV, Terrien’s Marginal Degeneration Case University of Washington SOM Presentation & Discussion
Peter Ririe, MSIV, University of Texas SW a novel model for Studying Fibroblast Medical Center at Dallas Migration through Fibrin Matricies
September 26 Zachary Joos, MD Clinical Case: A twenty-year-old with encephalopathy & Scotoma
October 10 Brian Stagg, MD, Intern Pre-operative Medical Assessment of Patients Undergoing eye Surgery
Allison Jarstad, MSIV, Pacific Northwest Child with Rapidly Progressive Proptosis University of Health Sciences
October 17 Bhupendra C K Patel, MD, FRCS, FRC Procedures for Ophthalmologists: Part 1. Video Presentation with Tips
October 24 Trent Richards, MD Patient with Multiple Branch Retinal artery occlusions
October 31 Brian Zaugg, MD, Resident Intraoperative Floppy Iris Syndrome
November 7 Randall J Olson, MD What Does Optical Quality Mean and What Can It Tell Us
November 14 Jim Bell, MD Red Eyes & Intubated: A Uveitic Curiosity
Chung Lee, MD, Neurology Resident Word Blindness
November 28 Nick Mamalis, MD Pathology of PX
Liliana Werner, MD, PhD IOL/CTR Subluxation/Dislocation
Jeff Pettey, MD Sleep Deprivation
December 5 Dan Bettis, MD Wait…Can you Fake That?
December 12 Peter Barabas, PostDoc in Krizaj Lab Mouse Models of STGD3
D A T E P R E S E N T E R T o P I C o R T I T L E
2012Grand Rounds
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Advances in Experimental Medicine & BiologyXing W, Akopian A, Krizaj D. Trafficking of presynaptic PMCA signaling complexes in mouse photoreceptors requires Cav1.4 alpha1 subunits. Adv Exp Med Biol 2012; 723:739-744
American Journal of Human GeneticsTantravahi SK, Williams LB, Digre KB, Creel DJ, Smock KJ, DeAngelis M, Clayton FC, Vitale AT, Rogers GM. An inherited disorder with splenomegaly, cytopenias, and vision loss. Am J Hum Genet 2012; 201;158, 475-81
American Journal of Ophthalmology Lim JH, Wickremasinghe SS, Xie J, Chauhan DS, Baird PN, Robman LD, Hageman GS, Guymer RH. Delay to treatment and visual outcomes in patients treated with anti-vascular endothelial growth factor for age-related macular degeneration. Am J Ophthalmol 2012; 153(4), 678-86
Dhital A, Spalton DJ, Goyal S, Werner L. Calcification in hydrophilic intraocular lenses associated with injection of intraocular gas. Am J Ophthalmol 2012 Jun; 153(6):1154-60.e1
American Journal of Pathology Wang H, Byfield G, Jiang Y, Smith GW, McCloskey M, Hartnett ME. VEGF-mediated STAT3 activation inhibits retinal vascularization by down-regulating local erythropoietin expression. Am J Pathol 2012; 180(3), 1243-53
Archives of Biochemistry and Biophysics Vachali P, Li B, Nelson K, Bernstein PS. Surface plasmon resonance (SPR) studies on the interactions of carotenoids and their binding proteins. Arch Biochem Biophys 2012; 519(1), 32-37
Archives of OphthalmologyFrandsen JE, Llop S, Digre KB, Bernstein PS, Sharifzadeh M, Warner JE, Gellerman W, Katz BJ. Quantification of macular carotenoids using autofluorescence imaging in patients with photosensitive migraine and benign essential blepharospasm. Arch Ophthalmol 2012; 130(2), 259-60
Bourne R, Price H, Stevens G, Hartnett ME, GBD Vision Loss Expert Group. Global burden of visual impairment and blindness. Arch Ophthalmol 2012; 130(5), 645-7
Wu C, Lofqvist C, Smith L, VanderVeen DK, Hellstrom A, Hartnett ME, WINROP Consortium. Importance of early postnatal weight gain for normal retinal angiogensis in very preterm Infants. Arch Ophthalmol 2012; 1-8
Kopplin LJ, Przepyszny K, Schmotzer B, Rudo K,
Babineau DC, Patel SV, Verdier DD, Jurkunas U, Iyengar SK, Lass JH, Fuchs Endothelial Corneal Dystrophy Genetics Multi-center Study Group (Mifflin MD). Relationship of Fuchs endothelial corneal dystrophy severity to central corneal thickness. Arch Ophthalmol 2012; 130(4), 433-439
Espandar L, Bunnell B, Wang GY, McBride C, Moshirfar M. Adipose-derived stem cells on hyaluronic acid-derived scaffold: a new horizon in bioengineered cornea. Arch Ophthalmol 2012; (6), 213-8
Digre K, Warner J, Katz B, Gilman J. Imaging characteristics of myelinated retinal nerve fiber layer. Arch Ophthalmol 2012
British Journal of Ophthalmology Cherepanoff S, Killingsworth MC, Zhu M, Nolan T, Hunyor AP, Young SH, Hageman GS, Gillies MC. Ultrastructural and clinical evidence of subretinal debris accumulation in type 2 macular telangiectasia. Br J Ophthalmol 2012
Zore M, Harris A, Tobe LA, Siesky B, Januleviciene I, Behzadi J, Amireskandari A, Egan P, Garff K, Wirostko BM. Generic medications in ophthalmology. Br J Ophthalmol 2012 Nov 9
British Medical JournalWirostko BM, Tressler C, Hwang LJ, Burgess G, Laties AM. ocular safety of sildenafil citrate when administered chronically for pulmonary arterial hypertension: results from a phase 3, randomised, double-masked, placebo-controlled trial and 2 year open label extension. British Medical Journal 2012 Feb 21; 344:e554
Canadian Journal of Ophthalmology Sorensen T, Chan CC, Bradley M, Braga-Mele R, olson RJ. A comparison of cataract surgical practices in Canada and the United States. Can J Ophthalmol 2012; 47(2),131-9
Cell Tarallo V, Hirano Y, Gelfand BD, Dridi S, Kerur N, Kim Y, Cho WG, Kaneko H, Fowler BJ, Bogdanovich S, Albuquerque RJ, Hauswirth WW, Chiodo VA, Kugel JF, Goodrich JA, Ponicsan SL, Chaudhuri G, Murphy MP, Dunaief JL, Ambati BK, Ogura Y, Yoo JW, Lee DK, Provost P, Hinton DR, Nunez G, Baffi JZ, Kleinman ME, Ambati J. DICER1 loss and Alu RNA induced age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell 2012; 149(4),847-59
Cerebral CortexJeffs J, Federer F, Ichida JM, and Angelucci A. High-resolution mapping of anatomical connections in marmoset extrastriate cortex reveals a complete representation of the visual field bordering dorsal V2. Cerebral Cortex 2012; doi:10.1093
Clinical & Experimental OphthalmologyShoshani Y, Harris A, Shoja MM, Arieli Y, Ehrlich R, Primus S, Ciulla T, Cantor A, Wirostko B, Siesky BA. Impaired ocular blood flow regulation in patients with open angle glaucoma and diabetes. Clin Experiment Ophthalmol 2012 Sep; 40(7):697-705
Clinical OphthalmologyChristiansen SM, Mifflin MD, Edmonds JN, Simpson RG, Moshirfar M. Astigmatism induced by conventional spherical ablation after PRK and LASIK in myopia with astigmatism <1.00 D. Clin Ophthalmol 2012; 6,2109-17
Khakshoor H, Moshirfar M, Simpson RG, Garaee H, Vejdani AH, Christiansen SM, Edmonds JN, Behunin NL. Anesthetic keratopathy presenting as bilateral Mooren-like ulcers. Clin Ophthalmol 2012; (6), 1719-22
Simpson RG, Moshirfar M, Edmonds JN, Christiansen SM, Behunin N. Laser in situ keratomileusis in patients with collagen vascular disease: a review of the literature. Clin Ophthalmol 2012; (10), 2147
Simpson RG, Moshirfar M, Edmonds JN, Christiansen SM. Laser in-situ keratomileusis in patients with diabetes mellitus: a review of the literature. Clin Ophthalmol 2012; (6), 1665-74
Mifflin MD, Leishman LL, Christianse SM, Sikder S, Hus M, Moshirfar M. Use of lotoprednol for routine prophylaxis after photorefractive keratectomy. Clin Ophthalmol 2012; (6), 653-9
Huse M, Hereth WL, Moshirfar M. Double-pass microkeratome technique for ultra-thin graft preparation in Descemet’s stripping automated endothelial keratoplasty. Clin Ophthalmol 2012; (6), 425-432
Moshirfar M, Ollerton A, Semnani RT, Hau M. Radial keratotomy associated endothelial degeneration. Clin Ophthalmol 2012; (6), 213-8
Cornea Cho YK, Uehara H, Young JR, Archer B, Ambati BK. Pretreatment in a murine penetrating keratoplasty and suture model. Cornea 2012
Moshirfar M, Khalifa YM, Davis D, Fenzl CR, Espandar L, Change JC, Mamalis N, Mifflin MD. Descement stripping automated endothelial keratoplasty using donor corneas with previous laser in situ keratomileusis or photorefractive keratectomy: a case series and donor cap histopathology. Cornea 2012; 31(5), 533-537
Louttit MD, Kopplin LJ, Igo RP, Fondran JR, Tagliaferri A, Bardenstein D, Aldave AJ, Croasdale CR, Price MO, Rosenwasser GO, Lass JH, Iyengar SK, FECD Genetics Multi-center Study Group (Mifflin MD). A multicenter study
A sample of more than 200 published and presented materials by Moran faculty members between January 1 and December 31, 2012
P U B L I S H E D R E S E A R C Hto map genes for Fuchs endothelial cornea dystrophy: baseline characteristics and heritability. Cornea 2012; 31(1), 26-35
Sugar A, Montoya MM, Beck R, Cowden JW, Dontchev M, Gal RL, Kollman C, Malling J, Mannis MJ, Tennant BA, Cornea Donor Study Investigator Group (Mifflin MD). Impact of the cornea donor study on acceptance of corneas from older donors. Cornea 2012; 31(12), 1441-1445
Calvo CM, Sikder S, Mamalis N, Mifflin MD. Linear interstitial keratitis: a distinct clinical entity revisited. Cornea 2012; 31(12), 1500-1503.
Stulting RD, Sugar A, Beck R, Belin M, Dontchev M, Feder RS, Gal RL, Holland EJ, Kollman C, Mannis MJ, Price F Jr, Stark W, Verdier DD, Cornea Donor Study Investigator Group (Mifflin MD). Effect of donor and recipient factors on corneal graft rejection. Cornea 2012; 31(10),1141-1147
Hsu M, Jorgensen AJ, Moshirfar M, Mifflin MD. Management and outcomes of descemet stripping automated endothelial keratoplasy with intraocular lens exchange, aphakia, and anterior chamber intraocular lens. Cornea 2012
Moshirfar M, Kim G. The role of host endothelial cell proliferation in descemet membrance endothelial transfer. Cornea 2012
Current Eye ResearchShoshani Y Z, Harris A, Shoja MM, Rusia D, Siesky B, Arieli Y, and Wirostko B. Endothelin and its suspected role in the pathogenesis and possible treatment of glaucoma. Curr Eye Res 2012 Jan; 37(1):1-11
Current Opinion in NeurobiologyMarc RE, Anderson JR, Jones BW, Watt CB. Building retinal connectomes. Curr Opin Neurobiol 2012 April; 22:568-574
Current Opinion in Ophthalmology Holt DG, Young J, Stagg B, Ambati BK. Anterior chamber intraocular lens, sutured posterior chamber intraocular lens, or glued intraocular lens: where do we stand? Curr Opin Ophthalmol 2012; 23(1), 62-7
Developmental Dynamics Das G, Clark AM, Levine EM. Cyclin D1 inactiva-tion extends proliferation and alters histogen-esis in the postnatal mouse retina. Develop-mental Dynamics, 2012; 241:941-952
Diabetologia Maile LA, Gollahon K, Wai C, Byfield G, Hartnett ME, Clemmons D. Disruption of the associa-tion of integrin-associated protein (IAP) with tyrosine phosphatase non-receptor type substrate-1 (SHPS)-1 inhibits pathophysiologi-cal changes in retinal endothelial function in a rat model of diabetes. Diabetologia 2012; 55(3), 835-44
EyeNet Magazine Crandall AS. Case 4: fun with zonules (not). EyeNet 2012; (2),48-9.
European Journal of Clinical Nutrition Scarmo S, Henebery K, Peracchio H, Cartmel B, Lin H, Ermakov IV, Gellermann W, Bernstein PS, Duffy VB, Mayne ST. Skin carotenoid status measured by resonance Raman spectroscopy as a biomarker of fruit and vegetable intake in preschool children. Eur J Clin Nutr 2012; 66(5), 555-60
European Journal of Neuroscience Seiler MJ, Jones BW, Aramant RB, Yang PB, Kei-rstead HS, Marc RE. Computational molecular phenotyping of retinal sheet transplants to rats with retinal degeneration. Eur J Neurosci 2012 June; 35(11), 1692-1704
Federation of American Societies for Experimental Biology JournalUehara H, Cho Y, Simonis J, Cahoon J, Archer B, Luo L, Das SK, Singh N, Ambati J, Ambati BK. Dual suppression of hemangiogenesis and lymphangiogenesis by splice-shifting morpholinos targeting vascular endothelial growth factor receptor 2 (KDR). FASEB J 2012
Lin Y, Jones BW, Liu A, Tucker JF, Rapp K, Luo L, Baehr W, Bernstein PS, Watt CB, yang JH, Shaw MV, Marc RE. Retinoid receptors trigger neuritogenesis in retinal degenerations. FASEB J 2012; 26(1), 81-92
Genome MedicineNewman AM, Gallo NB, Hancox LS, Miller NJ, Radeke CM, Maloney MA, Cooper JB, Hageman GS, Anderson DH, Johnson LV, Radeke MJ. Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks. Genome Medicine 2012; 4(2), 16
Human Molecular GeneticsWang L, Zou J, Shen Z, Song E, yang J. Whirlin interacts with espin and modulates its actin-regulatory function: an insight into the mechanism of Usher syndrome type II. Hum Mol Genet 2012; 21(3), 692-710
IEEE Image ProcessingVignesh Jagadeesh, BS Manjunath, BS Anderson, James R, Jones Bryan W, Marc Robert E, Steven Fisher. Parameter estimation in dynamic markov random fields for image sequence analysis. IEEE Image Processing 2012; Online
International Ophthalmology ClinicsShakoor A, Vitale AT. Imaging in the diagnosis and management of multifocal choroiditis and punctate inner choroidopathy. Inter Ophth Clinic, 2012; 52(4), 243-256
Investigative Ophthalmology and Visual SciencesQazi Y, Stagg B, Singh N, Singh S, Zhang X, Luo L, Simonis J, Komeplla UB, Ambati BK. Nanoparticle-mediated delivery of shRNA.VEGF-aplasmids regresses corneal neovascularization. Invest Ophthalmol Vis Sci 2012; 53(6), 2837-44
Cho YK, Uehara H, Young JR, Tyagi P, Kompella UB, Zhang X, Luo L, Sigh N, Archer B, Ambati BK. Flt23k nanoparticles offer additive benefit in graft survival and anti-angiogenic effects when combined with triamcinolone. Invest Ophthalmol Vis Sci 2012; 53(4), 2328-36
Cho YK, Uehara H, Young JR, Archer B, Zhang X, Ambati BK. Vascular endothelial growth factor receptor 1 morpholino decreases angiogenesis in a murine corneal suture model. Invest Ophthalmol Vis Sci 2012; 53(2), 685-92
Bernstein PS, Ahmed F, Liu A, Allman S, Sheng X, Sharifzadeh M, Ermakov I, Gellermann W. Macular pigment imaging in AREDS2 participants: an ancillary study of AREDS2 subjects enrolled at the Moran Eye Center. Invest Ophthalmol Vis Sci 2012; 53(10), 6178-86
Daniels AB, Lee JE, MacConaill LE, Palescandolo E, Van Hummelen P, Adams SM, DeAngelis MM, Hahn WC, Gragoudas ES, Harbour JW, Garraway LA, Kim IK. High throughput mass spectrometry-based mutation profiling of primary uveal melanoma. Invest Ophthalmol Vis Sci 2012 Oct 9; 53(11):6991-6
Zhang T, Baehr W, Fu y. Chemical chaperone TUDCA preserves cone photoreceptors in a mouse model of Leber congenital amaurosis. Invest Ophthalmol Vis Sci 2012; 53(7), 3349-3356
Ross JW, Fernandez de Castro JP, Zhao J, Samuel M, Walters E, Rios C, Bray-Ward P, Jones BW, Marc RE, Wang W, Zhou L, Noel JM, McCall MA, DeMarco PJ, Prather RS, Kaplan HJ. Generation of an inbred miniature pig model of retinitis pigmentosa. Invest Ophthalmol Vis Sci 2012 January; 53(1), 501-507
Japanese Journal of OphthalmologyJones BW, Kondo M, Terasaki H, Lin Y, McCall M, Marc RE. Retinal remodeling. Jpn J Ophthalmol 2012; 56(4), 289-306
Journal of AAOPSBlair MP, Shapiro MJ, Hartnett ME. Fluorescein-anaiography to estimate normal peripheral retinal nonperfusion in children. J AAPOS 2012; 16(3), 234-7
young MP, Heidary G, VanderVeen DK. Relationship between the timing of cataract surgery and develpment of nystagmus in patients with bilateral infantile cataracts. J AAPOS 2012; 16(6), 554-7
Journal of Cataract & Refractive SurgeryMoshirfar M, Kim G. Complications related to the explanation of cosmetic iris implants. J Cataract Refract Surg 2012; 38(10), 1876-7
Slade DS, Hater MA, Cionni RJ, Crandall AS. Ab externo scleral fixation of intraocular lens. J Cataract Refract Surg 2012; 38, 1316-2
McIntyre JS, Werner L, Fuller SR. Kavouissi AC, Hill M, Mamalis N. Assesment of a single-piece hydrophilic acrylic IoL for piggyback sulcus fixation in pseudophakic cadaver eyes. J Cataract Refract Surg 2012 Jan 1; 38, 155-62
Bodnar Z, Clouser S, Mamalis N. Toxic anterior segment syndrome: update on the most common causes. J Cataract Refract Surg 2012; 38,1902-10
Goecks T, Werner L, Mamalis N, Fuller SR, Jensen M, Kavoussi SC, Hill M, olson RJ. Toxicity
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comparison of intraocular azithromycin with and without a bioadhesive delivery system in rabbit eyes. J Cataract Refract Surg 2012; 38(1), 137-145
oberg TJ, Sikder S, Jorgensen AJ, Mifflin MD. Topical-intracameral anesthesia without preoperative mydriatic agents for Descemet-stripping automated endothelial keratoplasty and phacoemulsification cataract surgery with intraocular lens implantation. J Cataract Refract Surg 2012; 38 (3), 384-6
Holt DG, Sikder S, Mifflin MD. Surgical management of traumatic LASIK flap dislocation with macrostriae and epithelial ingrowth 14 years postoperatively. J Cataract Refract Surg 2012; 38(2), 357-61
Moshirfar M, Kim G. May consultation #2. J Cataract Refract Surg 2012; (6), 459-64
DeMill DL, Zaugg BE, Pettey JH, Jensen JD, Jardine GJ, Wong G, olson RJ. objective comparison of 4 nonlongitudinal ultrasound modalities regarding efficiency and chatter. J Cataract Refract Surg 2012; 38(6), 1065-1071
Stringham J, Pettey JH, olson RJ. Evaluation of variables affecting intraoperative aberrometry. J Cataract Refract Surg 2012 Mar; 38(3), 470-4
Ollerton A, Werner L, Fuller SR, Kavoussi SC, McIntyre JS, Mamalis N. Evaluation of a new single-piece 4% water content hydrophobic acrylic intraocular lens in the rabbit model. J Cataract Refract Surg 2012 Oct; 38(10):1827-32
Leishman L, Werner L, Bodnar Z, Ollerton A, Michelson J, Schmutz M, Mamalis N. Prevention of capsular bag opacification with a modified hydrophilic acrylic disk-shaped intraocular lens. J Cataract Refract Surg 2012 Sep; 38(9), 1664-70
Werner L, Michelson J, Ollerton A, Leishman L, Bodnar Z. Anterior segment optical coherence tomography in the assessment of postoperative intraocular lens optic changes. J Cataract Refract Surg 2012 Jun; 38(6), 1077-85
Jaber R, Werner L, Fuller S, Kavoussi SC, McIntyre S, Burrow M, Mamalis N. Comparison of capsulorhexis resistance to tearing with and without trypan blue dye using a mechanized tensile strength model. J Cataract Refract Surg 2012 Mar; 38(3), 507-12
Werner L, Wilbanks G, Ollerton A, Michelson J. Localized calcification of hydrophilic acrylic intraocular lenses in association with intracameral injection of gas. J Cataract Refract Surg 2012 Apr; 38(4), 720-1
Michelson J, Werner L, Ollerton A, Leishman L, Bodnar Z. Light scattering and light transmittance in intraocular lenses explanted because of optic opacification. J Cataract Refract Surg 2012 Aug; 38(8), 1476-85
Sorensen T, Chan CC, Bradley M, Braga-Mele R, olson RJ. Ultrasound-induced corneal incision contracture survey in the United States and Canada J Cataract Refract Surg. 2012 Feb; 38(2):227-33
Journal of Clinical Neuroscience French KF, Hoesch RE, Allred J, Wilder M, Smith AG, Digre KB, La Barge DV 3rd. Repetitive use of intra-arterial verapamil in the treatment of reversible cerebral vasoconstriction syndrome. J Clin Neurosci 2012; 19(1), 174-6
Irak-Dersu I, Thostenson J, Durcan FJ, Hamilton SM, Digre KB. optic disc and visual findings in migraine patient. J Clinical Neuroscience. 2012; 24 September Online
Journal of Comparative Neurology Lauritzen JS, Anderson JR, Jones BW, Watt CB, Mohammed S, Hoang JV, Marc RE. oN cone bipolar cell axonal synapses in the oFF inner plexiform layer of the rabbit retina. J Comp Neurol 2012 Oct 8
Journal of Developmental BiologyKruse-Bend R, Rosenthal J, Quist TS, Veien ES, Fuhrmann S, Dorsky RI, Chien CB. Extraocular ectoderm triggers dorsal retinal fate during optic vesicle evagination in zebrafish. Dev Biol 2012; 371, 57-65
Al Diri I, Vetter ML. PRC2 during vertebrate organogenesis: a complex in transition. Dev Biol 2012; 367:91-99
Journal of GlaucomaHoffman RS, Crandall AS, Crandall DA, Fine IH, Packer M, Sims AC. Minimally invasive external mini-glaucoma shunt implantation without conjunctival dissection. J Glaucoma 2012
Stewart WC, DeMill DL, Wirostko BM, Nelson LA, Stewart JA. Review of the influence of pigment dispersion and exfoliation glaucoma diagnosis on intraocular pressure in clinical trials evaluating primary open-angle glaucoma and ocular hypertension. J Glaucoma 2012 Jan 20
Journal of Neural EngineeringRA Normann, Dowden BR, Frankel MA, Wilder AM, Hiatt SD, Ledbetter NM, Warren DA, Clark GA. Coordinated, multi-joint, fatigue-resistant feline stance produced by Utah slanted electrode arrays in hind limb nerves. J Neural Eng 2012 Apr; 9(2):026019
Journal of Neuro-OphthalmologyDigre KB, Brennan KC. Shedding light on photophobia. J Neuro-ophthalmol 2012; 32(1), 68-81
Shelton JB, Digre KB, Katz BJ, Warner JE. Chiasmal stroke in patient with atrial fibrillation and complete occlusion of right internal carotid artery. J Neuro-ophthalmol 2012
Shelton JB, Digre KB, Katz BJ, Warner JE. Reversible prolonged bilateral inferior altitudinal visual field defects associated with migraine. J Neuro-ophthalmol 2012
Journal of Neuroscience Shushruth, Mangapathy P, Ichida JM, Bressloff PC, Schwabe L, Angelucci A. Strong recurrent networks compute the orientation-tuning of surround modulation in the primate primary visual cortex. J. Neurosci 2012; 32:308-321
Lee D, Chona FV, Ferrell W, Tam B, Jones BW, Marc RE, Moritz O. Dysmorphic photoreceptors in a P23H mutant rhodopsin model of retinitis pigmentosa are metabolically active and capable of regenerating to reverse retinal degeneration. J Neurosci 2012 Feb; 32(6), 2121-2128
Journal of Ophthalmology Moshirfar M, Hsu M, Schulman J, Armenia J, Sikder S, Hartnett ME. The incidence of central serous chorioretinopathy after photorefractive keratectomy and laser in situ keratomileusis. J Ophthalmol 2012; 27-32
Shelton JB, Digre KB, Katz BJ, Warner JE, Quigley EP. Chiasmal stroke in patient with atrial fibrillation and complete occlusion of right internal carotid artery. J Ophthalmol 2012; 32(2),189
Journal of Pediatric Gastroenterology Chan GM, Chan MM, Gellermann W, Ermakov I, Ermakova M, Bhosale P, Bernstein P, Rau C. Resonance raman spectroscopy and the preterm infant carotenoid status. J Pediatr Gastroenterol Nutr 2012
Journal of PhysiologyMolnar T, Barabas P, Birnbaumer L, Punzo C, Kefalov V and Krizaj D. Store-operated channels regulate intracellular calcium in mammalian rods. Journal of Physiology 2012; 590: 3465
Journal of Proteome ResearchLen AC, Powner MB, Zhu L, Hageman GS, Song X, Fruttiger M, Gillies MC. Pilot application of iTRAQ to the retinal disease macular telangiectasia. J Proteome Res 2012; 11(2), 537-53
Journal of Refractive Surgery Mifflin MD, Hatch BB, Sikder S, Kurz CJ, Moshirfar M. Custom vs conventional PRK: a prospective, randomized, contralateral eye comparison of postoperative visual function. J Refract Surg 2012; 28(2), 127-32
Moshirfar M, Christiansen SM, Kim G. Comparison of the ratio of keratometric change to refractive change induced by myopic ablation. J Refract Surg 2012; 28(10), 675-82
Middle Eastern African Journal of Ophthalmology Moshirfar M, Anderson E, Hsu M, Armenia JM, Mifflin MD. Comparing the rate of regression after conductive keratoplasty with or without prior laser-assisted in situ keratomileusis or photorefractive keratectomy. Middle East Afr J Ophthalmol 2012; 19(4),376-81
Molecular Neurodegeneration Lin Y, Jones BW, Liu A, Vazquéz-Chona FR, Lauritzen JS, Ferrell WD, Marc RE. Rapid glutamate receptor 2 trafficking during retinal degeneration. Mol Neurodegener. 2012 Feb; 10;7:7. doi: 10.1186/1750-1326-7-7
Molecular Vision Baas DC, Ho L, Tanck MW, Fritsche LG, Merriam JE, van Het Slot R, Koeleman BP, Gorgels TG, van Duijn CM, Uitterlinden AG, de Jong PT, Hofman A, Ten Brink JB, Vingerling JR, Klaver CC, Dean M, Weber BH, Allikmets R, Hageman GS, Bergen AA. Multicenter cohort association study of SLC2A1 single nucleotide polymorphisms and age-related macular degeneration. Mol Vis 2012; 18, 657-74
Nepal Journal of OphthalmologyThapa R, Poudyal G, Maharjan N, Bernstein PS. Demographics and awareness of diabetic retinopathy among diabetic patients attending the vitreo-retinal service at a tertiary eye care center in Nepal. Nepal J Ophthalmol 2012; 4(7), 10-6
NeurocaseAfra P, Anderson J, Funke M, Johnson M, Matsuo F, Constantino T, Warner JE. Neurophysiological investigation of idiopathic acquired auditory-visual synesthesia. Neurocase 2012; 18(4),323-9
Neuro-Oncology Fisher MJ, Loguidice M, Gutmann DH, Listernick R, Ferner RE, Ullrich NJ, Pakcer RJ, Tabori U, Hoffman Ro, Ardern-Holmes SL, Hummel TR, Hargrave DR, Bouffet E, Charrow J, Bilaniuk LT, Balcer LJ, Liu GT. Visual outcomes in children with neurofibromatosis type 1-associated optic pathway glioma following chemotherapy: a multicenter retrospective analysis. Neuro-Oncol 2012; (2), 1-8
New England Journal of Medicine Hartnett ME, Penn JS. Mechanisms and management of retinopathy of prematurity. N Engl J Med 2012; 367(26), 15-26
Ocular Immunology and In�ammation Morshedi RG, Bettis DI, Moshirfar M, Vitale AT. Bilateral acute iris transillumination following systemic moxifloxacin for respiratory illness: report of two cases and review of the literature. Ocul Immunol Inflamm 2012
Oman Journal of OphthalmologyKhakshoor H, Moghaddam AA, Vejdani AH, Armstrong BK, Moshirfar M. Diplopia as the primary presentation of foodborne botulism. Oman J Ophthalmol 2012; 5(2),109-11
Oncol Rep Yu K, Chen Z, Pan X, Yang Y, Tian S, Zhang J, Ge J, Ambati B, Zhuang J. Tetramethylpyrazine-mediated suppression of C6 gliomas involves inhibition of chemokine receptor CxCR4 expression. Oncol Rep 2012; 28(3), 955-60
Open Ophthalmology Journal Betts BS, oberg TJ, Hsu M, Moshirfar M. Choroidal neovascularization following implantation of verisyse iris-supposed phakic intraocular lens in a pregnant myopic patient. Open Ophthalmol J 2012; (6),6-7
Ophthalmology Mwanza JC, Durbin MK, Budenz DL, Sayyad FE, Change RT, Neelakantan A, Godfrey DG, Carter R, Crandall AS. Glaucoma diagnostic accuracy of ganglion cell-inner plexiform layer thickness: comparison with nerve fiber layer and optic nerve head. Ophthalmology 2012; 119(6),1151-8
Kirk KR, Werner L, Jaber R, Strenk S, Strenk L, Mamalis N. Pathologic assessment of complications with asymmetric or sulcus fixation of square-edged hydrophobic acrylic intraocular lenses. Ophthalmology 2012; 119,907-913
Werner L, Zaugg B, Neuhann T, Burrow M, Tetz M. In-the-bag capsular tension ring and intraocular lens subluxation or dislocation: a series of 23 cases. Ophthalmology 2012 Feb; 119(2):266-71
Ophthalmic Research DeMill DL, Wirostko BM, Nelson LA, Stewart JA, Stewart WC. Average eye versus highest intraocular pressure analyses in glaucoma clinical trials. Ophthalmic Res 2012; 49:49-51
Ophthalmic Surgery, Lasers & Imaging Saffra N, Agarwal S, Enin J, Werner L, Mamalis N. In vitro analysis of Nd:yAG laser damage to hydrophilic intraocular lenses. Ophthalmic Surg Lasers Imaging 2012 Jan-Feb; 43(1):45-9
Pharmaceutics Gooch N, Molokhia SA, Condie R, Burr RM, Archer B, Ambati BK, Wirostko BM. ocular drug delivery for glaucoma management. Pharmaceutics 2012
PLoS Genetics Zou C, Levine EM. Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high-affinity DNA binding. PLoS ONE 2012; 7(3), e33576
PLoS One owen LA, Uehara H, Cahoon J, Huang W, SimonisJ, Ambati BK. Morpholino-mediated increase in soluble Flt-1 expression results in decreased ocular and tumor neovascularization. PLoS ONE 2012; 7(3), e33576
Parmalee NL, Schubert C, Figueroa M, Bird AC, Peto T, Gillies MC, Bernstein PS, Kiryluk K, Terwilliger JD, Allikmets R. Identification of a potential susceptibility locus for macular telangiectasia type 2. PLoS ONE 2012; 7(8), e24268
Njauw CN, Kim I, Piris A, Gabree M, Taylor M, Lane AM, DeAngelis MM, Gragoudas E, Duncan LM, Tsao H. Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families. PLoS One 2012; 7(4):e35295
Igo RP Jr, Kopplin LJ, Joseph P, Truitt B, Fondran J, Bardenstein D, Aldave AJ, Croasdale CR, Price MO, Rosenwasser M, Lass JH, Iyengar SK, FECD Genetics Multi-center Study Group (Mifflin MD). Differing roles for TCF4 and CoL8A2 in central corneal thickness and fuchs endothelial corneal dystrophy. PLoS ONE 2012; 7(10),e46742
Proceedings of the National Academy of Sciences of the United States Dridi S, Hirano Y, Tarallo V, Kim Y, Fowler BJ, Ambati BK, Bogdanovich, Chiodo VA, Hauswirth WW, Kugel JF, Goodrich JA, Ponicsan SL, Hinton DR, Kleinman ME, Baffi JZ, Gelfand BD, Ambati J. ERK1/2 activation is a therapeutic target in age-related macular degeneration. Proc Natl Acad Sci U S A 2012; 109(34),13781-6
Retinal Physician Colucciello M, Vitale AT, Smet M de. Pars Plana vitrectomy for the induction of drug-free remission in uveitis: It’s too soon to tell if PPV is the right way to go in treating uveitis. Retinal Physician, 2012; 9(2):18-22
Vision ResearchZhang H, Constantine R, Frederick JM, Baehr W. The prenyl-binding protein PrBP/δ: a chaperone involved in intracellular trafficking. Vision Res 2012; 75, 19-25
Ronquillo CC, Bernstein PS, Baehr W. Senior-Løken Syndrome: A syndromic form of retinal dystrophy associated with nephronophthisis. Vision Res 2012. 75, 88-97
Constantine R, Zhang H, Gerstner CD, Frederick JM, Baehr W. Uncoordinated(UNC)119: coordinating the trafficking of myristoylated proteins. Vision Res 2012; 75, 26-32
Khanna H, Baehr W. Retina ciliopathies: from genes to mechanisms and treatment. Vision Res 2012; 75, 1
Zou J, Lee A, yang J. The expression of whirlin and Ca(v)1.3alpha(1) is mutually independent in photoreceptors. Vision Res 2012; 75,53 - 5
Books PublishedFoster CS, Vitale A. Diagnosis and Treatment of Uveitis, Second Edition. Jaypee Brothers Medical Publishers, New Delhi, India. 2012
Book Chapters PublishedKrizaj D. Calcium Stores and Photoreceptor Function. In: Calcium Signaling, Advances in Experimental Medicine and Biology vol. 740, Ed. Shahidul Islam, Springer Verlag, Berlin. Invited review. Adv Exp Med Biol 740: 873-889 PMID: 22453974.
Ryskamp DA and Krizaj D. Polymodal Sensory Integration in the Visual System. Proc. IJS, Ljubljana, Slovenia. 2012
Mamalis N, Fuller S. Toxic Anterior Segment Syndrome. In Amar Agarwal, Athlyn Agarwal, Soosan Jacob (Eds.), Phacoemulsification (4th Edition, 38, pp. 137-145). New Dehli, India: Jaypee-Highlights. 2012
Vitale AT, Yang P. How Do I Differentiate Uveitis from Endophthalmitis? In Foster CS, Hinkle D& Opremcak EM (ed.), Curbside Consultation in Uveitis:49 Clinical Questions (Chapter 48). Slack Incorporated, New Jersey. 2012
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R E S E A R C H G R A N T S
Balamurali K Ambati, MD, PhD, MBA
The Role of SFLT in Corneal Avascularity $338,625
National Eye InstituteDuration: 5/1/08–4/30/13
Intraceptor Interference of VEGF Pathways $278,187
National Eye InstituteDuration: 2/1/08–4/30/12
Subconjunctival Glaucoma Gel $35,000
University of Utah Research FoundationDuration: 12/1/11–11/30/12
Retinal Health Analyzer for Novel Therapy and Early Diagnostics for AMD $20,000
carl marshall & mildred almen Reeves FoundationDuration: 12/1/12–8/31/13
Endo-contact Lens for Corneal Protection in Cataract Surgery $35,000
University of Utah Research FoundationDuration: 6/1/12–5/31/13
Endoshield: Making Cataract Surgery Safer and Easier $40,000
Utah Governor’s Office ofeconomic Development Duration: 5/1/12–5/31/13
Pre-mRNA Interference of VEGF. VAMerit Award $650,000
VA Medical Center/Salt Lake City(US Veteran’s Administration)Duration: 10/01/09–9/13/13
Physician-scientist Award $60,000
Research to Prevent Blindness, Inc.Duration: 1/1/09–12/31/12
Intraceptor $1,498,040
NIH National Eye InstituteDuration: 5/1/08–4/30/12
Intraceptor Interference of VEGF inCorneal Angiogenesis. 5R01EY017182-02 $250,000
National Eye InstituteDuration: 4/1/07–3/31/12
Alessandra Angelucci, MD, PhD
V1 to V2 Pathways $372,488
National Institutes of HealthDuration: 8/1/09–7/31/12
Contextual Effects in V1 $120,000
National Science FoundationDuration: 3/1/09–2/29/12
Connectomics-feedback Circuits $28,000
University of Utah Research FoundationDuration: 1/1/12–12/31/12
A Novel Approach for Mapping Single-cell Long-range Connectionsin the Cerebral Cortex $298,916
National Institutes of HealthDuration: 5/1/12–7/31/14
Wolfgang B Baehr, PhD
Core Vision Research Grant (Baehr & Bernstein) $171,493
National Institutes of HealthDuration: 7/1/10–6/30/15
Membrane Protein Trafficking $335,239
National Institutes of HealthDuration: 12/1/08–11/30/13
Photoreceptor Ciliopathies: RP2, KIF17,and NPHP5 $373,750
National Institutes of HealthDuration: 5/1/12–4/30/16
The Role of Nephrocystin-5 in Retinal Degeneration $33,695
National Institutes of HealthDuration: 8/1/12–7/31/14
Study of Retinal Degeneration $57,000
Foundation Fighting BlindnessDuration: 8/1/10–7/31/13
The Function of ANKMY2 $90,500
International Retinal Research FoundationDuration: 10/7/11–11/7/12
Paul S Bernstein, MD, PhD
Biochemistry & Pharmacology of Macular Cartenoids $372,488
National Institutes of HealthDuration: 7/1/07–4/30/12
Macular Disorders $80,000
Macula Vision Research FoundationDuration: 12/16/09–12/15/12
Mactel Macular Carotenoids $147,600
Lowy Medical Research InstituteDuration: 11/1/10–10/31/12
Biochemical Studies in Support of the Next Generation AREDS Supplement for AMD $20,000
carl marshall & mildred almen Reeves FoundationDuration: 12/1/12–8/31/13
Research Grants and Contracts
J o H N A . M o R A N E y E C E N T E R
2012-2013Paul S Bernstein, MD, PhD
Bam114341 $234,887
GlaxosmithklineDuration: 05/01/11–12/31/14
Age-related Eye Disease (AREDS) Study II $168,000
EMMES Corporation/National Eye InstituteDuration: 06/01/06–Present
Biochemistry and Pharmacology of the Macular Cartenoids R01 EY 11600 $1,250,000
National Institutes of HealthDuration: 7/1/07–6/30/12
A Phase II/III Study of Encapsulated HumanNTC-201 Cell Implants Releasing Ciliary Neurotropic Factor (CNTF) for Participants with Retinitis Pigmentosa Using Visual Acuity as the Primary Outcome $114,820
Neurotech USA, Inc.Duration: 9/28/07–Present
NEER-CTEC For Vision Research $302,582
Foundation Fighting BlindnessDuration: 3/1/09–2/28/12
Macular Disorders $240,000
Macular Vision Research FoundationDuration: 8/1/09–12/15/12
Foreseehome Device $66,568
Emmes CorporationDuration: 06/1/10–12/31/12
Vpa Protocol $628,276
National Neurovision Research InstituteDuration: 06/1/10–1/31/13
Macular Pigment Carotenoids $179,500
Lowy Medical Research InstituteDuration: 12/1/10–11/30/12
Bam114341 $234,887
GlaxosmithklineDuration: 5/1/11–12/31/14
Opera $3,109
Emmes CorporationDuration: 10/1/11–9/30/12
MacTel Genetics Study $66,506
Lowy Medical Research Institute, Ltd.Duration: 5/1/89–12/31/12
AREDS 2 $149,081
Emmes CorporationDuration: 1/1/06–12/31/12
Alan S Crandall, MD
Oms302-Ilr-004 $48,270
Omeros CorporationDuration: 4/12/12–6/30/13
Oms302-Ilr-003 $21,467
Omeros CorporationDuration: 9/1/11–12/31/12
Cypass Glaucoma Implant $110,289
Transcend Medical, Inc.Duration: 1/1/11–12/31/14
Margaret DeAngelis, PhD
Identifying Underlying Mechanisms of Age-related Macular Degeneration $250,000
Edward N & Della L Thome MemorialDuration: 7/1/10–12/14/12
Identifying Underlying Mechanisms of Age-related Macular Degeneration for the Development of Appropriate Preventive and Therapeutic Interventions $681,816
Edward N & Della L Thome Memorial FoundationDuration: 12/15/09–12/14/12
Research to Understand the Genetic Epidemiology of Blinding Diseases of the Posterior Eye among Federally Recognized Native Americans $963,100
ALSAM FoundationDuration: 3/16/12–12/31/13
To Continue to Build a Repository of HumanEyes from the Utah Lions Eye Bank for Tissue Including the Isolation of Human Choroidal Endothelial Cells for Studies of Age-related Macular Degeneration for the Purpose of Gene Expression Assays and Functional Studies by the DeAngelis and Hartnett Laboratories $20,000
Principal Investigators: Margaret DeAngelis, Mary Elizabeth Hartnettcarl marshall reeves & mildred almen reeves Foundation, Inc.Duration: 12/1/12–8/31/13
Genetic Study of the Utah and Iowa Cohorts for Age-related Macular Degeneration $7,000
Educational Resource Development CouncilDuration: 5/1/11–5/31/12
Genetic Epidemiology Of AMD $94,310
Brigham and Women’s HospitalDuration: 9/1/10–8/31/12
Sibling Study of Age-related MacularDegeneration R01 EY-014458 $1,000,000
National Institutes of HealthDuration: 1/1/09–12/31/12
Kathleen B Digre, MD
Utah Women’s Health Information Network $500,000
Utah Department of Health Duration: 9/1/07–Present
Pairing Local Libraries with Local Health Centers $25,000
Department of Health and Human Services Duration: 1/1/08– Present
Gender-based Research na
Office on Women’s Health, Department of Health and Human Services Duration: 9/1/11–8/31/16
Coalition Healthier Community $465,701
National Cancer InstituteDuration: 9/1/11–08/31/16
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Kathleen B Digre, PhD
Women’s Health Conference $1,811
DHHS Office on Women’s Health Duration: 12/2/11–9/14/12
Heart Campaign for Women $10,000
DHHS Office on Women’s Health Duration: 12/12/11–9/14/12
National Women’s Health Week 2012 $2,500
DHHS Office on Women’s Health Duration: 1/1/12–6/30/12
Nordic Iihtt $147,365
St. Lukes-Roosevelt Hospital Center Duration: 10/1/09–1/31/12
yingbin Fu, PhD
Cone Opsins in Photoreceptor Degeneration $373,541
National Institutes of Health Duration: 9/30/12–8/31/17
RPB Career Development Award $200,000
Research to Prevent Blindness Duration: 7/1/08–6/30/12
Strategies-Leber Congenital Amaurosis $240,000
E Matilda Ziegler Foundation Duration: 7/1/11–6/30/14
Leber Congenital Amaurosis $40,000
Knights Templar Eye Foundation Duration: 7/1/11–6/30/12
Development of Effective Therapies for Leber Congenital Amaurosis $60,000
Knights Templar Eye Foundation Duration: 7/1/12–6/30/13
A New Treatment Strategy for Age-related Macular Degeneration $20,000
Carl Marshall & Mildred Almen Reeves Foundation Duration: 12/1/2012– 8/31/2013
Sabine Fuhrmann, PhD
Mechanisms Controlling RPE Development $376,250
National Institutes of Health Duration: 1/1/10–12/31/13
Jason Goldsmith, MD
Communication about Glaucoma $54,551
University of North Carolina at Chapel Hill Duration: 3/1/11–4/30/13
Communication about Glaucoma and Patient Outcomes $91,426
National Institutes of Health Duration: 2/1/11–Present
Gregory S Hageman, PhD
DEC Complement MOD Therapy $2,986,452
National Institutes of Health Duration: 9/1/09–7/31/12
Genetic Susceptibility to Age-related Macular Degeneration $55,963
Columbia University Duration: 9/1/10–8/31/13
Hyperspectral Imaging of the Normal and Age-related Macular Degeneration $37,243
New York University Duration: 4/1/11–3/31/13
Research to Prevent Blindness Senior Scientific Investigator Award $150,000
Research to Prevent Blindness, Inc. Duration: 1/1/12–12/31/12
Improved Characterization of High-risk Phenotypes in Early AMD, Employing Novel Imaging and Functional Modalities $400,000
Macular Degeneration Foundation of Australia Duration: 10/4/11–10/4/14
Investigations of AMD in Africa $25,000
American Macular Degeneration Foundation Duration: 7/28/11–07/28/12
Alcon Recognition Award $200,000
Alcon Laboratories, Inc. Duration: 1/1/10–12/31/12
Development of Complement Modulating Therapeutics for Age-related Macular Degeneration: 1-R24-EY017404 $12,837,275
National Institutes of Health Duration: 8/1/06–7/31/12
Mary Elizabeth Hartnett, MD
Mechanisms of Angiogenesis in ROP $438,909
National Institutes of Health Duration: 7/1/10–6/30/14
Endothelial Transmigration in Neovascular Age-related Macular Degeneration $373,7505
National Institutes of Health Duration: 4/1/12–3/31/17
Diabetic Retinopathy Clinical Research Network NA
National Institutes of Health Duration: 1/1/11–Present
3R01 EY017011 03S1- Endothelial Transmigration in Neovascular Age-related Macular Degeneration, Instrument Supplement $500,000
National Institutes of Health Duration: 1/1/09–11/1/12
Endothelial Transmigration in Neovascular Age-related Macular Degeneration 3R01 EY01 $373,750
National Eye Institute Duration: 1/1/07–2/29/17
Studies on Angiogenic Mechanisms and Saftey Regarding Erythroprotein in Retinopathy of Prematurity: Seeking a Safe Treatment $90,000
March of Dimes Utah Chapter Duration: 2012–2015
Bryan W Jones, PhD
Normal Aging vs. Late Stage AMD Phenotypes $250,000
Edward N & Della L Thome Memorial Duration: 12/15/09–9/14/13
Retinal Circuits $827,185
Principal Investigators: Bryan W Jones, Robert E Marc
National Institutes of Health Duration: 12/1/11–11/30/16
Retinal Remodeling $440,990
Principal Investigators: Bryan W Jones, Robert E Marc
National Institutes of Health Duration: 12/1/03–3/31/16
Bradley J Katz, MD, PhD
Blast Ocular Injury $718,099
Principal Investigators: Brittany Coats, Yingbin Fu, Jason A Goldsmith, Bradley J Katz Kenneth L Monson
Army Medical Research Acquisition Activity Duration: 9/1/12–8/31/16
Quark 007 $93,635
Quark Pharmaceuticals, Inc. Duration: 9/1/12–8/31/16
David Krizaj, PhD
Regulation of Neurotransmission in the Retina $321,829
National Eye Institute Duration: 9/1/07–8/31/13
Core Vision Research Grant $85,254
National Institutes of Health Duration: 7/1/10–6/30/15
Role of Mechanosensation in the Retina $249,652
Nation Institutes of Health Duration: 12/1/12–11/30/16
Characterization of Molecular Mechanisms of Ocular Blast Trauma $269,406
Army Medical Research Acquisition Activity Duration: 8/15/12–8/14/2016
Retinal Inflammation and Degeneration are Modulated by TRPC Channels in Retinal Muller Glia $40,000
Knights Templar Eye Foundation Duration: 7/1/11–6/30/12
Pressure Transduction and Neuroprotection in Glaucoma $18,500
University of Utah Research Foundation Duration: 7/1/12–6/30/13
Novel TRPV4 Antagonist Prodrug for Treatment of Glaucoma $10,000
University of Utah Technology Commercialization Duration: 2012-2013
The Role of Very Long Chain Polyunsaturated Acids (VLC-PUFAs) in Dominant Stargardt Disease (STGD3) and Dry Age-related Macular Degeneration, TA-NMT-0810-0502-UUT $195,000
Principle Investigators: David Krizaj, Paul S Bernstein Foundation Fighting Blindness
Duration: 8/1/10–7/31/13
Edward M Levine, PhD
CCX10 Embryonic Retinal Cells $344,178
National Institutes of Health Duration: 12/1/08–11/30/12
Core Vision Research Grant $112,354
National Institutes of Health Duration: 7/1/10–6/30/15
Development & Evaluation of Mouse Models for Treating Retinal-related Pathologies $28,000
University of Utah Research Foundation Duration: 7/1/11–6/30/12
Nick Mamalis, MD
Power Adjustment and Biocompatibility, Amend #21 NA
Principal Investigators: Nick Mamalis, Liliana Werner
Calhoun Vision Inc. Duration: 5/5/07–4/30/12
Assessment of Capsular Bag Opacification after Implantation of Piggy Back IOL’s and a Dual-optic IOL NA
Principal Investigators: Nick Mamalis, Liliana Werner
Visiogen Inc. Duration: 1/1/05–Present
Evaluation of Removal of Lens Epithelial Cells in a Pig Eye NA
Alcon Research Ltd. Duration: 1/1/05–Present
AquaLase for Removal of Residual Lens Epithelial Cells During Cataract Extraction NA
Alcon Research Ltd. Duration: 3/1/05–Present
Gross and Histopathologic Evaluation of Explanted Rabbit Eyes that had been Implanted with a New Intraocular Lens NA
Principal Investigators: Nick Mamalis, Liliana Werner
Advanced Medical Optics Duration: 3/1/05–Present
Evaluation of EpiLoop to Remove Lens Epithelial Cells in Human Cadaver Eyes NA
Principal Investigators: Nick Mamalis, Liliana Werner
Phaco Treat Duration: 2/2/06–Present
Evaluation of the Power Adjustment and Biocompatibility of the Light Adjustable Lens in a Rabbit Model NA
Principal Investigators: Nick Mamalis, Liliana Werner
Calhoun Vision, Inc. Duration: 3/1/06–Present
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Mark D Mifflin, MD
CPTS $51,800
Jaeb Center for Health Research Duration: 7/1/12–6/30/17
CPTS $109,350
Jaeb Center for Health Research Duration: 03/1/12–6/30/17
Evaluation of Topical Antibiotics/Risk of Endophthalmitis with Intravitreal Injection $20,000
Allergan, Inc. Duration: 1/1/09–Present
Cornea Donor Study: National Multicenter Investigation to Study the Effect of Age on Cornea Transplant Outcome $27,134
National Eye Institute Duration: 8/1/99–7/31/13
Robert E Marc, PhD
Structural Neurochemistry of Retinal Circuits $614,251
National Eye Institute Duration: 12/1/11–11/30/16
Retinal Remodeling $627,106
National Eye Institute Duration: 4/1/12–3/31/13
Core Vision Research Grant $166,840
National Eye Institute Duration: 7/1/10–6/30/15
Core Vision Research Grant (Main) $41,974
National Eye Institute Duration: 7/1/10–6/30/15
Core Vision Research Grant (Supplement) $300,000
National Eye Institute Duration: 7/1/12–6/30/13
Challenges in Imaging (ARRA) UCSB Subcontract $89,932
National Science Foundation Duration: 10/1/09–9/30/13
Retinoic Acid Plasticity $35,000
International Retinal Research Foundation Duration: 7/1/11–6/30/12
Normal Aging vs Late-stage AMD $691,825
Principal Investigators: Gregory S Hageman, Bryan W Jones, Robert E Marc
Edward N & Della L Thome Memorial Foundation Duration: 12/15/09–12/14/12
Retinal Remodeling $874,688
National Eye Institute Duration: 12/01/08–11/30/13
Retinal Circuits $1,569,456
National Institutes of Health Duration: 3/1/93–12/31/12
Majid Moshirfar, MD
ACOS Kxl-001 NA
Avedro, Inc. Duration: 9/1/12–6/30/13
IMT $71,090
VisionCare Ophthalmic Technologies, Inc. Duration: 12/2/11–12/31/16
Richard A Normann, PhD
Control of Efferent and Afferent Peripheral Nerve Activity with Intrafascicular Microstimulation $198,458
National Science Foundation Duration: 9/1/11–8/31/13
Randall J olson, MD
A Prospective Multi-centered Study of AcrySof Glistenings $25,000
Advanced Medical Optics, Inc. Duration: 6/1/08–Present
Assessing Post-occlusion Surge in Vacuum Flow Systems $10,000
Bausch & Lomb Duration: 05/1/08–Present
Visualizing MRSA Response to BAK +/- Gatifloxacin $8,000
Allergan, Inc. Duration: 5/1/08–Present
An Eyebank Comparison of Corneal Endothelial Damage with Dispersive OVDs $6,000
Advanced Medical Optics, Inc. Duration: 4/1/08–Present
Recovery of Bacteria from Intraocular Injection in Cadaver Eyes $25,000
Allergan, Inc. Duration: 8/1/07–Present
Differentiating the Effect of BAK and 4th Generation Fluoroquinolones against MRSA $12,000
Allergan, Inc. Duration: 4/1/07–Present
Michael P Teske, MD
The Natural History of Geographic Atrophy Progression (GAP) Study $75,900
Alcon Research Ltd Duration: 1/31/08–Present
GATE $312,860
Alcon Research Ltd Duration: 4/15/09–6/30/12
A Randomized, Double-masked, Active Controlled Phase III Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal VEGF Trap in Subjects with Neovascular Age-related Macular Degeneration Clinical Evaluation of Anti-angiogenesis in the Retina–Intravitreal Trial 3 (CLEAR-IT 3) NA
Regeneron Pharmaceuticals, Inc. Duration: 4/1/07–Present
A Phase 2, Randomized, Double-masked, Placebo-controlled, Dose-ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injections of Sirolimus in Patients with Diabetic Macular Edema Secondary to Diabetic Retinopathy NA
Sub investigator Macusight, Inc. Duration: 10/14/08–Present
Northern California Section of the Collaborative Ocular Melanoma Study NA
National Eye Institute Duration: 1/1/87–Present
Ning Tian, PhD
Development of Synaptic Pathways $374,375 in Retina
National Institutes of Health Duration: 4/1/11–3/31/16
Development of Synaptic Pathways in Retina (Supplement) $263,900
National Institutes of Health Duration: 4/1/12–3/31/13
Monica Vetter, PhD
1 R21 EY019390 Retina-derived Signals Regulating Development of the Vitreous Hyaloid Vasculature $413,771
National Institutes of Health, NEI Duration: 7/1/09–6/30/12
Catalyst for a Cure $1,101,250
Glaucoma Research Foundation Duration: 1/1/10–12/31/12
2 R01 EY012274 Regulation of Retinal Neurogenesis by bHLH Factors $2,740,163
National Institutes of Health Duration: 7/1/08–6/30/13
1 R01 EY020878 Role of Microglia in Experimental Glaucoma $984,465
National Institutes of Health Duration: 7/1/10–6/30/15
Albert T Vitale, MD
A Phase 2, Randomized, Double-masked, Controlled Trial to Establish the Safety and Efficacy of Intravitreous Injections of E10030 (Anti-PDGF Pegylated Aptamer) Given in Combination with Lucentis in Subjects with Neovascular Age-related Macular Degeneration NA
Sub-Investigator Ophthotech Corporation Duration: 8/17/10–Present
The Safety and Efficacy of AL-8309B Ophthalmic Solution for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration NA
Sub-Investigator Alcon Research Ltd Duration: 8/18/09–Present
Phase II/III Study of Encapsulated Human NTC-201 Cell Implants Releasing Ciliary Neurotrophic Factor (CNTF) for Participants with Retinitis Pigmentosa Using Visual Acuity as Primary Outcome NA
Neurotech USA, Inc. Duration: 4/1/07–Present
Multicenter Uveitis Steroid Treatment (MUST) Trial $281,000
Johns Hopkins University Neuro-education Initiative Duration: 12/1/05–Present
Genetic Epidemiology $963,100
Principal Investigators: Paul S Bernstein, Margaret DeAngelis, Mary Elizabeth Hartnett, Albert T Vitale
ALSAM Foundation Duration: 3/16/12–12/31/13
A Phase 2, Multi-center, Randomized, Double-masked, Placebo-controlled, Parallel-group Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of GSK933776 in Adult Patients with Geographic Atrophy Secondary to Age-related Macular Degeneration NA
Sub-Investigator Glaxosmithkline Duration: 9/21/11–Present
MUST Follow-up Study $7,731
Johns Hopkins University Duration: 5/1/12–4/30/13
C-10-034 Durazol Uveitis $32,733
Alcon Research Ltd Duration: 12/1/10–12/31/12
Adalimumab M10-880 $93,537
Abbott Laboratories Duration: 7/1/10–12/31/12
Adalimumab M10-877 $95,771
Abbott Laboratories Duration: 7/1/10–12/31/12
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Albert T Vitale, MD
Adalimumab M11-327 $63,014
Abbott LaboratoriesDuration: 7/1/10–12/31/12
Double-mass, Placebo-controlled, Multi-centered, Dose-ranging Study to Assess the Efficacy and Safety of LX211 as Therapy Clinically Quiescent Sight-threatening, Non-infectious Uveitis na
Lux Biosciences, Inc.Duration: 4/1/07–Present
Comparison of AMD Treatment Trial (CATT)–Lucentis–Avastin Trial na
Emmes Corporation/National Eye InstituteDuration: 4/1/07–Present
A Phase III Study of the Efficacy and Safety of RhufabV2 (Ranibizumab) In Subjects with Minimally Classic or Occult Subfoveal Neovascular Age-related Macular Degeneration (MARINA) na
Sub-Investigator Unmasked Treating Physician Genentech Inc.Duration: 3/1/03–Present
Phase II Clinical Trial: A Multicenter Randomized Double-masked Controlled Study to Evaluate the Safety and Efficacy of an Intravitreal Fluocinolone Acetonide (0.5 or 2 mg) Implant in Patients with Noninfectious Uveitis Affecting the Posterior Segment of the Eye, American Study na
Bausch & LombDuration: 1/1/03–Present
A Multicenter, Randomized Controlled Study to Evaluate the Safety and Efficacy of an Intravitreal Flucinolone Acetonide (0.5mg)Implant Compared to Standard Therapy in Patients with Non-infectious Uveitis Affecting the Posterior Segment of the Eye na
Co-InvestigatorBausch & LombDuration: 4/1/02–Present
Judith E A Warner, MD
A Multicenter, Double-blind, Randomized, Placebo-controlled Study of Weight- reduction and/or Low-sodium Diet Plus Acetazolamidevs Diet plus Placebo in Subjects with Idiopathic Intracranial Hypertension with Mild Visual Loss Neuro- Ophthalmology Research Disease $80,500
Sub Investigator Investigator ConsortiumDuration: 11/30/09–11/30/15
Liliana Werner, MD, PhD
Evaluation of a New IOL $8,529
Principal Investigators: Nick Mamalis, Liliana Werner
PhysIOLDuration: 11/1/12–4/30/13
Evaluation of a New IOL $66,537
Principal Investigators: Nick Mamalis, Liliana Werner
Abbott Medical OpticsDuration: 2/10/12–1/31/13
New Intraocular Lens Material $20,374
Principal Investigators: Nick Mamalis, Liliana Werner
Innovia LLCDuration: 9/19/11–7/31/12Duration: 9/19/11–7/31/12Duration: 9/19/11–
Evaluation of a New IOL $10,986
Principal Investigators: Nick Mamalis, Liliana Werner
Advanced Vision Science, Inc.Duration: 10/1/10–9/30/13
Evaluation of a New IOL $43,323
Principal Investigators: Nick Mamalis, Liliana Werner
Anew Optics, Inc.Duration: 5/1/10–4/30/13
Silicone Oil in the Eye $201,211
Principal Investigators: Nick Mamalis, Liliana Werner
PowerVision, Inc.Duration: 3/30/09–Present
Evaluation of a Dual-optic IOL $48,650
Principal Investigators: Nick Mamalis, Liliana Werner
Visiogen, Inc.Duration: 1/15/09–12/15/12
Jun yang, PhD
Formation and New Components of the Usher 2 Placebo-controlled study of Weight-reduction and/or Low-sodium Diet Plus Acetazolamide vs Diet plus Placebo in Subjects with Idiopathic Intracranial Hypertension with Mild Visual Loss Neuro-ophthalmology Research Disease $336,937
National Institutes of HealthDuration: 4/1/11–3/31/16
Formation and Function(s) of the Usher 2 Protein Complex in Photorecptors $80,000
E Matilda Ziegler FoundationDuration: 1/1/11–12/31/13
Gene Therapy for Retinitis Pigmentosain Usher Syndrome Type 2 $50,000
Foundation Fighting BlindnessDuration: 8/1/10–7/31/13
P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E
N AT I o N A L A N D I N T E R N AT I o N A L P R E S E N TAT I o N S
Alessandra Angelucci, MD, PhD Invited Speaker Seminar, Circuits for Spatial Salt Lake City, UT 2002–presentIntegration of Information in the Primate Visual Cerebral Cortex. Math Biology Seminar Series, Department of Mathematics
Invited Speaker Seminar, Rewiring the Brain: Role of England 1998–presentAfferents and Targets in the Generation of Specific and Patterned Connections. Departmental Lecture, University Laboratory of Physiology, Oxford University
Honorary Lectureship, Department of Optometry Manchester, England 2001–presentand Neuroscience, UMIST
Seminar, The Spatial Logic of Intra-areal and Inter- Chicago, IL 1999–presentareal Connections within and between Areas V1, V2, V3, and V5/MT of the Macaque Visual Cortex. Computational Neuroscience Seminar Series, Department of Mathematics, University of Chicago
Invited Speaker Seminar, Rewiring the Brain: Role of Pisa, Italy 1998–presentAfferents and Targets in the Generation of Specific and Patterned Connections. Department of Physiology, Consiglio Nazionale delle Ricerche
Wolfgang B Baehr, PhD Membrane Protein Transport in Photoreceptors. Salt Lake City, UT 2012Department of Biochemistry, University of Utah
Organizer of 14th Vision Research Conference Ft. Lauderdale, FL 2012Retina Ciliopathies: From Genes to Mechanisms and treatment
The Function of PDE6D and UNC119 in Photoreceptors Berlin, Germany 2012
Membrane Protein Transport in Photoreceptors. Nashville, TN 2012Vanderbuilt
Membrane Protein Transport in Photoreceptors. Muenchen, Germany 2012MPI for Biochemistry
Paul S Bernstein, MD, PhD Invited Speaker and Moderator, International Symposium Rome, Italy 2010–presenton Ocular Pharmacology and Therapeutics
Invited Speaker and Panelist, Hohenheim Stuttgart, Germany 2008–presentconsensus conference
Invited Speaker, to Educate Russian Ophthalmologists Saint Petersburg 2010–presenton the Value of Nutritional Supplements for Age- and Moscow, Russia related Macular Degeneration
Invited Speaker, Royal Ophthalmological Society, Elizabeth Nottingham, England 2010–presentThomas Age-related Macular Degeneration Symposium
Invited Speaker, Retina Sub-specialty Day, San Francisco, CA 2012american academy of ophthalmology
Invited Lecturer, Ophthalmic Photographers Society San Francisco, CA 2012
Invited Speaker, Bascom Palmer Eye Institute Miami, FL 2009–present
Invited Speaker, Florida International University Miami, FL 2010–present
This is a partial list of Moran National and International Presentations
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P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E
N AT I o N A L A N D I N T E R N AT I o N A L P R E S E N TAT I o N S
Invited Speaker, American Optometric Association Orlando, FL 2010–present
Invited Lecturer, Ophthalmic Photographers Society Chicago, IL 2011–present
Alan S Crandall, MD Management of Cataract in Challenging Cases. Milan, Italy 2012Malpositioned Lenses: Techniques for Surgical Management. Finer Points in IOL Fixation: New Techniques, New Instrumentation. Management of Co-existing Cataract and Glaucoma: Surgical Challenges. Non-penetrating Glaucoma Surgery and Canaloplasty for New Glaucoma Surgeons. overview of Suprachoroidal Devices. The Surgical Management of Lens Exchange and the Malpositioned IOL. The XXX Congress of the European Society of Cataract & Refractive Surgeons
New Surgical Procedures. Managing Late Subluxation. Santiago, Chile 2012Pseudoexfoliation (Including Use of Capsular Devices). ltrachopper and managing Hard cataracts. managing Combined Glaucoma and Cataract (Trabeculectomy, Express Shunts and Canaloplasty). Express Shunt GlaucomaFiltration Lab. Seventh International Ophthalmology Symposium, University of Chile
Surgical Management of Subluxated Crystalline and Chicago, IL 2012Intraocular Lenses. Management of Difficult Cataracts and Challenging Situations. Finer Points in IOL Fixation: New Techniques, New Instrumentation. Toxic Anterior Segment Syndrome Following Cataract Surgery. Tackling Weak Zonules and Using Capsular Tension Devices. Fixing the Iris: Strategies and Surgical Techniques. Coexisting Cataract and Glaucoma: Tips for the Uneasy Relationship. International Prechop Symposium. Intraocular Lens Exchange and Repositioning Techniques. Risk Factors of Cataract Surgery in PXF. 2-H Intraocular Surgery: Challenging Cases. American Society of Cataract and Refractive Surgery
IOL Exchange. Spotlight on Cataracts: Clinical Decision- Chicago, IL 2012making With Cataract Complications. Advanced Refractive Cataract Surgery and Anterior Segment Reconstruction. Schlemm canal Surgery. the Surgical management of the Malpositioned IOL. Cataract Surgery in the Setting of Ocular Comorbidities and High-risk Features for Intraoperative and Postoperative Complications. One-stop Chop Squad. American Academy of Ophthalmology
Clinical Decisions in the Management of Complications New York, NY 2012of Cataract and IOL Surgery. Arbisser LB, Crandall AS, Hoffer J, Rowen S, Tabin GC, Gills JP, Michelson MA,Nichamin LD, et al. American Academy of Ophthalmology
Invited Speaker, The Role of Adjunctive Testing in Orlando, FL 2012Monitoring Glaucoma. Nuclear Disassembly Technique Including Femtosecond Laser and Nucleus Chopper. Glaucoma Surgery: New Variations and Techniques. Advanced Uses of Capsule Support System Introperatively. Masters in Ophthalmology 2012
Merging Complex Anterior Segment Surgery and Glaucoma: New York, NY 2012Why the Glaucoma Specialist Should Be the Best Surgeon in the Group. american Glaucoma Society 22nd Annual Meeting
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Moderator, New Horizons in Glaucoma Devices. San Francisco, CA 2012–presentGlaucoma 360 - New Horizons Forum
Complex Cataract Cases and Management of Patients Philadelphia, PA 2012–presentwith Subluxed IOLs. Advanced Anterior SegmentUpdate, Wills Eye Institute
Staged Procedures, Surgery. World Ophthalmology Abu Dhabi, United Arab 2012Congress. The XXX111 International Congress Emiratesof ophthalmology
Malpositioned Lenses - Techniques of Surgical Vienna, Austria 2012Management. Course: IC-14 Management of Co-existingCataract and Glaucoma: Surgical Challenges. The Future of Cataract Surgery: Experience and Results. European Society of Cataract and Refractive Surgery
The ABCs of CTRs. Hard Lenses with Loose Zonules Playa del Carmen, 2012in PXE Case Presentation. Winter Update 2010, American MexicoSociety of Cataract and Refractive Surgery
Donnell J Creel, PhD Invited Speaker, Visually Evoked Potentials. International Kathmandu, Nepal 2012Retina and Glaucoma Conference. Tilganga Institute of ophthalmology
Invited Speaker, Visually Evoked Potentials. Chengdu, China 2012Electroretinograms. West China Hospital
Margaret DeAngelis, PhD Genomic Convergent Approach Provides Evidence Boston, MA 2012for a Role of CVD and Lipids in Age-related Macular Degeneration. The AMD Symposium, Harvard Medical School, Schepens Eye Institute
The Genetics of Age-related Macular Degeneration: Boston, MA 2003–presentAn Overview. The AMD Symposium, Massachusetts Eye & Ear Infirmary
Curing Age-related Macular Degeneration in our Lifetime. Salt Lake City, UT 2012Foundation Fighting Blindness Conference.
Genomic Convergent Approach to Characterizing Belfast, Ireland 2012Pathways/Mechanisms Underlying Age-related Macular Degeneration. Ninth Alumni and Research Day Meeting, Queen’s University
Nuclear Receptors as Druggable Targets for Age-related Berlin, Germany 2012Macular Degeneration. International Society for eye research
Kathleen B Digre, MD Idiopathic Intracranial Hypertension: Current Concepts. College Park, MD 2012University of maryland
Caring for Two: Neuro-ophthalmic Disorders in Dallas, TX 2012Pregnancy. The Carol Zimmerman Lecture, University of texas Southwestern texas Southwestern t
Photophobia in Blepharospasm. Dystonia Chicago, IL 2012Coalition Meeting
Episodic to Chronic Migraine and Back Again. Scottsdale, AZ 2012Digre KB, Schwedt TJ. American Headache Society
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Oral Contraceptives and Migraine. American Scottsdale, AZ 2012Headache Society
Common Important Neuro-ophthalmoscopic Findings. New Orleans, LA 2012american academy of neurology
Neuro-ophthalmology. All-day Course, American New Orleans, LA 2012academy of neurology.
Moderator: Treatment. Digre KB, Dodick DW, Scottsdale, AZ 2012Silverstein SD. American Headache Society, Scottsdale Headache Symposium
Gregory S Hageman, PhD Invited Speaker, Biology, Genetics, and Pathways Beijing, China 2012Associated with Age-related Macular Degeneration: a new era. challenge in amD Study
Invited Speaker and Award Recipient, The Pathogenesis New York City, NY 2012Genetics, Diagnosis, and Treatment of Age-related Macular Degeneration: Entering a New Era. Lighthouse International Pisart Vision Award
Keynote Lecture, Toward a Refined Understanding of the Boston, MA 2012Genetics, Biology, and Treatment of Age-related Macular Degeneration. Distinguished Lecture, Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary
Keynote Speaker, Toward a Refined Understanding Omaha, NE 2012of Age-related Macular Degeneration: A New Era. Gifford Lecturer, Gifford-Truhlsen Residents and Alumni Day, University of Nebraska Medical Center
Invited Speaker, Drusen-Harbingers of Age-related Paris, France 2012Macular Degeneration-associated Pathways and Genes.Macula of Paris
Invited Speaker, The Genetics of Non-exudative New York, NY 2012Age-related Macular Degeneration. Macula 2012, Atlantic Coast Retina Club
Invited Speaker, Diagnostics & Therapeutics for Newport Beach, CA 2012Age-related Macular Degeneration: A New Era. Fifth Annual FFB & Gavin Herbert Eye Institute Ophthalmic Innovations Symposium
Moderator, Invited Speaker. Genotype Correlation-Biology- Newport Beach, CA 2012Phenotype. Clinical-pathological Correlation in Patients with a History of Reticular Pseudodrusen. Arnold and Mabel Beckman Initiative for Macular Research
Invited Speaker, Toward a Refined Understanding Chicago, IL 2012of the Biology and Genetics of Age-related Macular Degeneration: Therapeutic & Diagnostic Implications. Eleventh Macular Vision Research Foundation Conference
Invited Speaker, An Integrated Hypothesis of the San Francisco, CA 2012Development and Progression of Age-related Macular Degeneration Based upon Available Genetic and Biological Data. Sixty-second Annual Meeting of the American Society of Human Genetics
Invited Speaker, Hope in Sight, John Moran Eye Center Sun Valley, ID 2012
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Invited Speaker, Toward the Development of Diagnostcs Seoul, South Korea 2012and Therapeutics Targeting Age-related Macular Degeneration and Its Co-segregating Diseases: A New Era. Fifteenth Samsung Macula Symposium, Samsung Medical Center, Sungkyunkwan University School of medicine
Invited Speaker, Toward a Refined Understanding Washington, DC 2012of the Genetics and Biology of Age-related Macular Degeneration. National Eye Institute
Invited Speaker, A New Era: Diagnostics and Therapeutics - Washington, DC 2012Targeting Age-related Macular Degeneration and Its Co-segregating Diseases. Alliance for Eye and Vision Research’s Decade of Vision, 2010-2020 Initiative: a Congressional Briefing, House Rayburn, United States congress
Invited Speaker, Royal Victoria Hospital Belfast, Northern Ireland 2012
Invited Speaker, Unique Angiographic Characteristics Melbourne, Australia 2012Associated with Reticular Psuedodrusen. Fluorescein Conference, Centre for Eye Research Australia
Invited Speaker, Concepts Relating to the Biology of Irvine, CA 2012Age-related Macular Degeneration. Beckman Initiative for Macular Research
Mary Elizabeth Hartnett, MD Personal and Historical Insights into the Henrietta Ft. Lauderdale, FL 2012Lacks Story. The Small GTPase Rap1 Regulates Intracellular ROS Generation in RPE. Wang H, Wittchen E, Hartnett ME. The Association for Research in Vision and Ophthalmology
Retina Lecture: Vascular and Choroidal Disease Salt Lake City, UT 2012(non-diabetic) II. Diabetic Retinopathy. Retinopathy of Prematurity. Considerations Regarding Anti-VEGF Treatments in Severe Retinopathy of Prematurity. John A. Moran Eye Center, University of Utah
Mechanisms involved in Neovascular Age-related Augusta, GA 2012Macular Degeneration. Vision Discovery Institute Distinguished Seminar Series
Delayed Retinal Angiogenesis by VEGF-mediated San Francisco, CA 2012Downregulation of Erythropoltin. PediatricRetinal Vascular Meeting
The Small GTPase Rap1 Regulates Intracellular ROS Ft. Lauderdale, FL 2012Generation in RPE. The Association for Research in Vision and ophthalmology
Invited Speaker, Evidence for use of Avastin in ROP. Salt Lake City, UT 2012Neonatal/Perinatal Conference, University of Utah, Primary Childrens Medical Center
Robert o Hoffman, MD Visiting Professor Lecture, Retinoblastoma. Rapid City, SD 2012Black Hills Regional Eye Institute
Bryan W Jones, PhD Clinical Faculty Day, University of Utah Ophthalmology Salt Lake City, UT 2012
Invited Speaker, Neural Retina. International Berlin, Germany 2012Society for eye research
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Moderator: International Society for Eye Research, Berlin, Germany 2012Retinal Remodeling Session XX Biennial Meeting
Bradley J Katz, MD, PhD Presentation: Treatment of Subjects with Giant Cell San Antonio, TX 2012Arteritis with Antibiotics. A Murine Model of Giant Cell Arteritis: Infection with a Burkholderia Pseudomallei-like Strain Treated with Steroids and Antibiotics. Annual Meetingof the North American Neuro-Ophthalmology Society
Keynote Presentation, From Watching to Seeing: Surabaya, Indonesia 2012Retinal Signaling and Polymodal Integration of Sensory Information. Fifteenth International Multiconference on Cognitive Sciences, Jozef Stefan Institute
Featured Speaker, Zion Bank’s “Speaking on Business,” Salt Lake City, UT 2012KSL and KUTV. The KSL piece was distributed nationally
David Krizaj, PhD Invited Speaker, Retinal Glia: Glue, Feeders, Protectors, Snowbird, UT 2012and Mischief Makers. Neurobiology and Glia Symposium
Keynote Presentation, From Watching to Seeing: Ljubljana, Slovenia 2012Retinal Signaling and Polymodal Integration of Sensory Information. Fifteenth International Multiconference on Cognitive Sciences, Jozef Stefan Institute
Platform Presentation, Trpv4 Channels Modulate Steamboat, CO 2012Neurons. Federation of American Societies forExperimental Biology, Summer Research Conference on Retinal Processing
Platform Presentation, Polymodal TRPV4 Signals in Berlin, Germany 2012Retinal Ganglion Neurons. International Society for eye research
Platform Presentation, Diverse Mechanisms Mediate Snowmass, CO 2012TRPV4’s Polymodal Responses. Presented by D. Ryskamp. Summer Research Conference on Calcium Signaling, Federation of American Societies for Experimental Biology
Research Presentation, The Roles, Properties, and Ashburn, VA 2012Consequences of Mechanosensation in the Retina. Presented by D. Ryskamp. Janelia Farms
SIG Presentation, Mechanosensation, TRPV4 Signaling Ft. Lauderdale, FL 2012and Neurodegeneration in the Mammalian Retina. Annual Meeting of the Association for Research in Vision and ophthalmolog
Invited Seminar, TRPing the Retina: Role of Augusta, GA 2012Nonconventional Calcium Signals in Mechanosensation, Visual Behavior, and Disease. Georgia Health Sciences University
Nick Mamalis, MD Correction of Postoperative Refractive Surprises after Athens, Greece 2012Brunescent Cataract. Twenty-sixth International Congress of the Hellenic Society of Intraocular Implant and Refractive Surgery
The ASCRS/ESCRS Survey on Foldable IOLs Requiring Vienna, Austria 2012Explantation or Secondary Intervention, 2010 Update.Mamalis N, Fuller S, Kavoussi S, McIntyre J. Vienna. 2011 XXIX Congress of the European Society of Cataract and Refractive Surgeons
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Pathologic Comparison of Asymmetric or Sulcus Milan, Italy 2012Fixation of Three-piece Intraocular Lenses with SquareVersus Round Anterior Optic Edges. Mamalis N, Bodnar Z, Werner L, Leishman L, Ollerton A, Michelson J, Strenk S. Milan 2012 XXX Congress of the European Society of Cataract and Refractive Surgeons
Strategies and Techniques for IOL Exchange (A). Vienna, Austria 2012Tassignon MJ, Auffarth G, Mamalis N, Tetz M, Masket S
Cataract Surgery in Pseudoexfoliation Patients. Maui, HI 2012Hawaiian Eye 2012, Grand Wailea Resort
Toxic Anterior Segment Syndrome. Buffalo Buffalo, NY 2012Ophthalmology Symposium, Olmsted Center for Sight
Symposium/Moderator, Cataract. Controversies in Chicago, IL 2012in Cataract and Refractive Surgery. Correction of Refractive Surprises: Lens-based Versus Laser Correction. The ASCRS-ESCRS Survey of Foldable IOLs Requiring Explaintation or Secondary Intervention. Toxic Anterior Segment Syndrome: Update on Most Common Causes. Assessment of Single-piece Hydrophilic Acrylic and Silicone IOLs for Sulcus/Piggyback Fixation in Pseudophakic Cadaver Eyes. Evaluation of Capsular Bag Opacification With New Disc-shaped Hydrophilic Acrylic Foldable IOL in Rabbit Model. Pathological Assessment of Complications with Asymmetric or Sulcus Fixation of Square-edged Hydrophobic Acrylic IOLs. Pathological Comparison of Sulcus Fixation of 3-piece IOLs with Square or Round Anterior Optic Edges. Effective Communication Skills (Tips for Public Speaking/Writing. American Society of Cataract and Refractive Surgery
Risk Factors for Toxic Anterior Segment Syndrome, Chicago, IL 2012(Best Paper of Session). Pathologic Comparison of Asymmetric or Sulcus Fixation of 3-piece IOLs with Square vs. Round Anterior Optic Edges (Original Paper). Toxic anterior Segment Syndrome Following anterior Segment Surgery, Roundtable Moderator. Cataract Surgery in the Setting of Ocular Comorbidities and High-risk Features for Intraoperative and Postoperative Complications. Astigmatism in the Cataract Patient. IFIS: Clinical Update (Case 7 in Spotlight on Cataract: Clinical Decision-making with Cataract Complications. One-stop Chop Squad. ThePathology of Exfoiliation: Are the Canal and Collectors Affected? Spotlight on Pseudoexfoliation. Phacoemulsification and Advanced Techniques. American Academy of Ophthalmology/Asia Pacific Academy of ophthalmology
Majid Moshirfar, MD Ocular Surface Complications Associated with Acute Salt Lake City, UT 2012Blepharitis. ALCON Meeting
Dry Eye: A Disease that May Progress. ALLERGAN- Boise, ID 2012SCS-core Meeting
Dry Eye: A Disease that May Progress. ALLERGAN- Salt Lake City, UT 2012SCS-core Meeting
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Randall J olson, MD 2012 Binkhorst Lecturer, Where Are We on the Road Chicago, IL 2012to Optical Perfection? Symposium on Cataract, IOL, and Refractive Surgery. American Society of Cataract and Refractive Surgery
Talk Title: Cataract Surgery in the Face of a PKP. Chicago, IL 2003–presentCataract Surgery in the Setting of Ocular Comorbidities and High-risk Features for Intraoperative and Postoperative Complications. Annual Meeting, American Academy of ophthalmology
Senior Instructor, Advanced Phaco Labs. American Chicago, IL 2012Learning Phaco Chop. Latest on POE, Advanced Phacoemulsification Session. American Academy of ophthalmology
Session Moderator, White Lens + Uveitis. Eleventh Chicago, IL 2012Annual Spotlight on Cataract Symposium, American academy of ophthalmology
Intraocular Surgery, Surgical Techniques. Toxic Chicago, IL 2012anterior Segment Syndrome Following cataract Surgery. american Society of cataract and Refractive Surgery
Session Moderator, Advanced Phaco Skills. Senior Chicago, IL 2012Instructor, Learning Phaco Chop: Pearls and Pitfalls.American Society of Cataract and Refractive Surgery
Personal Experience with the Catalys System. Chicago, IL 2012Eyeworld Symposium, American Society of Cataract and Refractive Surgery
Presentation, Wound Burn: Causation and Prevention. Vail, CO 2012Twenty-ninth Annual Johns Hopkins Current Concepts in ophthalmology conference
Speaker, What We Know About PBK Prevention. Gainesville, FL 2012Fiftieth University of Florida Department of Ophthalmology Anniversary Meeting and Scientific Meeting, Hilton Conference Center, University of Florida
Speaker, Fundraising: Key to the Future. Innovation. Miami, FL 2012University Professors of Ophthalmology MeetingsCaucus on Translational Research. A Business Plan for Chair Tenure. Top Ten Management Problems. Association of University Professors of OphthalmologyMeeting
Speaker, Other Concerns Surrounding Intraoperative Maui, HI 2012Aberrometry. Hawaiian Eye Nursing Meeting
Speaker, Surgical Management of IFIS. Some Maui, HI 2012Concerns about Relying on Intraoperative Aberrometry. Non-surgical Means of Correcting Post-surgical Refractive Error. Hawaiian Eye Conference
Bhupendra C K Patel, MD, FRCS, FRC Cosmetic Surgery Forum. Facial Cosmetic Surgery Meeting Las Vegas, NV 2012
Jeff Pettey, MD Effective Communication during Patient Encounters. Salt Lake City, UT 2012Resident Lecture. John A. Moran Eye Center
P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E
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Geoffrey Tabin, MD International Opportunities for Young Ophthalmologists. Chicago, IL 2012Clinical Decisions in the Management of Complications of Cataract and IOL Surgery. Manual Extracapsular Cataract Extraction (ECCE/SICS). Surgery: Indications andTechniques. American Academy of Ophthalmology
Life Long Vision Foundation. The Eye Ball St. Louis, MO 2012
International Ophthalmology. Canadian Canada 2012ophthalmology Society
Impossible Dreams—The Ascent of Everest and Eradicating Salt Lake City, UT 2012World Blindness Program. The 33rd Annual Technical Staff Education.
Monica Vetter, PhD Genentech, Neuroscience Research Department Palo Alto, CA 2012
Harvard Medical School, Massachusetts Eye and Boston, MA 2012Ear Infirmary
Medical College of Wisconsin, Department of Milwaukee, WI 2012Cell Biology, Neurobiology & Anatomy
Gordon Research Conference on Visual System New London, NH 2012Development, Colby-Sawyer College
CSVT - Acute and Chronic Management and Concerns. Salt Lake City, UT 2012Stroke Conference, University of Utah
Albert T Vitale, MD Combined PPV and Phaco-IOL for Uveitis. Eighth Halkidiki, Greece 2012International Symposium of Uveitis (IUSG)
Invited Speaker: Is It Birdshot Retinochoroidopathy, Chicago, IL 2012and If So, How Should I Treat It? American Academy of Ophthalmology, Uveitis Sub-specialty Day
Panel Discussion: Uveitis Potpourri. American Academy Chicago, IL 2012of Ophthalmology, Uveitis Sub-specialty Day
Invited Speaker: Multimodal Imaging in Uveitis, and Orlando, FL 2012Diagnosis and Treatment of Uveitis. American Academy of ophthalmology
Invited Speaker: Diagnostic and Therapeutic Vitrectomy in San Francisco, CA 2012Uveitis. Cal Pacific
Poster Presentation: Macular Retinal Vasculitis Fort Lauderdale, FL. 2012and Choroiditis Associated with Wegener's Granulomatosis: Case Series. Vitale AT, Lim LT, Shelton J, Vasudevan V, Moorthy R. Association for Research in Vision and ophthalmology
Judith E A Warner, MD WINO Hot Topics in Neurology, NMO: What’s New? Salt Lake City, UT 2012
Neuro-ophthalmology Fall Festival Boston, MA 2012
NANOS: Hot Topics in Neuro-ophthalmology, Utah Artificial San Antonio, TX 2012Vision Project: Occipital Cortical Implants for Blindness
CSVT: Acute and Chronic Management and Concerns. Salt Lake City, UT 2012Stroke Conference, University of Utah
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Liliana Werner, MD, PhD Winter Update. american Society of cataract and Playa del Carmen, Mexico 2012and Refractive Surgery
Afonso Fatorelli Lecture, The XII International Congress São Paulo, Brazil 2012on Cataract and Refractive Surgery
The 26th Congress of the Deutschsprachige Berlin, Germany 2012Gesellschaft für Intraokularlinsen-Implantation und Refraktive Chirurgie (DGII)
Keynote Speaker, Annual Cataract Course Ayr, Scotland 2012
Barbara M Wirostko, MD Human Growth Hormone Delivery from PEA Fibers Dublin, Ireland 2012for the Treatment of Corneal Wounds. John Zupancich, Julien Bérard, Hecka A, Kemp A, Muller M, Mihov G, Reiver S, Messier K, Thies J, Wirostko B, Rafii MJ. Twenty-second Annual BioInterface Conference, University College
Human Growth Hormone Delivery from PEA Fibers New Orleans, LA 2012for the Treatment of Corneal Wounds. John Zupancich, Julien Bérard, Hecka A, Kemp A, Muller M, Mihov G, Reiver S, Messier K, Thies J, Wirostko B, Rafii MJ. Sixteenth Symposium on the material Science and Chemistry of Contact Lenses
Invited Speaker, Early-stage Startup Companies: Ft. Lauderdale, FL 2012Strategies for entrepreneurship in ophthalmology. ARVO Education Course
Safety and Efficacy of a Novel Topical Rho Kinase Ft. Lauderdale, FL 2012Inhibitor ATS8535 In Vivo. Wirostko B, Umeno H, Hsu H, Kengatharan M. Abstract #. 5079. Association for research in Vision and ophthalmology
Sustained Delivery for Glaucoma. March Meeting, New York, NY 2012american Glaucoma Society
Jun yang, PhDyang, PhDy Current Understanding of the Usher 2 Complex, Fort Lauderdale, FL 2012Retina Ciliopathies: From Genes to Mechanisms and Treatment. Elsevier: 14th Vision Research Conference
Podium Presentation, Whirlin Modulates the San Diego, CA 2012Actin-regulatory Function of Espin. Midwinter Meeting, Association for Research in Otolaryngology
Functional Exploration of the Usher Syndrome Type 2 Salt Lake City, UT 2012Complex. Membrane Trafficking Minisymposium, University of Utah
Marielle young, MDyoung, MDy Pediatric Ophthalmology, Association for the Education Salt Lake City, UT 2012and Rehabilitation of the Blind and Visually Impaired. Division of Services for the Blind and Visually Impaired
Timing of Surgery and Nystagmus in Patients with Salt Lake City, UT 2012Bilateral Infantile Cataracts. Clinical Faculty Day, John A. Moran Eye Center, University of Utah
Diagnosis and Management of Ocular Torsion Disorders. Salt Lake City, UT 2012Infantile Cataracts. North Star Optometry Seminar, John A. Moran Eye Center, University of Utah.
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