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Teloken C., Dal’Asta I., Coelho L., Graziottin T. 16 th World Meeting on Sexual Medicine October 2014 São Paulo Brazil Abstract Number: # 014 TUNICA ALBUGINEA CRURAL GRAFT FOR SEVERE PENILE CURVATURE (TACRUG) DUE TO PEYRONIE'S DISEASE: 10 YEARS FOLLOWUP Federal University of Health Sciences – UFCSPA & Santa Casa Hospital Porto Alegre – Brazil

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Page 1: Federal University of Health Sciences – UFCSPA & Santa ... · Porto Alegre – Brazil. Surgery management of severe penile deformity due to Peyronie’s disease is challenging

Teloken C., Dal’Asta I., Coelho L., Graziottin T. 

16 th World Meeting on Sexual Medicine  ‐ October 2014  São Paulo  Brazil

Abstract Number: # 014 

TUNICA  ALBUGINEA  CRURAL  GRAFT  FOR  SEVERE  PENILE CURVATURE (TACRUG) DUE  TO PEYRONIE'S  

DISEASE:  10  YEARS  FOLLOW‐UP

Federal University of Health Sciences – UFCSPA & Santa Casa HospitalPorto Alegre – Brazil

Page 2: Federal University of Health Sciences – UFCSPA & Santa ... · Porto Alegre – Brazil. Surgery management of severe penile deformity due to Peyronie’s disease is challenging

Surgery management of severe penile deformity due to Peyronie’s

disease is challenging.

GOLD STANDARD  ??

Page 3: Federal University of Health Sciences – UFCSPA & Santa ... · Porto Alegre – Brazil. Surgery management of severe penile deformity due to Peyronie’s disease is challenging

Incision and grafting1. Fascia (temporalis, rectus abdominal)2. Pericardium3. Dermal (graft or flap)4. Buccal mucosa5. SIS (porcine small intestinal submucosa)6. Saphenous vein7. Cadaveric fascia lata8. Fascia lata9. Tunica vaginalis10. Tunica albuginea crural graft (TACRUG) 

(We first described (Teloken et al. JUrol 164(1):107-8, 2000.

Page 4: Federal University of Health Sciences – UFCSPA & Santa ... · Porto Alegre – Brazil. Surgery management of severe penile deformity due to Peyronie’s disease is challenging

suboptimal  long‐term results

‐ curvature recurrence ‐ erectile dysfunction‐ infection‐ abnormal scars‐ penile: numbness, shortness

Page 5: Federal University of Health Sciences – UFCSPA & Santa ... · Porto Alegre – Brazil. Surgery management of severe penile deformity due to Peyronie’s disease is challenging

Ideal graft‐ Autologous‐ Patients’s tunica albuginea‐ Same  tissue, same physical characteristics(tensile strength, compliance and flexibility)

‐ No antigenicity or infection transmission risk‐Minimal tissue inflamation‐ Not imposing adittional costs, such is the case for  synthetic and processed organic compounds  

Porto Alegre                                                                                    Brazil 

UFCSPA – Federal University                                                  Santa Casa Hospital

Page 6: Federal University of Health Sciences – UFCSPA & Santa ... · Porto Alegre – Brazil. Surgery management of severe penile deformity due to Peyronie’s disease is challenging

1. severe penile curvature, narrowing, or  indentation 2. deformity precluding coitus3. severe penile shortening4. preserved erectile function5. ED responding to PDE5 inhibitors

Candidates for surgery

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Patients 

‐ chart reviewed ‐ preserved erectile function  or ED responding to PDE‐5 inhibitors 

‐ stable penile deformity precluding vaginal intercourse. 

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Methods:‐ Penile degloving‐ Plaque incision‐ Measurement of the defect‐ TACRUG is obtained through a 3‐cm longitudinal perinealincision. 

‐ A longitudinal segment of proximal corpus cavernosum 2mm larger than the defect is delimited with methylene blue. 

‐ preserving the cavernous artery entry point‐ segment of tunica from the contralateral corpus cavernosummay also be retrieved if necessary. 

‐ The corpus caversonum then is closed with running 4‐0 polyglactin suture. 

‐ Graft is tailored according to the gap to be occluded.

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PICTURE 1

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Picture  6 

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Picture 7 

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Picture  8

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Picture 9 

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Picture  10

unilateral corpuscavernosum

scrotum

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scrotum

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Picture  11

Graft size determination

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Graft beeing wihdrawn

PreservingCorpus 

cavernosummuscle

Picture  12  

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Picture  13

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Picture   1

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Neurovascularband beforecovering graft

Picture 15

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Picture 16

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Picture  17

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TACRUG  ‐ RESULTSmean age 54 yo (42 – 75)

10  years

N               %148           100

ED 20               14

P. shortening 13                 9

Penile implant 19               12,8

P. numbness 22               15

Curvaturerecurrence

12                 8    

fail PDE5‐i    nihil

straight penis*

89

(*) Willing to undergo again

Page 34: Federal University of Health Sciences – UFCSPA & Santa ... · Porto Alegre – Brazil. Surgery management of severe penile deformity due to Peyronie’s disease is challenging

TACRUG  ‐ RESULTSMean follow‐up months 35 65 78 10 years

N                 % N                 %78

N                  %102

N              %148

ED 5               17,8 09             14,5 10                10 20 14

P. shortening 15             53  7                 8,9 07                7,14 13               9

Penile implant 14                 20 19              12,8

P. numbness 06            21,4 12             15,3 10 22              15

Curvaturerecurrence

4           14,3     6                 7,6 8 12                8

fail PDE5‐i   16 6

straight penis * 85,7 89,7 81,7 89

(*)  Willing to undergo again

Page 35: Federal University of Health Sciences – UFCSPA & Santa ... · Porto Alegre – Brazil. Surgery management of severe penile deformity due to Peyronie’s disease is challenging

TACRUG  CONCLUSION‐ graft easily obtained‐ does not carry the risk of rejection or transmission of  infectious  diseases 

‐ does not add costs ‐ affords  satisfactory  long‐term results. ‐ overall complications rate (curvature recurrence , ED, sensibility 

‐ No jeopardize those who require penile implant‐ postoperative result as excellent or satisfactory 81.7%