Experimental designCourse development

NSS

Thursday 10 Nov

Set up standard strategy for example description in R and MS-word

•Aknowledgment to investigators (name, time, location, …)•Research question, hypothesis to test•Description of experiment and design

– Crossed nested– Fixed random

•Description of logical model•Dataset in csv format•Metadat•Tabular and graphical representations of design and data.

– Outliers, MV.– First exploratory glimpse on the information– Check replication

•Analysis– Test preconditions of model– ANOVA– GLM– Multiple comparisons

•Tabular presentation of results•Graphical presentation of the results•Add any multimedia information, like images, animation… to increase appeal of the exp (images

of field plots, demonstrating design aspect, measurements, preparations, labs, …)

Set up standard strategy for example description in R and MS-word

•Responsibilities– 3 IUC partners engage in finding good examples– Document the examples along to the template– Write R-code– Distribute for discussion– Increase realism and appeal with images, animations, …– Investigate possibilities for interaction on the WWW– Upload to dropbox or later to WWW

•Deadline end of January 2012•Proposal. Each team fully develops a

certain amount of examples along to template

Investigate possibilities for interaction on the WWW

• Open possibilities for the student to investigate more on experimental designs in database– Balanced => unbalanced– From CRD => RCBD => LS, fi GH applet– Play with nr of blocks, replications, ….– ….

Set up standard strategy for example description in R and MS-word

•Responsibilities

– Jimma: Yehenew Getachew•RCBD, 2 F. Fully crosed

•Split plot

•greco-latin sq

Set up standard strategy for example description in R and MS-word

•Responsibilities

– Cuenca: Vladimiro Tobar•RCBD, 1 F

•?

Set up standard strategy for example description in R and MS-word

•Responsibilities

– Colombia, Bucaramanga: Daniel Martinez•RCBD, 1 F

•Repeated measures

•….

Set up standard strategy for example description in R and MS-word

•Responsibilities

– Colombia, Bogota: Carlos Bojaca•CRD, more F

•RCBD, 1 F

•Repeated measures

•NlMixed

•….

Set up standard strategy for example description in R and MS-word

•Responsibilities– UNALM: – Felipe de Mendiburu, Ivan Soto, Ana

Vargas.•Alpha•Lattice•Augmented design•Split Plot•Split split plot•Strip Split Plot

Set up prerequisites for DOE course, both practitioners and stats staff

•Baby statistics => DOE

•If NO baby stats– Statistical concepts– Linear models

•Simple regression?•More?

Set up of basic outline DOE course

•Basic concepts of experimental design

•Exp with 1 factor

•Full factorial exp with 2 factors

•Exp with more factors

•Fixed Random

•Nesting

•Designs

•Specialised topics

Set up of basic outline DOE course: KUL

Applied Linear Statistical Models

5th Edition

Kutner - Nachtsheim – Neter - Li

McGraw-Hill International Edition 2005

ISBN: 007 – 112221 - 4

5 credits

2de sem of 3th Bac Bioscience Engineering

26 + 26 h contact, lect + practice

ANOVA

- Equal replications per cell

- 1 obs per cell

- Unequal replications per cell

- Missing cells

More factors (fixed, crossed)

Nested factors

Design

2 factors (fixed, crossed) Principles

- Randomisation- Replication

Design structures

-Blocks-Complete-BIB

- Repeated measurements- Split-plots-(Fractional designs)

Mixed models (fixed + random)

Schematic outline: DOE at practitioners

Additionally

• ANOVA GLM

• ANOVA Diagnostics

• ANCOVA

• Coding, Contrast…GLM?

• Multiple comparisons

• Type 1 SS => Type 3 SS

Time tables

• UNALM: 14 weeks: 3 h/w Lect + 2 h/w Prac

• Jimma: 16 weeks: 2 h/w Lect + 3 h/w Prac

• KUL: 13 weeks: 2 h/w Lect + 2 h/w Pract

• Contact Ivan Soto for outline DOE

Possible extra specialized modules in DOE course

•Design and analysis of mixture experiments•Response surface methodology•DOE in systems analysis•Optimal experimental design theory•Optimal design for nonlinear models•Super saturated designs•Nonparametric alternatives•Fractional factorials•Power analysis•….

Organisation Cuenca, Jimma

•4 days too much, 2 days!•Planning?•Dropbox, mail, file exchange, ……•When Cuenca? April 2012– TD

•Training for practitioners. Cuenca and other Ec U

•When Jimma? Jan-Feb 2013•….