environmental health and safety at...

Environmental Health and Safety

at Invitrogen

Improving the human condition

Focusing on health and safety →

Supporting environmental sustainability →

Maintaining regulatory compliance →

Dedicated to product stewardship →

2

As a company involved in improving the human condition, Invitrogen is dedicated to protecting the environment and pro-

moting the health and safety of our employees, customers, and citizens in the communities in which we operate.

Invitrogen’s Quest calls for accelerating the search for improvements in the human condition through innovations in sci-

ence and technology that expand biological understanding. Our EHS mission aligns with Invitrogen’s Quest by focusing on four

building blocks: (1) occupational health and safety, (2) environmental sustainability, (3) regulatory compliance and (4) product

stewardship.

Our EHS mission

Our mission is to achieve excellence through sustainable EHS practices. With passion, a sense of urgency, and integrity we

focus on four building blocks.

These building blocks shape our culture globally, better positioning Invitrogen to serve as a responsible steward in the

global life science community.

Health & safety

Provide a safe workplace for employees and contractors

Environmental sustainability

Protect the environment where ourbusiness has an impact

EHS regulatory compliance

Comply with all applicable EHS laws and regulations

Product stewardship

Develop innovative products that are safer and environmentally sustainable

www.invitrogen.com

3

Our EHS policy

To achieve our Mission, Invitrogen has a global EHS policy that applies to all employees and contractors. We are committed to

the principles outlined below.

ComplianceMonitor, prepare for, and respond to EHS regulations globally•Develop policies and procedures founded on full compliance with all applicable EHS regulations•Conduct internal audits to ensure compliance with regulatory and internal requirements•Establish strong relationships with EHS regulatory agencies•

Prevention Strive to prevent employee and other stakeholder injury or illness •Promote a culture of active employee participation to eliminate, isolate, or minimize workplace hazards that could affect the welfare of our •employees or the environmentUndertake the prevention of any harmful environmental impact that could result from our operations or products •Establish and practice effective emergency and contingency plans for every location where we operate•

Product lifecycleEndeavor to eliminate or minimize the use of hazardous substances or excess materials in our products, packaging, and processes•Contribute to the provision of products that can be handled and disposed of safely by all our customers globally•

Global stewardshipPromote environmentally sustainable operations and products•Design, build, and operate our facilities to conserve natural resources and limit our impact on climate change. For us, it means water conserva-•tion, energy efficiency, waste minimization, and carbon footprint reduction Promptly respond and attend to any community complaints •Promote business agreements along the supply chain with organizations that incorporate effective EHS programs •

Communication Communicate EHS achievements and shortcomings to internal and external stakeholders•Train to disseminate awareness of health and safety issues and their impact on all employees•

Continuous improvementUse effective systems, metrics, and goals to drive continual improvement of our EHS performance•Implement an EHS strategy to continuously enhance and expand the EHS footprint along the supply chain•

Greg T. Lucier, President and CEO Cristina Amorim, Senior Director, Global EHS

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Our EHS goals

Aligned with our four building blocks in the EHS mission, we established a goal-setting process to continuously improve

performance. The process establishes 4-year goal periods and includes monthly progress reports, followed by evaluation of

resource allocation to ensure targets are met at the end of the goal period.

Our first 4-year goal period started in 2004 and ends in 2008. At the end of 2008, we will evaluate our progress and set

out new performance goals for the next 4-year period.

Health & safety



Product stewardship

•Reduceourinjury/illnessandDART*ratesby25%

Complete100%ofnewproductassessmentsforMSDS,labelcontent,and•

shipping information

Energyefficiency:Reduceenergyconsumptionby10%,indexedtonetsales•

Climatechange:ReduceCO• 2emissionsby10%,indexedtonetsales

Waterconservation:Reducewaterconsumptionby10%,indexedtonetsales•

Wasteminimization:Reducewastedisposalby10%,indexedtonetsales•

Zero Notices of Violation•

Our 2004–2008 EHS goals:

* DART (days away + restricted time cases)

www.invitrogen.com

5

Invitrogen is committed to promote the health and

safety of our employees, our customers, and the citizens

in our communities. We use U.S. Occupational Safety and

Health Administration (OSHA) guidelines to report all work–

related injuries and illnesses globally. We express this as a

rate, based on 100 employees working 2,000 hours annually.

We measure health and safety performance against

two metrics: (1) OSHA recordable injury and illness rates and

the(2)daysawayandrestrictedtime(DART)rate.

Our goal is to reduce the recordable injury/illness

and DART rates by 25% for 2004–2008.

During the period 2004–2007, our injury and illness and

DARTratesdecreasedby16%and32%respectively.Asof

the end of 2007, we are maintaining the lowest, injury and

illness rate since 2002, and we expect to meet our target

set for 2008.

This improved performance is a result of active incident

reporting and investigation, as well as root-cause analysis.

As our safety culture matures, we have realized increased

levels of employee accountability and ownership to safety,

which will result in further improvements.

Unfortunately, in 2006, the injury & illness andDART

rateswere25%and20%higher,respectively,thanthepre-

vious year. This increase was largely attributed to repetitive

strain problems and manual handling issues. We continue

to implement health and safety programs to reduce these

types of injuries.

As we complete our 20th anniversary this year, we are

proud to have zero work-related fatalities since Invitrogen

was established.

Asia Pacific region achieved 1 million hours worked without a lost-time case in November 2004 →

Carlsbadachieved2millionhoursworkedwithoutalost-timecaseinOctober2005 →

Madisonachieved2millionhoursworkedwithoutalost-timecaseinOctober2006 →

Eugene achieved 1 million hours worked without a lost-time case in September 2007 →

Health and safety

Workplace injury and illness rates (global)(Based on 100 employees working 2000 hours annually)

0

0.5

1.0

1.5

2.0

2.5

2004 2005 2006 2007 2008

1.5

1.9

1.6

1.0

2.0

1.2

1.6

1.3

Baseline

25% reduction

RecordablesDART (days away + restricted time cases)

Target

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Sustainability is an ongoing process to adapt how we operate to reduce our environmental footprint. Climate change,

resource conservation, and waste reduction are key elements of our environmental agenda. While our sustainability process

is in its early stages, we are making significant progress towards our goals.

Energy efficiency

Energy use is the most critical aspect of our environmental

impact. In 2004, we issued a Global Energy Conservation

Policy to improve our global energy efficiency. We report our

energy consumption in gigajoules, indexed by million of dol-

lars in net sales. We also expect to reduce the energy costs

at our manufacturing facilities, which has a direct impact on

operating costs.

Our goal is to reduce our energy consumption by

20% (indexed to net sales) for 2004–2008.

Cogeneration in Norway transforms waste into energy—every year, 840 tons of flammable hazardous waste are burned, generat-ing heat energy to keep offices warm. The practice reduces energy use and prevents waste from causing potential environmental degradation.

With the implementation of a number of energy-savings

initiatives,wehavereducedourenergyconsumptionby35%

per unit of sale during 2004–2007. We are well underway to

surpass our 2008 goal.


Energy consumption (gjoules/US $million of sales)

Baseline10% reduction

Target

700

600

500

400

300

200

100

02004 2005 2006 2007 2008

658

548

494

427Mark Smedley, VP Global Operations; Larry Nicholson, Director of Facilities in Carlsbad; Cristina Amorim, Sr. Director of Global EHS—discussing the LEED® (Leadership in Energy and Environmental Design) certification and energy savings for our new building in Carlsbad.

www.invitrogen.com

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Morethan80%ofourCO2 emissions result from our energy

use. Therefore, our progress towards energy efficiency cor-

relates directly with our reductions in CO2 emissions. Dur-

ing 2004-2007, we decreased our CO2 emissions per unit of

salesby20%.Wearewellpositionedtomeetourtargetset

for 2008.

Climate change

Perhaps the most challenging global issue of our time, cli-

mate change has the potential to dramatically impact the

worldwelivein.Reducingemissionsofgreenhousegases

that increase the earth’s temperature is a core element of

our environmental sustainability agenda. We are commit-

ted to the “cooling of Global Warming.”

We calculate CO2 emissions from the energy and natu-

ral gas we consume. As we improve our reporting mecha-

nisms, we will include CO2 emissions from business travel

and dry ice usage.

Our goal is to reduce CO2 emissions by 10% (indexed

to net sales) for 2004-2008.


In Eugene, OR, Fatipule Pasi works in a fume hood which is designed for protection of the employees while conserving energy.

Baseline10% reduction Target

100

90

80

70

60

50

40

30

20

10

02004 2005 2006 2007 2008

CO2 emissioins (CO2 Tons/US$ million of sales)

89

74

64

55

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Over half of our total water usage is in our Cell Culture Divi-

sion, with manufacturing sites in Grand Island New York;

Inchinnan, United Kingdom; as well as Auckland, New Zea-

land; and Christchurch, New Zealand. By applying Lean Six-

Sigma tools, we have reduced water usage at these sites,

which contributed to a 12% decline in total water con-

sumed during the 2004-2007 period, indexed by net sales.

We continue to monitor manufacturing processes at these

locations to identify further water conservation opportunities.

Water conservation

All of our products use water, whether mixing or diluting

active ingredients or cleaning and washing equipment used

in the manufacturing process. We constantly evaluate ways

to reduce water usage in our manufacturing processes and

reuse water to the maximum extent possible.

Our goal is to reduce our water consumption by 10%

(indexed to net sales) for 2004–2008.


In Inchinnan, UK, Geoff Fowler presents his water conservation project on Find a Better Way Day.

450

400

350

300

250

200

150

100

50

Baseline10% reduction Target

Water consumption (m3/US$ million of sales

2004 2005 2006 2007 2008

397362 351 348

In2006,ourInchinnan,UnitedKingdomsiteimplementedaprojectthat,byfixingfaultyequipmentandimplementingsmart →processess, saves 13,870 cubic meters of water per year.

TheAukland,NewZealandsitereduceditsannualwaterusagefrom46,800cubicmetersbetween2002and2004to31,351 →cubic meters in 2007

www.invitrogen.com

9

Waste minimization

We strive to minimize the hazardous and nonhazardous

waste generated at our operating sites. Hazardous waste

includes hazardous chemical, biohazard, and radioactive

waste and any expired or rejected hazardous products.

Our goal is to reduce waste disposal by 10% (indexed

to net sales) for 2004-2008.

Our hazardous waste generation per unit of sales increased

by 27% from2004 to 2005. This is due to the acquisition

of more chemical-intensive business that added hazardous

waste to our portfolio. Since 2005,we havebeen consis-

tently decreasing the generation of hazardous waste per

unit of sale and we expect to meet our 2008 target.

During the period of 2004-2007, we reduced the genera-

tionofnonhazardouswasteperunitofsalesby17%.Our

waste reduction and recycling initiatives have kept many

tons of waste from going to landfills.


Hazardous Waste Generated (kg)/US $Million (Sales)700

600

500

400

300

200

100

02004 2005 2006 2007 2008

472

599

497

398

Baseline 10% Reduction Target

Baseline10% reduction

Nonhaz. waste Total recycle

Target

2000

1800

1600

1400

1200

1000

800

600

400

200

02004 2005 2006 2007 YTD 2008

Nonhazardous waste generated and recycling (kg/US $millions of sales)

1762

377

1402

1089

1517

625

1487

713

Going greener and cheaperIn2006,ourEugenesitesubstitutedsodiumazidewithsodiumhypochloriteinitslatexdialysisprocess.Sodiumhypochlorite →isanapprovedsubstancethatcanbesafelyreleasedintocitywastewater.Eliminatingmorethan5,200gallonsofsodiumazidewaste saved the company almost $30,000 in waste disposal costs in one year.

In2004,theInchinnansiteworkedonaninitiativethatprevented170tons/yearofbottledliquidwastefrombeingdisposed →in landfills. The liquid is now removed from the product in a bottle crusher sent for off-site treatment.

TherecyclingprogramatInchinnanhasalsodiverted40tons/yearofcardboardandofficepaperfromlandfills. →

InCarlsbadin2007,morethan26tonsofelectricalequipmentwastehavebeenrecycled,preventingitfromgettingtothe →landfills.

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We had no NOVs in 2004 and 2006. However, despite

our efforts, we received an NOV from OSHA at our site in

Eugenein2005.In2007,wereceived3NOVsfromtheSan

Diego County Department of Environmental Health at our

site in Carlsbad and 2 NOVs from the U.S. Federal Aviation

Administration at our site in Eugene. We have diligently

implemented corrective actions to prevent these non-

compliance from reocurring.

In Eugene, OR, Deputy Fire Marshal, Greg Musil and EHS Manager, Jennifer Olson, conducting a site inspection on December 11, 2007.

We are committed to comply with all applicable laws and

regulationswhereverweoperate.Requirementsformoni-

toring and complying with regulations as well as permit

management are spelled out in the Compliance Phase I

section of our Global EHS Achievement Program (see page

12). We audit our sites regularly to ensure that permit dis-

charge limits and reporting requirements are met.

We measure our regulatory compliance by tracking

Notices of Violation (NOVs), which are written notices from

a regulatory agency identifying non compliance.

Our goal is to have ZERO Notices of Violation for

2004-2008.

50

45

30

35

30

25

20

15

10

5

02004

InspectionsNotice of violations

2005 2006 2007 2008


Cou

nt

www.invitrogen.com

11

Product stewardship

Jerry Moloney and Bob Matanane demonstrating proper packaging and labeling on a dangerous goods shipment.

Our product safety team plays a vital role in product stew-

ardship through active involvement with new product

introductions, product lifecycle management, and new

acquisitions.

We support global operations and our customers by

assessing our product formulations and generating Mate-

rial Safety Data Sheets (MSDS), labeling content and direc-

tives for international and domestic transport of hazardous

materials.

Our goal is to complete 100% of new product assess-

ments for MSDS, label content, and shipping infor-

mation for 2004–2008.

Since 2004, we have made a number of infrastructure

improvements that enable us to timely complete assess-

ments of new products in a timely manner. With the imple-

mentation of The Wercs®, an MSDS authoring platform, and

Agile PLM, a product lifecycle management tool, we are

equipped to meet our goal.

ThroughcollaborationwithR&D,manufacturing,mar-

keting, and EHS departments, Invitrogen is working to drive

innovation around the design and development of more

ecologically sensitive product offerings. These products are

designed to reduce or eliminate the use or generation of

hazardous materials and excessive packaging. For instance,

SYBR®SafeandSimplyBlue™SafeStainweredesignedto

offer more ecologically sensitive alternatives to other com-

monly used laboratory reagents.

We are in the process of defining how we will measure

the progress of our ecologically sensitive product offering.

More information on the growing and exciting area of envi-

ronmental stewardship will be available in the future.

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EHS management systems

At Invitrogen, the EHS organization uses a comprehensive,

umbrella type approach to manage EHS functions along

the supply chain, from suppliers, through manufacturing,

R&D,anddistributionsites,toourcustomers.

The umbrella approach consists of the Global EHS

Achievement Program and the Global EHS Audit Program.

Both programs are applied with the same level of rigor to

all of our sites and stakeholders globally; whether a site

or stakeholder is in Europe, the Asia-Pacific region, or the

United States; they are held to the same standard.

The Global EHS Achievement Program consists of inter-

nal requirements divided into three evolving levels: compli-

ance, prevention, and leadership.

Global EHS Achievement Program

ComplianceManagement Systems I

Emergency Response Management

Hazardous Material Management

Hazard Communication

Radioactive Materials Management

Lock out/Tag out

Personal Protective Equipment

Respiratory Protection

Hearing Conservation

EHS Training

Workplace Exposure Assessment

Confined Space Safety

Biohazardous Material Management

Waste Management

Regulatory File Management

Environmental Permit & License Management

Incident Reporting and Investigation

Powered Industrial Trucks & Traffic Mgmt

PreventionManagement Systems II

Safety Committee

Complaint/NOV Reporting & Investigation

Product/Process/Equipment Transfer

Process Safety and Risk Management

Waste Minimization/Pollution Prevention

Contractor Management

Medical Surveillance

Job Hazard Analysis

Reduction of Ozone Depleting Chemicals

Waste Water Discharge Management

Analytical Laboratory Management

Environmental Sampling

Ergonomic Program

LeadershipManagement Systems III

Energy Management

Water Conservation

Green House Gas Management

ECO Product Design Criteria

Customer Relations

Supplier Management

Communications Management

Indoor Air Quality Management

Global EHS Audit Program

Level I

Level II

Level III

www.invitrogen.com

13

Compliance-Level I Prevention-Level II Leadership-Level III

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Carlsbad • • • • • •Camarillo • • • • •Eugene • • • • • • • •Frederick • • • • • •Grand Island • • • • •Madison • • • • •Scotland • • • • • • •Norway • • •New Zealand • • • • • • • •Australia • • •Japan • • • •China • • •Israel •Canada • •

The Global EHS Audit Program measures EHS perfor-

mance at all our sites against our internal requirements as

set out in the three levels of the Achievement Program, as

well as additional local EHS regulatory requirements appli-

cable to the site.

The scope of the audits is based on the achievement

level of the site, location, and major EHS risks there. All

manufacturing,R&D,anddistributionlocationsareaudited

against the three levels of achievement: compliance, pre-

vention, and leadership.

The audits are conducted by an audit team, generally

consisting of two auditors who must be independent from

the site and not subject to internal or external pressures to

influence findings and disclosures during the audit.

Our sites are audited every two years for a successive

achievement level. At the end of the audit, a report is issued

outlining any critical, major, or minor observations. The reports

also indicate responsible individuals and completion dates for

each observation.

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EHS OrganizationThe invitrogen Global EHS organization is structured to

deliver on our global EHS mission. The global organiza-

tion consists of groups acting at a global level and regional

teams acting at a site level. Our allocation of resources to

functional and regional teams provides the most efficient

support to our internal and external customers.

WhiletheGlobalEHSRegulatoryCompliancefunction

is responsible for EHS auditors at other sites. This format

ensures best practices are shared among sites, provides

career development opportunities to our global EHS team,

and preserves the independent nature of the audit func-

tion. Our current gloabel EHS contact list is on the next

page.

Global EHS training We believe there is a direct correlation between EHS training

and EHS performance. To that end, we have commitment from

leaders across Invitrogen to raise employee awareness of EHS

matters and to improve their skills.

We operate under a global EHS training plan appli-

cable to all sites. All sites are expected to follow the same

calendar of training topics. A global training schedule is

efficient for two main reasons: sites can share the training

materials for any given month and employees can attend

a required training session at other locations via remote

connections.

The EHS department delivers training using a number

of methods: classrooms, safety carts, web based, videos,

Microsoft® LiveMeeting, and posters.

In Eugene, OR, Janelle Halesworth conducts an in-lab safety discussion with Patrick Pinson, Josh Thompson, and Aleksey Rukavishnikov.

In China, our employees receive fire extinguisher training.

In Auckland, NZ, Carole Heatherbell conducts training on spill response in the production area.

www.invitrogen.com

©2008 Invitrogen Corporation. All rights reserved. These products may be covered by one or more Limited Use Label Licenses (see Invitrogen catalog or www.invitrogen.com). By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. For research use only. Not intended for any animal or human therapeutic or diagnostic use, unless otherwise stated. B-073827-r1 0408

U.S. West Coast

Leif Olsen, ManagerCarlsbad, California

Shannon Duke, Specialist ICarlsbad, California

Charles Gray, TechnicianCarlsbad, California

Jennifer Olson, ManagerEugene, Oregon

Janelle Halesworth, Specialist IEugene, Oregon

Kristina Bokody, TechnicianEugene, Oregon

Bob Baca, ManagerCamarillo, California

U.S. East Coast

Chris Holmes, Senior Manager-East CoastFrederick, Maryland

Brian Satterfield, ManagerFrederick, Maryland

Stacy Doing, ManagerGrand Island, New York

Wayde Minney, Specialist IGrand Island, New York

Kathryn Johanski, Specialist IIMadison, Wisconsin

Europe

Geoff Fowler, Manager EuropePaisley, UK

Kevin Costello, EHS OfficerPaisley, UK

Joran Baann, ManagerOslo, Norway

Global

Cristina Amorim, Senior Director Global EHSCarlsbad, California

Jeff Schatz, Senior ManagerMadison, Wisconsin

Samantha Chua, Specialist IICarlsbad, California

Nilo Noxon, Specialist IEugene, Oregon

Wendy Cecil, Senior AssociateEugene, Oregon

Open, Specialist IICarlsbad, California

AucklandNelson

Christchurch

Newcastle

Tokyo

Shanghai

Beijing

Oslo

Paisley

Merelbeke

CarlsbadCamarillo Tel Hai

MadisonBrown Deer

Frederick

Grand IslandBurlington

Sao Paolo

BrandfordEugene

Our contact listAsia Pacific

Carole Heatherbell, Manager- Asia PacificAukland, New Zealand

Yoriko Takeuchi, Specialist ITokyo, Japan

Eric Ji. ManagerBeijing, China

Li Bin, Specialist IShanghai, China

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