el u tax intracranial

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    Aachen Resonance GmbH

    Pauwelsstrasse 19, 52074 Aachen, Tel. +49-(0)241-97900905, Fax +49-(0)241-97900907, E-Mail: [email protected]

    Aachen, Germany, 14.01.2009

    First in man use of a Drug eluting Balloon for treatment of intracranial

    Stenosis

    Symptomatic intracranial stenoses have a high risk for a recurrent stroke if

    treated medically. Although angioplasty and stent placement are proposed

    treatment options, data shows a poor long-term outcome.

    Mortality rate when untreated is more than 20% in a period of 24 months.

    Prof. Juergen Reul of Beta Klinik, Bonn, Germany, used successfully and at

    the first time in the world the Elutax Balloon catheter in a case of triple A.

    basilaris stenosis. The contra lateral A. basilaris was already occluded.

    Before treatment:

    Due to the triple-lesions anatomy a stent placement was not the first option,as the tortuosity of the vessel could jeopardize the successful placement.

    After treatment with Elutax:

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    The triple restenosis is resolved and the blood flow is restored successfully.

    The Aachen Resonance Elutax Drug eluting Balloon, a life saving device, was

    used to help the patient.

    Elutax is developed especially for small vessels. The balloon is coated with 2

    microgram/mm2 pure Paclitaxel. As there is no stent mounted on the balloon,

    the pushability and the positioning of the device is facilitated compared to a

    balloon with a stent.

    The stenosis is caused by neointimal cell hyperplasia. Local administration oflipophilic paclitaxel compounds inhibits the proliferation of such cells for a long

    period.

    About Aachen Resonance:

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    Aachen Resonance is a leading European manufacturer of medical

    technology with a worldwide market presence. The company offers a

    complete line of products for treatment and advanced therapy support in

    vascular intervention, working in close cooperation with the University of

    Technology in Aachen.

    Its main focus is developing new devices with improved biocompatibility

    The field of vascular intervention consists of balloon catheters, stents, drug

    eluting stents and drug eluting balloons for coronary and peripheral

    applications.

    The company invests heavily in research and development, and is pursuing

    important, future-oriented approaches to cardiovascular therapy. Currently,

    Aachen Resonance maintains three headquarters in Europe for research,

    development and manufacturing.

    Aachen Resonance is market leader in Europe for Drug eluting balloons.

    Contact address:

    Dr. Alexander Ruebben, CEO

    Aachen Resonance GmbH

    Pauwelsstrasse 19D-52074 Aachen

    Germany

    Tel. 0049 241 97900905

    Fax. 0049 241 97900907

    www.aachen-resonance.com

    Email: [email protected]

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