eczema management. early diagnosis (pediatrics 2008) can influence child’s overall physical and...
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Eczema Management
Early diagnosis (Pediatrics 2008)
Can influence child’s overall physical and social well-being
Can effect family dynamics – physical, emotional and functional
Significance of early and effective management (Pediatrics 2008)
Early diagnosis of eczema and early appropriate treatments implemented may decrease a number of preventable problems
Treatments initiated immediately on onset can decrease severity of the skin barrier issues
Early diagnosis can be made with identifying at risk babies, ie. family history, sibling with eczema
Diagnosis and control may influence development of asthma and allergic rhinitis (Hanifin et al,poster presentation Am Ac Derm, 2007)
Key points to managementAssess severity and child’s/family QolIdentity potential triggersConsider food allergy
Reacted to a food with immediate symptomsHave moderate to severe uncontrolled eczema
despite optimum topical managementGut dysmotility (colic, vomiting, altered bowel
habits)Most children with eczema do not need to
have tests for allergies
Key points continued
Do not undergo high street or internet allergy tests – no evidence
Altering diet of breast feeding mothers may not be helpful or appropriate
Any exclusion diet in child or breast feeding mother should be under the care of a dietitian
Topical treatment
Emollients – no different from older child but more acceptance of greasier consistencies
Topical steroids – always use the lowest strength that worksFirst 2 classes generally usedOccasionally stronger classes are required for
severe flares
Steroids available in New Zealand (July 2007)Mild Moderately Potent Potent Very Potent
Hydrocortisone 0.5-2.5%
DermAid
DP Lotion-HC
Skincalm 1%
Lemnis Fatty Cream HC
Pimafucort
2-25 times as potent as 1% hydrocortisone
Eumovate
Aristocort
Viaderm KC
Kenacomb
I00-150 times as potent as 1% hydrocortisone
Beta, Betnovate, Daivobet 50/500
Fucicort
Nerisone Hydrocortisone 17-butyrate
Locoid Cream/Crelo Emulsion/Lipocream/Ointment/Scalp Lotion
Elocon C/Lotion/Oint
Advantan Cr/Oint
Up to 600 times as potent as 1% hydrocortisone
Clobetasol propionate
Dermol C/Ointment
Betamethasone dipropionate
Diprosone OV Cream/Ointment
Case oneCurrent history
6 month old boySevere, generalized eczemaWeeping, crusted lesionsNo feverStill exclusively breast fedNo solids introducedNo improvement
Daily applications of steroid creams
Several exacerbations of eczema during breast feedingIrritableDisrupted sleepFailing to thrive
Past history
Born full termUnremarkable pregnancyNormal weight and lengthMother has asthma and hayfever
Diagnosis and treatments
Severe infected atopic eczema
Allergy tests were performed
RAST, specific immunoglobulin E (IgE)
and Skin Prick Test, SPT
Positive to milk, wheat, egg, kiwifruit and peanut
Exclusion diet by the mother for 4 weeks, supervised by a
paediatric dietitian.
Exclusion diet led to clear improvement in the child’s eczema
Foods that account for more than 90% of food allergies - by age
Infant Children(2-10 years)
Older children
Cow milk Cow milk Peanut
Eggs Eggs Tree Nuts
Wheat Peanut Fish
Soy Tree Nuts Shell fish
Fish Sesame
Shell fish Pollen-associated foods
Sesame
Kiwifruit
Does food allergy resolve ?…
cow’s milkhen’s eggpeanuts, fish, seafood, …
prevalence
age3 yrs 5 yrs6 months
Case two3 year old boyMild eczemaOn a highly restricted dietDeveloped severe eczema at 2 months of age when breastfeeding was stopped
Eczema had been diffuse and resistant to topical treatments
He had an assessment by an allergistSPT showed strong positive results to milk and eggHis diet excluded egg and milk and he had an amino
acid formula (Neocate)By age 2 years his eczema was mild and he tolerated egg in baking.At that point he was seen by a general practitioner who suggested RAST testing
Case 2 continued....The results showed
Decrease in egg Sensitisation to other food allergens; soy, wheat,
fish and beefAdvised that exclusions of these other foods
would lead to further reduction in his already ‘mild’ eczema
However.......There was no reduction in the eczemaWeight dropped from 50th centile to 25th centileDeveloped significant behavioural issues
Case 2 continued....Referred back to allergy clinic
Retested and found to have outgrown both egg and milk allergies
Diet was completely liberalisedResidual eczema managed with topical
steroidsAchieved appropriate weight gainBehavioural problems improved
DiscussionDiet manipulation more pronounced under the age of 2 years with severe, early onset of eczemaCaution with allergy tests interpretation without clinical history
Over interpretation of the resultsIrrelevant sensitisation to foods rather than true allergy Stress of adhering to unnecessary food exclusionsNutritional compromiseCareful history, 4-6 week exclusion trial, then
reintroductionSupervised by a dietitian
Take home messagesBasic management principles apply across
the ages especially when severe, exacerbated or poorly controlled eczema
In the younger child help and support is required to maintain self care
Allergies may play a role but skin management is always the most important intervention