%e7%94%9f%e5%8c%96%e5%8f%8d%e5%ba%94%e7%9a%84%e4%ba%94%e8%a1%8c%e5%bd%92%e5%b1%9e

4
国际中医中药杂志20153月第37卷第3Int J Trad Chin Med, March 2015, Vol. 37, No.3 ·197· ·专题论坛· 生化反应的五行归属 徐天成 摘要五行学说提供了对事物进行系统分类的合理方法。人类体内充满了复杂的生物化学反应 体系,能否用五行学说的基本规律归纳生物化学反应体系值得探讨。在以往相关研究的基础上,本文利 用五行思想对生化反应的物质和反应类型进行分类,用简洁的中医学规律研究复杂的生化反应过程,这 种新思路对药物研究、中西医结合学科的发展等具有挖掘价值。 关键词生化反应;五行学说;中医现代化 An five elements classification of bio-chemical reactions Xu Tiancheng. Acupuncture Moxibustion and Massage(College Student of Class 2011), Nanjing University of Chinese Medicine, Nanjing 210023, China Corresponding author: Xu Tiancheng, Email: [email protected] AbstractThe five elements theory provides us a system classification of all things so we can do the research in a much reasonable way. Further more, our bodies are full of complicated bio-chemical reactions and the five elements theory should also be applicable to those reaction systems. This paper will try to make use of the five elements theory to carry on an innovative classification of different types of bio-chemical reactions with the help of the former foundation of related researches, to make the complicated bio-chemical reactions easy to understand, and point out that this kind of lately academic thought is of great significance to the medicine researches as well as the integrated traditional Chinese and western medicine. Key wordsThe bio-chemical reactions; The five elements theory; The modernization of traditional Chinese medicine 人类的生命需要物质维持,而体内所需物质 与通过饮食摄取获得的物质有很大不同,将外界 的物质转化为自身物质的同化作用过程复杂,生 物化学反应便是沟通人体内外物质的桥梁。生化 反应的物质类型和反应过程,在动物界内部乃至 动植物之间有相似性,例如三羧酸循环存在于几 乎所有需氧生物的体内。生化反应的过程如此复 杂,以至于将人体各类生化反应过程借助反应间 的共有物质联系起来时,发现这是一个相当庞大、 难以用简洁规律描述的复杂体系。倘若仔细观察, DOI: 10.3760/cma.j.issn.1673-4246.2015.03.002 基金项目:国家级大学生创新训练计划项目(201310315019作者单位:210023 南京中医药大学第二临床医学院(2011 本科生) 通信作者:徐天成,Email: [email protected] 这些不同反应之间的相互联系与制约,一环扣一 环的结构,似乎可与五行生克联系起来;倘若能 用一种简洁的规律描述纷繁复杂的生化反应间广 泛存在的联系,想必对当前的生命科学研究具有 一定的参考作用。 1 生化反应在自然界的统一性与五行生克规律 的普适性 1.1 应用五行学说对生化反应进行分类的合理 性:五行学说是把世间万物概括分类的形态学分 类体系 1,这种分类具有广泛意义,除中医学理 论体系中所描述人体的五脏、五体、五志、五液 外,中药有五味、外界有五音等。五行作为广泛 适用的分类方法已完成了大量事物的分类。那么 对于复杂的生物化学反应,能否用五行的分类方

Upload: ben-ng

Post on 02-Oct-2015

218 views

Category:

Documents


3 download

DESCRIPTION

生化反应的五行归属

TRANSCRIPT

  • 20153373 Int J Trad Chin Med, March 2015, Vol. 37, No.3 197

    An five elements classification of bio-chemical reactions Xu Tiancheng. Acupuncture Moxibustion and Massage(College Student of Class 2011), Nanjing University of Chinese Medicine, Nanjing 210023, China Corresponding author: Xu Tiancheng, Email: [email protected]

    Abstract The five elements theory provides us a system classification of all things so we can do the research in a much reasonable way. Further more, our bodies are full of complicated bio-chemical reactions and the five elements theory should also be applicable to those reaction systems. This paper will try to make use of the five elements theory to carry on an innovative classification of different types of bio-chemical reactions with the help of the former foundation of related researches, to make the complicated bio-chemical reactions easy to understand, and point out that this kind of lately academic thought is of great significance to the medicine researches as well as the integrated traditional Chinese and western medicine.

    Key words The bio-chemical reactions; The five elements theory; The modernization of traditional Chinese medicine

    DOI: 10.3760/cma.j.issn.1673-4246.2015.03.002

    201310315019

    210023 2011

    Email: [email protected]

    1

    1.1

    1

  • 198 20153373 Int J Trad Chin Med, March 2015, Vol. 37, No.3

    2

    3

    4

    1.2

    2

    5

    6

    7

    2

    8

    2

    2.1

    5

    9

    10

    11

    112

    A

    5

    13

    2.2

    3

  • 20153373 Int J Trad Chin Med, March 2015, Vol. 37, No.3 199

    1

    DNARNA

    CO-A

    CO-A ATP

    2

    () ()

    ,

    ()

    2

    214

    15

    3

    16

    5

    2

    17

  • 200 20153373 Int J Trad Chin Med, March 2015, Vol. 37, No.3

    18

    1 . [J]. ,2011,34(7):437-440,447.

    2 ,,,. [J]. ,2008,43(7):426-429.

    3 . [J]. ,1995, 10(5):38-42.

    4 ,,.

    ()[J]. -,2004,6 (1):25-29.

    5 ,. [J].

    ,2003,25(5):296-298. 6 ,. [J].

    ,1994,7(1):3-5. 7 ,,,. [J].

    ,2012,27(8):1998-2003. 8 . [J].

    ,1995,6(3):48,55-57,80. 9 ,,.

    [J]. ,2012,7(5):374-376. 10 .

    [J]. ,2002,8(5):10-12. 11 ,.

    [J]. ,2003, 9 (11):60-63. 12 ,,.

    [J]. ,2008,32(3):293-295. 13 ,,.

    [J]. ,1998,18(2):17-24. 14 ,. [J].

    ,2010,54(22):61-65. 15 ,,,.

    [J]. ,2007,42(11):669-671. 16 . [J]. ,1987,

    6(3):52-54. 17 .[N].

    ,2012-05-23(003). 18 ,,,.

    [J]. ,2013,54(1):3-7. 2014-09-23

    4 4

    18- Hydroxyferruginol(6)gaultheronoterpene(7)

    12-hydroxydehydroabietic acid(8) TNF-

    20 kg-

    (230 g)

    / 8

    Fr AHFr D(19 g) Sephadex LH-20

    ///

    TLC1(10.0 mg)3(5.0 mg)

    Fr F /

    TLC2(11.0 mg )4(3.0 mg)

    Fr E /

    TLC 5(13.0 mg ) 6(12.0 mg)

    7(11.5 mg) 8(9.0 mg)

    1 3,12-Dihydroxy-13-acetyl-8,11,13-

    podocarpatriene[]15D +64(c=0.13)IR (KBr)cm-13 3102 9252 8691 6451 6211 572

    1 489 C19H26O3 302 2

    12,19-Dihydroxy-13-acetyl-8,11,13-podocarpatriene

    []15D +46 (c =0.14)IR (KBr)cm-13 333

    2 9302 8501 6431 5691 489 C19H26O3

    302 3 4,12-Dihydroxy-13-acetyl-

    19-nor-8,11,13-podocarpatriene[]15D +13(c =0.22

    )IR (KBr)cm-13 4732 9362 8501 6361

    6081 5671 4891 3151 188887806 C18H24O3

    288 4 8,18-Dihydroxy-9(11),

    13-abietadien-12-one[]15D -3(c=0.13)

    IR (KBr) cm-13 4462 9252 8531 7171 6531 384

    C20H30O3 318

    [Phytochemistry Letters,2014,8:6-9]