JAK2 Mutation Analysis can detect a mutation (altered JAK2 gene) within your blood or bone marrow which can indicate the presence of a myeloproliferative neoplasm (MPN).perform a bone marrow biopsy or take a blood sample to obtain specimens for testing, and then send the specimens to a laboratory for analysis. Initial results can typically be obtained from the blood sample. f your result is abnormal:An abnormal test result typically indicates the presence of a myeloproliferative neoplasm (MPN) in your bone marrow or blood. A JAK2 mutation is present in approximately: 95% of cases with polycythemia vera (PV) 50% of cases with primary myelofibrosis (PMF) 40-50% of cases with essential thrombocythemia (ET)Oxygen Affinity, a red cell characteristic determined by both hemoglobin, and cytosolic composition is measured with the Hemox analyzer. The P50 is a conventional measure of the affinity of hemoglobin for oxygen. The oxyhemoglobin dissociation curve relates oxygen saturation (SO2) and partial pressure of oxygen in the blood (PO2). The PO2 at which the hemoglobin is 50% saturated, typically about 26-28 mmHg for a healthy person, is known as the P50. In the presence of disease or other conditions that change the hemoglobin's oxygen affinity and, consequently, shift the curve to the right or left, the P50 changes accordingly. An increased P50 indicates a rightward shift of the curve, which means that a larger partial pressure is necessary to maintain a 50% oxygen saturation. This indicates a decreased affinity. Conversely, a lower P50 indicates a leftward shift and a higher affinity.Carboxyhemoglobin (SpCO) is a breakthrough measurement that allows clinicians to noninvasively and immediately detect elevated levels of carbon monoxide in the blood-facilitating earlier diagnosis and treatment for patients poisoned by carbon monoxide. This test measures the amount of carboxyhemoglobin (carbon monoxide and hemoglobin) in blood. It is used to diagnose and manage carbon monoxide poisoning[1].

RDW stands for Red (Blood Cell) Distribution Width, an index for the degree of variability in the size and shape of your red blood cells. Recent studies are showing it to be a powerful indicator of overall health and the risk of death from multiple causes.Meningkat pada anemia defiiensi iron gangguan tiudrdan vit b12, cardiovascular dz, cance, ulcerative colitis.