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Dr : Osama Badry Cardiology /Anticogaulation Coordinator Incharge of Anticoagulation Service AWH-HMC/Qatar Pharmacist - Directed Anticoagulation Service : Quality Of care

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Dr : Osama BadryCardiology /Anticogaulation CoordinatorIncharge of Anticoagulation Service AWH-HMC/Qatar

Pharmacist - Directed Anticoagulation Service

: Quality Of care

“The degree to which health services for individuals and populations increase the likelihood of desired health outcomes and are consistent with current professional knowledge.”

Institute of Medicine. (2001). National Academy Press

Quality : Definition

“The provision of the necessary health care service to the appropriate person at appropriate time, and using the best means with the objectives of getting the best results for each individual patient, and the community at large.”

Qatar Supreme Council of Health

Effective Patient-centered

Timely Efficient

Quality of Care

Scientific Knowledg

e

Waiting Time

Patients’ Needs

Wasteful

Practices

Warfarin : Effective rat poison

Warfarin Therapy

Warfarin –Most widely used vitamin K antagonists(VKAs) worldwide in the prevention of treatment of blood clots. it’s used complicated by various factors

Ansell J .et.al 2004,Bungard TJ,et.al.2009,Hamby L ,et.al 2000

Utilizing the correct intensity and maintaining the patient in the therapeutic-determinant of its therapeutic effectiveness and safety

Ansell J .et.al 2004,Yi W.et.al.2008,kamali F.et.al,2010

3 primary models available for managing oral anticoagulant care are usual medical care, anticoagulation clinic, patient self management

Wilson SJ.et.al 2003

Question

Is the pharmacist managed anticoagulation more effective than usual care?

Anticoagulation Clinic (AC)

Anticoagulation management services(AMSs) (i.e.; anticoagulation clinics) is accepted as

gold standard and one of the approaches to improve anti Coagulant care

Ansell J et al. 2001Pharmacist Managed AMS in comparison to

other clinics (physician / Nurses) :Achieve superior anticoagulation control Favorable impact on hospitalization

Ruud KM. et al. 2010

Pharmacist Managed AC

Pharmacist-staffed Acs provided patient education, a more consistent monitoring and early recognition of risk factors.

Chamberlain MA. et.al .2001

Pharmacist –managed AC service demonstrated decreased advers events(39-47 % bleeding) and reduced hospital costs (USD 375-1620 per patient).

Saokaew S .2010, You JHS CA.et al .2008

Quality Team

Disadvantage of Usual Care

No systematic approach for tracking and scheduling INRs.No specific dosing nomogram or protocol are utilized ; only

individual physician knowledge and experience with management of warfarin is utilized.

Patients who are not getting their lab work done routinely may not discovered until a doctor’s appointment or a prescription renewal.

Long waiting time resulted in patient’ frustration and low satisfaction.

No structured education or counseling for patients and/or their families.

Unavailability of the treating physicians. No active participation for other health care providers e.g.

Pharmacists, Patient educators and dieticians. Follow-up appointment depends on physician’s scheduling.No structured evaluation of service e.g non adherence to warfarin

therapy.

Outpatient Management

Conclusion: The pharmacist-managed anticoagulation program within a family practice clinic compared to usual care by the physicians achieved significantly better INR control as measured by the percentage of time patients’ INR values were kept in both the therapeutic and expanded range. Based on the results of this study, a collaborative family practice clinic using pharmacists and physicians may be an effective model for anticoagulation management with these results verified in future prospective randomized studies.

Inpatient

Management

Impact of PDAS on Quality and Safety of HIT Management

Outcome with pharmacist – and physician- managed warfarin mediated anticoagulation

Efficacy with pharmacist –managed in-hospital anticoagulation

Garwood et al 2008

Pharmacist-Managed

Anticoagulation clinic

From Zero to star of

excellence

Process of implementation

Pharmacy Director Idea

Cardiology Champion

Multdisciplinary

Subcommittee

Pharmacy & Therapeutic Committee

Senior Executive Clinical

complexityProvision of

resources

and support

Challenges

Resources

Physician resistance

Patient satisfaction

Referral and first appointment

Anticoagulation clinic statisticsTotal Number of Patients May 2013- September 2014

Indication NoAF 59

MVR 9

AVR 8

DVR 5

L-V thrombus 7

Pulmonary hypertension 2

DVT 38

Pulmonary Embolism 28

Portal vein thrombosis 2

Stroke 3

APS 3

Sever AS,MR 1

Right portal vein thrombosis 1

Post MI , LV aneurysm 1

IVC 1

Low EF 1

Cerebral vein thrombosis 2

Total 171

Anticoagulation clinic statistic per Indication May 2013- September 2014

Month No

May /2013 11

June/2013 47

July/2013 79

August /2013 50

September/2013 85

October/2013 53

November/2013 74

December/2013 96

JANUARY /2014 86

February /2014 105

March/2014 101

April/2014 98

May/2014 97

June/2014 95

July/2014 104

August/2014 106

September/2014 123

TOTAL 1410

VISITS NO /MAY 2013-SEPTEMBER 2014

VISITS NO /MAY 2013-SEPTEMBER 2014

Month NoMay /2013 12

June/2013 11

July/2013 28

August /2013 27

September/2013 19

October/2013 21

November/2013 18

December/2013 22

JANUARY /2014 12

February /2014 20

March/2014 13

April/2014 27

May/2014 37

June/2014 53

July/2014 24

August/2014 36

September 45

TOTAL 425

INTERVENTIONS

Interventions

Research done in collaboration with Qatar university, ‘’Satisfaction and quality of life of patients attending an ambulatory pharmacist-managed anticoagulation clinic in Qatar’’, see the supporting evidence.

The quantitative improvement was done by calculation of TTR (time in therapeutic range) a metric of how well patients are managed on warfarin therapy by using software program, the result is 77.8

Another two ongoing researches were accepted by research center

1-‘’evaluation of clinical and economical outcomes at pharmacist versus physicians –based anticoagulation outpatient clinic and its impact on the cardiovascular disease management in Qatar””

2-‘’ The Effect of Genetic Variants on Warfarin Dosing and Its Impact on Cardiovascular Outcomes in Qatar’’

Quality Evidence

Why We Are Successful

Strong and effective leadership Multidisciplinary Team Quality Improvement First clinic run by a clinical pharmacist in

HMC/ QATAR  

Progress does not involve replacing one

theory that is wrong with one that is right,

rather it involves replacing one theory that

is wrong with one that is more subtly wrong.

Hawkins Law