dr. farzad afzali,pregnancy doppler

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    Presented by:

    Dr. Farzad AfzaliKasra medical imaging center

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    An early stage in fetal adaptation to

    hypoxemia

    increased blood flow in DV to protect the brain,heart, and adrenals

    central redistribution of blood flow

    ( brain-sparing reflex)

    reduced flow to the peripheral and placentalcirculations

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    Under physiologic conditions, 60 to 70

    percent of umbilical venous blood in the

    human fetus is distributed to the liver and the

    remainder to the heart.

    With chronic hypoxemia, this proportion may

    be modulated so that a larger proportion of

    umbilical venous blood can bypass the liver to

    reach the heart

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    The middle cerebral artery (MCA) in the fetal brain

    Normally high-impedance

    Most accessible to U/S imaging

    More than 80% of cerebral blood

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    Average of both MCAs must be calculated for more

    precise result.

    Compression of the fetal head causes increasing arterial

    resistance.( false negative of IUGR)

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    The best predictor for fetal acidemia

    is PI of thoracic aorta.

    The best predictor of fetal hypoxia is

    PI of MCA.

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    The damage that obliterate small muscular arteries in

    placental tertiary stem villi

    absent flow or even reversed flow, suggestive more

    than 70% damage of placenta.

    commonly associated with severe IUGR and

    oligohydramnios

    Waveforms obtained from the placental end of cord

    show more end-diastolic flow, thus lower RI & PI,than waveforms obtained from the abdominal cord

    insertion. (No significance on clinical practice)

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    Velocimetry of uterine artey should be obtained

    after the vessel crosses the hypo gastric artery and

    vein, at the uterus-cervical junction, before it

    divides to cervical and uterine branches.

    The best predictor of PIH is notch in the uterine

    artery & RI>61.5 % after 22 w of gestation.

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    Venous indices reflect : ventricular function

    Fetal hypoxia

    Myocardial lactic acidosis

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    DV a wave decrease

    Reverse EDF UA -- Reverse a wave DV

    Pulsatile UV

    Constriction of cerebral circulation

    Death within 96 hours

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    At the level of AC measuring, ductus venosus canbe identified as it branches from hepatic vein.

    It has high speed flow with biphasic waveform.

    The first phase corresponding ventricular systole,the second phase to early diastole and nadir to theatrial kick.

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    Umbilical vein displays pulsatility in first trimester

    but this disappears with advancing gestation in the

    pregnancy unaffected by FGR

    http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1530021&dopt=Abstracthttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1530021&dopt=Abstract
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    In clinical practice, it is necessary to carry out serial

    Doppler investigations to estimate the duration of

    fetal blood flow redistribution.

    The onset of abnormal venous Doppler resultsindicates deterioration in the fetal condition and

    iatrogenic delivery should be considered

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    Preterm growth restricted fetuses with elevated

    umbilical artery Doppler resistance have an overall

    perinatal mortality rate of 5 6percent .This rate increases to 5percent when end-diastolic

    velocity is absent.

    and rises to 38 8percent when venous Doppler indicesbecome abnormal (predominantly due to an increase in

    the rate of stillbirth).

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