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The origin of angina pectoris

But V. I.

(E- mail: vit.but@mail.ru)

Department of physiology IEM Russian Academy of Medical Science

Saint Petersburg

We observed patients with ischemia illness of heart. Practically all periodically

had pains in the field of heart. Patients describe a angina pectoris as spasmodic,

strong compression. Naturally there is a question on an origin of these pains. It

is known, that similar pains arise at a spasm muscles of calf, smooth muscles of a

gullet.Now the receptors of pains in the heart is not known [3]. Where and how

the receptors, informing about damage of a myocardium have an ending on

periphery? On what they inform?On this question the answer is given in E.K .Plechkovoj's works and other

authors [5]. Receptors on myocardial cells are free, the endings such as muscularspindles [fig. 1].

The endings closely adjoin to myocardial cells and can, similarly to

muscular spindles in skeletal muscles to testify to process of a spasm

myocardiums cells.Frequency of impulses on the sensitive nervous terminations on muscular cells

everywhere sharply amplifies at a pressure of these cells (2).

Who has felt pains at a spasm muscles of calf know that the pain can arisesharply and suddenly. It reminds a pain in the field of heart.

The ischemia of the free nervous terminations, for example, in a skin, doesnot result in a pain. Everyone can check up it on himself, having compressed on 10

minutes a site of a skin between fingers. Only the arrangement of the endings on a

muscular cell can result in sensation of a pain.Such pain can be observed and at a spasm to smooth muscles of a gullet. This

pain also is removed by nitroglycerine, induced by cold drinks, negative emotions,

gives to the left hand, it happens at night more often.

Contraction a part myocardium does not surprise. About it wrote:

1. F.Z.Meerson at experimental stress at dogs, 2. I.K. Bogdanovich, etc. [1] marked: In a fabric of a myocardium at sudden

death and a heart attack of a myocardium it was observed damage myocardial cells

with rough strips of reduction .3. L.M. Nepomnyaschy [4] writes that in experiment and on body material the

following types of damage myocardial cells arisen primarily are observed, firstminutes of an ischemia: contraction myocardial cells 1 both 11, and 111 degrees

with the further outcome in partial infarction with contraction separate groups

myocardial cells.

The muscular spasm myocardial cells allows to explain such kinds of pains inthe field of heart, as a angina pectoris on a cold, a angina on physical loading, to

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similarly muscular spasm calf muscles at swimming.

The angina pectoris, stenocardia, attack pain in a myocardium, , sometimesobserved by us at patients with ischemia illness of heart , are caused by asudden spasm of myocardial cells with a simultaneous spasm coronary arteries

with the subsequent ischemia causes sometimes the sudden death.

Conclusion

The angina pectoris , stenocardia arises in area of muscular spindles , the

ending on myocardial cells .

The literature

1. Bogdanovich N.K., etc., In the book: Sudden death, Vilnius, 1984.

2. But V. I., Physiol. J., 57, 1, 85-88,1971.

3. Kozlov K.L., V. Shanin. Ischemic illness of heart, 2002.

4. Nepomnjashchih L.M. The major pathological processes in heart, 1991.

5. Plechcova E.K. Nervous of heart, Klin. Medicine, 33, 19,

p. 28,1941.

7. Shvalyov V.N., etc. Morphological bases nervous hearts, M., 1991.

Fig. 1 Sensitive ending in a myocardium, a nervous - muscular spindle.