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The clinical research of early diagnosis and ultimately the treatment of Alzheimer’s disease
101001061 許一仁103001004 董冠廷103001019 詹鎮遠103001044 陳柏廷
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Dementia
• Suffers memory difficulty• Can’t feed or dress themselves• Can’t recognize the person sitting next to
them have been their spouse for thirty or forty years
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Dementia
• Unfortunately, this is the stage where we are typically doing our clinical trials. • There’s already been years of irreversible
brain damage.
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Mild cognitive impairment (MCI)
• MCI = prodromo(?) Alzheimer’s• Not all will progress to Alzheimer’s disease• A significant risk factor, and 15 percent of them
will move toward Alzheimer dementia every year
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Mild cognitive impairment (MCI)
• Have already started to do clinical trials at this stage of disease• However, even mild cognitive
impairment might still be too late
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The Amyloid plaques
• We already know that Amyloid must play an important role in Alzheimer’s disease because the genetics drives us this way.• Unfortunately we don’t have all the
answers.
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Why would one want to detect and find out that one’s gonna get Alzheimer’s
• Disease ten or twenty years before they do when there’s nothing we can do about it?• Look at other diseases: cancer, cardiovascular
disease, HIV-AIDS, diabetes, osteoporosis, stroke• We have successes when we treat before we
can see symptoms.